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Receptor
PDB id Resolution Class Description Source Keywords
2ZJ5 2.4 Å EC: 3.6.1.- ARCHAEAL DNA HELICASE HJM COMPLEXED WITH ADP IN FORM 1 PYROCOCCUS FURIOSUS RECA FOLD ATP-BINDING HELICASE HYDROLASE NUCLEOTIDE- BINDING
Ref.: ATOMIC STRUCTURES AND FUNCTIONAL IMPLICATIONS OF THE ARCHAEAL RECQ-LIKE HELICASE HJM BMC STRUCT.BIOL. V. 9 2 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADP A:801;
Valid;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
SO4 A:901;
A:902;
A:903;
A:904;
A:905;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2ZJ5 2.4 Å EC: 3.6.1.- ARCHAEAL DNA HELICASE HJM COMPLEXED WITH ADP IN FORM 1 PYROCOCCUS FURIOSUS RECA FOLD ATP-BINDING HELICASE HYDROLASE NUCLEOTIDE- BINDING
Ref.: ATOMIC STRUCTURES AND FUNCTIONAL IMPLICATIONS OF THE ARCHAEAL RECQ-LIKE HELICASE HJM BMC STRUCT.BIOL. V. 9 2 2009
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 28 families.
1 2ZJ5 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 26 families.
1 2ZJ5 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 24 families.
1 2ZJ5 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 452
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 HEJ 0.9 1
3 ATP 0.9 1
4 A2D 0.895522 0.971831
5 5FA 0.887324 1
6 AQP 0.887324 1
7 AP5 0.884058 0.971831
8 B4P 0.884058 0.971831
9 BA3 0.869565 0.971831
10 AN2 0.84507 0.985915
11 AT4 0.84507 0.958904
12 M33 0.833333 0.958333
13 ACQ 0.826667 0.972222
14 A 0.823529 0.971429
15 AMP 0.823529 0.971429
16 ACP 0.821918 0.972222
17 6YZ 0.818182 0.972222
18 APR 0.810811 0.971831
19 AR6 0.810811 0.971831
20 ANP 0.802632 0.972222
21 SAP 0.8 0.945946
22 AGS 0.8 0.945946
23 AD9 0.8 0.972222
24 ADX 0.783784 0.873418
25 CA0 0.783784 0.945205
26 TAT 0.779221 0.958904
27 T99 0.779221 0.958904
28 50T 0.773333 0.958333
29 ABM 0.763889 0.917808
30 APC 0.763158 0.958904
31 PRX 0.763158 0.893333
32 ATF 0.759494 0.958904
33 A22 0.753086 0.985915
34 AP2 0.743243 0.958904
35 A12 0.743243 0.958904
36 SRA 0.736111 0.918919
37 ADQ 0.73494 0.945205
38 25L 0.732558 0.985915
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 A3R 0.714286 0.907895
44 ATR 0.708861 0.971429
45 ADP PO3 0.708861 0.943662
46 PAP 0.708861 0.985714
47 SRP 0.707317 0.906667
48 7D3 0.706667 0.905405
49 25A 0.702381 0.971831
50 9X8 0.697674 0.92
51 OAD 0.697674 0.945205
52 RBY 0.6875 0.932432
53 ADV 0.6875 0.932432
54 00A 0.686047 0.883117
55 OOB 0.682353 0.931507
56 5SV 0.682353 0.848101
57 8QN 0.682353 0.931507
58 3OD 0.681818 0.945205
59 BIS 0.681818 0.933333
60 ALF ADP 0.674699 0.87013
61 ADP ALF 0.674699 0.87013
62 AMO 0.674419 0.932432
63 4AD 0.674419 0.92
64 PAJ 0.674419 0.884615
65 GAP 0.670732 0.893333
66 MAP 0.670588 0.945946
67 AHX 0.666667 0.896104
68 VO4 ADP 0.666667 0.931507
69 DLL 0.666667 0.931507
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LMS 0.653333 0.82716
75 LAD 0.651685 0.860759
76 WAQ 0.651685 0.883117
77 B5V 0.651685 0.906667
78 PR8 0.651685 0.85
79 ITT 0.65 0.943662
80 7D4 0.65 0.905405
81 G5P 0.648936 0.921053
82 XYA 0.647059 0.84507
83 ADN 0.647059 0.84507
84 RAB 0.647059 0.84507
85 1ZZ 0.644444 0.839506
86 ME8 0.644444 0.839506
87 FYA 0.644444 0.905405
88 NB8 0.644444 0.896104
89 TXA 0.644444 0.932432
90 6AD 0.642857 0.909091
91 ADP BMA 0.640449 0.918919
92 G3A 0.638298 0.921053
93 DAL AMP 0.632184 0.905405
94 AFH 0.631579 0.884615
95 9SN 0.630435 0.871795
96 9ZA 0.625 0.907895
97 DQV 0.625 0.958333
98 9ZD 0.625 0.907895
99 GTA 0.625 0.886076
100 YAP 0.623656 0.894737
101 B5M 0.623656 0.894737
102 FA5 0.623656 0.906667
103 B5Y 0.623656 0.894737
104 UP5 0.622449 0.92
105 HFD 0.619048 0.945946
106 XAH 0.617021 0.839506
107 AV2 0.616279 0.917808
108 AOC 0.615385 0.821918
109 48N 0.612245 0.896104
110 4UV 0.610526 0.894737
111 6V0 0.606061 0.896104
112 NAI 0.606061 0.907895
113 DND 0.606061 0.932432
114 NAX 0.606061 0.873418
115 NXX 0.606061 0.932432
116 TXD 0.606061 0.907895
117 5N5 0.605634 0.819444
118 5AS 0.604938 0.77907
119 A4P 0.60396 0.843373
120 DAT 0.60241 0.905405
121 A2R 0.602273 0.985915
122 TXE 0.6 0.907895
123 OMR 0.6 0.851852
124 4UU 0.597938 0.894737
125 GA7 0.597938 0.906667
126 A A 0.597826 0.944444
127 A4D 0.597222 0.819444
128 5CD 0.597222 0.805556
129 AP0 0.594059 0.896104
130 4TC 0.594059 0.896104
131 A3P 0.592593 0.971429
132 T5A 0.592233 0.841463
133 139 0.592233 0.873418
134 7D5 0.592105 0.878378
135 ATP A A A 0.589474 0.930556
136 LAQ 0.585859 0.839506
137 MYR AMP 0.585106 0.817073
138 F2R 0.580952 0.864198
139 YLP 0.58 0.819277
140 UPA 0.578431 0.907895
141 7DD 0.578313 0.985714
142 3AM 0.576923 0.929577
143 ADJ 0.576923 0.851852
144 COD 0.575472 0.811765
145 NAD 0.575472 0.931507
146 3AT 0.574713 0.971831
147 JB6 0.574468 0.883117
148 4UW 0.574257 0.860759
149 EP4 0.573333 0.753247
150 A2P 0.573171 0.957143
151 CNA 0.571429 0.932432
152 TYM 0.568627 0.906667
153 PPS 0.568182 0.873418
154 DTA 0.565789 0.786667
155 M2T 0.565789 0.734177
156 AR6 AR6 0.565657 0.917808
157 A3D 0.564815 0.918919
158 80F 0.564815 0.841463
159 3DH 0.564103 0.773333
160 G5A 0.563218 0.77907
161 YLB 0.563107 0.819277
162 YLC 0.563107 0.839506
163 AMP DBH 0.561224 0.893333
164 TYR AMP 0.561224 0.87013
165 MTA 0.558442 0.773333
166 DTP 0.556818 0.905405
167 AHZ 0.554455 0.817073
168 NA7 0.553191 0.958904
169 IOT 0.552381 0.831325
170 ZAS 0.55 0.766234
171 7MD 0.55 0.8625
172 ARG AMP 0.55 0.829268
173 IMO 0.548781 0.929577
174 YLA 0.54717 0.819277
175 NAE 0.544643 0.894737
176 TAD 0.544554 0.884615
177 A5A 0.544444 0.807229
178 2AM 0.544304 0.943662
179 TSB 0.543478 0.819277
180 6RE 0.54321 0.759494
181 AYB 0.542056 0.809524
182 NAQ 0.539823 0.871795
183 V3L 0.539326 0.971831
184 SSA 0.538462 0.8
185 AF3 ADP 3PG 0.538462 0.8375
186 ZID 0.535088 0.918919
187 LPA AMP 0.533981 0.817073
188 52H 0.532609 0.77907
189 VMS 0.532609 0.788235
190 54H 0.532609 0.788235
191 BTX 0.53211 0.841463
192 A3N 0.53012 0.786667
193 J7C 0.53012 0.769231
194 5X8 0.528736 0.763158
195 BT5 0.527273 0.831325
196 8X1 0.526882 0.752809
197 5CA 0.526882 0.8
198 53H 0.526882 0.77907
199 ARU 0.526316 0.860759
200 EAD 0.525862 0.873418
201 RGT 0.525253 0.958904
202 OVE 0.52439 0.905405
203 S4M 0.52381 0.666667
204 7DT 0.522727 0.985714
205 GDP 0.522222 0.92
206 DDS 0.522222 0.878378
207 AVV 0.521277 0.896104
208 NDE 0.521008 0.932432
209 7MC 0.518868 0.841463
210 DSH 0.518072 0.725
211 MAO 0.517647 0.759036
212 NSS 0.515789 0.8
213 DSZ 0.515789 0.8
214 LSS 0.515789 0.761364
215 P5A 0.515464 0.744444
216 DZD 0.513514 0.884615
217 NVA LMS 0.510417 0.752809
218 9K8 0.510204 0.714286
219 12D 0.509615 0.785714
220 M24 0.508772 0.85
221 YLY 0.508772 0.809524
222 P1H 0.508333 0.851852
223 5AD 0.506849 0.746479
224 GJV 0.505882 0.75
225 LEU LMS 0.505155 0.752809
226 AMP NAD 0.504505 0.905405
227 4TA 0.504505 0.807229
228 G A A A 0.504505 0.871795
229 NAJ PZO 0.504425 0.848101
230 GSU 0.5 0.77907
231 128 0.5 0.776471
232 KAA 0.5 0.752809
233 71V 0.5 0.907895
234 A3G 0.5 0.8
235 NDC 0.5 0.871795
236 7D7 0.5 0.743243
237 N0B 0.495726 0.819277
238 NJP 0.495495 0.945946
239 ODP 0.495495 0.909091
240 2SA 0.494624 0.932432
241 6C6 0.494505 0.881579
242 SFG 0.494382 0.75
243 0WD 0.491071 0.921053
244 YSA 0.490196 0.77907
245 PO4 PO4 A A A A PO4 0.489796 0.902778
246 SAM 0.48913 0.690476
247 6IA 0.48913 0.8375
248 A7D 0.488636 0.776316
249 6FA 0.488 0.841463
250 FB0 0.487805 0.804598
251 NAJ PYZ 0.487179 0.807229
252 A5D 0.483516 0.786667
253 IDP 0.483516 0.918919
254 SA8 0.483516 0.707317
255 PGS 0.483146 0.883117
256 MHZ 0.483146 0.697674
257 DA 0.482353 0.878378
258 D5M 0.482353 0.878378
259 NEC 0.482353 0.746667
260 NIA 0.481928 0.822785
261 Y3J 0.480519 0.726027
262 8PZ 0.480392 0.8
263 FAD 0.480315 0.851852
264 FAS 0.480315 0.851852
265 FDA 0.48 0.833333
266 N6P 0.479592 0.915493
267 GGZ 0.479167 0.825
268 U A 0.478261 0.907895
269 SAH 0.478261 0.74359
270 SAI 0.478261 0.734177
271 A G 0.477876 0.883117
272 NPW 0.477477 0.886076
273 NDP 0.477477 0.921053
274 AAM 0.476744 0.971429
275 C2R 0.47561 0.90411
276 AMZ 0.47561 0.916667
277 A A A 0.474747 0.905405
278 GTP 0.473684 0.92
279 U A G G 0.473684 0.883117
280 SMM 0.473684 0.686047
281 NZQ 0.473214 0.909091
282 TXP 0.473214 0.921053
283 A3S 0.47191 0.810811
284 SFD 0.46875 0.734043
285 AIR 0.468354 0.901408
286 AAT 0.468085 0.707317
287 EEM 0.468085 0.690476
288 J7V 0.466667 0.833333
289 Z5A 0.466667 0.77907
290 7C5 0.466667 0.818182
291 62F 0.465649 0.8625
292 HDV 0.463158 0.893333
293 FAY 0.462121 0.8625
294 A3T 0.461538 0.821918
295 ETB 0.461538 0.833333
296 DCA 0.461538 0.823529
297 A6D 0.46 0.722892
298 A U 0.459459 0.87013
299 GEK 0.459184 0.7375
300 6K6 0.459184 0.930556
301 RFL 0.458647 0.821429
302 NAP 0.458333 0.945205
303 S7M 0.458333 0.690476
304 4YB 0.457944 0.761364
305 WSA 0.454545 0.788235
306 TAP 0.454545 0.907895
307 FNK 0.454545 0.804598
308 COA 0.453782 0.823529
309 0T1 0.453782 0.823529
310 101 0.453488 0.878378
311 XNP 0.452174 0.873418
312 NA0 0.45082 0.932432
313 7RP 0.448276 0.928571
314 GP3 0.446809 0.921053
315 TM1 0.446602 0.77381
316 APU 0.446429 0.894737
317 PUA 0.445378 0.884615
318 V1N 0.443396 0.917808
319 7RA 0.443182 0.957747
320 COS 0.442623 0.804598
321 AMX 0.442623 0.833333
322 30N 0.442623 0.752688
323 CAO 0.442623 0.795455
324 QQY 0.44186 0.815789
325 ACK 0.44186 0.861111
326 649 0.441441 0.744444
327 0UM 0.44 0.698795
328 NHD 0.439655 0.905405
329 CMX 0.439024 0.823529
330 SCO 0.439024 0.823529
331 GCP 0.438776 0.896104
332 8BR 0.438202 0.906667
333 GNH 0.4375 0.907895
334 8Q2 0.4375 0.772727
335 3AD 0.4375 0.805556
336 NVA 2AD 0.43617 0.759494
337 62X 0.435644 0.666667
338 FCX 0.435484 0.795455
339 ACO 0.435484 0.795455
340 FAM 0.435484 0.804598
341 9JJ 0.434783 0.8625
342 GNP 0.434343 0.896104
343 9GM 0.434343 0.896104
344 NMX 0.433071 0.76087
345 MGP 0.43299 0.884615
346 26A 0.432099 0.763158
347 HAX 0.432 0.804598
348 K15 0.431373 0.682353
349 DG1 0.430894 0.921053
350 1DG 0.430894 0.921053
351 QQX 0.430233 0.805195
352 2VA 0.430108 0.8
353 S8M 0.43 0.759494
354 2MC 0.429688 0.769231
355 6G0 0.428571 0.884615
356 P5F 0.428571 0.823529
357 FYN 0.428571 0.823529
358 3KK 0.428571 0.804598
359 A C A C 0.428571 0.848101
360 7L1 0.427419 0.795455
361 FAI 0.426966 0.916667
362 RMB 0.426966 0.873239
363 AS 0.426966 0.833333
364 1RB 0.425287 0.885714
365 CA6 0.425197 0.729167
366 SOP 0.425197 0.804598
367 OXK 0.425197 0.804598
368 MCD 0.425197 0.804598
369 COK 0.425197 0.804598
370 G1R 0.424242 0.907895
371 SXZ 0.423077 0.710843
372 CC5 0.423077 0.816901
373 F2N 0.422535 0.813953
374 EO7 0.422222 0.788235
375 ANZ 0.422018 0.8
376 1VU 0.421875 0.795455
377 CMC 0.421875 0.804598
378 CO6 0.421875 0.804598
379 ZDA 0.421053 0.864865
380 GKE 0.420561 0.884615
381 GDC 0.420561 0.884615
382 GDD 0.420561 0.884615
383 NFD 0.420168 0.883117
384 GSP 0.42 0.873418
385 D3Y 0.42 0.789474
386 MC4 0.419847 0.76087
387 3D1 0.419753 0.773333
388 3L1 0.419753 0.773333
389 FA9 0.41958 0.864198
390 5GP 0.419355 0.906667
391 G 0.419355 0.906667
392 KB1 0.419048 0.698795
393 CAJ 0.418605 0.804598
394 SCD 0.418605 0.823529
395 CMP 0.417582 0.901408
396 2BA 0.417582 0.915493
397 SO8 0.416667 0.789474
398 VRT 0.416667 0.769231
399 N01 0.416667 0.905405
400 IVC 0.415385 0.813953
401 1HE 0.415385 0.786517
402 A1S 0.415385 0.804598
403 BCO 0.415385 0.804598
404 3HC 0.415385 0.813953
405 MLC 0.415385 0.804598
406 NMN AMP PO4 0.415254 0.87013
407 2FA 0.414634 0.813333
408 MGO 0.414141 0.860759
409 3NZ 0.413462 0.782051
410 COO 0.412214 0.804598
411 MCA 0.412214 0.795455
412 YE1 0.412214 0.813953
413 CAA 0.412214 0.813953
414 GAV 0.411765 0.884615
415 PRT 0.411215 0.931507
416 JLN 0.411111 0.890411
417 P2P 0.411111 0.902778
418 ZZB 0.410256 0.77381
419 SP1 0.409091 0.842105
420 RP1 0.409091 0.842105
421 2CP 0.409091 0.795455
422 SCA 0.409091 0.804598
423 103 0.409091 0.837838
424 PAX 0.408 0.829268
425 FAD NBT 0.407143 0.75
426 COW 0.406015 0.795455
427 3CP 0.406015 0.804598
428 IRC 0.406015 0.813953
429 BYC 0.406015 0.804598
430 CA8 0.406015 0.729167
431 1GZ 0.406015 0.795455
432 COF 0.406015 0.786517
433 HGG 0.406015 0.804598
434 2KQ 0.406015 0.786517
435 G2P 0.405941 0.884615
436 SLU 0.404959 0.770115
437 U A C C 0.404959 0.858974
438 RBZ 0.404494 0.849315
439 1CZ 0.404412 0.795455
440 FAQ 0.402985 0.804598
441 BCA 0.402985 0.795455
442 4CA 0.402985 0.795455
443 MTP 0.402439 0.730769
444 8OD 0.402062 0.945205
445 CO7 0.401515 0.804598
446 GRA 0.4 0.804598
447 G2R 0.4 0.884615
448 ENQ 0.4 0.916667
449 CNV FAD 0.4 0.8
450 GMV 0.4 0.896104
451 HXC 0.4 0.786517
452 HF7 0.4 0.893333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2ZJ5; Ligand: ADP; Similar sites found with APoc: 580
This union binding pocket(no: 1) in the query (biounit: 2zj5.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 4ZG4 VO4 ADP 0.972222
2 2FSH ANP 1.11111
3 1Z6T ADP 1.35364
4 1LVK MNT BEF 1.38889
5 5WC2 ADP 1.38889
6 1QF5 GDP 1.39211
7 1QF5 RPL 1.39211
8 1DAR GDP 1.44718
9 1KK1 GNP 1.46341
10 4PFO ADP 1.52778
11 1GNI OLA 1.53846
12 5WRI A3P 1.5625
13 4EIL NDP 1.59011
14 4YJ1 ADP 1.62602
15 5WRJ A3P 1.65016
16 5TSH ANP 1.70068
17 5TSH ADP 1.70068
18 1T5C ADP 1.7192
19 5A04 NDP 1.76991
20 5A04 BGC 1.76991
21 4KVL PLM 1.77134
22 5FTB ANP 1.84758
23 1OS1 PYR 1.85185
24 3FKQ ATP 1.87668
25 1NHX FTB 1.92
26 1NHX PEP 1.92
27 2GMV UN8 1.92
28 2GMV PEP 1.92
29 1QO8 FAD 1.94346
30 5OC1 FAD 1.9469
31 4IHQ ADP 1.94932
32 3NHB ADP 1.96078
33 2FAH GDP 1.97368
34 2GKS ADP 2.01465
35 4REL KMP 2.01794
36 2XT3 ADP 2.03488
37 5H7J GCP 2.08333
38 4BR5 ANP 2.08333
39 2AWN ADP 2.09974
40 2B8W ALF 5GP 2.13415
41 4H1V GNP 2.16802
42 4YS0 ADP 2.22222
43 2WPF WPF 2.22222
44 2WPF FAD 2.22222
45 5MZN ADP 2.22222
46 3GZ9 D32 2.23048
47 3MD0 GDP 2.25352
48 3GJ4 GDP 2.26244
49 3GJ0 GDP 2.26244
50 3GJ5 GDP 2.26244
51 3GJ3 GDP 2.26244
52 1BZL GCG 2.26337
53 2QQF A1R 2.27273
54 4UTG ANP 2.31214
55 1IBR GNP 2.31481
56 5L3V GDP 2.34114
57 4PX9 ADP 2.39726
58 4WZ6 ATP 2.41379
59 3TK1 GDP 2.42424
60 1VKJ A3P 2.45614
61 4DP3 NDP 2.46711
62 4DP3 MMV 2.46711
63 1H9G COA MYR 2.46914
64 1NLM UD1 2.47253
65 5YT0 GDP 2.47253
66 5ZB0 TYD 2.52525
67 5ZB0 ADP 2.52525
68 5K5Z ANP 2.54777
69 4ZDJ UTP 2.55537
70 1D2N ANP 2.57353
71 5M7P ADP 2.64317
72 5BN3 ADP 2.64423
73 3HU3 AGS 2.65849
74 5HCN GCP 2.68199
75 4IOK ADP 2.68336
76 2OZE AGS 2.68456
77 3KJS DQ1 2.68714
78 3KJS NAP 2.68714
79 1QHG ATP 2.76243
80 4WBD CIT 2.77264
81 1RKX NAD 2.80112
82 4BFW ZVW 2.83019
83 2VVG ADP 2.85714
84 2QEN ADP 2.85714
85 4R43 GDP 2.8754
86 3NRR D16 2.91262
87 3NRR NAP 2.91262
88 4PJ3 ANP 2.91667
89 1GWN GTP 2.92683
90 3VOI RCB 2.94906
91 2H7C SIA 2.95203
92 5IFS ADP 2.95359
93 2JJK R15 2.95858
94 2W58 ADP 2.9703
95 4LAE NAP 2.99401
96 4LAE 1VM 2.99401
97 6BK3 UDP 2.99786
98 5IRN ADP 3.05556
99 5W75 GDP 3.06122
100 3A1S GDP 3.10078
101 3QDK QDK 3.14685
102 3KJI ADP 3.14961
103 1YQT ADP 3.15985
104 1A8R GTP 3.16742
105 5I34 GDP 3.1746
106 1X6V ADP 3.1746
107 4D81 ADP 3.18021
108 3EC1 GDP 3.25203
109 4UXH T5A 3.26087
110 1M7B GTP 3.26087
111 4NCN GTP 3.28228
112 4KFU ACP 3.30189
113 2WKQ GTP 3.31325
114 5YV5 ADP 3.35821
115 4Z24 FAD 3.37423
116 4E03 ADP 3.39806
117 1X8J A3P 3.4188
118 4M7V NAP 3.42857
119 1Q0H NDP 3.44828
120 1SVM ATP 3.44828
121 1PVN MZP 3.45745
122 4IDN GNP 3.50109
123 1IWE IMP 3.50109
124 5YVT NAI 3.53982
125 1DAK DPU 3.57143
126 1DAK ADP 3.57143
127 5JCP GDP ALF 3.61111
128 2OG2 MLI 3.62117
129 4O0L NDP 3.63636
130 1WUR 8DG 3.63636
131 2DPY ADP 3.65297
132 1A4R GDP 3.66492
133 1A4R GNH 3.66492
134 1OIV GDP 3.66492
135 1OIX GDP 3.66492
136 2NUN ADP 3.71517
137 4TTQ ATP 3.72093
138 5AHS COA 3.74065
139 3RG9 NDP 3.75
140 3RG9 WRA 3.75
141 5OSW AE4 3.77358
142 5H7K GDP 3.77834
143 1M7G AV2 3.79147
144 1M7G ADX 3.79147
145 3TM0 ANP 3.80228
146 3TM0 B31 3.80228
147 4R2I ANP 3.80952
148 3FWY ADP 3.82166
149 2ORV 4TA 3.84615
150 1JJV ATP 3.8835
151 1PUJ GNP 3.90071
152 4X1T UDP 3.92157
153 4XB4 45D 3.94737
154 4YDS ATP 3.94737
155 1S8F GDP 3.9548
156 2C6Q NDP 3.9886
157 3CPJ GDP 4.03587
158 3MGB PAP 4.07523
159 1RYD NDP 4.13437
160 1SKQ GDP 4.13793
161 3ITJ CIT 4.14201
162 3Q85 GNP 4.14201
163 1IN4 ADP 4.19162
164 4NON GDP 4.23077
165 4XVU ATP 4.23729
166 2WOJ ADP ALF 4.23729
167 4U9U FAD 4.27046
168 2BEK ATP 4.28016
169 1D2E GDP 4.28212
170 3B9Q MLI 4.30464
171 2ZPA ADP 4.30556
172 4HI0 GDP 4.33071
173 4TMZ GSP 4.34783
174 4DCT GDP 4.38596
175 4OHY ANP 4.40835
176 3T34 GDP 4.44444
177 3IIJ ADP 4.44444
178 5M04 GDP 4.44444
179 4YC7 GNP 4.46194
180 4ZB8 GDS 4.5045
181 6H5E ANP 4.57666
182 2CE7 ADP 4.62185
183 3REF GDP 4.63918
184 1G3Q ADP 4.64135
185 5BXQ GDP 4.72441
186 4V0K GDP 4.73373
187 2YOH WMJ 4.7619
188 2ZCQ B65 4.77816
189 5URY PAM 4.79452
190 1TLL FAD 4.79651
191 6DEF GCP 4.85933
192 5DK4 5BX 4.86322
193 5DK4 ATP 4.86322
194 3AQ4 GDP 4.8913
195 1OCU PIB 4.93827
196 3DEF GDP 4.96183
197 1Q19 SSC 4.97018
198 5FG3 GDP 4.97592
199 2F9L GDP 5.02513
200 1LVG ADP 5.05051
201 3CRZ NAP 5.05837
202 2R42 FPS 5.06329
203 1YTM ATP 5.07519
204 4BQS K2Q 5.11364
205 4BQS ADP 5.11364
206 2NGR GDP 5.12821
207 4PFT MAB 5.14706
208 4R98 GNH 5.16605
209 4LHW GNP 5.17241
210 1NJF AGS 5.2
211 4B47 GDP 5.23416
212 4HUT ATP 5.2356
213 1TAD GDP 5.24691
214 1TAD ALF 5.24691
215 6CS8 F9Y 5.28053
216 2HF9 GSP 5.30973
217 5L3R GCP 5.31561
218 4U00 ADP 5.32787
219 5O2T GSP 5.34759
220 1ION ADP 5.34979
221 3QXC ATP 5.3719
222 3BOS CDP 5.3719
223 1KSH GDP 5.37634
224 5TC4 NAD 5.37975
225 1SVK ALF GDP 5.38244
226 5EXT ADP 5.38462
227 1H74 ADP 5.40541
228 3VO1 FAD 5.41401
229 3KDU NKS 5.41516
230 1NY5 ADP 5.42636
231 3NC9 TR3 5.43131
232 5GOE GDP 5.45024
233 3NOJ PYR 5.46218
234 1ZCB GDP 5.52486
235 3BFV ADP 5.53506
236 3ZQ6 ADP ALF 5.55556
237 1XPJ TLA 5.55556
238 5DHF GNP 5.59441
239 5UWU GNP 5.59441
240 5UWQ GNP 5.59441
241 5DIF GNP 5.59441
242 5UWP GNP 5.59441
243 5UWJ GNP 5.59441
244 5YSQ INS 5.59441
245 5UWH GNP 5.59441
246 5UWT GNP 5.59441
247 5UWI GNP 5.59441
248 5UWR GNP 5.59441
249 4LC1 GDP 5.63798
250 3VX3 ADP 5.64516
251 3AB3 GDP 5.69106
252 3NKV GNP 5.71429
253 4HAT GNP 5.71429
254 1AQU A3P 5.72391
255 2D7D ADP 5.74887
256 4RD0 GDP 5.78313
257 1FQJ GDP 5.84615
258 1FQK GDP 5.84615
259 5SZH GNP 5.88235
260 1R2Q GNP 5.88235
261 2BL9 NDP 5.88235
262 1G7S GDP 5.89226
263 1XMV ADP 5.89888
264 1GRN GDP 5.91133
265 1FNN ADP 5.9126
266 3RAB GNP 5.91716
267 3CX8 GSP 5.91716
268 4TL6 ANP 5.92885
269 2QV7 ADP 5.93472
270 3HBF MYC 5.94714
271 3HBF UDP 5.94714
272 1Q9I TEO 5.95447
273 1Q9I FAD 5.95447
274 3COB ADP 5.96206
275 4XGU ADP 5.97222
276 4PPF FLC 6
277 2ZR9 DTP 6.01719
278 3Q72 GNP 6.0241
279 1BH2 GSP 6.03175
280 2Z5F A3P 6.04027
281 1TQ4 GDP 6.05327
282 4U5X GNP 6.17978
283 2XTZ GSP 6.21469
284 2EVL GAL SPH EIC 6.2201
285 2CIG 1DG 6.28931
286 3P4X ADP 6.2954
287 1OFH ADP 6.32184
288 2CBZ ATP 6.32911
289 3KTA AP5 6.35838
290 2XTN GTP 6.41026
291 2FNA ADP 6.44258
292 3RWO GDP 6.48649
293 5TB5 GDP 6.48649
294 5N69 ADP 6.53266
295 4ZNL BEF ADP 6.56934
296 1MKY GDP 6.60592
297 4M9Q GNP 6.60793
298 3T64 DU3 6.62983
299 3WXM GTP 6.64894
300 4WOP CTP 6.66667
301 3E70 GDP 6.70732
302 4KVA GTP 6.79612
303 4GOJ GNP 6.87831
304 6FA4 GNP 6.93642
305 1E2K TMC 6.94864
306 5VGR GDP 6.96056
307 1HTW ADP 6.96203
308 2GCN GDP 6.96517
309 2GCO GNP 6.96517
310 1XEX ATP 6.97674
311 2PZE ATP 6.9869
312 3DZD ADP 7.06522
313 2J0V GDP 7.07547
314 2BKK ADP 7.10059
315 1CS4 GSP 7.1066
316 1SQ5 ADP 7.14286
317 1FZQ GDP 7.18232
318 1P72 ADP 7.18563
319 6BVK GNP 7.18563
320 6D5J GNP 7.18563
321 6D5H GNP 7.18563
322 6BVI GNP 7.18563
323 6D5E GNP 7.18563
324 6D59 GNP 7.18563
325 6BVJ GNP 7.18563
326 6D56 GNP 7.18563
327 6BVM GNP 7.18563
328 6D5L GNP 7.18563
329 6BVL GNP 7.18563
330 2D2F ADP 7.2
331 2WJH GDP 7.22892
332 1P9B GDP 7.23982
333 1YZG GDP 7.26257
334 2Y8E GNP 7.26257
335 2H92 C5P 7.30594
336 3GJX GTP 7.36111
337 1WA5 GTP 7.38636
338 1RYH GNP 7.38916
339 1H65 GDP 7.40741
340 4ZKD GDP 7.41483
341 6AU6 GDP 7.42706
342 3QBT GNP 7.47126
343 3TNF GNP 7.47126
344 2WMO GTP 7.47664
345 3SBD GNP 7.48663
346 2WIC GNP 7.49064
347 5E5U MLI 7.53769
348 1RJ9 GCP 7.56579
349 6BC0 GSP 7.56757
350 5HPY GDP 7.56757
351 4D0N GDP 7.56757
352 6BCA GSP 7.56757
353 3LXR GDP 7.56757
354 3U31 NAD 7.58621
355 1TU3 GNP 7.59494
356 1GOJ ADP 7.60563
357 1KMQ GNP 7.6087
358 2IYL GDP 7.74648
359 1E96 GTP 7.8125
360 1I4D GDP 7.8125
361 4XSH GSP 7.82123
362 5JCZ GDP 7.82123
363 3LN0 52B 7.83646
364 1TX4 ALF GDP 7.9096
365 4LX0 BEF GDP 7.9096
366 1WF3 GNP 7.97342
367 2WJG GDP 7.97872
368 3DFR NDP 8.02469
369 1MH1 GNP 8.06452
370 4RZ3 ADP 8.13559
371 1G4U GDP 8.15217
372 2OFW ADX 8.17308
373 2FJU GSP 8.42697
374 2X77 GDP 8.46561
375 5L3W GDP 8.49673
376 1HE1 GDP 8.52273
377 3WYA GDP 8.52535
378 4ITR GDP 8.5443
379 5UPK GNP 8.64865
380 1W4R TTP 8.71795
381 4DDY DN6 8.74525
382 3S2U UD1 8.76712
383 5L3S GNP 8.78378
384 1GXU 2HP 8.79121
385 4G86 BNT 8.80282
386 3W5J GDP 8.82353
387 4ITM ATP 8.88889
388 5JE0 AZ8 8.90688
389 5JE0 SAH 8.90688
390 2OBM ADP 8.93372
391 1Z0F GDP 8.93855
392 5EP2 AZU 8.98438
393 2C78 GNP 9.1358
394 2C77 GNP 9.1358
395 1IHU ADP 9.16808
396 1IHU AF3 9.16808
397 3GJ7 GDP 9.18367
398 2CK3 ADP 9.19118
399 2CK3 ANP 9.19118
400 1W0J ADP BEF 9.19118
401 1W0J ADP 9.19118
402 4J0Q GDP 9.23787
403 1W7J ADP BEF 9.27152
404 1XNG DND 9.32836
405 4V03 ADP 9.33852
406 1KY3 GDP 9.34066
407 5EE5 GTP 9.38967
408 1G16 GDP 9.41177
409 3IO3 ADP 9.48276
410 2PEZ GGZ 9.49721
411 2PEZ DAT 9.49721
412 1UWZ THU 9.55882
413 2G77 GDP 9.59596
414 5W7Q GDP 9.65147
415 4NTO 1PW 9.66184
416 2ACV UDP 9.71922
417 2AG5 NAD 9.7561
418 5NM7 GLY 9.77444
419 4ZI2 GNP 9.77444
420 3GJ8 GDP 9.78261
421 2ZFI ADP 9.83607
422 4TMK T5A 9.85915
423 4DID GDP 9.86842
424 5W76 GDP 9.87013
425 1D5C GDP 9.87654
426 4M8E 29V 9.95671
427 3A4M ADP 10
428 1Z06 GNP 10.0529
429 1NF3 GNP 10.1562
430 4QVX 3CQ 10.1796
431 4P3Y GDP 10.4061
432 4G5G GDP 10.4061
433 4PC3 GDP 10.4061
434 5JBQ GDP 10.4061
435 3U6K GDP 10.4061
436 3U6B GDP 10.4061
437 1D8T GDP 10.4326
438 2BVN GNP 10.4326
439 5MVR ADP 10.4938
440 1VHT BA3 10.5505
441 5KUT GDP 10.582
442 1XTT U5P 10.6481
443 1SVI GDP 10.7692
444 2D7C GTP 10.7784
445 3EZ2 ADP 10.804
446 5DI3 GNP 10.8108
447 2HV8 GTP 10.9375
448 2PID YSA 10.9551
449 6BCB GSP 10.9589
450 4XOI GTP 11.1111
451 5B4B LP5 11.2903
452 2ODE ALF GDP 11.3475
453 5OEC GDP 11.4754
454 2A5J GDP 11.5183
455 1CXZ GSP 11.6279
456 2O0J ADP 11.6883
457 3MJH GTP 11.7647
458 3H4S ADP 11.8519
459 2D37 NAD 11.9318
460 2D37 FMN 11.9318
461 5IRR GSP 12.013
462 2V7Q ADP 12.1212
463 2V7Q ATP 12.1212
464 2EFE GNH 12.1547
465 1EZV SMA 12.1622
466 5O74 GDP 12.1827
467 1KQN NAD 12.1864
468 1YRB GDP 12.2137
469 4P4T GDP 12.2222
470 3WYF GTP 12.3288
471 2W2X GSP 12.4324
472 1VG9 GDP 12.4324
473 1VG1 GDP 12.4324
474 2P4Y C03 12.6354
475 3TKL GTP 12.7551
476 3FUR Z12 12.8676
477 1OW3 GDP 12.9534
478 3TBK ANP 12.973
479 4KBS PX2 13.0233
480 1KO8 6PG 13.1429
481 1M2O GNP 13.1579
482 4GBM A3P 13.3127
483 1UPT GTP 13.3333
484 1JJ7 ADP 13.4615
485 1FP6 ADP 13.4948
486 4XTR ATP 13.5135
487 4XTR ADP 13.5135
488 2FH5 GTP 13.5135
489 1BG2 ADP 13.5385
490 5H67 ATP 13.5678
491 3IA4 NDP 13.5802
492 3N5C GDP 13.5802
493 3KUD GDP 13.5802
494 1YVD GNP 13.6095
495 4KAX GTP 13.6095
496 3SFV GDP 13.8122
497 1ZJ6 G3D 13.9037
498 2W83 GTP 13.9394
499 2A5F GTP 13.9896
500 2ZEJ GDP 14.1304
501 1D1G NDP 14.2857
502 4GOX A3P 14.377
503 1Z08 GNP 14.7059
504 3LRE ADP 14.9296
505 2GJ8 ALF GDP 15.1163
506 3DOE GTP 15.1515
507 2IBZ SMA 15.1515
508 3CNL GNP 15.2672
509 3CXH SMA 15.3846
510 5J1J ANP 15.4386
511 1GP2 GDP 15.493
512 6CRK GDP 15.493
513 5XKT GNP 15.5
514 1Z0A GDP 15.5172
515 1R4A GNP 15.6863
516 2EW1 GNP 15.9204
517 2QTV GNP 16.3265
518 3PQC GDP 16.4103
519 4K81 GTP 16.6667
520 1Y63 ADP 16.8478
521 3T12 GDP ALF 16.9118
522 3Q9L ATP 16.9231
523 3CH5 GDP 17.3077
524 2FZH DH1 17.4757
525 5WL1 D3D 18.1818
526 5WL1 CUY 18.1818
527 2BCG GDP 18.4466
528 2KIN ADP 18.4874
529 1GUA GNP 18.5629
530 1G6H ADP 18.677
531 1G7C 5GP 19.1489
532 1DS6 GDP 19.4444
533 6B4K ANP 20
534 1EK0 GNP 20
535 3QF7 ANP 20
536 2BME GNP 20.4301
537 1YZN GNP 20.5405
538 1NRJ GTP 20.6422
539 1U8Z GDP 20.8333
540 3ZIA ADP 21.0145
541 4BAS GNP 21.1055
542 1ZD9 GDP 21.2766
543 2HCJ GDP 21.6216
544 2QZ4 ADP 21.7557
545 6AIC AMP 21.9626
546 1MR3 G3D 22.0994
547 5XC5 GTP 22.1591
548 1KK8 BEF ADP 22.7273
549 4YLG GDP 23.1214
550 5UWW GNP 23.8095
551 5DI9 GNP 23.8095
552 1RE0 GDP 24.3902
553 1S9D GDP 24.3902
554 1QHH ATP 24.5509
555 2J59 GTP 24.6988
556 1O3Y GTP 24.6988
557 1Z0K GTP 25
558 2OM2 GDP 25
559 4C4P GNP 25.2336
560 2CJW GDP 26.0417
561 5KDO GDP 27.027
562 1GOT GDP 27.3973
563 2ZTS ADP 27.49
564 3B5J 12D 27.9835
565 3WY9 GDP 28.125
566 3T5G GDP 29.8343
567 6BSX GDP 30.3371
568 6BSX E7S 30.3371
569 3ZS9 ADP ALF 31.5789
570 4D0G GTP 31.8841
571 4A4Z ANP 31.9444
572 1J2J GTP 33.3333
573 2Y65 ADP 35
574 3MWL 8OX 37.6812
575 6CIT GNP 38.0952
576 6C90 ADP 39.1667
577 4KBF AMP 41.3699
578 5UWO GNP 45
579 5UWS GNP 45.4545
580 5LB3 ADP 46.5169
581 1Y3A GDP 50
Pocket No.: 2; Query (leader) PDB : 2ZJ5; Ligand: ADP; Similar sites found with APoc: 9
This union binding pocket(no: 2) in the query (biounit: 2zj5.bio2) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 4CDN FAD 1.65975
2 4XF6 ADP 2.5641
3 4XF6 LIP 2.5641
4 4XF6 INS 2.5641
5 1F5N GNP 4.89865
6 1M4I COA 9.39227
7 1M4I KAN 9.39227
8 3M1I GTP 12.3288
9 3B8I OXL 17.77
Pocket No.: 3; Query (leader) PDB : 2ZJ5; Ligand: ADP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 2zj5.bio2) has 13 residues
No: Leader PDB Ligand Sequence Similarity
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