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Receptor
PDB id Resolution Class Description Source Keywords
2ZFU 2 Å EC: 2.-.-.- STRUCTURE OF THE METHYLTRANSFERASE-LIKE DOMAIN OF NUCLEOMETH HOMO SAPIENS NUCLEOLAR PROTEIN SAM-BINDING PROTEIN PROTEIN STRUCTURE NPHOSPHOPROTEIN NUCLEAR PROTEIN
Ref.: EPIGENETIC CONTROL OF RDNA LOCI IN RESPONSE TO INTR ENERGY STATUS CELL(CAMBRIDGE,MASS.) V. 133 627 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAH A:900;
B:900;
Valid;
Valid;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2ZFU 2 Å EC: 2.-.-.- STRUCTURE OF THE METHYLTRANSFERASE-LIKE DOMAIN OF NUCLEOMETH HOMO SAPIENS NUCLEOLAR PROTEIN SAM-BINDING PROTEIN PROTEIN STRUCTURE NPHOSPHOPROTEIN NUCLEAR PROTEIN
Ref.: EPIGENETIC CONTROL OF RDNA LOCI IN RESPONSE TO INTR ENERGY STATUS CELL(CAMBRIDGE,MASS.) V. 133 627 2008
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 269 families.
1 2ZFU - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 237 families.
1 2ZFU - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 2ZFU - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2ZFU; Ligand: SAH; Similar sites found with APoc: 522
This union binding pocket(no: 1) in the query (biounit: 2zfu.bio2) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 3Q87 SAM None
2 6F9Q NAD None
3 2YJD YJD None
4 1H0A I3P None
5 3OLL EST None
6 4JWK CTN None
7 1EDO NAP None
8 3KO0 TFP None
9 3C6K MTA 0.930233
10 3C6K SPD 0.930233
11 3QPB URA 0.930233
12 3V1Y NAD 0.930233
13 3L9W AMP 1.39535
14 3L9W GSH 1.39535
15 6EL3 NAP 1.39535
16 4MGD 27N 1.39535
17 4C4A SAH 1.86047
18 3MCT SAH 1.86047
19 3MAG SAH 1.86047
20 5K0A FAD 1.86047
21 5GSN FAD 1.86047
22 5GSN NAP 1.86047
23 5O42 9JW 1.86047
24 5O42 BGC 1.86047
25 5O42 NAD 1.86047
26 5TWB FAD 1.86047
27 5GSN MMZ 1.86047
28 1YQZ FAD 1.86047
29 3KLJ FAD 1.86047
30 1Z3C SA8 2.32558
31 4M73 SAH 2.32558
32 4Y30 49L 2.32558
33 4M73 M72 2.32558
34 3FRH SAH 2.32558
35 5CUQ NSC 2.32558
36 3ELW SAM 2.32558
37 3EVG SAH 2.32558
38 3EVF GTA 2.32558
39 3EVF SAH 2.32558
40 3ELW GP3 2.32558
41 5JJR SAH 2.32558
42 2P41 SAH 2.32558
43 6GKV SAH 2.32558
44 3FPF TNA 2.32558
45 3FPF MTA 2.32558
46 5BUK FAD 2.32558
47 2Q0L FAD 2.32558
48 4RSL FAD 2.32558
49 5J60 FAD 2.32558
50 1ZK7 FAD 2.32558
51 5U8U FAD 2.32558
52 6CI9 NAP 2.32558
53 4JDR FAD 2.32558
54 3TKA SAM 2.32558
55 4Y30 SAH 2.32558
56 1AE1 NAP 2.32558
57 3GU3 SAH 2.7907
58 5KOK SAH 2.7907
59 5MGZ SAH 2.7907
60 5KOK S9T 2.7907
61 5FUB SAH 2.7907
62 5KOK R9T 2.7907
63 3G89 SAM 2.7907
64 1KPH SAH 2.7907
65 1KPG SAH 2.7907
66 3QOX SAH 2.7907
67 5MW4 5JU 2.7907
68 4AZW SAM 2.7907
69 5GVR LMR 2.7907
70 1V59 NAD 2.7907
71 2EWM NAD 2.7907
72 5OFW 9TW 2.7907
73 2ZXI FAD 2.7907
74 5VN0 FAD 2.7907
75 5VN0 NAI 2.7907
76 4AP3 NAP 2.7907
77 4AP3 FAD 2.7907
78 3AQT RCO 2.7907
79 1V59 FAD 2.7907
80 4HXY NDP 2.7907
81 3W54 RNB 2.7907
82 3OA2 NAD 2.7907
83 3GDN FAD 2.7907
84 3EF0 ALF 2.7907
85 6GAS FAD 2.7907
86 3GDN HBX 2.7907
87 3SJ7 NDP 2.7907
88 5JCM NAD 2.7907
89 5JCM FAD 2.7907
90 5JCM ISD 2.7907
91 3ICS FAD 2.7907
92 4IGH FMN 2.7907
93 4IGH 1EA 2.7907
94 4IGH ORO 2.7907
95 1Y7P RIP 2.7907
96 3X0D SAH 3.25581
97 2PWY SAH 3.25581
98 1I1N SAH 3.25581
99 1U2Z SAH 3.25581
100 5FTW SAH 3.25581
101 6D6Y SAH 3.25581
102 4PIO AVI 3.25581
103 4PIO SAH 3.25581
104 6ER9 FAD 3.25581
105 3UCL CYH 3.25581
106 3UCL NAP 3.25581
107 3UCL FAD 3.25581
108 6ER9 NAP 3.25581
109 5I39 FAD 3.25581
110 3E1T FAD 3.25581
111 6H3O FAD 3.25581
112 1GR0 NAD 3.25581
113 5MLR GRQ 3.25581
114 5MLR NAP 3.25581
115 1HDG NAD 3.25581
116 2RGO FAD 3.25581
117 3NKS FAD 3.25581
118 4DMG SAM 3.25581
119 4RPL 3UC 3.25581
120 4RPL FAD 3.25581
121 4CNK FAD 3.25581
122 2Q1S NAI 3.25581
123 1IY8 NAD 3.25581
124 5NM7 GLY 3.25581
125 4NTC FAD 3.25581
126 3K7M FAD 3.25581
127 3CIF NAD 3.25581
128 3QV1 NAD 3.65854
129 3LCC SAH 3.72093
130 5M58 SAH 3.72093
131 6ARJ BW4 3.72093
132 6ARJ SAH 3.72093
133 3I53 SAH 3.72093
134 5DX8 SFG 3.72093
135 1JG3 ADN 3.72093
136 5DXA SFG 3.72093
137 5DX1 SFG 3.72093
138 5DWQ SFG 3.72093
139 5DX0 SFG 3.72093
140 3FUU ADN 3.72093
141 2WPF FAD 3.72093
142 1DL5 SAH 3.72093
143 3HVJ 705 3.72093
144 2NXE SAM 3.72093
145 3TLJ SAH 3.72093
146 2WPF WPF 3.72093
147 2V6G NAP 3.72093
148 3AXB PRO 3.72093
149 3AXB FAD 3.72093
150 3U4C NDP 3.72093
151 2WET FAD 3.72093
152 3LZW NAP 3.72093
153 4WOE 3S5 3.72093
154 3LXD FAD 3.72093
155 3P9C SAH 3.72093
156 4D5G FAD 3.72093
157 4X9M FAD 3.72093
158 4D5G TPP 3.72093
159 5JAQ NAI 3.72093
160 4F06 PHB 3.72093
161 3R9V DXC 3.72093
162 5XNC MTA 3.72093
163 2AE2 NAP 3.72093
164 2AE2 PTO 3.72093
165 2JB2 FAD 3.72093
166 2JB2 PHE 3.72093
167 1KYQ NAD 3.72093
168 1Z45 NAD 3.72093
169 3LZW FAD 3.72093
170 4J36 FAD 3.72093
171 2Q1W NAD 3.72093
172 4NTD FAD 3.72093
173 3EGI ADP 3.8835
174 3KP6 SAL 3.97351
175 5EEH P9P 3.98936
176 5EEH SAH 3.98936
177 4POO SAM 4
178 2EFJ SAH 4.18605
179 2UYQ SAM 4.18605
180 2EG5 SAH 4.18605
181 1KYZ SAH 4.18605
182 2BZG SAH 4.18605
183 1QAN SAH 4.18605
184 2A14 SAH 4.18605
185 5FJN FAD 4.18605
186 5FJN BE2 4.18605
187 1R18 SAH 4.18605
188 1KYZ FER 4.18605
189 1FEC FAD 4.18605
190 2JJQ SAH 4.18605
191 3GEG NAD 4.18605
192 5DF1 NAP 4.18605
193 5DF1 58X 4.18605
194 5BVA FAD 4.18605
195 4YAC NAI 4.18605
196 4YRY NAD 4.18605
197 2GN4 NDP 4.18605
198 2CBZ ATP 4.18605
199 5J7X FAD 4.18605
200 2IID PHE 4.18605
201 2IID FAD 4.18605
202 4YRY FAD 4.18605
203 2IVD FAD 4.18605
204 2VVL FAD 4.18605
205 6F7L FAD 4.18605
206 4REP FAD 4.24242
207 3G5K BB2 4.37158
208 5MTE BB2 4.37956
209 2DPM SAM 4.65116
210 6B92 SAH 4.65116
211 1YXM ADE 4.65116
212 5ZW3 SAH 4.65116
213 2XVE FAD 4.65116
214 6GFK SAH 4.65116
215 6FDF SAH 4.65116
216 2XVF FAD 4.65116
217 3AYI FAD 4.65116
218 3AYI HCI 4.65116
219 1RYI GOA 4.65116
220 1RYI FAD 4.65116
221 1EFV FAD 4.65116
222 4ZCC NAI 4.65116
223 4ZCC FAD 4.65116
224 1EFV AMP 4.65116
225 2CDU FAD 4.65116
226 4IV9 FAD 4.65116
227 4UZI IMD 4.65116
228 6GAR FAD 4.65116
229 4D04 NAP 4.65116
230 4D04 FAD 4.65116
231 4NBU NAI 4.65116
232 3QVP FAD 4.65116
233 5XLX SAH 4.65116
234 2HQM FAD 4.65116
235 1UAY ADN 4.65116
236 2VT3 ATP 4.65116
237 5TS5 FAD 4.65116
238 1NAA 6FA 4.65116
239 1NAA ABL 4.65116
240 4QTU SAM 4.80769
241 1NV8 MEQ 4.92958
242 1NV8 SAM 4.92958
243 5YW5 ADE 5.02793
244 5CLO NS8 5.08475
245 3G2O SAM 5.11628
246 6DUB SAH 5.11628
247 2EJU SAH 5.11628
248 1XDS SAM 5.11628
249 2WA2 SAM 5.11628
250 1NW5 SAM 5.11628
251 3A25 SAM 5.11628
252 1PJS NAD 5.11628
253 3HDY FDA 5.11628
254 3HDY GDU 5.11628
255 4B63 ORN 5.11628
256 4B63 FAD 5.11628
257 4B63 NAP 5.11628
258 3HDY FAD 5.11628
259 4MOP 2H5 5.11628
260 1I8T FAD 5.11628
261 3LTW HLZ 5.11628
262 1UWK NAD 5.11628
263 1UWK URO 5.11628
264 2NVK FAD 5.11628
265 1ZEM NAD 5.11628
266 4YJK URA 5.11628
267 5UAO FAD 5.11628
268 1BXK NAD 5.11628
269 2AQJ TRP 5.11628
270 2AQJ FAD 5.11628
271 5X20 AOT 5.11628
272 5L2R MLA 5.11628
273 4M52 M52 5.15021
274 2A8X FAD 5.17241
275 3GWZ SAH 5.5814
276 3DXY SAM 5.5814
277 3GXO SAH 5.5814
278 3OFK SAH 5.5814
279 4DCM SAM 5.5814
280 3RKR NAP 5.5814
281 4EUE NAI 5.5814
282 1QZZ SAM 5.5814
283 3WGT QSC 5.5814
284 3WGT FAD 5.5814
285 3SSO SAH 5.5814
286 4USR FAD 5.5814
287 1CER NAD 5.5814
288 3UOY NAP 5.5814
289 3UOY FAD 5.5814
290 5N53 8NB 5.64103
291 4CQM NAP 5.7377
292 5HJM MTA 6.04651
293 5MPT SAH 6.04651
294 1JQ3 AAT 6.04651
295 3VSE SAH 6.04651
296 2PX8 SAH 6.04651
297 4XUC SAM 6.04651
298 4XUC 43G 6.04651
299 1E1M NAP 6.04651
300 1E1M FAD 6.04651
301 5EJ2 NAD 6.04651
302 1E6E FAD 6.04651
303 4N49 SAM 6.04651
304 4FWE FAD 6.04651
305 2ZIF SAM 6.04651
306 4PZ6 GMP 6.04651
307 4Z0H NAD 6.04651
308 3WYJ H78 6.04651
309 3CBG SAH 6.04651
310 4J56 FAD 6.14035
311 3FZG SAM 6.5
312 4R6W PC 6.51163
313 4R6W SAH 6.51163
314 5W7K SAH 6.51163
315 2FK8 SAM 6.51163
316 1L1E SAH 6.51163
317 1TPY SAH 6.51163
318 1G55 SAH 6.51163
319 2DTX BMA 6.51163
320 1RSG FAD 6.51163
321 4YAG NAI 6.51163
322 5N0J FAD 6.51163
323 1PN0 FAD 6.51163
324 1PN0 IPH 6.51163
325 3RNM FAD 6.51163
326 5J5Z FAD 6.51163
327 1ELI PYC 6.51163
328 3S5W FAD 6.51163
329 2F5Z FAD 6.51163
330 5HSA FAS 6.51163
331 3CMC NAD 6.51163
332 3GRU AMP 6.77966
333 1Q0S SAH 6.94981
334 3JWH SAH 6.97674
335 5DLY 5D7 6.97674
336 5DLY SAH 6.97674
337 3GCZ SAM 6.97674
338 1JQD SAH 6.97674
339 2AOT SAH 6.97674
340 1JQD HSM 6.97674
341 1YY5 FAD 6.97674
342 3G5S FAD 6.97674
343 2RH4 EMO 6.97674
344 1W6F ISZ 6.97674
345 1NE7 16G 6.97674
346 5UR0 NAD 6.97674
347 2RAB NAD 6.97674
348 2RAB FAD 6.97674
349 4DSG FAD 6.97674
350 4DSG UDP 6.97674
351 2ZWA SAH 7.44186
352 4M38 SAH 7.44186
353 5FA5 MTA 7.44186
354 4X60 SFG 7.44186
355 4X60 3XV 7.44186
356 4GQB 0XU 7.44186
357 4M37 SAH 7.44186
358 4FZV SAM 7.44186
359 1O97 FAD 7.44186
360 1O97 AMP 7.44186
361 1E3W NAD 7.44186
362 1E6W NAD 7.44186
363 3VYW SAM 7.44186
364 4ONQ SFG 7.44186
365 6F97 FAD 7.44186
366 3FPZ AHZ 7.44186
367 1Q9I TEO 7.44186
368 1Q9I FAD 7.44186
369 3O03 NAP 7.44186
370 3CTY FAD 7.83699
371 2YX1 SFG 7.90698
372 1N2X SAM 7.90698
373 1Y8Q ATP 7.90698
374 2XYQ SAH 7.90698
375 4Z24 FAD 7.90698
376 1GPE FAD 7.90698
377 4GUS FAD 8.06452
378 4HSU FAD 8.06452
379 4GUT FAD 8.06452
380 2GAG FAD 8.08081
381 2GAG FOA 8.08081
382 2GAG NAD 8.08081
383 5DM1 SAH 8.37209
384 5DM1 5D7 8.37209
385 3O7W SAM 8.37209
386 5WP4 SAH 8.37209
387 5THY SAH 8.37209
388 3A4T SFG 8.37209
389 5W7R SAH 8.37209
390 5THZ SAH 8.37209
391 5FWA J7C 8.37209
392 5G3U FDA 8.37209
393 5G3U ITW 8.37209
394 5W7R 9Z7 8.37209
395 1YBH FAD 8.37209
396 2YG3 FAD 8.37209
397 4KGD FAD 8.37209
398 5TTJ FAD 8.37209
399 4KGD TDP 8.37209
400 1G0N PHH 8.37209
401 1G0N NDP 8.37209
402 5WP4 PC 8.37209
403 1GXU 2HP 8.79121
404 3TKY SAH 8.83721
405 5E8J SAH 8.83721
406 5E9W SAH 8.83721
407 2PT9 2MH 8.83721
408 2PT9 S4M 8.83721
409 2I7C AAT 8.83721
410 4USQ FAD 8.83721
411 1XG5 NAP 8.83721
412 5L95 AMP 8.83721
413 1G60 SAM 9.30233
414 4YUW S4M 9.30233
415 4YUW 4JU 9.30233
416 5NMX NAP 9.30233
417 1XCL SAH 9.30233
418 5NMX FAD 9.30233
419 3GDH SAH 9.30233
420 5ERG SAM 9.30233
421 2BD0 NAP 9.30233
422 4MIG G3F 9.30233
423 1D4D FAD 9.30233
424 2YVF NAD 9.30233
425 2CUL FAD 9.48276
426 1MFI FHC 9.64912
427 5X62 SAH 9.76744
428 2HZL PYR 9.76744
429 4LH7 1X8 9.76744
430 4LH7 NMN 9.76744
431 2Q7V FAD 9.76744
432 4II2 ATP 9.76744
433 1BC5 SAH 9.76744
434 1P1C SAH 10.0503
435 5W7M SAH 10.2326
436 1RJW ETF 10.2326
437 5GWX SAM 10.2326
438 5GWX SAR 10.2326
439 1REO FAD 10.2326
440 2YLD CMO 10.2362
441 3H8V ATP 10.6164
442 1VE3 SAM 10.6977
443 3NDJ JHZ 10.6977
444 3NDJ SAH 10.6977
445 5YJI 8WO 10.6977
446 5YJI SAH 10.6977
447 2O07 SPD 10.6977
448 2O07 MTA 10.6977
449 5JCA FAD 10.6977
450 5JCA NDP 10.6977
451 3A27 SAM 10.6977
452 2R4J 13P 10.6977
453 2R4J FAD 10.6977
454 1YQT ADP 10.6977
455 5YV5 ADP 10.6977
456 5ICE SAH 11.1628
457 5ICE 2H4 11.1628
458 5E1M PRO PRO LYS ARG ILE ALA 11.1628
459 5E1M SAH 11.1628
460 3DUW SAH 11.1628
461 5WGR FAD 11.1628
462 2GV8 FAD 11.1628
463 1VQW FAD 11.1628
464 1ZQ9 SAM 11.1628
465 2GVC FAD 11.1628
466 4BLW AMP 11.6279
467 4BLW SAH 11.6279
468 2VDV SAM 12.093
469 5OCA 9QZ 12.1849
470 1EJ0 SAM 12.2222
471 1IM8 SAI 12.5581
472 3MB5 SAM 12.5581
473 3C3Y SAH 12.5581
474 2JHP SAH 12.5581
475 1WY7 SAH 12.5604
476 4OBW SAM 13.0233
477 5BJX NAD 13.0233
478 5BJX UDP 13.0233
479 4YNU LGC 13.0233
480 4YNU FAD 13.0233
481 1RJD SAM 13.4884
482 1U7T TDT 13.4884
483 3GD4 FAD 13.4884
484 3GD4 NAD 13.4884
485 1BZL GCG 14.4186
486 3S1S SAH 14.4186
487 1BZL FAD 14.4186
488 3RV5 DXC 14.6067
489 2PXX SAH 14.8837
490 4A6D SAM 14.8837
491 1GZ6 NAI 14.8837
492 1N13 AG2 15.0442
493 2QQC AG2 15.1786
494 1ZBQ NAD 15.3488
495 4Y9D NAI 15.814
496 2XVM SAH 16.0804
497 6BR8 PGV 16.2791
498 3LAD FAD 16.7442
499 5YF1 SFG 17.6744
500 5YF1 8V0 17.6744
501 4TM3 FAD 18.6047
502 3BGD SAH 19.0698
503 3BGD PM6 19.0698
504 2GMH FAD 19.0698
505 5WP5 SAH 19.5349
506 3QFA FAD 19.8276
507 3PT9 SAH 20
508 4IWN GEK 21.3953
509 6BQ6 TER 21.8605
510 2OBF F83 21.8605
511 2OBF SAH 21.8605
512 3AD8 FAD 22.2222
513 3AD8 PYC 22.2222
514 4OGQ 7PH 23.125
515 3DMH SAM 24.186
516 3DMH GMP 24.186
517 3VC1 SAH 25.5814
518 3VC1 GST 25.5814
519 4RZB NFQ 26.0465
520 1WG8 SAM 28.8372
521 4D7E FAD 28.8372
522 1LSS NAD 38.5714
Pocket No.: 2; Query (leader) PDB : 2ZFU; Ligand: SAH; Similar sites found with APoc: 92
This union binding pocket(no: 2) in the query (biounit: 2zfu.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 6DNT NAD None
2 3UU7 2OH 1.39535
3 4NBW NAD 1.39535
4 2V57 PRL 1.57895
5 3HP9 CF1 1.86047
6 4BV6 FAD 2.32558
7 1F8G NAD 2.32558
8 3PPQ CHT 2.7907
9 5OC1 FAD 2.7907
10 3ICR FAD 2.7907
11 1XHC FAD 2.7907
12 4RF2 NAP 2.7907
13 2XRH NIO 3
14 1EJH M7G 3.15789
15 5XWV NDP 3.25581
16 5XWV 8H6 3.25581
17 1OC2 NAD 3.25581
18 1OC2 TDX 3.25581
19 5THQ NDP 3.25581
20 3BJE URA 3.25581
21 5AZC PGT 3.25581
22 2JAH NDP 3.25581
23 3LU1 NAD 3.2967
24 4HA6 FAD 3.72093
25 4J36 1HR 3.72093
26 4FN4 NAD 3.72093
27 2Z3Y F2N 3.72093
28 3V1U NAD 3.72093
29 1MO9 KPC 4.18605
30 1MO9 FAD 4.18605
31 2CFC KPC 4.18605
32 1COY FAD 4.18605
33 1COY AND 4.18605
34 2VVM FAD 4.18605
35 1H82 FAD 4.18605
36 1H82 GZZ 4.18605
37 4OUJ LBT 4.18605
38 3SJU NDP 4.18605
39 2CFC NAD 4.18605
40 2YVK MRU 4.18605
41 3ZNN 4WL 4.65116
42 3ZNN FAD 4.65116
43 1X87 NAD 4.65116
44 5M90 JIF 5.11628
45 5WL1 CUY 5.11628
46 5Z2L NDP 5.11628
47 5C9J DAO 5.11628
48 4M52 FAD 5.15021
49 3AB1 FAD 5.5814
50 6EQS BV8 5.5814
51 2WSB NAD 6.04651
52 3WDM ADN 6.04651
53 4USI AKG 6.49351
54 5EB4 FAD 6.51163
55 1JNR FAD 6.51163
56 2JAP NDP 6.51163
57 5K7U SAM 6.51163
58 2G3F IZC 6.97674
59 3X0V FAD 6.97674
60 2QCX PF1 7.44186
61 1T0S BML 8.83721
62 3NTD FAD 9.30233
63 3NT6 FAD 9.30233
64 3NTA FAD 9.30233
65 4YSX FAD 9.61539
66 5OJ7 AR6 9.76744
67 6FP4 FAD 9.76744
68 6FP4 E1T 9.76744
69 3QWI NAP 9.76744
70 2C5A GDC 10.2326
71 2C5A NAD 10.2326
72 4MO2 FAD 10.6977
73 4MO2 FDA 10.6977
74 1ORR NAD 10.6977
75 5GWT NAD 11.1628
76 5GWT SIN 11.1628
77 4BUZ OAD 11.6279
78 4BUZ OCZ 11.6279
79 4BUZ NAD 11.6279
80 5LX9 OLB 12.093
81 1SB8 NAD 12.5581
82 1SB8 UD2 12.5581
83 1Q7B NAP 13.4884
84 3CGB FAD 13.9535
85 4YKG FAD 15.3488
86 4YKG NAD 15.3488
87 2BP1 FLC 15.3488
88 3LGG CFE 17.6744
89 1QO8 FAD 19.5349
90 3AD8 NAD 22.2222
91 1GY8 NAD 23.7209
92 2BO4 FLC 28.8372
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