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Receptor
PDB id Resolution Class Description Source Keywords
2ZB7 1.8 Å EC: 1.3.1.48 CRYSTAL STRUCTURE OF HUMAN 15-KETOPROSTAGLANDIN DELTA-13- REDUCTASE IN COMPLEX WITH NADPH AND NICOTINAMIDE HOMO SAPIENS ROSSMANN FOLD ALTERNATIVE SPLICING CYTOPLASM NADP OXIDOREDUCTASE
Ref.: STRUCTURAL BASIS FOR CATALYTIC AND INHIBITORY MECHANISMS OF HUMAN PROSTAGLANDIN REDUCTASE PTGR2. STRUCTURE V. 16 1714 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NCA A:901;
Valid;
none;
submit data
122.125 C6 H6 N2 O c1cc(...
NDP A:900;
Valid;
none;
submit data
745.421 C21 H30 N7 O17 P3 c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2ZB4 1.63 Å EC: 1.3.1.48 CRYSTAL STRUCTURE OF HUMAN 15-KETOPROSTAGLANDIN DELTA-13- REDUCTASE IN COMPLEX WITH NADP AND 15-KETO-PGE2 HOMO SAPIENS ROSSMANN FOLD ALTERNATIVE SPLICING CYTOPLASM NADP OXIDOREDUCTASE
Ref.: STRUCTURAL BASIS FOR CATALYTIC AND INHIBITORY MECHANISMS OF HUMAN PROSTAGLANDIN REDUCTASE PTGR2. STRUCTURE V. 16 1714 2008
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2ZB7 - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
2 2ZB8 - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
3 2ZB4 - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2ZB7 - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
2 2ZB8 - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
3 2ZB4 - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
4 2ZB3 - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2ZB7 - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
2 2ZB8 - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
3 2ZB4 - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
4 2ZB3 - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
5 4B7X - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
6 1V3V - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
7 1V3T - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
8 2DM6 ic50 = 97.9 uM IMN C19 H16 Cl N O4 Cc1c(c2cc(....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NCA; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 NCA 1 1
2 UNU 0.433333 0.666667
3 0ON 0.428571 0.769231
4 3AB 0.411765 0.6
Ligand no: 2; Ligand: NDP; Similar ligands found: 172
No: Ligand ECFP6 Tc MDL keys Tc
1 NDP 1 1
2 0WD 0.827273 1
3 NAI 0.803738 0.986842
4 NMN AMP PO4 0.794643 0.948052
5 NPW 0.692308 0.962025
6 NZQ 0.686441 0.987013
7 1DG 0.68 1
8 DG1 0.68 1
9 A2R 0.650943 0.909091
10 A22 0.64486 0.934211
11 TXP 0.644628 0.924051
12 ATR 0.640777 0.894737
13 NA7 0.636364 0.886076
14 XNP 0.620968 0.949367
15 AP0 0.598361 0.948718
16 A2P 0.598039 0.881579
17 NJP 0.574803 0.923077
18 25L 0.550847 0.934211
19 ODP 0.550388 0.936709
20 NAX 0.544 0.949367
21 25A 0.53913 0.921053
22 80F 0.537879 0.914634
23 2AM 0.529412 0.87013
24 6V0 0.519685 0.974026
25 NAP 0.514493 0.922078
26 7L1 0.507143 0.763441
27 EAD 0.507143 0.949367
28 A2D 0.504673 0.921053
29 TXE 0.503876 0.935897
30 NA0 0.496454 0.910256
31 TXD 0.496124 0.911392
32 SAP 0.495575 0.875
33 AGS 0.495575 0.875
34 P1H 0.493056 0.925926
35 CO7 0.489796 0.791209
36 TAP 0.489362 0.864198
37 PAP 0.482456 0.907895
38 BA3 0.481818 0.921053
39 NAJ PZO 0.478261 0.924051
40 ATP 0.477876 0.921053
41 HEJ 0.477876 0.921053
42 B4P 0.477477 0.921053
43 AP5 0.477477 0.921053
44 ADP 0.477477 0.921053
45 OAD 0.47541 0.897436
46 AR6 0.473684 0.896104
47 AQP 0.473684 0.921053
48 5FA 0.473684 0.921053
49 APR 0.473684 0.896104
50 AN2 0.473214 0.909091
51 3OD 0.467742 0.897436
52 50T 0.464912 0.884615
53 NAJ PYZ 0.464789 0.879518
54 9X8 0.463415 0.851852
55 PO4 PO4 A A A A PO4 0.463415 0.857143
56 V3L 0.461538 0.896104
57 2A5 0.46087 0.85
58 AT4 0.460177 0.886076
59 A1R 0.459016 0.841463
60 4AD 0.459016 0.875
61 ADQ 0.459016 0.897436
62 OVE 0.458716 0.8375
63 OMR 0.458647 0.813953
64 PPS 0.457627 0.811765
65 AD9 0.456897 0.897436
66 CA0 0.45614 0.897436
67 M33 0.45614 0.884615
68 ADJ 0.455882 0.879518
69 A3P 0.455357 0.894737
70 ACP 0.452174 0.897436
71 ENP 0.451613 0.85
72 UP5 0.451128 0.948052
73 SRP 0.45 0.8625
74 ANP 0.449153 0.897436
75 ACQ 0.449153 0.897436
76 PRX 0.448276 0.82716
77 A3R 0.447154 0.841463
78 5AL 0.445378 0.884615
79 7D4 0.443478 0.8375
80 ADX 0.443478 0.811765
81 6YZ 0.438017 0.897436
82 A 0.436364 0.894737
83 AMP 0.436364 0.894737
84 4TC 0.433824 0.924051
85 7D3 0.433628 0.8375
86 DCA 0.433566 0.788889
87 ETB 0.433566 0.797753
88 BIS 0.433071 0.864198
89 1ZZ 0.433071 0.802326
90 00A 0.432 0.864198
91 ATF 0.429752 0.886076
92 DQV 0.428571 0.934211
93 0T1 0.427586 0.788889
94 5SV 0.427419 0.788235
95 8QN 0.427419 0.884615
96 3AM 0.427273 0.857143
97 N01 0.426573 0.884615
98 PR8 0.425197 0.811765
99 LAD 0.425197 0.821429
100 WAQ 0.425197 0.841463
101 DTP 0.425 0.8375
102 AMO 0.424 0.886076
103 PAJ 0.424 0.843373
104 APC 0.423729 0.886076
105 UPA 0.423358 0.935897
106 48N 0.422222 0.853659
107 FYA 0.421875 0.860759
108 PTJ 0.421875 0.853659
109 CNA 0.421429 0.910256
110 PUA 0.42069 0.9125
111 DND 0.419118 0.910256
112 NXX 0.419118 0.910256
113 AV2 0.418033 0.848101
114 COA 0.417808 0.788889
115 3UK 0.417323 0.897436
116 OOB 0.416 0.909091
117 IVC 0.415584 0.78022
118 DAT 0.415254 0.8375
119 NDO 0.414966 0.897436
120 139 0.414286 0.901235
121 B5V 0.414062 0.886076
122 T99 0.413223 0.886076
123 TAT 0.413223 0.886076
124 3AT 0.413223 0.896104
125 YLB 0.413043 0.784091
126 62F 0.4125 0.823529
127 ABM 0.412281 0.848101
128 B5M 0.412214 0.875
129 YAP 0.412214 0.875
130 YLP 0.411765 0.784091
131 NB8 0.410853 0.853659
132 ME8 0.410853 0.802326
133 SON 0.410256 0.886076
134 DLL 0.409449 0.909091
135 AHX 0.409449 0.853659
136 CAO 0.409396 0.763441
137 30N 0.409396 0.72449
138 AMX 0.409396 0.797753
139 COS 0.409396 0.771739
140 7D5 0.409091 0.8125
141 4UW 0.408759 0.9125
142 F2R 0.408451 0.825581
143 APX 0.407692 0.841463
144 SRA 0.40708 0.85
145 CMX 0.406667 0.788889
146 SCO 0.406667 0.788889
147 TYM 0.405797 0.886076
148 COD 0.405594 0.777778
149 CA6 0.405229 0.70297
150 OXK 0.405229 0.771739
151 AP2 0.405172 0.886076
152 A12 0.405172 0.886076
153 9SN 0.40458 0.853659
154 LAQ 0.404412 0.802326
155 T5A 0.404255 0.914634
156 FAM 0.403974 0.771739
157 ACO 0.403974 0.763441
158 FCX 0.403974 0.763441
159 VO4 ADP 0.403226 0.860759
160 ADP VO4 0.403226 0.860759
161 YLC 0.402878 0.823529
162 1VU 0.402597 0.763441
163 B5Y 0.401515 0.875
164 FA5 0.401515 0.886076
165 HAX 0.401316 0.771739
166 AR6 AR6 0.4 0.871795
167 CAJ 0.4 0.771739
168 AFH 0.4 0.843373
169 APU 0.4 0.923077
170 A U 0.4 0.898734
171 TXA 0.4 0.886076
172 4UU 0.4 0.948052
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2ZB4; Ligand: 5OP; Similar sites found with APoc: 310
This union binding pocket(no: 1) in the query (biounit: 2zb4.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
1 3I6B KDO None
2 2WCV FUC None
3 3DLS ADP 1.49254
4 6MDE MEV 1.65016
5 5YEC ATP 1.68067
6 1GQ2 NAP 1.68067
7 5TSU CYS 1.68067
8 1GR0 NAD 1.68067
9 6APL C5P 1.68067
10 1LLU NAD 1.75439
11 4MP8 MLI 1.76991
12 4MP8 NAD 1.76991
13 4BVA NDP 1.79104
14 4BVA T3 1.79104
15 4E5N NAD 1.81818
16 2PK3 A2R 1.86916
17 5X20 NAD 1.92308
18 4D3F NAP 1.93548
19 1D1T NAD 1.96078
20 1CDO NAD 1.96078
21 5ZIC BMA Z4Y NAG 1.96078
22 4OOE NDP 1.96078
23 2HIM ASP 1.96078
24 2VHW NAI 1.96078
25 1VI2 NAD 2
26 5UR0 NAD 2.00573
27 2HW1 FRU 2.01342
28 2B4R AES 2.02899
29 2B4R NAD 2.02899
30 5GLN XYP XYP XYP 2.03488
31 1WP4 NDP 2.07612
32 1NPD NAD 2.08333
33 4XB2 NDP 2.08955
34 4XB2 HSE 2.08955
35 5U5N NAD 2.15054
36 2A92 NAI 2.18069
37 4A0S NAP 2.2409
38 2CDU ADP 2.2409
39 1LTH NAD 2.2409
40 1E3I CXF 2.2409
41 1O0S NAI 2.2409
42 2B5W NAP 2.2409
43 5E58 CPZ 2.2409
44 6F3N ADN 2.2409
45 6F3M NAD 2.2409
46 6F3N NAD 2.2409
47 3ABI NAD 2.2409
48 1BXG NAD 2.24719
49 3OND NAD 2.2541
50 3OND ADN 2.2541
51 1I36 NAP 2.27273
52 5Z20 NAI 2.31884
53 5YU3 NAD 2.32558
54 5YU3 PRO 2.32558
55 1Z82 NDP 2.38806
56 5OCM NAP 2.4055
57 2F1K NAP 2.50896
58 6BII NAP 2.52101
59 4IYO NAK 2.52101
60 1KOL NAD 2.52101
61 2JLR ANP 2.52101
62 2NAD NAD 2.52101
63 2GSD NAD 2.52101
64 1KYQ NAD 2.55474
65 5KKA 6V0 2.5641
66 2Q0L NAP 2.57235
67 5A04 NDP 2.65487
68 5A04 BGC 2.65487
69 5TZO 7V7 2.65957
70 4JK3 NAD 2.7027
71 4J4H NAI 2.7027
72 4J4H 1J1 2.7027
73 9LDT NAD 2.71084
74 9LDB NAD 2.71084
75 1B8U NAD 2.73556
76 1B8U OAA 2.73556
77 3L9W AMP 2.80112
78 5M67 NAD 2.80112
79 5M67 ADE 2.80112
80 5M67 3D1 2.80112
81 1GZ4 ATP 2.80112
82 3X01 AMP 2.80112
83 6A3J NAI 2.80112
84 5ZZ6 ADP 2.88462
85 5ZZ6 NAD 2.88462
86 1DCP HBI 2.88462
87 1DRV A3D 2.9304
88 5A1T NAI 2.93255
89 5A1T OXM 2.93255
90 3B1J NAD 2.94985
91 3B20 NAD 2.94985
92 5D4V SAH 2.98507
93 3KB6 NAD 2.99401
94 5N6C NAD 3
95 1J49 NAD 3.003
96 5NUF NAD 3.01205
97 5NUE NAD 3.01205
98 4ZVV GN0 3.01205
99 4ZVV NAD 3.01205
100 1LDM NAD 3.03951
101 2AG8 NAP 3.04183
102 1VM6 NAD 3.07018
103 4ARE FLC 3.08123
104 3CIF NAD 3.08123
105 4ZGS NAD 3.08123
106 1HKU NAD 3.08123
107 3CIF G3H 3.08123
108 1J5P NAD 3.16206
109 1LDN NAD 3.16456
110 1Q8S MAN MMA 3.1746
111 2PHX MAN MAN 3.1746
112 1Q8Q MAN MMA 3.1746
113 6BJO DUY 3.2
114 4Y9D NAI 3.27869
115 5JE8 NAD 3.31126
116 1NYT NAP 3.32103
117 4PLT NAI 3.32326
118 4PLT OXM 3.32326
119 5H81 NAP 3.36134
120 1O6Z NAD 3.36134
121 1F8G NAD 3.36134
122 5FI3 NAP 3.36134
123 1PJS NAD 3.36134
124 4BE9 7P9 3.36134
125 2GZ3 NAP 3.36134
126 1T26 GBD 3.41615
127 1T26 NAI 3.41615
128 3I7S PYR 3.42466
129 1ZEM NAD 3.43511
130 3TWO NDP 3.44828
131 5ZI2 NAD 3.47826
132 1DQN IMU 3.47826
133 5ZI2 ADP 3.47826
134 4Z3E GAL NGA GLA BGC GAL 3.53535
135 2Q46 NAP 3.55731
136 1HYH NAD 3.55987
137 5CGE 51F 3.61011
138 1E5Q NDP 3.64146
139 3NJ4 AFX 3.64146
140 3NJ4 NAD 3.64146
141 2D2I NAP 3.64146
142 6C4T NA7 3.64146
143 5GZ6 NDP 3.68098
144 5GZ6 7C3 3.68098
145 3GFB NAD 3.71429
146 2JL1 NAP 3.83275
147 4MDH NAD 3.89222
148 5MDH NAD 3.9039
149 2DFV NAD 3.92157
150 5VKT NAP 3.92157
151 2VYN NAD 3.92157
152 1CY2 TMP 3.92157
153 5LD5 NAD 3.92157
154 5DN9 NAD 3.92157
155 2HK9 ATR 4
156 1X7D NAD 4
157 2HK9 NAP 4
158 1X7D ORN 4
159 1P77 ATR 4.04412
160 4PLG OXM 4.19162
161 4PLG NAI 4.19162
162 5AOV NAP 4.20168
163 1V8B NAD 4.20168
164 4DPL NAP 4.20168
165 5NBW 8SK 4.20561
166 1SOW NAD 4.26829
167 1LSS NAD 4.28571
168 2JK0 ASP 4.30769
169 4XZ3 COA 4.34783
170 5NGL NOJ BGC 4.48179
171 2ZJ1 NAD 4.48179
172 2ZJ1 ARJ 4.48179
173 4Z0H NAD 4.48179
174 1OFZ FUC 4.48718
175 1OFZ FUL 4.48718
176 2DBZ NAP 4.49102
177 3VPH OXM 4.51613
178 3VPH NAD 4.51613
179 2I3G NAP 4.54545
180 3WBF NAP 4.59016
181 4XQC NAD 4.7619
182 1K3T BRZ 4.7619
183 4XQC 13D 4.7619
184 1PL6 NAD 4.77528
185 1PL6 572 4.77528
186 6CEP NAD 4.79042
187 6CEP OXM 4.79042
188 1HDG NAD 4.81928
189 1CER NAD 4.83384
190 2GCG NDP 4.84848
191 1UXG FUM 4.85437
192 1UXG NAD 4.85437
193 2HJR APR 4.87805
194 2CVQ NDP 4.89297
195 5OJL TXP 5.03356
196 2PV7 NAD 5.03356
197 4Y1B NAP 5.04202
198 1YQD NAP 5.04202
199 6C4N NAP 5.04202
200 1X87 NAD 5.04202
201 1SAY PYR 5.04202
202 1GAD NAD 5.15152
203 1GUZ NAD 5.16129
204 3B1F NAD 5.17241
205 5CAD PCA 5.32213
206 1SC6 NAD 5.32213
207 4XYB NDP 5.32213
208 3V1Y NAD 5.34125
209 2VT3 ATP 5.5814
210 5Z21 NAI 5.60224
211 4L8V NAP 5.63798
212 5EES NAP 5.66802
213 5TC4 NAD 5.6962
214 1UI0 URA 5.85366
215 4LUT DCS 5.88235
216 1BW9 NAD 5.89888
217 1BW9 PPY 5.89888
218 1C1X NAD 5.91549
219 1C1D PHE 5.91549
220 3H9E NAD 6.06936
221 2EV9 NAP 6.08365
222 2EV9 SKM 6.08365
223 2BGM NAJ 6.11511
224 1GV0 NAD 6.12903
225 1NVM NAD 6.16247
226 1DIG NAP 6.20915
227 4I9B 1KA 6.44258
228 5N2I NAP 6.46552
229 3L4S NAD 6.54762
230 5MTE BB2 6.56934
231 5L4L NAP 6.57895
232 1R4W GSH 6.63717
233 3B6Z CO7 6.72269
234 3WLE NAD 6.74487
235 1SQL GUN 6.84932
236 3NGL NAP 6.88406
237 1LOJ URI 6.89655
238 2FZW NAD 7.0028
239 4G2R H1L 7.0028
240 1YS4 NAP 7.06215
241 2OOR NAD 7.28291
242 1FDJ 13P 7.28291
243 3A06 NDP 7.28291
244 1U3U NAD 7.48663
245 1U3U BNF 7.48663
246 4POS NAG SIA GAL 7.55396
247 1RM0 D6P 7.56302
248 2ALG DAO 7.6087
249 2ALG HP6 7.6087
250 2II3 CAO 7.63359
251 1YKF NAP 7.67045
252 4RQU NAD 7.73333
253 3BAZ NAP 7.84314
254 1GPJ CIT 7.84314
255 1HYE NAP 7.98722
256 1VKO NAD 8.12325
257 1XVB BHL 8.23529
258 2CDC XYS 8.40336
259 2CDC NAP 8.40336
260 2CDC XYP 8.40336
261 4CQM NAP 8.42912
262 1EZ4 NAD 8.49057
263 3GGO NAI 8.59873
264 1F8F NAD 8.68347
265 5EY0 GTP 8.68347
266 4W6Z 8ID 8.93372
267 1EBF NAD 8.93855
268 1J0X NAD 8.96359
269 4GKV NAD 9.52381
270 1OMO NAD 9.62733
271 4OM8 NAD 9.70874
272 3QV1 NAD 9.7561
273 3CH6 311 9.79021
274 3CH6 NAP 9.79021
275 6FTB M0E 10
276 4JBI NDP 10.084
277 1LUA NAP 10.1045
278 3U6W KIV 10.3045
279 1H70 CIR 10.5882
280 4JCA CIT 10.7784
281 1PZG A3D 10.8761
282 2P3V SRT 10.9375
283 2DC1 NAD 11.0169
284 6EOM ALA LYS 11.2045
285 2JHF NAD 11.7647
286 1P0F NAP 12.0643
287 5O9F NAD 13.3523
288 5O9F 9ON 13.3523
289 1DMH MCT 13.8264
290 1F06 2NP 14.375
291 1F06 NDP 14.375
292 6AA8 NAD 14.5695
293 4IDC 1XX 15.9639
294 4IDC NDP 15.9639
295 4RVU NDP 16.5663
296 3QWB NDP 16.7665
297 1KEV NDP 17.3789
298 1NVT NAP 21.9512
299 4RJD TFP 22.7273
300 2J8Z NAP 22.9692
301 1H2B NAJ 23.2493
302 1R37 NAD 23.9193
303 2DT5 NAD 24.1706
304 1YB5 NAP 25.641
305 5DP2 NAP 25.731
306 4WAS COO 26.0504
307 4WAS NAP 26.0504
308 1N9G NAP 26.6106
309 5DOZ NDP 27.5148
310 3JYN NDP 28
Pocket No.: 2; Query (leader) PDB : 2ZB4; Ligand: NAP; Similar sites found with APoc: 306
This union binding pocket(no: 2) in the query (biounit: 2zb4.bio1) has 38 residues
No: Leader PDB Ligand Sequence Similarity
1 2WCV FUC None
2 3I6B KDO None
3 4CP8 MLI 1.40056
4 3DLS ADP 1.49254
5 6MDE MEV 1.65016
6 5YEC ATP 1.68067
7 1GQ2 NAP 1.68067
8 5TSU CYS 1.68067
9 1GR0 NAD 1.68067
10 6APL C5P 1.68067
11 1LLU NAD 1.75439
12 4MP8 MLI 1.76991
13 4MP8 NAD 1.76991
14 4BVA NDP 1.79104
15 4BVA T3 1.79104
16 4E5N NAD 1.81818
17 2PK3 A2R 1.86916
18 5X20 NAD 1.92308
19 4D3F NAP 1.93548
20 1D1T NAD 1.96078
21 1CDO NAD 1.96078
22 2VHW NAI 1.96078
23 4OOE NDP 1.96078
24 2HIM ASP 1.96078
25 1VI2 NAD 2
26 5UR0 NAD 2.00573
27 2HW1 FRU 2.01342
28 2B4R AES 2.02899
29 2B4R NAD 2.02899
30 5GLN XYP XYP XYP 2.03488
31 1WP4 NDP 2.07612
32 1NPD NAD 2.08333
33 4XB2 NDP 2.08955
34 4XB2 HSE 2.08955
35 5U5N NAD 2.15054
36 2A92 NAI 2.18069
37 4A0S NAP 2.2409
38 2CDU ADP 2.2409
39 1E3I CXF 2.2409
40 1LTH NAD 2.2409
41 4UP4 NDG 2.2409
42 1O0S NAI 2.2409
43 2B5W NAP 2.2409
44 6F3N ADN 2.2409
45 3ABI NAD 2.2409
46 6F3N NAD 2.2409
47 6F3M NAD 2.2409
48 1BXG NAD 2.24719
49 3OND NAD 2.2541
50 3OND ADN 2.2541
51 1I36 NAP 2.27273
52 5Z20 NAI 2.31884
53 5YU3 NAD 2.32558
54 5YU3 PRO 2.32558
55 1Z82 NDP 2.38806
56 5OCM NAP 2.4055
57 2F1K NAP 2.50896
58 6BII NAP 2.52101
59 4IYO NAK 2.52101
60 1KOL NAD 2.52101
61 2JLR ANP 2.52101
62 1KYQ NAD 2.55474
63 5KKA 6V0 2.5641
64 2Q0L NAP 2.57235
65 5A04 NDP 2.65487
66 5A04 BGC 2.65487
67 5TZO 7V7 2.65957
68 4JK3 NAD 2.7027
69 4J4H NAI 2.7027
70 4J4H 1J1 2.7027
71 9LDT NAD 2.71084
72 9LDB NAD 2.71084
73 1B8U NAD 2.73556
74 3L9W AMP 2.80112
75 5M67 NAD 2.80112
76 5M67 ADE 2.80112
77 5M67 3D1 2.80112
78 3X01 AMP 2.80112
79 1GZ4 ATP 2.80112
80 6A3J NAI 2.80112
81 5ZZ6 NAD 2.88462
82 1DCP HBI 2.88462
83 1DRV A3D 2.9304
84 5A1T NAI 2.93255
85 5A1T OXM 2.93255
86 3B1J NAD 2.94985
87 3B20 NAD 2.94985
88 5D4V SAH 2.98507
89 3KB6 NAD 2.99401
90 5N6C NAD 3
91 1J49 NAD 3.003
92 5NUF NAD 3.01205
93 5NUE NAD 3.01205
94 4ZVV GN0 3.01205
95 4ZVV NAD 3.01205
96 1W2D ADP 3.01887
97 1LDM NAD 3.03951
98 2AG8 NAP 3.04183
99 1VM6 NAD 3.07018
100 4ARE FLC 3.08123
101 3CIF NAD 3.08123
102 4ZGS NAD 3.08123
103 1HKU NAD 3.08123
104 3CIF G3H 3.08123
105 1J5P NAD 3.16206
106 1LDN NAD 3.16456
107 1Q8S MAN MMA 3.1746
108 2PHX MAN MAN 3.1746
109 1Q8Q MAN MMA 3.1746
110 6BJO DUY 3.2
111 4Y9D NAI 3.27869
112 5JE8 NAD 3.31126
113 1NYT NAP 3.32103
114 4PLT NAI 3.32326
115 4PLT OXM 3.32326
116 5H81 NAP 3.36134
117 1O6Z NAD 3.36134
118 1F8G NAD 3.36134
119 5FI3 NAP 3.36134
120 1PJS NAD 3.36134
121 4BE9 7P9 3.36134
122 2GZ3 NAP 3.36134
123 1T26 NAI 3.41615
124 1T26 GBD 3.41615
125 3I7S PYR 3.42466
126 1ZEM NAD 3.43511
127 3TWO NDP 3.44828
128 5ZI2 NAD 3.47826
129 1DQN IMU 3.47826
130 5ZI2 ADP 3.47826
131 4Z3E GAL NGA GLA BGC GAL 3.53535
132 2Q46 NAP 3.55731
133 1HYH NAD 3.55987
134 5CGE 51F 3.61011
135 1E5Q NDP 3.64146
136 3NJ4 NAD 3.64146
137 3NJ4 AFX 3.64146
138 2D2I NAP 3.64146
139 6C4T NA7 3.64146
140 5GZ6 NDP 3.68098
141 5GZ6 7C3 3.68098
142 3GFB NAD 3.71429
143 2JL1 NAP 3.83275
144 4MDH NAD 3.89222
145 5MDH NAD 3.9039
146 4AVB CMP 3.9039
147 2DFV NAD 3.92157
148 5VKT NAP 3.92157
149 2VYN NAD 3.92157
150 1CY2 TMP 3.92157
151 5LD5 NAD 3.92157
152 5DN9 NAD 3.92157
153 2HK9 ATR 4
154 1X7D NAD 4
155 2HK9 NAP 4
156 1X7D ORN 4
157 1P77 ATR 4.04412
158 4PLG OXM 4.19162
159 4PLG NAI 4.19162
160 1V8B NAD 4.20168
161 4DPL NAP 4.20168
162 5AOV NAP 4.20168
163 1SOW NAD 4.26829
164 1LSS NAD 4.28571
165 2JK0 ASP 4.30769
166 4XZ3 COA 4.34783
167 5NGL NOJ BGC 4.48179
168 2ZJ1 ARJ 4.48179
169 2ZJ1 NAD 4.48179
170 4Z0H NAD 4.48179
171 1OFZ FUC 4.48718
172 1OFZ FUL 4.48718
173 2DBZ NAP 4.49102
174 3VPH OXM 4.51613
175 3VPH NAD 4.51613
176 2I3G NAP 4.54545
177 3WBF NAP 4.59016
178 5N53 8NB 4.61538
179 4XQC NAD 4.7619
180 1PL6 572 4.77528
181 1PL6 NAD 4.77528
182 6CEP NAD 4.79042
183 6CEP OXM 4.79042
184 1HDG NAD 4.81928
185 1CER NAD 4.83384
186 2GCG NDP 4.84848
187 1UXG NAD 4.85437
188 1UXG FUM 4.85437
189 2HJR APR 4.87805
190 2CVQ NDP 4.89297
191 5OJL TXP 5.03356
192 2PV7 NAD 5.03356
193 4Y1B NAP 5.04202
194 1YQD NAP 5.04202
195 6C4N NAP 5.04202
196 1X87 NAD 5.04202
197 1SAY PYR 5.04202
198 1GAD NAD 5.15152
199 1GUZ NAD 5.16129
200 3B1F NAD 5.17241
201 5CAD PCA 5.32213
202 1SC6 NAD 5.32213
203 4XYB NDP 5.32213
204 3V1Y NAD 5.34125
205 2VT3 ATP 5.5814
206 5Z21 NAI 5.60224
207 5EES NAP 5.66802
208 5TC4 NAD 5.6962
209 1UI0 URA 5.85366
210 4LUT DCS 5.88235
211 1BW9 NAD 5.89888
212 1BW9 PPY 5.89888
213 1C1X NAD 5.91549
214 1C1D PHE 5.91549
215 3H9E NAD 6.06936
216 2EV9 NAP 6.08365
217 2EV9 SKM 6.08365
218 2BGM NAJ 6.11511
219 1GV0 NAD 6.12903
220 1NVM NAD 6.16247
221 1DIG NAP 6.20915
222 4I9B 1KA 6.44258
223 5N2I NAP 6.46552
224 3L4S NAD 6.54762
225 5MTE BB2 6.56934
226 5L4L NAP 6.57895
227 4WNP 3RJ 6.62021
228 1R4W GSH 6.63717
229 3B6Z CO7 6.72269
230 3WLE NAD 6.74487
231 1SQL GUN 6.84932
232 3NGL NAP 6.88406
233 1LOJ URI 6.89655
234 2FZW NAD 7.0028
235 4G2R H1L 7.0028
236 1YS4 NAP 7.06215
237 2OOR NAD 7.28291
238 1FDJ 13P 7.28291
239 3A06 NDP 7.28291
240 1U3U BNF 7.48663
241 1U3U NAD 7.48663
242 1DSS NAD 7.50751
243 4POS NAG SIA GAL 7.55396
244 1RM0 D6P 7.56302
245 2ALG DAO 7.6087
246 2ALG HP6 7.6087
247 1YKF NAP 7.67045
248 4RQU NAD 7.73333
249 3BAZ NAP 7.84314
250 1GPJ CIT 7.84314
251 1HYE NAP 7.98722
252 1VKO NAD 8.12325
253 2CDC NAP 8.40336
254 2CDC XYP 8.40336
255 2CDC XYS 8.40336
256 4CQM NAP 8.42912
257 1EZ4 NAD 8.49057
258 3GGO NAI 8.59873
259 1F8F NAD 8.68347
260 5XQW 8EU 8.75576
261 4W6Z 8ID 8.93372
262 1EBF NAD 8.93855
263 1J0X NAD 8.96359
264 2HJ9 AI2 9.04977
265 4GKV NAD 9.52381
266 1OMO NAD 9.62733
267 4OM8 NAD 9.70874
268 3QV1 NAD 9.7561
269 3CH6 NAP 9.79021
270 3CH6 311 9.79021
271 6FTB M0E 10
272 4JBI NDP 10.084
273 1LUA NAP 10.1045
274 3U6W KIV 10.3045
275 1H70 CIR 10.5882
276 4JCA CIT 10.7784
277 1PZG A3D 10.8761
278 2P3V SRT 10.9375
279 2DC1 NAD 11.0169
280 6EOM ALA LYS 11.2045
281 2JHF NAD 11.7647
282 1P0F NAP 12.0643
283 5O9F 9ON 13.3523
284 5O9F NAD 13.3523
285 1DMH MCT 13.8264
286 1F06 2NP 14.375
287 1F06 NDP 14.375
288 6AA8 NAD 14.5695
289 4IDC NDP 15.9639
290 4IDC 1XX 15.9639
291 4RVU NDP 16.5663
292 3QWB NDP 16.7665
293 1KEV NDP 17.3789
294 1NVT NAP 21.9512
295 4RJD TFP 22.7273
296 2J8Z NAP 22.9692
297 1H2B NAJ 23.2493
298 1R37 NAD 23.9193
299 2DT5 NAD 24.1706
300 1YB5 NAP 25.641
301 5DP2 NAP 25.731
302 4WAS COO 26.0504
303 4WAS NAP 26.0504
304 1N9G NAP 26.6106
305 5DOZ NDP 27.5148
306 3JYN NDP 28
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