Receptor
PDB id Resolution Class Description Source Keywords
2Z6D 2 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF LOV1 DOMAIN OF PHOTOTROPIN2 FROM ARABIDOPSIS THALIANA ARABIDOPSIS THALIANA PAS-FOLD LOV-FOLD ALTERNATIVE SPLICING ATP-BINDING CHROMOPHORE FLAVOPROTEIN FMN KINASE MEMBRANE NUCLEOTIDE-BINDING PHOSPHORYLATION PHOTORECEPTOR PROTEINRECEPTOR SENSORY TRANSDUCTION SERINE/THREONINE-PROTEIN KINASE TRANSFERASE
Ref.: STRUCTURAL BASIS OF THE LOV1 DIMERIZATION OF ARABIDOPSIS PHOTOTROPINS 1 AND 2 J.MOL.BIOL. V. 381 718 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FMN A:500;
B:500;
Valid;
Valid;
none;
none;
submit data
456.344 C17 H21 N4 O9 P Cc1cc...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2Z6D 2 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF LOV1 DOMAIN OF PHOTOTROPIN2 FROM ARABIDOPSIS THALIANA ARABIDOPSIS THALIANA PAS-FOLD LOV-FOLD ALTERNATIVE SPLICING ATP-BINDING CHROMOPHORE FLAVOPROTEIN FMN KINASE MEMBRANE NUCLEOTIDE-BINDING PHOSPHORYLATION PHOTORECEPTOR PROTEINRECEPTOR SENSORY TRANSDUCTION SERINE/THREONINE-PROTEIN KINASE TRANSFERASE
Ref.: STRUCTURAL BASIS OF THE LOV1 DIMERIZATION OF ARABIDOPSIS PHOTOTROPINS 1 AND 2 J.MOL.BIOL. V. 381 718 2008
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 107 families.
1 2Z6D - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 82 families.
1 2Z6C - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
2 2Z6D - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
50% Homology Family (17)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 141 families.
1 2PR5 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
2 1N9L - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
3 1N9N - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
4 3T50 - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
5 2Z6C - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
6 4EES - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
7 4EET - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
8 4NXE - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
9 4EER - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
10 4NXG - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
11 4NXF - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
12 4EEP - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
13 4EEU - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
14 2V1A - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
15 2V0U - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
16 5DKK - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
17 2Z6D - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FMN; Similar ligands found: 16
No: Ligand ECFP6 Tc MDL keys Tc
1 FMN 1 1
2 RBF 0.75641 0.876712
3 RS3 0.571429 0.831169
4 FAS 0.543307 0.876543
5 FAD 0.543307 0.876543
6 FAE 0.539062 0.865854
7 DAL FAD PER 0.5 0.833333
8 LFN 0.475 0.643836
9 C3F 0.473684 0.74359
10 CF4 0.463918 0.734177
11 FAY 0.446043 0.864198
12 FNR 0.444444 0.909091
13 RFL 0.442857 0.845238
14 4LS 0.411215 0.875
15 1VY 0.406593 0.769231
16 DLZ 0.404494 0.782051
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2Z6D; Ligand: FMN; Similar sites found: 158
This union binding pocket(no: 1) in the query (biounit: 2z6d.bio1) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5U9J GER 0.0009004 0.46801 None
2 2IYG FMN 0.0008117 0.45912 None
3 1YRX FMN 0.0006569 0.45337 None
4 1ECM TSA 0.003665 0.43785 None
5 4WG0 CHD 0.007886 0.42589 None
6 2X32 OTP 0.0115 0.42132 None
7 4CS4 AXZ 0.01224 0.41831 None
8 1L0I PSR 0.01254 0.41492 None
9 5AIG VPR 0.01002 0.41183 None
10 5MWE TCE 0.01629 0.41007 None
11 4CS4 ANP 0.01603 0.40718 None
12 3T2W BTN 0.01301 0.40633 None
13 5ML3 DL3 0.01868 0.40307 None
14 2Z77 HE7 0.004144 0.40212 None
15 4NS0 PIO 0.02342 0.40147 None
16 2LBD REA 0.01077 0.40041 None
17 4GJ3 0XP 0.01047 0.40783 1.53846
18 1XZ3 ICF 0.0124 0.437 2.30769
19 4MGA 27L 0.007681 0.43165 2.30769
20 1EPB REA 0.002106 0.43067 2.30769
21 4MG8 27J 0.006482 0.41258 2.30769
22 4Z28 BTN 0.01263 0.40697 2.30769
23 4TUZ 36J 0.01051 0.40675 2.30769
24 3WCS MAN NAG GAL 0.01477 0.40366 2.30769
25 4XAC AKG 0.0236 0.40307 2.30769
26 4RQL SNE 0.01894 0.40243 2.30769
27 4TW7 37K 0.01174 0.40022 2.34375
28 2HZQ STR 0.005212 0.43829 3.07692
29 3T4L ZEA 0.001158 0.43792 3.07692
30 2AGC DAO 0.004307 0.43438 3.07692
31 1DZK PRZ 0.003343 0.42165 3.07692
32 4BG4 ADP 0.003334 0.41401 3.07692
33 3QCP FAD 0.01042 0.40254 3.07692
34 3KU0 ADE 0.02749 0.40137 3.07692
35 5D9G GLU ASN LEU TYR PHE GLN 0.02009 0.40115 3.07692
36 5FUI APY 0.005009 0.442 3.84615
37 3L24 GOA 0.00604 0.42769 3.84615
38 1MDC PLM 0.002272 0.4269 3.84615
39 1KC7 PPR 0.01096 0.41562 3.84615
40 4Y2B EPK 0.01293 0.4152 3.84615
41 4A38 BZS 0.01302 0.41519 3.84615
42 4NG2 OHN 0.006067 0.41147 3.84615
43 2QZZ EMF 0.01404 0.41086 3.84615
44 2OHV NHL 0.01508 0.40737 3.84615
45 2QZZ NAP 0.01591 0.40733 3.84615
46 1ERB ETR 0.009425 0.40591 3.84615
47 5EOB 5QQ 0.03063 0.40469 3.84615
48 4FGC PQ0 0.02231 0.40444 3.84615
49 5JSP DQY 0.001667 0.46339 4.61538
50 4XBT 3ZQ 0.001931 0.44142 4.61538
51 4MRP GSH 0.008002 0.43349 4.61538
52 4JH6 FCN 0.00619 0.42657 4.61538
53 3VQ2 LP4 LP5 MYR DAO 0.008563 0.42382 4.61538
54 1SN0 T44 0.006372 0.41701 4.61538
55 3SHZ 5CO 0.008216 0.416 4.61538
56 1SR7 MOF 0.008798 0.41252 4.61538
57 3E9I XAH 0.008339 0.41102 4.61538
58 5XDT ZI7 0.009007 0.40679 4.61538
59 3NZ1 3NY 0.01977 0.40677 4.61538
60 2G30 ALA ALA PHE 0.00009825 0.51373 5.38462
61 1GQG DCD 0.001142 0.43996 5.38462
62 1ZOY UQ1 0.006577 0.43421 5.38462
63 3WV6 GAL GLC 0.00858 0.42266 5.38462
64 4UY1 TJM 0.006031 0.41813 5.38462
65 3WV6 GAL BGC 0.01347 0.41763 5.38462
66 4DQ2 BTX 0.006541 0.41578 5.38462
67 5MRH Q9Z 0.01198 0.41234 5.38462
68 4EKV BTN 0.008343 0.41148 5.38462
69 2XN5 FUN 0.01037 0.41111 5.38462
70 4Y85 499 0.006868 0.40759 5.38462
71 4WVW SLT 0.009319 0.40586 5.38462
72 3T1A 5MA 0.005927 0.40326 5.38462
73 4KBA 1QM 0.01897 0.40239 5.38462
74 4BJ8 BTN 0.006283 0.40934 5.55556
75 1JIF CU BLM 0.009593 0.40556 5.7377
76 3RGA LSB 0.00054 0.45719 6.15385
77 1M2Z BOG 0.02716 0.42079 6.15385
78 5KJW 53C 0.0165 0.41429 6.15385
79 2CHG ANP 0.002458 0.40771 6.15385
80 4YRD 3IT 0.01137 0.40739 6.15385
81 3BRN SRO 0.0249 0.40172 6.15385
82 5N6Y HCA 0.01985 0.40095 6.15385
83 1NHZ 486 0.009222 0.40026 6.15385
84 3W54 RNB 0.001605 0.44045 6.92308
85 3KMZ EQO 0.002362 0.4312 6.92308
86 2GC0 PAN 0.002035 0.42718 6.92308
87 2BCG GER 0.006355 0.42601 6.92308
88 1M15 ADP 0.008359 0.41594 6.92308
89 1M15 ARG 0.008359 0.41594 6.92308
90 3A6T 8OG 0.005992 0.41026 6.97674
91 1LRI CLR 0.001473 0.43693 7.14286
92 1Y75 NAG 0.009893 0.41647 7.62712
93 5A5W GUO 0.004379 0.43551 7.69231
94 4XCB AKG 0.009836 0.42127 7.69231
95 1X0P FAD 0.001436 0.4182 7.69231
96 1I06 TZL 0.01511 0.41175 7.69231
97 4FFG LBS 0.01866 0.4085 7.69231
98 1QY1 PRZ 0.003393 0.40164 7.69231
99 4D4U FUC NDG GAL FUC 0.006477 0.43691 8.46154
100 3X01 AMP 0.0153 0.41286 8.46154
101 1X8X TYR 0.01129 0.40931 8.46154
102 2C9O ADP 0.003467 0.408 8.46154
103 3ANY 2A3 0.02429 0.40543 8.46154
104 1LNX URI 0.02518 0.40126 8.64198
105 3PUR 2HG 0.001347 0.46837 9.23077
106 3N9O OGA 0.001606 0.46593 9.23077
107 4QCK ASD 0.002081 0.43527 9.23077
108 4N14 WR7 0.003815 0.42465 9.23077
109 4YVN EBS 0.009804 0.42384 9.23077
110 5IR4 ZPE 0.01262 0.41588 9.23077
111 3UNG ADP 0.01605 0.41053 9.23077
112 2A1L PCW 0.01759 0.40995 9.23077
113 3KP6 SAL 0.00954 0.43915 10
114 2HFN FMN 0.001885 0.42864 10
115 3FAL REA 0.007322 0.41842 10
116 4YZC STU 0.01428 0.40745 10
117 3W68 VIV 0.007884 0.40324 10
118 1KJ1 MAN 0.02562 0.40116 10.0917
119 5L2J 6UL 0.01003 0.43521 10.7692
120 5L2J 70E 0.01064 0.43521 10.7692
121 2Q8H TF4 0.01783 0.41406 10.7692
122 5IKI A9H 0.01167 0.41291 10.7692
123 1W6P NDG GAL 0.007284 0.41124 10.7692
124 3GFZ FMN 0.00233 0.40405 10.7692
125 2AIB ERG 0.002056 0.43388 11.2245
126 4LED XXR 0.008066 0.41648 11.5385
127 1KOL NAD 0.01594 0.40627 11.5385
128 5CJ3 52G 0.01174 0.40558 11.5385
129 2IV2 MGD 0.01861 0.40314 11.5385
130 1JLX GAL A2G MBN 0.02572 0.40094 11.5385
131 4IAW LIZ 0.009051 0.41397 12.3077
132 2R0D 4IP 0.01021 0.42044 13.0769
133 3DOO SKM 0.01599 0.41144 13.0769
134 4UCC ZKW 0.02442 0.40264 13.0769
135 2BYC FMN 0.0007047 0.45687 14.6154
136 1PS9 FAD 0.01053 0.4196 15.3846
137 4BVA T3 0.00153 0.45572 16.1538
138 2YJD YJD 0.008341 0.4038 16.1538
139 2OVW CBI 0.02187 0.40353 16.1538
140 4REI 3MV 0.01545 0.41186 16.9231
141 5KEW 6SB 0.02557 0.40148 18.0851
142 4GGZ BTN 0.01164 0.40464 18.2609
143 4L6H HCS 0.0207 0.40569 18.4615
144 3H0L ADP 0.007943 0.4212 19.2308
145 1UGY GLA GLC 0.005393 0.41804 19.2308
146 4XT2 43L 0.001367 0.4153 20.5128
147 1QKQ MAN 0.001951 0.43261 22.3077
148 3G5D 1N1 0.01117 0.4267 22.3077
149 1UO5 PIH 0.006196 0.45491 23.5294
150 2J3M PRI 0.007205 0.40659 29.2308
151 4L4J NAG NAG BMA MAN NAG 0.009165 0.41797 30.7692
152 5MBC FMN 0.0006799 0.4527 33.8462
153 4HIA FMN 0.00000000005482 0.79241 42.3077
154 3EWK FAD 0.00006289 0.48804 44.6154
155 3IS2 FAD 0.0000000000001849 0.88678 45.3846
156 3P7N FMN 0.0000000000003532 0.84211 45.3846
157 3D72 FAD 0.0000000000001126 0.67955 45.3846
158 2GJ3 FAD 0.0000003183 0.58656 47.5
Pocket No.: 2; Query (leader) PDB : 2Z6D; Ligand: FMN; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2z6d.bio1) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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