Receptor
PDB id Resolution Class Description Source Keywords
2Z5Y 2.17 Å EC: 1.4.3.4 CRYSTAL STRUCTURE OF HUMAN MONOAMINE OXIDASE A (G110A) WITH HARMINE HOMO SAPIENS HUMAN MONOAMINE OXIDASE A MUTANT G110A FAD HARMINE DIMETHYLDECYLPHOSPHINE OXIDE SINGLE HELIX TRANS-MEMBRANE PROTEIN ACETYLATION CATECHOLAMINE METABOLISM FLAVOPROTEIN MITOCHONDRION NEUROTRANSMITTER DEGRADATION OXIDOREDUCTASE POLYMORPHISM TRANSMEMBRANE
Ref.: STRUCTURE OF HUMAN MONOAMINE OXIDASE A AT 2.2-A RESOLUTION: THE CONTROL OF OPENING THE ENTRY FOR SUBSTRATES/INHIBITORS PROC.NATL.ACAD.SCI.USA V. 105 5739 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DCX A:1;
A:2;
 Invalid;
Invalid;
 none;
none;
 submit data
218.316 C12 H27 O P CCCCC...
FAD A:600;
 Invalid;
 none;
 submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
HRM A:700;
 Valid;
 none;
 submit data
212.247 C13 H12 N2 O Cc1c2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2Z5Y 2.17 Å EC: 1.4.3.4 CRYSTAL STRUCTURE OF HUMAN MONOAMINE OXIDASE A (G110A) WITH HARMINE HOMO SAPIENS HUMAN MONOAMINE OXIDASE A MUTANT G110A FAD HARMINE DIMETHYLDECYLPHOSPHINE OXIDE SINGLE HELIX TRANS-MEMBRANE PROTEIN ACETYLATION CATECHOLAMINE METABOLISM FLAVOPROTEIN MITOCHONDRION NEUROTRANSMITTER DEGRADATION OXIDOREDUCTASE POLYMORPHISM TRANSMEMBRANE
Ref.: STRUCTURE OF HUMAN MONOAMINE OXIDASE A AT 2.2-A RESOLUTION: THE CONTROL OF OPENING THE ENTRY FOR SUBSTRATES/INHIBITORS PROC.NATL.ACAD.SCI.USA V. 105 5739 2008
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 2Z5Y - HRM C13 H12 N2 O Cc1c2c(ccn....
2 2Z5X - HRM C13 H12 N2 O Cc1c2c(ccn....
70% Homology Family (20)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2Z5Y - HRM C13 H12 N2 O Cc1c2c(ccn....
2 2Z5X - HRM C13 H12 N2 O Cc1c2c(ccn....
3 2BK3 Ki = 2.3 uM FOH C15 H26 O CC(=CCC/C(....
4 1OJA Ki = 3 uM ISN C8 H5 N O2 c1ccc2c(c1....
5 2XFO Ki = 58 uM XCG C11 H8 N2 O c1ccc2c(c1....
6 1OJ9 Ki = 35 uM 1PB C16 H16 c1ccc(cc1)....
7 2XCG Kd = 9 nM XCG C11 H8 N2 O c1ccc2c(c1....
8 3PO7 Ki = 3.1 uM ZON C8 H8 N2 O3 S c1ccc2c(c1....
9 2BK5 Ki = 3 uM ISN C8 H5 N O2 c1ccc2c(c1....
10 2V5Z Ki = 0.45 uM SAG C17 H17 F N2 O2 C[C@@H](C(....
11 2XFN Ki = 8.3 uM XCG C11 H8 N2 O c1ccc2c(c1....
12 3ZYX Ki = 0.143 uM MBT C16 H18 N3 S CN(C)c1ccc....
13 2C67 Ki = 17 uM RM1 C10 H13 N CN[C@@H]1C....
14 2C70 - PNZ C7 H8 N2 O2 c1cc(ccc1C....
15 4A79 Ki = 0.5 uM P1B C19 H20 N2 O3 S CCc1ccc(nc....
16 4A7A Ki = 4.2 uM RGZ C18 H19 N3 O3 S CN(CCOc1cc....
17 2V61 Ki = 0.1 uM C18 C18 H16 Cl N O3 CNCC1=CC(=....
18 2XFP - ISN C8 H5 N O2 c1ccc2c(c1....
19 2V60 Ki = 0.4 uM C17 C17 H11 Cl O4 c1cc(cc(c1....
20 2XFQ - XCG C11 H8 N2 O c1ccc2c(c1....
50% Homology Family (20)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2Z5Y - HRM C13 H12 N2 O Cc1c2c(ccn....
2 2Z5X - HRM C13 H12 N2 O Cc1c2c(ccn....
3 2BK3 Ki = 2.3 uM FOH C15 H26 O CC(=CCC/C(....
4 1OJA Ki = 3 uM ISN C8 H5 N O2 c1ccc2c(c1....
5 2XFO Ki = 58 uM XCG C11 H8 N2 O c1ccc2c(c1....
6 1OJ9 Ki = 35 uM 1PB C16 H16 c1ccc(cc1)....
7 2XCG Kd = 9 nM XCG C11 H8 N2 O c1ccc2c(c1....
8 3PO7 Ki = 3.1 uM ZON C8 H8 N2 O3 S c1ccc2c(c1....
9 2BK5 Ki = 3 uM ISN C8 H5 N O2 c1ccc2c(c1....
10 2V5Z Ki = 0.45 uM SAG C17 H17 F N2 O2 C[C@@H](C(....
11 2XFN Ki = 8.3 uM XCG C11 H8 N2 O c1ccc2c(c1....
12 3ZYX Ki = 0.143 uM MBT C16 H18 N3 S CN(C)c1ccc....
13 2C67 Ki = 17 uM RM1 C10 H13 N CN[C@@H]1C....
14 2C70 - PNZ C7 H8 N2 O2 c1cc(ccc1C....
15 4A79 Ki = 0.5 uM P1B C19 H20 N2 O3 S CCc1ccc(nc....
16 4A7A Ki = 4.2 uM RGZ C18 H19 N3 O3 S CN(CCOc1cc....
17 2V61 Ki = 0.1 uM C18 C18 H16 Cl N O3 CNCC1=CC(=....
18 2XFP - ISN C8 H5 N O2 c1ccc2c(c1....
19 2V60 Ki = 0.4 uM C17 C17 H11 Cl O4 c1cc(cc(c1....
20 2XFQ - XCG C11 H8 N2 O c1ccc2c(c1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: HRM; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 HRM 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2Z5Y; Ligand: HRM; Similar sites found: 289
This union binding pocket(no: 1) in the query (biounit: 2z5y.bio2) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3KPE TM3 0.0003243 0.49475 None
2 1TUV VK3 0.002237 0.47892 None
3 4TSK NDP 0.0009141 0.42165 1.42857
4 3TO7 COA 0.0005012 0.41318 1.44928
5 1HV9 UD1 0.0007845 0.41383 1.53509
6 1HV9 COA 0.001063 0.4112 1.53509
7 1ZFJ IMP 0.0002491 0.46176 1.62933
8 1V8K ANP 0.0001214 0.42182 1.70732
9 3O9P MHI 0.00004635 0.46962 1.75439
10 2BJK NAD 0.002821 0.40312 1.75439
11 4GZP G39 0.0007119 0.40974 1.78117
12 1LDM NAD 0.00001628 0.48369 1.82371
13 4A3R CIT 0.00003528 0.44367 1.86047
14 4CMF PXG 0.000004123 0.49065 1.86335
15 1GSA ADP 0.000003943 0.48886 1.89873
16 1GSA GSH 0.0004952 0.4168 1.89873
17 1QJC PNS 0.002106 0.40717 1.89873
18 4LCQ URQ 0.0001502 0.41592 1.94932
19 2Z81 PCJ 0.01948 0.41393 1.94932
20 2Z9V PXM 0.02077 0.40129 2.04082
21 4QN7 G39 0.000192 0.42182 2.05128
22 2RDT 2RD 0.000004376 0.50428 2.06718
23 2RDT FMN 0.0003901 0.43186 2.06718
24 4Q3S X7A 0.0007192 0.40589 2.07792
25 1FWY UD1 0.0003455 0.41009 2.1148
26 2VJJ RAM GLC GAL NAG NAG GLC 0.001527 0.40905 2.14425
27 1K0E TRP 0.00746 0.4164 2.20751
28 2W8Q SIN 0.0000006736 0.45229 2.25873
29 3MAG 3MA 0.01471 0.44387 2.28013
30 2R0N TGC 0.00005957 0.49407 2.28426
31 2R0N FAD 0.001823 0.42526 2.28426
32 3VHZ L2P GLC MAN SGA 0.002346 0.4145 2.29008
33 2IMP NAI 0.00001136 0.49876 2.29645
34 2IMP LAC 0.000001811 0.43416 2.29645
35 1X1T NAD 0.0003908 0.44274 2.30769
36 1RYD GLC 0.003658 0.43588 2.32558
37 4C0C WVH 0.00005407 0.44983 2.35546
38 4IXW IXW 0.01729 0.40043 2.3622
39 3L8W XAN 0.000002807 0.50268 2.36486
40 4DA6 GA2 0.001277 0.41536 2.37154
41 1RM4 NDP 0.001232 0.41903 2.37389
42 3C2O NTM 0.001533 0.43221 2.38095
43 2ZX7 ZX7 0.0006346 0.40024 2.41758
44 3MMR ABH 0.0001791 0.44269 2.42131
45 1G6O ADP 0.00007198 0.45537 2.42424
46 4I9A NCN 0.0002336 0.41043 2.43056
47 2NLI LAC 0.0001252 0.44382 2.44565
48 2NLI FMN 0.0001252 0.44382 2.44565
49 2F2U M77 0.002923 0.428 2.48756
50 3SAO NKN 0.005822 0.41686 2.5
51 4QN6 LNV 0.0002355 0.42181 2.55754
52 4QDF 30Q 0.0001884 0.40881 2.5641
53 4MWV BCZ 0.0001947 0.42429 2.57732
54 2C9O ADP 0.0002191 0.41587 2.63158
55 1FS5 TLA 0.0001312 0.41288 2.63158
56 1LGT BP3 0.0002622 0.47088 2.6936
57 2YYJ FAD 0.00008768 0.47008 2.7027
58 2YYJ 4HP 0.00008768 0.47008 2.7027
59 1JQ5 NAD 0.001199 0.44871 2.7027
60 1CR1 TTP 0.001903 0.4185 2.7027
61 2BLE 5GP 0.00001352 0.48262 2.7248
62 1PJ6 FOL 0.000006547 0.47695 2.72904
63 1KOR ANP 0.03189 0.44007 2.75
64 1KOR ARG 0.03132 0.44007 2.75
65 1KOR SIN 0.03132 0.44007 2.75
66 4B7J G39 0.00005293 0.43545 2.77186
67 3CL7 HYN 0.00002146 0.42851 2.92208
68 4AF0 IMP 0.000002701 0.49401 2.92398
69 4AF0 MOA 0.00001471 0.43018 2.92398
70 3T1A 5MA 0.015 0.40748 2.92398
71 1I2B USQ 0.001774 0.44095 2.9703
72 1I2B UPG 0.001774 0.44095 2.9703
73 1I2B NAD 0.001774 0.44095 2.9703
74 3Q3C NAD 0.00003463 0.46354 3.01003
75 1ONX ASP 0.00006519 0.4339 3.07692
76 1YBQ BDH 0.0002696 0.41744 3.07692
77 4HZX G39 0.0001793 0.42789 3.09278
78 3Q2I HP7 0.002999 0.40791 3.10734
79 2QS8 MET 0.00006851 0.42569 3.11005
80 3CXO 1N5 0.000002126 0.4728 3.13253
81 3CXO 3LR 0.0002665 0.40879 3.13253
82 1LSH PLD 0.002116 0.46502 3.1348
83 1LTH NAD 0.00005151 0.45805 3.1348
84 1R0X ATP 0.0002162 0.4175 3.14685
85 1G41 ADP 0.00005206 0.45988 3.15315
86 1P4C FMN 0.0004787 0.43696 3.15789
87 2C1Q BTN 0.0001144 0.4338 3.1746
88 1ZK4 AC0 0.0002524 0.45317 3.18725
89 1ZK4 NAP 0.0002524 0.45317 3.18725
90 1W55 C 0.0007681 0.41706 3.2345
91 4COQ SAN 0.03491 0.40016 3.23887
92 1GR0 NAD 0.00004262 0.47638 3.26975
93 3K37 BCZ 0.0007645 0.43563 3.27456
94 1AL8 FMN 0.00001564 0.47235 3.34262
95 4NVP 7CH 0.000007922 0.46294 3.34928
96 1TV5 A26 0.0003125 0.4284 3.386
97 1YOE RIB 0.0001697 0.4144 3.41615
98 3ZJX BOG 0.00439 0.42877 3.46021
99 2P2V CSF 0.00001179 0.47623 3.47222
100 1YBH FAD 0.0001648 0.4633 3.50877
101 1YBH P22 0.00003958 0.43594 3.50877
102 2XD9 XD9 0.0008336 0.4568 3.59281
103 1N6B DMZ 0.00001378 0.45881 3.59408
104 1FA2 DOM 0.0001082 0.42001 3.61446
105 1VQ2 DDN 0.00002454 0.47606 3.62694
106 3NJQ NJQ 0.00008327 0.41709 3.62694
107 1DRV A3D 0.0002848 0.43057 3.663
108 1V5F FAD 0.0007769 0.46018 3.7037
109 1V5F TPP 0.0007769 0.46018 3.7037
110 3SUC ATP 0.0008517 0.40623 3.7037
111 2QLX RM4 0.04163 0.40138 3.7037
112 1X7D ORN 0.04574 0.40418 3.71429
113 1T26 NAI 0.00002041 0.49836 3.72671
114 1T26 GBD 0.00002041 0.49836 3.72671
115 3K9W 4PS 0.001346 0.43571 3.74332
116 3K9W ADE 0.001346 0.43571 3.74332
117 1KW6 BPY 0.001526 0.4175 3.76712
118 3F3E LEU 0.0006811 0.40796 3.85356
119 2R7K ACP 0.004176 0.41859 3.87812
120 2R7K AMZ 0.004176 0.41859 3.87812
121 2Q6K ADN 0.001862 0.42075 3.88693
122 3CKZ ZMR 0.0002242 0.42733 3.8961
123 3DJL FAD 0.003732 0.41355 3.89864
124 1WDA BAG 0.01668 0.4011 3.89864
125 1G8S MET 0.00589 0.4363 3.91304
126 2OWZ CIT 0.00000137 0.45114 3.91566
127 2OWZ F6P 0.0004397 0.41608 3.91566
128 1KGI T4A 0.005935 0.43454 3.93701
129 2H6B 3C4 0.0005203 0.42785 4
130 4IZC 1GZ 0.002543 0.40205 4
131 4IVG ANP 0.00007274 0.45126 4.09357
132 1O6B ADP 0.00093 0.41154 4.14201
133 4JP3 CIT 0.00002846 0.44336 4.1841
134 4TMK T5A 0.001808 0.43687 4.22535
135 1JH7 UVC 0.0006251 0.41028 4.2328
136 1MVQ MMA 0.00001771 0.44607 4.23729
137 2GGH NLQ 0.00003378 0.44423 4.26667
138 1JQN DCO 0.00003987 0.41598 4.2885
139 2P8B NSK 0.0003911 0.45905 4.33604
140 1QW9 KHP 0.00003002 0.42812 4.38247
141 1WL4 COA 0.001754 0.40202 4.53401
142 1D09 PAL 0.01546 0.40248 4.57516
143 2X61 CH 0.00001337 0.46206 4.65116
144 2X61 NGA GAL SIA 0.0002337 0.44076 4.65116
145 2ZI8 SDT 0.0005129 0.40064 4.66667
146 3VGL ANP 0.00005354 0.44112 4.6729
147 3VGL BGC 0.0001055 0.42032 4.6729
148 1JA9 NDP 0.0002095 0.45032 4.67836
149 1JA9 PYQ 0.00004728 0.43031 4.67836
150 1SAY PYR 0.000128 0.48068 4.70914
151 4P87 4NP 0.0000244 0.43321 4.73815
152 3RO7 TDR 0.0007852 0.44386 4.90566
153 1M5B BN1 0.002525 0.40741 4.94297
154 1WVC CTP 0.0006265 0.44223 5.01931
155 3D78 NBB 0.04663 0.41865 5.04202
156 3TA2 AKG 0.0004462 0.40237 5.08475
157 4OYA 1VE 0.001256 0.43827 5.10638
158 1OMZ UD2 0.001787 0.40176 5.11945
159 3FS8 ACO 0.004155 0.41083 5.12821
160 1ME8 RVP 0.00003616 0.48174 5.16899
161 3WSJ MK1 0.0004668 0.42384 5.17241
162 4QCK ASD 0.0001567 0.40681 5.18135
163 3IU9 T07 0.0003162 0.43737 5.20833
164 1SS4 GSH 0.02218 0.4441 5.22876
165 1Q3Q ANP 0.0001008 0.45254 5.26316
166 4HZD COA 0.0004635 0.41045 5.31915
167 2NSJ C2R 0.0002074 0.45192 5.32544
168 2W24 LYS 0.00004835 0.43003 5.33333
169 1XMV ADP 0.0002022 0.4382 5.33708
170 2ZO9 MLI 0.00176 0.43448 5.47445
171 3D2M COA 0.001389 0.43674 5.48246
172 4N02 FNR 0.0007729 0.42062 5.60224
173 2IYG FMN 0.0006721 0.4486 5.64516
174 4C25 13P 0.00007077 0.42529 5.66038
175 1DXY NAD 0.002107 0.42743 5.70571
176 2QIA U20 0.001866 0.40885 5.72519
177 2Y6Q I7T 0.01761 0.43445 5.77889
178 3EAU PDN 0.0000007723 0.53828 5.8104
179 3EAU NDP 0.0000007723 0.53828 5.8104
180 4GQB 0XU 0.00003248 0.46442 5.81395
181 2GJ3 FAD 0.0002496 0.41197 5.83333
182 4HE2 AMP 0.000009316 0.45417 5.91716
183 2DQU CPD 0.03185 0.40025 5.93607
184 2V5E SCR 0.03932 0.42043 5.94059
185 4FR3 LYS ARG ARG LYS SEP VAL 0.001234 0.42541 5.98291
186 4FR3 0V4 0.001328 0.42435 5.98291
187 1NVV GNP 0.0000406 0.46334 6.0241
188 1NVU GTP 0.000181 0.44254 6.0241
189 1QCA FUA 0.0006593 0.43165 6.10329
190 3QVL 5HY 0.0001418 0.44309 6.12245
191 1S4M LUM 0.034 0.4001 6.14334
192 1JCM 137 0.0004286 0.40287 6.17761
193 3O03 NAP 0.00006261 0.4592 6.18557
194 1H6W SER LEU ASN TYR ILE ILE LYS VAL LYS GLU 0.000111 0.44495 6.41026
195 2QM9 TDZ 0.02093 0.40366 6.45161
196 1F8F NAD 0.00001098 0.48153 6.469
197 1A5Z NAD 0.0001089 0.44366 6.58307
198 1A5Z FBP 0.0000171 0.40888 6.58307
199 1RSD PSB 0.001886 0.45125 6.61157
200 3FSJ D7K 0.0003145 0.44446 6.62768
201 2E1A MSE 0.008588 0.4133 6.66667
202 4U36 TNR 0.00008245 0.41246 6.66667
203 2TOH HBI 0.00001641 0.43161 6.70554
204 1FNZ A2G 0.0000395 0.41498 6.75105
205 3ZPG 5GP 0.0188 0.43072 6.80628
206 1Z34 2FD 0.003039 0.40087 6.80851
207 2BGM NAJ 0.00006439 0.45881 6.83453
208 2BGM MAX 0.0001701 0.40131 6.83453
209 3V91 UPG 0.000055 0.45297 6.87285
210 1I9G SAM 0.00001982 0.46454 7.14286
211 3P3N AKG 0.002472 0.45382 7.16332
212 2WA4 069 0.008159 0.40556 7.16332
213 1MXI SAH 0.002279 0.41064 7.5
214 4EKV BTN 0.00002309 0.44603 7.54717
215 2A0W DIH 0.0002567 0.41601 7.61246
216 3ZZS TRP 0.0002394 0.41897 7.69231
217 2X34 UQ8 0.01415 0.4388 7.73481
218 1MH5 HAL 0.004897 0.44037 7.76256
219 1EDO NAP 0.0002487 0.44785 7.78689
220 2X32 OTP 0.0186 0.43234 7.82123
221 3UXL CFI 0.000004721 0.47861 7.8329
222 4AP9 1PS 0.00001582 0.41499 7.9602
223 3FPZ AHZ 0.0003597 0.44796 7.97546
224 2B9W FAD 0.01719 0.44096 8.01887
225 1RP0 AHZ 0.0001956 0.4513 8.09859
226 4LTN NAI 0.00004703 0.4551 8.12183
227 4LTN FMN 0.00004432 0.45132 8.12183
228 1K97 CIR 0.01815 0.42571 8.13187
229 1K97 ASP 0.01815 0.42571 8.13187
230 1BDB NAD 0.0003222 0.44554 8.30325
231 1I1Q TRP 0.006386 0.41233 8.33333
232 2PR5 FMN 0.0021 0.4119 8.33333
233 1OTH PAO 0.0002331 0.41509 8.41121
234 4G1V FAD 0.000006799 0.5156 8.5213
235 2WL9 MBD 0.00004942 0.41713 8.52459
236 4G87 UD1 0.001106 0.41067 8.58283
237 3HU3 AGS 0.0005208 0.43275 8.58896
238 3AIQ HBO 0.0008597 0.4126 8.96686
239 4KS1 2H8 0.0001027 0.44006 8.97436
240 1UGX GAL MGC 0.00003952 0.43254 9.02256
241 1G7V PAI 0.0004247 0.41654 9.15493
242 2PN6 GLN 0.000006068 0.5031 9.33333
243 2FH5 GTP 0.00008643 0.44237 9.34579
244 1OD6 PNS 0.002131 0.40576 9.375
245 3UC5 ATP 0.00009133 0.45482 9.55414
246 1EXB NDP 0.00003284 0.47863 9.70874
247 1RZM PEP 0.01045 0.41433 9.76331
248 1RZM E4P 0.03448 0.40539 9.76331
249 1O7N IND 0.00009736 0.40612 9.79381
250 3AD8 FAD 0.04038 0.4257 9.90099
251 3E8T UQ8 0.03685 0.42119 10
252 3M0J OAF 0.000006546 0.45862 10.0977
253 3FW3 ETS 0.01603 0.40605 10.1504
254 1C1L GAL BGC 0.04281 0.40078 10.219
255 3HPF GAE 0.0002015 0.42119 10.2302
256 3F81 STT 0.01248 0.44003 10.3825
257 1ML4 PAL 0.000009116 0.42069 10.3896
258 2HMT NAI 0.001128 0.41182 10.4167
259 2RHW C0E 0.0000535 0.46501 10.6007
260 3FSY SCA 0.0006877 0.40723 10.8434
261 2ET1 GLV 0.0000005715 0.50195 10.9453
262 1OFH ADP 0.00007754 0.45712 10.9677
263 4KCF AKM 0.00001541 0.47256 11.4537
264 4KCF FMN 0.00003446 0.44686 11.4537
265 1WKL ADP 0.00005203 0.44673 11.6788
266 1WKL ATP 0.0001849 0.43944 11.6788
267 3OIG NAD 0.00002176 0.47592 12.0301
268 3OIG IMJ 0.0001204 0.42496 12.0301
269 4FUA PGH 0.00001179 0.45616 12.093
270 4CO3 ATP 0.0007864 0.41225 12.5
271 3QXV MTX 0.01562 0.40475 12.6984
272 4F8L GAL 0.01701 0.44886 13.1034
273 4F4S EFO 0.01527 0.40714 13.1579
274 1WUB OTP 0.03921 0.41137 13.4831
275 3KV8 FAH 0.02956 0.42917 14.3885
276 3MB5 SAM 0.00003774 0.46027 14.902
277 4Q0P 0MK 0.001605 0.43255 15.7692
278 4IAE 1DX 0.0005642 0.42269 16.4021
279 2BTO GTP 0.00108 0.40311 16.6667
280 2Q37 3AL 0.009524 0.42114 17.1271
281 1N07 FMN 0.03275 0.40689 17.1779
282 2WIC GNP 0.00007806 0.41111 17.603
283 3L9R L9R 0.005921 0.45048 18.3673
284 3L9R L9Q 0.008773 0.4381 18.3673
285 2FWP CIT 0.00009923 0.42436 19.1257
286 2FWP ICR 0.000243 0.41878 19.1257
287 3G08 FEE 0.009241 0.45366 20.202
288 1UQX MMA 0.00001828 0.42923 22.1239
289 1NCQ W11 0.009253 0.41791 25
Pocket No.: 2; Query (leader) PDB : 2Z5Y; Ligand: HRM; Similar sites found: 35
This union binding pocket(no: 2) in the query (biounit: 2z5y.bio1) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5GT9 NAP 0.03106 0.40699 1.90114
2 5JKG 6LF 0.0443 0.40398 1.92926
3 5IXG OTP 0.04545 0.41031 2.36686
4 4WHZ 3NL 0.04492 0.41137 2.5974
5 5VC5 96M 0.03372 0.40028 2.76817
6 5N87 N66 0.01774 0.42314 2.8754
7 4ZU4 4TG 0.01305 0.40663 3.37838
8 4ITH RCM 0.0184 0.4048 3.40136
9 1OPK P16 0.01609 0.42076 3.43434
10 1M15 ARG 0.03306 0.40775 3.64146
11 1M15 ADP 0.03306 0.40775 3.64146
12 5DEY 59T 0.04637 0.40194 3.7037
13 5FLJ QUE 0.008254 0.42398 3.76344
14 2FR6 CTN 0.04808 0.40653 4.10959
15 2QZ3 XYP XYP XYP 0.0196 0.4051 4.32432
16 5HA0 LTD 0.004888 0.44196 4.48718
17 1NHZ 486 0.02995 0.42259 4.64286
18 5DQ8 FLF 0.01932 0.40854 5.83333
19 5W4W 9WG 0.01384 0.42416 6.0423
20 4Q0L V14 0.03131 0.40063 6.46388
21 3MTX PGT 0.02218 0.41468 6.62252
22 2GJ5 VD3 0.03585 0.40893 8.02469
23 5J8O 6GZ 0.005418 0.42536 8.06452
24 4X6F 3XU 0.04381 0.40611 9.52381
25 3TAY MN0 0.0149 0.41579 9.81595
26 3AD8 PYC 0.04038 0.4257 9.90099
27 3G5D 1N1 0.03814 0.4168 11.1888
28 4UWJ MYA 0.01985 0.44137 11.5479
29 4UWJ 7L5 0.01985 0.44137 11.5479
30 4TW7 37K 0.03191 0.40021 11.7188
31 4XSH NAI 0.02345 0.40425 12.2905
32 5T2Z 017 0.031 0.40469 13.1313
33 5IXH OTP 0.02012 0.42707 13.6646
34 4YHQ G10 0.03161 0.40879 16.1616
35 2I0D MUT 0.03556 0.42711 20.202
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