Receptor
PDB id Resolution Class Description Source Keywords
2Z5Y 2.17 Å EC: 1.4.3.4 CRYSTAL STRUCTURE OF HUMAN MONOAMINE OXIDASE A (G110A) WITH HARMINE HOMO SAPIENS HUMAN MONOAMINE OXIDASE A MUTANT G110A FAD HARMINE DIMETHYLDECYLPHOSPHINE OXIDE SINGLE HELIX TRANS-MEMBRANE PROTEIN ACETYLATION CATECHOLAMINE METABOLISM FLAVOPROTEIN MITOCHONDRION NEUROTRANSMITTER DEGRADATION OXIDOREDUCTASE POLYMORPHISM TRANSMEMBRANE
Ref.: STRUCTURE OF HUMAN MONOAMINE OXIDASE A AT 2.2-A RESOLUTION: THE CONTROL OF OPENING THE ENTRY FOR SUBSTRATES/INHIBITORS PROC.NATL.ACAD.SCI.USA V. 105 5739 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DCX A:1;
A:2;
 Invalid;
Invalid;
 none;
none;
 submit data
218.316 C12 H27 O P CCCCC...
FAD A:600;
 Invalid;
 none;
 submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
HRM A:700;
 Valid;
 none;
 submit data
212.247 C13 H12 N2 O Cc1c2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2Z5Y 2.17 Å EC: 1.4.3.4 CRYSTAL STRUCTURE OF HUMAN MONOAMINE OXIDASE A (G110A) WITH HARMINE HOMO SAPIENS HUMAN MONOAMINE OXIDASE A MUTANT G110A FAD HARMINE DIMETHYLDECYLPHOSPHINE OXIDE SINGLE HELIX TRANS-MEMBRANE PROTEIN ACETYLATION CATECHOLAMINE METABOLISM FLAVOPROTEIN MITOCHONDRION NEUROTRANSMITTER DEGRADATION OXIDOREDUCTASE POLYMORPHISM TRANSMEMBRANE
Ref.: STRUCTURE OF HUMAN MONOAMINE OXIDASE A AT 2.2-A RESOLUTION: THE CONTROL OF OPENING THE ENTRY FOR SUBSTRATES/INHIBITORS PROC.NATL.ACAD.SCI.USA V. 105 5739 2008
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 2Z5Y - HRM C13 H12 N2 O Cc1c2c(ccn....
2 2Z5X - HRM C13 H12 N2 O Cc1c2c(ccn....
70% Homology Family (24)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2Z5Y - HRM C13 H12 N2 O Cc1c2c(ccn....
2 2Z5X - HRM C13 H12 N2 O Cc1c2c(ccn....
3 2BK3 Ki = 2.3 uM FOF C15 H26 O CC(=CCC/C(....
4 1OJA Ki = 3 uM ISN C8 H5 N O2 c1ccc2c(c1....
5 2XFO Ki = 58 uM XCG C11 H8 N2 O c1ccc2c(c1....
6 1OJ9 Ki = 35 uM 1PB C16 H16 c1ccc(cc1)....
7 6FW0 Ki = 17 nM E92 C16 H10 Cl N O3 c1ccc2c(c1....
8 2XCG Kd = 9 nM XCG C11 H8 N2 O c1ccc2c(c1....
9 3PO7 Ki = 3.1 uM ZON C8 H8 N2 O3 S c1ccc2c(c1....
10 2BK5 Ki = 3 uM ISN C8 H5 N O2 c1ccc2c(c1....
11 2V5Z Ki = 0.45 uM SAG C17 H17 F N2 O2 C[C@@H](C(....
12 2XFN Ki = 8.3 uM XCG C11 H8 N2 O c1ccc2c(c1....
13 3ZYX Ki = 0.143 uM MBT C16 H18 N3 S CN(C)c1ccc....
14 2C67 Ki = 17 uM RM1 C10 H13 N CN[C@@H]1C....
15 2C70 - PNZ C7 H8 N2 O2 c1cc(ccc1C....
16 4A79 Ki = 0.5 uM P1B C19 H20 N2 O3 S CCc1ccc(nc....
17 4A7A Ki = 4.2 uM RGZ C18 H19 N3 O3 S CN(CCOc1cc....
18 2V61 Ki = 0.1 uM C18 C18 H16 Cl N O3 CNCC1=CC(=....
19 2XFP - ISN C8 H5 N O2 c1ccc2c(c1....
20 2V60 Ki = 0.4 uM C17 C17 H11 Cl O4 c1cc(cc(c1....
21 6YT2 Ki = 0.31 uM PJW C12 H8 I c1ccc2c(c1....
22 6FWC Ki = 31 nM E98 C16 H10 F N O3 c1ccc2c(c1....
23 6FVZ Ki = 55 nM E8Z C18 H15 N O3 Cc1ccc(cc1....
24 2XFQ - XCG C11 H8 N2 O c1ccc2c(c1....
50% Homology Family (24)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2Z5Y - HRM C13 H12 N2 O Cc1c2c(ccn....
2 2Z5X - HRM C13 H12 N2 O Cc1c2c(ccn....
3 2BK3 Ki = 2.3 uM FOF C15 H26 O CC(=CCC/C(....
4 1OJA Ki = 3 uM ISN C8 H5 N O2 c1ccc2c(c1....
5 2XFO Ki = 58 uM XCG C11 H8 N2 O c1ccc2c(c1....
6 1OJ9 Ki = 35 uM 1PB C16 H16 c1ccc(cc1)....
7 6FW0 Ki = 17 nM E92 C16 H10 Cl N O3 c1ccc2c(c1....
8 2XCG Kd = 9 nM XCG C11 H8 N2 O c1ccc2c(c1....
9 3PO7 Ki = 3.1 uM ZON C8 H8 N2 O3 S c1ccc2c(c1....
10 2BK5 Ki = 3 uM ISN C8 H5 N O2 c1ccc2c(c1....
11 2V5Z Ki = 0.45 uM SAG C17 H17 F N2 O2 C[C@@H](C(....
12 2XFN Ki = 8.3 uM XCG C11 H8 N2 O c1ccc2c(c1....
13 3ZYX Ki = 0.143 uM MBT C16 H18 N3 S CN(C)c1ccc....
14 2C67 Ki = 17 uM RM1 C10 H13 N CN[C@@H]1C....
15 2C70 - PNZ C7 H8 N2 O2 c1cc(ccc1C....
16 4A79 Ki = 0.5 uM P1B C19 H20 N2 O3 S CCc1ccc(nc....
17 4A7A Ki = 4.2 uM RGZ C18 H19 N3 O3 S CN(CCOc1cc....
18 2V61 Ki = 0.1 uM C18 C18 H16 Cl N O3 CNCC1=CC(=....
19 2XFP - ISN C8 H5 N O2 c1ccc2c(c1....
20 2V60 Ki = 0.4 uM C17 C17 H11 Cl O4 c1cc(cc(c1....
21 6YT2 Ki = 0.31 uM PJW C12 H8 I c1ccc2c(c1....
22 6FWC Ki = 31 nM E98 C16 H10 F N O3 c1ccc2c(c1....
23 6FVZ Ki = 55 nM E8Z C18 H15 N O3 Cc1ccc(cc1....
24 2XFQ - XCG C11 H8 N2 O c1ccc2c(c1....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: HRM; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 HRM 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: HRM; Similar ligands found: 786
No: Ligand Similarity coefficient
1 ITE 0.9753
2 6FB 0.9609
3 PRL 0.9578
4 S60 0.9560
5 BIK 0.9542
6 ZRK 0.9519
7 ZHA 0.9481
8 HBO 0.9468
9 FQX 0.9465
10 X0U 0.9458
11 AH9 0.9452
12 BGU 0.9428
13 2WU 0.9423
14 15E 0.9420
15 GNM 0.9402
16 ANC 0.9390
17 0SY 0.9390
18 DPT 0.9388
19 6QF 0.9380
20 S0D 0.9377
21 K7H 0.9368
22 S98 0.9368
23 H4B 0.9364
24 ZSP 0.9359
25 0FR 0.9359
26 XCG 0.9356
27 N91 0.9355
28 JAH 0.9349
29 CK2 0.9349
30 TCR 0.9347
31 F2W 0.9347
32 TMG 0.9340
33 1DR 0.9339
34 LR8 0.9337
35 KMY 0.9336
36 3R4 0.9331
37 4V2 0.9329
38 AN3 0.9325
39 HNT 0.9320
40 4HB 0.9310
41 1ZC 0.9308
42 JG8 0.9306
43 GO2 0.9300
44 CNI 0.9300
45 N1E 0.9300
46 3VQ 0.9299
47 MR6 0.9299
48 N0Z 0.9298
49 LUM 0.9298
50 MR4 0.9295
51 QIV 0.9294
52 HRD 0.9282
53 0UL 0.9281
54 A5H 0.9281
55 795 0.9267
56 DRG 0.9262
57 CX6 0.9259
58 2J1 0.9258
59 G14 0.9257
60 JBZ 0.9255
61 8XL 0.9254
62 0NX 0.9253
63 428 0.9252
64 4BL 0.9251
65 E1K 0.9250
66 1XS 0.9250
67 2JX 0.9248
68 RA7 0.9246
69 4AU 0.9245
70 5TY 0.9245
71 L2K 0.9245
72 L22 0.9242
73 JCZ 0.9239
74 4G2 0.9238
75 DNQ 0.9235
76 UNJ 0.9233
77 344 0.9232
78 JWS 0.9231
79 2PK 0.9226
80 JRO 0.9225
81 3QV 0.9222
82 3ZB 0.9220
83 4BY 0.9220
84 3VX 0.9219
85 2QC 0.9219
86 DT7 0.9218
87 6KT 0.9216
88 THA 0.9216
89 6P3 0.9215
90 2PV 0.9214
91 7AP 0.9213
92 JP2 0.9212
93 X48 0.9203
94 5GV 0.9197
95 28A 0.9191
96 2LW 0.9191
97 BPY 0.9190
98 833 0.9189
99 FF2 0.9188
100 E3X 0.9186
101 BZE 0.9182
102 KLE 0.9177
103 YE6 0.9174
104 E7S 0.9173
105 BPU 0.9172
106 AH6 0.9172
107 2D2 0.9170
108 Y3L 0.9170
109 SWX 0.9167
110 EN1 0.9166
111 PUE 0.9165
112 BP7 0.9164
113 F02 0.9163
114 X11 0.9160
115 AH3 0.9159
116 FDR 0.9159
117 4CN 0.9159
118 3J8 0.9158
119 GJP 0.9157
120 KLS 0.9157
121 FHV 0.9156
122 ANF 0.9156
123 AA 0.9156
124 B1J 0.9155
125 FCD 0.9154
126 J38 0.9154
127 MSR 0.9154
128 X0W 0.9153
129 4RU 0.9152
130 B21 0.9152
131 BQ2 0.9151
132 3VS 0.9149
133 6ZW 0.9145
134 1HN 0.9140
135 5E5 0.9139
136 ZZA 0.9138
137 0XT 0.9136
138 GNV 0.9129
139 JTA 0.9127
140 6MW 0.9127
141 D3G 0.9126
142 4FF 0.9125
143 VC3 0.9125
144 FC2 0.9125
145 ZRL 0.9124
146 CPZ 0.9124
147 HHS 0.9123
148 WS7 0.9122
149 2FX 0.9120
150 ODK 0.9119
151 N2M 0.9119
152 KLV 0.9118
153 WS6 0.9115
154 AJY 0.9115
155 BZJ 0.9113
156 RGK 0.9111
157 JMG 0.9111
158 BHS 0.9110
159 68A 0.9108
160 A5Q 0.9106
161 OQC 0.9104
162 78Y 0.9103
163 4I8 0.9103
164 KF5 0.9102
165 OCZ 0.9102
166 1FE 0.9099
167 5WT 0.9099
168 5LA 0.9097
169 M78 0.9097
170 2FQ 0.9096
171 GNY 0.9095
172 NAG 0.9095
173 5TT 0.9094
174 U13 0.9093
175 363 0.9092
176 IOP 0.9091
177 8G6 0.9091
178 9BF 0.9089
179 GVY 0.9089
180 ZEA 0.9088
181 9CA 0.9088
182 ALE 0.9088
183 KW8 0.9085
184 8CC 0.9085
185 MR5 0.9084
186 GOE 0.9084
187 801 0.9081
188 7FU 0.9081
189 NKI 0.9080
190 FZM 0.9078
191 V1T 0.9078
192 AJG 0.9077
193 1IT 0.9077
194 18E 0.9073
195 26C 0.9073
196 1A7 0.9070
197 H4E 0.9069
198 6SD 0.9069
199 9KZ 0.9066
200 NDD 0.9065
201 ZME 0.9065
202 BMZ 0.9063
203 K44 0.9062
204 3D1 0.9061
205 9R5 0.9061
206 NRA 0.9060
207 IDZ 0.9058
208 LFN 0.9055
209 GZ2 0.9053
210 4XF 0.9052
211 9FL 0.9050
212 F4K 0.9048
213 1VK 0.9048
214 1Z6 0.9047
215 J1K 0.9047
216 CXH 0.9045
217 9UL 0.9042
218 BIO 0.9041
219 8MO 0.9041
220 4ZF 0.9041
221 F4E 0.9039
222 IQZ 0.9039
223 2K8 0.9038
224 K97 0.9037
225 CR4 0.9037
226 OLU 0.9036
227 YE7 0.9036
228 30G 0.9035
229 DDU 0.9035
230 549 0.9034
231 LOT 0.9033
232 5XL 0.9033
233 D9Z 0.9030
234 IWT 0.9028
235 27B 0.9028
236 WUB 0.9022
237 MXD 0.9021
238 27M 0.9019
239 II4 0.9019
240 WLH 0.9018
241 AES 0.9017
242 CH9 0.9016
243 F40 0.9015
244 EQA 0.9014
245 AMR 0.9014
246 52F 0.9013
247 I2E 0.9013
248 FBC 0.9012
249 DAH 0.9010
250 0OK 0.9010
251 Q9T 0.9010
252 FYR 0.9010
253 D2G 0.9009
254 5AD 0.9008
255 5SJ 0.9008
256 L03 0.9004
257 VUP 0.9004
258 RHN 0.9004
259 1V1 0.9003
260 SNU 0.9003
261 TJM 0.9003
262 8D6 0.9000
263 1FL 0.8998
264 BBY 0.8997
265 DFL 0.8996
266 JF8 0.8996
267 D8Q 0.8993
268 DUR 0.8993
269 P4L 0.8990
270 A7H 0.8989
271 2P3 0.8989
272 9OF 0.8987
273 20D 0.8986
274 3D3 0.8984
275 PIQ 0.8984
276 KTJ 0.8984
277 MMJ 0.8981
278 0JD 0.8980
279 F18 0.8979
280 0K7 0.8978
281 CTE 0.8978
282 M3E 0.8977
283 ZYQ 0.8977
284 L1T 0.8977
285 120 0.8977
286 SLS 0.8976
287 CZ0 0.8976
288 5GT 0.8973
289 GO8 0.8973
290 5VU 0.8972
291 1KP 0.8971
292 6H2 0.8970
293 36Y 0.8970
294 JY4 0.8969
295 3D8 0.8968
296 4GU 0.8968
297 X2M 0.8967
298 IQ5 0.8967
299 ZEC 0.8966
300 AGI 0.8965
301 15N 0.8965
302 C9E 0.8965
303 8NB 0.8965
304 M83 0.8964
305 GVI 0.8964
306 A73 0.8964
307 LL1 0.8962
308 WSD 0.8962
309 C53 0.8961
310 8NX 0.8961
311 MD6 0.8961
312 HX4 0.8961
313 92G 0.8960
314 JGB 0.8959
315 EZL 0.8958
316 5F8 0.8958
317 4UM 0.8957
318 K3D 0.8957
319 JYB 0.8956
320 A5E 0.8955
321 FHC 0.8955
322 Z21 0.8955
323 E1T 0.8953
324 47V 0.8951
325 MUX 0.8950
326 0NJ 0.8949
327 ENO 0.8949
328 9CE 0.8948
329 NK5 0.8948
330 1AJ 0.8946
331 C82 0.8945
332 QBP 0.8945
333 EQU 0.8943
334 WV7 0.8943
335 2JK 0.8942
336 4AB 0.8940
337 39Z 0.8940
338 Q0K 0.8940
339 ERZ 0.8939
340 TRP 0.8937
341 A9B 0.8935
342 A63 0.8935
343 UN9 0.8934
344 DX7 0.8932
345 DCZ 0.8931
346 XYS XYP 0.8930
347 HHR 0.8930
348 EMO 0.8929
349 ZYR 0.8929
350 HBI 0.8928
351 H2B 0.8928
352 THM 0.8926
353 RDT 0.8925
354 J6W 0.8925
355 5OR 0.8925
356 PQM 0.8923
357 PH2 0.8923
358 FER 0.8922
359 CDY 0.8922
360 5B2 0.8921
361 DXK 0.8920
362 0FK 0.8919
363 EV2 0.8918
364 RSV 0.8917
365 MUK 0.8916
366 4YO 0.8914
367 YZ9 0.8913
368 DT9 0.8913
369 6TJ 0.8912
370 TIY 0.8911
371 NEO 0.8909
372 NEU 0.8908
373 BA5 0.8908
374 2J2 0.8906
375 H5B 0.8905
376 KYN 0.8904
377 1QV 0.8903
378 PJW 0.8903
379 SJK 0.8903
380 C4E 0.8903
381 KU1 0.8903
382 0BP 0.8902
383 SG2 0.8902
384 X6W 0.8902
385 GF4 0.8902
386 0LO 0.8900
387 8W9 0.8898
388 27K 0.8898
389 TID 0.8897
390 X0T 0.8897
391 5V7 0.8896
392 CSN 0.8895
393 GNJ 0.8894
394 CHQ 0.8893
395 KTW 0.8891
396 ESX 0.8891
397 2QU 0.8890
398 5H6 0.8887
399 SNO 0.8887
400 7VP 0.8886
401 F5C 0.8885
402 774 0.8884
403 ARP 0.8884
404 3N0 0.8884
405 122 0.8883
406 S0E 0.8882
407 2GQ 0.8882
408 DNA 0.8882
409 9ZE 0.8882
410 657 0.8880
411 DHC 0.8880
412 8ZE 0.8880
413 B98 0.8879
414 JA5 0.8879
415 0DF 0.8878
416 L15 0.8874
417 PEY 0.8874
418 272 0.8874
419 TZF 0.8873
420 5TZ 0.8872
421 CIY 0.8872
422 BZ2 0.8870
423 B2E 0.8870
424 SZ5 0.8870
425 28B 0.8869
426 7MW 0.8868
427 G6P 0.8867
428 AVX 0.8865
429 3L1 0.8865
430 LR2 0.8864
431 ROI 0.8862
432 124 0.8861
433 RKV 0.8861
434 4HG 0.8860
435 92P 0.8860
436 7ME 0.8859
437 4BX 0.8859
438 3Y7 0.8858
439 H70 0.8857
440 CTD 0.8854
441 BNL 0.8854
442 9NB 0.8853
443 EST 0.8853
444 P7V 0.8853
445 KWV 0.8851
446 8HC 0.8851
447 V2Z 0.8851
448 TXQ 0.8847
449 M3F 0.8847
450 LO1 0.8846
451 7O4 0.8845
452 6X9 0.8844
453 7G2 0.8843
454 KJU 0.8841
455 397 0.8841
456 9JT 0.8840
457 ADL 0.8840
458 ESP 0.8839
459 N4E 0.8838
460 G12 0.8838
461 1EB 0.8837
462 N2I 0.8836
463 PPY 0.8834
464 3F4 0.8833
465 7EH 0.8830
466 TT4 0.8830
467 PE2 0.8830
468 TIA 0.8829
469 NE2 0.8828
470 3XR 0.8827
471 MPV 0.8827
472 25F 0.8826
473 KDV 0.8824
474 EES 0.8823
475 SDN 0.8822
476 EUE 0.8822
477 6ZE 0.8822
478 I3E 0.8821
479 VXX 0.8821
480 SKF 0.8821
481 DK1 0.8820
482 DX3 0.8820
483 492 0.8820
484 S7D 0.8819
485 HA5 0.8819
486 5VL 0.8819
487 ICB 0.8818
488 4LW 0.8816
489 55D 0.8816
490 AQN 0.8815
491 ESI 0.8814
492 M4N 0.8814
493 1EL 0.8810
494 P9E 0.8809
495 PH3 0.8808
496 5RO 0.8807
497 BVA 0.8807
498 UAY 0.8807
499 LJ3 0.8806
500 7FZ 0.8805
501 M4E 0.8805
502 61M 0.8803
503 GDL 0.8803
504 0LA 0.8803
505 A6W 0.8803
506 AY4 0.8802
507 7MX 0.8801
508 A6Z 0.8800
509 MQN 0.8800
510 UKV 0.8800
511 LQ2 0.8799
512 0TU 0.8799
513 XYP XYP 0.8795
514 SU9 0.8794
515 5S9 0.8793
516 1YL 0.8793
517 AR3 0.8792
518 5GU 0.8792
519 CKA 0.8790
520 YTX 0.8787
521 M1Z 0.8787
522 6RQ 0.8786
523 5FL 0.8785
524 FMQ 0.8785
525 D1G 0.8784
526 GZV 0.8784
527 36M 0.8784
528 R9Y 0.8784
529 PMP 0.8784
530 A7N 0.8780
531 N7I 0.8779
532 8V8 0.8779
533 R20 0.8779
534 GEN 0.8779
535 57D 0.8777
536 B23 0.8777
537 1V4 0.8776
538 4JQ 0.8776
539 WG8 0.8776
540 MUR 0.8773
541 PLP 0.8770
542 RNO 0.8770
543 XI7 0.8770
544 5ER 0.8769
545 537 0.8768
546 0W1 0.8768
547 CCV 0.8768
548 4FC 0.8767
549 80G 0.8767
550 1Q1 0.8764
551 6NT 0.8764
552 DX2 0.8762
553 AJ1 0.8760
554 N8Y 0.8759
555 245 0.8757
556 8UY 0.8757
557 4NB 0.8756
558 0HN 0.8755
559 JAW 0.8755
560 BX4 0.8754
561 ADN 0.8753
562 72D 0.8753
563 4FE 0.8752
564 DX1 0.8752
565 4BZ 0.8750
566 S62 0.8750
567 LDC 0.8750
568 GNG 0.8747
569 J3Z 0.8746
570 EWG 0.8746
571 K4V 0.8745
572 68C 0.8744
573 RYV 0.8744
574 IS2 0.8743
575 5QY 0.8743
576 3C5 0.8741
577 5NN 0.8740
578 MFR 0.8740
579 54X 0.8740
580 39O 0.8739
581 YZM 0.8739
582 M6Z 0.8739
583 IA2 0.8737
584 4MB 0.8737
585 PNZ 0.8735
586 EXD 0.8735
587 HJ7 0.8734
588 6FZ 0.8730
589 92O 0.8729
590 2HC 0.8728
591 B56 0.8728
592 4TU 0.8727
593 0HO 0.8727
594 3NY 0.8727
595 CC6 0.8726
596 FNT 0.8725
597 CUE 0.8724
598 GJK 0.8721
599 1F1 0.8721
600 IBP 0.8720
601 UFO 0.8718
602 38E 0.8717
603 HQJ 0.8717
604 BVS 0.8716
605 5TU 0.8716
606 9TF 0.8715
607 6DQ 0.8714
608 AWE 0.8714
609 6TZ 0.8713
610 1V3 0.8710
611 121 0.8709
612 B62 0.8709
613 OQR 0.8709
614 AJV 0.8708
615 4MU 0.8707
616 3W8 0.8706
617 SYV 0.8706
618 ALR 0.8704
619 K68 0.8703
620 4NP 0.8703
621 6ME 0.8702
622 LEL 0.8702
623 6VW 0.8701
624 ANN 0.8701
625 VM1 0.8699
626 A29 0.8699
627 D48 0.8698
628 QX4 0.8697
629 IPD 0.8697
630 L5V 0.8696
631 9FH 0.8695
632 2UD 0.8695
633 4F8 0.8694
634 QMR 0.8694
635 3PF 0.8693
636 2ZM 0.8693
637 6L6 0.8693
638 EAE 0.8692
639 W81 0.8690
640 JVD 0.8690
641 60L 0.8689
642 JDN 0.8685
643 K37 0.8684
644 K25 0.8684
645 AO 0.8683
646 3WL 0.8682
647 QBS 0.8682
648 NDG 0.8682
649 3JC 0.8681
650 TR4 0.8681
651 JB8 0.8681
652 AP6 0.8679
653 UA2 0.8679
654 259 0.8676
655 IIH 0.8675
656 8M5 0.8675
657 2HU 0.8675
658 TGX 0.8675
659 DBS 0.8675
660 IAC 0.8674
661 5SD 0.8673
662 6BK 0.8672
663 B0K 0.8671
664 P4T 0.8670
665 3A9 0.8669
666 36E 0.8669
667 BGP 0.8669
668 NE1 0.8668
669 M5H 0.8668
670 4Z1 0.8668
671 78U 0.8668
672 CWJ 0.8667
673 CLZ 0.8667
674 0FO 0.8666
675 JU2 0.8665
676 1OT 0.8664
677 19E 0.8663
678 2QV 0.8662
679 9FE 0.8662
680 IOS 0.8662
681 IL5 0.8661
682 64E 0.8660
683 LR5 0.8660
684 AOY 0.8659
685 802 0.8656
686 44V 0.8656
687 H35 0.8655
688 1WO 0.8655
689 EVF 0.8654
690 J5I 0.8653
691 DQU 0.8653
692 6NI 0.8652
693 8WO 0.8651
694 MVN 0.8650
695 MS9 0.8648
696 0N7 0.8647
697 KYA 0.8647
698 6E8 0.8646
699 TRU 0.8646
700 5NI 0.8645
701 3AE 0.8645
702 8SK 0.8644
703 SE2 0.8643
704 A5P 0.8643
705 4NZ 0.8643
706 NIF 0.8643
707 97K 0.8642
708 G3E 0.8640
709 D25 0.8634
710 0FN 0.8634
711 JF1 0.8632
712 9AP 0.8631
713 9FG 0.8630
714 NOM 0.8630
715 LLT 0.8629
716 56D 0.8629
717 DNF 0.8629
718 OTW 0.8628
719 XHP 0.8626
720 0J5 0.8625
721 SRO 0.8621
722 2O6 0.8620
723 28N 0.8620
724 HQD 0.8619
725 P80 0.8617
726 FLF 0.8617
727 0F9 0.8615
728 CUH 0.8613
729 7D7 0.8612
730 RVE 0.8612
731 PK3 0.8611
732 HH6 0.8610
733 XYS XYS 0.8610
734 HC8 0.8610
735 FUD 0.8610
736 72G 0.8609
737 E9S 0.8609
738 62D 0.8608
739 2BG 0.8606
740 LFQ 0.8604
741 092 0.8601
742 TWO 0.8600
743 A8D 0.8599
744 1L5 0.8598
745 0SX 0.8598
746 17M 0.8597
747 GXD 0.8597
748 JR2 0.8597
749 E5X 0.8597
750 7I2 0.8596
751 44W 0.8595
752 K48 0.8593
753 PCQ 0.8592
754 5ID 0.8592
755 XM5 0.8591
756 MAJ 0.8587
757 U14 0.8585
758 6FG 0.8584
759 LDR 0.8581
760 1V8 0.8579
761 HNM 0.8576
762 0XR 0.8576
763 PO6 0.8574
764 3GX 0.8573
765 3Q0 0.8571
766 KMP 0.8570
767 MS0 0.8570
768 DHT 0.8569
769 4CM 0.8568
770 GVG 0.8563
771 LI7 0.8562
772 4NS 0.8562
773 ONR 0.8560
774 KP2 0.8556
775 613 0.8555
776 2PW 0.8553
777 BIH 0.8548
778 NWD 0.8547
779 E6Q 0.8543
780 LP8 0.8541
781 GB5 0.8534
782 ASD 0.8528
783 RD4 0.8524
784 1M2 0.8520
785 JF2 0.8511
786 4ME 0.8508
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2Z5Y; Ligand: HRM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2z5y.bio2) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 2Z5Y; Ligand: HRM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2z5y.bio2) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 2Z5Y; Ligand: HRM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 2z5y.bio2) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 2Z5Y; Ligand: HRM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 2z5y.bio2) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 2Z5Y; Ligand: HRM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 2z5y.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback