Receptor
PDB id Resolution Class Description Source Keywords
2Z1W 1.63 Å EC: 2.4.2.29 TRNA GUANINE TRANSGLYCOSYLASE TGT E235Q MUTANT IN COMPLEX WI BUTYL-5,6-DIHYDRO-1H-IMIDAZO[4,5-D]PYRIDAZINE-4,7-DIONE) ZYMOMONAS MOBILIS TGT E235Q MUTANT BDI BIH 2-BUTYL-56-DIHYDRO-1H-IMIDAZO[D]PYRIDAZINE-47-DIONE TRANSFERASE
Ref.: GLUTAMATE VERSUS GLUTAMINE EXCHANGE SWAPS SUBSTRATE SELECTIVITY IN TRNA-GUANINE TRANSGLYCOSYLASE: INSIG THE REGULATION OF SUBSTRATE SELECTIVITY BY KINETIC CRYSTALLOGRAPHIC STUDIES J.MOL.BIOL. V. 374 764 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BDI A:600;
 Valid;
 none;
 submit data
208.217 C9 H12 N4 O2 CCCCc...
GOL A:702;
A:703;
A:705;
A:706;
A:708;
A:710;
A:715;
A:716;
A:717;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
none;
none;
none;
none;
 submit data
92.094 C3 H8 O3 C(C(C...
ZN A:500;
 Part of Protein;
 none;
 submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3GE7 1.5 Å EC: 2.4.2.29 TRNA-GUANINE TRANSGLYCOSYLASE IN COMPLEX WITH 6-AMINO-4-{2- [(CYCLOPENTYLMETHYL)AMINO]ETHYL}-2-(METHYLAMINO)-1,7-DIHYDRI MIDAZO[4,5-G]QUINAZOLIN-8-ONE ZYMOMONAS MOBILIS DRUG DESIGN TGT TIM BARREL GLYCOSYLTRANSFERASE METAL-BINDQUEUOSINE BIOSYNTHESIS TRANSFERASE TRNA PROCESSING
Ref.: HOW TO REPLACE THE RESIDUAL SOLVATION SHELL OF POLA SITE RESIDUES TO ACHIEVE NANOMOLAR INHIBITION OF TRNA-GUANINE TRANSGLYCOSYLASE CHEMMEDCHEM V. 4 2012 2009
Members (57)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1ENU Ki = 8.3 uM APZ C8 H7 N3 O2 c1cc2c(cc1....
2 2PWU - GUN C5 H5 N5 O c1[nH]c2c(....
3 4Q4S Kd = 111.6 nM S98 C14 H12 N6 O S c1cc(sc1)C....
4 2QII - PQ0 C7 H5 N5 O c1c(c2c([n....
5 1PXG - PRF C7 H9 N5 O c1c(c2c([n....
6 4KWO Ki = 353 nM 1UD C18 H24 N6 O5 CNc1[nH]c2....
7 2Z7K Ki = 77 nM BGU C9 H8 N6 O c1c2c(cc3c....
8 3SM0 Ki = 740 nM AEK C18 H24 N6 O CNc1[nH]c2....
9 6RKQ Ki = 48 uM K75 C13 H14 N6 CC#C[C@@H]....
10 4Q4P Kd = 407.4 nM 2YO C16 H20 N6 O c1c2c(cc3c....
11 1K4H Ki = 7.7 uM APQ C12 H16 N4 O S CCCSCc1cc(....
12 1EFZ - PRF C7 H9 N5 O c1c(c2c([n....
13 3C2Y Ki = 1.5 uM S60 C10 H9 N5 O Cc1[nH]c2c....
14 1Y5X Ki = 3.7 uM E89 C18 H17 N5 O2 COc1ccc(cc....
15 1R5Y Ki = 0.35 uM DQU C8 H8 N4 O c1cc2c(cc1....
16 3RR4 Ki = 28050 nM HRD C11 H12 N6 O CNc1[nH]c2....
17 3EOU Ki = 97 nM PK3 C12 H14 N6 O2 CNc1[nH]c2....
18 6FMN Kd = 1120 nM E4E C15 H18 N6 O5 CO[C@H]1[C....
19 4Q4Q Kd = 1638.9 nM SAQ C14 H11 N5 O S c1cc(sc1)C....
20 4E2V - PRF C7 H9 N5 O c1c(c2c([n....
21 2Z1X - PRF C7 H9 N5 O c1c(c2c([n....
22 5JXQ Ki = 7 nM 6OK C19 H20 N6 O2 c1cc(ccc1C....
23 1Q66 Ki = 1.7 uM KMB C16 H16 N4 O S c1ccc(cc1)....
24 1N2V Ki = 83 uM BDI C9 H12 N4 O2 CCCCc1[nH]....
25 1Y5W Ki = 6.9 uM NEZ C18 H17 N5 O Cc1ccc(cc1....
26 1Q63 Ki = 1.4 uM AIQ C12 H12 N6 O S c1cnc([nH]....
27 4PUL Kd = 146.1 nM 2WU C10 H10 N6 O CNc1[nH]c2....
28 3GC4 Ki = 25 nM AAQ C19 H21 N7 O CNc1[nH]c2....
29 4LBU Kd = 276 nM 1WJ C18 H24 N6 O5 CNc1[nH]c2....
30 6RKT Ki = 17 uM K7H C10 H12 N6 CNc1[nH]c2....
31 2Z1W - BDI C9 H12 N4 O2 CCCCc1[nH]....
32 1K4G Ki = 1.4 uM AIQ C12 H12 N6 O S c1cnc([nH]....
33 1P0E - PRF C7 H9 N5 O c1c(c2c([n....
34 4LEQ Kd = 288 nM 1WK C17 H22 N6 O5 CNc1[nH]c2....
35 1P0B - PQ0 C7 H5 N5 O c1c(c2c([n....
36 2POT - GUN C5 H5 N5 O c1[nH]c2c(....
37 2QZR Ki = 55 nM S79 C20 H16 N6 O c1ccc2c(c1....
38 4Q4O Kd = 34.3 nM 2YM C16 H21 N7 O c1c2c(cc3c....
39 3S1G Ki = 6500 nM ITE C10 H9 N5 O CNc1[nH]c2....
40 4PUM Kd = 188.1 nM 2WU C10 H10 N6 O CNc1[nH]c2....
41 1S38 Ki = 7 uM MAQ C9 H9 N3 O Cc1cccc2c1....
42 1Q65 Ki = 3.5 uM BHB C13 H19 N5 O S CN(C)CCSCc....
43 3EOS Ki = 4 nM PK2 C19 H27 N7 O CNc1[nH]c2....
44 1F3E Ki = 0.2 uM DPZ C8 H8 N4 O2 c1c(cc(c2c....
45 1Y5V Ki = 1 uM NE8 C17 H15 N5 O c1ccc(cc1)....
46 1OZQ - PRF C7 H9 N5 O c1c(c2c([n....
47 4PUJ Kd = 35 nM CKR C15 H19 N7 O2 c1c2c(cc3c....
48 2BBF Ki = 7.9 uM 344 C9 H7 N5 O c1c2c(cc3c....
49 6FPU Kd = 321 nM E48 C21 H26 N6 O6 CC1(O[C@@H....
50 1S39 Ki = 20 nM AQO C8 H7 N3 O c1ccc2c(c1....
51 3TLL Ki = 40830 nM 62D C12 H14 N6 O CCNC1=Nc2c....
52 4PUK Kd = 52.4 nM 2WU C10 H10 N6 O CNc1[nH]c2....
53 2PWV - PQ0 C7 H5 N5 O c1c(c2c([n....
54 3GC5 Ki = 55 nM 2MQ C12 H15 N7 O CNc1[nH]c2....
55 3GE7 Ki = 2 nM AFQ C18 H25 N7 O CNc1[nH]c2....
56 4Q4R Kd = 369.2 nM SQO C15 H18 N6 O2 c1c2c(cc3c....
57 1Q4W Ki = 0.35 uM DQU C8 H8 N4 O c1cc2c(cc1....
70% Homology Family (57)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1ENU Ki = 8.3 uM APZ C8 H7 N3 O2 c1cc2c(cc1....
2 2PWU - GUN C5 H5 N5 O c1[nH]c2c(....
3 4Q4S Kd = 111.6 nM S98 C14 H12 N6 O S c1cc(sc1)C....
4 2QII - PQ0 C7 H5 N5 O c1c(c2c([n....
5 1PXG - PRF C7 H9 N5 O c1c(c2c([n....
6 4KWO Ki = 353 nM 1UD C18 H24 N6 O5 CNc1[nH]c2....
7 2Z7K Ki = 77 nM BGU C9 H8 N6 O c1c2c(cc3c....
8 3SM0 Ki = 740 nM AEK C18 H24 N6 O CNc1[nH]c2....
9 6RKQ Ki = 48 uM K75 C13 H14 N6 CC#C[C@@H]....
10 4Q4P Kd = 407.4 nM 2YO C16 H20 N6 O c1c2c(cc3c....
11 1K4H Ki = 7.7 uM APQ C12 H16 N4 O S CCCSCc1cc(....
12 1EFZ - PRF C7 H9 N5 O c1c(c2c([n....
13 3C2Y Ki = 1.5 uM S60 C10 H9 N5 O Cc1[nH]c2c....
14 1Y5X Ki = 3.7 uM E89 C18 H17 N5 O2 COc1ccc(cc....
15 1R5Y Ki = 0.35 uM DQU C8 H8 N4 O c1cc2c(cc1....
16 3RR4 Ki = 28050 nM HRD C11 H12 N6 O CNc1[nH]c2....
17 3EOU Ki = 97 nM PK3 C12 H14 N6 O2 CNc1[nH]c2....
18 6FMN Kd = 1120 nM E4E C15 H18 N6 O5 CO[C@H]1[C....
19 4Q4Q Kd = 1638.9 nM SAQ C14 H11 N5 O S c1cc(sc1)C....
20 4E2V - PRF C7 H9 N5 O c1c(c2c([n....
21 2Z1X - PRF C7 H9 N5 O c1c(c2c([n....
22 5JXQ Ki = 7 nM 6OK C19 H20 N6 O2 c1cc(ccc1C....
23 1Q66 Ki = 1.7 uM KMB C16 H16 N4 O S c1ccc(cc1)....
24 1N2V Ki = 83 uM BDI C9 H12 N4 O2 CCCCc1[nH]....
25 1Y5W Ki = 6.9 uM NEZ C18 H17 N5 O Cc1ccc(cc1....
26 1Q63 Ki = 1.4 uM AIQ C12 H12 N6 O S c1cnc([nH]....
27 4PUL Kd = 146.1 nM 2WU C10 H10 N6 O CNc1[nH]c2....
28 3GC4 Ki = 25 nM AAQ C19 H21 N7 O CNc1[nH]c2....
29 4LBU Kd = 276 nM 1WJ C18 H24 N6 O5 CNc1[nH]c2....
30 6RKT Ki = 17 uM K7H C10 H12 N6 CNc1[nH]c2....
31 2Z1W - BDI C9 H12 N4 O2 CCCCc1[nH]....
32 1K4G Ki = 1.4 uM AIQ C12 H12 N6 O S c1cnc([nH]....
33 1P0E - PRF C7 H9 N5 O c1c(c2c([n....
34 4LEQ Kd = 288 nM 1WK C17 H22 N6 O5 CNc1[nH]c2....
35 1P0B - PQ0 C7 H5 N5 O c1c(c2c([n....
36 2POT - GUN C5 H5 N5 O c1[nH]c2c(....
37 2QZR Ki = 55 nM S79 C20 H16 N6 O c1ccc2c(c1....
38 4Q4O Kd = 34.3 nM 2YM C16 H21 N7 O c1c2c(cc3c....
39 3S1G Ki = 6500 nM ITE C10 H9 N5 O CNc1[nH]c2....
40 4PUM Kd = 188.1 nM 2WU C10 H10 N6 O CNc1[nH]c2....
41 1S38 Ki = 7 uM MAQ C9 H9 N3 O Cc1cccc2c1....
42 1Q65 Ki = 3.5 uM BHB C13 H19 N5 O S CN(C)CCSCc....
43 3EOS Ki = 4 nM PK2 C19 H27 N7 O CNc1[nH]c2....
44 1F3E Ki = 0.2 uM DPZ C8 H8 N4 O2 c1c(cc(c2c....
45 1Y5V Ki = 1 uM NE8 C17 H15 N5 O c1ccc(cc1)....
46 1OZQ - PRF C7 H9 N5 O c1c(c2c([n....
47 4PUJ Kd = 35 nM CKR C15 H19 N7 O2 c1c2c(cc3c....
48 2BBF Ki = 7.9 uM 344 C9 H7 N5 O c1c2c(cc3c....
49 6FPU Kd = 321 nM E48 C21 H26 N6 O6 CC1(O[C@@H....
50 1S39 Ki = 20 nM AQO C8 H7 N3 O c1ccc2c(c1....
51 3TLL Ki = 40830 nM 62D C12 H14 N6 O CCNC1=Nc2c....
52 4PUK Kd = 52.4 nM 2WU C10 H10 N6 O CNc1[nH]c2....
53 2PWV - PQ0 C7 H5 N5 O c1c(c2c([n....
54 3GC5 Ki = 55 nM 2MQ C12 H15 N7 O CNc1[nH]c2....
55 3GE7 Ki = 2 nM AFQ C18 H25 N7 O CNc1[nH]c2....
56 4Q4R Kd = 369.2 nM SQO C15 H18 N6 O2 c1c2c(cc3c....
57 1Q4W Ki = 0.35 uM DQU C8 H8 N4 O c1cc2c(cc1....
50% Homology Family (59)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1ENU Ki = 8.3 uM APZ C8 H7 N3 O2 c1cc2c(cc1....
2 2PWU - GUN C5 H5 N5 O c1[nH]c2c(....
3 4Q4S Kd = 111.6 nM S98 C14 H12 N6 O S c1cc(sc1)C....
4 2QII - PQ0 C7 H5 N5 O c1c(c2c([n....
5 1PXG - PRF C7 H9 N5 O c1c(c2c([n....
6 4KWO Ki = 353 nM 1UD C18 H24 N6 O5 CNc1[nH]c2....
7 2Z7K Ki = 77 nM BGU C9 H8 N6 O c1c2c(cc3c....
8 3SM0 Ki = 740 nM AEK C18 H24 N6 O CNc1[nH]c2....
9 6RKQ Ki = 48 uM K75 C13 H14 N6 CC#C[C@@H]....
10 4Q4P Kd = 407.4 nM 2YO C16 H20 N6 O c1c2c(cc3c....
11 1K4H Ki = 7.7 uM APQ C12 H16 N4 O S CCCSCc1cc(....
12 1EFZ - PRF C7 H9 N5 O c1c(c2c([n....
13 3C2Y Ki = 1.5 uM S60 C10 H9 N5 O Cc1[nH]c2c....
14 1Y5X Ki = 3.7 uM E89 C18 H17 N5 O2 COc1ccc(cc....
15 1R5Y Ki = 0.35 uM DQU C8 H8 N4 O c1cc2c(cc1....
16 3RR4 Ki = 28050 nM HRD C11 H12 N6 O CNc1[nH]c2....
17 3EOU Ki = 97 nM PK3 C12 H14 N6 O2 CNc1[nH]c2....
18 6FMN Kd = 1120 nM E4E C15 H18 N6 O5 CO[C@H]1[C....
19 4Q4Q Kd = 1638.9 nM SAQ C14 H11 N5 O S c1cc(sc1)C....
20 4E2V - PRF C7 H9 N5 O c1c(c2c([n....
21 2Z1X - PRF C7 H9 N5 O c1c(c2c([n....
22 5JXQ Ki = 7 nM 6OK C19 H20 N6 O2 c1cc(ccc1C....
23 1Q66 Ki = 1.7 uM KMB C16 H16 N4 O S c1ccc(cc1)....
24 1N2V Ki = 83 uM BDI C9 H12 N4 O2 CCCCc1[nH]....
25 1Y5W Ki = 6.9 uM NEZ C18 H17 N5 O Cc1ccc(cc1....
26 1Q63 Ki = 1.4 uM AIQ C12 H12 N6 O S c1cnc([nH]....
27 4PUL Kd = 146.1 nM 2WU C10 H10 N6 O CNc1[nH]c2....
28 3GC4 Ki = 25 nM AAQ C19 H21 N7 O CNc1[nH]c2....
29 4LBU Kd = 276 nM 1WJ C18 H24 N6 O5 CNc1[nH]c2....
30 6RKT Ki = 17 uM K7H C10 H12 N6 CNc1[nH]c2....
31 2Z1W - BDI C9 H12 N4 O2 CCCCc1[nH]....
32 1K4G Ki = 1.4 uM AIQ C12 H12 N6 O S c1cnc([nH]....
33 1P0E - PRF C7 H9 N5 O c1c(c2c([n....
34 4LEQ Kd = 288 nM 1WK C17 H22 N6 O5 CNc1[nH]c2....
35 1P0B - PQ0 C7 H5 N5 O c1c(c2c([n....
36 2POT - GUN C5 H5 N5 O c1[nH]c2c(....
37 2QZR Ki = 55 nM S79 C20 H16 N6 O c1ccc2c(c1....
38 4Q4O Kd = 34.3 nM 2YM C16 H21 N7 O c1c2c(cc3c....
39 3S1G Ki = 6500 nM ITE C10 H9 N5 O CNc1[nH]c2....
40 4PUM Kd = 188.1 nM 2WU C10 H10 N6 O CNc1[nH]c2....
41 1S38 Ki = 7 uM MAQ C9 H9 N3 O Cc1cccc2c1....
42 1Q65 Ki = 3.5 uM BHB C13 H19 N5 O S CN(C)CCSCc....
43 3EOS Ki = 4 nM PK2 C19 H27 N7 O CNc1[nH]c2....
44 1F3E Ki = 0.2 uM DPZ C8 H8 N4 O2 c1c(cc(c2c....
45 1Y5V Ki = 1 uM NE8 C17 H15 N5 O c1ccc(cc1)....
46 1OZQ - PRF C7 H9 N5 O c1c(c2c([n....
47 4PUJ Kd = 35 nM CKR C15 H19 N7 O2 c1c2c(cc3c....
48 2BBF Ki = 7.9 uM 344 C9 H7 N5 O c1c2c(cc3c....
49 6FPU Kd = 321 nM E48 C21 H26 N6 O6 CC1(O[C@@H....
50 1S39 Ki = 20 nM AQO C8 H7 N3 O c1ccc2c(c1....
51 3TLL Ki = 40830 nM 62D C12 H14 N6 O CCNC1=Nc2c....
52 4PUK Kd = 52.4 nM 2WU C10 H10 N6 O CNc1[nH]c2....
53 2PWV - PQ0 C7 H5 N5 O c1c(c2c([n....
54 3GC5 Ki = 55 nM 2MQ C12 H15 N7 O CNc1[nH]c2....
55 3GE7 Ki = 2 nM AFQ C18 H25 N7 O CNc1[nH]c2....
56 4Q4R Kd = 369.2 nM SQO C15 H18 N6 O2 c1c2c(cc3c....
57 1Q4W Ki = 0.35 uM DQU C8 H8 N4 O c1cc2c(cc1....
58 6H42 - GGL C5 H9 N O4 C(CC(=O)O)....
59 6H45 - QEI C12 H15 N5 O3 c1c(c2c([n....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: BDI; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 BDI 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: BDI; Similar ligands found: 278
No: Ligand Similarity coefficient
1 GO8 0.9497
2 3D3 0.9434
3 UFO 0.9371
4 7PJ 0.9348
5 6Q3 0.9313
6 8WT 0.9287
7 2KU 0.9286
8 5WT 0.9262
9 6N4 0.9251
10 KTW 0.9243
11 SNY 0.9230
12 CIY 0.9224
13 C9M 0.9215
14 ZIP 0.9207
15 FF2 0.9195
16 6HP 0.9185
17 ZEA 0.9176
18 55D 0.9164
19 C9E 0.9163
20 AC2 0.9161
21 S8D 0.9158
22 4BX 0.9158
23 FER 0.9147
24 XFE 0.9140
25 G6P 0.9134
26 ONZ 0.9132
27 N7I 0.9131
28 FSU 0.9129
29 F5C 0.9128
30 MXD 0.9124
31 7I2 0.9121
32 8W9 0.9109
33 3N0 0.9105
34 SG2 0.9097
35 SXX 0.9081
36 EGR 0.9081
37 B21 0.9078
38 NPA 0.9074
39 ZYQ 0.9071
40 GJK 0.9057
41 QUB 0.9056
42 8BD 0.9054
43 ZHA 0.9046
44 0SY 0.9045
45 X0T 0.9043
46 8Y7 0.9042
47 R9Y 0.9039
48 GI2 0.9032
49 OSB 0.9032
50 R4E 0.9027
51 WA2 0.9025
52 BGP 0.9025
53 ALE 0.9022
54 3VX 0.9019
55 EYJ 0.9015
56 DHC 0.9014
57 Q5M 0.9010
58 TMG 0.9010
59 BG6 0.9009
60 C09 0.9008
61 MBP 0.9007
62 8MP 0.9002
63 GOE 0.9002
64 K3Q 0.9000
65 D8Q 0.8999
66 9F8 0.8999
67 XQI 0.8999
68 HBI 0.8997
69 L21 0.8995
70 JND 0.8990
71 H35 0.8988
72 2FX 0.8988
73 2LT 0.8982
74 ZRK 0.8981
75 HPT 0.8979
76 D80 0.8976
77 ZRL 0.8971
78 JR2 0.8970
79 W8G 0.8965
80 I2E 0.8963
81 SYR 0.8955
82 LLG 0.8949
83 ZME 0.8947
84 MD6 0.8945
85 MPP 0.8943
86 1QV 0.8941
87 M02 0.8937
88 8NX 0.8936
89 9BF 0.8936
90 1QP 0.8930
91 XIY 0.8929
92 IOP 0.8927
93 EYV 0.8926
94 YE6 0.8924
95 DXK 0.8921
96 78P 0.8920
97 H4B 0.8919
98 EYY 0.8919
99 S0D 0.8918
100 ZYV 0.8913
101 HBO 0.8913
102 VXX 0.8913
103 PLP 0.8906
104 GI1 0.8902
105 H4E 0.8899
106 N1E 0.8898
107 XG1 0.8895
108 5WS 0.8891
109 NIP 0.8890
110 EYM 0.8887
111 M01 0.8885
112 ZYC 0.8885
113 4F8 0.8885
114 G30 0.8884
115 NBV 0.8882
116 WLH 0.8882
117 B41 0.8878
118 NIY 0.8878
119 EYA 0.8876
120 CR1 0.8876
121 7PS 0.8875
122 UAY 0.8873
123 DL6 0.8873
124 XDE 0.8871
125 KLV 0.8864
126 4ME 0.8864
127 57O 0.8859
128 B2E 0.8857
129 E35 0.8856
130 ZEZ 0.8855
131 CKU 0.8849
132 TSS 0.8844
133 GI4 0.8842
134 K37 0.8838
135 D87 0.8835
136 B23 0.8832
137 H2B 0.8832
138 5C1 0.8824
139 ELH 0.8824
140 3D8 0.8823
141 JY2 0.8820
142 NQH 0.8816
143 LJ4 0.8813
144 AZC 0.8812
145 UQ1 0.8812
146 36M 0.8812
147 EV0 0.8810
148 NW1 0.8809
149 BIO 0.8807
150 EXL 0.8806
151 A4G 0.8803
152 FCD 0.8801
153 RGG 0.8800
154 SYE 0.8797
155 Z25 0.8793
156 HA6 0.8792
157 4R1 0.8789
158 H7Y 0.8788
159 0J5 0.8787
160 NAL 0.8786
161 MUX 0.8784
162 EMZ 0.8784
163 AEH 0.8782
164 P83 0.8781
165 CMG 0.8779
166 KYN 0.8777
167 ZYW 0.8777
168 6PB 0.8775
169 0XR 0.8775
170 YE7 0.8774
171 6J5 0.8773
172 SRO 0.8773
173 PLR 0.8773
174 CHQ 0.8770
175 HVE 0.8770
176 5JT 0.8769
177 E7R 0.8769
178 7MX 0.8769
179 LOT 0.8768
180 2BG 0.8767
181 QBM 0.8765
182 5OF 0.8765
183 RUG 0.8764
184 AUY 0.8764
185 5V7 0.8760
186 67Y 0.8759
187 2LY 0.8758
188 SNV 0.8756
189 GXG 0.8755
190 GB4 0.8754
191 28S 0.8750
192 GZV 0.8743
193 L3L 0.8741
194 PMM 0.8740
195 ND5 0.8740
196 5WU 0.8739
197 5P3 0.8738
198 27K 0.8737
199 4MX 0.8737
200 KMY 0.8737
201 TB8 0.8735
202 1BW 0.8733
203 64F 0.8731
204 ETV 0.8730
205 GVI 0.8730
206 ZSP 0.8728
207 4AB 0.8721
208 12R 0.8717
209 4B0 0.8714
210 AMR 0.8713
211 HL6 0.8713
212 9GP 0.8709
213 CX4 0.8708
214 1X8 0.8708
215 TL5 0.8705
216 UN4 0.8705
217 TLG 0.8703
218 QIF 0.8702
219 EMU 0.8701
220 ASE 0.8698
221 IKY 0.8698
222 3RI 0.8696
223 NHT 0.8695
224 JPS 0.8695
225 5WN 0.8694
226 GXD 0.8692
227 LNR 0.8690
228 NEU 0.8687
229 AH9 0.8686
230 TXW 0.8681
231 A4V 0.8680
232 A7K 0.8678
233 NKI 0.8672
234 JXQ 0.8668
235 CXH 0.8668
236 1BD 0.8665
237 M78 0.8663
238 QH3 0.8660
239 HWH 0.8660
240 8GK 0.8656
241 8YH 0.8655
242 1Q4 0.8655
243 B0K 0.8649
244 GA2 0.8648
245 JD7 0.8647
246 9E3 0.8645
247 E7S 0.8644
248 SJK 0.8643
249 BB4 0.8641
250 EOL 0.8641
251 JXK 0.8635
252 OX2 0.8627
253 HL4 0.8624
254 TOH 0.8622
255 BC3 0.8614
256 BQ2 0.8612
257 3TC 0.8609
258 AOY 0.8608
259 6VD 0.8608
260 4GP 0.8602
261 CDY 0.8599
262 7AP 0.8599
263 22T 0.8595
264 2JX 0.8594
265 KG1 0.8588
266 3WK 0.8587
267 1KN 0.8580
268 FC2 0.8580
269 A6Z 0.8574
270 UN9 0.8571
271 52F 0.8558
272 H33 0.8558
273 STV 0.8555
274 AS3 0.8554
275 PE2 0.8550
276 5ER 0.8544
277 CTE 0.8537
278 AAN 0.8536
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3GE7; Ligand: AFQ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 3ge7.bio1) has 34 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 3GE7; Ligand: AFQ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 3ge7.bio1) has 34 residues
No: Leader PDB Ligand Sequence Similarity
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