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Receptor
PDB id Resolution Class Description Source Keywords
2YY8 2.48 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF ARCHAEAL TRNA-METHYLASE FOR POSITION 56 (ATRM56) FROM PYROCOCCUS HORIKOSHII, COMPLEXED WITH S- A DENOSYL-L-METHIONINE PYROCOCCUS HORIKOSHII DEEP TREFOIL KNOT STRUCTURAL GENOMICS NPPSFA NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE RSGI TRANSFERASE
Ref.: CRYSTAL STRUCTURE AND MUTATIONAL STUDY OF A UNIQUE SPOU FAMILY ARCHAEAL METHYLASE THAT FORMS 2'-O-METHYLCYTIDINE AT POSITION 56 OF TRNA J.MOL.BIOL. V. 375 1064 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MTA A:400;
Valid;
none;
submit data
297.334 C11 H15 N5 O3 S CSC[C...
SAM B:500;
Valid;
none;
submit data
398.437 C15 H22 N6 O5 S C[S@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2YY8 2.48 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF ARCHAEAL TRNA-METHYLASE FOR POSITION 56 (ATRM56) FROM PYROCOCCUS HORIKOSHII, COMPLEXED WITH S- A DENOSYL-L-METHIONINE PYROCOCCUS HORIKOSHII DEEP TREFOIL KNOT STRUCTURAL GENOMICS NPPSFA NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE RSGI TRANSFERASE
Ref.: CRYSTAL STRUCTURE AND MUTATIONAL STUDY OF A UNIQUE SPOU FAMILY ARCHAEAL METHYLASE THAT FORMS 2'-O-METHYLCYTIDINE AT POSITION 56 OF TRNA J.MOL.BIOL. V. 375 1064 2008
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 2YY8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 2YY8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 2YY8 - SAM C15 H22 N6 O5 S C[S@@+](CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: MTA; Similar ligands found: 267
No: Ligand ECFP6 Tc MDL keys Tc
1 MTA 1 1
2 DTA 0.786885 0.867647
3 3DH 0.777778 0.938462
4 ADN 0.758621 0.878788
5 RAB 0.758621 0.878788
6 XYA 0.758621 0.878788
7 DSH 0.705882 0.84507
8 5N5 0.704918 0.878788
9 A4D 0.693548 0.907692
10 5CD 0.693548 0.892308
11 EP4 0.6875 0.939394
12 M2T 0.676923 0.940298
13 A7D 0.657534 0.882353
14 5X8 0.64 0.895522
15 5AD 0.639344 0.857143
16 AMP 0.628571 0.794521
17 A 0.628571 0.794521
18 ZAS 0.628571 0.816901
19 LMS 0.628571 0.719512
20 A5D 0.623377 0.867647
21 SAH 0.615385 0.869565
22 ABM 0.60274 0.821918
23 J7C 0.60274 0.794521
24 AAT 0.6 0.797297
25 6RE 0.597222 0.783784
26 SRA 0.597222 0.776316
27 S4M 0.594595 0.84
28 AOC 0.589041 0.880597
29 MAO 0.586667 0.805195
30 S8M 0.583333 0.833333
31 A2D 0.581081 0.773333
32 A3N 0.581081 0.867647
33 5AS 0.578947 0.697674
34 GJV 0.573333 0.773333
35 A12 0.565789 0.74359
36 AP2 0.565789 0.74359
37 BA3 0.565789 0.773333
38 AU1 0.564103 0.753247
39 ADX 0.564103 0.719512
40 M33 0.564103 0.810811
41 MHZ 0.564103 0.805195
42 B4P 0.558442 0.773333
43 AP5 0.558442 0.773333
44 ADP 0.558442 0.773333
45 7D7 0.553846 0.794118
46 Y3J 0.552239 0.80303
47 AN2 0.551282 0.763158
48 AT4 0.551282 0.766234
49 SON 0.551282 0.74359
50 SXZ 0.550562 0.849315
51 PRX 0.55 0.8
52 A6D 0.545455 0.766234
53 CA0 0.544304 0.753247
54 AD9 0.54321 0.753247
55 SA8 0.54321 0.873239
56 EEM 0.542169 0.849315
57 ACP 0.5375 0.753247
58 SFG 0.5375 0.826087
59 50T 0.5375 0.763158
60 HEJ 0.5375 0.773333
61 ATP 0.5375 0.773333
62 5FA 0.530864 0.773333
63 AQP 0.530864 0.773333
64 APC 0.530864 0.74359
65 APR 0.530864 0.773333
66 AR6 0.530864 0.773333
67 ANP 0.53012 0.753247
68 SAM 0.53012 0.875
69 SMM 0.529412 0.84
70 3AM 0.527027 0.756757
71 NEC 0.526316 0.823529
72 RBY 0.52439 0.74359
73 AGS 0.52439 0.75641
74 SAP 0.52439 0.75641
75 ADP PO3 0.52439 0.794521
76 ADV 0.52439 0.74359
77 5AL 0.52381 0.786667
78 54H 0.523256 0.705882
79 VMS 0.523256 0.705882
80 3AD 0.521739 0.863636
81 MTH 0.520548 0.984127
82 G5A 0.518072 0.678161
83 SAI 0.518072 0.830986
84 A5A 0.517647 0.722892
85 ME8 0.516484 0.797468
86 GAP 0.511905 0.753247
87 ACQ 0.511905 0.753247
88 T99 0.511905 0.766234
89 TAT 0.511905 0.766234
90 S7M 0.511628 0.824324
91 8QN 0.511364 0.786667
92 9ZD 0.511364 0.769231
93 9ZA 0.511364 0.769231
94 CC5 0.507463 0.876923
95 A3G 0.506494 0.828571
96 A3P 0.506329 0.77027
97 52H 0.505747 0.697674
98 NVA LMS 0.5 0.693182
99 7D5 0.5 0.714286
100 8X1 0.5 0.655556
101 53H 0.5 0.697674
102 ALF ADP 0.5 0.734177
103 ATF 0.5 0.74359
104 TSB 0.5 0.714286
105 MTP 0.5 0.828571
106 MAP 0.5 0.734177
107 ADP ALF 0.5 0.734177
108 DAL AMP 0.5 0.786667
109 25A 0.494382 0.773333
110 5SV 0.494382 0.759494
111 VO4 ADP 0.494253 0.763158
112 6YZ 0.494253 0.753247
113 ADP VO4 0.494253 0.763158
114 SRP 0.494253 0.74359
115 SSA 0.494253 0.678161
116 2AM 0.493333 0.746667
117 26A 0.492958 0.867647
118 PAJ 0.488889 0.75
119 LSS 0.488889 0.701149
120 A1R 0.488889 0.725
121 DSZ 0.488889 0.678161
122 ADQ 0.488889 0.753247
123 0UM 0.488889 0.810811
124 A3R 0.488889 0.725
125 3OD 0.483871 0.776316
126 AHX 0.483516 0.716049
127 62X 0.483516 0.815789
128 5CA 0.483146 0.678161
129 A22 0.483146 0.763158
130 A3T 0.481928 0.880597
131 2VA 0.481928 0.855072
132 RP1 0.480519 0.75
133 SP1 0.480519 0.75
134 3L1 0.478873 0.8
135 3D1 0.478873 0.8
136 OAD 0.478261 0.776316
137 LEU LMS 0.478261 0.693182
138 9X8 0.478261 0.779221
139 K15 0.478261 0.813333
140 OOB 0.477778 0.763158
141 GEK 0.477778 0.833333
142 A3S 0.47561 0.84058
143 OVE 0.474359 0.74026
144 P5A 0.473118 0.648352
145 PR8 0.473118 0.698795
146 NSS 0.472527 0.678161
147 4AD 0.472527 0.734177
148 AMO 0.472527 0.74359
149 2FA 0.472222 0.816901
150 6MD 0.472222 0.893939
151 NOC 0.471429 0.791045
152 NVA 2AD 0.470588 0.833333
153 A2P 0.469136 0.756757
154 2BA 0.469136 0.767123
155 CMP 0.469136 0.777778
156 9K8 0.468085 0.674157
157 PTJ 0.468085 0.759494
158 TXA 0.468085 0.766234
159 1ZZ 0.468085 0.731707
160 QQX 0.467532 0.714286
161 DLL 0.467391 0.763158
162 00A 0.467391 0.725
163 5F1 0.465753 0.782609
164 MYR AMP 0.463158 0.731707
165 3UK 0.462366 0.753247
166 ADP BMA 0.462366 0.753247
167 QQY 0.461538 0.723684
168 ACK 0.461538 0.739726
169 WAQ 0.457447 0.725
170 LAD 0.457447 0.707317
171 A A 0.457447 0.773333
172 B5V 0.457447 0.74359
173 GSU 0.457447 0.678161
174 KAA 0.457447 0.655556
175 PPS 0.454545 0.698795
176 B5Y 0.453608 0.75641
177 B5M 0.453608 0.75641
178 PAP 0.453488 0.76
179 BIS 0.452632 0.725
180 JB6 0.452632 0.746835
181 NB8 0.452632 0.716049
182 FYA 0.452632 0.763158
183 1DA 0.452055 0.878788
184 XAH 0.44898 0.690476
185 SO8 0.448276 0.869565
186 VRT 0.448276 0.84507
187 25L 0.447917 0.763158
188 KB1 0.447917 0.786667
189 4UV 0.444444 0.734177
190 9SN 0.443299 0.716049
191 V3L 0.443182 0.773333
192 LAQ 0.441176 0.710843
193 7D3 0.439024 0.696203
194 FA5 0.438776 0.74359
195 YAP 0.438776 0.734177
196 ATP A A A 0.438776 0.783784
197 8PZ 0.438776 0.678161
198 J1A 0.4375 0.740741
199 LPA AMP 0.436893 0.710843
200 J1C 0.435897 0.67033
201 7MD 0.435644 0.690476
202 AFH 0.435644 0.707317
203 GA7 0.435644 0.789474
204 4UU 0.435644 0.734177
205 J1B 0.434783 0.67033
206 YSA 0.434343 0.678161
207 4UW 0.432692 0.75
208 TXD 0.432692 0.746835
209 ARJ 0.432432 0.776119
210 MCF 0.432099 0.842857
211 GTA 0.431373 0.731707
212 TAD 0.431373 0.728395
213 KH3 0.431373 0.802632
214 4YB 0.431373 0.662921
215 TYR AMP 0.43 0.734177
216 AMP DBH 0.43 0.753247
217 IVH 0.428571 0.813333
218 AHZ 0.427184 0.731707
219 3NZ 0.427083 0.833333
220 7C5 0.425743 0.773333
221 G3A 0.425743 0.716049
222 2A5 0.425287 0.708861
223 7MC 0.424528 0.694118
224 AP0 0.424528 0.7375
225 TT8 0.423913 0.898551
226 YLP 0.423077 0.694118
227 48N 0.423077 0.7375
228 CNA 0.422018 0.74359
229 ARG AMP 0.421569 0.682353
230 AR6 AR6 0.421569 0.773333
231 G5P 0.421569 0.716049
232 ATR 0.420455 0.746667
233 101 0.419753 0.714286
234 D3Y 0.419355 0.816901
235 NXX 0.419048 0.74359
236 DND 0.419048 0.74359
237 6V0 0.419048 0.716049
238 NAX 0.419048 0.698795
239 NAI 0.419048 0.725
240 7D4 0.418605 0.696203
241 DQV 0.417476 0.763158
242 A A A 0.416667 0.763158
243 OMR 0.415094 0.722892
244 TXE 0.415094 0.725
245 649 0.415094 0.648352
246 D5M 0.414634 0.714286
247 DA 0.414634 0.714286
248 139 0.412844 0.698795
249 T5A 0.412844 0.694118
250 ADJ 0.412844 0.702381
251 YLB 0.411215 0.714286
252 YLC 0.411215 0.710843
253 F0P 0.411215 0.797297
254 8Q2 0.411215 0.655556
255 J1D 0.410714 0.628866
256 AYB 0.409091 0.705882
257 A2R 0.408602 0.763158
258 A4P 0.407407 0.659091
259 UP5 0.40566 0.734177
260 F2R 0.405405 0.674419
261 IOT 0.40367 0.666667
262 6CR 0.402597 0.805556
263 WSA 0.401869 0.686047
264 TYM 0.401869 0.74359
265 AF3 ADP 3PG 0.401869 0.707317
266 4TA 0.401786 0.702381
267 YLA 0.4 0.674419
Ligand no: 2; Ligand: SAM; Similar ligands found: 202
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 ADN 0.565789 0.773333
9 RAB 0.565789 0.773333
10 XYA 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 5AL 0.510417 0.743902
25 54H 0.510204 0.673913
26 VMS 0.510204 0.673913
27 0UM 0.51 0.857143
28 AMP 0.505747 0.707317
29 LMS 0.505747 0.666667
30 A 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 SON 0.5 0.746988
34 SSA 0.5 0.684783
35 6RE 0.5 0.78481
36 K15 0.5 0.883117
37 5AD 0.5 0.75
38 SRP 0.5 0.746988
39 LSS 0.49505 0.706522
40 CA0 0.494624 0.714286
41 A12 0.494505 0.705882
42 AP2 0.494505 0.705882
43 ME8 0.490385 0.841463
44 TSB 0.49 0.681319
45 53H 0.49 0.666667
46 DAL AMP 0.49 0.765432
47 5CA 0.49 0.684783
48 ACP 0.489362 0.694118
49 ADP 0.48913 0.690476
50 5AS 0.48913 0.648936
51 J7C 0.488889 0.772152
52 A2D 0.488889 0.690476
53 ZAS 0.488636 0.769231
54 9ZD 0.485149 0.729412
55 9ZA 0.485149 0.729412
56 8QN 0.485149 0.743902
57 GAP 0.484536 0.73494
58 AN2 0.483871 0.682353
59 A3S 0.483871 0.813333
60 A7D 0.483871 0.851351
61 GJV 0.483516 0.775
62 SRA 0.483146 0.694118
63 LAD 0.480769 0.752941
64 KAA 0.480769 0.698925
65 GSU 0.480769 0.722222
66 AMO 0.480392 0.746988
67 DSZ 0.480392 0.703297
68 52H 0.48 0.666667
69 M33 0.478723 0.722892
70 BA3 0.478261 0.690476
71 MAO 0.478261 0.82716
72 NEC 0.477778 0.75
73 AOC 0.477778 0.776316
74 DSH 0.477778 0.842105
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 NVA LMS 0.475728 0.736264
78 Y3J 0.47561 0.706667
79 G5A 0.474227 0.684783
80 A3T 0.473684 0.8
81 B4P 0.473118 0.690476
82 AP5 0.473118 0.690476
83 A3N 0.472527 0.766234
84 KB1 0.471698 0.833333
85 PRX 0.46875 0.73494
86 APC 0.46875 0.705882
87 AT4 0.468085 0.686047
88 PAJ 0.466019 0.712644
89 4AD 0.466019 0.759036
90 RBY 0.463918 0.72619
91 ADP PO3 0.463918 0.728395
92 ADV 0.463918 0.72619
93 ADX 0.463158 0.666667
94 MHZ 0.463158 0.82716
95 AU1 0.463158 0.674419
96 YAP 0.462963 0.738095
97 TXA 0.462264 0.72619
98 NB8 0.462264 0.72093
99 A3G 0.461538 0.802632
100 VRT 0.459184 0.842105
101 XAH 0.458716 0.715909
102 YSA 0.458716 0.684783
103 HEJ 0.458333 0.690476
104 50T 0.458333 0.682353
105 ATP 0.458333 0.690476
106 LEU LMS 0.457143 0.717391
107 7D7 0.45679 0.723684
108 KH3 0.455357 0.871795
109 ACQ 0.454545 0.694118
110 AR6 0.453608 0.710843
111 APR 0.453608 0.710843
112 AQP 0.453608 0.690476
113 5FA 0.453608 0.690476
114 NSS 0.451923 0.703297
115 FA5 0.449541 0.746988
116 A5D 0.44898 0.789474
117 AD9 0.44898 0.674419
118 AGS 0.44898 0.678161
119 SAP 0.44898 0.678161
120 PTJ 0.448598 0.72093
121 YLB 0.448276 0.758621
122 YLP 0.447368 0.738636
123 8X1 0.446602 0.680851
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 3AM 0.444444 0.674699
128 MYR AMP 0.444444 0.776471
129 OAD 0.443396 0.73494
130 2VA 0.443299 0.779221
131 S8M 0.442308 0.831169
132 OOB 0.442308 0.722892
133 TYR AMP 0.441441 0.759036
134 6YZ 0.441176 0.694118
135 ADP VO4 0.441176 0.702381
136 VO4 ADP 0.441176 0.702381
137 T99 0.44 0.686047
138 TAT 0.44 0.686047
139 ANP 0.44 0.674419
140 WAQ 0.439252 0.75
141 B5Y 0.436364 0.717647
142 8PZ 0.436364 0.684783
143 F0P 0.435897 0.844156
144 YLC 0.435897 0.755814
145 AAT 0.435644 0.797468
146 1ZZ 0.435185 0.755814
147 9K8 0.435185 0.663158
148 3OD 0.435185 0.73494
149 NVA 2AD 0.434343 0.855263
150 00A 0.433962 0.689655
151 DLL 0.433962 0.722892
152 ARG AMP 0.433628 0.727273
153 7MD 0.433628 0.715909
154 ATF 0.431373 0.666667
155 SO8 0.43 0.792208
156 3UK 0.429907 0.714286
157 A6D 0.429907 0.72619
158 9X8 0.429907 0.717647
159 F2R 0.429752 0.7
160 5SV 0.428571 0.741176
161 AMP DBH 0.428571 0.714286
162 TYM 0.42735 0.746988
163 WSA 0.42735 0.692308
164 9SN 0.427273 0.681818
165 AHZ 0.426087 0.755814
166 P5A 0.425926 0.691489
167 B5V 0.425926 0.705882
168 PR8 0.425926 0.744186
169 A A 0.425926 0.710843
170 3NZ 0.425926 0.807692
171 A1R 0.424528 0.709302
172 2A5 0.424242 0.674419
173 7MC 0.423729 0.719101
174 B5M 0.423423 0.717647
175 7D5 0.422222 0.658824
176 JB6 0.422018 0.709302
177 FYA 0.422018 0.722892
178 AYB 0.421488 0.75
179 A22 0.419048 0.682353
180 MAP 0.419048 0.659091
181 2AM 0.417582 0.666667
182 TAD 0.417391 0.712644
183 A3P 0.416667 0.686747
184 ADP BMA 0.416667 0.714286
185 25A 0.415094 0.690476
186 YLA 0.413223 0.719101
187 8Q2 0.411765 0.663158
188 A3R 0.411215 0.709302
189 ADQ 0.411215 0.694118
190 48N 0.410256 0.72093
191 0XU 0.41 0.824324
192 GA7 0.408696 0.72619
193 7D3 0.40625 0.643678
194 PAP 0.405941 0.678571
195 DQV 0.405172 0.702381
196 OVE 0.404255 0.662791
197 4UV 0.403509 0.697674
198 AF3 ADP 3PG 0.403361 0.712644
199 3AD 0.402299 0.783784
200 CMP 0.402062 0.691358
201 2BA 0.402062 0.682927
202 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2YY8; Ligand: MTA; Similar sites found with APoc: 178
This union binding pocket(no: 1) in the query (biounit: 2yy8.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 2UZI GTP None
2 2C5L GTP None
3 6FA4 GNP None
4 1XUJ BOZ 0.995025
5 5TP0 BRN 0.995025
6 3NK7 SAM 1.49254
7 2WSI FAD 1.49254
8 1OSS BEN 1.99005
9 6GAR FAD 1.99005
10 1YXM ADE 1.99005
11 1YKJ FAD 1.99005
12 1VJY 460 2.48756
13 1QL9 ZEN 2.69058
14 3KIF GDL 2.83019
15 3AB1 FAD 2.98507
16 3LZW FAD 2.98507
17 1ZK7 FAD 2.98507
18 1PQ7 ARG 2.98507
19 2RGJ FAD 2.98507
20 4HA6 FAD 3.14961
21 1GJC 130 3.48259
22 1V6A TRE 3.48259
23 4CNK FAD 3.48259
24 1I8T FAD 3.48259
25 5L4S NAP 3.48259
26 5L4S 6KX 3.48259
27 6H3O FAD 3.48259
28 1AE1 NAP 3.48259
29 6FK3 PPI 3.54478
30 1E96 GTP 3.64583
31 1N07 ADP 3.68098
32 5OCG GNP 3.7037
33 1MXI SAH 3.75
34 4JWF SAH 3.9801
35 2Q7V FAD 3.9801
36 5FJN FAD 3.9801
37 5FJN BE2 3.9801
38 3MKH FAD 3.9801
39 3GF4 FAD 3.9801
40 4GKV NAD 3.9801
41 2XTZ GSP 3.9801
42 2NU8 COA 4.47761
43 4JWH SAH 4.47761
44 2X2M X2M 4.47761
45 1K97 CIR 4.47761
46 1K97 ASP 4.47761
47 3K7M FAD 4.47761
48 3ICT FAD 4.47761
49 3ICS FAD 4.47761
50 2OQ2 A3P 4.47761
51 3ICR FAD 4.47761
52 4JAL SAH 4.79042
53 5WB6 9ZM 4.91803
54 5Q0F 9FA 4.91803
55 1GPM AMP 4.97512
56 4Y93 746 4.97512
57 2WET FAD 4.97512
58 2QRK AMP 4.97512
59 3BBH SFG 5.47264
60 4CNE SAH 5.47264
61 3BBD SAH 5.47264
62 1EB1 ZAL PRO MMO 5.47264
63 4AX9 N5N 5.47264
64 1A2C 34H LEU PRJ OAR 5.47264
65 1EFV FAD 5.47264
66 4O97 NTX 5.47264
67 1EFV AMP 5.47264
68 5CEO 50D 5.47264
69 1SL3 170 5.47264
70 2E5V FAD 5.47264
71 5GUD NDP 5.47264
72 5LMK 6ZK 5.47264
73 4K81 GTP 5.47264
74 1T90 NAD 5.47264
75 3RK1 ATP 5.47264
76 1D9I 00P 5.47264
77 6GAS FAD 5.47264
78 4E93 GUI 5.47264
79 3DDC GNP 5.52147
80 3O7B SAH 5.7377
81 1OIX GDP 5.75916
82 1P9P SAH 5.97015
83 4MCC 21X 5.97015
84 1JGT CMA 5.97015
85 1JGT APC 5.97015
86 5L2Z 70C 5.97015
87 1KNR FAD 5.97015
88 1GPE FAD 5.97015
89 5UIU 8CG 5.97015
90 1I1N SAH 5.97015
91 2EC9 24X 5.97015
92 6EMU SAM 6.09137
93 2H29 DND 6.34921
94 2P3T 993 6.46766
95 5H5F SAM 6.96517
96 4BTI 7R9 6.96517
97 5O2T GSP 6.96517
98 2VH6 GSV 6.96517
99 1UTJ ABN 6.96517
100 3AXB FAD 6.96517
101 3AXB PRO 6.96517
102 4J7U NAP 6.96517
103 4J7U YTZ 6.96517
104 4XJ7 ADE 6.96517
105 5A7Y SAH 7.46269
106 3FC2 IBI 7.46269
107 3AB4 THR 7.46269
108 4NBU NAI 7.46269
109 5I39 FAD 7.46269
110 6F97 FAD 7.46269
111 1GTE FAD 7.9602
112 5TTJ FAD 7.9602
113 6GNO XDI 8.14815
114 1NFU RRP 8.20513
115 4EWH T77 8.45771
116 2BNE U5P 8.45771
117 3CGB FAD 8.45771
118 5O96 SAM 8.95522
119 3G6K FAD 8.95522
120 3G6K POP 8.95522
121 1HSR BHO 8.95522
122 1O94 AMP 8.95522
123 5J60 FAD 8.95522
124 1O97 AMP 8.95522
125 1O97 FAD 8.95522
126 5N5S NAP 8.95522
127 5W4W 9WG 8.95522
128 4RRG A3T 9.21986
129 1NVV GNP 9.45274
130 6D5M GNP 9.45274
131 6D5H GNP 9.45274
132 6D55 GNP 9.45274
133 6D5V GNP 9.45274
134 6D5G GNP 9.45274
135 6D5L GNP 9.45274
136 6BVI GNP 9.45274
137 6D5J GNP 9.45274
138 6BVK GNP 9.45274
139 6D5E GNP 9.45274
140 6D59 GNP 9.45274
141 6D56 GNP 9.45274
142 2XA2 UPG 9.45274
143 6BVM GNP 9.45274
144 1Q19 APC 9.45274
145 2QTR NXX 9.52381
146 1GUA GNP 9.58084
147 4CNG SAH 9.95025
148 4JWJ SAH 9.95025
149 4FK7 P34 9.95025
150 1U7T TDT 9.95025
151 1YP4 ADP 9.95025
152 5ODQ FAD 10.3679
153 1NAA 6FA 10.4478
154 1NAA ABL 10.4478
155 5MBX SP5 10.4478
156 5MBX FAD 10.4478
157 1C0I FAD 10.4478
158 1C0I BE2 10.4478
159 3A06 NDP 10.9453
160 5WS9 AMP 11.9403
161 5TWJ SAM 12.3457
162 1MJH ATP 12.3457
163 1A0J BEN 12.4378
164 4NBI D3Y 12.8049
165 3N7O N7O 12.9353
166 5JCA FAD 13.3803
167 1V2X SAM 13.9175
168 3TWO NDP 14.4279
169 3GYQ SAM 14.9254
170 5EYK 5U5 15.2542
171 1CT9 AMP 15.4229
172 5ZYN FAD 15.4229
173 1KOR ARG 16.4179
174 1KOR SIN 16.4179
175 1KOR ANP 16.4179
176 1RYD GLC 16.9154
177 2VN9 GVD 18.9055
178 4HDO GNP 23.8806
Pocket No.: 2; Query (leader) PDB : 2YY8; Ligand: SAM; Similar sites found with APoc: 103
This union binding pocket(no: 2) in the query (biounit: 2yy8.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 2BOS GLA GAL GLC None
2 2BOS GLA GAL GLC NBU None
3 6FX2 FUC C4W NAG BMA MAN NAG GAL None
4 5TP0 BRN 0.995025
5 3NK7 SAM 1.49254
6 2WSI FAD 1.49254
7 1O6B ADP 1.77515
8 1YXM ADE 1.99005
9 1OSS BEN 1.99005
10 4C2C ALA ALA ALA 1.99005
11 2NW9 FT6 2.48756
12 1GJC 130 3.48259
13 1XF1 CIT 3.48259
14 3HQP FDP 3.48259
15 5BVA FAD 3.48259
16 1V6A TRE 3.48259
17 6H3O FAD 3.48259
18 1MXI SAH 3.75
19 4JWF SAH 3.9801
20 4JWH SAH 4.47761
21 2NU8 COA 4.47761
22 3ITJ FAD 4.47761
23 3W6X HZP 4.47761
24 2OQ2 A3P 4.47761
25 1KGZ PRP 4.47761
26 5TWB FAD 4.47761
27 4JAL SAH 4.79042
28 5WB6 9ZM 4.91803
29 5Q0F 9FA 4.91803
30 1NXJ GLV 4.91803
31 1GPM AMP 4.97512
32 2WET FAD 4.97512
33 6F5W KG1 4.97512
34 3BBH SFG 5.47264
35 3BBD SAH 5.47264
36 4CNE SAH 5.47264
37 3RK1 ATP 5.47264
38 1L7N ALF 5.47264
39 1EB1 ZAL PRO MMO 5.47264
40 1A2C 34H LEU PRJ OAR 5.47264
41 3HMO STU 5.47264
42 4O97 NTX 5.47264
43 1EFV AMP 5.47264
44 1EFV FAD 5.47264
45 2BPM 529 5.47264
46 4MIG G3F 5.47264
47 3O7B SAH 5.7377
48 1P9P SAH 5.97015
49 4MCC 21X 5.97015
50 5KGS 6SR 5.97015
51 1JGT CMA 5.97015
52 1JGT APC 5.97015
53 4UP3 FAD 5.97015
54 1GPE FAD 5.97015
55 6EMU SAM 6.09137
56 1O5E 132 6.14035
57 1ZHS NAG NAG BMA MAN MAN 6.19469
58 1MRH FMC 6.46766
59 4RR7 A3S 6.46766
60 3PD2 A3S 6.80272
61 5H5F SAM 6.96517
62 4KCT FDP 6.96517
63 2JLD AG1 6.96517
64 3ZRM ZRM 6.96517
65 2OQ5 BEN 6.96517
66 4I6H 1C8 6.96517
67 3DXY SAM 6.96517
68 5A7Y SAH 7.46269
69 3AB4 THR 7.46269
70 1GTE FAD 7.9602
71 6GNO XDI 8.14815
72 1NFU RRP 8.20513
73 2XYA 7L4 8.79121
74 5O96 SAM 8.95522
75 3G6K POP 8.95522
76 3G6K FAD 8.95522
77 5J60 FAD 8.95522
78 4RRG A3T 9.21986
79 4CNG SAH 9.95025
80 4JWJ SAH 9.95025
81 3B2Q AES 9.95025
82 4FK7 P34 9.95025
83 3VSV XYS 10.4478
84 1NAA 6FA 10.4478
85 1NAA ABL 10.4478
86 1WLJ U5P 11.9403
87 5WS9 AMP 11.9403
88 1V59 NAD 12.1339
89 5TWJ SAM 12.3457
90 1A0J BEN 12.4378
91 2ZFZ ARG 12.6582
92 4NBI D3Y 12.8049
93 1V2X SAM 13.9175
94 3GYQ SAM 14.9254
95 1CT9 AMP 15.4229
96 5X2N ALA 15.4229
97 3PTG 932 15.9204
98 5G3L SIA 16.1616
99 1COY FAD 17.4129
100 1LOJ URI 22.9885
101 5TVA AMP 24.8756
102 2PKA BEN 26.25
103 1G51 AMP 26.3682
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