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Receptor
PDB id Resolution Class Description Source Keywords
2XZ9 1.68 Å EC: 2.7.3.9 CRYSTAL STRUCTURE FROM THE PHOSPHOENOLPYRUVATE-BINDING DOMAI ENZYME I IN COMPLEX WITH PYRUVATE FROM THE THERMOANAEROBACTT ENGCONGENSIS PEP-SUGAR PHOSPHOTRANSFERASE SYSTEM (PTS) THERMOANAEROBACTER TENGCONGENSIS THERMOPHILIC PEP-UTILISING ENZYME TRANSFERASE
Ref.: PHOSPHOENOLPYRUVATE: SUGAR PHOSPHOTRANSFERASE SYSTE THE HYPERTHERMOPHILIC THERMOANAEROBACTER TENGCONGEN BIOCHEMISTRY V. 50 1184 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG A:1;
B:1;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
PYR A:6450;
B:6450;
Valid;
Valid;
none;
none;
submit data
88.062 C3 H4 O3 CC(=O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2XZ9 1.68 Å EC: 2.7.3.9 CRYSTAL STRUCTURE FROM THE PHOSPHOENOLPYRUVATE-BINDING DOMAI ENZYME I IN COMPLEX WITH PYRUVATE FROM THE THERMOANAEROBACTT ENGCONGENSIS PEP-SUGAR PHOSPHOTRANSFERASE SYSTEM (PTS) THERMOANAEROBACTER TENGCONGENSIS THERMOPHILIC PEP-UTILISING ENZYME TRANSFERASE
Ref.: PHOSPHOENOLPYRUVATE: SUGAR PHOSPHOTRANSFERASE SYSTE THE HYPERTHERMOPHILIC THERMOANAEROBACTER TENGCONGEN BIOCHEMISTRY V. 50 1184 2011
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2XZ9 - PYR C3 H4 O3 CC(=O)C(=O....
2 2XZ7 - PEP C3 H5 O6 P C=C(C(=O)O....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2XZ9 - PYR C3 H4 O3 CC(=O)C(=O....
2 2XZ7 - PEP C3 H5 O6 P C=C(C(=O)O....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2XZ9 - PYR C3 H4 O3 CC(=O)C(=O....
2 2XZ7 - PEP C3 H5 O6 P C=C(C(=O)O....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: PYR; Similar ligands found: 7
No: Ligand ECFP6 Tc MDL keys Tc
1 PYR 1 1
2 ACY 0.636364 0.636364
3 OXD 0.545455 0.642857
4 F50 0.428571 0.6
5 2KT 0.411765 0.733333
6 AAE 0.411765 0.625
7 KIV 0.411765 0.785714
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2XZ9; Ligand: PYR; Similar sites found with APoc: 592
This union binding pocket(no: 1) in the query (biounit: 2xz9.bio1) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 5O3Q CMP None
2 1ZUI SKM None
3 4GJ3 0XP 0.993378
4 2QG6 NMN 1.00503
5 3TXO 07U 1.23457
6 5WRI A3P 1.25
7 1JE1 GMP 1.27119
8 3KYG 5GP 5GP 1.32159
9 4UTG ANP 1.54321
10 2QZS 250 1.54321
11 2QZS GLC 1.54321
12 2QZS ADP 1.54321
13 5H81 NAP 1.54321
14 3D91 REM 1.54321
15 4OH4 ANP 1.54321
16 6BMS PLM 1.54321
17 5UR0 NAD 1.54321
18 1T26 GBD 1.5528
19 1T26 NAI 1.5528
20 5AAV GW5 1.5873
21 3DKP ADP 1.63265
22 3RT4 LP5 1.75439
23 5CXX FER 1.81818
24 3DZD ADP 1.85185
25 4MO2 FAD 1.85185
26 4MO2 FDA 1.85185
27 1NHX FTB 1.85185
28 1NHX PEP 1.85185
29 2GMV UN8 1.85185
30 4LOO SB4 1.85185
31 5GSN FAD 1.85185
32 5GSN NAP 1.85185
33 4PFO ADP 1.85185
34 4MOP 2H5 1.85185
35 1H65 GDP 1.85185
36 6FYZ EBE 1.85185
37 4LED XXR 1.86567
38 2FUE M1P 1.9084
39 1SQ5 ADP 1.94805
40 5EJ2 NAD 1.94805
41 2GWH A3P 2.01342
42 5F5N NAD 2.07612
43 5Y2W PGA 2.13675
44 2PID YSA 2.16049
45 3TKY SAH 2.16049
46 4PLG OXM 2.16049
47 4PLG NAI 2.16049
48 2XVF FAD 2.16049
49 4BVA T3 2.16049
50 4BVA NDP 2.16049
51 4P53 NAI 2.16049
52 4AP3 NAP 2.16049
53 4AP3 FAD 2.16049
54 1GQY ACP 2.16049
55 1Q0H FOM 2.16049
56 1Q0H NDP 2.16049
57 1BW9 PPY 2.16049
58 1RRM APR 2.16049
59 3LXK MI1 2.16049
60 5NUF NAD 2.16049
61 4XGU ADP 2.16049
62 3CIF NAD 2.16049
63 5EOB 5QQ 2.19436
64 3LXN MI1 2.20126
65 1CX4 CMP 2.29508
66 1ZY5 ANP 2.31023
67 3TMK T5A 2.31481
68 5OX6 A1Z 2.38095
69 1IIM TTP 2.39726
70 3IP8 B85 2.41935
71 3W8X FTK 2.46914
72 3W8X FAD 2.46914
73 4U8P UDP 2.46914
74 4U8P FDA 2.46914
75 4PFW MAN MAN BMA BMA BMA BMA 2.46914
76 5I34 GDP 2.46914
77 1OXV ANP 2.46914
78 2NP9 YE1 2.46914
79 5XDR ADP 2.46914
80 1SOW NAD 2.46914
81 4LIK CIT 2.46914
82 4ZCC NAI 2.46914
83 4ZCC FAD 2.46914
84 2BO4 FLC 2.46914
85 4DCT GDP 2.46914
86 2MBR EPU 2.46914
87 2MBR FAD 2.46914
88 5MY8 RXZ 2.46914
89 1XJD STU 2.46914
90 1HDG NAD 2.46914
91 1F5N GNP 2.46914
92 4J75 TYM 2.46914
93 1SVK ALF GDP 2.46914
94 2OM2 GDP 2.46914
95 6CBO DOW 2.46914
96 1DL5 SAH 2.52366
97 2PTM CMP 2.52525
98 5EYK 5U5 2.53623
99 3C3N FMN 2.5641
100 3PQC GDP 2.5641
101 4L3L 5FI 2.63158
102 1W7J ADP BEF 2.64901
103 5EXT ADP 2.69231
104 4J4H NAI 2.7027
105 4JK3 NAD 2.7027
106 1ZP9 ATP 2.71318
107 3HGM ATP 2.72109
108 3WV8 ATP 2.75229
109 1C9K 5GP 2.77778
110 2D4V NAD 2.77778
111 4W93 3L9 2.77778
112 4FRZ ADP 2.77778
113 3C0G 3AM 2.77778
114 4PLT OXM 2.77778
115 4FL3 ANP 2.77778
116 3BAZ NAP 2.77778
117 4LYA ATP 2.77778
118 1BG2 ADP 2.77778
119 2GSD NAD 2.77778
120 3MJY IJZ 2.77778
121 3MJY FMN 2.77778
122 3QJ4 FAD 2.77778
123 5Z20 NAI 2.77778
124 4YZN 4K5 2.78746
125 3G5D 1N1 2.7972
126 1LDN NAD 2.8481
127 3KH5 ADP 2.85714
128 3SJU NDP 2.86738
129 5X20 NAD 2.88462
130 4EN4 ATP 2.88462
131 4EN4 GT0 2.88462
132 4EN4 GT1 2.88462
133 2BNF UTP 2.90456
134 3RG9 NDP 2.91667
135 1LVG ADP 3.0303
136 3U2U UDP 3.04183
137 3V8S 0HD 3.08642
138 2NCD ADP 3.08642
139 3KRB NAP 3.08642
140 3ZRR PXG 3.08642
141 5KVS NAP 3.08642
142 1ICP FMN 3.08642
143 2HSA FMN 3.08642
144 3LRE ADP 3.08642
145 6APL C5P 3.08642
146 3NEM AMO 3.08642
147 4KQL 1SG 3.08642
148 2ZFI ADP 3.08642
149 2IS6 ADP 3.08642
150 3HZT J60 3.08642
151 5CMK GLU 3.0888
152 2PT9 2MH 3.11526
153 5TIV A3P 3.16206
154 2BR6 HSL 3.1746
155 2WW4 ADP 3.18021
156 3FHI ANP 3.24675
157 1RVV INI 3.24675
158 1NN5 ANP 3.25581
159 1NN5 2DT 3.25581
160 3BZ3 YAM 3.26087
161 4ZNL BEF ADP 3.28467
162 4N9I PCG 3.33333
163 2VWT PYR 3.37079
164 3UIM ANP 3.39506
165 4PJ3 ANP 3.39506
166 2JLD AG1 3.39506
167 5VZ0 ADP 3.39506
168 2Y6Q FAD 3.39506
169 5HSA FAS 3.39506
170 3EYA TDP 3.39506
171 2Y6Q I7T 3.39506
172 2XAU ADP 3.39506
173 6FAA ADP 3.39506
174 4CLI 5P8 3.39506
175 2J3M PRI 3.39506
176 2CJ9 SSA 3.39506
177 4J7H TLO 3.39506
178 5VZ0 2BA 3.39506
179 3ZRM ZRM 3.39506
180 5VGR GDP 3.39506
181 4N70 2HX 3.39506
182 2J3M ATP 3.39506
183 3AB3 GDP 3.39506
184 1ZCB GDP 3.39506
185 1KYZ SAH 3.39506
186 5YSE BGC BGC BGC GLC 3.39506
187 5KSZ GCP 3.39506
188 4QOS ADP 3.39623
189 3A76 SPD 3.40909
190 2AEB ABH 3.41615
191 2R40 EPH 3.42205
192 2EV9 NAP 3.42205
193 2EV9 SKM 3.42205
194 5DUF G7A 3.42205
195 1Z0A GDP 3.44828
196 1ZQ9 SAM 3.50877
197 1VM6 NAD 3.50877
198 3T1O GDP 3.53535
199 3RWP ABQ 3.53698
200 5LVP ATP 3.53698
201 1MXH DHF 3.62319
202 1MXH NAP 3.62319
203 4IZC 1GZ 3.63636
204 5KBF CMP 3.65448
205 4QAC KK3 3.68664
206 2G50 PYR 3.7037
207 4KCT PYR 3.7037
208 3HQP OXL 3.7037
209 1RKX NAD 3.7037
210 5XET ME8 3.7037
211 5U6C 7YS 3.7037
212 3ALN ANP 3.7037
213 1JQN DCO 3.7037
214 4NE2 ADP 3.7037
215 4NE2 SH2 3.7037
216 6APV 3L4 3.7037
217 2D3M COA 3.7037
218 5GXU FAD 3.7037
219 3WQT ANP 3.7037
220 4OUE IPT 3.7037
221 3CV6 NAP 3.71517
222 5VOP C2F 3.71622
223 2ZPT A3P 3.72881
224 3MGB PAP 3.76176
225 2KCE D16 3.78788
226 5IFS ADP 3.79747
227 1L2T ATP 3.82979
228 2WQN ADP 3.87097
229 3KVY URA 3.8835
230 5XVH NAP 3.92157
231 3TDV GDP 3.92157
232 5BV6 35G 3.94737
233 2PVN P63 3.97727
234 2KIN ADP 4
235 3CV2 OXL 4.01235
236 1PZG A3D 4.01235
237 2UUU FAD 4.01235
238 2Y65 ADP 4.01235
239 2UUU PL3 4.01235
240 3S1S SAH 4.01235
241 2X1L ADN 4.01235
242 3UYK 0CX 4.01235
243 3RC3 ANP 4.01235
244 1D6H COA 4.01235
245 3M89 GSP 4.01235
246 4ZG4 VO4 ADP 4.01235
247 1CER NAD 4.01235
248 3GNI ATP 4.01235
249 4HI0 GDP 4.0201
250 1T8U A3P 4.04412
251 1T8U UAP SGN IDS SGN 4.04412
252 4TWP AXI 4.05904
253 3HVJ 705 4.0724
254 6GNC FAD 4.08163
255 5K3W PLP 4.15335
256 1DUB CAA 4.21456
257 1PA9 CSN 4.22535
258 1RP0 AHZ 4.22535
259 4NON GDP 4.23077
260 5BQ5 ADP BEF 4.2328
261 1IZC PYR 4.32099
262 1PIG AGL GLC HMC AGL GLC BGC 4.32099
263 5WC2 ADP 4.32099
264 1E1M NAP 4.32099
265 1E1M FAD 4.32099
266 3Q9T FAY 4.32099
267 1ZGS XMM 4.32099
268 2QV7 ADP 4.32099
269 1NY5 ADP 4.32099
270 1P9B GDP 4.32099
271 4WZ8 3W7 4.32099
272 3IAE D7K 4.32099
273 3EWC MCF 4.32099
274 2WKW W22 4.32099
275 2CE7 ADP 4.32099
276 2RDE C2E 4.38247
277 5G5G FAD 4.40252
278 1LVW TYD 4.40678
279 3JQM GTP 4.4586
280 4GOX A3P 4.47284
281 5XKT GNP 4.5
282 1GUZ NAD 4.51613
283 2R42 FPS 4.55696
284 3JUC PCA 4.57516
285 4L9Z COA 4.62963
286 4L9Z OXL 4.62963
287 6C6O ENG 4.62963
288 3TWO NDP 4.62963
289 2IHU TP9 4.62963
290 1IT7 GUN 4.62963
291 5VHC BEF ADP 4.62963
292 2FNA ADP 4.62963
293 2I6A 5I5 4.62963
294 4FJU NAI 4.62963
295 6FYV 3NG 4.62963
296 2IHT TPP 4.62963
297 1UPA TPP 4.62963
298 5XFV FMN 4.62963
299 1LLU NAD 4.62963
300 1SKQ GDP 4.62963
301 2F6U CIT 4.70085
302 3IID APR 4.73934
303 3QVV A3P 4.74576
304 3QVV 3QV 4.74576
305 3IHZ FK5 4.7619
306 5N87 N66 4.79233
307 3NC9 TR3 4.79233
308 5FBN 5WF 4.79705
309 2W2X GSP 4.86486
310 5JFS 6K0 4.87013
311 4CYD CMP 4.88889
312 1N07 ADP 4.90798
313 1UPF URF 4.91071
314 1Z6T ADP 4.93827
315 3GD4 NAD 4.93827
316 5ZXD ATP 4.93827
317 2B8W ALF 5GP 4.93827
318 5LTJ ADP 4.93827
319 2ZPA ADP 4.93827
320 6F92 MVL 4.93827
321 3KB6 NAD 4.93827
322 5TUK FAD 4.93827
323 3VDB 149 4.93827
324 4P4T GDP 4.93827
325 1WQ1 AF3 4.93827
326 3HMO STU 4.93827
327 5U3F 7TS 4.93827
328 2QZ4 ADP 4.96183
329 1KQN NAD 5.01792
330 1P1C SAH 5.02513
331 6BSX GDP 5.05618
332 1WP4 NDP 5.19031
333 5NMX FAD 5.24691
334 5NMX NAP 5.24691
335 1IWE IMP 5.24691
336 2IO8 ADP 5.24691
337 3HDY GDU 5.24691
338 4Q3S X7A 5.24691
339 3HDY FAD 5.24691
340 2JK0 ASP 5.24691
341 4JB1 FAD 5.29412
342 4JB1 NAP 5.29412
343 2WJH FLC 5.42169
344 2WJH GDP 5.42169
345 6G14 G4P 5.44218
346 1FZQ GDP 5.52486
347 1D8C GLV 5.55556
348 1X8J A3P 5.55556
349 1YQD NAP 5.55556
350 4NST ADP 5.55556
351 2RAB NAD 5.55556
352 1KOL NAD 5.55556
353 5EFQ ADP 5.55556
354 5ETJ IM5 5.55556
355 1Q19 SSC 5.55556
356 5N69 ADP 5.55556
357 1QPB PYM 5.55556
358 1QPB TPP 5.55556
359 1T5C ADP 5.55556
360 2PEZ DAT 5.58659
361 2A92 NAI 5.60748
362 1U0J ADP 5.61798
363 5JE8 NAD 5.62914
364 4NVP 7CH 5.74163
365 2HF9 GSP 5.75221
366 4CVN ADP 5.75916
367 2QUN FUD 5.86207
368 5WS9 ATP 5.8642
369 5WS9 OXL 5.8642
370 2WN6 NDP 5.8642
371 2C42 PYR 5.8642
372 2C42 TPP 5.8642
373 4WZH FMN 5.8642
374 5WKC TP9 5.8642
375 1JGT APC 5.8642
376 6GZD LCI 5.8642
377 2F5Z FAD 5.8642
378 4H03 NAD 5.8642
379 4OHY ANP 5.8642
380 1JGT CMA 5.8642
381 1F9V ADP 5.8642
382 5FI3 NAP 5.8642
383 4GKV NAD 5.8642
384 1T9D FAD 5.8642
385 1B8U NAD 5.8642
386 4BLW SAH 5.88235
387 3NCQ ATP 5.88235
388 4UXL 5P8 5.90062
389 4CLO NAP 5.90278
390 3JQ8 NAP 5.90278
391 4CME NAP 5.90278
392 3JQA NAP 5.90278
393 4CLR NAP 5.90278
394 6F5U CQN 5.95238
395 5XJ7 87O 5.97015
396 2CFA FAD 5.99078
397 4A4X JUP 6.09319
398 3UWV 2PG 6.13027
399 4KQ6 DLZ 6.14525
400 2QEN ADP 6.17284
401 5I0H ADP BEF 6.17284
402 5IE3 OXD 6.17284
403 5IE3 AMP 6.17284
404 3IHG FAD 6.17284
405 4IEE AGS 6.17284
406 1OYY AGS 6.17284
407 4XT8 TMQ 6.20155
408 4XT8 NAP 6.20155
409 4R2M ANP 6.32911
410 5VKT NAP 6.35359
411 5EXE 5SR 6.36943
412 2B3D FAD 6.37255
413 2HJR APR 6.40244
414 3BD9 A3P 6.42857
415 3OCP CMP 6.47482
416 4IP7 FLC 6.48148
417 3V1Y NAD 6.48148
418 4K38 SAM 6.48148
419 1W0J ADP 6.48148
420 2BLE 5GP 6.48148
421 2XTZ GSP 6.48148
422 6BXI ANP 6.48148
423 2J4D MHF 6.48148
424 5MEX PAP 6.52174
425 5MEX SZZ 6.52174
426 4P83 U5P 6.59341
427 1M7G AV2 6.63507
428 1M7G ADP 6.63507
429 5CEO 50D 6.66667
430 1K3A ACP 6.68896
431 1NE6 SP1 6.71378
432 1JJE BYS 6.75676
433 1XKQ NDP 6.78571
434 4TR9 ASP TRP ASN 6.79012
435 1EE0 CAA 6.79012
436 5M7P ADP 6.79012
437 2JHP SAH 6.79012
438 1G3M A3P 6.80272
439 1G3M PCQ 6.80272
440 3I54 CMP 6.82731
441 5OUH L0B 6.82927
442 1E6E FAD 7.03125
443 2B99 RDL 7.05128
444 3BFX A3P 7.09459
445 4D04 FAD 7.09877
446 4D04 NAP 7.09877
447 4U7W NDP 7.09877
448 1QO8 FAD 7.09877
449 1W78 PD8 7.09877
450 1W78 ADP 7.09877
451 3FKQ ATP 7.09877
452 6F5W KG1 7.09877
453 1EJB INJ 7.14286
454 4GC1 MAN MAN 7.24638
455 1YRO GDU 7.31707
456 5UR1 YY9 7.3955
457 2C9O ADP 7.40741
458 5ZBR ANP 7.40741
459 3H4S ADP 7.40741
460 3C6K SPD 7.40741
461 3C6K MTA 7.40741
462 2GKS ADP 7.40741
463 6A20 ADP 7.40741
464 3QV1 NAD 7.40741
465 1U1F 183 7.42188
466 2V7Q ATP 7.53425
467 2CK3 ANP 7.53425
468 2CK3 ADP 7.53425
469 1WVG APR 7.71605
470 1LVK MNT BEF 7.71605
471 3V2U GLA 7.71605
472 1Z6Z NAP 7.80142
473 3T5G GDP 7.89474
474 4J7U NAP 7.98611
475 4J7U YTZ 7.98611
476 2HW1 FRU 8.05369
477 2OFW ADX 8.17308
478 1NF3 GNP 8.20513
479 1KJ1 MAN 8.25688
480 1NE7 AGP 8.3045
481 5WX3 COA 8.33333
482 6ER9 FAD 8.33333
483 2I4I AMP 8.33333
484 5VN0 NAI 8.33333
485 3HWW AKG 8.33333
486 2XT3 ADP 8.33333
487 3RNM FAD 8.62069
488 1TI7 NAP 8.64198
489 2VUT NAD 8.64198
490 5TA6 79D 8.64198
491 3FC2 IBI 8.64198
492 2YJ0 420 8.69565
493 2C94 TSF 8.75
494 5UIV ADP 8.81057
495 1P7T PYR 8.95062
496 5UIU 8CG 8.97833
497 1O3Y GTP 9.03614
498 4YMU ATP 9.09091
499 1S7G NAD 9.09091
500 2CI5 HCS 9.15493
501 5FAW CHT 9.25926
502 5OCM NAP 9.27835
503 2VB6 ADP BEF 9.39597
504 2V5K OXM 9.40767
505 1A4R GNH 9.42408
506 1A4R GDP 9.42408
507 4ITR GDP 9.42408
508 5O74 GDP 9.44444
509 2WMO GTP 9.47368
510 2EXX NAP 9.47712
511 2X77 GDP 9.52381
512 3MVH WFE 9.5679
513 3ZNR NU9 9.5679
514 5W75 SUC 9.5679
515 5JR6 01B PRO PRO ALA NH2 9.5679
516 3SHR CMP 9.699
517 4OIT BMA 9.73451
518 4OIT MAN 9.73451
519 5V2J 7WV 9.87654
520 5V2J UDP 9.87654
521 1UJ2 ADP 9.92064
522 1UJ2 C5P 9.92064
523 3VYW SAM 10.0649
524 2WIC GNP 10.1124
525 3Q9N COA 10.1266
526 1HEX NAD 10.1852
527 5O4J PJL 10.219
528 5O4J SAH 10.219
529 5O4J 9KH 10.219
530 3W5J GDP 10.2941
531 3AFN NAP 10.4651
532 4B5W PYR 10.5469
533 1JG3 ADN 10.6383
534 4JR7 GNP 10.6952
535 4PNI KQQ 10.8025
536 1R9J TPP 11.1111
537 1MV8 NAD 11.1111
538 4ZSY RW2 11.1111
539 4TTQ ATP 11.1628
540 3DUW SAH 11.2108
541 2VHW NAI 11.4198
542 5A0U CHT 11.7284
543 1VKJ A3P 11.7284
544 2BTO GTP 12.037
545 3G6N MET ALA SER 12.0419
546 4KS7 X4Z 12.3288
547 1QF5 GDP 12.3457
548 1QF5 RPL 12.3457
549 4WOP CTP 12.4444
550 3R5W F42 12.5
551 1J99 AND 12.628
552 3TNF GNP 12.6437
553 3ZW2 GLA NAG GAL FUC 12.6437
554 6A1G 9OL 12.963
555 1Y63 ADP 13.0435
556 3KJS NAP 13.2716
557 4L80 OXL 13.5802
558 1RRC ADP 13.9535
559 3NRZ FAD 14.0984
560 5ZW3 SAH 14.2222
561 4RT1 C2E 14.2857
562 6BCB GSP 14.5946
563 3T12 GDP ALF 14.7059
564 1XTT U5P 14.8148
565 4BCM T7Z 14.8855
566 4USI AKG 14.9351
567 1KK8 BEF ADP 15.1079
568 4OSP NAP 15.2091
569 2PL3 ADP 15.2542
570 1GXU 2HP 16.4835
571 2YCJ C2F 16.9742
572 5LB3 ADP 16.9753
573 1HE1 GDP 17.037
574 1AQU A3P 17.1717
575 2F59 INI 17.1975
576 4D0G GTP 17.3913
577 4YJK URA 17.8571
578 4MUV PCG 18.3099
579 3TA2 ATP 18.6441
580 3TA2 AKG 18.6441
581 3ZIA ADP 19.5652
582 3A1S GDP 20.155
583 1UY4 XYP XYP XYP XYP 21.3793
584 5J1S ATP 21.831
585 1KYV RBF 22.0126
586 2PA4 UPG 22.291
587 3E85 BSU 23.4177
588 2ZEJ GDP 23.913
589 3IUY AMP 28.5088
590 4H3P ANP 33.3333
591 1VBH PEP 46.6049
592 1KC7 PPR 47.8395
593 5WRJ A3P 50
Pocket No.: 2; Query (leader) PDB : 2XZ9; Ligand: PYR; Similar sites found with APoc: 100
This union binding pocket(no: 2) in the query (biounit: 2xz9.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 1XG5 NAP 0.716846
2 3ORK AGS 1.60772
3 4G9E C4L 1.79211
4 1BZY IMU 1.84332
5 5FCF GLY GLY GLY 1.85185
6 1JBW ACQ 1.85185
7 2GQS C2R 2.1097
8 1JIL 485 2.16049
9 1PZ1 NAP 2.16049
10 1D2N ANP 2.20588
11 2QFY AKG 2.34192
12 4YCA NDP 2.38095
13 4RPL FAD 2.46914
14 4RPL 3UC 2.46914
15 1GP2 GDP 2.46914
16 1D4D FAD 2.46914
17 4OTH DRN 2.46914
18 2AWN ADP 2.46914
19 3EPO MP5 2.46914
20 1LQA NDP 2.46914
21 3NOJ PYR 2.52101
22 4J4H 1J1 2.7027
23 4PLT NAI 2.77778
24 4S28 AIR 2.77778
25 4S28 SAH 2.77778
26 2NAD NAD 2.77778
27 1RPN NDP 2.77778
28 3RK0 AMP 2.95359
29 2HK5 1BM 2.96296
30 5YVT NAI 3.08642
31 3WXB NDP 3.22581
32 3X0V FAD 3.39506
33 2I7C AAT 3.53357
34 1VHT BA3 3.66972
35 4XWM CBI 3.7037
36 1OX5 1PR 3.7037
37 4ZY1 4U5 3.7037
38 4Y0X ADP 3.7037
39 6AMI TRP 3.7037
40 1UNH IXM 3.76712
41 2WT9 NIO 3.82979
42 3CX8 GSP 3.94089
43 1Q9I TEO 4.01235
44 1Q9I FAD 4.01235
45 2R5C C6P 4.01235
46 2R5E QLP 4.01235
47 5VC5 96M 4.15225
48 4REL KMP 4.32099
49 5ZBC FAD 4.32099
50 4B0T ADP 4.32099
51 2Q46 NAP 4.34783
52 5G3U FDA 4.62963
53 2WU6 DKI 4.62963
54 5TPR NAD 4.62963
55 1OUK 084 5.24691
56 1SAY PYR 5.24691
57 1BWV CAP 5.24691
58 1RHC F42 ACN 5.24691
59 4Z87 5GP 5.24691
60 1UNB AKG 5.46624
61 1UNB PN1 5.46624
62 3GE7 AFQ 5.55556
63 4ZLA BES 5.55556
64 4GUS FAD 5.64516
65 5E5U MLI 5.68182
66 1T9D PYD 5.8642
67 1T9D P25 5.8642
68 5WKC AUJ 5.8642
69 4BLW AMP 5.88235
70 1T3Q FAD 5.95238
71 6G9I CXX 5.95238
72 1NST A3P 6.48148
73 5DK4 5BX 6.48148
74 5DK4 ATP 6.48148
75 3I59 N6R 6.82731
76 3I59 N6S 6.82731
77 2OO0 PLP 7.09877
78 5OYA CAP 7.40741
79 4E1Z 0MX 7.56014
80 2IXB A2G 7.71605
81 2IVD FAD 7.71605
82 1O94 ADP 7.8125
83 4YKG FAD 8.02469
84 1IR1 CAP 8.13008
85 3DAK ANP 8.27586
86 5JCA NDP 8.33333
87 2NPX NAD 8.33333
88 3VX3 ADP 8.87097
89 4LRJ ANP 8.87574
90 5EYP LOC 9.46746
91 2PX8 SAH 11.1524
92 5YJS SAL 12.6543
93 3IIJ ADP 13.8889
94 2GV8 FAD 14.5062
95 2GVC FAD 14.5062
96 1VQW FAD 14.5062
97 3AD8 NAD 15.7635
98 1H82 FAD 17.284
99 1H82 GZZ 17.284
100 1GK8 CAP 25.7143
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