Receptor
PDB id Resolution Class Description Source Keywords
2XI7 2.2 Å EC: 7.-.-.- N-TERMINAL ENDONUCLEASE DOMAIN OF LA CROSSE VIRUS L-PROTEIN BUNYAVIRUS LA CROSSE TRANSFERASE ENDONUCLEASE
Ref.: BUNYAVIRIDAE RNA POLYMERASES (L-PROTEIN) HAVE AN N-INFLUENZA-LIKE ENDONUCLEASE DOMAIN, ESSENTIAL FOR V DEPENDENT TRANSCRIPTION. PLOS PATHOG. V. 6 1101 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MN A:1184;
A:1185;
B:1184;
B:1185;
C:1184;
C:1185;
D:1184;
D:1185;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
54.938 Mn [Mn+2...
XI7 A:1186;
B:1186;
C:1186;
D:1186;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
192.168 C10 H8 O4 c1ccc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2XI7 2.2 Å EC: 7.-.-.- N-TERMINAL ENDONUCLEASE DOMAIN OF LA CROSSE VIRUS L-PROTEIN BUNYAVIRUS LA CROSSE TRANSFERASE ENDONUCLEASE
Ref.: BUNYAVIRIDAE RNA POLYMERASES (L-PROTEIN) HAVE AN N-INFLUENZA-LIKE ENDONUCLEASE DOMAIN, ESSENTIAL FOR V DEPENDENT TRANSCRIPTION. PLOS PATHOG. V. 6 1101 2010
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 293 families.
1 2XI7 - XI7 C10 H8 O4 c1ccc(cc1)....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 250 families.
1 2XI7 - XI7 C10 H8 O4 c1ccc(cc1)....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 204 families.
1 2XI7 - XI7 C10 H8 O4 c1ccc(cc1)....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: XI7; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 XI7 1 1
2 HTK 0.4375 0.64
3 GXD 0.418605 0.730769
4 GXG 0.409091 0.730769
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2XI7; Ligand: XI7; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2xi7.bio1) has 7 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 2XI7; Ligand: XI7; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2xi7.bio1) has 7 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 2XI7; Ligand: XI7; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 2xi7.bio1) has 7 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 2XI7; Ligand: XI7; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 2xi7.bio1) has 7 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 2XI7; Ligand: XI7; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 2xi7.bio1) has 7 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 2XI7; Ligand: XI7; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 2xi7.bio1) has 7 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 2XI7; Ligand: XI7; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 2xi7.bio1) has 7 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 2XI7; Ligand: XI7; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 2xi7.bio1) has 7 residues
No: Leader PDB Ligand Sequence Similarity
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