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Receptor
PDB id Resolution Class Description Source Keywords
2X77 2.1 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF LEISHMANIA MAJOR ADP RIBOSYLATION FACTOR-LIKE 1. LEISHMANIA MAJOR GTP-BINDING PROTEIN SMALL GTPASE NUCLEOTIDE-BINDING
Ref.: CRYSTAL STRUCTURE OF LEISHMANIA MAJOR ADP RIBOSYLATION FACTOR-LIKE 1 AND A CLASSIFICATION OF RELATED GTPASE FAMILY MEMBERS IN THIS KINETOPLASTID. MOL.BIOCHEM.PARASITOL. V. 174 141 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP A:188;
B:188;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
MG A:189;
B:189;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2X77 2.1 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF LEISHMANIA MAJOR ADP RIBOSYLATION FACTOR-LIKE 1. LEISHMANIA MAJOR GTP-BINDING PROTEIN SMALL GTPASE NUCLEOTIDE-BINDING
Ref.: CRYSTAL STRUCTURE OF LEISHMANIA MAJOR ADP RIBOSYLATION FACTOR-LIKE 1 AND A CLASSIFICATION OF RELATED GTPASE FAMILY MEMBERS IN THIS KINETOPLASTID. MOL.BIOCHEM.PARASITOL. V. 174 141 2010
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 2X77 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 2X77 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1RRG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 1HUR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 1O3Y - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
5 1YZG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
6 3N5C - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 1E0S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
8 3AQ4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
9 4Y0V - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
10 4YLG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
11 1MR3 - G3D C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (19)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 204 families.
1 4V0K - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 4V0L - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
3 2X77 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 1RRG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 1HUR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
6 1O3Y - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
7 1FZQ Kd = 24 nM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
8 1Z6Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
9 1ZJ6 - G3D C10 H16 N5 O14 P3 c1nc2c(n1[....
10 1YZG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
11 3N5C - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
12 1E0S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
13 1ZD9 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
14 2AL7 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
15 3AQ4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
16 4Y0V - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
17 4YLG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
18 1MR3 - G3D C10 H16 N5 O14 P3 c1nc2c(n1[....
19 4BAS - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 161
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 9GM 0.839506 0.973684
6 GNP 0.839506 0.973684
7 G 0.828947 0.986486
8 5GP 0.828947 0.986486
9 G1R 0.82716 0.986667
10 GCP 0.82716 0.973684
11 GSP 0.817073 0.948718
12 GAV 0.797619 0.961039
13 GMV 0.792683 0.973684
14 G2P 0.77381 0.961039
15 G2R 0.770115 0.961039
16 GP2 0.756098 0.961039
17 GDC 0.747253 0.961039
18 GKE 0.747253 0.961039
19 GDD 0.747253 0.961039
20 GPG 0.741573 0.961039
21 G3D 0.732558 0.986486
22 ALF 5GP 0.729412 0.888889
23 Y9Z 0.728261 0.902439
24 G5P 0.723404 0.973684
25 GFB 0.72043 0.961039
26 GTG 0.72043 0.936709
27 GDR 0.72043 0.961039
28 G4P 0.715909 0.986486
29 G3A 0.712766 0.973684
30 6CK 0.712766 0.936709
31 GDP AF3 0.7 0.888889
32 ALF GDP 0.7 0.888889
33 GDP ALF 0.7 0.888889
34 YGP 0.698925 0.901235
35 GKD 0.697917 0.961039
36 JB2 0.697917 0.961039
37 GDX 0.690722 0.973684
38 GPD 0.690722 0.925
39 GMP 0.684211 0.88
40 0O2 0.666667 0.986486
41 JB3 0.656863 0.948718
42 NGD 0.650485 0.961039
43 DGI 0.636364 0.923077
44 GDP 7MG 0.636364 0.911392
45 U2G 0.634615 0.936709
46 GPX 0.634409 0.946667
47 G G 0.632653 0.948052
48 IDP 0.632184 0.972973
49 2MD 0.632075 0.891566
50 CAG 0.62963 0.880952
51 CG2 0.622642 0.936709
52 FEG 0.619048 0.879518
53 MGD 0.614679 0.891566
54 ZGP 0.613208 0.869048
55 GH3 0.612903 0.973333
56 3GP 0.611765 0.946667
57 MD1 0.607143 0.891566
58 PGD 0.59292 0.925
59 DGT 0.591398 0.923077
60 BGO 0.588785 0.924051
61 TPG 0.582609 0.840909
62 DBG 0.582609 0.948718
63 2GP 0.574713 0.96
64 FE9 0.570175 0.776596
65 GCP G 0.56 0.921053
66 A G 0.553571 0.935065
67 G A A A 0.553571 0.923077
68 MGP 0.553191 0.961039
69 U A G G 0.548673 0.935065
70 G4M 0.548387 0.880952
71 6G0 0.547368 0.961039
72 G1R G1R 0.542373 0.924051
73 P2G 0.527473 0.883117
74 PGD O 0.525 0.850575
75 ADP 0.522222 0.92
76 R5I 0.520833 0.946667
77 R7I 0.520833 0.946667
78 GGM 0.517544 0.901235
79 DGP 0.516484 0.910256
80 DG 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G U 0.513274 0.9
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 AKW 0.504425 0.890244
86 G C 0.504348 0.9
87 GPC 0.491525 0.879518
88 G7M 0.483871 0.948052
89 6AD 0.479592 0.841463
90 ATP 0.473684 0.92
91 HEJ 0.473684 0.92
92 G2Q 0.471154 0.961039
93 5FA 0.46875 0.92
94 AQP 0.46875 0.92
95 GTA 0.468468 0.936709
96 7DD 0.468085 0.906667
97 G G G RPC 0.466102 0.875
98 SGP 0.463158 0.82716
99 01G 0.462963 0.902439
100 HFD 0.459184 0.873418
101 B4P 0.457447 0.894737
102 AP5 0.457447 0.894737
103 A2D 0.456522 0.894737
104 6YZ 0.455446 0.896104
105 G G G C 0.455285 0.9125
106 5GP 5GP 0.454545 0.883117
107 ANP 0.454545 0.896104
108 ACQ 0.454545 0.896104
109 AT4 0.452632 0.884615
110 A G C C 0.451613 0.911392
111 APC G U 0.45082 0.886076
112 PRT 0.449541 0.959459
113 G U34 0.449153 0.888889
114 DG DG 0.448598 0.865854
115 ITT 0.447917 0.868421
116 BA3 0.446809 0.894737
117 C2E 0.444444 0.921053
118 PCG 0.444444 0.933333
119 35G 0.444444 0.933333
120 MGO 0.441176 0.864198
121 AN2 0.4375 0.907895
122 G C C C 0.4375 0.924051
123 M33 0.43299 0.883117
124 UCG 0.429688 0.911392
125 A G U 0.42963 0.888889
126 ACP 0.428571 0.896104
127 MGQ 0.424528 0.935897
128 AR6 0.424242 0.894737
129 7DT 0.424242 0.906667
130 APR 0.424242 0.894737
131 93A 0.42268 0.833333
132 A4P 0.420168 0.869048
133 G8D 0.42 0.875
134 AD9 0.42 0.896104
135 SAP 0.42 0.873418
136 AGS 0.42 0.873418
137 CA0 0.418367 0.896104
138 ATF 0.417476 0.884615
139 AGO 0.414634 0.888889
140 A G U U 0.414286 0.888889
141 NIA 0.413043 0.82716
142 MGV 0.412844 0.890244
143 TAT 0.411765 0.884615
144 T99 0.411765 0.884615
145 ADQ 0.411215 0.871795
146 A1R 0.411215 0.839506
147 RGT 0.410714 0.909091
148 CGP 0.409836 0.86747
149 C1Z 0.409091 0.986486
150 A 0.408602 0.893333
151 AMP 0.408602 0.893333
152 UP5 0.40678 0.873418
153 AMZ 0.406593 0.918919
154 C2R 0.406593 0.906667
155 JBT 0.405882 0.778947
156 A22 0.40566 0.907895
157 25L 0.405405 0.907895
158 ADX 0.40404 0.809524
159 8OD 0.401961 0.946667
160 50T 0.4 0.883117
161 4TC 0.4 0.851852
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2X77; Ligand: GDP; Similar sites found with APoc: 565
This union binding pocket(no: 1) in the query (biounit: 2x77.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 1CLU DBG None
2 3KUD GDP None
3 1UJ2 ADP None
4 1UJ2 C5P None
5 1GXU 2HP None
6 2F3R G5P None
7 4KVX ACO None
8 4TTQ ATP 1.0582
9 4QM7 GTP 1.16959
10 1SKQ GDP 1.5873
11 1LVG ADP 1.5873
12 2ZFI ADP 1.5873
13 1ION ADP 1.5873
14 5E5U MLI 1.5873
15 3QVV 3QV 1.5873
16 3QVV A3P 1.5873
17 2GWH A3P 1.5873
18 1AQU A3P 1.5873
19 1F2U ATP 2.02703
20 6BVJ GNP 2.1164
21 6BVK GNP 2.1164
22 6BVI GNP 2.1164
23 6D5H GNP 2.1164
24 6BVL GNP 2.1164
25 6D5E GNP 2.1164
26 6D5G GNP 2.1164
27 6D5J GNP 2.1164
28 1NVV GNP 2.1164
29 6D55 GNP 2.1164
30 6BVM GNP 2.1164
31 6D5L GNP 2.1164
32 6D56 GNP 2.1164
33 6D59 GNP 2.1164
34 6D5M GNP 2.1164
35 6D5V GNP 2.1164
36 3BOS CDP 2.1164
37 2Z5F A3P 2.1164
38 1CJW COT 2.40964
39 2RCN GDP 2.6455
40 1B0U ATP 2.6455
41 2JLR ANP 2.6455
42 1Z83 AP5 2.6455
43 4PX9 ADP 2.6455
44 3B7G ANP 2.6455
45 4R2I ANP 2.6455
46 2WZF BGC 2.6455
47 1G8K MGD 2.6455
48 4PJ3 ANP 2.6455
49 5H4S RAM 2.6455
50 2I4I AMP 2.6455
51 6AIC AMP 2.6455
52 2VWT PYR 2.6455
53 4UXH T5A 2.71739
54 3TK1 GDP 3.1746
55 5KUT GDP 3.1746
56 3E70 GDP 3.1746
57 5L3W GDP 3.1746
58 1YQT ADP 3.1746
59 3HU3 AGS 3.1746
60 4NE2 SH2 3.1746
61 4NE2 ADP 3.1746
62 5GVR LMR 3.1746
63 3FYH ADP 3.1746
64 3QXC ATP 3.1746
65 1XX6 ADP 3.1746
66 1DAK ADP 3.1746
67 1DAK DPU 3.1746
68 1G6O ADP 3.1746
69 2GDJ ANP 3.1746
70 5YV5 ADP 3.1746
71 1KK8 BEF ADP 3.1746
72 5LLB 6YZ 3.1746
73 5I0H ADP BEF 3.1746
74 3BFX A3P 3.1746
75 1D2N ANP 3.1746
76 4QRH 0O2 3.1746
77 4KBF AMP 3.1746
78 3MGB PAP 3.1746
79 3CV2 OXL 3.1746
80 2QQ0 TMP 3.26087
81 2QQ0 ADP 3.26087
82 2QQ0 ANP 3.26087
83 2QQ0 THM 3.26087
84 2QN6 GDP 3.7037
85 2VVG ADP 3.7037
86 5KSP GDP 3.7037
87 5KSZ GCP 3.7037
88 3A4M ADP 3.7037
89 4RD0 GDP 3.7037
90 3ZQ6 ADP ALF 3.7037
91 1SVM ATP 3.7037
92 4BFW ZVW 3.7037
93 2QZ4 ADP 3.7037
94 1RRC ADP 3.7037
95 1QF9 C5P 3.7037
96 1QF9 ALF 3.7037
97 1QF9 ADP 3.7037
98 1H65 GDP 3.7037
99 1XKV ATP 3.7037
100 3DKP ADP 3.7037
101 4FCW ADP 3.7037
102 1U0J ADP 3.7037
103 2B8T THM 3.7037
104 2ZE7 DST 3.7037
105 2ZE7 AMP 3.7037
106 2C9O ADP 3.7037
107 5EP2 AZU 3.7037
108 2JJK R15 3.7037
109 3BER AMP 3.7037
110 1D8T GDP 4.2328
111 2HCJ GDP 4.2328
112 2BVN GNP 4.2328
113 5ZXD ATP 4.2328
114 1G3Q ADP 4.2328
115 3DC4 ADP 4.2328
116 1W5T ANP 4.2328
117 1IN4 ADP 4.2328
118 3VM7 GLC 4.2328
119 4A4Z ANP 4.2328
120 5WRI A3P 4.2328
121 1NST A3P 4.2328
122 4ZDJ UTP 4.2328
123 4E5N NAD 4.2328
124 1W5T ADP 4.2328
125 1X8J A3P 4.2328
126 1G3M PCQ 4.2328
127 1G3M A3P 4.2328
128 1Q20 A3P 4.2328
129 1Q20 PLO 4.2328
130 2C5L GTP 4.2735
131 5WRJ A3P 4.62046
132 1SVI GDP 4.7619
133 2C78 GNP 4.7619
134 5L3V GDP 4.7619
135 1JI0 ATP 4.7619
136 2C77 GNP 4.7619
137 1E2K TMC 4.7619
138 1V8K ANP 4.7619
139 1XP8 AGS 4.7619
140 3ZFD ANP 4.7619
141 1UKZ ADP 4.7619
142 5L3S GNP 4.7619
143 1AKY AP5 4.7619
144 4PFO ADP 4.7619
145 3QKT ANP 4.7619
146 5LB3 ADP 4.7619
147 1T5C ADP 4.7619
148 4HSE ADP 4.7619
149 1FP6 ADP 4.7619
150 2IS6 ADP 4.7619
151 4GBM A3P 4.7619
152 4HUT ATP 4.7619
153 5L3S G 4.7619
154 2VBQ BSJ 4.84848
155 2ZEJ GDP 4.8913
156 5GLN XYS 4.94186
157 3LN9 FLC 5.03597
158 2AWN ADP 5.29101
159 4KFU ACP 5.29101
160 3UIE ANP 5.29101
161 1QF5 GDP 5.29101
162 1QF5 RPL 5.29101
163 6B8B ADP 5.29101
164 2YOH WMJ 5.29101
165 3FB4 AP5 5.29101
166 3NHB ADP 5.29101
167 4X8O AP5 5.29101
168 2NCD ADP 5.29101
169 4MKF AP5 5.29101
170 5ZB0 TYD 5.29101
171 5ZB0 ADP 5.29101
172 1QHH ATP 5.29101
173 4Q1A UDP 5.71429
174 4Q1A 2XZ 5.71429
175 3KTA AP5 5.78035
176 1XEX ATP 5.81395
177 4NCN GTP 5.82011
178 5U32 GDP 5.82011
179 2QEN ADP 5.82011
180 5UIV ADP 5.82011
181 1ZIN AP5 5.82011
182 2DPY ADP 5.82011
183 3FVQ ATP 5.82011
184 1G41 ADP 5.82011
185 1R6B ADP 5.82011
186 1OS1 ATP 5.82011
187 1OS1 PYR 5.82011
188 5Y6N ADP 5.82011
189 1JJV ATP 5.82011
190 2BHZ MAL 5.82011
191 2ORV 4TA 5.82011
192 5TIV A3P 5.82011
193 1VKJ A3P 5.82011
194 4LIK CIT 5.82011
195 3IUY AMP 5.82011
196 2V5K OXM 5.82011
197 1J99 AND 5.82011
198 1TT8 PHB 6.09756
199 3IIJ ADP 6.11111
200 3DDC GNP 6.13497
201 1WQ1 GDP 6.34921
202 4LC1 GDP 6.34921
203 1KK1 GNP 6.34921
204 2W58 ADP 6.34921
205 5I34 GDP 6.34921
206 1SQ5 ADP 6.34921
207 4GOX A3P 6.34921
208 4IEE AGS 6.34921
209 4TMK T5A 6.34921
210 6B4K ANP 6.34921
211 2IXE ATP 6.34921
212 4LJ9 ACP 6.34921
213 2D7D ADP 6.34921
214 1I0B PEL 6.34921
215 5MEX SZZ 6.34921
216 1B7T ADP 6.41026
217 3Q72 GNP 6.62651
218 4YMU ATP 6.66667
219 2RGX AP5 6.79612
220 4MKG AP5 6.87831
221 2QG6 NMN 6.87831
222 1S3G AP5 6.87831
223 1LVK MNT BEF 6.87831
224 5X40 ACP 6.87831
225 5Z69 AGS 6.87831
226 4ZNL BEF ADP 6.87831
227 5ZBR ANP 6.87831
228 4WZ6 ATP 6.87831
229 2XAU ADP 6.87831
230 1F5N GNP 6.87831
231 1VHT BA3 6.88073
232 4U5X GNP 7.30337
233 1G7S GDP 7.40741
234 3W5J GDP 7.40741
235 1M7G AV2 7.40741
236 4WZA ACP 7.40741
237 4WZA ADP 7.40741
238 3DEF GDP 7.40741
239 4IDN GNP 7.40741
240 2XTN GTP 7.40741
241 4D81 ADP 7.40741
242 3DZD ADP 7.40741
243 6DEF GCP 7.40741
244 1T8U UAP SGN IDS SGN 7.40741
245 1T8U A3P 7.40741
246 1M7G ADP 7.40741
247 1M7G ADX 7.40741
248 3TMK T5A 7.40741
249 5MZN ADP 7.40741
250 4OI4 ATP 7.82609
251 1BG2 ADP 7.93651
252 1OXV ANP 7.93651
253 2WHX ADP 7.93651
254 5TSH ADP 7.93651
255 4XTR ATP 7.93651
256 5TSH ANP 7.93651
257 4XVU ATP 7.93651
258 4XTR ADP 7.93651
259 2JAQ DCP 7.93651
260 2ZPA ADP 7.93651
261 2CHG ANP 7.93651
262 2WOJ ADP ALF 7.93651
263 3ZS9 ADP ALF 7.93651
264 3TBK ANP 7.93651
265 5ICE SAH 7.93651
266 4BQS ADP 7.95455
267 4BQS K2Q 7.95455
268 1LFD GNP 8.04598
269 1GOJ ADP 8.46561
270 4P4T GDP 8.46561
271 2ZR9 DTP 8.46561
272 4CVN ADP 8.46561
273 1W0J ADP 8.46561
274 3VX3 ADP 8.46561
275 4IHQ ADP 8.46561
276 1W4R TTP 8.46561
277 4R43 GDP 8.46561
278 5BQ5 ADP BEF 8.46561
279 2FAH GDP 8.46561
280 1W0J ADP BEF 8.46561
281 2ZJ5 ADP 8.46561
282 1G7C 5GP 8.51064
283 1RJ9 GCP 8.55263
284 1BO4 COA 8.92857
285 1TQ4 GDP 8.99471
286 1DAR GDP 8.99471
287 1XMV ADP 8.99471
288 1CR1 TTP 8.99471
289 4NU0 AP5 8.99471
290 5N69 ADP 8.99471
291 5BYK OAQ 8.99471
292 5BYK A3P 8.99471
293 2FSH ANP 8.99471
294 2CZL TLA 8.99471
295 2IYL GDP 9.15493
296 1MKY GDP 9.52381
297 5AK0 8V1 9.52381
298 2GKS ADP 9.52381
299 2BEK ATP 9.52381
300 4WOP CTP 9.52381
301 2GMV UN8 9.52381
302 1NHX FTB 9.52381
303 1NHX PEP 9.52381
304 2GMV PEP 9.52381
305 2O0J ADP 9.52381
306 5YT0 GDP 10.0529
307 5FG3 GDP 10.0529
308 4HDO GNP 10.0529
309 1GUA GNP 10.0529
310 3PQC GDP 10.0529
311 1KAO GDP 10.0529
312 4LPS GDP 10.0529
313 3COB ADP 10.0529
314 1NF3 GNP 10.0529
315 1F9V ADP 10.0529
316 1OFH ADP 10.0529
317 1Z6T ADP 10.0529
318 1IHU AF3 10.0529
319 1IHU ADP 10.0529
320 3ITJ CIT 10.0529
321 4WZ8 3W7 10.0529
322 2PL3 ADP 10.1695
323 5UPK GNP 10.4167
324 1JJ7 ADP 10.582
325 4U00 ADP 10.582
326 3B5J 12D 10.582
327 3P4X ADP 10.582
328 3FWY ADP 10.582
329 1NJF ADP 10.582
330 1NJF AGS 10.582
331 5NM7 GLY 10.582
332 1ZUI SKM 10.7143
333 3BFV ADP 11.0701
334 2CDN ADP 11.1111
335 3H86 AP5 11.1111
336 3QFA FAD 11.2069
337 2Y65 ADP 11.6402
338 4AG5 ADP 11.6402
339 1P9B GDP 11.6402
340 4ZG4 VO4 ADP 11.6402
341 6CS8 F9Y 11.6402
342 2Q2Y ADP 11.6402
343 2Q2Y MKR 11.6402
344 2VHJ ADP 11.6402
345 1D2E GDP 12.1693
346 1IWE IMP 12.1693
347 3BD9 A3P 12.1693
348 1KO8 6PG 12.5714
349 1YRB GDP 12.6984
350 3H4S ADP 12.6984
351 4FRZ ADP 12.6984
352 4IOK XPO 12.6984
353 4IOK ADP 12.6984
354 2VB6 ADP BEF 12.6984
355 2B8W ALF 5GP 12.6984
356 1I4D GDP 13.2275
357 2J0V GDP 13.2275
358 1WF3 GNP 13.2275
359 4B47 GDP 13.7566
360 1DS6 GDP 13.7566
361 1RYH GNP 13.7566
362 2FJU GSP 13.7566
363 2W2X GSP 13.7566
364 1G4U GDP 13.7566
365 2KIN ADP 13.7566
366 1HE1 GDP 13.7566
367 3SBD GNP 13.7566
368 5EXT ADP 13.7566
369 1MH1 GNP 14.2857
370 1NN5 ANP 14.2857
371 1NN5 2DT 14.2857
372 1G6H ADP 14.2857
373 3KJI ADP 14.2857
374 3RC3 ANP 14.2857
375 3R7F CP 14.2857
376 2WKQ GTP 14.8148
377 1E96 GTP 14.8148
378 2XT3 ADP 14.8148
379 4TL6 ANP 14.8148
380 2CE7 ADP 14.8148
381 1FNN ADP 14.8148
382 4YS0 ADP 14.8148
383 4HI0 GDP 15.3439
384 1OE0 TTP 15.3439
385 3Q85 GNP 15.3846
386 6C90 ADP 15.3846
387 1PUJ GNP 15.873
388 4DID GDP 15.873
389 2OG2 MLI 15.873
390 3B9Q MLI 15.873
391 1YTM ATP 15.873
392 5L3R GCP 15.873
393 1OYY AGS 15.873
394 3RLF ANP 15.873
395 2PEZ GGZ 16.2011
396 2PEZ DAT 16.2011
397 1X1R GDP 16.2921
398 5BN3 ADP 16.4021
399 2V7Q ATP 16.4384
400 2CK3 ANP 16.4384
401 2CK3 ADP 16.4384
402 2V7Q ADP 16.4384
403 1A4R GNH 16.9312
404 1A4R GDP 16.9312
405 5UQW GDP 16.9312
406 5OCG GNP 16.9312
407 5TB5 GDP 17.2973
408 5TAR GDP 17.2973
409 3WXM GTP 17.4603
410 2NGR GDP 17.4603
411 1GRN GDP 17.4603
412 4ITR GDP 17.4603
413 2OFW ADX 17.4603
414 2UZI GTP 17.5439
415 3EC1 GDP 17.9894
416 6G14 G4P 17.9894
417 3T12 GDP ALF 17.9894
418 5XKT GNP 17.9894
419 3T1O GDP 17.9894
420 2XTZ GSP 17.9894
421 1P72 ADP 17.9894
422 2J5V PCA 17.9894
423 6FA4 GNP 18.4971
424 4D0N GDP 18.5185
425 1CXZ GSP 18.5185
426 1W7J ADP BEF 18.5185
427 5O2T GSP 18.9349
428 2GJ8 ALF GDP 19.0476
429 3ZIA ATP 19.0476
430 3ZIA ADP 19.0476
431 1NY5 ADP 19.0476
432 5WLB GNP 19.2771
433 5UWP GNP 19.5767
434 4HAT GNP 19.5767
435 5DIF GNP 19.5767
436 6CIT GNP 19.5767
437 5UWW GNP 19.5767
438 5UWU GNP 19.5767
439 5UWO GNP 19.5767
440 5DHF GNP 19.5767
441 5UWS GNP 19.5767
442 3GJ3 GDP 19.5767
443 5UWT GNP 19.5767
444 5UWH GNP 19.5767
445 3GJ0 GDP 19.5767
446 3GJ4 GDP 19.5767
447 3M1I GTP 19.5767
448 3GJ7 GDP 19.5767
449 3GJ8 GDP 19.5767
450 3GJ5 GDP 19.5767
451 5BXQ GDP 19.5767
452 3CH5 GDP 19.5767
453 5UWI GNP 19.5767
454 1IBR GNP 19.5767
455 5UWJ GNP 19.5767
456 5DI9 GNP 19.5767
457 2GK6 ADP 19.5767
458 2D2F ADP 19.5767
459 3FIU POP 19.5767
460 1WA5 GTP 19.8864
461 5CK5 GDP 20.1058
462 2CJW GDP 20.1058
463 1VG0 GDP 20.1058
464 1OW3 GDP 20.1058
465 1Z0K GTP 20.1058
466 5HPY GDP 20.1058
467 1VG8 GNP 20.1058
468 1TX4 ALF GDP 20.1058
469 1VG1 GDP 20.5405
470 1VG9 GDP 20.5405
471 1M7B GTP 20.6349
472 2BME GNP 20.6349
473 5Z2M GTP 21.0227
474 1Z2A GDP 21.164
475 4K81 GTP 21.164
476 2BIF ANP 21.164
477 2BIF SIN 21.164
478 2HT6 GDP 21.2644
479 3MJH GTP 21.4286
480 1TU3 GNP 21.6374
481 5HCN GCP 21.6931
482 5IRC GDP 21.6931
483 1L2T ATP 21.6931
484 1R2Q GNP 21.7647
485 1KY3 GDP 22.2222
486 3REF GDP 22.2222
487 1GOT GDP 22.7513
488 3RWO GDP 23.2804
489 3MD0 GDP 23.8095
490 1TAD GDP 23.8095
491 1TAD ALF 23.8095
492 4NON GDP 23.8095
493 2GCO GNP 24.3386
494 4R98 GNH 24.3386
495 2GCN GDP 24.3386
496 1FQJ GDP 24.3386
497 1FQK GDP 24.3386
498 6AU6 GDP 24.8677
499 1BH2 GSP 24.8677
500 1CS4 GSP 24.8677
501 6CRK GDP 24.8677
502 1Y3A GDP 24.8677
503 2OM2 GDP 24.8677
504 2WIC GNP 24.8677
505 1GP2 GDP 24.8677
506 5KDO GDP 24.8677
507 2ODE ALF GDP 24.8677
508 1K6M AGS 24.8677
509 3CX8 GSP 25.3968
510 3AB3 GDP 25.3968
511 2HV8 GTP 25.3968
512 1GWN GTP 25.3968
513 2D7C GTP 25.3968
514 1SVK ALF GDP 25.3968
515 4H1V GNP 25.9259
516 3QF7 ANP 26
517 3T5G GDP 27.6243
518 6BSX GDP 28.0899
519 6BSX E7S 28.0899
520 2WJH GDP 28.5714
521 2WJH FLC 28.5714
522 2WJG GDP 28.7234
523 2F9L GDP 29.1005
524 3QBT GNP 29.3103
525 5HR5 ADP 29.6296
526 2A9K GDP 30.1587
527 1YZQ GNP 30.1587
528 1X6V ADP 30.1587
529 1D5C GDP 30.2469
530 4DCT GDP 30.6878
531 1ZC3 GNP 31.4286
532 1S8F GDP 31.6384
533 5O74 GDP 31.746
534 1Z06 GNP 32.2751
535 1NRJ GTP 32.2751
536 4QOS ADP 32.2751
537 1Z0J GTP 32.3529
538 2FH5 GTP 32.8042
539 2HF9 GSP 32.8042
540 1YVD GNP 33.1361
541 5M04 GDP 33.3333
542 1U8Z GDP 33.3333
543 5UWR GNP 33.3333
544 1OIX GDP 33.8624
545 1Z0A GDP 33.8624
546 2G77 GDP 33.8624
547 2G77 AF3 33.8624
548 1OIV GDP 34.3915
549 5XC5 GTP 34.6591
550 4C4P GNP 35.2601
551 3BC1 GNP 35.4497
552 1Z0F GDP 35.9788
553 3A1S GDP 35.9788
554 3RAB GNP 36.0947
555 1YZN GNP 36.2162
556 1EK0 GNP 36.4706
557 1KMQ GNP 37.037
558 2A5J GDP 38.6243
559 2FFQ GSP 39.1813
560 2BCG GDP 39.6825
561 5UWQ GNP 40.9091
562 1F6B GDP 41.7989
563 1Z08 GNP 43.5294
564 1G16 GDP 44.1176
565 1M2O GNP 49.7355
Pocket No.: 2; Query (leader) PDB : 2X77; Ligand: GDP; Similar sites found with APoc: 39
This union binding pocket(no: 2) in the query (biounit: 2x77.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 1QSN COA None
2 1PUA COA None
3 1Q2D COA None
4 1QSR ACO None
5 2JDC CAO 2.05479
6 1KUV CA5 2.1164
7 2ZFZ ARG 2.53165
8 2A2C NG1 2.6455
9 2A2C ADP 2.6455
10 5GUD NDP 2.6455
11 4KOT CE3 3.08642
12 2ZPT A3P 3.1746
13 5KF9 ACO 3.1746
14 4DDY DN6 3.7037
15 1S7N COA 3.84615
16 4R3L COA 4.62428
17 2PO3 T4K 4.7619
18 3F8K COA 5
19 1Z0N BCD 5.20833
20 4NSQ COA 5.29101
21 3D2M COA 5.29101
22 1Q19 APC 5.29101
23 1QHG ATP 5.29101
24 4QC6 30N 5.58659
25 4H6U ACO 5.82011
26 1CM0 COA 5.95238
27 5MEX PAP 6.34921
28 4ITM ATP 6.34921
29 2PZ8 APC 6.34921
30 2ZPA ACO 7.93651
31 2ZW5 COA 8.46561
32 4AVB ACO 8.46561
33 2XZ9 PYR 9.52381
34 4PSW COA 12.6984
35 1BOB ACO 12.6984
36 2FNU PMP UD1 13.2275
37 5HGZ ACO 15.3439
38 5HH0 COA 15.3439
39 1U1I NAD 21.6931
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