-->
Receptor
PDB id Resolution Class Description Source Keywords
2W83 1.93 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE ARF6 GTPASE IN COMPLEX WITH A SPECIFIC EFFECTOR, JIP4 HOMO SAPIENS GOLGI APPARATUS PROTEIN TRANSPORT ER-GOLGI TRANSPORT ARF GTPASE EFFECTOR MYRISTATE CYTOPLASM NUCLEOTIDE-BINDING ALTERNATIVE SPLICING GTP-BINDING PHOSPHOPROTEIN HETEROTETRAMER TRANSPORT COILED-COIL LIPOPROTEIN COILED COIL
Ref.: THE STRUCTURAL BASIS OF ARF EFFECTOR SPECIFICITY: THE CRYSTAL STRUCTURE OF ARF6 IN A COMPLEX WITH JIP4. EMBO J. V. 28 2835 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DIO A:1175;
C:1453;
C:1454;
E:1175;
E:1176;
E:1177;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
submit data
88.105 C4 H8 O2 C1COC...
GOL A:1176;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
GTP A:1173;
B:1173;
E:1173;
Valid;
Valid;
Valid;
none;
none;
none;
submit data
523.18 C10 H16 N5 O14 P3 c1nc2...
MG A:1174;
B:1174;
E:1174;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2W83 1.93 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE ARF6 GTPASE IN COMPLEX WITH A SPECIFIC EFFECTOR, JIP4 HOMO SAPIENS GOLGI APPARATUS PROTEIN TRANSPORT ER-GOLGI TRANSPORT ARF GTPASE EFFECTOR MYRISTATE CYTOPLASM NUCLEOTIDE-BINDING ALTERNATIVE SPLICING GTP-BINDING PHOSPHOPROTEIN HETEROTETRAMER TRANSPORT COILED-COIL LIPOPROTEIN COILED COIL
Ref.: THE STRUCTURAL BASIS OF ARF EFFECTOR SPECIFICITY: THE CRYSTAL STRUCTURE OF ARF6 IN A COMPLEX WITH JIP4. EMBO J. V. 28 2835 2009
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 2W83 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 2W83 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 2W83 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GTP; Similar ligands found: 156
No: Ligand ECFP6 Tc MDL keys Tc
1 GTP 1 1
2 GP3 0.921053 0.973684
3 GDP 0.909091 1
4 GSP 0.853659 0.948718
5 GNH 0.82716 0.986667
6 G1R 0.819277 0.986667
7 GAV 0.811765 0.961039
8 9GM 0.809524 0.973684
9 GNP 0.809524 0.973684
10 GCP 0.797619 0.973684
11 5GP 0.797468 0.986486
12 G 0.797468 0.986486
13 GMV 0.764706 0.973684
14 G2R 0.764045 0.961039
15 G5P 0.755319 0.973684
16 GTG 0.752688 0.936709
17 G2P 0.747126 0.961039
18 G3A 0.744681 0.973684
19 GDD 0.741935 0.961039
20 GDC 0.741935 0.961039
21 GKE 0.741935 0.961039
22 0O2 0.736264 0.986486
23 GP2 0.729412 0.961039
24 6CK 0.726316 0.936709
25 Y9Z 0.723404 0.902439
26 GPG 0.717391 0.961039
27 GFB 0.715789 0.961039
28 GDR 0.715789 0.961039
29 GPD 0.704082 0.925
30 GKD 0.693878 0.961039
31 JB2 0.693878 0.961039
32 GDX 0.686869 0.973684
33 ALF 5GP 0.685393 0.888889
34 GH3 0.681319 0.973333
35 YGP 0.677083 0.901235
36 G3D 0.67033 0.986486
37 GDP AF3 0.659574 0.888889
38 ALF GDP 0.659574 0.888889
39 GDP ALF 0.659574 0.888889
40 DGT 0.659341 0.923077
41 GMP 0.658228 0.88
42 G4P 0.655914 0.986486
43 JB3 0.653846 0.948718
44 NGD 0.647619 0.961039
45 CAG 0.642202 0.880952
46 2MD 0.62963 0.891566
47 MGP 0.619565 0.961039
48 U2G 0.616822 0.936709
49 6G0 0.612903 0.961039
50 MGD 0.612613 0.891566
51 TPG 0.608696 0.840909
52 CG2 0.605505 0.936709
53 GDP 7MG 0.601942 0.911392
54 FEG 0.601852 0.879518
55 G G 0.598039 0.948052
56 ZGP 0.59633 0.869048
57 PGD 0.591304 0.925
58 MD1 0.591304 0.891566
59 3GP 0.590909 0.946667
60 GPX 0.581633 0.946667
61 DGI 0.580645 0.923077
62 IDP 0.576087 0.972973
63 DBG 0.567797 0.948718
64 2GP 0.555556 0.96
65 FE9 0.555556 0.776596
66 G4M 0.547619 0.880952
67 BGO 0.544643 0.924051
68 GCP G 0.543689 0.921053
69 ATP 0.537634 0.92
70 HEJ 0.537634 0.92
71 G1G 0.533898 0.925
72 AQP 0.531915 0.92
73 5FA 0.531915 0.92
74 A G 0.525862 0.935065
75 G A A A 0.525862 0.923077
76 U A G G 0.521368 0.935065
77 HFD 0.520833 0.873418
78 R5I 0.520408 0.946667
79 R7I 0.520408 0.946667
80 01G 0.518868 0.902439
81 P2G 0.510638 0.883117
82 ITT 0.510638 0.868421
83 AKW 0.504348 0.890244
84 GGM 0.504274 0.901235
85 G1R G1R 0.504065 0.924051
86 DGP 0.5 0.910256
87 PGD O 0.5 0.850575
88 MGO 0.5 0.864198
89 DG 0.5 0.910256
90 P1G 0.5 0.871795
91 GTA 0.495495 0.936709
92 PRT 0.490741 0.959459
93 B4P 0.489362 0.894737
94 AP5 0.489362 0.894737
95 IMP 0.489362 0.959459
96 G U 0.487179 0.9
97 7DT 0.484536 0.906667
98 GPC 0.479339 0.879518
99 G C 0.478992 0.9
100 BA3 0.478723 0.894737
101 ADP 0.473684 0.92
102 G2Q 0.471698 0.961039
103 6YZ 0.470588 0.896104
104 G7M 0.46875 0.948052
105 C1Z 0.462963 0.986486
106 25L 0.458716 0.907895
107 A2D 0.457447 0.894737
108 RGT 0.45045 0.909091
109 AGS 0.45 0.873418
110 SAP 0.45 0.873418
111 SGP 0.44898 0.82716
112 A4P 0.445378 0.869048
113 G G G RPC 0.442623 0.875
114 ANP 0.441176 0.896104
115 ACQ 0.441176 0.896104
116 8GT 0.441176 0.875
117 APC G U 0.44 0.886076
118 AT4 0.438776 0.884615
119 G U34 0.438017 0.888889
120 6AD 0.436893 0.841463
121 G G G C 0.433071 0.9125
122 UP5 0.432203 0.873418
123 PCG 0.431373 0.933333
124 C2E 0.431373 0.921053
125 35G 0.431373 0.933333
126 A G C C 0.429688 0.911392
127 T99 0.427184 0.884615
128 5GP 5GP 0.427184 0.883117
129 TAT 0.427184 0.884615
130 AR6 0.425743 0.894737
131 APR 0.425743 0.894737
132 7DD 0.424242 0.906667
133 AN2 0.424242 0.907895
134 DG DG 0.423423 0.865854
135 AD9 0.421569 0.896104
136 M33 0.42 0.883117
137 7D4 0.42 0.835443
138 UCG 0.419847 0.911392
139 HDV 0.419048 0.825
140 H6Y 0.419048 0.946667
141 G C C C 0.416667 0.924051
142 ACP 0.415842 0.896104
143 T5A 0.414634 0.802326
144 A1R 0.412844 0.839506
145 ADQ 0.412844 0.871795
146 MGQ 0.412844 0.935897
147 A3R 0.412844 0.839506
148 MGT 0.411215 0.823529
149 A G U 0.410072 0.888889
150 93A 0.41 0.833333
151 A22 0.407407 0.907895
152 CA0 0.405941 0.896104
153 ATF 0.40566 0.884615
154 AGO 0.404762 0.888889
155 MGV 0.401786 0.890244
156 CGP 0.4 0.86747
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2W83; Ligand: GTP; Similar sites found with APoc: 574
This union binding pocket(no: 1) in the query (biounit: 2w83.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 2GJ8 ALF GDP None
2 3KIF GDL None
3 1PTR PRB None
4 5XKT GNP 1.21212
5 3DC4 ADP 1.81818
6 1BO4 COA 1.81818
7 1KO8 6PG 1.81818
8 5LLB 6YZ 3.0303
9 4M7V NAP 3.0303
10 1NJF ADP 3.63636
11 1NJF AGS 3.63636
12 2BEK ATP 3.63636
13 4PVR ASP 3.8961
14 4QRH 0O2 3.8961
15 6AIC AMP 3.8961
16 1SQL GUN 4.10959
17 3ZFD ANP 4.24242
18 2IS6 ADP 4.24242
19 3DKP ADP 4.24242
20 1E2K TMC 4.24242
21 2QQ0 TMP 4.24242
22 2QQ0 ADP 4.24242
23 2QQ0 ANP 4.24242
24 2QQ0 THM 4.24242
25 4GOX A3P 4.24242
26 4WZ6 ATP 4.24242
27 2O0J ADP 4.24242
28 3QVV A3P 4.24242
29 1I0B PEL 4.24242
30 1RRC ADP 4.84848
31 1SVI GDP 4.84848
32 1XKV ATP 4.84848
33 2Q2Y ADP 4.84848
34 2Q2Y MKR 4.84848
35 5I34 GDP 4.84848
36 5ZB0 ADP 4.84848
37 5ZB0 TYD 4.84848
38 1TL2 NDG 4.84848
39 5SWI BMA 4.84848
40 1D5C GDP 5.19481
41 4LPS GDP 5.19481
42 5U32 GDP 5.19481
43 5LB3 ADP 5.19481
44 5Y6N ADP 5.19481
45 2IXE ATP 5.19481
46 3BOS CDP 5.19481
47 1JJV ATP 5.19481
48 2RI1 GLP 5.19481
49 2VWT PYR 5.19481
50 4PU6 ASP 5.34351
51 1OYY AGS 5.45455
52 4IOK XPO 5.45455
53 4IOK ADP 5.45455
54 4GBM A3P 5.45455
55 2FFQ GSP 6.06061
56 3KJI ADP 6.06061
57 4ZNL BEF ADP 6.06061
58 4WOP CTP 6.06061
59 1FNN ADP 6.06061
60 3QXC ATP 6.06061
61 1UKZ ADP 6.06061
62 6B8B ADP 6.06061
63 5NM7 GLY 6.06061
64 4ZG4 VO4 ADP 6.49351
65 5ZBR ANP 6.49351
66 1UJ2 ADP 6.49351
67 1UJ2 C5P 6.49351
68 1UH4 GLC GLC GLC GLC GLC 6.49351
69 1GXU 2HP 6.59341
70 4KFU ACP 6.60377
71 1YRB GDP 6.66667
72 4NCN GTP 6.66667
73 1JI0 ATP 6.66667
74 4IHQ ADP 6.66667
75 1DAK DPU 6.66667
76 1DAK ADP 6.66667
77 1S3G AP5 6.66667
78 4MKG AP5 6.66667
79 1AKY AP5 6.66667
80 2J5V PCA 6.66667
81 1P72 ADP 6.66667
82 5UIV ADP 6.66667
83 1G41 ADP 6.66667
84 4TMK T5A 6.66667
85 3BFX A3P 6.66667
86 3COB ADP 7.27273
87 3NHB ADP 7.27273
88 1SKQ GDP 7.79221
89 1BG2 ADP 7.79221
90 1D2E GDP 7.79221
91 2B8W ALF 5GP 7.79221
92 4R43 GDP 7.79221
93 2DPY ADP 7.79221
94 2FAH GDP 7.79221
95 1IN4 ADP 7.79221
96 1KYA XYD 7.79221
97 1D2N ANP 7.79221
98 4ZDJ UTP 7.79221
99 1SES AMP 7.79221
100 6ACS CIT 7.79221
101 3BER AMP 7.79221
102 2HK9 ATR 7.79221
103 1ZUI SKM 7.79221
104 3VGL BGC 7.79221
105 5L3V GDP 7.87879
106 2ZFI ADP 7.87879
107 4NU0 AP5 7.87879
108 4R2I ANP 7.87879
109 5X40 ACP 7.87879
110 5EXT ADP 7.87879
111 5DT6 GLU 7.87879
112 4QOS ADP 7.87879
113 3IUY AMP 7.87879
114 5HV7 RBL 7.87879
115 1FL2 FAD 7.87879
116 3KIH GDL 8.24742
117 4R98 GNH 8.48485
118 5GVR LMR 8.48485
119 5Z69 AGS 8.48485
120 1V6A TRE 8.48485
121 3W5J GDP 9.09091
122 1WF3 GNP 9.09091
123 1M7G AV2 9.09091
124 2RCN GDP 9.09091
125 1V8K ANP 9.09091
126 2WHX ADP 9.09091
127 4CVN ADP 9.09091
128 5BQ5 ADP BEF 9.09091
129 4FCW ADP 9.09091
130 4LJ9 ACP 9.09091
131 4BQS ADP 9.09091
132 4BQS K2Q 9.09091
133 3IIJ ADP 9.09091
134 2C9O ADP 9.09091
135 2D7D ADP 9.09091
136 2JLR ANP 9.09091
137 2YOH WMJ 9.09091
138 1M7G ADP 9.09091
139 4FRZ ADP 9.09091
140 1M7G ADX 9.09091
141 1IWE IMP 9.09091
142 1NY5 ADP 9.09091
143 4NZ6 DGL 9.09091
144 2X7I CIT 9.09091
145 3CV2 OXL 9.09091
146 2AWN ADP 9.69697
147 1F9V ADP 9.69697
148 1ZIN AP5 9.69697
149 3RC3 ANP 9.69697
150 1CR1 TTP 9.69697
151 1T8U UAP SGN IDS SGN 9.69697
152 4U00 ADP 10.303
153 5KUT GDP 10.303
154 5KSZ GCP 10.303
155 4Q1A 2XZ 10.303
156 4Q1A UDP 10.303
157 3VX3 ADP 10.303
158 5AOG IAC 10.303
159 3BD9 A3P 10.303
160 2QN6 GDP 10.3896
161 4RD0 GDP 10.3896
162 2WIC GNP 10.3896
163 1FP6 ADP 10.3896
164 4IEE AGS 10.3896
165 2XAU ADP 10.3896
166 3B7G ANP 10.3896
167 3AB4 THR 10.3896
168 3R7F CP 10.3896
169 6AR9 3L4 10.3896
170 3FJG 3PG 10.3896
171 1T5C ADP 10.9091
172 1VKJ A3P 10.9091
173 3FYH ADP 10.9091
174 2GDJ ANP 10.9091
175 1B0U ATP 11.0687
176 3TK1 GDP 11.5152
177 1IHU AF3 11.5152
178 1IHU ADP 11.5152
179 1NN5 2DT 11.5152
180 1NN5 ANP 11.5152
181 4LC1 GDP 11.6883
182 1YZQ GNP 11.6883
183 2VVG ADP 11.6883
184 1TQ4 GDP 11.6883
185 6DEF GCP 11.6883
186 4P4T GDP 11.6883
187 5TSH ANP 11.6883
188 5TSH ADP 11.6883
189 1LVK MNT BEF 11.6883
190 1SQ5 ADP 11.6883
191 1XX6 ADP 11.6883
192 1VHT BA3 11.6883
193 2CHG ANP 11.6883
194 2ZPA ADP 11.6883
195 3UIE ANP 11.6883
196 4NE2 SH2 11.6883
197 4NE2 ADP 11.6883
198 1QF9 C5P 11.6883
199 1QF9 ADP 11.6883
200 1QF9 ALF 11.6883
201 5H4S RAM 11.6883
202 1W5T ADP 11.6883
203 1W5T ANP 11.6883
204 5TIV A3P 11.6883
205 2QJY UQ2 11.6883
206 2F5X ASP 11.6883
207 5BYK A3P 11.6883
208 5BYK OAQ 11.6883
209 4TL6 ANP 11.6883
210 1FEC FAD 11.6883
211 2HT6 GDP 12.1212
212 2CJW GDP 12.1212
213 1A4R GNH 12.1212
214 1A4R GDP 12.1212
215 1GRN AF3 12.1212
216 1MKY GDP 12.1212
217 1GRN GDP 12.1212
218 2NGR GDP 12.1212
219 2NGR AF3 12.1212
220 5AK0 8V1 12.1212
221 1X1R GDP 12.7273
222 4D81 ADP 12.7273
223 4OI4 ATP 12.7273
224 1NST A3P 12.7273
225 1APZ ASP 12.963
226 3WXM GTP 12.987
227 1G7S GDP 12.987
228 3H4S ADP 12.987
229 1DAR GDP 12.987
230 1OXV ANP 12.987
231 3DZD ADP 12.987
232 2QEN ADP 12.987
233 1YTM ATP 12.987
234 3FVQ ATP 12.987
235 1OS1 PYR 12.987
236 1OS1 ATP 12.987
237 4QM7 GTP 12.987
238 1G6H ADP 12.987
239 5WRJ A3P 12.987
240 4YS0 ADP 12.987
241 1LVG ADP 13.3333
242 3FWY ADP 13.3333
243 1W4R TTP 13.3333
244 2ORV 4TA 13.3333
245 1G7C 5GP 13.9394
246 3DEF GDP 13.9394
247 4WZA ACP 13.9394
248 4WZA ADP 13.9394
249 2PL3 ADP 13.9394
250 3HU3 AGS 13.9394
251 2ZJ5 ADP 13.9394
252 5FG3 GDP 14.2857
253 1JJ7 ADP 14.2857
254 4HI0 GDP 14.2857
255 2D2F ADP 14.2857
256 2HF9 GSP 14.2857
257 1U0J ADP 14.2857
258 4KBF AMP 14.2857
259 3P4X ADP 14.2857
260 1R6B ADP 14.2857
261 5E5U MLI 14.2857
262 4DID GDP 14.4737
263 1H65 GDP 14.5455
264 1L2T ATP 15.1515
265 3PQC GDP 15.5844
266 3B5J 12D 15.5844
267 4NON GDP 15.5844
268 1X6V ADP 15.5844
269 4XTR ATP 15.5844
270 4XVU ATP 15.5844
271 3BFV ADP 15.5844
272 3ZS9 ADP ALF 15.5844
273 4X8O AP5 15.5844
274 2WOJ ADP ALF 15.5844
275 1Z6T ADP 15.5844
276 4XTR ADP 15.5844
277 4BFW ZVW 15.5844
278 2QG6 NMN 15.5844
279 3QKT ANP 15.5844
280 2PEZ DAT 15.5844
281 2PEZ GGZ 15.5844
282 3ITJ CIT 15.5844
283 1F2U ATP 15.5844
284 3N29 GOL 15.5844
285 2OFW ADX 15.5844
286 3H86 AP5 15.625
287 6G14 G4P 15.7576
288 3QF7 ANP 16
289 3EC1 GDP 16.8831
290 4B47 GDP 16.8831
291 1W7J ADP BEF 16.8831
292 4TVD BGC 16.8831
293 1LK7 DER 16.8831
294 3Q85 GNP 16.9697
295 1PUJ GNP 16.9697
296 3RLF ANP 16.9697
297 2CDN ADP 17.5758
298 2IYL GDP 18.1818
299 1RJ9 GCP 18.1818
300 3TBK ANP 18.1818
301 3FB4 AP5 18.1818
302 2RGX AP5 18.1818
303 3TMK T5A 18.1818
304 1P4V GLY 18.1818
305 4HSE ADP 18.1818
306 3LL4 2FP 18.1818
307 2B4B COA 18.1818
308 2WKQ GTP 18.7879
309 2J0V GDP 18.7879
310 2BIF ANP 18.7879
311 2BIF SIN 18.7879
312 4B16 NAG 18.7879
313 4U5X GNP 19.3939
314 6D5E GNP 19.4805
315 6BVJ GNP 19.4805
316 2C5L GTP 19.4805
317 6D5H GNP 19.4805
318 6D5J GNP 19.4805
319 6BVK GNP 19.4805
320 6D5G GNP 19.4805
321 5WLB GNP 19.4805
322 1LFD GNP 19.4805
323 1NVV GNP 19.4805
324 2UZI GTP 19.4805
325 6BVL GNP 19.4805
326 6D5L GNP 19.4805
327 6BVI GNP 19.4805
328 6D55 GNP 19.4805
329 6D56 GNP 19.4805
330 6D59 GNP 19.4805
331 6BVM GNP 19.4805
332 6D5M GNP 19.4805
333 6D5V GNP 19.4805
334 3DDC GNP 19.4805
335 1CLU DBG 19.4805
336 3KUD GDP 19.4805
337 3B9Q MLI 19.4805
338 4K81 GTP 19.4805
339 2OG2 MLI 19.4805
340 1WQ1 GDP 19.4805
341 3A4M ADP 19.4805
342 5L3R GCP 19.4805
343 1ION ADP 19.4805
344 1WQ1 AF3 19.4805
345 1G3Q ADP 19.4805
346 2KIN ADP 20
347 4YMU ATP 20
348 2C77 GNP 20.6061
349 2C78 GNP 20.6061
350 4RLQ 3SK 20.6061
351 2XT3 ADP 20.7792
352 4ITR GDP 20.7792
353 1QF5 RPL 20.7792
354 1QF5 GDP 20.7792
355 1W0J ADP 20.7792
356 2VB6 ADP BEF 20.7792
357 2CK3 ANP 20.7792
358 4IDN GNP 20.7792
359 4PFO ADP 20.7792
360 2FSH ANP 20.7792
361 2V7Q ATP 20.7792
362 4TTQ ATP 20.7792
363 1W0J ADP BEF 20.7792
364 2NCD ADP 20.7792
365 1NHX FTB 20.7792
366 2CK3 ADP 20.7792
367 1NHX PEP 20.7792
368 2GMV UN8 20.7792
369 2V7Q ADP 20.7792
370 2GMV PEP 20.7792
371 5KSP GDP 21.8182
372 1G8S MET 21.8182
373 1LOJ URI 21.8391
374 1LOJ U 21.8391
375 1D8T GDP 22.0779
376 2BVN GNP 22.0779
377 2HCJ GDP 22.0779
378 4AG5 ADP 22.0779
379 5HCN GCP 22.0779
380 4A4Z ANP 22.0779
381 6AU6 GDP 23.0303
382 2XTZ GSP 23.0303
383 2ZEJ GDP 23.0303
384 6CS8 F9Y 23.0303
385 2CE7 ADP 23.3766
386 5MZN ADP 23.3766
387 1GWN GTP 23.6364
388 1M7B GTP 23.6364
389 1KMQ GNP 24.2424
390 3A1S GDP 24.4186
391 3E70 GDP 24.6753
392 5L3S GNP 24.6753
393 5L3W GDP 24.6753
394 5L3S G 24.6753
395 1XP8 AGS 24.6753
396 4HAT GNP 24.8485
397 5UWP GNP 24.8485
398 5UWU GNP 24.8485
399 5UWQ GNP 24.8485
400 5UWT GNP 24.8485
401 5UWH GNP 24.8485
402 6CIT GNP 24.8485
403 5UWO GNP 24.8485
404 5DHF GNP 24.8485
405 5UWS GNP 24.8485
406 3CH5 GDP 24.8485
407 3GJ3 GDP 24.8485
408 5BXQ GDP 24.8485
409 3GJ0 GDP 24.8485
410 5UWW GNP 24.8485
411 5UWI GNP 24.8485
412 5UWR GNP 24.8485
413 5UWJ GNP 24.8485
414 5DIF GNP 24.8485
415 1IBR GNP 24.8485
416 5DI9 GNP 24.8485
417 5UQW GDP 25.3968
418 3GJ5 GDP 25.4545
419 3GJ7 GDP 25.4545
420 3GJ4 GDP 25.4545
421 3REF GDP 25.4545
422 3GJ8 GDP 25.4545
423 1K6M AGS 25.4545
424 5TB5 GDP 25.9459
425 5TAR GDP 25.9459
426 5M04 GDP 25.974
427 5BN3 ADP 25.974
428 4PX9 ADP 25.974
429 1SVM ATP 25.974
430 3Q72 GNP 26.0606
431 4H1V GNP 26.0606
432 1NRJ GTP 26.6055
433 1TAD GDP 26.6667
434 1TAD ALF 26.6667
435 5YT0 GDP 27.2727
436 3T12 GDP ALF 27.2727
437 1GOJ ADP 27.2727
438 3T1O GDP 27.2727
439 1GOT GDP 27.2727
440 1KK8 BEF ADP 27.2727
441 1XMV ADP 27.2727
442 1B7T ADP 27.2727
443 3KTA AP5 27.2727
444 1P9B GDP 27.2727
445 1P9B HDA 27.2727
446 1KAO GDP 27.5449
447 6FA4 GNP 27.7457
448 5O2T GSP 28.4024
449 1FQJ ALF 28.4848
450 1FQK ALF 28.4848
451 1FQJ GDP 28.4848
452 1FQK GDP 28.4848
453 6BSX GDP 28.4848
454 3T5G GDP 28.4848
455 6BSX E7S 28.4848
456 2W58 ADP 28.5714
457 5I0H ADP BEF 28.5714
458 4UXH T5A 28.5714
459 1GPE FAD 28.5714
460 1BH2 GSP 29.0909
461 4HDO GNP 29.0909
462 1GUA GNP 29.0909
463 1U8Z GDP 29.0909
464 2OM2 GDP 29.0909
465 1Y3A GDP 29.0909
466 6CRK GDP 29.0909
467 5KDO GDP 29.0909
468 1GP2 GDP 29.0909
469 4DCT GDP 29.697
470 2ODE ALF GDP 29.697
471 1SVK ALF GDP 29.697
472 1CS4 GSP 29.8701
473 3MD0 GDP 29.8701
474 3ZQ6 ADP ALF 29.8701
475 2GK6 ADP 29.8701
476 1E96 GTP 30.303
477 5OCG GNP 30.303
478 2W2X GSP 30.9091
479 2FJU GSP 30.9091
480 1MH1 GNP 30.9091
481 1HE1 GDP 30.9091
482 1HE1 AF3 30.9091
483 1G4U GDP 30.9091
484 1G4U AF3 30.9091
485 2XTN GTP 30.9091
486 4MKF AP5 31.1688
487 1XEX ATP 31.1688
488 2WJG GDP 31.5152
489 1VG1 GDP 31.5152
490 1VG9 GDP 31.5152
491 1VG8 GNP 31.5152
492 1VG0 GDP 31.5152
493 3SBD GNP 31.5152
494 2WJH FLC 31.5152
495 2WJH GDP 31.5152
496 1Z0F GDP 31.5152
497 1CXZ GSP 32.1212
498 1S8F GDP 32.1212
499 2GCO GNP 32.1212
500 4D0N GDP 32.1212
501 1DS6 GDP 32.1212
502 1TX4 ALF GDP 32.1212
503 5IRC GDP 32.1212
504 1OW3 GDP 32.1212
505 5HPY GDP 32.1212
506 2GCN GDP 32.1212
507 2A5J GDP 32.1212
508 5Z2M GTP 32.1212
509 3CX8 GSP 32.4675
510 2Y65 ADP 32.4675
511 6C90 ADP 32.4675
512 5N69 ADP 32.4675
513 2BME GNP 32.7273
514 2D7C GTP 32.7273
515 4C4P GNP 32.7273
516 3RWO GDP 32.7273
517 1OIV GDP 32.7273
518 2F9L GDP 32.7273
519 1Z0K GTP 33.3333
520 2HV8 GTP 33.3333
521 1OIX GDP 33.3333
522 1Z2A GDP 33.3333
523 1G16 GDP 33.3333
524 2ZR9 DTP 33.7662
525 6B4K ANP 33.7662
526 1WA5 GTP 33.9394
527 5CK5 GDP 33.9394
528 2QZ4 ADP 33.9394
529 1EK0 GNP 34.5455
530 3AB3 GDP 34.5455
531 1RYH GNP 34.5455
532 1Z08 GNP 34.5455
533 3M1I GTP 35.0649
534 1G6O ADP 35.0649
535 1Z83 AP5 35.0649
536 1OFH ADP 35.0649
537 2A9K GDP 35.7576
538 5UPK GNP 36.3636
539 1TU3 GNP 36.3636
540 1R2Q GNP 36.3636
541 1KY3 GDP 36.3636
542 1NF3 GNP 36.3636
543 1ZC3 GNP 36.3636
544 3ZIA ATP 36.3636
545 3ZIA ADP 36.3636
546 2GKS ADP 36.3636
547 5HR5 ADP 36.3636
548 1YVD GNP 36.9697
549 3BC1 GNP 36.9697
550 3MJH GTP 36.9697
551 1YZN GNP 36.9697
552 2BCG GDP 36.9697
553 5O74 GDP 37.5758
554 1Z0J GTP 37.5758
555 3RAB GNP 37.5758
556 1KK1 GNP 37.6623
557 1I4D GDP 37.6623
558 1YQT ADP 37.6623
559 5ZXD ATP 37.6623
560 5YV5 ADP 37.6623
561 1QHH ATP 37.6623
562 1QHG ATP 37.6623
563 3QBT GNP 38.1818
564 2FH5 GTP 38.7879
565 1F5N GNP 38.961
566 2G77 GDP 39.3939
567 1Z06 GNP 39.3939
568 2G77 AF3 39.3939
569 4PJ3 ANP 40.2597
570 5XC5 GTP 40.6061
571 1Z0A GDP 41.2121
572 2QTV GNP 46.6667
573 1M2O GNP 46.6667
574 1F6B GDP 48.4848
Pocket No.: 2; Query (leader) PDB : 2W83; Ligand: GTP; Similar sites found with APoc: 25
This union binding pocket(no: 2) in the query (biounit: 2w83.bio1) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 5AHO TLA None
2 4M7V RAR 3.0303
3 5YLF BGC 3.63636
4 1CM0 COA 3.63636
5 3B2Q AES 3.8961
6 3LN9 FLC 5.03597
7 2ZE7 DST 5.19481
8 3TW1 AHN 5.19481
9 1M0S CIT 5.45455
10 4WOH 4NP 6.66667
11 3L6C MLI 6.66667
12 1O8B ABF 9.09091
13 2JBH 5GP 9.69697
14 4JBL MET 9.69697
15 4CR6 MAN 10.3896
16 2JAQ DCP 11.6883
17 1CBK ROI 11.6883
18 4LHD GLY 11.6883
19 1OE0 TTP 13.9394
20 2Z48 NGA 16.9697
21 2Z49 AMG 16.9697
22 1WUU GLA 22.0779
23 3KC1 2T6 23.3766
24 1ZOY UQ1 31.5152
25 5JBX MLI 35.0649
Pocket No.: 3; Query (leader) PDB : 2W83; Ligand: GTP; Similar sites found with APoc: 13
This union binding pocket(no: 3) in the query (biounit: 2w83.bio1) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 1LNX URI None
2 4NFE BEN 3.63636
3 2WGV CIT 5.45455
4 2F6U CIT 6.06061
5 6DZN AE3 7.79221
6 3GUZ PAF 7.79221
7 4TQK NAG 9.09091
8 1T8U A3P 9.69697
9 5WRI A3P 12.987
10 1UKG MMA 16.8831
11 2Z48 A2G 16.9697
12 1GPJ CIT 22.0779
13 4IV9 FAD 27.2727
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