-->
Receptor
PDB id Resolution Class Description Source Keywords
2W2X 2.3 Å EC: 3.1.4.11 COMPLEX OF RAC2 AND PLCG2 SPPH DOMAIN HOMO SAPIENS HYDROLASE PHOSPHOLIPASE C PHOSPHOINOSITIDES RHO GTPASES RAC SH2 DOMAIN SH3 DOMAIN SIGNALING PROTEIN/HYDROLASE
Ref.: STRUCTURAL INSIGHTS INTO FORMATION OF AN ACTIVE SIGNALING COMPLEX BETWEEN RAC AND PHOSPHOLIPASE C GAMMA 2. MOL.CELL V. 34 223 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GSP A:1178;
B:1178;
Valid;
Valid;
none;
none;
submit data
539.246 C10 H16 N5 O13 P3 S c1nc2...
MG A:1179;
B:1179;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2W2X 2.3 Å EC: 3.1.4.11 COMPLEX OF RAC2 AND PLCG2 SPPH DOMAIN HOMO SAPIENS HYDROLASE PHOSPHOLIPASE C PHOSPHOINOSITIDES RHO GTPASES RAC SH2 DOMAIN SH3 DOMAIN SIGNALING PROTEIN/HYDROLASE
Ref.: STRUCTURAL INSIGHTS INTO FORMATION OF AN ACTIVE SIGNALING COMPLEX BETWEEN RAC AND PHOSPHOLIPASE C GAMMA 2. MOL.CELL V. 34 223 2009
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 2W2X - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 2W2X - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 2W2X - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GSP; Similar ligands found: 139
No: Ligand ECFP6 Tc MDL keys Tc
1 GSP 1 1
2 GP3 0.897436 0.925
3 GTP 0.853659 0.948718
4 GNH 0.829268 0.936709
5 GDP 0.817073 0.948718
6 G1R 0.8 0.936709
7 GCP 0.77907 0.925
8 GNP 0.770115 0.925
9 9GM 0.770115 0.925
10 GMV 0.767442 0.925
11 G 0.756098 0.935897
12 5GP 0.756098 0.935897
13 G2R 0.747253 0.91358
14 GDD 0.744681 0.91358
15 GDC 0.744681 0.91358
16 GKE 0.744681 0.91358
17 GPG 0.73913 0.91358
18 GTG 0.736842 0.891566
19 G3A 0.729167 0.925
20 G5P 0.721649 0.925
21 GDR 0.71875 0.91358
22 GFB 0.71875 0.91358
23 GAV 0.714286 0.987179
24 GP2 0.712644 0.91358
25 6CK 0.71134 0.891566
26 Y9Z 0.708333 0.860465
27 JB2 0.69697 0.91358
28 GKD 0.69697 0.91358
29 G2P 0.692308 0.91358
30 GDX 0.69 0.925
31 GPD 0.69 0.880952
32 ALF 5GP 0.67033 0.847059
33 0O2 0.666667 0.935897
34 YGP 0.663265 0.858824
35 JB3 0.657143 0.902439
36 GDP ALF 0.645833 0.847059
37 GDP AF3 0.645833 0.847059
38 ALF GDP 0.645833 0.847059
39 GMP 0.641975 0.835443
40 G3D 0.638298 0.935897
41 NGD 0.635514 0.91358
42 2MD 0.633027 0.894118
43 CAG 0.630631 0.840909
44 G4P 0.625 0.935897
45 FEG 0.62037 0.83908
46 U2G 0.62037 0.891566
47 G G 0.617647 0.901235
48 MGD 0.616071 0.894118
49 ZGP 0.614679 0.872093
50 CG2 0.609091 0.891566
51 TPG 0.598291 0.804348
52 3GP 0.595506 0.898734
53 GDP 7MG 0.590476 0.86747
54 GH3 0.581633 0.924051
55 PGD 0.581197 0.926829
56 MD1 0.581197 0.894118
57 2GP 0.577778 0.911392
58 GCP G 0.563107 0.875
59 DGT 0.561224 0.878049
60 DBG 0.558333 0.902439
61 G1G 0.550847 0.880952
62 AGS 0.547368 0.924051
63 SAP 0.547368 0.924051
64 FE9 0.546219 0.8
65 A G 0.543103 0.888889
66 G4M 0.539062 0.840909
67 U A G G 0.538462 0.888889
68 G A A A 0.529915 0.878049
69 MGP 0.525253 0.91358
70 GPX 0.524272 0.898734
71 BGO 0.521739 0.879518
72 DGI 0.520408 0.878049
73 6G0 0.52 0.91358
74 IDP 0.515464 0.923077
75 R7I 0.51 0.898734
76 R5I 0.51 0.898734
77 GGM 0.508475 0.858824
78 G1R G1R 0.508065 0.879518
79 PGD O 0.504 0.875
80 AKW 0.495726 0.915663
81 G U 0.491525 0.857143
82 GTA 0.486726 0.891566
83 P2G 0.484536 0.839506
84 GPC 0.483607 0.83908
85 G C 0.483333 0.857143
86 P1G 0.474747 0.829268
87 DG 0.474227 0.865854
88 DGP 0.474227 0.865854
89 BA3 0.46875 0.85
90 IMP 0.463918 0.910256
91 B4P 0.463918 0.85
92 AP5 0.463918 0.85
93 G2Q 0.462963 0.91358
94 G G G RPC 0.459016 0.833333
95 APC G U 0.456 0.843373
96 ATP 0.45 0.873418
97 HEJ 0.45 0.873418
98 G G G C 0.448819 0.869048
99 A2D 0.447917 0.85
100 5FA 0.445545 0.873418
101 AQP 0.445545 0.873418
102 A G C C 0.445312 0.86747
103 G7M 0.444444 0.901235
104 G U34 0.442623 0.847059
105 01G 0.442478 0.860465
106 ITT 0.44 0.825
107 SGP 0.44 0.876543
108 HFD 0.436893 0.831325
109 G C C C 0.431818 0.879518
110 AT4 0.43 0.911392
111 AN2 0.43 0.8625
112 DG DG 0.428571 0.825581
113 A4P 0.42623 0.829545
114 UCG 0.424242 0.86747
115 PCG 0.423077 0.886076
116 C2E 0.423077 0.875
117 35G 0.423077 0.886076
118 MGO 0.420561 0.823529
119 ADP 0.42 0.873418
120 ANP 0.419048 0.851852
121 5GP 5GP 0.419048 0.839506
122 ADQ 0.418182 0.829268
123 7DT 0.417476 0.860759
124 AR6 0.417476 0.85
125 APR 0.417476 0.85
126 PRT 0.417391 0.910256
127 C1Z 0.415929 0.935897
128 A G U 0.414286 0.847059
129 AD9 0.413462 0.851852
130 UP5 0.413223 0.831325
131 A22 0.412844 0.8625
132 25L 0.412281 0.8625
133 M33 0.411765 0.839506
134 JBT 0.410405 0.783505
135 ACP 0.407767 0.851852
136 6YZ 0.407407 0.851852
137 ACQ 0.40566 0.851852
138 A1R 0.405405 0.8
139 A G U U 0.4 0.847059
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2W2X; Ligand: GSP; Similar sites found with APoc: 621
This union binding pocket(no: 1) in the query (biounit: 2w2x.bio2) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 4E03 ADP None
2 2IL4 COA None
3 2OZE AGS 2.16216
4 1G3Q ADP 2.16216
5 2QQ0 ANP 2.71739
6 2QQ0 ADP 2.71739
7 2QQ0 TMP 2.71739
8 2QQ0 THM 2.71739
9 4QM7 GTP 2.92398
10 1P9B GDP 3.16742
11 3MD0 GDP 3.22581
12 4WOP CTP 3.22581
13 1ME8 RVP 3.22581
14 1XP8 AGS 3.22581
15 5WRJ A3P 3.24324
16 5MVR ADP 3.7037
17 2DPY ADP 3.78378
18 6B4K ANP 3.78378
19 2XAU ADP 3.78378
20 1NN5 2DT 3.78378
21 1NN5 ANP 3.78378
22 2ORV 4TA 3.78378
23 3B8I OXL 3.78378
24 1RRC ADP 3.78378
25 1V8K ANP 4.03226
26 1SVI GDP 4.03226
27 1LVG ADP 4.03226
28 4DDY DN6 4.03226
29 2BEK ATP 4.03226
30 1AKY AP5 4.03226
31 1L2T ATP 4.03226
32 2X7I CIT 4.03226
33 4RZ3 ADP 4.03226
34 2VOH CIT 4.03226
35 6AIC AMP 4.03226
36 5GOE GDP 4.32432
37 5TSH ANP 4.32432
38 5TSH ADP 4.32432
39 4LYA ATP 4.32432
40 1DAK DPU 4.32432
41 1DAK ADP 4.32432
42 4JLV ADP 4.32432
43 3FVQ ATP 4.32432
44 1NJF ADP 4.32432
45 1UJ2 ADP 4.32432
46 1UJ2 C5P 4.32432
47 1NJF AGS 4.32432
48 4O48 ASP 4.32432
49 1VBO MAN MAN MAN 4.32432
50 2WJH GDP 4.81928
51 2WJH FLC 4.81928
52 1M7G AV2 4.83871
53 5XDR ADP 4.83871
54 1M7G ADX 4.83871
55 1M7G ADP 4.83871
56 2QZ4 ADP 4.83871
57 1APZ ASP 4.83871
58 2O0J ADP 4.83871
59 2ZTS ADP 4.83871
60 4X1Z FUC GAL NDG 4.83871
61 2WJG GDP 4.86486
62 1OXV ANP 4.86486
63 2D2F ADP 4.86486
64 5VGR GDP 4.86486
65 3IO3 ADP 4.86486
66 2CBZ ATP 4.86486
67 2XZ9 PYR 4.86486
68 1W4R TTP 5.12821
69 2VVG ADP 5.40541
70 4U00 ADP 5.40541
71 1XX6 ADP 5.40541
72 3EZ2 ADP 5.40541
73 2FAH GDP 5.40541
74 5J1J ANP 5.40541
75 3FB4 AP5 5.40541
76 1R6B ADP 5.40541
77 4WZ6 ATP 5.40541
78 3W5J GDP 5.64516
79 2ZFI ADP 5.64516
80 1G7S GDP 5.64516
81 4YDS ATP 5.64516
82 1JI0 ATP 5.64516
83 3T1O GDP 5.64516
84 3EWA ANP 5.64516
85 1G6O ADP 5.64516
86 5MZN ADP 5.64516
87 4FCW ADP 5.64516
88 6CS8 F9Y 5.64516
89 4LJ9 ACP 5.64516
90 1OYY AGS 5.64516
91 1KO8 6PG 5.64516
92 5Z69 AGS 5.64516
93 6B8B ADP 5.64516
94 1ION ADP 5.64516
95 4AG9 COA 5.64516
96 4NZ6 DGL 5.64516
97 1GPJ CIT 5.69307
98 4NON GDP 5.94595
99 3TK1 GDP 5.94595
100 1IWE IMP 5.94595
101 1SQ5 ADP 5.94595
102 2QEN ADP 5.94595
103 1U0J ADP 5.94595
104 4NE2 SH2 5.94595
105 4NE2 ADP 5.94595
106 4NU0 AP5 5.94595
107 5G3Y ADP 5.94595
108 1QHG ATP 5.94595
109 1U1I NAD 5.94595
110 1UPT GTP 6.45161
111 4M9Q GNP 6.45161
112 4LC1 GDP 6.45161
113 2AWN ADP 6.45161
114 2PZE ATP 6.45161
115 4IHQ ADP 6.45161
116 5GVR LMR 6.45161
117 1ZUI SKM 6.45161
118 4XGU ADP 6.45161
119 4PFO ADP 6.45161
120 5LTJ BEF 6.45161
121 3KTA AP5 6.45161
122 2ZPA ADP 6.45161
123 4X8O AP5 6.45161
124 1F9V ADP 6.45161
125 5G41 AP5 6.45161
126 1D2N ANP 6.45161
127 5LTJ ADP 6.45161
128 1NHX FTB 6.45161
129 1NHX PEP 6.45161
130 2GMV UN8 6.45161
131 3QIN P1Y 6.45161
132 4RLQ 3SK 6.45161
133 2GMV PEP 6.45161
134 2RCN GDP 6.48649
135 5XKT GNP 6.48649
136 1RJ9 GCP 6.48649
137 3KJI ADP 6.48649
138 5I34 GDP 6.48649
139 3IUY AMP 6.48649
140 4QRH 0O2 6.48649
141 5E58 CPZ 6.48649
142 5W76 GDP 6.75325
143 1G8S MET 6.95652
144 1HTW ADP 6.96203
145 5FTB ANP 7.02703
146 5BQ5 ADP BEF 7.02703
147 3DC4 ADP 7.02703
148 4V03 ADP 7.02703
149 5FHD ADP ALF 7.02703
150 1OFH ADP 7.02703
151 4ZNL BEF ADP 7.02703
152 5H4S RAM 7.02703
153 4UXH T5A 7.06522
154 1WDT GTP 7.25806
155 2GJ8 ALF GDP 7.25806
156 3WYA GDP 7.25806
157 3Q9L ATP 7.25806
158 3DZD ADP 7.25806
159 5Y6N ADP 7.25806
160 4KBF AMP 7.25806
161 4HSE ADP 7.25806
162 1ZIN AP5 7.25806
163 3BOS CDP 7.25806
164 4YMU ATP 7.25806
165 3BFV ADP 7.25806
166 4IOK XPO 7.25806
167 4IOK ADP 7.25806
168 2YOH WMJ 7.25806
169 3BER AMP 7.25806
170 5HWK BEZ 7.25806
171 4GBM A3P 7.25806
172 5TQZ GLC 7.25806
173 4Y4V DAL 7.37463
174 3U6B GDP 7.56757
175 2BVN GNP 7.56757
176 4P3Y GDP 7.56757
177 3U6K GDP 7.56757
178 1D8T GDP 7.56757
179 1PUJ GNP 7.56757
180 6G14 G4P 7.56757
181 3H4S ADP 7.56757
182 4PC3 GDP 7.56757
183 5JBQ GDP 7.56757
184 4G5G GDP 7.56757
185 4HI0 GDP 7.56757
186 4P4T GDP 7.56757
187 4OHY ANP 7.56757
188 4FRZ ADP 7.56757
189 1G41 ADP 7.56757
190 1VKJ A3P 7.56757
191 5AHO TLA 7.56757
192 4IEE AGS 7.56757
193 2HCJ GDP 7.76119
194 2FH5 GTP 8.06452
195 5W7Q GDP 8.06452
196 5BN3 ADP 8.06452
197 3FWY ADP 8.06452
198 2GK6 ADP 8.06452
199 2D7D ADP 8.06452
200 4BFW ZVW 8.06452
201 2C9O ADP 8.06452
202 1Y63 ADP 8.06452
203 5H67 ATP 8.06452
204 5TIV A3P 8.06452
205 5V4R MGT 8.06452
206 2WIC GNP 8.10811
207 3B5J 12D 8.10811
208 3FKQ ATP 8.10811
209 2PL3 ADP 8.10811
210 5K5Z ANP 8.10811
211 3CV2 OXL 8.10811
212 2O66 FLC 8.14815
213 5CIC 51R 8.33333
214 4KFU ACP 8.64865
215 4KVA GTP 8.64865
216 2OBM ADP 8.64865
217 3E70 GDP 8.64865
218 4Q1A UDP 8.64865
219 4Q1A 2XZ 8.64865
220 4PX9 ADP 8.64865
221 4R2I ANP 8.64865
222 1E2K TMC 8.64865
223 1NX9 AIC 8.64865
224 3T12 GDP ALF 8.82353
225 2W58 ADP 8.87097
226 2XTZ GSP 8.87097
227 1DAR GDP 8.87097
228 4WZA ADP 8.87097
229 4WZA ACP 8.87097
230 2HF9 GSP 8.87097
231 1W7J ADP BEF 8.87097
232 1FP6 ADP 8.87097
233 5L3W GDP 8.87097
234 1FNN ADP 8.87097
235 1YTM ATP 8.87097
236 5EXT ADP 8.87097
237 1IN4 ADP 8.87097
238 5M7P ADP 8.87097
239 3QXC ATP 8.87097
240 4BJH PAL 8.87097
241 3BFX A3P 8.87097
242 2C78 GNP 9.18919
243 2C77 GNP 9.18919
244 3COB ADP 9.18919
245 1JJ7 ADP 9.18919
246 4OI4 ATP 9.18919
247 3R7F CP 9.18919
248 1IHU AF3 9.18919
249 2IXE ATP 9.18919
250 3VX3 ADP 9.18919
251 1IHU ADP 9.18919
252 3IIJ ADP 9.44444
253 1KK1 GNP 9.67742
254 3CX8 GSP 9.67742
255 5U32 GDP 9.67742
256 6A20 ADP 9.67742
257 3AB3 GDP 9.67742
258 5ZBR ANP 9.67742
259 1ZCB GDP 9.67742
260 4R43 GDP 9.67742
261 1XMV ADP 9.67742
262 2CE7 ADP 9.67742
263 1H65 GDP 9.67742
264 3DKP ADP 9.67742
265 2FSH ANP 9.67742
266 1S3G AP5 9.67742
267 2GKS ADP 9.67742
268 1XPJ TLA 9.67742
269 2GWH A3P 9.67742
270 4TL6 ANP 9.67742
271 1ITU CIL 9.67742
272 5HCN GCP 9.72973
273 1LVK MNT BEF 9.72973
274 4YJ1 ADP 9.72973
275 4A4Z ANP 9.72973
276 4YS0 ADP 9.72973
277 2IS6 ADP 9.72973
278 1O8B ABF 9.72973
279 5J1S ATP 9.7561
280 4J0Q GDP 10.2703
281 4R98 GNH 10.2703
282 2B8W ALF 5GP 10.2703
283 1F5N GNP 10.2703
284 1VHT BA3 10.2703
285 3H86 AP5 10.2703
286 5FG3 GDP 10.4839
287 3A1S GDP 10.4839
288 3ZFD ANP 10.4839
289 1D2E GDP 10.4839
290 5LB3 ADP 10.4839
291 3DEF GDP 10.4839
292 5ZXD ATP 10.4839
293 2CDN ADP 10.4839
294 3TBK ANP 10.4839
295 1QF5 GDP 10.4839
296 1QF5 RPL 10.4839
297 5N69 ADP 10.4839
298 1SVM ATP 10.4839
299 2FNA ADP 10.4839
300 3NHB ADP 10.4839
301 1G6H ADP 10.4839
302 3CNL GNP 10.8108
303 2ZR9 DTP 10.8108
304 2ZE7 AMP 10.8108
305 2ZE7 DST 10.8108
306 1NRJ GTP 11.0092
307 5W75 GDP 11.2903
308 4ZKD GDP 11.2903
309 2OG2 MLI 11.2903
310 6DEF GCP 11.2903
311 2IYL GDP 11.2903
312 1KK8 BEF ADP 11.2903
313 1B7T ADP 11.2903
314 3B7G ANP 11.2903
315 1Z6T ADP 11.2903
316 4IDN GNP 11.2903
317 5H68 AGS 11.2903
318 1P72 ADP 11.2903
319 5IRN ADP 11.2903
320 1NY5 ADP 11.2903
321 2QG6 NMN 11.2903
322 4WEI GLC GAL 11.2903
323 1UKZ ADP 11.2903
324 1QHH ATP 11.3043
325 5H7K GDP 11.3514
326 4PPF FLC 11.3514
327 2Y65 ADP 11.3514
328 3A4M ADP 11.3514
329 5AK0 8V1 11.3514
330 5ZB0 TYD 11.3514
331 5ZB0 ADP 11.3514
332 3JUC PCA 11.7647
333 1YRB GDP 11.8919
334 5HR5 ADP 11.8919
335 3RC3 ANP 11.8919
336 6AU6 GDP 12.0968
337 1R0X ATP 12.0968
338 3ZQ6 ADP ALF 12.0968
339 2Q2Y ADP 12.0968
340 2Q2Y MKR 12.0968
341 1W5T ADP 12.0968
342 1W5T ANP 12.0968
343 5CK5 GDP 12.4324
344 4LPS GDP 12.4324
345 2CK3 ANP 12.4324
346 1W0J ADP 12.4324
347 2V7Q ATP 12.4324
348 2OFW ADX 12.4324
349 1W0J ADP BEF 12.4324
350 1X6V ADP 12.4324
351 2ZJ5 ADP 12.4324
352 2V7Q ADP 12.4324
353 2CK3 ADP 12.4324
354 1BO4 COA 12.5
355 2PEZ GGZ 12.8492
356 2PEZ DAT 12.8492
357 5EE5 GTP 12.8655
358 4B47 GDP 12.9032
359 2WHX ADP 12.9032
360 3B9Q MLI 12.9032
361 3T34 GDP 12.9032
362 5IFS ADP 12.9032
363 4D81 ADP 12.9032
364 3HU3 AGS 12.9032
365 2JLR ANP 12.9032
366 4GOX A3P 12.9032
367 1TQ4 GDP 12.973
368 4ZDJ UTP 12.973
369 1Z83 AP5 12.973
370 6C90 ADP 13.4615
371 5IRR GSP 13.5135
372 5L3S GNP 13.5135
373 5L3V GDP 13.5135
374 5L3S G 13.5135
375 3QKT ANP 13.5135
376 4Z0G 5GP 13.5135
377 4Z87 5GP 13.5135
378 4TTQ ATP 13.7097
379 5NM7 GLY 13.7097
380 6FAA ADP 13.7097
381 4AF0 IMP 13.7097
382 2X77 GDP 13.7566
383 5M04 GDP 14.0541
384 1K6M AGS 14.0541
385 1CS4 GSP 14.5161
386 5H7J GCP 14.5161
387 3RLF ANP 14.5161
388 5E5U MLI 14.5161
389 1T5C ADP 14.5161
390 2ODE ALF GDP 14.5946
391 1T8U UAP SGN IDS SGN 14.5946
392 2W8Q SIN 14.5946
393 2QTV GNP 15.1351
394 1M2O GNP 15.1351
395 3WXM GTP 15.3226
396 3VMF GTP 15.3226
397 1GOJ ADP 15.3226
398 5WC2 ADP 15.3226
399 2RGX AP5 15.3226
400 1OS1 PYR 15.3226
401 1OS1 ATP 15.3226
402 3ITJ CIT 15.3226
403 2VB6 ADP BEF 15.4362
404 3QVV A3P 15.6757
405 1WF3 GNP 16.129
406 4CVN ADP 16.129
407 2BIF ANP 16.129
408 2BIF SIN 16.129
409 1XKV ATP 16.129
410 5X40 ACP 16.129
411 3TMK T5A 16.129
412 3P4X ADP 16.129
413 1Q19 SSC 16.129
414 1OE0 TTP 16.129
415 2QN6 GDP 16.2162
416 1KSH GDP 16.2162
417 3DOE GTP 16.2162
418 1SKQ GDP 16.2162
419 1GXU 2HP 16.4835
420 4RD0 GDP 16.7568
421 1F2U ATP 16.8919
422 4DCT GDP 16.9355
423 4AG5 ADP 16.9355
424 1P4V GLY 16.9355
425 1G7C 5GP 17.0213
426 4MKG AP5 17.0507
427 3PQC GDP 17.2973
428 3ZIA ADP 17.4603
429 3ZIA ATP 17.4603
430 1R4A GNP 17.5758
431 4ZG4 VO4 ADP 17.7419
432 4BQS ADP 17.7419
433 4BQS K2Q 17.7419
434 2J5V PCA 17.7419
435 2WZF BGC 17.7419
436 3PCR GTP 17.9012
437 1XEX ATP 18.1319
438 4PU6 ASP 18.3206
439 1YZG GDP 18.4358
440 3AQ4 GDP 18.4783
441 4H1V GNP 18.5484
442 1JJV ATP 18.5484
443 5DI3 GNP 18.9189
444 1F6B GDP 18.9189
445 1CR1 TTP 18.9189
446 3N5C GDP 19.1358
447 1MR3 G3D 19.337
448 3LRE ADP 19.3548
449 4MKF AP5 19.3548
450 1QF9 ALF 19.3548
451 1QF9 C5P 19.3548
452 1QF9 ADP 19.3548
453 2A5F GTP 19.4286
454 3W6G FLC 19.4595
455 1J2J GTP 19.8795
456 2J59 GTP 19.8795
457 1O3Y GTP 19.8795
458 2CHG ANP 20
459 1RE0 GDP 20.122
460 1S9D GDP 20.122
461 1YQT ADP 20.1613
462 2XTN GTP 20.1613
463 5L3R GCP 20.1613
464 3UIE ANP 20.1613
465 5VHC BEF ADP 20.1613
466 4YLG GDP 20.2312
467 5YV5 ADP 20.9677
468 2NCD ADP 20.9677
469 5UIV ADP 20.9677
470 4PJ3 ANP 20.9677
471 1BG2 ADP 22.5806
472 2XT3 ADP 22.5806
473 3QF7 ANP 22.5806
474 4PVR ASP 22.5806
475 4TMZ GSP 23.2432
476 6H5E ANP 23.2432
477 2KIN ADP 24
478 1B0U ATP 24.3243
479 5I0H ADP BEF 25
480 1GOT GDP 25.4054
481 4QOS ADP 25.8065
482 2GDJ ANP 25.8065
483 3FYH ADP 25.8065
484 5KUT GDP 25.9459
485 1FQJ ALF 25.9459
486 1FQK ALF 25.9459
487 1FQJ GDP 25.9459
488 1FQK GDP 25.9459
489 4V0K GDP 27.2189
490 5KSP GDP 27.3684
491 3EC1 GDP 27.4194
492 4NCN GTP 28.1081
493 5KSZ GCP 29.1892
494 1ZD9 GDP 30.2703
495 1TAD GDP 30.6452
496 1TAD ALF 30.6452
497 2W83 GTP 30.9091
498 2ZEJ GDP 30.9783
499 4KAX GTP 31.9527
500 4BAS GNP 32.2581
501 3E5H GNP 32.5843
502 2G77 GDP 32.973
503 2G77 AF3 32.973
504 1ZJ6 G3D 32.973
505 5KDO GDP 33.0645
506 5YT0 GDP 33.3333
507 3GJ4 GDP 33.5135
508 3GJ7 GDP 33.5135
509 3GJX GTP 33.5135
510 3GJ5 GDP 33.5135
511 3GJ8 GDP 33.5135
512 5DIF GNP 34.0541
513 5UWP GNP 34.0541
514 5UWQ GNP 34.0541
515 4HAT GNP 34.0541
516 5UWO GNP 34.0541
517 5UWW GNP 34.0541
518 5UWU GNP 34.0541
519 6CIT GNP 34.0541
520 5DHF GNP 34.0541
521 5UWT GNP 34.0541
522 5UWH GNP 34.0541
523 5UWS GNP 34.0541
524 3M1I GTP 34.0541
525 3WYF GTP 34.0541
526 3GJ0 GDP 34.0541
527 3GJ3 GDP 34.0541
528 5BXQ GDP 34.0541
529 5UWI GNP 34.0541
530 5UWJ GNP 34.0541
531 5UWR GNP 34.0541
532 1IBR GNP 34.0541
533 5DI9 GNP 34.0541
534 3CH5 GDP 34.0541
535 5OEC GDP 34.4262
536 5SZH GNP 34.5946
537 3TKL GTP 34.5946
538 3WYG GTP 34.6154
539 4XTR ATP 34.6774
540 4XVU ATP 34.6774
541 4XTR ADP 34.6774
542 3ZS9 ADP ALF 34.6774
543 2WOJ ADP ALF 34.6774
544 3SFV GDP 34.8066
545 5O74 GDP 35.5556
546 1WA5 GTP 35.7955
547 4ZI2 GNP 36.2162
548 4GOJ GNP 36.2162
549 3NKV GNP 36.5714
550 3WY9 GDP 37.5
551 1Z2A GDP 37.5
552 1FZQ GDP 37.5691
553 5XC5 GTP 38.6364
554 1BH2 GSP 38.7097
555 1SVK ALF GDP 38.7097
556 6CRK GDP 38.7097
557 1GP2 GDP 38.7097
558 1Y3A GDP 38.7097
559 2OM2 GDP 38.7097
560 1Z0J GTP 38.8235
561 3BC1 GNP 38.9189
562 1YVD GNP 40.2367
563 1Z06 GNP 40.5405
564 1MKY GDP 40.5405
565 2CJW GDP 41.0811
566 2EW1 GNP 42.1622
567 3RWO GDP 42.1622
568 2A5J GDP 42.1622
569 3CPJ GDP 42.1622
570 1OIX GDP 42.7027
571 1OIV GDP 43.2432
572 1VG9 GDP 43.7838
573 1VG1 GDP 43.7838
574 2BME GNP 43.7838
575 1VG0 GDP 43.7838
576 1VG8 GNP 43.7838
577 1X1R GDP 43.8202
578 2HT6 GDP 44.2529
579 3Q72 GNP 44.5783
580 5JCZ GDP 44.6927
581 5LEF GTP 44.8649
582 5TB5 GDP 44.8649
583 5TAR GDP 44.8649
584 4LX0 BEF GDP 45.1977
585 5Z2M GTP 45.4545
586 2HV8 GTP 45.9302
587 5OCG GNP 45.9459
588 2F9L GDP 45.9459
589 1TU3 GNP 46.1988
590 4C4P GNP 46.2428
591 3MJH GTP 46.4286
592 1EK0 GNP 46.4706
593 1R2Q GNP 46.4706
594 4DKX GDP 46.4865
595 1Z0K GTP 46.5116
596 5UQW GDP 46.5608
597 2Y8E GNP 46.9274
598 2BCG GDP 47.027
599 1G16 GDP 47.0588
600 1KY3 GDP 47.2527
601 2D7C GTP 47.3054
602 3Q85 GNP 47.3373
603 1Z0A GDP 47.7011
604 6FA4 GNP 47.9769
605 2EFE GNH 48.0663
606 1YZN GNP 48.1081
607 3QBT GNP 48.2759
608 3TNF GNP 48.2759
609 4LHW GNP 48.2759
610 1ZC3 GNP 48.5714
611 3T5G GDP 48.6188
612 1YZQ GNP 48.8235
613 1UAD GNP 49.1429
614 1Z0F GDP 49.162
615 2A9K GDP 49.1979
616 1D5C GDP 49.3827
617 6BSX GDP 49.4382
618 6BSX E7S 49.4382
619 3RAB GNP 49.7041
620 5O2T GSP 49.7041
621 4D0G GTP 49.7143
Pocket No.: 2; Query (leader) PDB : 2W2X; Ligand: GSP; Similar sites found with APoc: 33
This union binding pocket(no: 2) in the query (biounit: 2w2x.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 4PYA 2X3 None
2 1PTR PRB None
3 1PVN MZP 3.22581
4 3W9F I3P 3.24324
5 4CR6 MAN 3.78378
6 5XLS URA 4.03226
7 4NTO 1PW 4.32432
8 3KC1 2T6 4.32432
9 1VBO MAN 4.32432
10 3BP1 GUN 5.64516
11 1NST A3P 5.64516
12 2Z5F A3P 5.64516
13 1SQL GUN 6.16438
14 6FMC DUE 6.96203
15 3PA8 621 7.02703
16 5YLF BGC 7.25806
17 3BD9 A3P 8.06452
18 3FSY SCA 8.87097
19 3B2Q AES 8.87097
20 1I1N SAH 8.87097
21 4D5G TPP 10.2703
22 4U60 SIA GAL NGA 10.4839
23 4U60 SIA 10.4839
24 1JG3 ADN 10.8108
25 6MJ7 ARG 10.9091
26 1XVB BBX 12.0968
27 4ZUL UN1 12.0968
28 1Z0N BCD 12.5
29 1R18 SAH 14.5946
30 1AQU A3P 16.9355
31 2WCU FUC 17.7419
32 1JT1 MCO 18.9189
33 3AB4 LYS 21.7742
APoc FAQ
Feedback