Receptor
PDB id Resolution Class Description Source Keywords
2VQD 2.41 Å EC: 6.3.4.14 CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM PSEUDOMONAS AER COMPLEXED WITH AMPCP PSEUDOMONAS AERUGINOSA NUCLEOTIDE-BINDING FATTY ACID BIOSYNTHESIS LIPID SYNTHESISGRASP DOMAIN BIOTIN CARBOXYLASE LIGASE BIOTIN BACTERIABINDING
Ref.: STRUCTURAL EVIDENCE FOR SUBSTRATE-INDUCED SYNERGISM HALF-SITES REACTIVITY IN BIOTIN CARBOXYLASE. PROTEIN SCI. V. 17 1706 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
AP2 A:1448;
Valid;
none;
submit data
425.228 C11 H17 N5 O9 P2 c1nc(...
MG A:1449;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
SO4 A:1450;
Invalid;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2VQD 2.41 Å EC: 6.3.4.14 CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM PSEUDOMONAS AER COMPLEXED WITH AMPCP PSEUDOMONAS AERUGINOSA NUCLEOTIDE-BINDING FATTY ACID BIOSYNTHESIS LIPID SYNTHESISGRASP DOMAIN BIOTIN CARBOXYLASE LIGASE BIOTIN BACTERIABINDING
Ref.: STRUCTURAL EVIDENCE FOR SUBSTRATE-INDUCED SYNERGISM HALF-SITES REACTIVITY IN BIOTIN CARBOXYLASE. PROTEIN SCI. V. 17 1706 2008
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 2VQD - AP2 C11 H17 N5 O9 P2 c1nc(c2c(n....
70% Homology Family (29)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2W6O ic50 = 60.8 uM OA3 C10 H13 N3 O CC1(Cc2c(c....
2 3JZI ic50 = 5 uM JZL C23 H28 Cl N5 O2 c1ccc(c(c1....
3 3JZF ic50 = 5 uM JZK C22 H25 Cl N4 O c1ccc(c(c1....
4 3G8C - BTN C10 H16 N2 O3 S C1[C@H]2[C....
5 3RV3 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
6 2V59 Kd = 6.53 nM LZK C15 H15 N5 O2 COc1cccc(c....
7 2W70 ic50 = 12 uM L22 C7 H7 N5 S c1cnc(nc1c....
8 3RV4 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
9 2W6P ic50 = 0.333 uM OA4 C15 H14 N4 Cc1c(ccc2c....
10 3G8D - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
11 1DV2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
12 2V5A ic50 = 150 nM LZL C17 H15 N5 c1ccc(cc1)....
13 2W6N ic50 = 0.125 uM OA2 C18 H17 N3 O2 c1ccc(cc1)....
14 2W6M ic50 = 21.5 uM OA1 C10 H7 Br N2 O2 c1cc(cc(c1....
15 2W6Q ic50 = 25.4 uM OA5 C11 H13 N5 O2 c1ccc(cc1)....
16 2J9G - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
17 2W6Z ic50 = 1500 uM L21 C10 H13 N5 CC(=CCn1cn....
18 2V58 Kd = 0.82 nM LZJ C13 H9 Br2 N5 c1cc(c(c(c....
19 3RUP - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
20 2W71 ic50 = 0.334 uM L23 C15 H13 Cl2 N5 Cc1nc(cn1C....
21 2VQD - AP2 C11 H17 N5 O9 P2 c1nc(c2c(n....
22 4MV6 - PCT C2 H6 N O4 P C(C(=O)N)P....
23 4RZQ - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
24 4MV4 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
25 4MV1 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
26 4MV8 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
27 4MV7 - PPF C H3 O5 P C(=O)(O)P(....
28 4MV3 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
29 2VPQ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (29)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2W6O ic50 = 60.8 uM OA3 C10 H13 N3 O CC1(Cc2c(c....
2 3JZI ic50 = 5 uM JZL C23 H28 Cl N5 O2 c1ccc(c(c1....
3 3JZF ic50 = 5 uM JZK C22 H25 Cl N4 O c1ccc(c(c1....
4 3G8C - BTN C10 H16 N2 O3 S C1[C@H]2[C....
5 3RV3 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
6 2V59 Kd = 6.53 nM LZK C15 H15 N5 O2 COc1cccc(c....
7 2W70 ic50 = 12 uM L22 C7 H7 N5 S c1cnc(nc1c....
8 3RV4 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
9 2W6P ic50 = 0.333 uM OA4 C15 H14 N4 Cc1c(ccc2c....
10 3G8D - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
11 1DV2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
12 2V5A ic50 = 150 nM LZL C17 H15 N5 c1ccc(cc1)....
13 2W6N ic50 = 0.125 uM OA2 C18 H17 N3 O2 c1ccc(cc1)....
14 2W6M ic50 = 21.5 uM OA1 C10 H7 Br N2 O2 c1cc(cc(c1....
15 2W6Q ic50 = 25.4 uM OA5 C11 H13 N5 O2 c1ccc(cc1)....
16 2J9G - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
17 2W6Z ic50 = 1500 uM L21 C10 H13 N5 CC(=CCn1cn....
18 2V58 Kd = 0.82 nM LZJ C13 H9 Br2 N5 c1cc(c(c(c....
19 3RUP - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
20 2W71 ic50 = 0.334 uM L23 C15 H13 Cl2 N5 Cc1nc(cn1C....
21 2VQD - AP2 C11 H17 N5 O9 P2 c1nc(c2c(n....
22 4MV6 - PCT C2 H6 N O4 P C(C(=O)N)P....
23 4RZQ - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
24 4MV4 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
25 4MV1 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
26 4MV8 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
27 4MV7 - PPF C H3 O5 P C(=O)(O)P(....
28 4MV3 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
29 2VPQ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: AP2; Similar ligands found: 331
No: Ligand ECFP6 Tc MDL keys Tc
1 AP2 1 1
2 A12 1 1
3 APC 0.821918 1
4 RBY 0.810811 0.972973
5 ADV 0.810811 0.972973
6 AMP 0.808824 0.931507
7 A 0.808824 0.931507
8 ACP 0.808219 0.986301
9 ABM 0.774648 0.881579
10 A2D 0.774648 0.932432
11 AMP MG 0.760563 0.857143
12 BA3 0.753425 0.932432
13 SRA 0.746479 0.883117
14 B4P 0.743243 0.932432
15 ADP 0.743243 0.958904
16 AP5 0.743243 0.932432
17 AN2 0.733333 0.945946
18 M33 0.723684 0.92
19 ADX 0.723684 0.841463
20 CA0 0.723684 0.907895
21 AU1 0.723684 0.933333
22 ACQ 0.721519 0.986301
23 50T 0.714286 0.92
24 ATP 0.714286 0.958904
25 APR 0.705128 0.932432
26 AR6 0.705128 0.932432
27 5FA 0.705128 0.958904
28 PRX 0.705128 0.858974
29 AQP 0.705128 0.958904
30 ADP MG 0.701299 0.87013
31 ADP PO3 0.696203 0.905405
32 AGS 0.696203 0.909091
33 AD9 0.696203 0.933333
34 SAP 0.696203 0.909091
35 BEF ADP 0.692308 0.848101
36 ADP BEF 0.692308 0.848101
37 SON 0.688312 0.946667
38 ATP MG 0.6875 0.87013
39 TAT 0.679012 0.921053
40 ANP 0.679012 0.933333
41 GAP 0.679012 0.858974
42 5AL 0.670732 0.894737
43 ATF 0.662651 0.921053
44 SRP 0.654762 0.896104
45 AMO 0.643678 0.921053
46 4AD 0.643678 0.909091
47 ALF ADP 0.642857 0.8375
48 ADP ALF 0.642857 0.8375
49 DAL AMP 0.639535 0.87013
50 MAP 0.639535 0.909091
51 A22 0.639535 0.945946
52 VO4 ADP 0.635294 0.894737
53 ADP VO4 0.635294 0.894737
54 ANP MG 0.635294 0.860759
55 ADN 0.632353 0.810811
56 RAB 0.632353 0.810811
57 XYA 0.632353 0.810811
58 8QN 0.632184 0.894737
59 5SV 0.632184 0.839506
60 OOB 0.632184 0.894737
61 25A 0.632184 0.932432
62 TAD 0.631579 0.923077
63 ADQ 0.625 0.907895
64 A1R 0.625 0.922078
65 PAJ 0.625 0.851852
66 AOC 0.623377 0.789474
67 DLL 0.617977 0.894737
68 AHX 0.617977 0.886076
69 00A 0.617977 0.85
70 5N5 0.614286 0.786667
71 5AS 0.6125 0.752809
72 3UK 0.611111 0.883117
73 OAD 0.611111 0.907895
74 5CD 0.605634 0.773333
75 A4D 0.605634 0.786667
76 PR8 0.604396 0.864198
77 WAQ 0.604396 0.897436
78 LAD 0.604396 0.875
79 1ZZ 0.597826 0.831325
80 ME8 0.597826 0.831325
81 3OD 0.597826 0.907895
82 BIS 0.597826 0.897436
83 TXA 0.597826 0.896104
84 FYA 0.597826 0.894737
85 PTJ 0.597826 0.8625
86 NB8 0.597826 0.886076
87 M2T 0.594595 0.707317
88 ADP BMA 0.593407 0.883117
89 MYR AMP 0.591398 0.809524
90 25L 0.591398 0.945946
91 A A 0.586957 0.906667
92 9SN 0.585106 0.839506
93 EP4 0.581081 0.725
94 JB6 0.580645 0.873418
95 A3P 0.580247 0.931507
96 YAP 0.578947 0.884615
97 7D5 0.578947 0.868421
98 ATP A A A 0.578947 0.893333
99 FA5 0.578947 0.896104
100 DTA 0.573333 0.779221
101 TYR AMP 0.572917 0.848101
102 XAH 0.572917 0.853659
103 AFH 0.571429 0.875
104 3DH 0.571429 0.74359
105 G5A 0.569767 0.772727
106 4TC 0.568627 0.910256
107 4UV 0.56701 0.860759
108 MTA 0.565789 0.74359
109 UP5 0.564356 0.884615
110 3AM 0.564103 0.891892
111 G3A 0.561224 0.886076
112 A2P 0.560976 0.917808
113 DZD 0.560748 0.923077
114 LAQ 0.56 0.831325
115 4UU 0.555556 0.860759
116 G5P 0.555556 0.886076
117 LPA AMP 0.554455 0.809524
118 AMP DBH 0.55102 0.858974
119 A5A 0.550562 0.77907
120 GTA 0.55 0.853659
121 6RE 0.55 0.753086
122 TSB 0.549451 0.790698
123 NAX 0.54902 0.864198
124 4UW 0.54902 0.829268
125 S4M 0.548781 0.681818
126 ARG AMP 0.544554 0.821429
127 AHZ 0.544554 0.788235
128 SSA 0.544444 0.793103
129 PAP 0.54023 0.945205
130 7MD 0.54 0.853659
131 AR6 AR6 0.54 0.881579
132 YLP 0.539216 0.833333
133 48N 0.539216 0.886076
134 54H 0.538462 0.761364
135 VMS 0.538462 0.761364
136 52H 0.538462 0.752809
137 ZAS 0.5375 0.7375
138 A3N 0.536585 0.75641
139 J7C 0.536585 0.7625
140 IMO 0.536585 0.891892
141 NXX 0.533981 0.896104
142 NAI 0.533981 0.873418
143 TXD 0.533981 0.873418
144 DND 0.533981 0.896104
145 6V0 0.533981 0.8625
146 53H 0.532609 0.752809
147 5CA 0.532609 0.793103
148 2AM 0.531646 0.905405
149 7D3 0.53012 0.894737
150 TYM 0.528846 0.896104
151 AF3 ADP 3PG 0.528846 0.829268
152 TXE 0.528846 0.873418
153 ALF ADP 3PG 0.528846 0.829268
154 OMR 0.528846 0.843373
155 LA8 ALF 3PG 0.528846 0.829268
156 2A5 0.528736 0.907895
157 GP2 0.52809 0.923077
158 V3L 0.52809 0.932432
159 DSH 0.52439 0.740741
160 AP0 0.52381 0.8625
161 UPA 0.52381 0.873418
162 YLB 0.52381 0.833333
163 MAO 0.52381 0.77381
164 YLC 0.52381 0.853659
165 7D4 0.523256 0.894737
166 ATR 0.522727 0.931507
167 PPS 0.522222 0.841463
168 DSZ 0.521277 0.793103
169 LSS 0.521277 0.755556
170 NSS 0.521277 0.793103
171 P5A 0.520833 0.758242
172 A4P 0.518868 0.813953
173 5X8 0.517241 0.75641
174 NVA LMS 0.515789 0.736264
175 IOT 0.514019 0.845238
176 5AD 0.513889 0.716216
177 OVE 0.512195 0.87013
178 GJV 0.511905 0.743902
179 LEU LMS 0.510417 0.736264
180 7MC 0.509434 0.833333
181 139 0.509259 0.864198
182 ADJ 0.509259 0.843373
183 YLA 0.509259 0.833333
184 T5A 0.509259 0.855422
185 ITT 0.505747 0.905405
186 A2R 0.505376 0.945946
187 GSU 0.505155 0.772727
188 KAA 0.505155 0.766667
189 CNA 0.504587 0.896104
190 AYB 0.504587 0.823529
191 SFG 0.5 0.766234
192 6C6 0.5 0.896104
193 NAD 0.495495 0.894737
194 COD 0.495495 0.825581
195 BTX 0.495495 0.855422
196 4TA 0.495495 0.821429
197 YSA 0.49505 0.772727
198 SMM 0.494624 0.701149
199 SAM 0.494505 0.705882
200 A7D 0.494253 0.792208
201 BT5 0.491071 0.845238
202 SA8 0.488889 0.722892
203 A5D 0.488889 0.779221
204 MHZ 0.488636 0.712644
205 71V 0.488372 0.873418
206 A3G 0.488095 0.792208
207 M24 0.486957 0.819277
208 Y3J 0.486842 0.697368
209 A3D 0.486726 0.883117
210 7D7 0.486486 0.736842
211 NAD IBO 0.486486 0.8375
212 SAH 0.483516 0.759494
213 SAI 0.483516 0.75
214 G A A A 0.482143 0.839506
215 PO4 PO4 A A A A PO4 0.479592 0.866667
216 S7M 0.478723 0.705882
217 6IA 0.478261 0.829268
218 3AT 0.478261 0.958904
219 YLY 0.474138 0.823529
220 6AD 0.473118 0.875
221 EEM 0.473118 0.705882
222 PGS 0.47191 0.85
223 7C5 0.471154 0.7875
224 DA 0.470588 0.893333
225 NEC 0.470588 0.717949
226 D5M 0.470588 0.893333
227 NAE 0.470085 0.860759
228 NIA 0.46988 0.792683
229 NAJ PZO 0.469565 0.817073
230 2SA 0.468085 0.921053
231 AV2 0.468085 0.881579
232 NAQ 0.466102 0.839506
233 NAJ PYZ 0.466102 0.819277
234 AAM 0.465116 0.931507
235 U A G G 0.464912 0.85
236 NA7 0.464646 0.972973
237 A A A 0.464646 0.92
238 GEK 0.463918 0.753086
239 A U 0.463636 0.8375
240 C2R 0.463415 0.868421
241 AMZ 0.463415 0.88
242 4YB 0.462264 0.755556
243 ZID 0.462185 0.883117
244 N0B 0.462185 0.833333
245 AMP NAD 0.462185 0.848101
246 3AD 0.461538 0.797297
247 A3S 0.460674 0.802632
248 101 0.458824 0.868421
249 WSA 0.458716 0.781609
250 Z5A 0.458333 0.772727
251 AAT 0.457447 0.722892
252 AIR 0.455696 0.864865
253 ARU 0.454545 0.829268
254 EAD 0.454545 0.841463
255 GGZ 0.453608 0.795181
256 A3T 0.450549 0.789474
257 DAT 0.450549 0.92
258 A6D 0.45 0.717647
259 AVV 0.44898 0.910256
260 6K6 0.44898 0.893333
261 DTP 0.446809 0.92
262 649 0.445455 0.758242
263 0UM 0.444444 0.714286
264 8BR 0.443182 0.871795
265 NDE 0.44 0.896104
266 P1H 0.44 0.821429
267 N6P 0.44 0.878378
268 62X 0.44 0.681818
269 G2P 0.438776 0.923077
270 K15 0.435644 0.697674
271 S8M 0.434343 0.775
272 V1N 0.433962 0.881579
273 FB0 0.433071 0.83908
274 NDC 0.433071 0.8625
275 7RA 0.431818 0.918919
276 AS 0.431818 0.848101
277 QQY 0.430233 0.78481
278 ACK 0.430233 0.826667
279 CC5 0.428571 0.808219
280 GCP 0.428571 0.910256
281 SXZ 0.427184 0.72619
282 FDA 0.426357 0.825581
283 PLP AAD 0.423729 0.736264
284 KB1 0.423077 0.714286
285 6FA 0.423077 0.833333
286 TM1 0.423077 0.747126
287 NJP 0.422414 0.909091
288 2BA 0.422222 0.878378
289 CMP 0.422222 0.864865
290 7RP 0.420455 0.890411
291 2VA 0.419355 0.769231
292 0WD 0.418803 0.886076
293 QQX 0.418605 0.775
294 NPW 0.417391 0.876543
295 DDS 0.416667 0.868421
296 FAD 0.416667 0.843373
297 FAS 0.416667 0.843373
298 SFD 0.416667 0.729167
299 RMB 0.41573 0.837838
300 RP1 0.413793 0.810127
301 1RB 0.413793 0.849315
302 SP1 0.413793 0.810127
303 7DD 0.413043 0.945205
304 ANZ 0.412844 0.771084
305 APU 0.412281 0.860759
306 FAY 0.411765 0.853659
307 ODP 0.410256 0.875
308 D3Y 0.41 0.782051
309 U G A 0.409091 0.809524
310 5GP 0.408602 0.871795
311 G 0.408602 0.871795
312 SLU 0.408333 0.744444
313 U A C C 0.408333 0.82716
314 U A A U 0.408 0.873418
315 3L1 0.407407 0.789474
316 3D1 0.407407 0.789474
317 SO8 0.40625 0.759494
318 VRT 0.40625 0.7625
319 NDP 0.405172 0.886076
320 FNK 0.404412 0.797753
321 62F 0.404412 0.853659
322 3NZ 0.403846 0.775
323 26A 0.402439 0.734177
324 2FA 0.402439 0.782051
325 RGT 0.401869 0.921053
326 TXP 0.401709 0.886076
327 NZQ 0.401709 0.898734
328 P2P 0.4 0.866667
329 7DT 0.4 0.945205
330 FAI 0.4 0.88
331 NAD BBN 0.4 0.811765
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2VQD; Ligand: AP2; Similar sites found: 359
This union binding pocket(no: 1) in the query (biounit: 2vqd.bio1) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4U98 ACP 0.0007297 0.45345 1.10132
2 4O1P ANP 0.0004131 0.44125 1.2931
3 5HES 032 0.0011 0.43476 1.30293
4 5IQD RIO 0.00691 0.41983 1.31148
5 5IQD GNP 0.006534 0.41983 1.31148
6 2J7T 274 0.006529 0.4125 1.3245
7 5VC5 96M 0.0008231 0.44906 1.38408
8 2WOJ ADP ALF 0.003012 0.4229 1.41243
9 2IO8 ADP 0.00001539 0.48711 1.50862
10 4P5Z Q7M 0.004096 0.43014 1.66205
11 4AZW ATP 0.002225 0.41982 1.69851
12 2PYW ADP 0.0001714 0.46691 1.72414
13 5MW8 ATP 0.0002317 0.46561 1.72414
14 1M0W ANP 0.00007076 0.45825 1.72414
15 3IGO ANP 0.0005501 0.43989 1.72414
16 3PE2 E1B 0.0003 0.48989 1.78042
17 3FHR P4O 0.006176 0.40438 1.78571
18 5IH9 6BF 0.0001831 0.48855 1.79104
19 3GC0 AMP 0.0001077 0.44626 1.82371
20 5MY8 RXZ 0.0005807 0.45224 1.82768
21 4Y0X ADP 0.0000638 0.46213 1.86667
22 4LOO SB4 0.001881 0.41509 1.93906
23 4L3L 5FI 0.0001803 0.48126 1.93966
24 4FL3 ANP 0.0009036 0.43002 1.93966
25 4NFN 2KC 0.007394 0.40801 1.94175
26 5LXC 7AA 0.000145 0.44977 1.96078
27 5MJA 7O3 0.0006539 0.42349 1.96721
28 4ASE AV9 0.003482 0.42168 1.983
29 4IX4 ADP 0.0003084 0.45613 2
30 5T8O 76Z 0.0003157 0.4557 2.00573
31 2CSN CKI 0.001344 0.43814 2.0202
32 3DNT ATP 0.007117 0.40355 2.04545
33 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.002088 0.45891 2.04678
34 2JDR L20 0.002088 0.45891 2.04678
35 3GNI ATP 0.001376 0.42866 2.05656
36 4WNP 3RJ 0.0006386 0.42117 2.09059
37 2PZI AXX 0.001814 0.44472 2.15517
38 5EOB 5QQ 0.003173 0.44868 2.19436
39 2F57 23D 0.0006876 0.42215 2.2082
40 4TWP AXI 0.002838 0.44373 2.21402
41 5U6C 7YS 0.0005957 0.44609 2.22222
42 2QLU ADE 0.001416 0.46063 2.2293
43 5TA6 79D 0.001753 0.43471 2.23464
44 4XLI 1N1 0.001972 0.41118 2.23881
45 3NW7 LGV 0.006632 0.42761 2.28013
46 3OFM 4B0 0.00003313 0.46726 2.28571
47 5I35 ANP 0.0005024 0.43085 2.29008
48 1U5R ATP 0.000532 0.45965 2.29885
49 4YMJ 4EJ 0.00036 0.49843 2.30263
50 2RIO ADP 0.0006314 0.42982 2.30415
51 5HX8 66P 0.0003423 0.42596 2.31788
52 4ME6 ADP 0.0003674 0.40969 2.33161
53 5C03 AGS 0.0002376 0.44988 2.33918
54 1K3A ACP 0.0003655 0.4277 2.34114
55 2YNE NHW 0.01257 0.43478 2.34375
56 2YNE YNE 0.01257 0.43478 2.34375
57 4FE2 ADP 0.0005367 0.46973 2.35294
58 4WNK 453 0.001879 0.43638 2.37069
59 4ANW O92 0.009063 0.40875 2.37069
60 4BTK DTQ 0.002217 0.41073 2.37389
61 3DLS ADP 0.0008694 0.42082 2.38806
62 4BHN BH9 0.001856 0.42316 2.39521
63 1Q8Y ADP 0.0007421 0.44 2.41287
64 1Q8Y ADE 0.00015 0.42655 2.41287
65 4DFU QUE 0.005446 0.43624 2.48447
66 4GYI ADP 0.0003304 0.4797 2.51889
67 1GSA ADP 0.0000008673 0.56944 2.53165
68 1Q8A HCS 0.01584 0.41369 2.58621
69 4ZS4 ATP 0.0001186 0.46924 2.60586
70 5GZ9 ANP 0.0006476 0.44651 2.62295
71 2WU6 DKI 0.0001857 0.45201 2.62467
72 3C1X CKK 0.005081 0.40645 2.68097
73 3KRL KRL 0.003171 0.41518 2.68657
74 4BFM ANP 0.0002388 0.46082 2.69461
75 4OH4 ANP 0.00009781 0.48737 2.7027
76 2X4Z X4Z 0.0004182 0.47106 2.7027
77 5LPZ ADP 0.0002174 0.45296 2.71084
78 1OUK 084 0.005466 0.46065 2.73224
79 4CLI 5P8 0.0005815 0.47443 2.75229
80 3UIM ANP 0.0001128 0.46392 2.76074
81 5UIU 8CG 0.0003571 0.46818 2.78638
82 1U59 STU 0.002671 0.42397 2.78746
83 2WEI VGG 0.001338 0.41126 2.78746
84 3G5D 1N1 0.004529 0.44218 2.7972
85 5HVJ ANP 0.0002275 0.50672 2.80172
86 3PLS ANP 0.0000808 0.4637 2.80172
87 1Y57 MPZ 0.003666 0.41427 2.80172
88 4OAV ACP 0.001691 0.41231 2.80172
89 3VRY B43 0.001041 0.41146 2.80172
90 4L9I 8PR 0.002197 0.40951 2.80172
91 2JLD AG1 0.0006374 0.40527 2.80172
92 5LXM ADP 0.001036 0.42095 2.82686
93 1TQP ATP 0.0008376 0.42164 2.83688
94 4BKJ STI 0.002303 0.42635 2.85714
95 4X7Q 3YR 0.001699 0.43265 2.88462
96 2OFV 242 0.00155 0.44684 2.88809
97 3SRV S19 0.0006287 0.43004 2.88809
98 2Q7D ANP 0.000182 0.43823 2.89017
99 4OCV ANP 0.0001187 0.46936 2.90237
100 3PDT ADP 0.0007371 0.4581 2.90909
101 3MVH WFE 0.0009633 0.44918 2.92398
102 4F4P 0SB 0.03472 0.4021 2.9304
103 1OBD ATP 0.001373 0.40431 2.94118
104 5EW9 5VC 0.00763 0.45332 2.95203
105 5UOX 8GY 0.002693 0.4182 2.95203
106 2HK5 1BM 0.001927 0.42247 2.96296
107 3GC8 B45 0.001278 0.42422 2.97297
108 3SXS PP2 0.001738 0.42436 2.98507
109 3E5A VX6 0.0006624 0.42105 2.98507
110 3ZS7 ATP 0.003987 0.41271 3
111 3EZ2 ADP 0.01559 0.40842 3.01508
112 4UAL 3FV 0.0005106 0.43969 3.01724
113 3VSV XYS 0.00946 0.4253 3.01724
114 3TTI KBI 0.001096 0.40381 3.01724
115 5HCY 60D 0.00204 0.44934 3.02115
116 5LPB ADP 0.0004052 0.42358 3.04054
117 5DBX ANP 0.0001682 0.43965 3.04878
118 4KS7 X4Z 0.00006428 0.46987 3.08219
119 3ZQ6 ADP ALF 0.01074 0.40024 3.08642
120 4LH7 1X8 0.003786 0.44802 3.09598
121 3DAK ANP 0.00008341 0.50179 3.10345
122 5LI1 ANP 0.0002835 0.45981 3.10734
123 2PVN P63 0.0001928 0.42442 3.125
124 5LI9 ACP 0.0003729 0.45707 3.14286
125 4OCJ NDG 0.0004264 0.47466 3.16623
126 5G1X ADP 0.000715 0.42755 3.1746
127 4JD0 1KH 0.01735 0.41189 3.23276
128 3TDV GDP 0.002349 0.42643 3.26797
129 3SLS ANP 0.0005852 0.43876 3.28947
130 5JZJ AN2 0.0002453 0.44533 3.367
131 4NST ADP 0.0005173 0.43703 3.4188
132 3AI3 SOL 0.004016 0.44301 3.42205
133 1KWK GAL 0.02514 0.40212 3.44828
134 4NM5 ADP 0.03014 0.40012 3.44828
135 5EFQ ADP 0.0003311 0.44516 3.45821
136 4JR7 GNP 0.0002768 0.44857 3.47594
137 3ZRM ZRM 0.0001164 0.46398 3.50404
138 4IZY 1J2 0.0003851 0.45205 3.52304
139 2WQN ADP 0.0004223 0.47466 3.54839
140 4UX9 ANP 0.0001044 0.47603 3.57143
141 4I6H 1C8 0.002266 0.42712 3.57143
142 4H3P ANP 0.0000986 0.46698 3.59116
143 1BYG STU 0.0002921 0.43435 3.59712
144 5BVE 4VG 0.001064 0.47603 3.60111
145 4WHZ 3NL 0.002303 0.45081 3.63636
146 4CSV STI 0.003289 0.41629 3.63636
147 4OUC 5ID 0.0005858 0.42514 3.64146
148 4N70 2HX 0.0007065 0.47471 3.65854
149 3LXK MI1 0.0001247 0.43349 3.66972
150 2B9J ADP 0.00008309 0.49603 3.68272
151 2B9I ADP 0.0001521 0.47891 3.68272
152 2B9H ADP 0.00009632 0.47247 3.68272
153 2B9F ADP 0.00008822 0.4691 3.68272
154 3KN5 ANP 0.0003353 0.42921 3.69231
155 4CS9 AMP 0.01413 0.40876 3.7037
156 1YB5 NAP 0.01243 0.40608 3.7037
157 1O9U ADZ 0.000006139 0.59572 3.71429
158 3F7Z 34O 0.001599 0.41872 3.71429
159 5C4L 4XR 0.002909 0.4294 3.73832
160 4XV1 904 0.0005714 0.4636 3.76712
161 1XJD STU 0.0007369 0.43644 3.76812
162 2GQS ADP 0.0002182 0.44662 3.79747
163 5JGA 6KC 0.002555 0.43325 3.80952
164 3CY2 MB9 0.002033 0.42524 3.82166
165 4WW7 AMP 0.0003875 0.45404 3.83142
166 5DMZ ADP 0.001069 0.44154 3.83562
167 4H3Q ANP 0.00008992 0.4832 3.8674
168 2V7O DRN 0.0006773 0.41199 3.86905
169 2R7K AMZ 0.003578 0.42263 3.87812
170 5CEO 50D 0.0004663 0.43917 3.87931
171 3PUR 2HG 0.0201 0.40813 3.87931
172 3E7O 35F 0.003958 0.42479 3.88889
173 4U44 3D9 0.003274 0.40752 3.91566
174 4CQE CQE 0.003032 0.40892 3.95683
175 1ZY5 ANP 0.000835 0.42648 3.9604
176 3M2W L8I 0.0002596 0.4333 4.01338
177 4CRL C1I 0.003701 0.42737 4.09483
178 2IF8 ADP 0.0002947 0.50093 4.13223
179 2VZ6 FEF 0.005048 0.42368 4.15335
180 5VCV 1N1 0.003381 0.41749 4.18006
181 4IJP 1EH 0.00112 0.43243 4.18994
182 4R78 AMP 0.0005928 0.40862 4.20712
183 1VJY 460 0.001224 0.44746 4.29043
184 3GGF GVD 0.003985 0.42423 4.31894
185 2VN9 GVD 0.0005728 0.41236 4.31894
186 3TKI S25 0.002333 0.45413 4.33437
187 4JDI ANP 0.0003954 0.45156 4.33526
188 2HY0 306 0.002099 0.44172 4.34783
189 1PHK ATP 0.0003821 0.44757 4.36242
190 3KRR DQX 0.0006191 0.48887 4.40678
191 4E1Z 0MX 0.0001455 0.45622 4.46735
192 3X01 AMP 0.00002143 0.5641 4.52586
193 5JFS 6K0 0.001548 0.45161 4.54545
194 5AX9 4KT 0.002792 0.40278 4.54545
195 3EKK GS2 0.003397 0.43268 4.56026
196 3BU5 ATP 0.002722 0.40809 4.57516
197 3ALN ANP 0.001568 0.42625 4.58716
198 5KO1 6UY 0.0001205 0.45736 4.59364
199 5TO8 7FM 0.0009295 0.46054 4.60993
200 5DEY 59T 0.00189 0.45843 4.7138
201 3HMO STU 0.0003194 0.46964 4.74138
202 5N87 N66 0.001031 0.45481 4.74138
203 4D2S DYK 0.0009645 0.41054 4.74138
204 2X2M X2M 0.002181 0.4221 4.77707
205 1AUX AGS 0.0000001767 0.60841 4.82315
206 5JKG 6LF 0.008073 0.41676 4.82315
207 2YAK OSV 0.0003669 0.46766 4.91228
208 4USF 6UI 0.0007834 0.44483 4.93421
209 2XVD AS6 0.001279 0.44226 4.9569
210 4EUU BX7 0.0002709 0.46839 5.01567
211 4WOV 3SM 0.001035 0.45626 5.04732
212 2PVF ACP 0.0003727 0.46662 5.08982
213 2Z49 AMG 0.003685 0.44091 5.09259
214 2Z48 A2G 0.01785 0.41621 5.09259
215 2HGS ADP 0.0000402 0.49815 5.17241
216 4QTB 38Z 0.0002256 0.47532 5.26316
217 2XK9 XK9 0.0004747 0.46995 5.2795
218 4Y93 746 0.000666 0.44967 5.38117
219 3RI1 3RH 0.0001073 0.48586 5.43131
220 4M69 ANP 0.0002584 0.45937 5.43131
221 5UR1 YY9 0.008352 0.42016 5.46624
222 5FBN 5WF 0.0006359 0.4629 5.53506
223 5AWM ANP 0.0004459 0.42033 5.58376
224 5LXT ACP 0.00001781 0.4935 5.59441
225 3SXF BK5 0.0006906 0.4613 5.60345
226 1W2D ADP 0.0001599 0.50081 5.66038
227 2Z7R STU 0.00017 0.45987 5.81897
228 4CYI ATP 0.002983 0.41443 5.81897
229 4K33 ACP 0.0002794 0.45339 5.84615
230 4IDT T28 0.001455 0.43993 5.89888
231 1V0O INR 0.00297 0.41814 5.90278
232 4YZN 4K5 0.0009456 0.43947 5.92335
233 1PK8 ATP 0.0000002645 0.54712 6.03448
234 4QMN DB8 0.0004125 0.47269 6.03448
235 4EN4 GT1 0.009166 0.4153 6.08974
236 4EN4 GT0 0.009166 0.4153 6.08974
237 4EN4 ATP 0.009166 0.4153 6.08974
238 2Y6O 1N1 0.001936 0.4166 6.18557
239 3Q60 ATP 0.0004115 0.43638 6.19946
240 5HQ0 LZ9 0.0001942 0.46462 6.22711
241 3HAV ATP 0.002598 0.42569 6.25
242 2GQR ADP 0.0001831 0.44989 6.32911
243 4FG8 ATP 0.0007751 0.4392 6.34921
244 5A6N U7E 0.0005558 0.44216 6.36042
245 4Y8D 49J 0.0008857 0.44514 6.42857
246 3ORK AGS 0.0005052 0.42377 6.43087
247 2PUL ACP 0.00009401 0.49361 6.54912
248 5W2I I3P 0.0002329 0.4675 6.61479
249 5W2I ADP 0.0002329 0.4675 6.61479
250 5W4W 9WG 0.004456 0.42119 6.64653
251 4KBA 1QM 0.01726 0.4062 6.64653
252 2WEL K88 0.0001046 0.4228 6.66667
253 4U0I 0LI 0.004665 0.4203 6.66667
254 4YLL 4E3 0.000219 0.46666 6.68103
255 4YZC STU 0.001596 0.44749 6.68103
256 3AKK ADP 0.0003647 0.44874 6.76923
257 3I0O ADP 0.0001664 0.49997 6.78466
258 1Z2P I3S 0.0000831 0.4023 6.79012
259 1Z2P ACP 0.0000831 0.4023 6.79012
260 3TXO 07U 0.0002968 0.43926 6.79887
261 4O4F ATP 0.002221 0.42703 6.85484
262 4O4F IHP 0.002582 0.42581 6.85484
263 3ETH ATP 0.000002089 0.55053 6.89655
264 5USZ SKE 0.0001493 0.48145 6.92042
265 2CFM AMP 0.00434 0.43131 6.95187
266 3KMW ATP 0.0002481 0.47459 6.97674
267 1ZTH ADP 0.001013 0.4082 6.97674
268 1ZP9 ATP 0.001633 0.40795 6.97674
269 1U72 NDP 0.03152 0.40139 6.98925
270 4AU8 Z3R 0.002672 0.44154 7.09459
271 1IA9 ANP 0.00001458 0.51787 7.11207
272 1UNH IXM 0.0008276 0.41464 7.19178
273 3O0G 3O0 0.003339 0.40047 7.19178
274 4C2W ANP 0.0003019 0.42797 7.69231
275 2BKK ADP 0.001971 0.41253 7.69231
276 2YAB AMP 0.0007811 0.43522 7.75623
277 3ZS9 ADP ALF 0.002448 0.4024 7.89474
278 3GQI ACP 0.0009068 0.42789 7.9646
279 5M06 ADP 0.0001897 0.4438 7.97101
280 2E40 LGC 0.02595 0.40175 7.97414
281 3QCQ 3Q0 0.006391 0.45092 8.01282
282 1RE8 BD2 0.0002765 0.49153 8.28571
283 3FHI ANP 0.0002535 0.46964 8.28571
284 2QCS ANP 0.000377 0.46215 8.28571
285 3IDB ANP 0.0005097 0.43449 8.28571
286 3RE4 TO1 0.01115 0.4114 8.40517
287 3V8S 0HD 0.0001166 0.45911 8.53659
288 5DRB 5FJ 0.002898 0.44429 8.59107
289 1CM8 ANP 0.00087 0.4231 8.71935
290 1EHI ADP 0.000004683 0.53917 8.75332
291 4CFU 2WC 0.0005218 0.46503 8.91089
292 4BCM T7Z 0.00005822 0.4332 8.9701
293 4BCN T9N 0.001258 0.45224 9
294 2XMY CDK 0.001794 0.46743 9.0604
295 4C2V YJA 0.003879 0.42249 9.09091
296 5J1J ANP 0.001802 0.42748 9.12281
297 4XYM A12 0.0004607 0.44341 9.13043
298 5X8I SQZ 0.0002489 0.45113 9.24856
299 3TY3 GGG 0.02229 0.40955 9.28962
300 5L8L ADP 0.0005508 0.42107 9.40171
301 3UDZ ADP 0.0001237 0.46762 9.48276
302 3LXN MI1 0.0001593 0.46826 9.69828
303 4GJ3 0XP 0.001388 0.44364 9.69828
304 2ZV2 609 0.002047 0.44715 9.73154
305 3TII ANP 0.00001253 0.47544 9.73684
306 4JLS 3ZE 0.02737 0.40245 9.86842
307 3WO0 ALA 0.00006019 0.51316 10.1293
308 2F2U M77 0.002325 0.44446 10.199
309 3VPC ADP 0.0000001167 0.58921 10.2837
310 3VPB ADP 0.0000001117 0.56048 10.2837
311 4A4X JUP 0.00021 0.47319 10.3943
312 5BYZ 4WE 0.009579 0.40643 10.5603
313 4XH0 ADP 0.001073 0.47547 10.67
314 3VRV YSD 0.0233 0.40464 11.0701
315 4OTH DRN 0.0002109 0.46527 11.1437
316 4LRJ ANP 0.0001941 0.47941 11.8343
317 5EYK 5U5 0.003713 0.42046 11.8644
318 2R5T ANP 0.0004372 0.44304 12.2845
319 5H2U 1N1 0.003072 0.40515 12.3596
320 2QK4 ATP 0.0004826 0.40575 12.3894
321 5DA3 58V 0.001025 0.4617 12.4528
322 5TDF ADP 0.001377 0.42864 12.931
323 2GUC MAN 0.007887 0.42407 13.1148
324 2NU5 NAG 0.009149 0.41981 13.1148
325 2NUO BGC 0.01055 0.41504 13.1148
326 2HYR BGC GLC 0.01215 0.40855 13.1148
327 2A19 ANP 0.0005727 0.47396 13.1429
328 3PVW QRX 0.001173 0.40914 13.5135
329 1G27 BB1 0.006261 0.40761 13.6905
330 2AQX ATP 0.002426 0.42013 13.8408
331 3WVR AMP 0.00001638 0.48496 14.8707
332 3C0G 3AM 0.0003644 0.43072 15.0997
333 1I7L ATP 0.000001376 0.52797 15.534
334 5UKL SIX 0.003958 0.41924 16.129
335 5K2M ADP 0.0000001227 0.60853 16.8498
336 2R85 AMP 0.005072 0.41869 17.0659
337 4Q5H ANP 0.0002459 0.46971 18.9655
338 3VOT ADP 0.00006651 0.44459 19.0588
339 1T36 ADP 0.00006457 0.49734 19.3966
340 1KJ8 ATP 0.00008703 0.4111 20.4604
341 1KJ8 GAR 0.00009345 0.40655 20.4604
342 3JUC PCA 0.0185 0.41047 21.5686
343 3K5I ADP 0.000004149 0.53525 21.8362
344 3K5I AIR 0.0000408 0.43702 21.8362
345 3ORQ ADP 0.0000000138 0.64002 22.2812
346 4F9C 0SX 0.00006871 0.4687 24.3056
347 2GU8 796 0.0005069 0.48714 25
348 4WB6 ATP 0.0004318 0.45958 25
349 3V4S ATP 0.0000009063 0.55389 25.431
350 3V4S ADP 0.000003879 0.44892 25.431
351 3LQV ADE 0.02264 0.40154 25.641
352 5C1P DAL DAL 0.00007484 0.49073 26.7974
353 5C1P ADP 0.00001469 0.48507 26.7974
354 1E4E ADP 0.00008502 0.47561 27.6968
355 1IOW ADP 0.000002642 0.56957 29.085
356 1IOW PHY 0.000002642 0.56957 29.085
357 2YW2 ATP 0.001075 0.43318 29.2453
358 3VPD ANP 0.000008845 0.52387 33.0961
359 5LVP ATP 0.0001803 0.44079 40
Feedback