Receptor
PDB id Resolution Class Description Source Keywords
2VDY 2.3 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THE REACTIVE LOOP CLEAVED CORTICOSTEROI GLOBULIN COMPLEXED WITH CORTISOL HOMO SAPIENS GLYCOPROTEIN LIPID-BINDING STEROID-BINDING DISEASE MUTATICORTICOSTEROID BINDING GLOBULIN TRANSPORT PROTEIN CBG SECLEAVED SECRETED CORTISOL TRANSPORT
Ref.: THE S-TO-R TRANSITION OF CORTICOSTEROID-BINDING GLO THE MECHANISM OF HORMONE RELEASE. J.MOL.BIOL. V. 380 244 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
HCY A:1384;
B:1384;
Valid;
Valid;
none;
none;
submit data
362.46 C21 H30 O5 C[C@]...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2VDY 2.3 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THE REACTIVE LOOP CLEAVED CORTICOSTEROI GLOBULIN COMPLEXED WITH CORTISOL HOMO SAPIENS GLYCOPROTEIN LIPID-BINDING STEROID-BINDING DISEASE MUTATICORTICOSTEROID BINDING GLOBULIN TRANSPORT PROTEIN CBG SECLEAVED SECRETED CORTISOL TRANSPORT
Ref.: THE S-TO-R TRANSITION OF CORTICOSTEROID-BINDING GLO THE MECHANISM OF HORMONE RELEASE. J.MOL.BIOL. V. 380 244 2008
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 2VDY - HCY C21 H30 O5 C[C@]12CCC....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 2VDY - HCY C21 H30 O5 C[C@]12CCC....
2 2V95 - HCY C21 H30 O5 C[C@]12CCC....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 4PYW - ACE THR THR ALA ILE NH2 n/a n/a
2 2VDY - HCY C21 H30 O5 C[C@]12CCC....
3 2V95 - HCY C21 H30 O5 C[C@]12CCC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: HCY; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 HCY 1 1
2 C0R 0.551724 0.933333
3 AS4 0.544444 0.911111
4 ZK5 0.451613 0.918367
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2VDY; Ligand: HCY; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2vdy.bio2) has 13 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 2VDY; Ligand: HCY; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2vdy.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
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