Receptor
PDB id Resolution Class Description Source Keywords
2V8E 2.5 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF HUMAN COMPLEMENT FACTOR H, SCR DOMAINS RISK VARIANT), IN COMPLEX WITH LIGAND. HOMO SAPIENS ALTERNATIVE SPLICING SUCROSE OCTASULPHATE AGE-RELATED MACUDEGENERATION SUSHI SECRETED FACTOR H COMPLEMENT POLYMOCOMPLEMENT ALTERNATE PATHWAY IMMUNE SYSTEM DISEASE MUTATIGLYCOSAMINOGLYCAN GLYCOPROTEIN INNATE IMMUNITY IMMUNE RE
Ref.: STRUCTURAL BASIS FOR COMPLEMENT FACTOR H LINKED AGE MACULAR DEGENERATION. J.EXP.MED. V. 204 2277 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CL A:1508;
A:1509;
 Invalid;
Invalid;
 none;
none;
 submit data
35.453 Cl [Cl-]
GOL A:1513;
 Invalid;
 none;
 submit data
92.094 C3 H8 O3 C(C(C...
SO4 A:1510;
A:1511;
A:1512;
 Invalid;
Invalid;
Invalid;
 none;
none;
none;
 submit data
96.063 O4 S [O-]S...
GU4 YYJ B:1;
 Valid;
 none;
 submit data
974.737 n/a S(=O)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2UWN 2.35 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF HUMAN COMPLEMENT FACTOR H, SCR DOMAINS RISK VARIANT), IN COMPLEX WITH LIGAND. HOMO SAPIENS ALTERNATIVE SPLICING SUCROSE OCTASULPHATE AGE-RELATED MACUDEGENERATION COMPLEMENT ALTERNATE PATHWAY DISEASE MUTATIOGLYCOSAMINOGLYCAN GLYCOPROTEIN INNATE IMMUNITY IMMUNE RESUSHI FACTOR H COMPLEMENT POLYMORPHISM IMMUNE SYSTEM
Ref.: STRUCTURAL BASIS FOR COMPLEMENT FACTOR H LINKED AGE MACULAR DEGENERATION. J.EXP.MED. V. 204 2277 2007
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 2V8E - GU4 YYJ n/a n/a
2 2UWN - GU4 YYJ n/a n/a
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 2V8E - GU4 YYJ n/a n/a
2 2UWN - GU4 YYJ n/a n/a
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 2V8E - GU4 YYJ n/a n/a
2 2UWN - GU4 YYJ n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: GU4 YYJ; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 GU4 YYJ 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: GU4 YYJ; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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