-->
Receptor
PDB id Resolution Class Description Source Keywords
2RFX 2.5 Å NON-ENZYME: IMMUNE CRYSTAL STRUCTURE OF HLA-B*5701, PRESENTING THE SELF PEPTIDE LSSPVTKSF HOMO SAPIENS ALPHA BETA SANDWICH-IMMUNOLOGLOBULIN LIKE GLYCOPROTEIN HOSINTERACTION IMMUNE RESPONSE MEMBRANE MHC I TRANSMEMBRANDISEASE MUTATION GLYCATION IMMUNOGLOBULIN DOMAIN PYRROLICARBOXYLIC ACID SECRETED IMMUNE SYSTEM
Ref.: HUMAN LEUKOCYTE ANTIGEN CLASS I-RESTRICTED ACTIVATI CD8+ T CELLS PROVIDES THE IMMUNOGENETIC BASIS OF A DRUG HYPERSENSITIVITY IMMUNITY V. 28 822 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:3731;
A:3732;
B:3731;
B:3732;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
LEU SER SER PRO VAL THR LYS SER PHE C:1;
Valid;
none;
submit data
951.133 n/a O=C(N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2RFX 2.5 Å NON-ENZYME: IMMUNE CRYSTAL STRUCTURE OF HLA-B*5701, PRESENTING THE SELF PEPTIDE LSSPVTKSF HOMO SAPIENS ALPHA BETA SANDWICH-IMMUNOLOGLOBULIN LIKE GLYCOPROTEIN HOSINTERACTION IMMUNE RESPONSE MEMBRANE MHC I TRANSMEMBRANDISEASE MUTATION GLYCATION IMMUNOGLOBULIN DOMAIN PYRROLICARBOXYLIC ACID SECRETED IMMUNE SYSTEM
Ref.: HUMAN LEUKOCYTE ANTIGEN CLASS I-RESTRICTED ACTIVATI CD8+ T CELLS PROVIDES THE IMMUNOGENETIC BASIS OF A DRUG HYPERSENSITIVITY IMMUNITY V. 28 822 2008
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 208 families.
1 2RFX - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
70% Homology Family (360)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 62 families.
1 4QRT - GLU LEU ASN ARG LYS MET ILE TYR MET n/a n/a
2 3KPN - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
3 4U1H - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
4 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
5 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
6 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
7 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
8 5IND - GLN ALA SER GLN ASP VAL LYS ASN TRP n/a n/a
9 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
10 5V5L - THR SER THR LEU GLN GLU GLN ILE GLY TRP n/a n/a
11 5DEG - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
12 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
13 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
14 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
15 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
16 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
17 5WMP - THR PRO ARG VAL THR GLY GLY GLY ALA MET n/a n/a
18 5DEF - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
19 4U1M - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
20 5IM7 - GLN ALA SER GLN GLU VAL LYS ASN TRP n/a n/a
21 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
22 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
23 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
24 5WMR - GLN ILE LYS VAL ARG VAL ASP MET VAL n/a n/a
25 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
26 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
27 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
28 5EO0 - ARG PRO MET THR PHE LYS GLY ALA LEU n/a n/a
29 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
30 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
31 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
32 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
33 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
34 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
35 6BXP - ARG VAL LYS GLU LYS TYR GLN HIS LEU KYN n/a n/a
36 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
37 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
38 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
39 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
40 4U1N - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
41 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
42 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
43 5WMN - SER PRO ILE VAL PRO SER PHE ASP MET n/a n/a
44 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
45 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
46 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
47 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
48 4U1S - PHE PRO ARG PRO TRP LEU HIS GLY LEU n/a n/a
49 4U1K - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
50 5U98 Kd = 0.2 nM VAL THR THR ASP ILE GLN VAL LYS VAL n/a n/a
51 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
52 4XXC - ASP GLU LEU GLU ILE LYS ALA TYR n/a n/a
53 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
54 4QRQ Kd = 2.48 uM HIS SER LYS LYS LYS CYS ASP GLU LEU n/a n/a
55 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
56 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
57 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
58 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
59 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
60 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
61 5WMO - ARG PRO PRO ILE PHE ILE ARG ARG LEU n/a n/a
62 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
63 4U1L - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
64 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
65 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
66 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
67 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
68 5W67 - VAL ARG SER ARG ARG ABA LEU ARG LEU n/a n/a
69 5EO1 - ARG PRO MET THR TYR LYS GLY ALA LEU n/a n/a
70 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
71 5TXS - ALA GLN ASP ILE TYR ARG ALA SER TYR n/a n/a
72 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
73 5WMQ - GLU LEU ARG SER ARG TYR TRP ALA ILE n/a n/a
74 4QRS - GLU LEU LYS ARG LYS MET ILE TYR MET n/a n/a
75 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
76 4U1I - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
77 6BXQ - ARG VAL LYS GLU LYS TYR GLN HIS LEU TRP n/a n/a
78 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
79 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
80 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
81 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
82 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
83 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
84 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
85 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
86 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
87 4U1J - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
88 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
89 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
90 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
91 5VGD - SER ALA GLU PRO VAL PRO LEU GLN LEU n/a n/a
92 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
93 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
94 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
95 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
96 5T6W - SER SER THR ARG GLY ILE SER GLN LEU TRP n/a n/a
97 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
98 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
99 4QRU - GLU LEU ARG ARG LYS MET MET TYR MET n/a n/a
100 5W6A - ALA ARG THR GLU LEU TYR ARG SER LEU n/a n/a
101 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
102 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
103 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
104 5T6X - THR SER THR THR SER VAL ALA SER SER TRP n/a n/a
105 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
106 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
107 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
108 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
109 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
110 1B0G - ALA LEU TRP GLY PHE PHE PRO VAL LEU n/a n/a
111 3GSW - ASN LEU VAL PRO MET VAL ALA ALA VAL n/a n/a
112 5HGA - ARG PHE PRO LEU THR PHE GLY TRP n/a n/a
113 2X4O - LYS LEU THR PRO LEU CYS VAL THR LEU n/a n/a
114 5N6B - LEU LEU TRP ASN GLY PRO MET ALA VAL n/a n/a
115 1QR1 - ILE ILE SER ALA VAL VAL GLY ILE LEU n/a n/a
116 3O3B - GLU LEU ALA GIC 3AZ LEU THR VAL n/a n/a
117 5C0I - ARG GLN PHE GLY PRO ASP PHE PRO THR ILE n/a n/a
118 5N1Y - MET VAL TRP GLY PRO ASP PRO LEU TYR VAL n/a n/a
119 5GSD - SER SER CYS PRO LEU SER LYS n/a n/a
120 1I1Y - TYR LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
121 3FT3 ic50 = 44 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
122 2VLL - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
123 1T1Z - ALA LEU TYR ASN THR ALA ALA ALA LEU n/a n/a
124 3FQT - GLY LEU LEU GLY SER PRO VAL ARG ALA n/a n/a
125 3GSQ - ASN LEU VAL PRO SER VAL ALA THR VAL n/a n/a
126 4NQX - CYS THR GLU LEU LYS LEU ASN ASP TYR n/a n/a
127 3VXN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
128 5C0J - ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA n/a n/a
129 1DUZ - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
130 3H7B Kd = 41 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
131 3WL9 - ASN TYR THR PRO GLY PRO GLY ILE ARG PHE n/a n/a
132 4JFP - GLU LEU ALA ALA ILE GLY ILE LEU THR VAL n/a n/a
133 3FQW - ARG VAL ALA SER PRO THR SER GLY VAL n/a n/a
134 1TVB - ILE THR ASP GLN VAL PRO PHE SER VAL n/a n/a
135 1T1W - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
136 5C0F - ARG GLN TRP GLY PRO ASP PRO ALA ALA VAL n/a n/a
137 3MYJ - TYR MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
138 4WJ5 ic50 = 0.51 uM GRN NVA ALA GLY ILE GLY ILE LEU THR LPH n/a n/a
139 1Q94 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
140 3H9H Kd = 5.4 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
141 3O3E - BAL LEU ALA TIG 3AZ LEU THR VAL n/a n/a
142 4I4W - ILE LEU ALA LYS PHE LEU HIS ARG LEU n/a n/a
143 2X4R - ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
144 4HWZ - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
145 3PWJ Kd = 70 uM LEU LEU TYR GLY PHE VAL ASN TYR VAL n/a n/a
146 3FQN - TYR LEU ASP SER GLY ILE HIS SER GLY ALA n/a n/a
147 3BHB ic50 = 3.4 nM LYS MET ASP SEP PHE LEU ASP MET GLN LEU n/a n/a
148 1S9W - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
149 5C0G - TYR LEU GLY GLY PRO ASP PHE PRO THR ILE n/a n/a
150 4HX1 - SER VAL TYR ASP PHE PHE VAL TRP LEU n/a n/a
151 3MGO - ARG LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
152 1I7R - PHE ALA PRO GLY PHE PHE PRO TYR LEU n/a n/a
153 1X7Q - LYS THR PHE PRO PRO THR GLU PRO LYS n/a n/a
154 3WLB - ASN TYR THR PRO GLY PRO GLY THR ARG PHE n/a n/a
155 3RL2 - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
156 2GUO - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
157 4JFQ - GLU LEU ALA GLY ILE GLY ILE ALA THR VAL n/a n/a
158 5EU4 - TYR LEU ALA PRO GLY PRO VAL THR ALA n/a n/a
159 1I7U - ALA LEU TRP GLY PHE VAL PRO VAL LEU n/a n/a
160 5C0D - ALA GLN TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
161 3GSO Kd = 27.7 uM ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
162 3HPJ - ARG MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
163 3KLA Kd = 31.1 uM SER LEU LEU MET TRP ILE THR GLN LEU n/a n/a
164 4K7F - VAL CYS TRP GLY GLU LEU MET ASN LEU n/a n/a
165 2V2W Kd = 2.2 uM SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
166 5SWQ - CYS VAL ASN GLY SER CYS PHE THR VAL n/a n/a
167 3I6L - GLN PHE LYS ASP ASN VAL ILE LEU LEU n/a n/a
168 1QVO - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
169 2GIT - LEU LEU PHE GLY LYS PRO VAL TYR VAL n/a n/a
170 5EU5 - TYR LEU GLU PRO ALA PRO VAL THR ALA n/a n/a
171 2X70 - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
172 2GTZ - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
173 3OXR - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
174 1T1Y - SER LEU TYR ASN VAL VAL ALA THR LEU n/a n/a
175 1EEZ - ILE LEU SER ALA LEU VAL GLY ILE LEU n/a n/a
176 1TVH - ILE MET ASP GLN VAL PRO PHE SER VAL n/a n/a
177 3REW Kd = 28.8 uM CYS LEU GLY GLY LEU LEU THR MET VAL n/a n/a
178 5MEQ Kd = 28 uM ILE LEU ALA LYS PHE LEU HIS THR LEU n/a n/a
179 3I6G - GLY LEU MET TRP LEU SER TYR PHE VAL n/a n/a
180 5NMH - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
181 2C7U Kd = 100 nM SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
182 1EEY - ILE LEU SER ALA LEU VAL GLY ILE VAL n/a n/a
183 1HHJ - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
184 5HGB - ARG TYR PRO LEU THR PHE GLY TRP n/a n/a
185 2GTW - LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
186 3GSV Kd = 57.5 uM ASN LEU VAL PRO GLN VAL ALA THR VAL n/a n/a
187 3D25 ic50 = 22 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
188 5EU3 - TYR LEU GLU PRO GLY PRO VAL THR ALA n/a n/a
189 3BH9 ic50 = 116.9 nM ARG THR TYR SEP GLY PRO MET ASN LYS VAL n/a n/a
190 3OXS - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
191 2V2X Kd = 5.2 uM SER LEU PHE ASN THR VAL ALA THR LEU n/a n/a
192 4JFO Kd = 140 uM ALA LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
193 5HHP - GLY ILE LEU GLU PHE VAL PHE THR LEU n/a n/a
194 4GKS - PHE LEU THR GLY ILE GLY ILE ILE THR VAL n/a n/a
195 1T20 - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
196 3GIV - SER LEU PHE ASN THR VAL ALA THR LEU TYR n/a n/a
197 3VXP - ARG TYR PRO LEU THR LEU GLY TRP CYS PHE n/a n/a
198 3PWL Kd = 140 uM LEU GLY TYR GLY PHE VAL ASN TYR ILE n/a n/a
199 5NMK - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
200 5C0E - TYR GLN PHE GLY PRO ASP PHE PRO ILE ALA n/a n/a
201 3UTQ - ALA LEU TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
202 4F7P - PHE TYR ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
203 3RL1 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
204 5HGH - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
205 3QFD Kd = 68 uM ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
206 3O3A - BAL LEU ALA GIC 3AZ LEU THR VAL n/a n/a
207 2X4N - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
208 4F7T - ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
209 5GRD - SER SER CYS SER SER CYS PRO LEU SER LYS n/a n/a
210 5MEO Kd = 1 uM ILE LEU GLY LYS PHE LEU HIS ARG LEU n/a n/a
211 3GSU Kd = 58.2 uM ASN LEU VAL PRO THR VAL ALA THR VAL n/a n/a
212 5HGD - ARG PHE PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
213 3IXA Kd = 9.8 uM LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
214 3FT2 ic50 = 44 nM VAL LEU CIR ASP ASP LEU LEU GLU ALA n/a n/a
215 2GT9 - GLU ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
216 5MER - ILE LEU ALA LYS PHE LEU HIS GLU LEU n/a n/a
217 5HHN - GLY ILE LEU GLY LEU VAL PHE THR LEU n/a n/a
218 2CLR - MET LEU LEU SER VAL PRO LEU LEU LEU GLY n/a n/a
219 1T22 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
220 1I4F - GLY VAL TYR ASP GLY ARG GLU HIS THR VAL n/a n/a
221 3NFN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
222 3FQU - GLY LEU LEU GLY SEP PRO VAL ARG ALA n/a n/a
223 1JF1 - GLU LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
224 1HHK - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
225 3BH8 ic50 = 11.2 nM ARG GLN ALA SEP ILE GLU LEU PRO SER MET n/a n/a
226 3BGM ic50 = 32.5 nM ARG GLN ALA SEP LEU SER ILE SER VAL n/a n/a
227 3O3D - GLU LEU ALA TIG 3AZ LEU THR VAL n/a n/a
228 3PWN Kd = 48 uM LEU LEU TYR GLY PHE VAL ASN TYR ILE n/a n/a
229 3MGT - LYS LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
230 3FQX - ARG VAL ALA SEP PRO THR SER GLY VAL n/a n/a
231 1S9Y - SER LEU LEU MET TRP ILE THR GLN SER n/a n/a
232 2AV7 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
233 1S8D - SER LEU ALA ASN THR VAL ALA THR LEU n/a n/a
234 4F7M - LEU TYR ALA SER PRO GLN LEU GLU GLY PHE n/a n/a
235 3OX8 - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
236 3GSX - ASN LEU VAL PRO MET VAL ALA VAL VAL n/a n/a
237 1T1X - SER LEU TYR LEU THR VAL ALA THR LEU n/a n/a
238 1DUY - LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
239 1S9X - SER LEU LEU MET TRP ILE THR GLN ALA n/a n/a
240 2X4P - MSE ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
241 3FT4 ic50 = 1171 nM VAL LEU ARG ASP ASP LEU LEU GLU ALA n/a n/a
242 1HHI - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
243 1JHT - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
244 2X4U - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
245 4NQV - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
246 5HHQ - GLY ILE TRP GLY PHE VAL PHE THR LEU n/a n/a
247 1T21 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
248 3BO8 - GLU ALA ASP PRO THR GLY HIS SER TYR n/a n/a
249 2AV1 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
250 3GSR Kd = 60.2 uM ASN LEU VAL PRO VAL VAL ALA THR VAL n/a n/a
251 1QEW - PHE LEU TRP GLY PRO ARG ALA LEU VAL n/a n/a
252 1HSB - ALA VAL ALA n/a n/a
253 2HN7 ic50 = 31 nM ALA ILE MET PRO ALA ARG PHE TYR PRO LYS n/a n/a
254 3FQR - TYR LEU ASP SEP GLY ILE HIS SER GLY ALA n/a n/a
255 5GRG - SER SER CYS SER SER CYS n/a n/a
256 2RFX - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
257 5VCL - ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
258 3VJ6 Kd = 17 uM ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
259 1WBZ - SER SER TYR ARG ARG PRO VAL GLY ILE n/a n/a
260 1VAD - SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
261 1FZM Kd = 20 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
262 4PV8 - ARG ABA PHE ILE PHE ALA ASN ILE n/a n/a
263 2ZSV - ARG ABA GLN ILE PHE ALA ASN ILE n/a n/a
264 2CLZ - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
265 1RK1 - SER GLU ILE GLU PHE ALA ARG LEU n/a n/a
266 3PAB Kd = 20 uM GLU ILE ILE ASN PHE GLU LYS LEU n/a n/a
267 1G7Q Kd = 877 nM SER ALA PRO ASP THR ARG PRO ALA n/a n/a
268 1FZO Kd = 13 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
269 4HS3 - ALA VAL TYR ASN PHE ALA THR MET n/a n/a
270 4PV9 - ARG ABA VAL ILE PHE ALA ASN ILE n/a n/a
271 1LEK Kd = 1.3 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
272 4PG9 - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
273 1NAN - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
274 2VAA - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
275 2VAB - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
276 2CLV - SER GLN TYR TYR TYR ASN SER LEU n/a n/a
277 1KJ3 - LYS VAL ILE THR PHE ILE ASP LEU n/a n/a
278 1RJY - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
279 1FZJ Kd = 8 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
280 1G7P Kd = 90 nM SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
281 1KPU - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
282 1T0N - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
283 3P9L Kd = 6 uM SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
284 1T0M - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
285 1FZK Kd = 4 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
286 1KPV - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
287 1OSZ - ARG GLY TYR LEU TYR GLN GLY LEU n/a n/a
288 1LK2 ic50 = 12 uM GLY ASN TYR SER PHE TYR ALA LEU n/a n/a
289 1LEG Kd = 11.1 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
290 1KBG - ARG GLY TYR VAL TYR ESC GLY LEU GAL GLA n/a n/a
291 4PGE - PHE ALA PRO GLY ASN TYR PRO ALA TRP n/a n/a
292 3P9M Kd = 10 uM SER ILE ILE GLY PHE GLU LYS LEU n/a n/a
293 1VAC - SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
294 3PWU - ILE PRO ALA TYR GLY VAL LEU THR ILE n/a n/a
295 3CC5 - LYS VAL PRO ARG ASN GLN ASP TRP LEU n/a n/a
296 5MZM - MET CYS PRO ARG MET THR ALA VAL MET n/a n/a
297 4L8B - ALA SER ASN GLU HIS MET GLU THR MET n/a n/a
298 3CPL - ALA SER ASN GLU ASN ALA GLU THR MET n/a n/a
299 1WBY - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
300 3CH1 - GLU GLY PRO ARG ASN GLN ASP TRP LEU n/a n/a
301 4HV8 - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
302 1WBX - SER GLN LEU LYS ASN ASN ALA LYS GLU ILE n/a n/a
303 1YN7 - SER SER LEU GLU ASN PHE ALA ALA TYR VAL n/a n/a
304 1YN6 - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
305 1JUF ic50 = 1400 nM SER SER VAL ILE GLY VAL TRP TYR LEU n/a n/a
306 1JPG - PHE GLN PRO GLN ASN GLY GLN PHE ILE n/a n/a
307 5E8O - MET ABA LEU ARG MET THR ALA VAL MET n/a n/a
308 1LD9 - TYR PRO ASN VAL ASN ILE HIS ASN PHE n/a n/a
309 5E8P - MET CYS LEU ARG NLE THR ALA VAL MET n/a n/a
310 1HOC - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
311 4HUX - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
312 4HUV - ALA SER ASN GLU ASN TRP GLU THR MET n/a n/a
313 1INQ ic50 = 539 nM SER SER VAL VAL GLY VAL TRP TYR LEU n/a n/a
314 2ZOK - ABA SER LEU TRP ASN GLY PRO HIS LEU n/a n/a
315 5E8N - MET CYS LEU ARG MET THR ALA VAL MET n/a n/a
316 4HUU - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
317 4L8D - ALA SER ASN GLU ASP MET GLU THR MET n/a n/a
318 1S7Q - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
319 1S7T - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
320 4ZFZ Kd = 2.5 uM GLY GLY ALA ILE SER MYR n/a n/a
321 3RWG ic50 = 2.8 nM MET HIS PRO ALA GLN THR SER GLN TRP n/a n/a
322 3RWI ic50 = 116 nM GLY SER HIS LEU GLU VAL GLN GLY TYR TRP n/a n/a
323 3RWC ic50 = 7.6 nM ILE ARG TYR PRO LYS THR PHE GLY TRP n/a n/a
324 3RWE ic50 = 43 nM PHE GLN TRP MET GLY TYR GLU LEU TRP n/a n/a
325 3FOM - ILE GLN GLN SER ILE GLU ARG ILE n/a n/a
326 3FON - VAL ASN ASP ILE PHE GLU ALA ILE n/a n/a
327 5GSV - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
328 4WDI Kd = 286 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY n/a n/a
329 5GSR - TYR TYR SER ILE ALA PRO HIS SER ILE n/a n/a
330 5GR7 - TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
331 4Z78 Kd = 113 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY PHE n/a n/a
332 4Z76 Kd = 13.6 uM LEU TYR LEU VAL CYS GLY GLU ARG VAL n/a n/a
333 5GSX - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
334 5GSB - LYS TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
335 3BZF - VAL MET ALA PRO ARG ALA LEU LEU LEU n/a n/a
336 6GH4 - ARG GLN PRO ALA LYS ALA PRO LEU LEU n/a n/a
337 6GH1 - ARG LEU PRO ALA LYS ALA PRO LEU LEU n/a n/a
338 3BZE - VAL MET ALA PRO ARG THR LEU PHE LEU n/a n/a
339 5H94 - LYS MET ASN THR GLN PHE THR ALA VAL n/a n/a
340 3QQ4 - ALA THR ALA ALA ALA THR GLU ALA TYR n/a n/a
341 5XS3 - VAL ARG SER ARG ARG CYS LEU ARG LEU n/a n/a
342 3ECB - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
343 5WEU Kd = 0.19 mM ARG GLY PRO GLY CYS ALA PHE VAL THR ILE n/a n/a
344 3E6F - ILE GLY PRO GLY ARG ALA PHE TYR ALA n/a n/a
345 5KD7 - ILE GLY PRO GLY ARG ALA PHE TYR VAL n/a n/a
346 3E6H - ILE GLY PRO GLY ARG ALA PHE TYR THR ILE n/a n/a
347 5T7G - ILE GLY PRO GLY ARG ALA PHE TYR THR n/a n/a
348 1MHC - FME TYR PHE ILE ASN ILE LEU THR LEU n/a n/a
349 1ZT1 - PHE GLU ALA ASN GLY ASN LEU ILE n/a n/a
350 1K8D - ILE LEU MET GLU HIS ILE HIS LYS LEU n/a n/a
351 1KJM - ALA GLN PHE SER ALA SER ALA SER ARG n/a n/a
352 5J6H - NCA C6 H6 N2 O c1cc(cnc1)....
353 1KJV - ASN PRO ARG ALA MET GLN ALA LEU LEU n/a n/a
354 1YDP - ARG ILE ILE PRO ARG HIS LEU GLN LEU n/a n/a
355 3KYN - LYS GLY PRO PRO ALA ALA LEU THR LEU n/a n/a
356 3KYO - LYS LEU PRO ALA GLN PHE TYR ILE LEU n/a n/a
357 1S7X - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
358 1S7U - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
359 1S7V - LYS ALA VAL TYR ASN LEU ALA THR MET n/a n/a
360 1S7W - LYS ALA LEU TYR ASN PHE ALA THR MET n/a n/a
50% Homology Family (366)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 42 families.
1 4QRT - GLU LEU ASN ARG LYS MET ILE TYR MET n/a n/a
2 3KPN - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
3 4U1H - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
4 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
5 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
6 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
7 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
8 5IND - GLN ALA SER GLN ASP VAL LYS ASN TRP n/a n/a
9 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
10 5V5L - THR SER THR LEU GLN GLU GLN ILE GLY TRP n/a n/a
11 5DEG - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
12 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
13 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
14 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
15 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
16 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
17 5WMP - THR PRO ARG VAL THR GLY GLY GLY ALA MET n/a n/a
18 5DEF - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
19 4U1M - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
20 5IM7 - GLN ALA SER GLN GLU VAL LYS ASN TRP n/a n/a
21 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
22 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
23 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
24 5WMR - GLN ILE LYS VAL ARG VAL ASP MET VAL n/a n/a
25 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
26 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
27 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
28 5EO0 - ARG PRO MET THR PHE LYS GLY ALA LEU n/a n/a
29 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
30 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
31 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
32 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
33 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
34 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
35 6BXP - ARG VAL LYS GLU LYS TYR GLN HIS LEU KYN n/a n/a
36 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
37 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
38 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
39 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
40 4U1N - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
41 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
42 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
43 5WMN - SER PRO ILE VAL PRO SER PHE ASP MET n/a n/a
44 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
45 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
46 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
47 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
48 4U1S - PHE PRO ARG PRO TRP LEU HIS GLY LEU n/a n/a
49 4U1K - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
50 5U98 Kd = 0.2 nM VAL THR THR ASP ILE GLN VAL LYS VAL n/a n/a
51 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
52 4XXC - ASP GLU LEU GLU ILE LYS ALA TYR n/a n/a
53 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
54 4QRQ Kd = 2.48 uM HIS SER LYS LYS LYS CYS ASP GLU LEU n/a n/a
55 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
56 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
57 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
58 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
59 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
60 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
61 5WMO - ARG PRO PRO ILE PHE ILE ARG ARG LEU n/a n/a
62 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
63 4U1L - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
64 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
65 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
66 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
67 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
68 5W67 - VAL ARG SER ARG ARG ABA LEU ARG LEU n/a n/a
69 5EO1 - ARG PRO MET THR TYR LYS GLY ALA LEU n/a n/a
70 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
71 5TXS - ALA GLN ASP ILE TYR ARG ALA SER TYR n/a n/a
72 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
73 5WMQ - GLU LEU ARG SER ARG TYR TRP ALA ILE n/a n/a
74 4QRS - GLU LEU LYS ARG LYS MET ILE TYR MET n/a n/a
75 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
76 4U1I - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
77 6BXQ - ARG VAL LYS GLU LYS TYR GLN HIS LEU TRP n/a n/a
78 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
79 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
80 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
81 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
82 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
83 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
84 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
85 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
86 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
87 4U1J - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
88 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
89 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
90 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
91 5VGD - SER ALA GLU PRO VAL PRO LEU GLN LEU n/a n/a
92 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
93 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
94 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
95 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
96 5T6W - SER SER THR ARG GLY ILE SER GLN LEU TRP n/a n/a
97 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
98 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
99 4QRU - GLU LEU ARG ARG LYS MET MET TYR MET n/a n/a
100 5W6A - ALA ARG THR GLU LEU TYR ARG SER LEU n/a n/a
101 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
102 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
103 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
104 5T6X - THR SER THR THR SER VAL ALA SER SER TRP n/a n/a
105 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
106 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
107 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
108 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
109 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
110 1B0G - ALA LEU TRP GLY PHE PHE PRO VAL LEU n/a n/a
111 3GSW - ASN LEU VAL PRO MET VAL ALA ALA VAL n/a n/a
112 5HGA - ARG PHE PRO LEU THR PHE GLY TRP n/a n/a
113 2X4O - LYS LEU THR PRO LEU CYS VAL THR LEU n/a n/a
114 5N6B - LEU LEU TRP ASN GLY PRO MET ALA VAL n/a n/a
115 1QR1 - ILE ILE SER ALA VAL VAL GLY ILE LEU n/a n/a
116 3O3B - GLU LEU ALA GIC 3AZ LEU THR VAL n/a n/a
117 5C0I - ARG GLN PHE GLY PRO ASP PHE PRO THR ILE n/a n/a
118 5N1Y - MET VAL TRP GLY PRO ASP PRO LEU TYR VAL n/a n/a
119 5GSD - SER SER CYS PRO LEU SER LYS n/a n/a
120 1I1Y - TYR LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
121 3FT3 ic50 = 44 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
122 2VLL - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
123 1T1Z - ALA LEU TYR ASN THR ALA ALA ALA LEU n/a n/a
124 3FQT - GLY LEU LEU GLY SER PRO VAL ARG ALA n/a n/a
125 3GSQ - ASN LEU VAL PRO SER VAL ALA THR VAL n/a n/a
126 4NQX - CYS THR GLU LEU LYS LEU ASN ASP TYR n/a n/a
127 3VXN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
128 5C0J - ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA n/a n/a
129 1DUZ - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
130 3H7B Kd = 41 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
131 3WL9 - ASN TYR THR PRO GLY PRO GLY ILE ARG PHE n/a n/a
132 4JFP - GLU LEU ALA ALA ILE GLY ILE LEU THR VAL n/a n/a
133 3FQW - ARG VAL ALA SER PRO THR SER GLY VAL n/a n/a
134 1TVB - ILE THR ASP GLN VAL PRO PHE SER VAL n/a n/a
135 1T1W - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
136 5C0F - ARG GLN TRP GLY PRO ASP PRO ALA ALA VAL n/a n/a
137 3MYJ - TYR MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
138 4WJ5 ic50 = 0.51 uM GRN NVA ALA GLY ILE GLY ILE LEU THR LPH n/a n/a
139 1Q94 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
140 3H9H Kd = 5.4 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
141 3O3E - BAL LEU ALA TIG 3AZ LEU THR VAL n/a n/a
142 4I4W - ILE LEU ALA LYS PHE LEU HIS ARG LEU n/a n/a
143 2X4R - ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
144 4HWZ - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
145 3PWJ Kd = 70 uM LEU LEU TYR GLY PHE VAL ASN TYR VAL n/a n/a
146 3FQN - TYR LEU ASP SER GLY ILE HIS SER GLY ALA n/a n/a
147 3BHB ic50 = 3.4 nM LYS MET ASP SEP PHE LEU ASP MET GLN LEU n/a n/a
148 1S9W - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
149 5C0G - TYR LEU GLY GLY PRO ASP PHE PRO THR ILE n/a n/a
150 4HX1 - SER VAL TYR ASP PHE PHE VAL TRP LEU n/a n/a
151 3MGO - ARG LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
152 1I7R - PHE ALA PRO GLY PHE PHE PRO TYR LEU n/a n/a
153 1X7Q - LYS THR PHE PRO PRO THR GLU PRO LYS n/a n/a
154 3WLB - ASN TYR THR PRO GLY PRO GLY THR ARG PHE n/a n/a
155 3RL2 - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
156 2GUO - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
157 4JFQ - GLU LEU ALA GLY ILE GLY ILE ALA THR VAL n/a n/a
158 5EU4 - TYR LEU ALA PRO GLY PRO VAL THR ALA n/a n/a
159 1I7U - ALA LEU TRP GLY PHE VAL PRO VAL LEU n/a n/a
160 5C0D - ALA GLN TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
161 3GSO Kd = 27.7 uM ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
162 3HPJ - ARG MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
163 3KLA Kd = 31.1 uM SER LEU LEU MET TRP ILE THR GLN LEU n/a n/a
164 4K7F - VAL CYS TRP GLY GLU LEU MET ASN LEU n/a n/a
165 2V2W Kd = 2.2 uM SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
166 5SWQ - CYS VAL ASN GLY SER CYS PHE THR VAL n/a n/a
167 3I6L - GLN PHE LYS ASP ASN VAL ILE LEU LEU n/a n/a
168 1QVO - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
169 2GIT - LEU LEU PHE GLY LYS PRO VAL TYR VAL n/a n/a
170 5EU5 - TYR LEU GLU PRO ALA PRO VAL THR ALA n/a n/a
171 2X70 - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
172 2GTZ - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
173 3OXR - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
174 1T1Y - SER LEU TYR ASN VAL VAL ALA THR LEU n/a n/a
175 1EEZ - ILE LEU SER ALA LEU VAL GLY ILE LEU n/a n/a
176 1TVH - ILE MET ASP GLN VAL PRO PHE SER VAL n/a n/a
177 3REW Kd = 28.8 uM CYS LEU GLY GLY LEU LEU THR MET VAL n/a n/a
178 5MEQ Kd = 28 uM ILE LEU ALA LYS PHE LEU HIS THR LEU n/a n/a
179 3I6G - GLY LEU MET TRP LEU SER TYR PHE VAL n/a n/a
180 5NMH - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
181 2C7U Kd = 100 nM SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
182 1EEY - ILE LEU SER ALA LEU VAL GLY ILE VAL n/a n/a
183 1HHJ - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
184 5HGB - ARG TYR PRO LEU THR PHE GLY TRP n/a n/a
185 2GTW - LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
186 3GSV Kd = 57.5 uM ASN LEU VAL PRO GLN VAL ALA THR VAL n/a n/a
187 3D25 ic50 = 22 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
188 5EU3 - TYR LEU GLU PRO GLY PRO VAL THR ALA n/a n/a
189 3BH9 ic50 = 116.9 nM ARG THR TYR SEP GLY PRO MET ASN LYS VAL n/a n/a
190 3OXS - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
191 2V2X Kd = 5.2 uM SER LEU PHE ASN THR VAL ALA THR LEU n/a n/a
192 4JFO Kd = 140 uM ALA LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
193 5HHP - GLY ILE LEU GLU PHE VAL PHE THR LEU n/a n/a
194 4GKS - PHE LEU THR GLY ILE GLY ILE ILE THR VAL n/a n/a
195 1T20 - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
196 3GIV - SER LEU PHE ASN THR VAL ALA THR LEU TYR n/a n/a
197 3VXP - ARG TYR PRO LEU THR LEU GLY TRP CYS PHE n/a n/a
198 3PWL Kd = 140 uM LEU GLY TYR GLY PHE VAL ASN TYR ILE n/a n/a
199 5NMK - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
200 5C0E - TYR GLN PHE GLY PRO ASP PHE PRO ILE ALA n/a n/a
201 3UTQ - ALA LEU TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
202 4F7P - PHE TYR ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
203 3RL1 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
204 5HGH - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
205 3QFD Kd = 68 uM ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
206 3O3A - BAL LEU ALA GIC 3AZ LEU THR VAL n/a n/a
207 2X4N - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
208 4F7T - ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
209 5GRD - SER SER CYS SER SER CYS PRO LEU SER LYS n/a n/a
210 5MEO Kd = 1 uM ILE LEU GLY LYS PHE LEU HIS ARG LEU n/a n/a
211 3GSU Kd = 58.2 uM ASN LEU VAL PRO THR VAL ALA THR VAL n/a n/a
212 5HGD - ARG PHE PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
213 3IXA Kd = 9.8 uM LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
214 3FT2 ic50 = 44 nM VAL LEU CIR ASP ASP LEU LEU GLU ALA n/a n/a
215 2GT9 - GLU ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
216 5MER - ILE LEU ALA LYS PHE LEU HIS GLU LEU n/a n/a
217 5HHN - GLY ILE LEU GLY LEU VAL PHE THR LEU n/a n/a
218 2CLR - MET LEU LEU SER VAL PRO LEU LEU LEU GLY n/a n/a
219 1T22 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
220 1I4F - GLY VAL TYR ASP GLY ARG GLU HIS THR VAL n/a n/a
221 3NFN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
222 3FQU - GLY LEU LEU GLY SEP PRO VAL ARG ALA n/a n/a
223 1JF1 - GLU LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
224 1HHK - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
225 3BH8 ic50 = 11.2 nM ARG GLN ALA SEP ILE GLU LEU PRO SER MET n/a n/a
226 3BGM ic50 = 32.5 nM ARG GLN ALA SEP LEU SER ILE SER VAL n/a n/a
227 3O3D - GLU LEU ALA TIG 3AZ LEU THR VAL n/a n/a
228 3PWN Kd = 48 uM LEU LEU TYR GLY PHE VAL ASN TYR ILE n/a n/a
229 3MGT - LYS LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
230 3FQX - ARG VAL ALA SEP PRO THR SER GLY VAL n/a n/a
231 1S9Y - SER LEU LEU MET TRP ILE THR GLN SER n/a n/a
232 2AV7 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
233 1S8D - SER LEU ALA ASN THR VAL ALA THR LEU n/a n/a
234 4F7M - LEU TYR ALA SER PRO GLN LEU GLU GLY PHE n/a n/a
235 3OX8 - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
236 3GSX - ASN LEU VAL PRO MET VAL ALA VAL VAL n/a n/a
237 1T1X - SER LEU TYR LEU THR VAL ALA THR LEU n/a n/a
238 1DUY - LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
239 1S9X - SER LEU LEU MET TRP ILE THR GLN ALA n/a n/a
240 2X4P - MSE ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
241 3FT4 ic50 = 1171 nM VAL LEU ARG ASP ASP LEU LEU GLU ALA n/a n/a
242 1HHI - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
243 1JHT - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
244 2X4U - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
245 4NQV - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
246 5HHQ - GLY ILE TRP GLY PHE VAL PHE THR LEU n/a n/a
247 1T21 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
248 3BO8 - GLU ALA ASP PRO THR GLY HIS SER TYR n/a n/a
249 2AV1 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
250 3GSR Kd = 60.2 uM ASN LEU VAL PRO VAL VAL ALA THR VAL n/a n/a
251 1QEW - PHE LEU TRP GLY PRO ARG ALA LEU VAL n/a n/a
252 1HSB - ALA VAL ALA n/a n/a
253 2HN7 ic50 = 31 nM ALA ILE MET PRO ALA ARG PHE TYR PRO LYS n/a n/a
254 3FQR - TYR LEU ASP SEP GLY ILE HIS SER GLY ALA n/a n/a
255 5GRG - SER SER CYS SER SER CYS n/a n/a
256 2RFX - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
257 5VCL - ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
258 3VJ6 Kd = 17 uM ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
259 1WBZ - SER SER TYR ARG ARG PRO VAL GLY ILE n/a n/a
260 1VAD - SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
261 1FZM Kd = 20 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
262 4PV8 - ARG ABA PHE ILE PHE ALA ASN ILE n/a n/a
263 2ZSV - ARG ABA GLN ILE PHE ALA ASN ILE n/a n/a
264 2CLZ - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
265 1RK1 - SER GLU ILE GLU PHE ALA ARG LEU n/a n/a
266 3PAB Kd = 20 uM GLU ILE ILE ASN PHE GLU LYS LEU n/a n/a
267 1G7Q Kd = 877 nM SER ALA PRO ASP THR ARG PRO ALA n/a n/a
268 1FZO Kd = 13 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
269 4HS3 - ALA VAL TYR ASN PHE ALA THR MET n/a n/a
270 4PV9 - ARG ABA VAL ILE PHE ALA ASN ILE n/a n/a
271 1LEK Kd = 1.3 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
272 4PG9 - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
273 1NAN - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
274 2VAA - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
275 2VAB - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
276 2CLV - SER GLN TYR TYR TYR ASN SER LEU n/a n/a
277 1KJ3 - LYS VAL ILE THR PHE ILE ASP LEU n/a n/a
278 1RJY - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
279 1FZJ Kd = 8 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
280 1G7P Kd = 90 nM SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
281 1KPU - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
282 1T0N - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
283 3P9L Kd = 6 uM SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
284 1T0M - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
285 1FZK Kd = 4 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
286 1KPV - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
287 1OSZ - ARG GLY TYR LEU TYR GLN GLY LEU n/a n/a
288 1LK2 ic50 = 12 uM GLY ASN TYR SER PHE TYR ALA LEU n/a n/a
289 1LEG Kd = 11.1 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
290 1KBG - ARG GLY TYR VAL TYR ESC GLY LEU GAL GLA n/a n/a
291 4PGE - PHE ALA PRO GLY ASN TYR PRO ALA TRP n/a n/a
292 3P9M Kd = 10 uM SER ILE ILE GLY PHE GLU LYS LEU n/a n/a
293 1VAC - SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
294 3PWU - ILE PRO ALA TYR GLY VAL LEU THR ILE n/a n/a
295 3CC5 - LYS VAL PRO ARG ASN GLN ASP TRP LEU n/a n/a
296 5MZM - MET CYS PRO ARG MET THR ALA VAL MET n/a n/a
297 4L8B - ALA SER ASN GLU HIS MET GLU THR MET n/a n/a
298 3CPL - ALA SER ASN GLU ASN ALA GLU THR MET n/a n/a
299 1WBY - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
300 3CH1 - GLU GLY PRO ARG ASN GLN ASP TRP LEU n/a n/a
301 4HV8 - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
302 1WBX - SER GLN LEU LYS ASN ASN ALA LYS GLU ILE n/a n/a
303 1YN7 - SER SER LEU GLU ASN PHE ALA ALA TYR VAL n/a n/a
304 1YN6 - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
305 1JUF ic50 = 1400 nM SER SER VAL ILE GLY VAL TRP TYR LEU n/a n/a
306 1JPG - PHE GLN PRO GLN ASN GLY GLN PHE ILE n/a n/a
307 5E8O - MET ABA LEU ARG MET THR ALA VAL MET n/a n/a
308 1LD9 - TYR PRO ASN VAL ASN ILE HIS ASN PHE n/a n/a
309 5E8P - MET CYS LEU ARG NLE THR ALA VAL MET n/a n/a
310 1HOC - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
311 4HUX - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
312 4HUV - ALA SER ASN GLU ASN TRP GLU THR MET n/a n/a
313 1INQ ic50 = 539 nM SER SER VAL VAL GLY VAL TRP TYR LEU n/a n/a
314 2ZOK - ABA SER LEU TRP ASN GLY PRO HIS LEU n/a n/a
315 5E8N - MET CYS LEU ARG MET THR ALA VAL MET n/a n/a
316 4HUU - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
317 4L8D - ALA SER ASN GLU ASP MET GLU THR MET n/a n/a
318 1S7Q - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
319 1S7T - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
320 4G43 - ILE ASP TRP PHE GLU GLY LYS GLU n/a n/a
321 4E0R - ILE ASP TRP PHE ASP GLY LYS GLU n/a n/a
322 4G42 - ILE ASP TRP PHE ASP GLY LYS ASP n/a n/a
323 4ZFZ Kd = 2.5 uM GLY GLY ALA ILE SER MYR n/a n/a
324 4CVZ - TYR GLU LEU ASP GLU LYS PHE ASP ARG LEU n/a n/a
325 3RWG ic50 = 2.8 nM MET HIS PRO ALA GLN THR SER GLN TRP n/a n/a
326 3RWI ic50 = 116 nM GLY SER HIS LEU GLU VAL GLN GLY TYR TRP n/a n/a
327 3RWC ic50 = 7.6 nM ILE ARG TYR PRO LYS THR PHE GLY TRP n/a n/a
328 3RWE ic50 = 43 nM PHE GLN TRP MET GLY TYR GLU LEU TRP n/a n/a
329 1BII - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
330 3FOM - ILE GLN GLN SER ILE GLU ARG ILE n/a n/a
331 3FON - VAL ASN ASP ILE PHE GLU ALA ILE n/a n/a
332 5GSV - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
333 4WDI Kd = 286 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY n/a n/a
334 5GSR - TYR TYR SER ILE ALA PRO HIS SER ILE n/a n/a
335 5GR7 - TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
336 4Z78 Kd = 113 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY PHE n/a n/a
337 4Z76 Kd = 13.6 uM LEU TYR LEU VAL CYS GLY GLU ARG VAL n/a n/a
338 5GSX - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
339 5GSB - LYS TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
340 3BZF - VAL MET ALA PRO ARG ALA LEU LEU LEU n/a n/a
341 6GH4 - ARG GLN PRO ALA LYS ALA PRO LEU LEU n/a n/a
342 6GH1 - ARG LEU PRO ALA LYS ALA PRO LEU LEU n/a n/a
343 3BZE - VAL MET ALA PRO ARG THR LEU PHE LEU n/a n/a
344 5H94 - LYS MET ASN THR GLN PHE THR ALA VAL n/a n/a
345 3QQ4 - ALA THR ALA ALA ALA THR GLU ALA TYR n/a n/a
346 5XS3 - VAL ARG SER ARG ARG CYS LEU ARG LEU n/a n/a
347 3ECB - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
348 5WEU Kd = 0.19 mM ARG GLY PRO GLY CYS ALA PHE VAL THR ILE n/a n/a
349 3E6F - ILE GLY PRO GLY ARG ALA PHE TYR ALA n/a n/a
350 5KD7 - ILE GLY PRO GLY ARG ALA PHE TYR VAL n/a n/a
351 3E6H - ILE GLY PRO GLY ARG ALA PHE TYR THR ILE n/a n/a
352 5T7G - ILE GLY PRO GLY ARG ALA PHE TYR THR n/a n/a
353 1MHC - FME TYR PHE ILE ASN ILE LEU THR LEU n/a n/a
354 1ZT1 - PHE GLU ALA ASN GLY ASN LEU ILE n/a n/a
355 1K8D - ILE LEU MET GLU HIS ILE HIS LYS LEU n/a n/a
356 1KJM - ALA GLN PHE SER ALA SER ALA SER ARG n/a n/a
357 5J6H - NCA C6 H6 N2 O c1cc(cnc1)....
358 1KJV - ASN PRO ARG ALA MET GLN ALA LEU LEU n/a n/a
359 1YDP - ARG ILE ILE PRO ARG HIS LEU GLN LEU n/a n/a
360 3KYN - LYS GLY PRO PRO ALA ALA LEU THR LEU n/a n/a
361 3KYO - LYS LEU PRO ALA GLN PHE TYR ILE LEU n/a n/a
362 1S7X - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
363 1S7U - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
364 1S7V - LYS ALA VAL TYR ASN LEU ALA THR MET n/a n/a
365 1S7W - LYS ALA LEU TYR ASN PHE ALA THR MET n/a n/a
366 1TMC - GLU VAL ALA PRO PRO GLU TYR HIS ARG LYS n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: LEU SER SER PRO VAL THR LYS SER PHE; Similar ligands found: 122
No: Ligand ECFP6 Tc MDL keys Tc
1 LEU SER SER PRO VAL THR LYS SER PHE 1 1
2 LEU PRO PHE GLU LYS SER THR VAL MET 0.586667 0.909091
3 ARG VAL SER PRO SER THR SER TYR THR PRO 0.560606 0.920635
4 LEU PRO PHE ASP LYS SER THR ILE MET 0.55414 0.895522
5 PHE PRO THR LYS ASP VAL ALA LEU 0.554054 0.951613
6 PRO LYS ARG PRO THR THR LEU ASN LEU PHE 0.546584 0.855072
7 GLY TYR GLU ASN PRO THR TYR LYS PHE PHE 0.544872 0.823529
8 VAL ORN LEU DPN PRO VAL ORN LEU DPN PRO 0.542857 0.84127
9 LEU ASN PHE PRO ILE SER PRO 0.521739 0.907692
10 LYS THR PHE PRO PRO THR GLU PRO LYS 0.52 0.904762
11 SER THR SEP PRO THR PHE ASN LYS 0.515924 0.84058
12 MAA LYS PRO PHE 0.515385 0.819672
13 LEU PRO PHE ASP LYS THR THR ILE MET 0.509554 0.880597
14 SER SER CYS PRO LEU SER LYS 0.507463 0.934426
15 ASN PHE ASP ASN PRO VAL TYR ARG LYS THR 0.497041 0.783784
16 LEU PRO SER PHE GLU THR ALA LEU 0.496644 0.951613
17 GLY GLN VAL PRO PHE SER LYS GLU GLU CYS 0.490323 0.90625
18 ALA ASN SER ARG PHE PRO THR SER ILE ILE 0.484472 0.828571
19 PHE LEU SER THR LYS 0.480916 0.8
20 GLN LEU SER PRO PHE PRO PHE ASP LEU 0.480263 0.892308
21 ARG SEP PRO VAL PHE SER 0.477419 0.777778
22 LEU PHE GLY TYR PRO VAL TYR VAL 0.476821 0.80597
23 ARG THR PHE SER PRO THR TYR GLY LEU 0.475309 0.808219
24 PHE TYR ALA PRO GLU PRO ILE THR SER LEU 0.475309 0.869565
25 GLY SER ASP PRO PHE LYS 0.47482 0.887097
26 GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.472393 0.852941
27 LYS LEU TYR GLN ASN PRO THR THR TYR ILE 0.472393 0.867647
28 PHE LEU PRO SER ASP PHE PHE PRO SER VAL 0.469799 0.907692
29 GLU GLU PRO THR VAL ILE LYS LYS TYR 0.46875 0.878788
30 ASN TRP SER HIS PRO GLN PHE GLU LYS 0.468531 0.818182
31 ILE THR ASP GLN VAL PRO PHE SER VAL 0.468354 0.936508
32 ARG ARG LEU PRO ILE PHE SER ARG LEU 0.468354 0.867647
33 LEU LEU PHE GLY PHE PRO VAL TYR VAL 0.467949 0.80597
34 LEU LEU PHE GLY TYR PRO VAL TYR VAL 0.467949 0.80597
35 LEU LEU PHE GLY LYS PRO VAL TYR VAL 0.465409 0.782609
36 ARG PRO MET THR PHE LYS GLY ALA LEU 0.465116 0.794521
37 LYS PRO VAL LEU ARG THR ALA 0.463087 0.835821
38 SER ASP ILE LEU PHE PRO ALA ASP SER 0.46 0.920635
39 GLY THR SER SER PRO SER ALA ASP 0.455882 0.870968
40 TYR LEU GLU PRO ALA PRO VAL THR ALA 0.45098 0.878788
41 SER TYR SEP PRO THR SEP PRO SEP TYR SER 0.449664 0.8
42 LEU PRO LYS MYK THR GLY GLY 0.448718 0.875
43 THR PRO PRO SER PRO PHE 0.447761 0.903226
44 LEU TYR ALA SER PRO GLN LEU GLU GLY PHE 0.446429 0.850746
45 ALA THR PRO PHE GLN GLU 0.445312 0.883333
46 LEU PRO PHE GLU ARG ALA THR VAL MET 0.444444 0.805556
47 ALA PHE ARG ILE PRO LEU THR ARG 0.44375 0.867647
48 ARG ARG ARG GLU ARG SER PRO THR ARG 0.443709 0.808824
49 PHE ASN PHE PRO GLN ILE THR 0.443709 0.848485
50 PRO THR SEP PRO SER TYR 0.443709 0.814286
51 LEU PRO PRO VAL VAL ALA LYS GLU ILE 0.441558 0.8125
52 ALA ASN SER ARG TRP PRO THR THR ARG LEU 0.441176 0.821918
53 PHE SER ALA PTR PRO SER GLU GLU ASP 0.440789 0.777778
54 GLU LEU PRO PRO VAL LYS ILE HIS CYS 0.439306 0.779412
55 LYS LEU THR PRO LEU CYS VAL THR LEU 0.439189 0.919355
56 1IP CYS PHE SER LYS PRO ARG 0.438272 0.788732
57 LYS GLN GLU PRO GLN GLU ILE ASP PHE 0.438272 0.84127
58 HIS HIS ALA SER PRO ARG LYS 0.434783 0.757143
59 GLU LYS PRO SER SER SER 0.432836 0.854839
60 TYR LEU LYS GLU PRO VAL HIS GLY VAL 0.432749 0.797101
61 TYR PRO SER LYS PRO ASP ASN PRO GLY GLU 0.432624 0.888889
62 DPN PRO DAR DTH NH2 0.432624 0.818182
63 GLU LEU PRO LEU VAL LYS ILE 0.432432 0.809524
64 ARG ILE PRO SER TYR ARG TYR ARG TYR 0.432258 0.819444
65 LEU PRO PHE ASP ARG THR THR ILE MET 0.431953 0.808219
66 TYR LEU GLU PRO GLY PRO VAL THR VAL 0.43125 0.907692
67 TYR LEU GLU PRO GLY PRO VAL THR ALA 0.43125 0.907692
68 ILE ARG TYR PRO LYS THR PHE GLY TRP 0.430851 0.75
69 LYS PRO PHE PTR VAL ASN VAL NH2 0.428571 0.756757
70 PBE PRO LYS THR SER GLY LYS ALA ALA 0.427586 0.852941
71 LYS LEU PRO ALA GLN PHE TYR ILE LEU 0.426035 0.808824
72 PHE ASN ARG PRO VAL 0.425676 0.768116
73 GLN VAL PRO LEU ARG PRO MET THR TYR LYS 0.425414 0.786667
74 SER SER GLY LYS VAL PRO LEU SER 0.424658 0.919355
75 ARG TYR PRO LEU THR PHE GLY TRP CYS PHE 0.424084 0.786667
76 ILE SER PRO ARG THR LEU ASP ALA TRP 0.423077 0.821918
77 ARG PRO GLY ASN PHE LEU GLN SER ARG LEU 0.422857 0.867647
78 HIS SER ILE THR TYR LEU LEU PRO VAL 0.422619 0.869565
79 VAL MET ALA PRO ARG THR LEU PHE LEU 0.422619 0.805556
80 ALA ASN SER ARG TYR PRO THR SER ILE ILE 0.421687 0.794521
81 SER THR GLY GLY VAL M3L LYS PRO HIS ARG 0.421622 0.776316
82 LYS PRO PHE PTR VAL ASN VAL GLU PHE 0.421053 0.746667
83 TYR PRO LYS ARG ILE ALA 0.420382 0.760563
84 ALA ILE MET PRO ALA ARG PHE TYR PRO LYS 0.41989 0.714286
85 ASP PHE GLU GLU ILE PRO GLU GLU TYS 0.419753 0.650602
86 ILE LEU LYS GLU PRO VAL HIS GLY VAL 0.419162 0.776119
87 PRO ALA PRO PHE ALA SER ALA 0.418919 0.903226
88 SER SER TYR ARG ARG PRO VAL GLY ILE 0.418182 0.84507
89 LEU VAL THR LEU VAL PHE VAL 0.41791 0.65
90 SER PRO ILE VAL PRO SER PHE ASP MET 0.417178 0.867647
91 TYR LEU ALA PRO GLY PRO VAL THR ALA 0.416667 0.893939
92 SER SER GLY LYS VAL PRO LEU 0.416667 0.903226
93 ARG LEU TYR GLN ASN PRO THR THR TYR ILE 0.416185 0.797297
94 LYS LEU LEU PHE 0.416 0.666667
95 LYS PRO ILE VAL GLN TYR ASP ASN PHE 0.415205 0.84058
96 LEU PRO PHE GLU ARG ALA THR ILE MET 0.414773 0.794521
97 ARG GLN PHE GLY PRO ASP PHE PRO THR ILE 0.414773 0.805556
98 SER PRO LYS ARG ILE ALA 0.413793 0.779412
99 ARG PRO MET THR TYR LYS GLY ALA LEU 0.413408 0.763158
100 ILE MET ASP GLN VAL PRO PHE SER VAL 0.413174 0.865672
101 SER MET PRO GLU LEU SER PRO VAL LEU 0.412162 0.850746
102 ARG PRO PRO GLY PHE SER PRO PHE ALA 0.412121 0.785714
103 GLY GLY CYS PHE SER LYS PRO LYS MYR 0.411765 0.863636
104 GLN VAL PRO SER ASP PRO TYR ASN TYR 0.411392 0.893939
105 LEU GLN ARG VAL LEU SEP ALA PRO PHE 0.411043 0.756757
106 THR PRO ARG ARG SER MLZ SER ALA 0.410959 0.814286
107 VAL SER GLN ASN TYR PRO ILE VAL GLN ASN 0.408805 0.893939
108 TYR SEP PRO THR SEP PRO SER 0.408163 0.802817
109 ARG PHE PRO LEU THR PHE GLY TRP 0.407821 0.794521
110 PHE LEU PRO HIS ALY TYR ASP VAL LYS LEU 0.407821 0.785714
111 ASN ASP LYS TYR GLU PRO PHE TRP GLU 0.407609 0.771429
112 VAL PRO LEU ARG PRO MET THR TYR 0.407186 0.797297
113 PKF 0.406452 0.710526
114 GLY LEU LEU GLY SER PRO VAL ARG ALA 0.406452 0.794118
115 PHE SER GLN HIS LYS THR SER TPO ILE 0.405882 0.716216
116 SER ILE TYR PHE TPO PRO GLU LEU TYR ASP 0.404494 0.786667
117 ARG PRO GLY ASN PHE LEU GLN SER ARG PRO 0.403409 0.842857
118 GLU PHE SER PRO 0.402985 0.83871
119 ASN GLY TYR GLU ASN PRO THR TYR LYS 0.402367 0.823529
120 TYR LEU GLY GLY PRO ASP PHE PRO THR ILE 0.402299 0.867647
121 ALA ASN SER ARG TRP PRO THR SER ALY ILE 0.4 0.776316
122 ARG VAL ALA SER PRO THR SER GLY VAL 0.4 0.823529
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2RFX; Ligand: LEU SER SER PRO VAL THR LYS SER PHE; Similar sites found with APoc: 20
This union binding pocket(no: 1) in the query (biounit: 2rfx.bio1) has 28 residues
No: Leader PDB Ligand Sequence Similarity
1 3KO0 TFP None
2 2HJR CIT 3.27273
3 3RV5 DXC 3.37079
4 3KYQ DPV 6.06061
5 1II7 DA 7.07071
6 3DZ6 PUT 7.46269
7 5N26 CPT 8.79121
8 2VKL MLT 8.88889
9 2BHW NEX 9.09091
10 2BCG GER 9.09091
11 3HLX PQQ 10.8527
12 3N7S 3N7 11.4583
13 2CIX CEJ 12.1212
14 3AIH BMA MAN MAN 12.9032
15 3O01 DXC 15.2727
16 4D1J DGJ 16.1616
17 1I0B PEL 16.7273
18 5LWY OLB 18.1818
19 5LX9 OLB 18.1818
20 4OGQ 7PH 23.5294
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