• Home
• Faq
• Browse
• Search
• Download
• Contact Us

Help?

Showing PDB: 2QPL

Navigate

Expand All | Collapse All

Receptor | Ligand | View in 3D

Family: 90% | 70% | 50% | site

External Links

|

Download

      Structure Biounit | Ligand Information

PDB           : .ZIP | .CSV

Family 90% : .ZIP | .CSV

Class         : .ZIP | .CSV

Receptor

PDB id	Resolution	Class	Description	Source	Keywords
2QPL	2.1 Å	EC: 2.4.2.1	CRYSTAL STRUCTURE OF CALF SPLEEN PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED TO A NOVEL PURINE ANALOGUE	BOS TAURUS	PURINE NUCLEOSIDE PHOSPHORYLASE ACETYLATION GLYCOSYLTRANSFERASE TRANSFERASE
Ref.:	CRYSTAL STRUCTURE OF CALF SPLEEN PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED TO A NOVEL PURINE ANALOGUE. FEBS LETT. V. 581 5082 2007

Ligand

Ligand	Chain:Residue	Validity	Ligand Warnings	Binding Data	NGL Viewer	Molecular Weight (Da)	Formula	SMILES
BTY	A:292;	Valid;	none;	ic50 = 18.9 uM		165.153	C6 H7 N5 O	Cc1cc...
MG	A:291;	Invalid;	none;	submit data		24.305	Mg	[Mg+2...
SO4	A:1;	Invalid;	none;	submit data		96.063	O4 S	[O-]S...

View in 3D viewer

90% Homology Family

Leader

PDB id	Resolution	Class	Description	Source	Keywords
1B8O	1.5 Å	EC: 2.4.2.1	PURINE NUCLEOSIDE PHOSPHORYLASE	BOS TAURUS	PENTOSYLTRANSFERASE PURINE NUCLEOSIDE PHOSPHORYLASE TRANSF
Ref.:	TRANSITION STATE STRUCTURE OF PURINE NUCLEOSIDE PHOSPHORYLASE AND PRINCIPLES OF ATOMIC MOTION IN EN CATALYSIS. BIOCHEMISTRY V. 40 853 2001

Members (17)

No:	PDB id	Binding Data	Representative ligand	Formula	Smiles
The Class containing this family consists of a total of 18 families.
1	1B8O	Ki = 23 pM	IMH	C11 H14 N4 O4	c1c(c2c([n....
2	1A9T	-	R1P	C5 H11 O8 P	C([C@@H]1[....
3	1VFN	Ki = 2.5 uM	HPA	C5 H4 N4 O	c1[nH]c2c(....
4	2QPL	ic50 = 18.9 uM	BTY	C6 H7 N5 O	Cc1cc2n(n1....
5	2AI1	ic50 = 300 nM	P1G	C12 H16 N5 O8 P	c1nc2c(n1[....
6	1B8N	Ki = 30 pM	IMG	C11 H15 N5 O4	c1c(c2c([n....
7	1A9S	-	NOS	C10 H12 N4 O5	c1nc2c(n1[....
8	2AI3	ic50 = 5000 nM	P2G	C11 H14 N5 O8 P	c1nc2c(n1[....
9	1LVU	Kd = 4.8 uM	9PP	C9 H13 N6 O4 P	C[C@@H](Cn....
10	1A9P	-	9DI	C11 H13 N3 O5	c1c(c2c([n....
11	2AI2	ic50 = 30 nM	P1D	C13 H16 N3 O8 P	c1c(c2c([n....
12	1V48	Ki = 16 nM	HA1	C10 H14 F2 N5 O4 P	c1nc2c(n1C....
13	1A9Q	-	HPA	C5 H4 N4 O	c1[nH]c2c(....
14	3FUC	Kd = 190 pM	9D9	C11 H15 F2 N4 O4 P	c1c(c2c([n....
15	1A9R	-	HPA	C5 H4 N4 O	c1[nH]c2c(....
16	1LV8	Kd = 3.5 uM	9PP	C9 H13 N6 O4 P	C[C@@H](Cn....
17	1FXU	-	GU7	C10 H16 N6 O3	c1nc2c(n1C....

70% Homology Family (30)

No:	PDB id	Binding Data	Representative ligand	Formula	Smiles
The Class containing this family consists of a total of 9 families.
1	2ON6	Ki = 172 nM	IMH	C11 H14 N4 O4	c1c(c2c([n....
2	2A0Y	Ki = 900 pM	DIH	C12 H17 N4 O3	c1c(c2c([n....
3	1RR6	-	IMH	C11 H14 N4 O4	c1c(c2c([n....
4	2A0X	Ki = 950 pM	DIH	C12 H17 N4 O3	c1c(c2c([n....
5	3GB9	-	A2F	C5 H4 F N5	c1[nH]c2c(....
6	1RT9	-	IMH	C11 H14 N4 O4	c1c(c2c([n....
7	5UGF	-	IM5	C12 H17 N5 O3	c1c(c2c([n....
8	3BGS	Ki = 380 pM	DIH	C12 H17 N4 O3	c1c(c2c([n....
9	1RSZ	-	DIH	C12 H17 N4 O3	c1c(c2c([n....
10	2A0W	Ki = 270 pM	DIH	C12 H17 N4 O3	c1c(c2c([n....
11	1B8O	Ki = 23 pM	IMH	C11 H14 N4 O4	c1c(c2c([n....
12	1A9T	-	R1P	C5 H11 O8 P	C([C@@H]1[....
13	1VFN	Ki = 2.5 uM	HPA	C5 H4 N4 O	c1[nH]c2c(....
14	2QPL	ic50 = 18.9 uM	BTY	C6 H7 N5 O	Cc1cc2n(n1....
15	2AI1	ic50 = 300 nM	P1G	C12 H16 N5 O8 P	c1nc2c(n1[....
16	1B8N	Ki = 30 pM	IMG	C11 H15 N5 O4	c1c(c2c([n....
17	1A9S	-	NOS	C10 H12 N4 O5	c1nc2c(n1[....
18	2AI3	ic50 = 5000 nM	P2G	C11 H14 N5 O8 P	c1nc2c(n1[....
19	1LVU	Kd = 4.8 uM	9PP	C9 H13 N6 O4 P	C[C@@H](Cn....
20	1A9P	-	9DI	C11 H13 N3 O5	c1c(c2c([n....
21	2AI2	ic50 = 30 nM	P1D	C13 H16 N3 O8 P	c1c(c2c([n....
22	1V48	Ki = 16 nM	HA1	C10 H14 F2 N5 O4 P	c1nc2c(n1C....
23	1A9Q	-	HPA	C5 H4 N4 O	c1[nH]c2c(....
24	3FUC	Kd = 190 pM	9D9	C11 H15 F2 N4 O4 P	c1c(c2c([n....
25	1A9R	-	HPA	C5 H4 N4 O	c1[nH]c2c(....
26	1LV8	Kd = 3.5 uM	9PP	C9 H13 N6 O4 P	C[C@@H](Cn....
27	1FXU	-	GU7	C10 H16 N6 O3	c1nc2c(n1C....
28	4EAR	-	IM5	C12 H17 N5 O3	c1c(c2c([n....
29	5ETJ	Kd = 66 pM	IM5	C12 H17 N5 O3	c1c(c2c([n....
30	4EB8	-	IM5	C12 H17 N5 O3	c1c(c2c([n....

50% Homology Family (44)

No:	PDB id	Binding Data	Representative ligand	Formula	Smiles
The Class containing this family consists of a total of 4 families.
1	2ON6	Ki = 172 nM	IMH	C11 H14 N4 O4	c1c(c2c([n....
2	2A0Y	Ki = 900 pM	DIH	C12 H17 N4 O3	c1c(c2c([n....
3	1RR6	-	IMH	C11 H14 N4 O4	c1c(c2c([n....
4	2A0X	Ki = 950 pM	DIH	C12 H17 N4 O3	c1c(c2c([n....
5	3GB9	-	A2F	C5 H4 F N5	c1[nH]c2c(....
6	1RT9	-	IMH	C11 H14 N4 O4	c1c(c2c([n....
7	5UGF	-	IM5	C12 H17 N5 O3	c1c(c2c([n....
8	3BGS	Ki = 380 pM	DIH	C12 H17 N4 O3	c1c(c2c([n....
9	1RSZ	-	DIH	C12 H17 N4 O3	c1c(c2c([n....
10	2A0W	Ki = 270 pM	DIH	C12 H17 N4 O3	c1c(c2c([n....
11	1B8O	Ki = 23 pM	IMH	C11 H14 N4 O4	c1c(c2c([n....
12	1A9T	-	R1P	C5 H11 O8 P	C([C@@H]1[....
13	1VFN	Ki = 2.5 uM	HPA	C5 H4 N4 O	c1[nH]c2c(....
14	2QPL	ic50 = 18.9 uM	BTY	C6 H7 N5 O	Cc1cc2n(n1....
15	2AI1	ic50 = 300 nM	P1G	C12 H16 N5 O8 P	c1nc2c(n1[....
16	1B8N	Ki = 30 pM	IMG	C11 H15 N5 O4	c1c(c2c([n....
17	1A9S	-	NOS	C10 H12 N4 O5	c1nc2c(n1[....
18	2AI3	ic50 = 5000 nM	P2G	C11 H14 N5 O8 P	c1nc2c(n1[....
19	1LVU	Kd = 4.8 uM	9PP	C9 H13 N6 O4 P	C[C@@H](Cn....
20	1A9P	-	9DI	C11 H13 N3 O5	c1c(c2c([n....
21	2AI2	ic50 = 30 nM	P1D	C13 H16 N3 O8 P	c1c(c2c([n....
22	1V48	Ki = 16 nM	HA1	C10 H14 F2 N5 O4 P	c1nc2c(n1C....
23	1A9Q	-	HPA	C5 H4 N4 O	c1[nH]c2c(....
24	3FUC	Kd = 190 pM	9D9	C11 H15 F2 N4 O4 P	c1c(c2c([n....
25	1A9R	-	HPA	C5 H4 N4 O	c1[nH]c2c(....
26	1LV8	Kd = 3.5 uM	9PP	C9 H13 N6 O4 P	C[C@@H](Cn....
27	1FXU	-	GU7	C10 H16 N6 O3	c1nc2c(n1C....
28	5IFK	-	HPA	C5 H4 N4 O	c1[nH]c2c(....
29	5TBT	-	CTN	C9 H13 N3 O5	C1=CN(C(=O....
30	5TBU	-	HPA	C5 H4 N4 O	c1[nH]c2c(....
31	5TBS	-	ADE	C5 H5 N5	c1[nH]c2c(....
32	4EAR	-	IM5	C12 H17 N5 O3	c1c(c2c([n....
33	5ETJ	Kd = 66 pM	IM5	C12 H17 N5 O3	c1c(c2c([n....
34	4EB8	-	IM5	C12 H17 N5 O3	c1c(c2c([n....
35	2P4S	Ki = 0.31 nM	DIH	C12 H17 N4 O3	c1c(c2c([n....
36	3FB1	-	R1P	C5 H11 O8 P	C([C@@H]1[....
37	3E9R	-	ADE	C5 H5 N5	c1[nH]c2c(....
38	3E0Q	-	JFD	C4 H4 Br N3 O2	C1(=C(NC(=....
39	3FNQ	-	HPA	C5 H4 N4 O	c1[nH]c2c(....
40	3FAZ	-	NOS	C10 H12 N4 O5	c1nc2c(n1[....
41	3IEX	-	GMP	C10 H13 N5 O5	c1nc2c(n1[....
42	3DJF	ic50 = 0.8 uM	BC3	C12 H11 N5 O	c1cc(cnc1)....
43	3F8W	-	ADN	C10 H13 N5 O4	c1nc(c2c(n....
44	1VMK	-	GUN	C5 H5 N5 O	c1[nH]c2c(....

Polypharmacology

Similar Ligands (2D)

Ligand no: 1; Ligand: BTY; Similar ligands found: 1

No:	Ligand	ECFP6 Tc	MDL keys Tc
1	BTY	1	1

Similar Ligands (3D)

Ligand no: 1; Ligand: BTY; Similar ligands found: 1185

No:	Ligand	Similarity coefficient
1	URC	1.0000
2	B55	1.0000
3	8TX	0.9990
4	XAZ	0.9983
5	75K	0.9980
6	5JQ	0.9932
7	5JL	0.9927
8	QBK	0.9920
9	8IG	0.9899
10	AZ8	0.9793
11	Q24	0.9792
12	9DG	0.9791
13	GUN	0.9785
14	AZA	0.9782
15	BGC	0.9777
16	M6N	0.9768
17	J9W	0.9765
18	M5K	0.9762
19	AJ2	0.9759
20	MUA	0.9755
21	CWM	0.9751
22	A2F	0.9745
23	XAN	0.9745
24	ES0	0.9744
25	PE0	0.9743
26	141	0.9736
27	IGA	0.9730
28	AQO	0.9727
29	MEW	0.9726
30	4HC	0.9726
31	2D0	0.9709
32	Q88	0.9705
33	B62	0.9705
34	AZG	0.9704
35	QX4	0.9704
36	6AP	0.9703
37	DX4	0.9698
38	0FO	0.9696
39	BOA	0.9695
40	1XM	0.9694
41	290	0.9690
42	YH7	0.9685
43	M1Q	0.9680
44	6GU	0.9673
45	XHP	0.9671
46	CFP	0.9670
47	OTW	0.9668
48	KT7	0.9663
49	ET2	0.9654
50	GLC	0.9636
51	MVN	0.9618
52	DQU	0.9616
53	4ME	0.9614
54	36R	0.9610
55	0CU	0.9602
56	44W	0.9593
57	5VM	0.9592
58	4M0	0.9584
59	HMH	0.9583
60	CLW	0.9581
61	6ME	0.9580
62	HH5	0.9579
63	VGD	0.9575
64	FA0	0.9573
65	2AK	0.9572
66	G3F	0.9570
67	5CU	0.9562
68	ES2	0.9555
69	0P6	0.9553
70	INE	0.9553
71	XQ0	0.9551
72	2EC	0.9549
73	H42	0.9542
74	1P8	0.9541
75	NOJ	0.9538
76	FBB	0.9536
77	BCP	0.9535
78	DOB	0.9532
79	RXA	0.9532
80	BHA	0.9530
81	AZ9	0.9525
82	EA1	0.9524
83	K2T	0.9523
84	5NU	0.9518
85	B53	0.9518
86	FYU	0.9516
87	GCS	0.9511
88	2AL	0.9510
89	5Q0	0.9506
90	BZX	0.9505
91	S76	0.9505
92	5IQ	0.9504
93	9MG	0.9503
94	CWS	0.9503
95	44V	0.9503
96	5SG	0.9502
97	O72	0.9501
98	0N7	0.9499
99	NQ	0.9498
100	HQY	0.9494
101	4YS	0.9492
102	1SQ	0.9492
103	1NP	0.9489
104	COU	0.9488
105	A7W	0.9485
106	JPZ	0.9483
107	5OB	0.9480
108	86J	0.9479
109	JBH	0.9476
110	RM1	0.9476
111	N5J	0.9475
112	VK3	0.9475
113	3F0	0.9475
114	4MU	0.9474
115	24W	0.9474
116	HQD	0.9473
117	VNL	0.9472
118	PH2	0.9472
119	14O	0.9471
120	DRL	0.9470
121	IV2	0.9470
122	NID	0.9470
123	ES1	0.9468
124	3DM	0.9467
125	1LQ	0.9466
126	1LM	0.9466
127	8S0	0.9463
128	FDB	0.9462
129	2HQ	0.9462
130	CWJ	0.9461
131	KUF	0.9461
132	7NI	0.9461
133	5H1	0.9460
134	2K4	0.9458
135	F60	0.9456
136	6VD	0.9456
137	APZ	0.9453
138	MRW	0.9452
139	MO8	0.9451
140	ODO	0.9451
141	7B4	0.9450
142	8CM	0.9449
143	ZZT	0.9448
144	3M0	0.9447
145	6RQ	0.9441
146	2AQ	0.9440
147	EV0	0.9438
148	6AI	0.9438
149	DIN	0.9436
150	4FS	0.9436
151	KIB	0.9433
152	5MB	0.9431
153	BEA	0.9431
154	97T	0.9431
155	OCH	0.9427
156	QPR	0.9427
157	4HM	0.9427
158	5RN	0.9425
159	PQ0	0.9424
160	03V	0.9420
161	5MI	0.9418
162	Q6T	0.9418
163	B57	0.9418
164	AX7	0.9415
165	I3A	0.9415
166	HJP	0.9415
167	209	0.9414
168	R8V	0.9414
169	JB5	0.9412
170	DBH	0.9412
171	3HA	0.9412
172	BZ3	0.9411
173	3ID	0.9410
174	1XN	0.9410
175	HMU	0.9410
176	42C	0.9408
177	D07	0.9408
178	4JQ	0.9408
179	5WY	0.9408
180	10L	0.9407
181	270	0.9407
182	ADZ	0.9405
183	8H8	0.9402
184	H33	0.9400
185	ISN	0.9397
186	8WO	0.9396
187	FE DB1	0.9395
188	2FQ	0.9393
189	ES5	0.9392
190	UNC	0.9392
191	ES9	0.9392
192	67N	0.9392
193	11S	0.9389
194	FOT	0.9386
195	HPA	0.9386
196	ADE	0.9384
197	261	0.9384
198	KIA	0.9382
199	2A7	0.9379
200	8WT	0.9377
201	7HQ	0.9375
202	92K	0.9374
203	AS3	0.9374
204	0W8	0.9374
205	MS9	0.9373
206	2MI	0.9371
207	M1A	0.9371
208	AHR	0.9371
209	AKH	0.9367
210	SYV	0.9366
211	PRF	0.9366
212	F0J	0.9364
213	JND	0.9364
214	4TU	0.9363
215	7W4	0.9363
216	4XH	0.9363
217	G3E	0.9363
218	PYQ	0.9362
219	M0W	0.9362
220	KKN	0.9361
221	5WV	0.9361
222	2A9	0.9360
223	JAE	0.9359
224	DMD	0.9358
225	HH8	0.9358
226	3Z8	0.9357
227	4CS	0.9356
228	B60	0.9355
229	680	0.9355
230	PRZ	0.9355
231	7VS	0.9353
232	TWO	0.9353
233	9DA	0.9352
234	FK1	0.9350
235	7WA	0.9349
236	12B	0.9348
237	ABV	0.9348
238	NDM	0.9347
239	LZM	0.9346
240	MQN	0.9345
241	9HX	0.9344
242	ORO	0.9344
243	5RO	0.9343
244	F9Y	0.9342
245	OXC	0.9341
246	H4N	0.9341
247	M1E	0.9339
248	J9T	0.9339
249	42A	0.9338
250	9R5	0.9338
251	5XC	0.9337
252	12Q	0.9337
253	ICO	0.9337
254	TTL	0.9337
255	IJZ	0.9336
256	94W	0.9335
257	TEP	0.9334
258	7HP	0.9333
259	23A	0.9333
260	XYP	0.9332
261	MAQ	0.9328
262	4AA	0.9327
263	MR1	0.9327
264	3PF	0.9327
265	HLZ	0.9325
266	V55	0.9322
267	5RG	0.9322
268	5QY	0.9322
269	Z5P	0.9321
270	KJH	0.9320
271	82I	0.9318
272	2ZQ	0.9317
273	ES7	0.9317
274	BDP	0.9316
275	PM6	0.9315
276	BTE	0.9314
277	9KT	0.9313
278	PDC	0.9313
279	4YO	0.9312
280	24B	0.9312
281	R9Y	0.9311
282	BP1	0.9310
283	20J	0.9307
284	8ZE	0.9307
285	SHA	0.9306
286	SVN	0.9304
287	2H5	0.9301
288	6NT	0.9299
289	Q71	0.9299
290	6MP	0.9294
291	KJY	0.9294
292	CLZ	0.9293
293	8NX	0.9293
294	7W1	0.9288
295	ES4	0.9287
296	D48	0.9287
297	DHK	0.9287
298	LXC	0.9287
299	SAL	0.9286
300	JTH	0.9286
301	8GC	0.9286
302	M1H	0.9284
303	PXM	0.9283
304	AW5	0.9282
305	GAB	0.9282
306	UAN	0.9282
307	9EW	0.9280
308	5QX	0.9280
309	BE2	0.9280
310	34D	0.9279
311	KJU	0.9279
312	TH7	0.9279
313	7ZE	0.9278
314	5HN	0.9277
315	3HB	0.9276
316	DOR	0.9276
317	FDR	0.9276
318	CTL	0.9275
319	C2U	0.9274
320	3NT	0.9273
321	3MG	0.9273
322	XIY	0.9272
323	1M2	0.9271
324	SE2	0.9270
325	3MB	0.9269
326	2ZM	0.9268
327	UEG	0.9267
328	7MU	0.9266
329	SWA	0.9266
330	8NY	0.9263
331	OVM	0.9263
332	SOE	0.9263
333	GXY	0.9261
334	HQT	0.9261
335	6M9	0.9260
336	4JT	0.9258
337	E7Z	0.9257
338	JBE	0.9257
339	0RW	0.9256
340	FP1	0.9256
341	3NY	0.9255
342	NSP	0.9255
343	52C	0.9255
344	N8Y	0.9254
345	NMJ	0.9254
346	3AB	0.9253
347	AX3	0.9252
348	2FG	0.9252
349	SXS	0.9250
350	HHA	0.9250
351	GDE	0.9250
352	GAL	0.9250
353	N2I	0.9250
354	0TU	0.9247
355	4SV	0.9243
356	1P7	0.9242
357	2HU	0.9242
358	MT0	0.9241
359	5NI	0.9241
360	2F6	0.9241
361	J5I	0.9240
362	PXL	0.9239
363	7ME	0.9239
364	4M4	0.9234
365	F81	0.9233
366	AJV	0.9233
367	GM7	0.9232
368	OVV	0.9230
369	6M4	0.9227
370	XQG	0.9226
371	HHR	0.9226
372	KYA	0.9226
373	QUZ	0.9225
374	92P	0.9225
375	GJS	0.9224
376	WCE	0.9224
377	EQT	0.9222
378	B5D	0.9222
379	J6W	0.9221
380	CTS	0.9220
381	K3Q	0.9219
382	F05	0.9218
383	4Z4	0.9217
384	G6D	0.9217
385	495	0.9216
386	D1X	0.9216
387	9FL	0.9215
388	M2K	0.9215
389	HIS	0.9215
390	GZ8	0.9214
391	TGX	0.9211
392	3IT	0.9211
393	HZQ	0.9210
394	4XR	0.9210
395	QAT	0.9209
396	GIO	0.9208
397	3WA	0.9207
398	0HN	0.9205
399	0HO	0.9203
400	QAS	0.9200
401	GTQ	0.9198
402	UFO	0.9198
403	NPY	0.9197
404	PEY	0.9197
405	TT4	0.9197
406	GZL	0.9196
407	1F1	0.9195
408	428	0.9195
409	5M0	0.9194
410	1DW	0.9193
411	6CS	0.9193
412	SHG	0.9187
413	VOH	0.9185
414	K32	0.9185
415	5B1	0.9184
416	SKM	0.9184
417	4NC	0.9183
418	E7S	0.9183
419	JBQ	0.9179
420	DBJ	0.9179
421	4XV	0.9177
422	3BZ	0.9176
423	4FA	0.9176
424	ABI	0.9173
425	DHB	0.9173
426	5WX	0.9173
427	3Z7	0.9170
428	SKA	0.9169
429	NPO	0.9169
430	54G	0.9167
431	KOJ	0.9167
432	3U4	0.9166
433	EUG	0.9166
434	OW4	0.9166
435	069	0.9165
436	LI6	0.9164
437	KDV	0.9164
438	53C	0.9164
439	2LY	0.9163
440	BRT	0.9163
441	149	0.9163
442	1WD	0.9162
443	0JD	0.9162
444	NTZ	0.9162
445	SWD	0.9160
446	XM0	0.9160
447	IPB	0.9159
448	GCU	0.9159
449	7VJ	0.9158
450	GRE	0.9157
451	ICP	0.9156
452	GIV	0.9156
453	0F9	0.9156
454	G5V	0.9154
455	6NI	0.9152
456	BPU	0.9151
457	ASO	0.9150
458	5GU	0.9150
459	TTY	0.9150
460	K22	0.9149
461	3OC	0.9149
462	A13	0.9148
463	ES6	0.9146
464	3MA	0.9146
465	DIU	0.9144
466	JKE	0.9143
467	TH0	0.9143
468	32X	0.9138
469	LGC	0.9137
470	2ZV	0.9136
471	7WR	0.9136
472	ZZ3	0.9135
473	G2F	0.9135
474	5UC	0.9134
475	LSA	0.9134
476	TDR	0.9133
477	F12	0.9133
478	3A9	0.9133
479	6F0	0.9133
480	CFF	0.9133
481	YQA	0.9130
482	ADK	0.9129
483	37T	0.9129
484	WBU	0.9128
485	M0Q	0.9126
486	INO	0.9126
487	7WV	0.9124
488	C2Y	0.9122
489	PD2	0.9122
490	8W9	0.9120
491	GLA	0.9120
492	DFB	0.9120
493	URF	0.9119
494	NDH	0.9119
495	9TZ	0.9118
496	1PT	0.9117
497	MCT	0.9116
498	TIU	0.9115
499	JG8	0.9112
500	6M1	0.9111
501	NAG	0.9111
502	1MC	0.9110
503	4HO	0.9110
504	LT2	0.9109
505	PHB	0.9109
506	TSS	0.9109
507	XX2	0.9107
508	TOF	0.9107
509	39A	0.9107
510	173	0.9102
511	GTR	0.9102
512	PYD	0.9098
513	BMA	0.9098
514	93K	0.9097
515	0FN	0.9097
516	A29	0.9094
517	4XS	0.9094
518	HBA	0.9094
519	LDR	0.9092
520	EMZ	0.9092
521	9CA	0.9092
522	JA8	0.9091
523	XYD	0.9090
524	2KA	0.9090
525	MYJ	0.9089
526	NNO	0.9089
527	F31	0.9088
528	15N	0.9087
529	2BG	0.9086
530	4A3	0.9085
531	HNQ	0.9085
532	DEN	0.9085
533	3FH	0.9085
534	2AC	0.9084
535	329	0.9083
536	BK9	0.9083
537	IFL	0.9082
538	293	0.9082
539	HLD	0.9081
540	CH9	0.9081
541	5MK	0.9080
542	II6	0.9080
543	3HM	0.9078
544	MPI	0.9078
545	JZ2	0.9078
546	PFB	0.9078
547	1GN	0.9077
548	QOS	0.9076
549	A1U	0.9076
550	R8S	0.9076
551	BR9	0.9075
552	JAW	0.9073
553	VXX	0.9073
554	NOY	0.9073
555	34A	0.9072
556	4JJ	0.9072
557	DNF	0.9072
558	OMD	0.9072
559	XBZ	0.9071
560	4ZE	0.9071
561	4CL	0.9070
562	2MP	0.9069
563	MBG	0.9069
564	2FY	0.9068
565	6KT	0.9068
566	MZG	0.9067
567	12T	0.9066
568	MWM	0.9064
569	K17	0.9064
570	27Y	0.9063
571	FHB	0.9061
572	43M	0.9061
573	DNC	0.9060
574	LZ1	0.9059
575	DHQ	0.9059
576	NIZ	0.9059
577	2HO	0.9057
578	BZF	0.9056
579	P9P	0.9056
580	PAB	0.9056
581	25W	0.9056
582	PX7	0.9055
583	X05	0.9054
584	0R1	0.9051
585	BZI	0.9048
586	NTM	0.9047
587	HQJ	0.9047
588	GVH	0.9045
589	717	0.9045
590	2CK	0.9044
591	5MH	0.9043
592	HBD	0.9043
593	IND	0.9040
594	9AP	0.9040
595	J9Q	0.9040
596	DGJ	0.9040
597	TBS	0.9040
598	QSH	0.9038
599	PZI	0.9038
600	SX1	0.9037
601	B2J	0.9037
602	PNZ	0.9037
603	39U	0.9036
604	RIP	0.9035
605	2LP	0.9034
606	X0W	0.9033
607	MWJ	0.9033
608	3XX	0.9033
609	H5B	0.9031
610	4P5	0.9031
611	JIF	0.9030
612	Z82	0.9030
613	BHO	0.9028
614	HX3	0.9027
615	ZVO	0.9027
616	RSF	0.9027
617	FRU	0.9026
618	7B3	0.9023
619	X8D	0.9021
620	TM7	0.9020
621	1Y6	0.9020
622	XYS	0.9020
623	4BY	0.9019
624	0CT	0.9017
625	1IT	0.9017
626	PHT	0.9017
627	FBG	0.9017
628	51R	0.9016
629	8OZ	0.9015
630	15L	0.9014
631	DPZ	0.9013
632	E1T	0.9013
633	Q7A	0.9013
634	AA	0.9012
635	IUR	0.9011
636	I6G	0.9011
637	MWP	0.9011
638	JDN	0.9009
639	C9E	0.9008
640	4JO	0.9008
641	RPQ	0.9008
642	GYE	0.9008
643	FGZ	0.9007
644	0MK	0.9007
645	HKD	0.9004
646	0GZ	0.9003
647	8XQ	0.9003
648	GJP	0.9003
649	X09	0.9000
650	GCB	0.9000
651	BZ2	0.9000
652	FUL	0.9000
653	NDG	0.9000
654	F5B	0.8999
655	2YU	0.8999
656	GAF	0.8999
657	NGO	0.8998
658	JZ3	0.8997
659	MAN	0.8996
660	JU2	0.8994
661	ONR	0.8994
662	ESI	0.8994
663	15E	0.8993
664	EVA	0.8993
665	DIE	0.8992
666	0W1	0.8990
667	7MH	0.8990
668	GIF	0.8988
669	HLR	0.8987
670	8G0	0.8987
671	1WG	0.8986
672	226	0.8985
673	FLV	0.8984
674	ANN	0.8984
675	CFI	0.8984
676	CHB	0.8983
677	2K8	0.8983
678	M2H	0.8981
679	ZYR	0.8981
680	DHR	0.8979
681	EJZ	0.8979
682	HT4	0.8978
683	XXR	0.8977
684	HA7	0.8975
685	JUG	0.8974
686	9TW	0.8972
687	PBZ	0.8972
688	YRL	0.8970
689	FUC	0.8970
690	0R0	0.8969
691	ISZ	0.8968
692	QSB	0.8967
693	WOO	0.8967
694	OA3	0.8966
695	HHS	0.8966
696	5JC	0.8965
697	JFJ	0.8962
698	AEF	0.8961
699	DEE	0.8961
700	4ZC	0.8960
701	KTW	0.8960
702	K97	0.8960
703	W81	0.8959
704	SOR	0.8958
705	4VP	0.8957
706	BPN	0.8956
707	GXL	0.8953
708	YSO	0.8951
709	VNJ	0.8951
710	PA1	0.8951
711	NK	0.8949
712	TYL	0.8949
713	6BL	0.8948
714	AGK	0.8947
715	H8N	0.8947
716	4BL	0.8946
717	174	0.8946
718	826	0.8945
719	3SK	0.8945
720	X6X	0.8944
721	IF7	0.8943
722	BCU	0.8942
723	DBX	0.8942
724	IUP	0.8940
725	TLD	0.8940
726	LKA	0.8940
727	HA5	0.8940
728	ICB	0.8939
729	L5V	0.8938
730	8HC	0.8938
731	OXQ	0.8937
732	4MA	0.8937
733	MNM	0.8937
734	ANF	0.8936
735	150	0.8935
736	QWN	0.8935
737	FUD	0.8935
738	G1O	0.8934
739	IDM	0.8934
740	T6C	0.8933
741	LDP	0.8931
742	35C	0.8930
743	KLW	0.8930
744	E35	0.8929
745	7MX	0.8929
746	3QV	0.8928
747	K37	0.8927
748	OVP	0.8927
749	UNJ	0.8927
750	ISE	0.8927
751	INS	0.8926
752	PJW	0.8925
753	3AL	0.8924
754	P92	0.8923
755	NGT	0.8923
756	0FK	0.8922
757	3ZB	0.8922
758	PFL	0.8922
759	SRO	0.8921
760	ZZZ	0.8921
761	5VL	0.8921
762	ZWZ	0.8920
763	JZ9	0.8920
764	IAC	0.8920
765	AZF	0.8919
766	GCO	0.8919
767	IHB	0.8918
768	FH2	0.8918
769	4KL	0.8917
770	3RK	0.8917
771	BEZ	0.8916
772	G12	0.8915
773	JBK	0.8915
774	HDH	0.8914
775	30G	0.8914
776	Y8I	0.8913
777	9ZE	0.8911
778	ZB1	0.8911
779	O2A	0.8910
780	GBD	0.8908
781	ZZ8	0.8907
782	IFM	0.8907
783	BAM	0.8907
784	47J	0.8906
785	GLY PRO	0.8906
786	FBT	0.8906
787	5NE	0.8905
788	2CQ	0.8904
789	EKZ	0.8904
790	Q77	0.8904
791	FDK	0.8903
792	ESP	0.8903
793	GOX	0.8902
794	P72	0.8902
795	YCP	0.8902
796	DMJ	0.8901
797	BEN	0.8899
798	6FZ	0.8899
799	4VS	0.8898
800	GAG	0.8896
801	NCA	0.8896
802	27B	0.8896
803	E5X	0.8895
804	SLS	0.8894
805	BZJ	0.8893
806	BSX	0.8892
807	ADA	0.8892
808	4WL	0.8891
809	6TZ	0.8890
810	1KP	0.8888
811	DFU	0.8888
812	DRG	0.8887
813	1AL	0.8886
814	4RU	0.8886
815	ARB	0.8886
816	6PC	0.8885
817	8XL	0.8885
818	NBZ	0.8884
819	FA3	0.8883
820	3R6	0.8882
821	344	0.8879
822	1P3	0.8879
823	GTL	0.8878
824	JXN	0.8878
825	AC6	0.8878
826	FBW	0.8878
827	GVG	0.8878
828	1HN	0.8877
829	KYD	0.8877
830	IFP	0.8875
831	QXW	0.8875
832	FB1	0.8872
833	OAA	0.8871
834	OXZ	0.8870
835	CN0	0.8869
836	23J	0.8869
837	FA1	0.8867
838	G4D	0.8866
839	GV9	0.8864
840	JFD	0.8864
841	4BZ	0.8864
842	ASC	0.8860
843	H7Y	0.8860
844	3DO	0.8860
845	PHU	0.8860
846	KBG	0.8859
847	NVU	0.8858
848	EYK	0.8856
849	DX3	0.8856
850	AEZ	0.8856
851	OW7	0.8855
852	DNA	0.8855
853	PHH	0.8855
854	NIO	0.8855
855	MVL	0.8855
856	ROI	0.8854
857	286	0.8853
858	NCT	0.8852
859	6LW	0.8851
860	LYL	0.8850
861	AIN	0.8850
862	SR1	0.8849
863	SW7	0.8848
864	FBU	0.8848
865	GIM	0.8848
866	K8X	0.8848
867	39O	0.8846
868	JR2	0.8845
869	60P	0.8844
870	FBM	0.8844
871	3AY	0.8844
872	XXP	0.8844
873	JYB	0.8843
874	GHM	0.8843
875	RD4	0.8842
876	HTP	0.8842
877	EXO	0.8842
878	FPY	0.8841
879	LCN	0.8839
880	GT0	0.8839
881	RMN	0.8839
882	JKZ	0.8838
883	F1A	0.8837
884	IDH	0.8836
885	M4E	0.8836
886	SN4	0.8835
887	RIB	0.8834
888	GTZ	0.8834
889	R8A	0.8834
890	PZA	0.8833
891	AX2	0.8832
892	RHU	0.8831
893	THA	0.8831
894	TBP	0.8830
895	NSG	0.8830
896	RBL	0.8830
897	N3W	0.8829
898	CKA	0.8828
899	OTR	0.8828
900	1X7	0.8826
901	OTD	0.8826
902	X0V	0.8825
903	4ZA	0.8825
904	I1E	0.8822
905	45C	0.8822
906	PYG	0.8821
907	7D2	0.8820
908	ZXD	0.8820
909	DQN	0.8819
910	TC7	0.8818
911	PKU	0.8818
912	YIO	0.8816
913	GNM	0.8816
914	9FE	0.8815
915	J01	0.8815
916	6UA	0.8814
917	NTN	0.8814
918	F4Z	0.8813
919	AY4	0.8813
920	HY3	0.8812
921	AFR	0.8811
922	TPA	0.8811
923	H6B	0.8810
924	GNL	0.8809
925	4NM	0.8809
926	PHE	0.8807
927	APS	0.8806
928	BDF	0.8805
929	F69	0.8805
930	5ZE	0.8804
931	RAM	0.8803
932	RB5	0.8803
933	CIT	0.8803
934	1A7	0.8801
935	BR8	0.8801
936	EN1	0.8801
937	HHT	0.8801
938	EXD	0.8800
939	MFB	0.8800
940	091	0.8798
941	0XT	0.8797
942	FAN	0.8796
943	A65	0.8796
944	J9N	0.8794
945	FCR	0.8794
946	4JM	0.8793
947	VGL	0.8792
948	FBV	0.8792
949	FCB	0.8792
950	UFV	0.8791
951	49O	0.8791
952	MSR	0.8791
953	RNS	0.8789
954	LT8	0.8789
955	IPZ	0.8787
956	QX2	0.8787
957	42J	0.8786
958	RM4	0.8786
959	GF4	0.8786
960	EOL	0.8785
961	GCV	0.8785
962	RSO	0.8785
963	NGA	0.8785
964	AJY	0.8784
965	AC0	0.8784
966	13X	0.8783
967	UNU	0.8783
968	QWW	0.8781
969	AN3	0.8781
970	1WC	0.8781
971	ALL	0.8780
972	2HC	0.8780
973	JB8	0.8779
974	PIY	0.8776
975	5WU	0.8775
976	GMN	0.8775
977	HFB	0.8773
978	K6X	0.8773
979	67X	0.8772
980	XCZ	0.8771
981	60Q	0.8771
982	0LH	0.8771
983	FCA	0.8770
984	K82	0.8770
985	3MC	0.8769
986	2DR	0.8769
987	GOG	0.8768
988	ESX	0.8768
989	28N	0.8767
990	14J	0.8765
991	KTJ	0.8765
992	QIC	0.8765
993	6MH	0.8764
994	C2A	0.8764
995	F2W	0.8764
996	V6F	0.8761
997	GOO	0.8761
998	LMR	0.8760
999	SNO	0.8760
1000	MBD	0.8757
1001	3FA	0.8757
1002	N7I	0.8756
1003	HXX	0.8754
1004	4JP	0.8754
1005	5NS	0.8753
1006	7I2	0.8752
1007	DUB	0.8752
1008	XUL	0.8751
1009	ABE	0.8750
1010	2MY	0.8750
1011	12M	0.8750
1012	R20	0.8750
1013	FFP	0.8749
1014	FUF	0.8749
1015	NGW	0.8748
1016	SVD	0.8744
1017	AMG	0.8743
1018	PCA	0.8742
1019	2ZX	0.8741
1020	A7H	0.8741
1021	PIM	0.8741
1022	SF9	0.8740
1023	2MN	0.8740
1024	06B	0.8740
1025	BCF	0.8739
1026	GLF	0.8738
1027	GLT	0.8737
1028	TFU	0.8737
1029	WDL	0.8736
1030	MT5	0.8734
1031	XRG	0.8733
1032	H76	0.8732
1033	F9P	0.8732
1034	2C9	0.8731
1035	SJ5	0.8730
1036	LNR	0.8730
1037	2GS	0.8729
1038	259	0.8728
1039	L99	0.8728
1040	3CE	0.8727
1041	IP0	0.8727
1042	SRT	0.8727
1043	TSU	0.8727
1044	4I8	0.8725
1045	JP2	0.8724
1046	F4E	0.8724
1047	BBF	0.8723
1048	FBA	0.8723
1049	7CZ	0.8721
1050	2CM	0.8721
1051	JLZ	0.8721
1052	P84	0.8720
1053	4SX	0.8720
1054	FLC	0.8720
1055	ERH	0.8717
1056	MHK	0.8716
1057	1XA	0.8715
1058	P9E	0.8715
1059	8GK	0.8715
1060	BPY	0.8714
1061	PZM	0.8713
1062	PBA	0.8711
1063	FLM	0.8709
1064	PBC	0.8708
1065	IBF	0.8706
1066	1U6	0.8705
1067	RNO	0.8703
1068	SNU	0.8702
1069	0TR	0.8701
1070	GSY	0.8699
1071	TXW	0.8699
1072	4FH	0.8698
1073	4VY	0.8697
1074	URQ	0.8696
1075	23W	0.8696
1076	CFA	0.8695
1077	NLA	0.8692
1078	5AN	0.8689
1079	95Z	0.8688
1080	FPK	0.8687
1081	1U1	0.8683
1082	FQI	0.8683
1083	68A	0.8682
1084	MMA	0.8682
1085	4NB	0.8679
1086	DYA	0.8676
1087	AEH	0.8675
1088	DA4	0.8675
1089	1DV	0.8675
1090	5FN	0.8673
1091	275	0.8673
1092	P3K	0.8673
1093	EGR	0.8673
1094	V1T	0.8671
1095	7FF	0.8668
1096	5LA	0.8668
1097	K25	0.8665
1098	DQA	0.8665
1099	AAS	0.8664
1100	6XI	0.8663
1101	KP6	0.8662
1102	18N	0.8662
1103	SLC	0.8660
1104	CRS	0.8660
1105	BNT	0.8659
1106	AH8	0.8657
1107	K34	0.8656
1108	TAR	0.8653
1109	DE5	0.8651
1110	M5N	0.8650
1111	WOT	0.8650
1112	HBO	0.8650
1113	X0U	0.8650
1114	549	0.8649
1115	61M	0.8649
1116	GCW	0.8641
1117	N2Z	0.8641
1118	ENL	0.8641
1119	Q02	0.8641
1120	B56	0.8639
1121	7WG	0.8637
1122	94N	0.8636
1123	F3B	0.8634
1124	9PY	0.8634
1125	282	0.8631
1126	LRH	0.8630
1127	DHS	0.8628
1128	JZ4	0.8628
1129	4V2	0.8627
1130	46P	0.8627
1131	FHN	0.8627
1132	HBX	0.8627
1133	TLA	0.8625
1134	QSC	0.8624
1135	6OT	0.8623
1136	RCO	0.8623
1137	SYN	0.8622
1138	IWT	0.8621
1139	5TY	0.8620
1140	SG2	0.8616
1141	URA	0.8615
1142	CGB	0.8609
1143	PRY	0.8607
1144	QQQ	0.8606
1145	MAJ	0.8606
1146	4P0	0.8601
1147	PCI	0.8600
1148	N8P	0.8600
1149	3MH	0.8598
1150	N7P	0.8598
1151	PYF	0.8596
1152	6Q3	0.8593
1153	3R4	0.8593
1154	5CL	0.8591
1155	3V4	0.8590
1156	HQE	0.8589
1157	LQ2	0.8588
1158	CYT	0.8584
1159	FA6	0.8580
1160	TCZ	0.8578
1161	RAT	0.8578
1162	TZF	0.8575
1163	OK7	0.8574
1164	3GQ	0.8574
1165	TVP	0.8573
1166	2O6	0.8571
1167	LG3	0.8569
1168	PCR	0.8558
1169	PXY	0.8558
1170	4TE	0.8555
1171	5OF	0.8554
1172	PLQ	0.8551
1173	4A5	0.8550
1174	25R	0.8547
1175	HPT	0.8543
1176	R2B	0.8542
1177	3J8	0.8539
1178	LG5	0.8539
1179	J1Z	0.8536
1180	BVF	0.8529
1181	DA1	0.8525
1182	XQK	0.8520
1183	L3Q	0.8520
1184	26D	0.8520
1185	FPN	0.8516

Similar Binding Sites (Proteins are less than 50% similar to leader)

Pocket No.: 1; Query (leader) PDB : 1B8O; Ligand: IMH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.

This union binding pocket(no: 1) in the query (biounit: 1b8o.bio1) has 48 residues
No:	Leader PDB	Ligand	Sequence Similarity

Pocket No.: 2; Query (leader) PDB : 1B8O; Ligand: IMH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.

This union binding pocket(no: 2) in the query (biounit: 1b8o.bio2) has 48 residues
No:	Leader PDB	Ligand	Sequence Similarity

Pocket No.: 3; Query (leader) PDB : 1B8O; Ligand: IMH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.

This union binding pocket(no: 3) in the query (biounit: 1b8o.bio2) has 48 residues
No:	Leader PDB	Ligand	Sequence Similarity

Pocket No.: 4; Query (leader) PDB : 1B8O; Ligand: IMH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.

This union binding pocket(no: 4) in the query (biounit: 1b8o.bio2) has 48 residues
No:	Leader PDB	Ligand	Sequence Similarity

APoc FAQ