Receptor
PDB id Resolution Class Description Source Keywords
2Q1H 1.9 Å NON-ENZYME: SIGNAL_HORMONE ANCESTRAL CORTICOID RECEPTOR IN COMPLEX WITH ALDOSTERONE UNIDENTIFIED NUCLEAR RECEPTOR LIGAND BINDING DOMAIN ALDOSTERONE EVOLUTANCIENT PROTEIN EPISTASIS UNKNOWN FUNCTION TRANSCRIPTION
Ref.: CRYSTAL STRUCTURE OF AN ANCIENT PROTEIN: EVOLUTION CONFORMATIONAL EPISTASIS. SCIENCE V. 317 1544 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
AS4 A:301;
Valid;
none;
submit data
360.444 C21 H28 O5 C[C@]...
GOL A:403;
A:404;
Invalid;
Invalid;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
NA A:248;
A:249;
Part of Protein;
Part of Protein;
none;
none;
submit data
22.99 Na [Na+]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2Q1H 1.9 Å NON-ENZYME: SIGNAL_HORMONE ANCESTRAL CORTICOID RECEPTOR IN COMPLEX WITH ALDOSTERONE UNIDENTIFIED NUCLEAR RECEPTOR LIGAND BINDING DOMAIN ALDOSTERONE EVOLUTANCIENT PROTEIN EPISTASIS UNKNOWN FUNCTION TRANSCRIPTION
Ref.: CRYSTAL STRUCTURE OF AN ANCIENT PROTEIN: EVOLUTION CONFORMATIONAL EPISTASIS. SCIENCE V. 317 1544 2007
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 263 families.
1 4LTW - STR C21 H30 O2 CC(=O)[C@H....
2 2Q1H - AS4 C21 H28 O5 C[C@]12CCC....
3 2Q3Y - PRO ALA ILE LEU TYR ALA LEU LEU SER SER n/a n/a
4 2Q1V - PDN C21 H26 O5 C[C@]12CC(....
70% Homology Family (83)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 196 families.
1 3RY9 - 1CA C21 H30 O3 C[C@]12CC[....
2 1XNN Ki = 0.5 nM HYQ C20 H18 N2 O4 c1ccc2c(c1....
3 2AMA - DHT C19 H30 O2 C[C@]12CCC....
4 2AX9 Ki = 0.3 nM BHM C11 H10 Br F3 N2 O4 C[C@](CBr)....
5 2AMB - 17H C21 H28 O2 CC[C@@]1(C....
6 4OEA - DHT C19 H30 O2 C[C@]12CCC....
7 3B67 - B67 C17 H10 F8 N2 O5 C[C@](COc1....
8 2PIU - DHT C19 H30 O2 C[C@]12CCC....
9 2YLO - TES C19 H28 O2 C[C@]12CC[....
10 2PNU - ENM C27 H36 F2 O3 C[C@]12CCC....
11 4HLW - 17W C15 H14 N2 O S c1ccc(cc1)....
12 2PIQ - RB1 C16 H19 N5 O CC(C)(C)n1....
13 2HVC - LGD C14 H9 F9 N2 O c1cc2c(cc1....
14 2OZ7 - CA4 C24 H29 Cl O4 CC(=O)[C@]....
15 3B65 - 3B6 C18 H14 I N3 O3 C[C@](COc1....
16 5CJ6 Ki = 2.03 nM 51Y C14 H17 Cl N2 O Cc1c(ccc(c....
17 4QL8 ic50 = 0.7 nM JAD C15 H16 Cl N3 O2 Cc1c(ccc(c....
18 3B5R - B5R C18 H13 Cl F4 N2 O3 C[C@](COc1....
19 2AX8 - FHM C17 H14 F4 N2 O5 C[C@](COc1....
20 2QPY - DHT C19 H30 O2 C[C@]12CCC....
21 1T7T - DHT C19 H30 O2 C[C@]12CCC....
22 1Z95 Kd = 0.76 nM 198 C18 H14 F4 N2 O4 S C[C@](CS(=....
23 3RLJ - RLJ C19 H14 F3 N3 O3 C[C@](COc1....
24 2AX7 - FHM C17 H14 F4 N2 O5 C[C@](COc1....
25 3ZQT - TES C19 H28 O2 C[C@]12CC[....
26 1GS4 - ZK5 C21 H29 F O5 C[C@]12CCC....
27 2AM9 - TES C19 H28 O2 C[C@]12CC[....
28 3B66 - B66 C18 H16 F3 N3 O5 C[C@](COc1....
29 2PIT - DHT C19 H30 O2 C[C@]12CCC....
30 3G0W Ki = 0.3 nM LGB C15 H13 Cl F3 N3 O2 Cc1c(ccc(c....
31 1I38 - DHT C19 H30 O2 C[C@]12CCC....
32 2PIP - ICO C9 H7 N O2 c1ccc2c(c1....
33 1E3G - R18 C19 H24 O2 C[C@@]1(CC....
34 3RLL - RLL C23 H16 F3 N3 O3 C[C@](COc1....
35 2AXA Ki = 6.1 nM FHM C17 H14 F4 N2 O5 C[C@](COc1....
36 2IHQ Ki = 3.2 nM LG7 C17 H13 N3 O3 c1ccc2c(c1....
37 3B68 - B68 C19 H18 F3 N3 O6 CC(=O)Nc1c....
38 2PIV - T3 C15 H12 I3 N O4 c1cc(c(cc1....
39 2PIX - FLF C14 H10 F3 N O2 c1ccc(c(c1....
40 2PIR - NK C7 H6 O2 c1ccc(c(c1....
41 2YHD Ki = 23 uM AV6 C17 H14 N2 O2 c1cc2cccc3....
42 2AX6 - HFT C11 H11 F3 N2 O4 CC(C)(C(=O....
43 2PKL - DHT C19 H30 O2 C[C@]12CCC....
44 2PIO - DHT C19 H30 O2 C[C@]12CCC....
45 1XQ3 - R18 C19 H24 O2 C[C@@]1(CC....
46 5V8Q ic50 = 3.6 nM 97A C14 H13 F3 N2 O2 CC[C@H]1[C....
47 4OJB - 198 C18 H14 F4 N2 O4 S C[C@](CS(=....
48 2YLQ - TES C19 H28 O2 C[C@]12CC[....
49 1I37 - DHT C19 H30 O2 C[C@]12CCC....
50 2YLP - TES C19 H28 O2 C[C@]12CC[....
51 3VHV ic50 = 510 nM LD1 C18 H13 N5 O2 S c1ccc(cc1)....
52 1YA3 - STR C21 H30 O2 CC(=O)[C@H....
53 2AAX - PDN C21 H26 O5 C[C@]12CC(....
54 2AA7 - 1CA C21 H30 O3 C[C@]12CC[....
55 4PF3 ic50 = 71 nM HFN C21 H18 F3 N3 O3 Cc1c(c(n(n....
56 2AB2 - SNL C24 H32 O4 S CC(=O)S[C@....
57 2AA2 - AS4 C21 H28 O5 C[C@]12CCC....
58 5HCV Ki = 2 nM 60R C23 H16 F N O3 c1ccc2c(c1....
59 2OAX - SNL C24 H32 O4 S CC(=O)S[C@....
60 1Y9R - 1CA C21 H30 O3 C[C@]12CC[....
61 2AA6 - STR C21 H30 O2 CC(=O)[C@H....
62 1SQN Kd = 0.4 nM NDR C20 H26 O2 C[C@]12CC[....
63 3ZRB - OR8 C17 H19 Cl N4 O3 S Cc1c(c(on1....
64 4APU - OR8 C17 H19 Cl N4 O3 S Cc1c(c(on1....
65 3HQ5 ic50 = 16 nM GKK C20 H19 Cl F3 N3 C[N@]1CC[C....
66 1ZUC ic50 = 1.7 nM T98 C16 H15 N3 O S CC1(c2cc(c....
67 3ZR7 - OR8 C17 H19 Cl N4 O3 S Cc1c(c(on1....
68 1SR7 Kd = 0.08 nM MOF C27 H30 Cl2 O6 C[C@@H]1C[....
69 3D90 - NOG C21 H28 O2 CC[C@]12CC....
70 3ZRA - ORB C18 H17 Cl F N3 O3 S Cc1c(c(on1....
71 3G8O ic50 = 125 nM 30X C15 H15 F6 N3 O C[C@@H](C(....
72 3KBA ic50 = 16 nM WOW C20 H22 Cl N3 O2 S Cc1ccccc1C....
73 4A2J - AS0 C28 H35 N O4 C[C@]12C[C....
74 2W8Y - NDR C20 H26 O2 C[C@]12CC[....
75 1A28 Ki = 5.1 nM STR C21 H30 O2 CC(=O)[C@H....
76 1NHZ - 486 C29 H35 N O2 CC#C[C@@]1....
77 4LTW - STR C21 H30 O2 CC(=O)[C@H....
78 2Q1H - AS4 C21 H28 O5 C[C@]12CCC....
79 2Q3Y - PRO ALA ILE LEU TYR ALA LEU LEU SER SER n/a n/a
80 2Q1V - PDN C21 H26 O5 C[C@]12CC(....
81 5L7H Ki = 50 nM 6QG C21 H22 N2 O4 S Cc1c-2c(on....
82 5L7E Ki = 0.25 uM 6Q0 C18 H18 N2 O3 S Cc1c(c(on1....
83 5L7G Ki = 16 nM 6QE C22 H22 F2 N2 O4 S Cc1c(c(on1....
50% Homology Family (85)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 171 families.
1 3RY9 - 1CA C21 H30 O3 C[C@]12CC[....
2 1XNN Ki = 0.5 nM HYQ C20 H18 N2 O4 c1ccc2c(c1....
3 2AMA - DHT C19 H30 O2 C[C@]12CCC....
4 2AX9 Ki = 0.3 nM BHM C11 H10 Br F3 N2 O4 C[C@](CBr)....
5 2AMB - 17H C21 H28 O2 CC[C@@]1(C....
6 4OEA - DHT C19 H30 O2 C[C@]12CCC....
7 3B67 - B67 C17 H10 F8 N2 O5 C[C@](COc1....
8 2PIU - DHT C19 H30 O2 C[C@]12CCC....
9 2YLO - TES C19 H28 O2 C[C@]12CC[....
10 2PNU - ENM C27 H36 F2 O3 C[C@]12CCC....
11 4HLW - 17W C15 H14 N2 O S c1ccc(cc1)....
12 2PIQ - RB1 C16 H19 N5 O CC(C)(C)n1....
13 2HVC - LGD C14 H9 F9 N2 O c1cc2c(cc1....
14 2OZ7 - CA4 C24 H29 Cl O4 CC(=O)[C@]....
15 3B65 - 3B6 C18 H14 I N3 O3 C[C@](COc1....
16 5CJ6 Ki = 2.03 nM 51Y C14 H17 Cl N2 O Cc1c(ccc(c....
17 4QL8 ic50 = 0.7 nM JAD C15 H16 Cl N3 O2 Cc1c(ccc(c....
18 3B5R - B5R C18 H13 Cl F4 N2 O3 C[C@](COc1....
19 2AX8 - FHM C17 H14 F4 N2 O5 C[C@](COc1....
20 2QPY - DHT C19 H30 O2 C[C@]12CCC....
21 1T7T - DHT C19 H30 O2 C[C@]12CCC....
22 1Z95 Kd = 0.76 nM 198 C18 H14 F4 N2 O4 S C[C@](CS(=....
23 3RLJ - RLJ C19 H14 F3 N3 O3 C[C@](COc1....
24 2AX7 - FHM C17 H14 F4 N2 O5 C[C@](COc1....
25 3ZQT - TES C19 H28 O2 C[C@]12CC[....
26 1GS4 - ZK5 C21 H29 F O5 C[C@]12CCC....
27 2AM9 - TES C19 H28 O2 C[C@]12CC[....
28 3B66 - B66 C18 H16 F3 N3 O5 C[C@](COc1....
29 2PIT - DHT C19 H30 O2 C[C@]12CCC....
30 3G0W Ki = 0.3 nM LGB C15 H13 Cl F3 N3 O2 Cc1c(ccc(c....
31 1I38 - DHT C19 H30 O2 C[C@]12CCC....
32 2PIP - ICO C9 H7 N O2 c1ccc2c(c1....
33 1E3G - R18 C19 H24 O2 C[C@@]1(CC....
34 3RLL - RLL C23 H16 F3 N3 O3 C[C@](COc1....
35 2AXA Ki = 6.1 nM FHM C17 H14 F4 N2 O5 C[C@](COc1....
36 2IHQ Ki = 3.2 nM LG7 C17 H13 N3 O3 c1ccc2c(c1....
37 3B68 - B68 C19 H18 F3 N3 O6 CC(=O)Nc1c....
38 2PIV - T3 C15 H12 I3 N O4 c1cc(c(cc1....
39 2PIX - FLF C14 H10 F3 N O2 c1ccc(c(c1....
40 2PIR - NK C7 H6 O2 c1ccc(c(c1....
41 2YHD Ki = 23 uM AV6 C17 H14 N2 O2 c1cc2cccc3....
42 2AX6 - HFT C11 H11 F3 N2 O4 CC(C)(C(=O....
43 2PKL - DHT C19 H30 O2 C[C@]12CCC....
44 2PIO - DHT C19 H30 O2 C[C@]12CCC....
45 1XQ3 - R18 C19 H24 O2 C[C@@]1(CC....
46 5V8Q ic50 = 3.6 nM 97A C14 H13 F3 N2 O2 CC[C@H]1[C....
47 4OJB - 198 C18 H14 F4 N2 O4 S C[C@](CS(=....
48 2YLQ - TES C19 H28 O2 C[C@]12CC[....
49 1I37 - DHT C19 H30 O2 C[C@]12CCC....
50 2YLP - TES C19 H28 O2 C[C@]12CC[....
51 3VHU ic50 = 49 nM SNL C24 H32 O4 S CC(=O)S[C@....
52 2AA5 - STR C21 H30 O2 CC(=O)[C@H....
53 3VHV ic50 = 510 nM LD1 C18 H13 N5 O2 S c1ccc(cc1)....
54 1YA3 - STR C21 H30 O2 CC(=O)[C@H....
55 2AAX - PDN C21 H26 O5 C[C@]12CC(....
56 2AA7 - 1CA C21 H30 O3 C[C@]12CC[....
57 4PF3 ic50 = 71 nM HFN C21 H18 F3 N3 O3 Cc1c(c(n(n....
58 2AB2 - SNL C24 H32 O4 S CC(=O)S[C@....
59 2AA2 - AS4 C21 H28 O5 C[C@]12CCC....
60 5HCV Ki = 2 nM 60R C23 H16 F N O3 c1ccc2c(c1....
61 2OAX - SNL C24 H32 O4 S CC(=O)S[C@....
62 1Y9R - 1CA C21 H30 O3 C[C@]12CC[....
63 2AA6 - STR C21 H30 O2 CC(=O)[C@H....
64 1SQN Kd = 0.4 nM NDR C20 H26 O2 C[C@]12CC[....
65 3ZRB - OR8 C17 H19 Cl N4 O3 S Cc1c(c(on1....
66 4APU - OR8 C17 H19 Cl N4 O3 S Cc1c(c(on1....
67 3HQ5 ic50 = 16 nM GKK C20 H19 Cl F3 N3 C[N@]1CC[C....
68 1ZUC ic50 = 1.7 nM T98 C16 H15 N3 O S CC1(c2cc(c....
69 3ZR7 - OR8 C17 H19 Cl N4 O3 S Cc1c(c(on1....
70 1SR7 Kd = 0.08 nM MOF C27 H30 Cl2 O6 C[C@@H]1C[....
71 3D90 - NOG C21 H28 O2 CC[C@]12CC....
72 3ZRA - ORB C18 H17 Cl F N3 O3 S Cc1c(c(on1....
73 3G8O ic50 = 125 nM 30X C15 H15 F6 N3 O C[C@@H](C(....
74 3KBA ic50 = 16 nM WOW C20 H22 Cl N3 O2 S Cc1ccccc1C....
75 4A2J - AS0 C28 H35 N O4 C[C@]12C[C....
76 2W8Y - NDR C20 H26 O2 C[C@]12CC[....
77 1A28 Ki = 5.1 nM STR C21 H30 O2 CC(=O)[C@H....
78 1NHZ - 486 C29 H35 N O2 CC#C[C@@]1....
79 4LTW - STR C21 H30 O2 CC(=O)[C@H....
80 2Q1H - AS4 C21 H28 O5 C[C@]12CCC....
81 2Q3Y - PRO ALA ILE LEU TYR ALA LEU LEU SER SER n/a n/a
82 2Q1V - PDN C21 H26 O5 C[C@]12CC(....
83 5L7H Ki = 50 nM 6QG C21 H22 N2 O4 S Cc1c-2c(on....
84 5L7E Ki = 0.25 uM 6Q0 C18 H18 N2 O3 S Cc1c(c(on1....
85 5L7G Ki = 16 nM 6QE C22 H22 F2 N2 O4 S Cc1c(c(on1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: AS4; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 AS4 1 1
2 C0R 0.647059 0.97619
3 HCY 0.544444 0.911111
4 1CA 0.431579 0.928571
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2Q1H; Ligand: AS4; Similar sites found: 169
This union binding pocket(no: 1) in the query (biounit: 2q1h.bio1) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1UO5 PIH 0.008222 0.4389 None
2 3BPX SAL 0.01234 0.42069 None
3 1UO4 PIH 0.009473 0.41513 None
4 5CSD ACD 0.01408 0.41079 None
5 3L1N PLM 0.01753 0.40845 None
6 1QY8 RDI 0.002994 0.40519 None
7 4BVM VCA 0.008322 0.40221 None
8 4BVM PLM 0.008277 0.40063 None
9 1NF8 BOG 0.001516 0.47173 0.966184
10 4MRP GSH 0.01452 0.4311 1.6
11 2YIV YIV 0.03359 0.40478 1.6
12 3P9T TCL 0.007053 0.41921 1.82648
13 2Q2Y ADP 0.00675 0.42571 2
14 2Q2Y MKR 0.00641 0.42571 2
15 3OID TCL 0.00945 0.42216 2
16 2BP1 FLC 0.009121 0.41966 2
17 1YKD CMP 0.006295 0.40563 2
18 1J78 OLA 0.009855 0.40397 2
19 3KC1 2T6 0.005801 0.40367 2
20 4W9N TCL 0.02565 0.40133 2
21 5BVT PAM 0.003093 0.40998 2.23881
22 3B99 U51 0.002114 0.43957 2.4
23 3CHT 4NB 0.005196 0.4376 2.4
24 2PX6 DH9 0.005602 0.41158 2.4
25 3IX1 NFM 0.01951 0.40607 2.4
26 4L77 CNL 0.02192 0.40347 2.4
27 3G6N MET ALA SER 0.0139 0.4136 2.6178
28 2Q4X HMH 0.01002 0.42352 2.71493
29 4F4P 0SB 0.0237 0.41291 2.8
30 1ZPD CIT 0.02434 0.41036 2.8
31 3G5D 1N1 0.03468 0.40276 2.8
32 4M0R 644 0.02662 0.40139 2.8
33 2PEH LYS ARG LYS SER ARG TRP ASP GLU THR PRO 0.008954 0.41419 2.85714
34 1GEG GLC 0.01384 0.43523 3.2
35 4QEK GLC 0.00921 0.41544 3.2
36 3EE4 MYR 0.001604 0.41404 3.2
37 2OHV NHL 0.01253 0.41136 3.2
38 4RKK GLC GLC GLC GLC GLC GLC 0.008253 0.40775 3.2
39 5B0W 22B 0.01584 0.40087 3.2
40 3GYT DL4 0.0007592 0.41642 3.27869
41 1YRX FMN 0.009197 0.40188 3.30579
42 3KP6 SAL 0.002708 0.44075 3.31126
43 2HHP FLC 0.00006947 0.57904 3.6
44 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 0.008752 0.43631 3.6
45 3B9Z CO2 0.01283 0.43372 3.6
46 4B1V LAB 0.006053 0.42241 3.6
47 3ZQE DXC 0.02484 0.40017 3.6
48 4P3H 25G 0.004558 0.40817 3.62694
49 3VM7 GLC 0.02615 0.4025 3.86179
50 2VWA PTY 0.0268 0.40625 3.9604
51 3Q8G PEE 0.005594 0.44121 4
52 2WOR 2AN 0.00808 0.43448 4
53 1TV5 N8E 0.01744 0.40855 4
54 5V4R MGT 0.01955 0.40641 4.32099
55 3WCA FPS 0.007978 0.41189 4.4
56 2CB8 MYA 0.01433 0.41752 4.5977
57 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 0.007187 0.43404 4.60251
58 1YC4 43P 0.000627 0.46439 4.8
59 5J32 IPM 0.01571 0.41318 4.8
60 3DTU DXC 0.03241 0.40026 4.8
61 4WGF HX2 0.00413 0.43874 4.87805
62 2GBB CIT 0.02064 0.40056 5.12821
63 3O01 DXC 0.0004863 0.4923 5.2
64 4B7P 9UN 0.01315 0.41769 5.21739
65 4DS8 A8S 0.003804 0.42323 5.26316
66 2QZT PLM 0.009148 0.40787 5.40541
67 5DEY 59T 0.008809 0.43013 5.6
68 5D59 78M 0.02243 0.40494 5.6
69 5MOB A8S 0.01466 0.40382 5.60345
70 5B4B LP5 0.006773 0.41642 5.64516
71 5JO1 6LM 0.007073 0.40182 5.94595
72 1A05 IPM 0.009664 0.42411 6
73 1LEK GLU GLN TYR LYS PHE TYR SER VAL 0.029 0.41299 6.06061
74 1MHC FME TYR PHE ILE ASN ILE LEU THR LEU 0.01641 0.40017 6.06061
75 3AQT RCO 0.005128 0.44114 6.12245
76 4URN NOV 0.02028 0.4052 6.22222
77 3TL1 JRO 0.0124 0.41614 6.28931
78 2YLD CMO 0.02368 0.40597 6.29921
79 5N18 8HZ 0.02167 0.40296 6.42202
80 5BV6 35G 0.006129 0.40264 6.57895
81 3HP9 CF1 0.009207 0.434 6.8
82 3RET PYR 0.004356 0.42052 6.93069
83 3RET SAL 0.004356 0.42052 6.93069
84 1SBR VIB 0.00193 0.45725 7
85 4FHT DHB 0.0108 0.42325 7.00637
86 3KYQ DPV 0.007169 0.42827 7.03518
87 5UC9 MYR 0.01327 0.41012 7.07965
88 4IGH 1EA 0.02757 0.41408 7.2
89 4IGH FMN 0.02757 0.41408 7.2
90 4IGH ORO 0.02757 0.41408 7.2
91 4OB1 BUB 0.005184 0.43698 7.29614
92 4OB0 PBC 0.006182 0.43239 7.61905
93 1XVB 3BR 0.01033 0.41118 8
94 4BIX ADP 0.02522 0.40034 8
95 2D5Z L35 0.03887 0.41197 8.21918
96 2RKN LP3 0.009577 0.40477 9.09091
97 3KDU NKS 0.0001143 0.51749 9.2
98 3FEI CTM 0.001504 0.43653 9.2
99 4V3I ASP LEU THR ARG PRO 0.01464 0.41703 9.33852
100 1RL4 BL5 0.01028 0.41303 9.57447
101 3G9E RO7 0.000149 0.49592 9.6
102 3ET3 ET1 0.00008746 0.48427 9.6
103 2PRG BRL 0.0001135 0.48218 9.6
104 3ET1 ET1 0.0004342 0.45661 9.6
105 3B1M KRC 0.003549 0.41665 9.6
106 3T03 3T0 0.001903 0.41333 9.6
107 4HEE 14R 0.003268 0.40823 9.6
108 3DLG GWE 0.02822 0.41176 10
109 4O4Z N2O 0.01539 0.4286 10.3896
110 3E3U NVC 0.007852 0.40875 10.6599
111 2ALG DAO 0.008491 0.42477 10.8696
112 1MID LAP 0.01415 0.40457 10.989
113 4R29 SAM 0.01757 0.4 11.1607
114 1DB1 VDX 0.0001666 0.49223 11.2
115 1DTL BEP 0.01193 0.40415 11.8012
116 5OCA 9QZ 0.002547 0.47109 11.9048
117 1XX4 BAM 0.01835 0.41848 12
118 4RW3 TDA 0.004408 0.40101 12
119 4RJD TFP 0.01314 0.41318 12.1212
120 3JRS A8S 0.007457 0.40599 12.5
121 3MN5 LAB 0.02334 0.40207 13.1579
122 3WBG 2AN 0.001946 0.43221 13.7255
123 3KMR EQN 0.000237 0.46332 15.6
124 4EKQ NPO 0.01045 0.41094 16.5775
125 4DK7 0KS 0.00009831 0.47971 16.5992
126 1FCZ 156 0.0003114 0.43272 17.0213
127 4URG C2E 0.01132 0.42258 19.7605
128 1YOK P6L 0.000006616 0.56101 21.4844
129 1ZDU P3A 0.0002741 0.42079 21.6327
130 5UNJ RJW 0.00004593 0.47978 22.449
131 3IPQ 965 0.00006605 0.42779 23.2
132 1YMT DR9 0.00006436 0.50434 24.7967
133 1YP0 PEF 0.0001163 0.45495 25.1046
134 3BEJ MUF 0.00001698 0.51981 25.6303
135 4QJR PIZ 0.00003443 0.45582 25.7143
136 3DCT 064 0.00002442 0.46463 25.9574
137 1ZDT PEF 0.0001387 0.48765 26.1411
138 3RUU 37G 0.00001376 0.45454 26.6376
139 5ICK FEZ 0.0006152 0.44553 26.6376
140 1M13 HYF 0.001681 0.44519 27.2
141 1NRL SRL 0.004001 0.40567 27.2
142 2LBD REA 0.0004381 0.46191 27.3408
143 1PZL MYR 0.000007393 0.5342 28.692
144 3KO0 TFP 0.0107 0.41769 28.7129
145 3FS1 MYR 0.00001105 0.53295 29.5652
146 1XAP TTB 0.0003165 0.45128 30
147 4DM8 REA 0.0004026 0.43506 30
148 1FBY REA 0.0000006346 0.53462 31.7992
149 1FM9 9CR 0.00000002955 0.6173 31.9328
150 1HG4 LPP 0.00004409 0.44312 32
151 1DKF OLA 0.0000007097 0.59442 32.618
152 1DKF BMS 0.00001826 0.486 32.618
153 1G2N EPH 0.0004069 0.42434 32.8
154 4M8E 29V 0.00000002893 0.64075 32.9004
155 4POJ 2VP 0.00000004262 0.57693 32.9004
156 3H0A 9RA 0.0000003206 0.58643 33.3333
157 1XIU REA 0.000000249 0.59879 34.3478
158 2E2R 2OH 0.00000000003299 0.56959 35.2459
159 2I0G I0G 0.0000000003895 0.7809 41.6
160 1YYE 196 0.00000000008101 0.77536 41.6
161 1U3R 338 0.00000000007593 0.75298 43.1535
162 3UUD EST 0.00000000002501 0.7988 43.2
163 2QA8 GEN 0.00000000007731 0.7763 43.2
164 3UU7 2OH 0.000000003265 0.75023 43.2
165 2QZO KN1 0.0000000001201 0.73347 43.2
166 5AAV GW5 0.000000005097 0.73345 43.2
167 3UUA 0CZ 0.000000008168 0.70525 43.2
168 2BJ4 OHT 0.0000000001642 0.70859 43.254
169 2QE4 JJ3 0.000000001933 0.74923 43.5484
170 1YUC EPH 0.00004448 0.45705 50
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