Receptor
PDB id Resolution Class Description Source Keywords
2PVF 1.8 Å EC: 2.7.10.1 CRYSTAL STRUCTURE OF TYROSINE PHOSPHORYLATED ACTIVATED FGF R (FGFR2) KINASE DOMAIN IN COMPLEX WITH ATP ANALOG AND SUBSTRP EPTIDE HOMO SAPIENS KINASE DOMAIN FOLD CONSISTING OF N- AND C-LOBES TRANSFERASE
Ref.: A MOLECULAR BRAKE IN THE KINASE HINGE REGION REGULA ACTIVITY OF RECEPTOR TYROSINE KINASES. MOL.CELL V. 27 717 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACP A:300;
Valid;
none;
submit data
505.208 C11 H18 N5 O12 P3 c1nc(...
MG A:301;
A:302;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2PVF 1.8 Å EC: 2.7.10.1 CRYSTAL STRUCTURE OF TYROSINE PHOSPHORYLATED ACTIVATED FGF R (FGFR2) KINASE DOMAIN IN COMPLEX WITH ATP ANALOG AND SUBSTRP EPTIDE HOMO SAPIENS KINASE DOMAIN FOLD CONSISTING OF N- AND C-LOBES TRANSFERASE
Ref.: A MOLECULAR BRAKE IN THE KINASE HINGE REGION REGULA ACTIVITY OF RECEPTOR TYROSINE KINASES. MOL.CELL V. 27 717 2007
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 31 families.
1 2PVF - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 16 families.
1 2PVF - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 2PVF - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ACP; Similar ligands found: 351
No: Ligand ECFP6 Tc MDL keys Tc
1 ACP 1 1
2 ACQ 0.866667 1
3 A2D 0.857143 0.945205
4 BA3 0.833333 0.945205
5 AP5 0.821918 0.945205
6 ADP 0.821918 0.972222
7 B4P 0.821918 0.945205
8 AN2 0.810811 0.958904
9 AP2 0.808219 0.986301
10 A12 0.808219 0.986301
11 M33 0.8 0.932432
12 ATP 0.789474 0.972222
13 5FA 0.779221 0.972222
14 AQP 0.779221 0.972222
15 AR6 0.779221 0.945205
16 APR 0.779221 0.945205
17 AGS 0.769231 0.921053
18 SAP 0.769231 0.921053
19 AD9 0.769231 0.945946
20 A 0.763889 0.944444
21 AMP 0.763889 0.944444
22 APC 0.75641 0.986301
23 CA0 0.753247 0.92
24 ADX 0.753247 0.851852
25 ANP 0.75 0.945946
26 50T 0.74359 0.932432
27 PRX 0.734177 0.87013
28 ABM 0.733333 0.893333
29 ATF 0.731707 0.933333
30 AMP MG 0.72 0.868421
31 SRA 0.706667 0.894737
32 A22 0.705882 0.958904
33 RBY 0.703704 0.959459
34 ADV 0.703704 0.959459
35 5AL 0.698795 0.906667
36 ADQ 0.689655 0.92
37 A1R 0.689655 0.909091
38 AU1 0.6875 0.945946
39 ADP MG 0.6875 0.881579
40 TAT 0.686747 0.933333
41 SRP 0.682353 0.907895
42 BEF ADP 0.679012 0.858974
43 ADP BEF 0.679012 0.858974
44 OAD 0.674157 0.92
45 4TC 0.673469 0.922078
46 4AD 0.670455 0.921053
47 AMO 0.670455 0.933333
48 00A 0.662921 0.860759
49 ADP PO3 0.662651 0.917808
50 3OD 0.659341 0.92
51 BIS 0.659341 0.909091
52 25A 0.659091 0.945205
53 8QN 0.659091 0.906667
54 5SV 0.659091 0.82716
55 OOB 0.659091 0.906667
56 ATP MG 0.654762 0.881579
57 SON 0.654321 0.933333
58 25L 0.652174 0.958904
59 PAJ 0.651685 0.8625
60 DLL 0.644444 0.906667
61 AHX 0.644444 0.897436
62 TXA 0.641304 0.907895
63 3UK 0.637363 0.894737
64 ADP ALF 0.632184 0.848101
65 ALF ADP 0.632184 0.848101
66 WAQ 0.630435 0.884615
67 LAD 0.630435 0.8625
68 PR8 0.630435 0.851852
69 MAP 0.629214 0.921053
70 GAP 0.627907 0.87013
71 ANP MG 0.625 0.871795
72 ADP VO4 0.625 0.906667
73 VO4 ADP 0.625 0.906667
74 ME8 0.623656 0.841463
75 PTJ 0.623656 0.873418
76 NB8 0.623656 0.897436
77 1ZZ 0.623656 0.819277
78 FYA 0.623656 0.906667
79 UP5 0.62 0.896104
80 G3A 0.618557 0.897436
81 AFH 0.612245 0.886076
82 G5P 0.612245 0.897436
83 9SN 0.610526 0.85
84 GTA 0.606061 0.864198
85 YAP 0.604167 0.896104
86 FA5 0.604167 0.907895
87 TXD 0.60396 0.884615
88 XAH 0.597938 0.841463
89 XYA 0.597222 0.821918
90 ADN 0.597222 0.821918
91 RAB 0.597222 0.821918
92 48N 0.594059 0.897436
93 DAL AMP 0.593407 0.881579
94 2A5 0.593023 0.92
95 AOC 0.592593 0.8
96 4UV 0.591837 0.871795
97 NAI 0.588235 0.884615
98 NXX 0.588235 0.907895
99 NAX 0.588235 0.875
100 DND 0.588235 0.907895
101 6V0 0.588235 0.873418
102 ATR 0.586207 0.944444
103 PAP 0.586207 0.958333
104 ADP BMA 0.585106 0.894737
105 LAQ 0.584158 0.819277
106 5AS 0.583333 0.761364
107 TXE 0.582524 0.884615
108 OMR 0.582524 0.831325
109 5N5 0.581081 0.797297
110 4UU 0.58 0.871795
111 A A 0.578947 0.918919
112 7D3 0.578313 0.881579
113 AP0 0.576923 0.873418
114 A4D 0.573333 0.797297
115 5CD 0.573333 0.783784
116 JB6 0.572917 0.884615
117 4UW 0.572816 0.839506
118 A4P 0.571429 0.823529
119 CNA 0.570093 0.907895
120 7D4 0.569767 0.881579
121 ITT 0.569767 0.917808
122 A2R 0.565217 0.958904
123 M2T 0.564103 0.716049
124 YLP 0.563107 0.821429
125 139 0.560748 0.851852
126 ADJ 0.560748 0.831325
127 T5A 0.560748 0.843373
128 TAD 0.558824 0.910256
129 ATP A A A 0.555556 0.905405
130 A3P 0.552941 0.944444
131 TYM 0.552381 0.907895
132 IOT 0.551402 0.833333
133 EP4 0.551282 0.734177
134 MYR AMP 0.55102 0.797619
135 7D5 0.55 0.855263
136 A3D 0.54955 0.894737
137 GCP 0.548387 0.922078
138 YLC 0.54717 0.841463
139 YLB 0.54717 0.821429
140 UPA 0.54717 0.884615
141 NAD 0.545455 0.906667
142 COD 0.545455 0.813953
143 G5A 0.544444 0.781609
144 DTA 0.544304 0.766234
145 3DH 0.54321 0.753247
146 DZD 0.540541 0.910256
147 AHZ 0.538462 0.797619
148 MTA 0.5375 0.753247
149 3AM 0.536585 0.90411
150 A2P 0.534884 0.930556
151 TYR AMP 0.534653 0.858974
152 AR6 AR6 0.533981 0.893333
153 6AD 0.532609 0.886076
154 PPS 0.532609 0.851852
155 YLA 0.53211 0.821429
156 AMP DBH 0.529412 0.87013
157 AYB 0.527273 0.811765
158 A5A 0.526882 0.788235
159 TSB 0.526316 0.8
160 6RE 0.52381 0.7625
161 S4M 0.523256 0.670455
162 SSA 0.521277 0.802326
163 NA7 0.520408 0.959459
164 7MD 0.519231 0.864198
165 LPA AMP 0.518868 0.797619
166 BTX 0.517857 0.843373
167 NAE 0.517241 0.871795
168 52H 0.515789 0.761364
169 54H 0.515789 0.770115
170 VMS 0.515789 0.770115
171 BT5 0.513274 0.833333
172 NAQ 0.512821 0.85
173 ZAS 0.511905 0.746835
174 J7C 0.511628 0.772152
175 A3N 0.511628 0.766234
176 IMO 0.511628 0.90411
177 AV2 0.510638 0.893333
178 53H 0.510417 0.761364
179 5CA 0.510417 0.802326
180 ARU 0.510204 0.839506
181 ARG AMP 0.509434 0.831325
182 ALF ADP 3PG 0.509259 0.839506
183 AF3 ADP 3PG 0.509259 0.839506
184 LA8 ALF 3PG 0.509259 0.839506
185 M24 0.508621 0.829268
186 ZID 0.508475 0.894737
187 2AM 0.506024 0.917808
188 V3L 0.505376 0.945205
189 3AT 0.505376 0.972222
190 AVV 0.505155 0.897436
191 MAO 0.5 0.761905
192 LSS 0.5 0.764045
193 NSS 0.5 0.802326
194 DSZ 0.5 0.802326
195 EAD 0.5 0.851852
196 DSH 0.5 0.728395
197 P5A 0.5 0.747253
198 YLY 0.495726 0.811765
199 NVA LMS 0.494949 0.744444
200 5X8 0.494505 0.766234
201 DAT 0.494505 0.906667
202 7MC 0.490909 0.843373
203 LEU LMS 0.49 0.744444
204 SMM 0.489583 0.689655
205 SAM 0.489362 0.694118
206 DTP 0.489362 0.906667
207 7DD 0.488889 0.958333
208 GJV 0.488636 0.753086
209 OVE 0.488372 0.881579
210 5AD 0.486842 0.726027
211 KAA 0.485149 0.755556
212 GSU 0.485149 0.781609
213 P1H 0.483871 0.831325
214 NDE 0.483871 0.907895
215 N0B 0.483333 0.821429
216 A3G 0.482759 0.802632
217 NAD IBO 0.482456 0.848101
218 NAJ PZO 0.478632 0.82716
219 4TA 0.478261 0.809524
220 SFG 0.478261 0.753247
221 YSA 0.47619 0.781609
222 FB0 0.47619 0.827586
223 NDC 0.47619 0.85
224 7DT 0.473118 0.958333
225 A7D 0.472527 0.779221
226 NJP 0.469565 0.921053
227 FDA 0.46875 0.835294
228 A5D 0.468085 0.766234
229 SA8 0.468085 0.710843
230 MHZ 0.467391 0.701149
231 71V 0.466667 0.884615
232 0WD 0.465517 0.897436
233 G A A A 0.465517 0.85
234 6FA 0.465116 0.843373
235 GGZ 0.464646 0.804878
236 SAH 0.463158 0.746835
237 6C6 0.463158 0.883117
238 SAI 0.463158 0.7375
239 NAJ PYZ 0.46281 0.829268
240 Y3J 0.4625 0.706667
241 7D7 0.461538 0.723684
242 TXP 0.46087 0.897436
243 PO4 PO4 A A A A PO4 0.460784 0.878378
244 S7M 0.459184 0.694118
245 AMP NAD 0.459016 0.858974
246 6IA 0.458333 0.839506
247 DDS 0.458333 0.855263
248 FAD 0.458015 0.853659
249 SFD 0.458015 0.736842
250 FAS 0.458015 0.853659
251 ODP 0.456897 0.886076
252 A3S 0.456522 0.813333
253 7C5 0.453704 0.797468
254 AAT 0.453608 0.710843
255 EEM 0.453608 0.694118
256 RGT 0.45283 0.933333
257 NPW 0.452174 0.8875
258 NDP 0.452174 0.897436
259 FAY 0.451852 0.864198
260 PGS 0.451613 0.860759
261 D5M 0.449438 0.88
262 DA 0.449438 0.88
263 NEC 0.449438 0.727273
264 U A G G 0.449153 0.860759
265 2SA 0.44898 0.933333
266 NIA 0.448276 0.802469
267 NZQ 0.448276 0.910256
268 A U 0.447368 0.848101
269 A3T 0.446809 0.8
270 A A A 0.446602 0.906667
271 128 0.446429 0.758621
272 6K6 0.445545 0.905405
273 GEK 0.445545 0.740741
274 4YB 0.445455 0.764045
275 AAM 0.444444 0.944444
276 FNK 0.444444 0.806818
277 62F 0.444444 0.864198
278 Z5A 0.443548 0.761364
279 WSA 0.442478 0.790698
280 AMZ 0.44186 0.891892
281 C2R 0.44186 0.88
282 12D 0.441441 0.767442
283 XNP 0.440678 0.851852
284 RFL 0.437956 0.823529
285 N6P 0.436893 0.890411
286 62X 0.436893 0.670455
287 AIR 0.433735 0.876712
288 PLP AAD 0.433333 0.725275
289 GP3 0.43299 0.897436
290 A6D 0.432692 0.705882
291 V1N 0.431193 0.893333
292 649 0.429825 0.747253
293 GP2 0.428571 0.910256
294 NA0 0.428571 0.907895
295 GDP 0.428571 0.896104
296 0UM 0.427184 0.702381
297 DCA 0.42623 0.825581
298 ETB 0.42623 0.835294
299 GNH 0.424242 0.884615
300 NAP 0.424 0.92
301 PUA 0.422764 0.8625
302 APU 0.422414 0.871795
303 101 0.422222 0.855263
304 3AD 0.421687 0.808219
305 FA9 0.42069 0.865854
306 TAP 0.420635 0.884615
307 TM1 0.420561 0.755814
308 P5F 0.41958 0.825581
309 0T1 0.419355 0.825581
310 COA 0.419355 0.825581
311 K15 0.419048 0.686047
312 7RP 0.417582 0.902778
313 S8M 0.417476 0.7625
314 NHD 0.416667 0.881579
315 GTP 0.415842 0.896104
316 FCX 0.414062 0.797753
317 F2N 0.413793 0.816092
318 AS 0.413043 0.835443
319 7RA 0.413043 0.931507
320 G1R 0.411765 0.884615
321 SXZ 0.411215 0.714286
322 QQY 0.411111 0.794872
323 ACK 0.411111 0.837838
324 AMX 0.409449 0.835294
325 30N 0.409449 0.755319
326 CAO 0.409449 0.797753
327 J7V 0.409449 0.813953
328 COS 0.409449 0.806818
329 1DG 0.409449 0.897436
330 DG1 0.409449 0.897436
331 NAD BBN 0.408759 0.821429
332 8BR 0.408602 0.883117
333 GNP 0.407767 0.873418
334 GSP 0.407767 0.851852
335 D3Y 0.407767 0.792208
336 G2P 0.407767 0.910256
337 CC5 0.407407 0.819444
338 KB1 0.407407 0.702381
339 N01 0.406504 0.881579
340 CMX 0.40625 0.825581
341 SCO 0.40625 0.825581
342 CMP 0.404255 0.876712
343 2BA 0.404255 0.890411
344 ACO 0.403101 0.797753
345 FAM 0.403101 0.806818
346 NAD CJ3 0.402878 0.793103
347 2VA 0.402062 0.779221
348 3NZ 0.401869 0.78481
349 26A 0.4 0.74359
350 HAX 0.4 0.806818
351 QQX 0.4 0.78481
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2PVF; Ligand: ACP; Similar sites found: 319
This union binding pocket(no: 1) in the query (biounit: 2pvf.bio1) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4MV1 ADP 0.006745 0.42488 1.49701
2 3PQB VGP 0.01141 0.40121 1.49701
3 1IA9 ANP 0.00007038 0.47647 1.78571
4 5MW8 ATP 0.00001376 0.53612 1.79641
5 3ETH ATP 0.0005935 0.45956 1.79641
6 3V4S ATP 0.00101 0.44907 1.79641
7 3V4S ADP 0.005483 0.43279 1.79641
8 3AKK ADP 0.00006247 0.49921 1.84615
9 5IH1 GDP 0.03848 0.40331 1.98676
10 5IH1 6BQ 0.04048 0.40219 1.98676
11 3WO0 ALA 0.005615 0.43455 2.09581
12 2GQS ADP 0.0004857 0.45457 2.1097
13 2GQR ADP 0.0007703 0.4457 2.1097
14 3VPD ANP 0.003879 0.42253 2.13523
15 3B6R CRN 0.0002092 0.50466 2.39521
16 3WVR AMP 0.0006144 0.4457 2.39521
17 4PU5 ANP 0.0009573 0.41366 2.39521
18 1M0W ANP 0.003714 0.41109 2.39521
19 2R7K AMZ 0.01295 0.40763 2.39521
20 1ZB6 GST 0.01746 0.4028 2.60586
21 4OCJ NDG 0.0002349 0.50093 2.69461
22 4OCV ANP 0.0001663 0.48014 2.69461
23 4U98 ACP 0.0002656 0.46618 2.69461
24 2YW2 ATP 0.001458 0.41554 2.69461
25 4CTA ATP 0.01517 0.40023 2.69461
26 1OBD ATP 0.00003035 0.49279 2.94118
27 2IF8 ADP 0.0002669 0.49605 2.99401
28 2VPQ ANP 0.0002901 0.47572 2.99401
29 3DNT ATP 0.00116 0.45006 2.99401
30 2Q7D ANP 0.007571 0.41572 2.99401
31 4KOT CE3 0.02642 0.40296 3.08642
32 1T36 ADP 0.009528 0.4125 3.29341
33 1PK8 ATP 0.0006575 0.41147 3.29341
34 3TII ANP 0.004085 0.40015 3.29341
35 3Q8G PEE 0.02021 0.42038 3.4375
36 1AUX AGS 0.0006583 0.44225 3.53698
37 3VPC ADP 0.0004257 0.42985 3.5461
38 3VPB ADP 0.0001929 0.42572 3.5461
39 5I35 ANP 0.00001547 0.52086 3.59281
40 3I0O ADP 0.0002162 0.48731 3.59281
41 3TPV ADE 0.001333 0.42347 3.59281
42 1IOW ADP 0.005001 0.43352 3.59477
43 1IOW PHY 0.005001 0.43352 3.59477
44 2V2V V12 0.03042 0.40273 3.69004
45 2AQX ATP 0.004771 0.41845 3.80623
46 5A89 ADP 0.03143 0.40202 3.84615
47 5VZ0 ADP 0.0002033 0.47133 3.89222
48 4XYM A12 0.0005909 0.45544 3.91304
49 2R3A SAM 0.005526 0.40986 4
50 2FXD DR7 0.01523 0.40561 4.0404
51 5CKW ANP 0.000009351 0.50838 4.19162
52 1EHI ADP 0.002825 0.42494 4.19162
53 3OCP CMP 0.008842 0.4105 4.31655
54 4OUC 5ID 0.000000843 0.56782 4.48179
55 2PYW ADP 0.000004039 0.55529 4.49102
56 3ORQ ADP 0.0005602 0.4312 4.49102
57 5TDF ADP 0.006373 0.41093 4.49102
58 1I7L ATP 0.0007 0.41491 4.53074
59 3MTX PGT 0.01867 0.40385 4.63576
60 3HAV ATP 0.0007834 0.40908 4.68227
61 2BKK ADP 0.0001951 0.46069 4.73373
62 3X01 AMP 0.001449 0.46305 4.79042
63 2VQD AP2 0.0003727 0.46662 5.08982
64 4AZW ATP 0.000623 0.45655 5.08982
65 3TDV GDP 0.00002164 0.50485 5.22876
66 1GSA ADP 0.0001848 0.48465 5.37975
67 1ZP9 ATP 0.000002047 0.55184 5.42636
68 1ZTH ADP 0.000001131 0.54398 5.42636
69 5W2I ADP 0.0007196 0.45958 5.44747
70 5W2I I3P 0.0007196 0.45958 5.44747
71 4FE2 ADP 0.00535 0.4165 5.4902
72 3UDZ ADP 0.000007728 0.53991 5.98802
73 4AXD ANP 0.00006877 0.5266 5.98802
74 4ANW O92 0.0005167 0.47769 5.98802
75 1TQP ATP 0.000003507 0.48994 6.28743
76 4OYA 1VE 0.009705 0.44206 6.28743
77 2QK4 ATP 0.00142 0.41161 6.28743
78 2BO9 VAL 0.01512 0.40792 6.30631
79 4GYI ADP 0.00003677 0.51697 6.58683
80 3VOT ADP 0.001677 0.41821 7.18563
81 4ZS4 ATP 0.00002145 0.52003 7.49186
82 5U98 1KX 0.04572 0.40496 8.08081
83 2HGS ADP 0.003555 0.42604 8.08383
84 4LRJ ANP 0.000002692 0.55448 8.28402
85 1W2D ADP 0.0007412 0.46183 8.30189
86 3PDT ADP 0.000193 0.47777 8.36364
87 4YNM SAM 0.007318 0.4044 8.40708
88 4NG2 OHN 0.004527 0.41765 8.84956
89 4LO2 GAL BGC 0.001675 0.46333 9.52381
90 5DMZ ADP 0.00000002508 0.6285 9.88024
91 3RE4 TO1 0.00005792 0.51454 10.0775
92 4XMF HSM 0.008595 0.42654 10.3261
93 4CYI ATP 0.00000332 0.55913 10.7784
94 3Q60 ATP 0.000001706 0.56325 11.976
95 5IQD RIO 0.00004792 0.53415 12.1311
96 5IQD GNP 0.00004472 0.53415 12.1311
97 4Y0X ADP 0.0000003228 0.58635 13.4731
98 3K5I ADP 0.001111 0.42139 14.0719
99 4O4F IHP 0.002129 0.44128 14.1129
100 4O4F ATP 0.001963 0.44128 14.1129
101 4OAV ACP 0.000000003028 0.68503 14.3713
102 4WW7 AMP 0.000001916 0.5726 14.5594
103 5K2M ADP 0.00176 0.44176 15.0943
104 5UKL SIX 0.00000002286 0.67396 15.5689
105 3PVW QRX 0.0000000434 0.53955 15.5689
106 2PZI AXX 0.00001477 0.53537 15.8683
107 5C4L 4XR 0.00007928 0.51455 15.8879
108 5C4L SIS 0.0009021 0.46481 15.8879
109 5C1P DAL DAL 0.01061 0.40742 16.0131
110 5C1P ADP 0.003636 0.40674 16.0131
111 3FHR P4O 0.000001321 0.54354 17.0659
112 4O1P ANP 0.000000001987 0.69712 17.6647
113 1O9U ADZ 0.0000001807 0.6802 17.9641
114 3F7Z 34O 0.00000005741 0.63202 17.9641
115 4NM5 ADP 0.00005572 0.54458 17.9641
116 2JLD AG1 0.000000008478 0.50994 17.9641
117 4L9I 8PR 0.00000001386 0.65578 18.254
118 4XH0 ADP 0.000003355 0.59766 18.2635
119 4F9C 0SX 0.0000001155 0.61502 20.6587
120 4IX4 ADP 0.000004353 0.55382 21.5569
121 3M2W L8I 0.000000002295 0.66176 21.7391
122 3LQV ADE 0.006642 0.42385 23.0769
123 5GZ9 ANP 0.000000007349 0.68539 23.6066
124 3E8N ATP 0.000000003403 0.45581 24.6334
125 3E8N VRA 0.000000003403 0.45581 24.6334
126 4CRL C1I 0.0000003908 0.62724 25.1232
127 4YZC STU 0.000000003347 0.73199 25.1497
128 1PHK ATP 0.0000000001788 0.74783 26.5101
129 2WU6 DKI 0.00000000233 0.61292 26.9461
130 3C0G 3AM 0.00000002208 0.62125 27.2455
131 5X8I SQZ 0.00000000264 0.69162 28.1437
132 4UX9 ANP 0.000000001772 0.64471 28.1437
133 4WHZ 3NL 0.000001591 0.6186 28.4431
134 3E7O 35F 0.00000691 0.56627 28.4431
135 3TTI KBI 0.00000002736 0.53607 28.4431
136 3PTG 932 0.000001927 0.52635 28.4431
137 4IDT T28 0.000000009653 0.66274 29.2135
138 4Y85 499 0.000009673 0.52988 29.2169
139 4Q5H ANP 0.000002261 0.5461 29.3103
140 2F2U M77 0.00000001739 0.6822 29.3413
141 2R5T ANP 0.0000000191 0.5903 29.6407
142 4IZY 1J2 0.0000003351 0.55826 29.6407
143 3PE2 E1B 0.000001473 0.61752 29.6736
144 3KN5 ANP 0.0000006011 0.56225 29.8462
145 3V8S 0HD 0.00000002542 0.64412 29.9401
146 2B9H ADP 0.000000001554 0.7057 30.2395
147 2B9J ADP 0.000000001075 0.70495 30.2395
148 2B9F ADP 0.000000001454 0.70317 30.2395
149 4H3P ANP 0.000000002161 0.6955 30.2395
150 2B9I ADP 0.000000001059 0.6867 30.2395
151 5T8O 76Z 0.00000001929 0.60082 30.2395
152 1Q8Y ADP 0.000000000676 0.72566 30.5389
153 4WNK 453 0.000000003758 0.71568 30.5389
154 4H3Q ANP 0.000000007197 0.68581 30.5389
155 5LXC 7AA 0.000000004854 0.66277 30.5389
156 1Q8Y ADE 0.00000003367 0.58924 30.5389
157 4OH4 ANP 0.00000001394 0.63926 30.6306
158 3UIM ANP 0.0000001567 0.61258 30.6748
159 5LPZ ADP 0.000000003137 0.68828 30.7229
160 4IJP 1EH 0.00000000433 0.68927 30.8383
161 4YLL 4E3 0.00000009694 0.63429 30.8383
162 5AWM ANP 0.000000139 0.58202 30.8383
163 4BTK DTQ 0.000008433 0.53544 30.8383
164 2YAB AMP 0.000000001825 0.70257 31.1377
165 5EFQ ADP 0.000000005068 0.679 31.1377
166 5VCV 1N1 0.000000003686 0.70218 31.1897
167 3SLS ANP 0.0000000024 0.6246 31.25
168 3TKI S25 0.000000002097 0.76724 31.2694
169 2CSN CKI 0.000000004852 0.70252 31.3131
170 4EUU BX7 0.00000001426 0.68084 31.348
171 2HY0 306 0.0000000732 0.64236 31.3665
172 5BYZ 4WE 0.00000002466 0.67971 31.4371
173 4DC2 ADE 0.00000002956 0.53337 31.4371
174 2ZV2 609 0.0000001047 0.64508 31.5436
175 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.0000000005477 0.80102 31.7365
176 2JDR L20 0.0000000005477 0.80102 31.7365
177 5LI1 ANP 0.0000000009237 0.72309 31.7365
178 4NST ADP 0.00000001541 0.65747 31.7365
179 5LI9 ACP 0.0000001404 0.58226 31.7365
180 2QLU ADE 0.0000001402 0.67835 31.8471
181 5BVE 4VG 0.0000000429 0.71109 32.0359
182 3TXO 07U 0.00000002829 0.63037 32.0359
183 2XK9 XK9 0.00000004186 0.6774 32.2981
184 2V7O DRN 0.000000001954 0.63483 32.3353
185 5M06 ADP 0.000009058 0.52304 32.6087
186 2RIO ADP 0.0000000001055 0.74958 32.6347
187 1CM8 ANP 0.000003198 0.55116 32.6347
188 5W4W 9WG 0.00002182 0.54093 32.9305
189 4KBA 1QM 0.0001352 0.41764 32.9305
190 3MVH WFE 0.00000000009426 0.79076 32.9341
191 3OFM 4B0 0.000001004 0.55467 33.1429
192 3HMO STU 0.00000004539 0.63297 33.3333
193 2WEL K88 0.0000003258 0.51831 33.3333
194 4NFN 2KC 0.00003337 0.50607 33.3333
195 4LH7 1X8 0.01401 0.40444 33.3333
196 2PVN P63 0.00000002948 0.52372 33.5227
197 2VZ6 FEF 0.00000005928 0.64661 33.5463
198 4UAL 3FV 0.0000001211 0.61757 33.8323
199 3QCQ 3Q0 0.00000004475 0.73121 33.9744
200 5LVP ATP 0.000000001939 0.66735 34.0836
201 3ORK AGS 0.00000003575 0.54959 34.0836
202 5EKO N17 0.0001532 0.48837 34.1317
203 3HZT J60 0.000000143 0.57569 34.4311
204 5LPB ADP 0.00000004516 0.59749 34.4595
205 4L3L 5FI 0.00000001812 0.68364 34.5395
206 1OUK 084 0.00001349 0.61017 34.7305
207 3GNI ATP 0.00000003461 0.59134 34.7305
208 3SXF BK5 0.0000002429 0.639 35.3293
209 4LOO SB4 0.00006749 0.49518 35.3293
210 5C03 AGS 0.000005096 0.54519 35.6287
211 3GC8 B45 0.000003973 0.50458 35.6287
212 4AUA 4AU 0.000001331 0.56801 36.1564
213 2VN9 GVD 0.000000007139 0.60739 36.2126
214 3IGO ANP 0.0000001552 0.55757 36.2275
215 5A6N U7E 0.00000005706 0.63552 36.3958
216 2YAK OSV 0.000000002874 0.72115 36.4912
217 2BPM 529 0.00000000628 0.43661 36.5696
218 3CY2 MB9 0.00000005534 0.64539 36.6242
219 4CFU 2WC 0.00000000444 0.68798 36.6337
220 4I94 ANP 0.00000009891 0.618 36.6667
221 5JZJ AN2 0.00000000004012 0.76817 36.7003
222 4OTH DRN 0.0000000002661 0.74762 36.8263
223 5TA6 79D 0.000004159 0.56886 36.8715
224 4BCQ TJF 0.0000001383 0.57838 36.8771
225 4BCM T7Z 0.0000004631 0.53513 36.8771
226 4BCN T9N 0.000000004211 0.69994 37
227 3GC0 AMP 0.0000006735 0.56101 37.0821
228 1XJD STU 0.000000006601 0.67753 37.1257
229 3DLS ADP 0.00000005764 0.61716 37.1257
230 1ZY5 ANP 0.000002956 0.55268 37.2937
231 5LMK 6ZK 0.00001302 0.51601 37.3737
232 4WB6 ATP 0.000000001395 0.72758 37.4251
233 1V0O INR 0.000000004458 0.6422 37.5
234 3ZRM ZRM 0.000002557 0.55853 37.5
235 4JDI ANP 0.0000000004545 0.6639 37.7246
236 4WB7 ATP 0.000000008523 0.4931 37.7246
237 5UIU 8CG 0.000000009059 0.69776 37.7709
238 2XMY CDK 0.000000779 0.6506 37.9195
239 4AU8 Z3R 0.0000002673 0.62571 38.1757
240 2GU8 796 0.000000006461 0.74581 38.3234
241 1RE8 BD2 0.000000004392 0.74154 38.3234
242 2QCS ANP 0.0000000008525 0.73748 38.3234
243 3FHI ANP 0.000000001179 0.73097 38.3234
244 3IDB ANP 0.0000000007895 0.72959 38.3234
245 1UNH IXM 0.00000001233 0.63058 38.6986
246 3O0G 3O0 0.0000001266 0.61325 38.6986
247 4D2S DYK 0.0000001161 0.58921 38.7324
248 4QTB 38Z 0.000000008117 0.69748 38.9222
249 4BHN BH9 0.00000001952 0.65977 38.9222
250 1U5R ATP 0.0000000006147 0.71569 39.2216
251 4N70 2HX 0.00000001608 0.71709 39.3293
252 3FC2 IBI 0.0003132 0.51963 39.403
253 4X7Q 3YR 0.000000001407 0.67975 39.4231
254 2A19 ANP 0.000000006513 0.7025 39.4366
255 5VC5 96M 0.00000004011 0.6626 39.4464
256 5KO1 6UY 0.00000003931 0.63574 39.576
257 4M69 ANP 0.000001315 0.57727 39.576
258 5IH9 6BF 0.00000005282 0.67257 39.8204
259 5MY8 RXZ 0.0000000134 0.67933 40
260 4JR7 GNP 0.000000005875 0.67614 40
261 4C2V YJA 0.0000001436 0.64147 40
262 2PUL ACP 0.000011 0.52741 40
263 4BFM ANP 0.0000000004321 0.73443 40.1198
264 4U44 3D9 0.0000007264 0.58289 40.3614
265 5EYK 5U5 0.0000001091 0.6424 40.5797
266 3ALN ANP 0.0000001459 0.57053 40.6728
267 4C2W ANP 0.000000001283 0.65696 40.8602
268 4Y8D 49J 0.000001421 0.55392 41.018
269 4WNP 3RJ 0.0000000006079 0.68536 41.115
270 5JGA 6KC 0.000000009481 0.7016 41.2698
271 5AX9 4KT 0.0000008564 0.57971 41.5584
272 4G31 0WH 0.000005306 0.42249 42.1405
273 2WEI VGG 0.00001898 0.50899 42.1603
274 5HVJ ANP 0.00000001083 0.73024 42.2222
275 5DH3 5BS 0.00000002369 0.65597 42.2222
276 5DRB 5FJ 0.000003184 0.60108 42.268
277 2F57 23D 0.000001292 0.55864 42.2713
278 2Z7R STU 0.0000000002752 0.65848 42.3676
279 5N87 N66 0.000000008814 0.70974 42.492
280 2X4Z X4Z 0.0000003888 0.62927 42.5676
281 3KMW ATP 0.000008308 0.5328 42.8044
282 4I6H 1C8 0.00001671 0.5083 42.8571
283 4A4X JUP 0.0000000771 0.64691 43.0108
284 3H9R TAK 0.000001942 0.51939 43.0303
285 4NW6 2NS 0.000000001079 0.536 43.0341
286 4FG8 ATP 0.0000000006065 0.72779 43.1746
287 5USZ SKE 0.0000008042 0.60205 43.2526
288 5DBX ANP 0.0000007659 0.55818 43.2927
289 3AQV TAK 0.00004787 0.50183 43.4783
290 5HQ0 LZ9 0.000000008224 0.6767 44.0397
291 4USF 6UI 0.0000303 0.52267 44.0789
292 4QMN DB8 0.0000001885 0.64617 44.5161
293 2WQN ADP 0.000001769 0.57815 44.8387
294 3GGF GVD 0.000000008354 0.67554 45.1827
295 4FL3 ANP 0.0000000005024 0.6504 45.2096
296 4WOV 3SM 0.00003362 0.51878 45.7413
297 4Y93 746 0.000001819 0.58106 45.8084
298 5G1X ADP 0.0000000001442 0.74357 45.9649
299 5L8L ADP 0.000000001646 0.65393 45.9649
300 5DEY 59T 0.0000006011 0.64475 46.1279
301 5HES 032 0.0000003703 0.60498 46.2541
302 5LXM ADP 0.00000000008993 0.75265 46.2898
303 3LXK MI1 0.00000000141 0.57622 46.4832
304 3DAK ANP 0.00000001566 0.66317 46.5517
305 4G17 0VN 0.00004862 0.49068 46.6667
306 2IO8 ADP 0.0002339 0.48197 46.6667
307 4R78 AMP 0.0001402 0.45328 46.6667
308 1Y57 MPZ 0.00000005089 0.64706 46.7066
309 2H8H H8H 0.00000009353 0.62257 46.7066
310 4KS7 X4Z 0.0000004539 0.53084 46.9178
311 2J7T 274 0.00001825 0.54279 47.6821
312 4YZN 4K5 0.0000000008736 0.72759 47.7352
313 5UOX 8GY 0.000000008655 0.679 48.3395
314 1VJY 460 0.000000006021 0.71092 48.5149
315 5EW9 5VC 0.0000006939 0.67876 48.7085
316 3VRY B43 0.0000007931 0.49843 48.8024
317 3E5A VX6 0.00000003296 0.54939 48.8806
318 5MJA 7O3 0.000002157 0.54904 49.1803
319 4E93 GUI 0.00000002488 0.49902 49.4012
320 3LXN MI1 0.0000000004462 0.7338 50
321 5CEO 50D 0.000001465 0.56931 50
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