Receptor
PDB id Resolution Class Description Source Keywords
2PSM 2.19 Å NON-ENZYME: IMMUNE CRYSTAL STRUCTURE OF INTERLEUKIN 15 IN COMPLEX WITH INTERLEUKIN 15 RECEPTOR ALPHA MUS MUSCULUS CYTOKINE GLYCOPROTEIN SECRETED ALTERNATIVE SPLICING ENDOPLASMIC RETICULUM GOLGI APPARATUS MEMBRANE NUCLEUS PHOSPHORYLATION RECEPTOR SUSHI TRANSMEMBRANE STRUCTURALGENOMICS NPPSFA NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE RSGI
Ref.: CRYSTAL STRUCTURE OF THE INTERLEUKIN-15{MIDDLE DOT}INTERLEUKIN-15 RECEPTOR {ALPHA} COMPLEX: INSIGHTS INTO TRANS AND CIS PRESENTATION J.BIOL.CHEM. V. 282 37191 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BAM B:115;
Valid;
none;
submit data
121.16 C7 H9 N2 c1ccc...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2PSM 2.19 Å NON-ENZYME: IMMUNE CRYSTAL STRUCTURE OF INTERLEUKIN 15 IN COMPLEX WITH INTERLEUKIN 15 RECEPTOR ALPHA MUS MUSCULUS CYTOKINE GLYCOPROTEIN SECRETED ALTERNATIVE SPLICING ENDOPLASMIC RETICULUM GOLGI APPARATUS MEMBRANE NUCLEUS PHOSPHORYLATION RECEPTOR SUSHI TRANSMEMBRANE STRUCTURALGENOMICS NPPSFA NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE RSGI
Ref.: CRYSTAL STRUCTURE OF THE INTERLEUKIN-15{MIDDLE DOT}INTERLEUKIN-15 RECEPTOR {ALPHA} COMPLEX: INSIGHTS INTO TRANS AND CIS PRESENTATION J.BIOL.CHEM. V. 282 37191 2007
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 199 families.
1 2PSM - BAM C7 H9 N2 c1ccc(cc1)....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 65 families.
1 2PSM - BAM C7 H9 N2 c1ccc(cc1)....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 43 families.
1 2PSM - BAM C7 H9 N2 c1ccc(cc1)....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: BAM; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 BAM 1 1
2 BEN 0.52 0.941176
3 PBZ 0.428571 0.85
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2PSM; Ligand: BAM; Similar sites found: 14
This union binding pocket(no: 1) in the query (biounit: 2psm.bio2) has 4 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2YLD CMO 0.00003599 0.43066 4.13223
2 1XRO LEU 0.00009411 0.50183 4.95868
3 1YSL COA 0.00000213 0.49198 7.43802
4 2WYA HMG 0.00005908 0.55965 8.97436
5 3SHZ 5CO 0.00001521 0.55105 9.09091
6 5KD8 TNR 0.00002849 0.48812 9.09091
7 4R6W PC 0.009289 0.42804 9.09091
8 2C9E PID 0.002398 0.43601 10.2564
9 2P8U COA 0.00006156 0.50052 14.1026
10 4OHU 2TK 0.0003119 0.43282 14.1026
11 4OHU NAD 0.0003119 0.43282 14.1026
12 4PJT 2YQ 0.003829 0.40745 14.1026
13 2DYR PGV 0.004908 0.41984 14.876
14 3WCA FPS 0.000006454 0.43823 24.359
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