Receptor
PDB id Resolution Class Description Source Keywords
2PP3 2.2 Å EC: 4.-.-.- CRYSTAL STRUCTURE OF L-TALARATE/GALACTARATE DEHYDRATASE MUTA LIGANDED WITH MG AND L-GLUCARATE SALMONELLA TYPHIMURIUM ENOLASE SUPERFAMILY L-TALARATE/GALACTARATE DEHYDRATASE LYA
Ref.: EVOLUTION OF ENZYMATIC ACTIVITIES IN THE ENOLASE SUPERFAMILY: L-TALARATE/GALACTARATE DEHYDRATASE FRO SALMONELLA TYPHIMURIUM LT2. BIOCHEMISTRY V. 46 9564 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
LGT A:501;
B:502;
C:503;
Valid;
Valid;
Valid;
none;
none;
none;
submit data
210.139 C6 H10 O8 [C@@H...
MG A:901;
B:902;
C:903;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2PP3 2.2 Å EC: 4.-.-.- CRYSTAL STRUCTURE OF L-TALARATE/GALACTARATE DEHYDRATASE MUTA LIGANDED WITH MG AND L-GLUCARATE SALMONELLA TYPHIMURIUM ENOLASE SUPERFAMILY L-TALARATE/GALACTARATE DEHYDRATASE LYA
Ref.: EVOLUTION OF ENZYMATIC ACTIVITIES IN THE ENOLASE SUPERFAMILY: L-TALARATE/GALACTARATE DEHYDRATASE FRO SALMONELLA TYPHIMURIUM LT2. BIOCHEMISTRY V. 46 9564 2007
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 38 families.
1 2PP1 - LLH C5 H9 N O7 [C@H]([C@H....
2 2PP3 - LGT C6 H10 O8 [C@@H]([C@....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 35 families.
1 2PP1 - LLH C5 H9 N O7 [C@H]([C@H....
2 2PP3 - LGT C6 H10 O8 [C@@H]([C@....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 27 families.
1 2PP1 - LLH C5 H9 N O7 [C@H]([C@H....
2 2PP3 - LGT C6 H10 O8 [C@@H]([C@....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: LGT; Similar ligands found: 12
No: Ligand ECFP6 Tc MDL keys Tc
1 LGT 1 1
2 GAE 1 1
3 RAT 0.666667 1
4 LFC 0.636364 0.777778
5 TAR 0.588235 1
6 SRT 0.588235 1
7 TLA 0.588235 1
8 REL 0.56 0.941176
9 FIX 0.444444 0.941176
10 2OP 0.421053 0.611111
11 LAC 0.421053 0.611111
12 IPM 0.416667 0.8
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2PP3; Ligand: LGT; Similar sites found: 512
This union binding pocket(no: 1) in the query (biounit: 2pp3.bio2) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1V6A TRE 0.003583 0.41889 0.903614
2 3MPI GRA 0.02574 0.40317 1.00756
3 2BII MTV 0.005591 0.40052 1.25628
4 1REO FAD 0.0008399 0.45276 1.50754
5 2YYJ 4HP 0.007195 0.44091 1.50754
6 2YYJ FAD 0.007195 0.44091 1.50754
7 1KOL NAD 0.003724 0.42349 1.50754
8 3I28 34N 0.01386 0.4099 1.50754
9 1Z45 UPG 0.002184 0.40835 1.50754
10 4C6F NCD 0.0002874 0.42133 1.52672
11 4QCK ASD 0.0005391 0.44222 1.5544
12 1P4C FMN 0.02447 0.40148 1.57895
13 2R5T ANP 0.002644 0.40919 1.60858
14 1PL6 572 0.005837 0.41229 1.68539
15 4I9A NCN 0.004909 0.41012 1.73611
16 1CBF SAH 0.00185 0.40664 1.75439
17 4AT0 FAD 0.0005547 0.46847 1.75879
18 4AXD ANP 0.002549 0.43005 1.75879
19 4G1V FAD 0.00159 0.42753 1.75879
20 1TFZ 869 0.001682 0.41453 1.75879
21 4ARF IP8 GLY PRO ALA 0.002455 0.40223 1.77665
22 3ZV6 4HB 0.006219 0.42069 1.77936
23 4JHG ZEA 0.001791 0.40715 1.78571
24 1GAD NAD 0.006054 0.40381 1.81818
25 2GDZ NAD 0.007153 0.40512 1.87266
26 2RGH FAD 0.005603 0.4206 1.92644
27 2J7T 274 0.001297 0.43242 1.98676
28 1SB8 UD2 0.01488 0.4125 1.98864
29 4W97 UCA 0.005206 0.40329 2
30 3Q3C NAD 0.005851 0.42948 2.00669
31 1TIW TFB 0.0008335 0.45175 2.01005
32 1TIW FAD 0.0008335 0.45175 2.01005
33 1Q0H NDP 0.002241 0.44346 2.01005
34 3PC3 P1T 0.0005964 0.43314 2.01005
35 4O8A FAD 0.001497 0.43286 2.01005
36 4LCQ URQ 0.001273 0.43274 2.01005
37 1Q0H FOM 0.006635 0.42226 2.01005
38 1RKD ADP 0.006507 0.40923 2.01005
39 1RKD RIB 0.006507 0.40923 2.01005
40 1MG1 MAL 0.002977 0.40908 2.01005
41 2R0N TGC 0.007355 0.45454 2.03046
42 1JUV NDP 0.00506 0.40679 2.07254
43 3QUR ADP 0.002487 0.42428 2.0979
44 3QUR FM4 0.002487 0.42428 2.0979
45 1G0N NDP 0.001036 0.44796 2.12014
46 1G0N PHH 0.006219 0.41974 2.12014
47 1IUP ALQ 0.004256 0.41387 2.12766
48 1LDM NAD 0.0404 0.40044 2.12766
49 1NHZ 486 0.001104 0.42514 2.14286
50 1EYE PMM 0.001609 0.40154 2.14286
51 4LWA Q13 0.003351 0.42859 2.20386
52 3KO8 NAD 0.00195 0.42972 2.24359
53 4A8H PUW 0.004897 0.41216 2.25352
54 4FWE FAD 0.0002245 0.48044 2.26131
55 1H82 GZZ 0.001077 0.46582 2.26131
56 1H82 FAD 0.0009481 0.46582 2.26131
57 4L7I SAM 0.0005255 0.42867 2.26131
58 3T1A 5MA 0.0006114 0.42854 2.26131
59 4MZ7 DTP 0.002861 0.42056 2.26131
60 3ULK NDP 0.001725 0.41792 2.26131
61 2YPO PHE 0.003985 0.41498 2.26131
62 2CFU 1DB 0.003574 0.40434 2.26131
63 3IAE D7K 0.00875 0.40297 2.26131
64 4MZ7 DGT 0.008748 0.40172 2.26131
65 1XLI GLT 0.0011 0.44079 2.28426
66 3OCZ SRA 0.0006739 0.42475 2.29008
67 1MDZ DCS 0.004418 0.41705 2.29008
68 1MDZ PLP 0.006783 0.40852 2.29008
69 1B4P GPS 0.001346 0.41603 2.30415
70 1R37 NAD 0.006227 0.41236 2.30548
71 4QDC ASD 0.001702 0.42564 2.30769
72 4LSJ LSJ 0.001072 0.42371 2.32558
73 4BX7 B4F 0.005857 0.40436 2.34375
74 3ZPG 5GP 0.005927 0.43621 2.35602
75 2F01 BTQ 0.002894 0.45037 2.3622
76 2F01 BTN 0.002894 0.45037 2.3622
77 3PJU C2E 0.001524 0.4267 2.40964
78 1FP1 HCC 0.003372 0.40146 2.41935
79 3FPZ AHZ 0.006533 0.44168 2.45399
80 1HDR NAD 0.00821 0.42096 2.45902
81 3HY3 10F 0.0007191 0.43395 2.46305
82 3EE4 MYR 0.002702 0.40884 2.47678
83 1T26 GBD 0.03468 0.41513 2.48447
84 1T26 NAI 0.03468 0.41513 2.48447
85 2YVF FAD 0.00456 0.4392 2.51256
86 2YVF NAD 0.005582 0.43615 2.51256
87 2ZX7 ZX7 0.001982 0.42743 2.51256
88 1HV9 UD1 0.005976 0.42324 2.51256
89 3WO0 ADP 0.003843 0.42295 2.51256
90 3WO0 ALA 0.003843 0.42295 2.51256
91 1R89 CTP 0.002308 0.40319 2.51256
92 4QDF 30Q 0.001083 0.43314 2.53807
93 2VAR KDG 0.000193 0.43309 2.55591
94 1IYE PGU 0.002921 0.42155 2.589
95 2GYI HYA 0.005879 0.43652 2.59067
96 2QTR NXX 0.008186 0.4041 2.6455
97 2H6T IVA VAL VAL STA ALA STA 0.003057 0.40096 2.64706
98 2ZI8 SDT 0.004762 0.41063 2.66667
99 1V35 NAI 0.0004207 0.46713 2.73556
100 1KW6 BPY 0.02472 0.40849 2.73973
101 1H6C NDP 0.0005243 0.4586 2.76382
102 1ZK7 FAD 0.002239 0.44164 2.76382
103 2YB9 HA0 0.001593 0.43042 2.76382
104 2TPL HPP 0.001641 0.42388 2.76382
105 1LCP PLU 0.002446 0.41729 2.76382
106 1E5F PLP 0.001417 0.41081 2.76382
107 3AXB PRO 0.0123 0.40862 2.76382
108 1DLJ UGA 0.01736 0.4082 2.76382
109 1DLJ NAI 0.01736 0.4082 2.76382
110 1TUF AZ1 0.003882 0.40811 2.76382
111 3AXB FAD 0.0104 0.40676 2.76382
112 4KCF AKM 0.004694 0.40338 2.76382
113 1ECC PCP 0.004914 0.40263 2.76382
114 1A27 NAP 0.0007418 0.44328 2.76817
115 1A27 EST 0.002037 0.40514 2.76817
116 3JYN NDP 0.001965 0.43088 2.76923
117 1UJ2 C5P 0.006421 0.40137 2.77778
118 1WVG CXY 0.0009245 0.42802 2.78552
119 1WVG APR 0.002065 0.42009 2.78552
120 4CMF PXG 0.01306 0.41336 2.79503
121 4N02 FNR 0.01134 0.41744 2.80112
122 3WAS BGC BMA 0.005853 0.41103 2.82051
123 1RYD NDP 0.003117 0.42769 2.84238
124 4BG1 OGA 0.001088 0.42348 2.84238
125 2EFJ SAH 0.002017 0.40751 2.86458
126 2WA4 069 0.0001449 0.44957 2.86533
127 1IM8 SAI 0.00116 0.42245 2.86885
128 2OYS FMN 0.003422 0.40504 2.89256
129 3MAG 3MA 0.01112 0.43062 2.9316
130 1T8U UAP SGN IDS SGN 0.001005 0.44848 2.94118
131 4NES UD1 0.0007292 0.42574 2.94118
132 1T8U A3P 0.002253 0.40986 2.94118
133 2HGZ PBF 0.006245 0.4003 2.94118
134 1Z44 NPO 0.0246 0.4208 2.95858
135 2WM1 13P 0.0002689 0.40949 2.97619
136 3LZW NAP 0.01721 0.41331 3.01205
137 3LZW FAD 0.01055 0.40752 3.01205
138 3MTW M3R 0.0003032 0.43485 3.01508
139 4BJZ FAD 0.0135 0.42457 3.01508
140 4BJZ P3A 0.0135 0.42457 3.01508
141 4CCN OGA 0.00003279 0.42209 3.01508
142 1UMP SQA 0.002134 0.41955 3.01508
143 3HAZ FAD 0.004103 0.4158 3.01508
144 1Q7E MET 0.003975 0.4108 3.01508
145 2BJK NAD 0.01848 0.40889 3.01508
146 4IOK ADP 0.005909 0.40421 3.01508
147 4I71 AGV 0.000499 0.43176 3.0303
148 3PFG SAM 0.004935 0.42283 3.04183
149 3PFG TLO 0.004935 0.42283 3.04183
150 1SOW NAD 0.01064 0.40085 3.04878
151 1Y42 TYR 0.0005079 0.44758 3.06122
152 1X1T NAD 0.03272 0.40777 3.07692
153 2TPS TPS 0.01922 0.40023 3.0837
154 2XK9 XK9 0.0003219 0.46312 3.10559
155 1X8X TYR 0.0001447 0.43057 3.10559
156 5YAS FAC 0.0008956 0.40693 3.11284
157 3IU9 T07 0.01891 0.41157 3.125
158 3ICC NAP 0.001874 0.4304 3.13725
159 1QJC PNS 0.01802 0.40936 3.16456
160 2ZJ3 G6P 0.002727 0.40681 3.2
161 2YGN PCF 0.003075 0.41796 3.20513
162 1E4E PHY 0.002027 0.40522 3.207
163 1GV0 NAD 0.001574 0.43062 3.22581
164 1ML4 PAL 0.002422 0.41502 3.24675
165 2PNZ UDP 0.001291 0.42783 3.2491
166 2QQ0 ADP 0.001243 0.436 3.26087
167 2QQ0 TMP 0.001243 0.436 3.26087
168 2ALG DAO 0.0007359 0.42976 3.26087
169 2ALG HP6 0.0007359 0.42976 3.26087
170 2QQ0 THM 0.003877 0.41408 3.26087
171 2QQ0 ANP 0.004542 0.41408 3.26087
172 2XVE FAD 0.003976 0.44243 3.26633
173 1JIL 485 0.0003593 0.43917 3.26633
174 1PJ6 FOL 0.003524 0.43169 3.26633
175 3FC4 EDO 0.008053 0.42443 3.26633
176 3OND ADN 0.008351 0.41984 3.26633
177 3OND NAD 0.008351 0.41984 3.26633
178 1WDA BAG 0.001936 0.41844 3.26633
179 2XVF FAD 0.005863 0.41672 3.26633
180 2XCG XCG 0.003735 0.41607 3.26633
181 2CKM AA7 0.01213 0.40795 3.26633
182 1OYB HBA 0.005301 0.40602 3.26633
183 1O0S NAI 0.005388 0.40113 3.26633
184 1N6B DMZ 0.01475 0.40067 3.26633
185 2BLE 5GP 0.004057 0.44065 3.26975
186 1N1G BCP 0.0008088 0.44863 3.27869
187 4QN7 G39 0.00471 0.41831 3.33333
188 1QB7 ADE 0.0005649 0.41099 3.38983
189 1I52 CTP 0.005248 0.41034 3.38983
190 3QP6 HL6 0.0004345 0.4267 3.39623
191 4OJ8 AKG 0.0004626 0.43514 3.41297
192 4OJ8 2TQ 0.0007122 0.43224 3.41297
193 1M5B BN1 0.02121 0.40878 3.42205
194 3WSJ MK1 0.002653 0.44043 3.44828
195 1U5R ATP 0.0008868 0.41811 3.44828
196 2X61 NGA GAL SIA 0.01685 0.41303 3.48837
197 3ZRR PXG 0.0003798 0.43829 3.51759
198 1QPB TPP 0.002115 0.42126 3.51759
199 2GSD NAD 0.004421 0.4194 3.51759
200 1EB9 HBA 0.001071 0.40886 3.51759
201 1QPB PYM 0.00498 0.40706 3.51759
202 2QS8 MET 0.007544 0.40015 3.51759
203 4DVE BTN 0.0001731 0.4299 3.53535
204 1NUS APC 0.008216 0.41387 3.57143
205 1NUS NMN 0.01359 0.40859 3.57143
206 3GWT 066 0.009625 0.40135 3.68272
207 1PR9 NAP 0.002752 0.42514 3.68852
208 3D3W NAP 0.007367 0.40589 3.68852
209 1Q6O LG6 0.002629 0.40115 3.7037
210 2PT9 S4M 0.004253 0.40817 3.73832
211 2R40 EPH 0.0004911 0.45096 3.7594
212 3OIG IMJ 0.009185 0.40453 3.7594
213 2YBQ UP2 0.002364 0.43135 3.76712
214 2YBQ SAH 0.002236 0.40998 3.76712
215 2C7G ODP 0.005645 0.43166 3.76884
216 2C7G FAD 0.006313 0.43036 3.76884
217 4G87 UD1 0.00448 0.42972 3.76884
218 1P1M MET 0.002015 0.4154 3.76884
219 1ZFJ IMP 0.03679 0.41479 3.76884
220 2C9O ADP 0.02727 0.41015 3.76884
221 1G41 ADP 0.02216 0.40662 3.76884
222 3S7O LBV 0.002461 0.42445 3.79009
223 1MZV AMP 0.0007638 0.40547 3.82979
224 2AE2 NAP 0.007192 0.41621 3.84615
225 2AE2 PTO 0.007192 0.41621 3.84615
226 2PTR 2SA 0.0006697 0.44032 3.8961
227 1I0Z NAI 0.0009949 0.43834 3.9039
228 1NNU NAD 0.009413 0.43577 3.93013
229 1NNU TCT 0.009413 0.43577 3.93013
230 4C0X FMN 0.006308 0.40313 3.94089
231 1B8U OAA 0.008634 0.40441 3.95137
232 3R35 4CO 0.0009566 0.44043 3.97351
233 1RM0 D6P 0.001805 0.44823 4.0201
234 1RM0 NAI 0.001568 0.44798 4.0201
235 3QO8 SSA 0.00155 0.4094 4.0201
236 3IL6 B83 0.000593 0.43117 4.04984
237 3VGL BGC 0.003204 0.41728 4.04984
238 2YHW BM3 0.006667 0.4063 4.08163
239 4HA6 FAD 0.003826 0.43024 4.13386
240 1L3I SAH 0.0009971 0.43372 4.16667
241 2D0V PQQ 0.002955 0.40552 4.16667
242 1JCM 137 0.001455 0.43049 4.2471
243 4R33 SAH 0.0004449 0.45622 4.27136
244 4R33 TRP 0.0004449 0.45622 4.27136
245 3F3E LEU 0.000711 0.45332 4.27136
246 3M6W SAM 0.0005442 0.42573 4.27136
247 4KWI NAP 0.004388 0.42489 4.27136
248 4KWI 1TJ 0.004643 0.42489 4.27136
249 2QA1 FAD 0.005898 0.41443 4.27136
250 3NKS FAD 0.007059 0.4135 4.27136
251 1K6M AGS 0.004592 0.40206 4.27136
252 4UAL 3FV 0.003115 0.40067 4.27136
253 2Q28 ADP 0.004066 0.40042 4.27136
254 1LSS NAD 0.004128 0.40202 4.28571
255 1L1Q 9DA 0.00216 0.41053 4.30108
256 1LTH NAD 0.01633 0.41494 4.38871
257 1UDB UFG 0.00419 0.43474 4.43787
258 1UDB NAD 0.00419 0.43474 4.43787
259 3BLI ACO 0.001646 0.41867 4.45104
260 1VDC FAD 0.00541 0.42764 4.5045
261 3WE0 FAD 0.003623 0.4312 4.52261
262 3S2Y FMN 0.003376 0.40144 4.52261
263 4DEM YS4 0.02106 0.42031 4.53333
264 1YB5 NAP 0.003038 0.42467 4.5584
265 3CKJ CIT 0.003516 0.41283 4.55927
266 1ECM TSA 0.0005825 0.40891 4.58716
267 3WBF NAP 0.004637 0.41108 4.59016
268 3WBF API 0.00884 0.40519 4.59016
269 2NLI FMN 0.01913 0.40643 4.61957
270 2NLI LAC 0.01913 0.40643 4.61957
271 1WVC CTP 0.00285 0.4597 4.6332
272 3PVT 3HC 0.002239 0.43343 4.6332
273 1F3L SAH 0.002341 0.41297 4.6729
274 4Q3S X7A 0.006117 0.40435 4.67532
275 3B1J NAD 0.003456 0.41738 4.71976
276 3PNL ADP 0.001207 0.42369 4.73934
277 3L0E G58 0.0008482 0.43641 4.74308
278 1ME8 RVP 0.005265 0.44579 4.77387
279 1M7Y PPG 0.004599 0.41257 4.77387
280 3DNT ATP 0.002904 0.41121 4.77387
281 4IVG ANP 0.002983 0.41077 4.77387
282 2NXW TPP 0.006852 0.40835 4.77387
283 3ZLM ANP 0.001673 0.41258 4.78723
284 1LL2 UPG 0.0006621 0.43146 4.8048
285 2WUF KEM 0.004691 0.40339 4.811
286 4DL8 UMP AF3 PO4 0.00157 0.41563 4.82759
287 3ZEI AWH 0.005778 0.40739 4.83871
288 1OFH ADP 0.004865 0.40595 4.83871
289 2CJE DUN 0.0004799 0.40092 4.85075
290 1U7Z PMT 0.001709 0.43326 4.86726
291 3FXU TSU 0.002152 0.41778 4.91803
292 1D3V ABH 0.006486 0.4012 4.95356
293 1RSD PSB 0.04268 0.42834 4.95868
294 2AEB ABH 0.006577 0.40097 4.96894
295 4R38 RBF 0.01226 0.40162 5
296 1KY8 NAP 0.02221 0.42301 5.02513
297 2AMV BIN 0.02656 0.40045 5.02513
298 4M5P FMN 0.004627 0.40018 5.02513
299 3H22 B53 0.00164 0.40615 5.05051
300 1L2T ATP 0.005736 0.40011 5.10638
301 1TB4 PEJ 0.002933 0.42014 5.12129
302 4L1F FAD 0.005287 0.41517 5.22193
303 4L1F COS 0.004512 0.40402 5.22193
304 4AF0 IMP 0.003764 0.43415 5.27638
305 2HGS ADP 0.0006702 0.43322 5.27638
306 4RJK TPP 0.001788 0.42557 5.27638
307 2VJJ RAM GLC GAL NAG NAG GLC 0.01017 0.41749 5.27638
308 4RJK TDL 0.003769 0.41592 5.27638
309 3RO7 TDR 0.003091 0.41645 5.28302
310 1R18 SAH 0.002893 0.40955 5.28634
311 4NTD FAD 0.008561 0.41117 5.29412
312 2V7T SAH 0.02424 0.42041 5.35117
313 4QN6 LNV 0.004056 0.42312 5.37084
314 2BKA NDP 0.003033 0.4182 5.3719
315 1P72 ADP 0.006517 0.40797 5.38922
316 1P72 THM 0.0004631 0.40293 5.38922
317 1OAA OAA 0.0005745 0.46381 5.40541
318 1G6O ADP 0.01887 0.40957 5.45455
319 3W54 RNB 0.0001477 0.44338 5.47112
320 2FR6 CTN 0.002027 0.40954 5.47945
321 2FR6 URI 0.002264 0.40778 5.47945
322 3H9E NAD 0.005737 0.40471 5.49133
323 3V91 UPG 0.003295 0.43654 5.49828
324 3CQD ATP 0.002298 0.43299 5.50162
325 4DEC 3PG 0.004719 0.40795 5.52326
326 4DEC UDP 0.004719 0.40795 5.52326
327 1Y13 BIO 0.0005332 0.41384 5.52486
328 3T31 FAD 0.003469 0.44055 5.52764
329 1E8G FAD 0.01458 0.43211 5.52764
330 1E8G FCR 0.02125 0.42387 5.52764
331 1KBJ FMN 0.001753 0.42279 5.52764
332 1KBI FMN 0.00295 0.41574 5.52764
333 1KBI PYR 0.00295 0.41574 5.52764
334 3T31 DCQ 0.02354 0.40685 5.52764
335 1GRO ICT 0.02025 0.40308 5.52764
336 2Y6P CTP 0.0001778 0.4302 5.55556
337 2P41 G1G 0.0006073 0.4039 5.57377
338 4KQI RBZ 0.00332 0.41939 5.61798
339 4KQI NIO 0.00332 0.41939 5.61798
340 1VF1 GSH 0.0006994 0.42641 5.67686
341 4WX0 HXD 0.001946 0.40585 5.70342
342 3MBG FAD 0.001358 0.427 5.7554
343 1Q3Q ANP 0.00105 0.46396 5.77889
344 2IXB A2G 0.0008048 0.45236 5.77889
345 2IXB NAD 0.001834 0.42943 5.77889
346 1K97 ASP 0.02891 0.41419 5.77889
347 1K97 CIR 0.02891 0.41419 5.77889
348 4AQL TXC 0.002211 0.40607 5.77889
349 2NVK FAD 0.0174 0.40156 5.77889
350 4M37 SAH 0.002955 0.40552 5.8309
351 4NM5 ADP 0.001709 0.41807 5.83554
352 3E8N ATP 0.005999 0.42133 5.8651
353 3E8N VRA 0.005999 0.42133 5.8651
354 1UWZ THU 0.001501 0.40991 5.88235
355 3FC2 IBI 0.000173 0.46776 5.97015
356 4PLG OXM 0.001301 0.44285 5.98802
357 4PLG NAI 0.001301 0.44285 5.98802
358 1XOC VAL ASP SER LYS ASN THR SER SER TRP 0.008121 0.41408 6.03015
359 2PUL ACP 0.0001336 0.44763 6.04534
360 4COQ SAN 0.008488 0.40868 6.07287
361 2R42 FPS 0.001253 0.41923 6.07595
362 3A2Q ACA ACA 0.0004648 0.4306 6.08519
363 1XIU REA 0.002988 0.40132 6.08696
364 1SAY PYR 0.02417 0.4296 6.09418
365 4TMK T5A 0.0084 0.44843 6.10329
366 2J07 FAD 0.006228 0.42594 6.19048
367 2J07 HDF 0.006228 0.42594 6.19048
368 1DAK ADP 0.01767 0.40037 6.25
369 1DAK DPU 0.01767 0.40037 6.25
370 1QW9 KHP 0.002313 0.41822 6.28141
371 2YGO PCF 0.0008293 0.43991 6.38298
372 3O55 FAD 0.003561 0.4111 6.4
373 2QLX RM4 0.001087 0.45503 6.48148
374 4GYW UDP 0.003718 0.41875 6.53266
375 2E2R 2OH 0.0003907 0.45981 6.55738
376 4JK3 NAD 0.00552 0.40815 6.56371
377 1NVV GNP 0.004045 0.409 6.62651
378 4OB6 S2T 0.0005773 0.42481 6.74487
379 1EP2 ORO 0.001096 0.44214 6.75241
380 1EP2 FMN 0.001706 0.42635 6.75241
381 1EP2 FAD 0.001679 0.42014 6.75241
382 3LPF Z77 0.001909 0.42296 6.78392
383 1X54 4AD 0.002245 0.41709 6.78392
384 3ZOD HQE 0.002436 0.41892 6.80628
385 3ZOD FMN 0.002436 0.41892 6.80628
386 1T0I FMN 0.00128 0.41683 6.80628
387 1F5F DHT 0.002349 0.40511 6.82927
388 2VEZ G6P 0.004915 0.41144 6.84211
389 4INB 1F6 0.0008245 0.42591 6.84932
390 2HMT NAI 0.02034 0.40378 6.94444
391 3CIP ATP 0.002641 0.43583 7.03125
392 1C0I BE2 0.003029 0.43625 7.16253
393 1C0I FAD 0.003029 0.43625 7.16253
394 1SS4 GSH 0.009989 0.44028 7.18954
395 1GSA ADP 0.003728 0.43432 7.27848
396 1GSA GSH 0.005557 0.42173 7.27848
397 1TDF FAD 0.01991 0.40338 7.27848
398 1TDF NAP 0.04116 0.40338 7.27848
399 3Q9T FAY 0.0005985 0.45751 7.28643
400 1E2S CSN 0.0023 0.40093 7.28643
401 1C1L GAL BGC 0.001311 0.45136 7.29927
402 1UNB AKG 0.002306 0.43872 7.3955
403 1UNB PN1 0.01189 0.41225 7.3955
404 1R6D DAU 0.01306 0.41487 7.4184
405 1R6D NAD 0.01462 0.41354 7.4184
406 1V1A KDG 0.002403 0.40979 7.44337
407 2Q2V NAD 0.004927 0.4127 7.45098
408 3KMZ EQO 0.002652 0.41751 7.5188
409 2EWM NAD 0.0009967 0.43974 7.63052
410 3F81 STT 0.01682 0.4139 7.65027
411 2UZ2 BTN 0.0006482 0.423 7.69231
412 1A8R GTP 0.00385 0.4013 7.69231
413 2WQP WQP 0.015 0.40675 7.73639
414 2C31 ADP 0.008376 0.43359 7.78894
415 4OYA 1VE 0.02226 0.42553 7.78894
416 3BL6 FMC 0.001019 0.42043 7.82609
417 9LDB NAD 0.009979 0.40074 7.83133
418 1RYI FAD 0.002101 0.43885 7.8534
419 1RYI GOA 0.01211 0.40977 7.8534
420 1XVA SAM 0.001368 0.41783 7.87671
421 1KDK DHT 0.0002249 0.45089 7.9096
422 1DR1 NAP 0.007872 0.4116 7.93651
423 1DR1 HBI 0.007872 0.4116 7.93651
424 4IAE 1DX 0.02215 0.40339 7.93651
425 2R14 TXD 0.005101 0.41212 7.95756
426 1ZK4 AC0 0.01946 0.42083 7.96813
427 1ZK4 NAP 0.01946 0.42083 7.96813
428 1CKM GTP 0.001084 0.42154 8.18182
429 1CSI CMX 0.01434 0.40312 8.29146
430 1CSI OAA 0.01434 0.40312 8.29146
431 4C12 ADP 0.02632 0.40206 8.29146
432 1HYE NAP 0.004051 0.40578 8.30671
433 2GJ3 FAD 0.003105 0.40473 8.33333
434 2J5S KTA 0.002205 0.4082 8.36502
435 3BW2 FMN 0.002425 0.42334 8.40108
436 4BMO FMN 0.0008807 0.43414 8.40336
437 1Y75 NAG 0.0005086 0.40747 8.47458
438 4FR3 0V4 0.005483 0.44098 8.54701
439 4FR3 LYS ARG ARG LYS SEP VAL 0.009945 0.42977 8.54701
440 1C3V NDP 0.002502 0.42417 8.57143
441 1FIQ FAD 0.003177 0.4239 8.6758
442 1FIQ SAL 0.003098 0.42186 8.6758
443 3QP4 HL0 0.00166 0.40833 8.79121
444 2R7K ACP 0.02161 0.42485 8.86427
445 2R7K AMZ 0.02161 0.42485 8.86427
446 2OWZ F6P 0.01548 0.40177 9.03614
447 2RHW C0E 0.007487 0.43071 9.18728
448 1IIM TTP 0.0005189 0.45878 9.24658
449 1JQI CAA 0.0001665 0.45971 9.27835
450 2V6O FAD 0.002724 0.45597 9.29648
451 1LVL FAD 0.002282 0.43939 9.54774
452 2F59 INI 0.00237 0.40706 9.55414
453 2Y7G AAE 0.002345 0.40294 9.57447
454 2PWY SAH 0.005247 0.40156 9.68992
455 1D6H COA 0.0009732 0.45448 9.81912
456 3T2W BTN 0.0004792 0.41283 9.83607
457 2NX1 PEP 0.001092 0.43378 10.1124
458 1T57 FMN 0.000719 0.43208 10.1942
459 3C1O NAP 0.003555 0.40955 10.2804
460 1QY1 PRZ 0.0006628 0.43144 10.3448
461 4P3H 25G 0.02133 0.40052 10.3627
462 3TN7 NJP 0.009889 0.40089 10.8949
463 1GR0 NAD 0.002823 0.4553 10.8992
464 3IIS PID 0.01642 0.42031 11.2583
465 1I7L ATP 0.0005257 0.43905 11.3269
466 2ZSC BTN 0.001761 0.40505 11.3475
467 1H2B NAJ 0.006079 0.4116 11.4206
468 3HF3 FMN 0.004529 0.40228 11.4613
469 1EXB NDP 0.03646 0.4057 11.6505
470 1UXG NAD 0.0155 0.40079 11.6505
471 1UXG FUM 0.0155 0.40079 11.6505
472 1RHC F42 ACN 0.004595 0.41258 12.4242
473 4O1M NAD 0.004043 0.41474 12.6984
474 4BCS BTN 0.001387 0.41114 12.8
475 1N9L FMN 0.0005297 0.4011 12.844
476 2YNM PMR 0.000806 0.43388 13.0653
477 1Y52 BTN 0.01471 0.40453 13.4921
478 1JYQ MAZ PTR PTM ASN 0.003676 0.42372 13.5417
479 1BGQ RDC 0.001668 0.4252 13.7778
480 1I2B NAD 0.02135 0.4073 13.8614
481 1I2B USQ 0.02135 0.4073 13.8614
482 1I2B UPG 0.02135 0.4073 13.8614
483 3SFI 3SF 0.013 0.4058 13.9831
484 1TOI HCI 0.007354 0.40334 14.1414
485 1MQ0 BRD 0.001638 0.40618 14.2857
486 3GE7 AFQ 0.005094 0.41462 14.7668
487 1WUR 8DG 0.0006066 0.43483 15
488 4Q0P 0MK 0.035 0.41495 15
489 3D2M COA 0.03988 0.41399 15.8291
490 1BDB NAD 0.02743 0.41114 15.8845
491 2QDT I38 0.001745 0.40755 18.2156
492 4IEN GDP 0.007455 0.40311 18.4049
493 3ZZS TRP 0.003861 0.42173 18.4615
494 2YJ0 420 0.01062 0.42083 20.2899
495 4NAT ADP 0.04114 0.40735 21.25
496 4NAT 2W5 0.01461 0.40083 21.25
497 2YC5 6BC 0.0005012 0.45686 21.4912
498 2RH4 EMO 0.001054 0.45506 23.1047
499 2P8B NSK 0.00008807 0.4386 29.5393
500 3DG6 MUC 0.0002552 0.46966 30.5177
501 3DER ALA LYS 0.00004856 0.47345 32.1739
502 2GGH NLQ 0.001014 0.44269 32.8
503 3UXL CFI 0.000002776 0.60717 34.2037
504 4CCO OGA 0.00006777 0.428 35
505 1TKK ALA GLU 0.0003347 0.46938 35.5191
506 4GQB 0XU 0.02001 0.40708 36.3636
507 3CXO 3LR 0.0000009337 0.54375 36.6834
508 3CXO 1N5 0.000002103 0.54092 36.6834
509 2QJN KDG 0.0001039 0.48722 37.6884
510 3DGB MUC 0.0001467 0.48638 37.6963
511 1EC9 XYH 0.0001103 0.46986 38.4422
512 2DW7 SRT 0.00000002148 0.61 42.4165
Pocket No.: 2; Query (leader) PDB : 2PP3; Ligand: LGT; Similar sites found: 96
This union binding pocket(no: 2) in the query (biounit: 2pp3.bio3) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2E1A MSE 0.005819 0.41835 None
2 1OTH PAO 0.00005183 0.43989 1.55763
3 3TO7 COA 0.001605 0.40218 1.81159
4 1YTM OXD 0.02292 0.40834 2.01005
5 2F2U M77 0.01067 0.40299 2.01005
6 1FS5 TLA 0.0003188 0.40906 2.25564
7 2RL1 UD1 0.0007484 0.40302 2.26131
8 4EA7 COA 0.004792 0.40606 2.27273
9 4EA7 JB2 0.004792 0.40606 2.27273
10 3SHR CMP 0.007146 0.41007 2.34114
11 4A8T PAO 0.0003515 0.44324 2.35988
12 2R85 AMP 0.002979 0.40123 2.39521
13 1V5F FAD 0.02564 0.40712 2.51256
14 1V5F TPP 0.02564 0.40712 2.51256
15 1HV9 COA 0.003473 0.40041 2.51256
16 4CS4 AXZ 0.002115 0.40364 2.55474
17 1H6W SER LEU ASN TYR ILE ILE LYS VAL LYS GLU 0.0001952 0.44239 2.5641
18 4HZX G39 0.00007609 0.44475 2.57732
19 3M0J OAF 0.0008545 0.40174 2.60586
20 1LGT BP3 0.004812 0.4291 2.6936
21 4KCF FMN 0.001238 0.40454 2.76382
22 1Z44 FMN 0.007009 0.40209 2.95858
23 4B63 ORN 0.0003805 0.47332 3.01508
24 4B63 FAD 0.0003805 0.47332 3.01508
25 4B63 NAP 0.0003998 0.47332 3.01508
26 2NCD ADP 0.004814 0.43236 3.01508
27 2IMP NAI 0.003267 0.41946 3.01508
28 1FWY UD1 0.0001311 0.42772 3.02115
29 4KS1 2H8 0.001944 0.40481 3.07692
30 4E28 0MZ 0.02402 0.40109 3.07692
31 1EJE FMN 0.002564 0.40663 3.125
32 3DX5 DHB 0.01437 0.4004 3.14685
33 1G7V PAI 0.001364 0.40551 3.16901
34 2C1Q BTN 0.000479 0.41974 3.1746
35 3UC5 ATP 0.005065 0.40213 3.18471
36 2BGM NAJ 0.003613 0.4063 3.23741
37 3O9P MHI 0.002736 0.41532 3.26633
38 4B7J G39 0.0007584 0.40607 3.26633
39 2Q8C AKG 0.01465 0.40968 3.40909
40 1OMZ UD2 0.0005145 0.42321 3.41297
41 4HE2 AMP 0.0006796 0.40473 3.5503
42 1I9G SAM 0.0005494 0.42436 3.57143
43 1VQ2 DDN 0.0009389 0.42888 3.62694
44 3EAU NDP 0.001625 0.43004 3.66972
45 3EAU PDN 0.001625 0.43004 3.66972
46 4GLJ RHB 0.0002675 0.41837 3.7037
47 1JH7 UVC 0.001684 0.40153 3.7037
48 3OIG NAD 0.001272 0.42294 3.7594
49 2WLT ASP 0.0003247 0.41128 3.91566
50 3MMR ABH 0.004507 0.4016 4.0201
51 2BNF UTP 0.001595 0.40227 4.14938
52 3FS8 ACO 0.006055 0.41223 4.3956
53 3C2O NTM 0.01104 0.40591 4.42177
54 4Q3R XA2 0.00009133 0.42091 4.67532
55 2ZO9 MLI 0.00005052 0.49381 4.74453
56 4KQL 1SG 0.005241 0.40373 5.02513
57 1JA9 NDP 0.0003279 0.4488 5.10949
58 3CKZ ZMR 0.0001871 0.43492 5.19481
59 2XBP ATP 0.001435 0.41145 5.30973
60 1D7O TCL 0.001428 0.43317 5.38721
61 1D7O NAD 0.001428 0.43317 5.38721
62 1F8F NAD 0.0006974 0.42839 5.39084
63 1PEA ACM 0.02895 0.41281 5.45455
64 3MB5 SAM 0.0006828 0.42516 5.4902
65 2A0W DIH 0.0003667 0.41635 5.53633
66 3K37 BCZ 0.003557 0.41702 5.54156
67 1G8S MET 0.01748 0.41234 5.65217
68 1O7N IND 0.000004528 0.44674 6.03015
69 3H86 AP5 0.000462 0.42729 6.25
70 3K9W ADE 0.002667 0.42942 6.41711
71 3K9W 4PS 0.002667 0.42942 6.41711
72 2PJL 047 0.001063 0.40227 6.47773
73 3S9K CIT 0.03582 0.42333 6.77966
74 2QXX TTP 0.000904 0.40818 6.84211
75 4JP3 CIT 0.0005645 0.40996 7.11297
76 4GZP G39 0.000616 0.41632 7.12468
77 1SS4 CIT 0.003794 0.4875 7.18954
78 1F7L COA 0.0004227 0.41447 7.43802
79 1V1A ADP 0.0007366 0.40073 7.44337
80 1YBH FAD 0.002425 0.42731 7.78894
81 4F4S EFO 0.01431 0.40641 7.89474
82 1RBL CAP 0.006989 0.41261 8.25688
83 2P2V CSF 0.003605 0.4016 8.33333
84 4NVP 7CH 0.001139 0.40326 9.09091
85 3L02 SN0 0.0006209 0.40733 9.47075
86 3L02 CP 0.0006209 0.40733 9.47075
87 1DMR PGD 0.04463 0.41078 9.54774
88 3QVL 5HY 0.001336 0.40795 9.79592
89 1AL8 FMN 0.00006831 0.45775 11.1421
90 4A3R CIT 0.0006366 0.41101 11.3065
91 2P1O IHP 0.0005205 0.40673 14.375
92 2P1O NLA 0.0005205 0.40673 14.375
93 1RP0 AHZ 0.001179 0.42981 14.4366
94 4IZC 1GZ 0.002519 0.40625 14.9091
95 3NBK PNS 0.0005392 0.40702 16.3842
96 4IEN COA 0.00029 0.41945 18.4049
Pocket No.: 3; Query (leader) PDB : 2PP3; Ligand: LGT; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 2pp3.bio3) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 2PP3; Ligand: LGT; Similar sites found: 22
This union binding pocket(no: 4) in the query (biounit: 2pp3.bio5) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1W31 SHO 0.000000003899 0.50853 1.75439
2 1FRW GTP 0.00000002215 0.42728 2.06186
3 3HB5 E2B 0.006954 0.41339 2.44648
4 1JQ5 NAD 0.00000002832 0.46317 2.7027
5 3OYZ ACO 0.001753 0.40511 3.01508
6 3GX0 GDS 0.01638 0.41035 3.25581
7 1DXY NAD 0.000001481 0.41238 3.3033
8 3Q2I HP7 0.000001024 0.4021 3.38983
9 1JQN DCO 0.0005169 0.42977 3.51759
10 3TI8 LNV 0.00008197 0.43722 3.5443
11 1ONX ASP 0.0001193 0.47005 3.58974
12 2PR5 FMN 0.00539 0.433 6.06061
13 1BGV GLU 0.00005524 0.44486 6.78392
14 3PHQ KDO 0.00194 0.55085 7.8341
15 1MXI SAH 0.008579 0.42478 8.125
16 1TV5 A26 0.005891 0.4218 10.158
17 1TV5 ORO 0.01405 0.42083 10.158
18 1TV5 FMN 0.0005801 0.40885 10.158
19 2PN6 GLN 0.0000003097 0.41313 11.3333
20 3KPE TM3 0.0114 0.45698 11.7647
21 1CFV E3G 0.01179 0.4025 17.6991
22 1GXU 2HP 0.0001199 0.48614 27.4725
Pocket No.: 5; Query (leader) PDB : 2PP3; Ligand: LGT; Similar sites found: 2
This union binding pocket(no: 5) in the query (biounit: 2pp3.bio1) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2YNE NHW 0.04888 0.41326 2.08333
2 2YNE YNE 0.04888 0.41326 2.08333
Pocket No.: 6; Query (leader) PDB : 2PP3; Ligand: LGT; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 2pp3.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 2PP3; Ligand: LGT; Similar sites found: 27
This union binding pocket(no: 7) in the query (biounit: 2pp3.bio6) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4HPP GLU 0.00008071 0.40629 1.50754
2 4TSK NDP 0.000856 0.40169 2
3 4PNI KQQ 0.002931 0.40008 2.01005
4 2R0N FAD 0.001011 0.41342 2.03046
5 4MWV BCZ 0.00005769 0.41391 2.06186
6 2FH5 GTP 0.0001345 0.41189 2.16216
7 1EDO NAP 0.0005675 0.41426 2.45902
8 2BJF DXC 0.00001927 0.43151 2.73556
9 1A5Z NAD 0.0002002 0.41161 2.82132
10 2XD9 XD9 0.0009991 0.43335 2.99401
11 3O03 NAP 0.0001183 0.42549 3.09278
12 1RLZ NAD 0.00003195 0.44837 3.25203
13 3DJL FAD 0.0009542 0.41295 3.26633
14 2X61 CH 0.00002673 0.42518 3.48837
15 1YBQ BDH 0.00004374 0.41341 3.58974
16 1YOE RIB 0.000001667 0.4342 3.72671
17 4EKV BTN 0.00007345 0.40283 3.77358
18 2GJN FMN 0.002055 0.4021 3.96341
19 3PLN U5P 0.01535 0.41606 4.0201
20 1NVU GTP 0.00002883 0.44049 4.21687
21 2FWP ICR 0.00005821 0.41022 4.37158
22 3AIQ HBO 0.00005153 0.42401 5.27638
23 2Q1A 2KT 0.00000799 0.40042 5.80205
24 1WKL ATP 0.0006759 0.40024 7.29927
25 2RHQ GAX 0.003306 0.40453 7.82313
26 2WL9 MBD 0.0000111 0.40254 7.86885
27 2ET1 GLV 0.0001121 0.40788 7.9602
Pocket No.: 8; Query (leader) PDB : 2PP3; Ligand: LGT; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 2pp3.bio6) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 9; Query (leader) PDB : 2PP3; Ligand: LGT; Similar sites found: 9
This union binding pocket(no: 9) in the query (biounit: 2pp3.bio4) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4DA6 GA2 0.00000922 0.40968 3.16206
2 1XP8 AGS 0.000001732 0.41401 3.27869
3 5AYC BGC BMA 0.004971 0.40837 3.88601
4 3A2Y TS5 0.01925 0.40266 4.06091
5 1XMV ADP 0.00001165 0.40404 4.49438
6 1WKL ADP 0.0000007955 0.41706 7.29927
7 2JEN GLC GLC BGC XYS BGC XYS 0.00005028 0.40731 8.04598
8 1TV5 N8E 0.0006195 0.4579 10.158
9 1QCA FUA 0.00000981 0.41783 12.2066
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