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Receptor
PDB id Resolution Class Description Source Keywords
2P7G 2.1 Å NON-ENZYME: TRANSCRIPT_TRANSLATE X-RAY STRUCTURE OF ESTROGEN RELATED RECEPTOR G IN COMPLEX WITH BISPHENOL A. HOMO SAPIENS THREE LAYERED ALPHA HELICAL SANDWICH HORMONE RECEPTOR
Ref.: STRUCTURAL DETERMINATION OF ESTROGEN-RELATED RECEPTOR GAMMA IN THE PRESENCE OF PHENOL DERIVATIVE COMPOUNDS. J.STEROID BIOCHEM.MOL.BIOL. V. 108 44 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
2OH A:1;
Valid;
none;
Kd = 0.297 uM
228.286 C15 H16 O2 CC(C)...
NA A:500;
Part of Protein;
none;
submit data
22.99 Na [Na+]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2E2R 1.6 Å NON-ENZYME: TRANSCRIPT_TRANSLATE CRYSTAL STRUCTURE OF HUMAN ESTROGEN-RELATED RECEPTOR GAMMA L BINDING DOMAIN COMPLEX WITH BISPHENOL A HOMO SAPIENS ERR GAMMA BPA NUCLEAR RECEPTOR TRANSCRIPTION
Ref.: STRUCTURAL EVIDENCE FOR ENDOCRINE DISRUPTOR BISPHEN BINDING TO HUMAN NUCLEAR RECEPTOR ERR{GAMMA} J.BIOCHEM.(TOKYO) V. 142 517 2007
Members (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 291 families.
1 2ZAS ic50 = 13.9 nM 1OH C15 H16 O CC(C)(c1cc....
2 2EWP ic50 = 0.079 uM TXF C27 H31 N O3 CN(C)CCOc1....
3 1S9P - DES C18 H20 O2 CC/C(=C(/C....
4 2E2R Kd = 5.5 nM 2OH C15 H16 O2 CC(C)(c1cc....
5 2P7Z Kd = 0.262 uM OHT C26 H29 N O2 CC/C(=C(c1....
6 2GPU - OHT C26 H29 N O2 CC/C(=C(c1....
7 2P7A Kd = 0.788 uM 43M C7 H7 Cl O Cc1cc(ccc1....
8 2P7G Kd = 0.297 uM 2OH C15 H16 O2 CC(C)(c1cc....
9 1S9Q - OHT C26 H29 N O2 CC/C(=C(c1....
70% Homology Family (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 247 families.
1 2PJL ic50 = 190 nM 047 C23 H28 N2 Cc1ccc(cc1....
2 2ZAS ic50 = 13.9 nM 1OH C15 H16 O CC(C)(c1cc....
3 2EWP ic50 = 0.079 uM TXF C27 H31 N O3 CN(C)CCOc1....
4 1S9P - DES C18 H20 O2 CC/C(=C(/C....
5 2E2R Kd = 5.5 nM 2OH C15 H16 O2 CC(C)(c1cc....
6 2P7Z Kd = 0.262 uM OHT C26 H29 N O2 CC/C(=C(c1....
7 2GPU - OHT C26 H29 N O2 CC/C(=C(c1....
8 2P7A Kd = 0.788 uM 43M C7 H7 Cl O Cc1cc(ccc1....
9 2P7G Kd = 0.297 uM 2OH C15 H16 O2 CC(C)(c1cc....
10 1S9Q - OHT C26 H29 N O2 CC/C(=C(c1....
50% Homology Family (85)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 3ERT - OHT C26 H29 N O2 CC/C(=C(c1....
2 1YIM ic50 = 1.5 nM CM4 C28 H31 N O4 C[C@@H]1c2....
3 5W9C - OHT C26 H29 N O2 CC/C(=C(c1....
4 1XP6 ic50 = 0.4 nM AIU C28 H31 N O4 S C[C@@H]1CN....
5 5FQT ic50 = 160 nM 7QN C23 H27 N O3 Cc1c(ccc2c....
6 4IW6 - 1GU C18 H15 F3 N2 O2 C=CCCn1c(c....
7 5FQV ic50 = 610 nM VQI C23 H27 N O3 Cc1cc2c(cc....
8 4IW8 - KN3 C19 H17 F3 N2 O2 CC(=CCn1c2....
9 5FQR ic50 = 26 nM QHG C22 H25 N O3 CC(C)CN1CC....
10 2IOG ic50 = 8 nM IOG C33 H39 N3 O3 C[C@H](CCc....
11 1GWQ Kd = 76 nM LYS ILE LEU HIS ARG LEU LEU GLN ASP n/a n/a
12 4IVW - 1GJ C21 H15 F3 N2 O2 c1ccc(cc1)....
13 5U2B - 6WV C24 H29 N O C[C@]12CC[....
14 4IUI - 1GQ C18 H17 F3 N2 O2 CCCCn1c2c(....
15 1XQC ic50 = 63 nM AEJ C29 H33 N3 O c1ccc(cc1)....
16 1UOM ic50 = 19 nM PTI C28 H32 N2 O2 c1ccc(cc1)....
17 1XP1 ic50 = 0.5 nM AIH C28 H31 N O4 S C[C@H]1CN(....
18 2QXS - RAL C28 H27 N O4 S c1cc(ccc1c....
19 6CHZ - F3D C31 H36 N4 O2 CC/C(=C(/c....
20 2Q70 Ki = 8.3 nM DC8 C18 H16 F2 O3 c1cc(ccc1[....
21 2R6W Ki = 0.44 nM LLB C29 H29 N O4 S CC1CCN(CC1....
22 2QE4 Ki = 0.28 nM JJ3 C20 H22 O4 COCc1cc(cc....
23 5AK2 ic50 = 0.0039 uM 85Z C26 H19 F O5 Cc1cc(ccc1....
24 1XP9 ic50 = 1.3 nM AIJ C27 H29 N O4 S C[C@@H](CO....
25 4IV4 - 1GS C18 H17 F3 N2 O2 CC(C)Cn1c(....
26 5UFW - 86V C29 H31 N O4 C[C@H]1CCN....
27 2IOK ic50 = 1 nM IOK C26 H26 N2 O2 C[C@H](CCc....
28 3OSA - KN3 C19 H17 F3 N2 O2 CC(=CCn1c2....
29 5TN9 - 7EC C31 H32 Br N O6 S c1cc(ccc1C....
30 3UUC - 0D1 C14 H10 Cl2 O2 c1cc(ccc1C....
31 1GWR Kd = 250 nM ASN ALA LEU LEU ARG TYR LEU LEU ASP n/a n/a
32 4PP6 - LYS ILE LEU HIS ARG LEU LEU GLN ASP n/a n/a
33 2OUZ - C3D C28 H31 N O2 c1ccc(cc1)....
34 3OS9 - KN1 C17 H13 F3 N2 O2 C=CCn1c2c(....
35 1XPC ic50 = 1.7 nM AIT C27 H29 N O4 S C[C@H](COc....
36 2R6Y Ki = 0.32 nM LLC C27 H25 N O4 S c1cc(ccc1c....
37 4IU7 - 1GM C16 H13 F3 N2 O2 CCn1c(c2cc....
38 2POG Ki = 0.29 nM WST C18 H18 O3 c1cc(c2c(c....
39 5TNB - 7EB C28 H28 Br N O6 S CN(C)CCOc1....
40 1SJ0 ic50 = 0.8 nM E4D C27 H29 N O4 S c1cc(ccc1[....
41 5T92 ic50 = 16 nM 77W C25 H22 F N O3 C[C@]1(c2c....
42 5W9D - 9XY C25 H27 N O2 CC/C(=C(c1....
43 3DT3 - 369 C23 H18 O4 Cc1cc2cc(c....
44 5AAU ic50 = 13.8 uM XBR C20 H19 Cl N2 O2 c1ccc2c(c1....
45 5UFX - 86Y C29 H31 N O4 C[C@@H]1CC....
46 4IV2 - 1GR C18 H17 F3 N2 O2 CC(C)Cn1c2....
47 4IWC - 1GV C18 H16 O2 S Cc1cc(ccc1....
48 5FQP ic50 = 19 nM GQD C23 H27 N O3 C[C@@H]1Cc....
49 1YIN ic50 = 1.4 nM CM3 C29 H32 F N O4 C[C@@H]1c2....
50 4IVY - 1GT C18 H15 F3 N2 O2 C=CCCn1c2c....
51 2AYR Ki = 0.52 nM L4G C30 H31 N O5 S CS(=O)(=O)....
52 4IWF - 15Q C13 H9 Cl F N O3 c1cc(c(cc1....
53 5FQS ic50 = 44 nM J0W C23 H27 N O3 CC(C)CN1CC....
54 1QKT Kd = 0.92 nM EST C18 H24 O2 C[C@]12CC[....
55 5ACC ic50 = 0.676 nM KE9 C25 H25 F3 N2 O2 C[C@@H]1Cc....
56 1G5Y - REA C20 H28 O2 CC1=C(C(CC....
57 3PCU - LX8 C21 H24 O5 CC(=O)OC(C....
58 5MKJ - 4CU C21 H22 O4 CCCOc1ccc(....
59 1FBY Kd = 1.5 nM REA C20 H28 O2 CC1=C(C(CC....
60 4N5G ic50 = 14.5 uM K09 C23 H23 F N4 CC1=C(c2cc....
61 1HG4 - LPP C35 H69 O8 P CCCCCCCCCC....
62 1G2N - EPH C39 H68 N O8 P CCCC=CCC=C....
63 2PJL ic50 = 190 nM 047 C23 H28 N2 Cc1ccc(cc1....
64 2JJ3 Kd = 0.281 uM JJ3 C20 H22 O4 COCc1cc(cc....
65 2Z4B Ki = 0.44 nM DC8 C18 H16 F2 O3 c1cc(ccc1[....
66 5TOA - EST C18 H24 O2 C[C@]12CC[....
67 1QKM - GEN C15 H10 O5 c1cc(ccc1C....
68 2GIU ic50 = 1.5 nM FBR C17 H19 Br O2 CCCC[C@@]1....
69 1QKN - RAL C28 H27 N O4 S c1cc(ccc1c....
70 1U9E ic50 = 5.7 nM 397 C14 H10 O3 c1cc(ccc1c....
71 1U3Q ic50 = 3.5 nM 272 C13 H9 N O4 c1cc2c(cc1....
72 2I0G Ki = 0.19 nM I0G C18 H18 O3 c1cc(ccc1[....
73 1HJ1 - PMB C6 H5 Hg O3 S c1cc(ccc1S....
74 2FSZ - OHT C26 H29 N O2 CC/C(=C(c1....
75 2NV7 ic50 = 5 nM 555 C17 H13 N O2 c1ccc2c(c1....
76 3FS1 - MYR C14 H28 O2 CCCCCCCCCC....
77 2ZAS ic50 = 13.9 nM 1OH C15 H16 O CC(C)(c1cc....
78 2EWP ic50 = 0.079 uM TXF C27 H31 N O3 CN(C)CCOc1....
79 1S9P - DES C18 H20 O2 CC/C(=C(/C....
80 2E2R Kd = 5.5 nM 2OH C15 H16 O2 CC(C)(c1cc....
81 2P7Z Kd = 0.262 uM OHT C26 H29 N O2 CC/C(=C(c1....
82 2GPU - OHT C26 H29 N O2 CC/C(=C(c1....
83 2P7A Kd = 0.788 uM 43M C7 H7 Cl O Cc1cc(ccc1....
84 2P7G Kd = 0.297 uM 2OH C15 H16 O2 CC(C)(c1cc....
85 1S9Q - OHT C26 H29 N O2 CC/C(=C(c1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 2OH; Similar ligands found: 5
No: Ligand ECFP6 Tc MDL keys Tc
1 2OH 1 1
2 1OH 0.724138 0.9
3 0CZ 0.466667 0.653846
4 27L 0.454545 0.666667
5 HQE 0.409091 0.65
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2E2R; Ligand: 2OH; Similar sites found with APoc: 396
This union binding pocket(no: 1) in the query (biounit: 2e2r.bio1) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 5NNT DPV None
2 1YC4 43P None
3 3KPE TM3 None
4 4LWU 20U None
5 2CB8 MYA None
6 3RET PYR None
7 3RET SAL None
8 3GWL FAD None
9 3B6C SDN None
10 2P7Q GG6 None
11 4F4S EFO None
12 4KJU 1RH None
13 3RV5 DXC None
14 3WQM B29 0.819672
15 4WQ2 3SU 1.15607
16 3AQT RCO 1.22951
17 1TMX HGX 1.22951
18 4MNS 2AX 1.25786
19 2HFN FMN 1.30719
20 2AK3 AMP 1.76991
21 4RYV ZEA 1.93548
22 3NB0 G6P 2.04918
23 3WXL ADP 2.04918
24 5B0I BOG 2.04918
25 5FUS DAO 2.04918
26 5FBK TCR 2.04918
27 4E8C GAL 2.04918
28 4DR9 BB2 2.08333
29 4RHP PEF 2.12766
30 1S17 GNR 2.22222
31 6EK3 OUL 2.26244
32 3W54 RNB 2.45902
33 5A1S FLC 2.45902
34 6F6E PLM 2.45902
35 2BP1 FLC 2.45902
36 4U0S ADP 2.45902
37 4E70 N7I 2.45902
38 2HFK E4H 2.45902
39 2Z7I 742 2.45902
40 3RMK BML 2.45902
41 5K52 OCD 2.45902
42 3KFF ZBT 2.46914
43 3KFF XBT 2.46914
44 3E3U NVC 2.53807
45 4CUB GAL NAG 2.73224
46 4G6I RS3 2.85714
47 4OB6 S2T 2.86885
48 3R9V DXC 2.86885
49 2O1V ADP 2.86885
50 6D28 NEC 2.86885
51 4DXJ 0M9 2.86885
52 4JZX 476 2.86885
53 5B4B LP5 2.86885
54 2D09 FLV 2.86885
55 5A8E XTK 2.86885
56 4HE2 AMP 2.86885
57 5F5N 5VD 2.86885
58 5U97 PIT 2.86885
59 4K10 NI9 2.86885
60 1JU4 BEZ 2.86885
61 2WTN FER 2.86885
62 2PX6 DH9 2.86885
63 6CIB ADP 2.86885
64 3WUR O4B 2.92398
65 1POC GEL 2.98507
66 2WOR 2AN 3
67 5C9J DAO 3.0303
68 5I8F ML1 3.0303
69 5WL1 CUY 3.0303
70 5WL1 D3D 3.0303
71 4URN NOV 3.11111
72 4R29 SAM 3.125
73 2YLD CMO 3.14961
74 3IX9 MTX 3.15789
75 2F2G HMH 3.16742
76 3OJI PYV 3.1746
77 6BR8 6OU 3.27869
78 2BIF BOG 3.27869
79 6BR9 PGV 3.27869
80 5KD8 TNR 3.27869
81 3G58 988 3.27869
82 5EE7 5MV 3.27869
83 1TZD ADP 3.27869
84 2HZL PYR 3.27869
85 6BR8 PGV 3.27869
86 1GNI OLA 3.27869
87 4MRP GSH 3.27869
88 2Q8G AZX 3.27869
89 3OTH CLJ 3.27869
90 5OM2 DXT 3.27869
91 3G4G D71 3.27869
92 3N26 ARG 3.27869
93 3KVY URA 3.27869
94 1ZPD CIT 3.27869
95 3HYW DCQ 3.27869
96 1ID0 ANP 3.28947
97 3I6B KDO 3.33333
98 1HBK MYR 3.37079
99 4BPM GSH 3.37079
100 4WGF HX2 3.41463
101 2BHW NEX 3.44828
102 2BHW XAT 3.44828
103 5UC9 MYR 3.53982
104 4OR7 25U 3.63636
105 1Q3A NGH 3.63636
106 1DQE BOM 3.64964
107 4V2O CLQ 3.65854
108 1CZA ADP 3.68852
109 3LXI CAM 3.68852
110 1MLD CIT 3.68852
111 3ZQE DXC 3.68852
112 4V3I ASP LEU THR ARG PRO 3.68852
113 4KCF AKM 3.68852
114 1A05 IPM 3.68852
115 1XX4 BAM 3.68852
116 4E90 7RG 3.68852
117 4ETZ C2E 3.68852
118 4UMJ BFQ 3.71622
119 5U83 ZN8 3.77358
120 1SO2 666 3.80952
121 5UC4 83S 4.09091
122 1XQP 8HG 4.09836
123 2BCG GER 4.09836
124 5LX9 OLB 4.09836
125 3CHT 4NB 4.09836
126 2E9L PLM 4.09836
127 1XMY ROL 4.09836
128 3O7U O7U 4.09836
129 5G57 6M5 4.09836
130 5EHR 5OD 4.09836
131 1XM4 PIL 4.09836
132 1XMU ROF 4.09836
133 4EXO PYR 4.10959
134 3N7S 3N7 4.34783
135 1MID LAP 4.3956
136 3TL1 JRO 4.40252
137 4OGQ 7PH 4.5082
138 4OGQ 1O2 4.5082
139 4OGQ UMQ 4.5082
140 3GFZ FMN 4.5082
141 4OGQ SQD 4.5082
142 5C2F JTH 4.5082
143 1EWF PC1 4.5082
144 3ETG GTP 4.5082
145 1W2D ADP 4.5082
146 5IM3 DTP 4.5082
147 2JC9 ADN 4.5082
148 3ETG GWD 4.5082
149 4O4Z N2O 4.54545
150 5UGW GSH 4.57143
151 5N18 8HZ 4.58716
152 4IBF 1D5 4.65116
153 1WEI ADE 4.88889
154 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 4.91803
155 4G86 BNT 4.91803
156 5B25 4QJ 4.91803
157 3LLI FAD 4.91803
158 5OKL PAM 4.91803
159 3EE4 MYR 4.91803
160 5ZKC 3C0 4.91803
161 1AUA BOG 4.91803
162 4YKI GLY 4.91803
163 1GPM AMP 4.91803
164 3BJC WAN 4.91803
165 3IA4 MTX 4.93827
166 3KO0 TFP 4.9505
167 5W7B MYR 4.96454
168 5XJ7 87O 4.97512
169 5HWK BEZ 5
170 2ZL4 ALA ALA ALA ALA 5.10204
171 6FS0 E4W 5.11628
172 1XZ3 ICF 5.17241
173 1YKD CMP 5.27638
174 3E70 GDP 5.32787
175 4OIC A8S 5.32787
176 3B99 U51 5.32787
177 4Q86 AMP 5.32787
178 3LDW ZOL 5.32787
179 4LH7 NMN 5.32787
180 3SQP 3J8 5.32787
181 4F7E 0SH 5.32787
182 5K53 STE 5.34351
183 4QC6 30N 5.58659
184 3KC1 2T6 5.63798
185 4DS8 A8S 5.7377
186 3X01 AMP 5.7377
187 5JO1 6LM 5.7377
188 4EIL FOL 5.7377
189 2WPW ACO 5.7377
190 2WPX ACO 5.7377
191 5CHR 4NC 5.83942
192 4NB5 2JT 5.84795
193 2WT9 NIO 5.95745
194 3TTZ 07N 6.06061
195 5M37 9SZ 6.08696
196 6C1R EFD 6.14754
197 2HU5 GLY PHE 6.14754
198 3HR1 PF9 6.14754
199 2QZT PLM 6.30631
200 5YZC 95C 6.38298
201 5MOB A8S 6.46552
202 1SBR VIB 6.5
203 6DIO CIT 6.55738
204 5AZC PGT 6.55738
205 1I0B PEL 6.55738
206 5CX6 CDP 6.55738
207 2YFB SIN 6.55738
208 4L80 OXL 6.55738
209 5OSW DIU 6.55738
210 5V3Y 5V8 6.55738
211 3B9Z CO2 6.55738
212 1J78 VDY 6.55738
213 5OSW AE4 6.55738
214 1J78 OLA 6.55738
215 3Q2H QHF 6.55738
216 5OCM 9RH 6.55738
217 5V13 JH3 6.55738
218 1S8G DAO 6.61157
219 2FP2 TSA 6.62651
220 4EJ1 FOL 6.71642
221 5V4R MGT 6.79012
222 1JR8 FAD 6.83761
223 3GKJ HC3 6.89655
224 3O01 DXC 6.96721
225 2JHP GUN 6.96721
226 4NKW PLO 6.96721
227 6CGN DA 6.96721
228 3GQT UFO 6.96721
229 3V1S 0LH 6.96721
230 4XCP PLM 7.05882
231 5WRE 7TL 7.09677
232 6BLD DXJ 7.1599
233 3TDC 0EU 7.37705
234 6CB2 OLC 7.37705
235 3QCP FAD 7.37705
236 3T58 FAD 7.37705
237 5OLK DTP 7.37705
238 4GVF NDG 7.37705
239 4GVF NAG 7.37705
240 3GUZ PAF 7.38636
241 3HP9 CF1 7.46888
242 3G4Q MCH 7.53425
243 5LWY OLB 7.56302
244 5U9J GER 7.69231
245 4XUB 43D 7.69231
246 2UW1 GVM 7.78689
247 2BD0 BIO 7.78689
248 1VAY AZA 7.78689
249 2QJY UQ2 7.78689
250 3V8S 0HD 7.78689
251 2RKN LP3 7.79221
252 1N8V BDD 8.03571
253 2GNK ATP 8.03571
254 4RC8 STE 8.10811
255 3RLF MAL 8.19672
256 1XI9 PLP 8.19672
257 1NF8 BOG 8.21256
258 1G27 BB1 8.33333
259 2Z6C FMN 8.52713
260 2OZ5 7XY 8.60656
261 4I90 CHT 8.60656
262 4CCW VKC 8.60656
263 1UBY DMA 8.60656
264 5MWE TCE 8.64198
265 5OCA 9QZ 8.75576
266 3OGN 3OG 8.87097
267 5MBC FMN 9.01639
268 2RH1 CAU 9.01639
269 2RH1 CLR 9.01639
270 6MVU K4V 9.01639
271 4HBM 0Y7 9.16667
272 4V1F BQ1 9.30233
273 5HCN DAO 9.42623
274 1RL4 BL5 9.57447
275 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 9.62343
276 1X0P FAD 9.79021
277 5WSY 7UC 9.82659
278 1ZED PNP 9.83607
279 5IUY BOG 9.83607
280 2BYC FMN 10.219
281 2Z9I GLY ALA THR VAL 10.2459
282 1T0S BML 10.2459
283 4WT2 3UD 10.4762
284 2WDQ CBE 10.5042
285 5NM7 GLY 10.6557
286 4L77 CNL 10.6557
287 1XVB 3BR 11.0656
288 3AB4 THR 11.0656
289 4OAS 2SW 11.4583
290 4DE3 DN8 11.4754
291 4DDY DN6 11.4754
292 1RV1 IMZ 11.7647
293 2GN2 C5P 11.8852
294 3NJQ NJQ 11.9171
295 4P3H 25G 11.9171
296 2HJ3 FAD 12
297 3BRN SRO 12.1019
298 2GBB CIT 12.1795
299 2J8R MSL 12.2093
300 6B21 C9V 12.2951
301 5MTE BB2 12.4088
302 1DTL BEP 12.7049
303 5N8V KZZ 13.0435
304 2Y69 CHD 13.5135
305 1Q7E MET 13.9344
306 2UYN 2KT 13.9535
307 5Y02 HBX 14.0187
308 4YMU ARG 14.0909
309 4IA6 EIC 14.3443
310 1MFI FHC 14.9123
311 1ZEI CRS 15.0943
312 2HHP FLC 15.1639
313 5KOR GDP 15.1639
314 5W97 CHD 15.2542
315 5Z84 CHD 15.2542
316 5ZCO CHD 15.2542
317 5ZCO PEK 15.2542
318 3JRS A8S 15.3846
319 2P1C GG3 15.5738
320 3KDJ A8S 15.8416
321 1TW4 CHD 16
322 4I67 G G G RPC 16.092
323 1TV5 N8E 17.623
324 4RJD TFP 18.1818
325 2V5E SCR 18.8119
326 4YSX E23 18.8525
327 4ZGM 32M 18.8525
328 3G5K BB2 19.1257
329 3ZCB ATP 19.1919
330 5FH7 5XL 19.3548
331 4DOL PLM 19.3548
332 4JX1 CAH 19.469
333 5C1M OLC 20.8
334 5C1M 4VO 20.8
335 2VWA PTY 21.7822
336 4B1V LAB 21.875
337 3EYK EYK 22.093
338 5APK 76E 25.4098
339 5NTW 98N 25.8197
340 5M36 9SZ 26.3158
341 5NTP 98E 26.4706
342 5IXK 6EW 27.193
343 4S15 4D8 27.8689
344 2AX9 BHM 31.1475
345 3V49 PK0 31.1475
346 1M13 HYF 31.1475
347 2A3I C0R 31.9672
348 5HCV 60R 31.9672
349 5MWY YNU 31.9672
350 4UDB CV7 32.377
351 5L7G 6QE 32.377
352 2O4J VD4 32.377
353 3VRV YSD 32.377
354 5L7G LYS SER LEU LEU GLN GLN LEU LEU THR GLU 32.377
355 3SP6 IL2 34.0164
356 1K7L 544 34.0164
357 3KDU NKS 34.0164
358 1NHZ 486 34.4262
359 1M2Z DEX 34.4262
360 1M2Z BOG 34.4262
361 3BQD DAY 34.4262
362 3RY9 1CA 34.8361
363 4LSJ LSJ 34.8361
364 2Q1H AS4 35.2459
365 2PRG BRL 35.2459
366 2HFP NSI 35.2459
367 1SR7 MOF 35.6557
368 4OAR 2S0 35.6557
369 3GN8 DEX 36.0656
370 5UFS 1TA 36.0656
371 3BEJ MUF 36.1345
372 3ET1 ET1 37.5
373 3RUU 37G 37.5546
374 1N46 PFA 37.7049
375 3DCT 064 38.0952
376 5UC1 486 38.2883
377 4OIV XX9 38.4956
378 3L0E G58 38.5246
379 3KFC 61X 39.3443
380 2NPA MMB 40
381 4DM8 REA 40.1639
382 3IPQ 965 40.1639
383 3KMZ EQO 40.5738
384 5K13 6Q7 40.5738
385 3JZB 4HY 40.9836
386 6FX0 E9T 41.8033
387 5E7V M7E 42.623
388 4Q0A 4OA 42.623
389 4P6X HCY 42.8571
390 5G5W R8C 42.8571
391 2R40 EPH 44.6721
392 2R40 20E 44.6721
393 3KMR EQN 46.1538
394 5LGA 6VH 46.1538
395 3FEI CTM 46.1538
396 5TWO 7MV 46.6667
397 4P6W MOF 50
398 4E2J MOF 50
399 6ESN BWE 50
400 4DK7 0KS 50
Pocket No.: 2; Query (leader) PDB : 2E2R; Ligand: 2OH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2e2r.bio1) has 35 residues
No: Leader PDB Ligand Sequence Similarity
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