Receptor
PDB id Resolution Class Description Source Keywords
2P39 1.5 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF HUMAN FGF23 HOMO SAPIENS ATYPICAL BETA-TREFOIL FOLD SIGNALING PROTEIN
Ref.: MOLECULAR INSIGHTS INTO THE KLOTHO-DEPENDENT, ENDOCRINE MODE OF ACTION OF FIBROBLAST GROWTH FACTOR 19 SUBFAMILY MEMBERS. MOL.CELL.BIOL. V. 27 3417 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SCR A:1;
Valid;
none;
submit data
982.802 C12 H22 O35 S8 C([C@...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2P39 1.5 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF HUMAN FGF23 HOMO SAPIENS ATYPICAL BETA-TREFOIL FOLD SIGNALING PROTEIN
Ref.: MOLECULAR INSIGHTS INTO THE KLOTHO-DEPENDENT, ENDOCRINE MODE OF ACTION OF FIBROBLAST GROWTH FACTOR 19 SUBFAMILY MEMBERS. MOL.CELL.BIOL. V. 27 3417 2007
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 2P39 - SCR C12 H22 O35 S8 C([C@@H]1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 2P39 - SCR C12 H22 O35 S8 C([C@@H]1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 2P39 - SCR C12 H22 O35 S8 C([C@@H]1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SCR; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 SCR 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2P39; Ligand: SCR; Similar sites found: 15
This union binding pocket(no: 1) in the query (biounit: 2p39.bio1) has 11 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4J4H 1J1 0.02875 0.42817 2.58065
2 4J4H NAI 0.0342 0.42379 2.58065
3 5GM9 CBK 0.01515 0.42211 3.87097
4 2WCV FUC 0.01595 0.4293 4.28571
5 4R81 FMN 0.02246 0.4036 5.16129
6 5MSO NAP 0.03902 0.40011 5.80645
7 3GGO ENO 0.03825 0.40678 7.09677
8 2LBD REA 0.02494 0.40858 8.3871
9 1TI7 NAP 0.03993 0.40091 8.3871
10 5J60 FAD 0.04957 0.40017 8.3871
11 1T36 U 0.01039 0.41576 10.9677
12 5G3U FDA 0.008234 0.44949 11.6129
13 4YSX FAD 0.01069 0.44153 12.2581
14 1PCA CIT 0.003215 0.42014 16.129
15 3K1X DBX 0.003707 0.41475 32.3077
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