-->
Receptor
PDB id Resolution Class Description Source Keywords
2P39 1.5 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF HUMAN FGF23 HOMO SAPIENS ATYPICAL BETA-TREFOIL FOLD SIGNALING PROTEIN
Ref.: MOLECULAR INSIGHTS INTO THE KLOTHO-DEPENDENT, ENDOCRINE MODE OF ACTION OF FIBROBLAST GROWTH FACTOR 19 SUBFAMILY MEMBERS. MOL.CELL.BIOL. V. 27 3417 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SCR A:1;
Valid;
none;
submit data
982.802 C12 H22 O35 S8 C([C@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2P39 1.5 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF HUMAN FGF23 HOMO SAPIENS ATYPICAL BETA-TREFOIL FOLD SIGNALING PROTEIN
Ref.: MOLECULAR INSIGHTS INTO THE KLOTHO-DEPENDENT, ENDOCRINE MODE OF ACTION OF FIBROBLAST GROWTH FACTOR 19 SUBFAMILY MEMBERS. MOL.CELL.BIOL. V. 27 3417 2007
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 2P39 - SCR C12 H22 O35 S8 C([C@@H]1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 2P39 - SCR C12 H22 O35 S8 C([C@@H]1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 2P39 - SCR C12 H22 O35 S8 C([C@@H]1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SCR; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 SCR 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2P39; Ligand: SCR; Similar sites found with APoc: 214
This union binding pocket(no: 1) in the query (biounit: 2p39.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 1E6E FAD None
2 2AZC 3TL None
3 4KOT CE3 None
4 2C0U FAD NBT None
5 1BZY IMU None
6 3EFS BTN None
7 1Z4O GL1 1.29032
8 1S17 GNR 1.29032
9 2C7G ODP 1.93548
10 2C7G FAD 1.93548
11 4YBN FAD 1.93548
12 1LDN NAD 1.93548
13 4B5P ACO 1.93548
14 1OMO NAD 1.93548
15 3UIM ANP 1.93548
16 4OSP NAP 1.93548
17 6CI9 NAP 1.93548
18 3HDY FDA 2.58065
19 3HDY GDU 2.58065
20 3HDY FAD 2.58065
21 1MUU NAD 2.58065
22 1MV8 NAD 2.58065
23 4J4H NAI 2.58065
24 4J4H 1J1 2.58065
25 4JK3 NAD 2.58065
26 1N7G GDR 2.58065
27 5H2U 1N1 2.58065
28 3N39 FMN 2.58065
29 1DIG NAP 2.58065
30 1DIG L37 2.58065
31 5FIT AP2 2.72109
32 1VPE ANP 3.22581
33 4M7V NAP 3.22581
34 3LXD FAD 3.22581
35 4B0T ADP 3.22581
36 2YVO AMP 3.22581
37 2RGH FAD 3.22581
38 1GV0 NAD 3.22581
39 1LTH NAD 3.22581
40 1C1X NAD 3.22581
41 2PS1 PRP 3.22581
42 1BW9 NAD 3.22581
43 3AB1 FAD 3.22581
44 2PS1 ORO 3.22581
45 3WDM ADN 3.22581
46 1NV8 MEQ 3.22581
47 1NV8 SAM 3.22581
48 1BXG NAD 3.22581
49 4GKV NAD 3.57143
50 1A5Z NAD 3.87097
51 3Q3C NAD 3.87097
52 5GM9 CBK 3.87097
53 1M2K APR 3.87097
54 4MP8 NAD 3.87097
55 4MP8 MLI 3.87097
56 4AMV F6R 3.87097
57 2C1X UDP 3.87097
58 1MOQ GLP 3.87097
59 4PVD NDP 3.87097
60 3VEH 0GA 3.87097
61 1NAA 6FA 3.87097
62 2GKS ADP 3.87097
63 2F1K NAP 4.51613
64 2D1S SLU 4.51613
65 1GTE FAD 4.51613
66 4M52 FAD 4.51613
67 4M52 M52 4.51613
68 3GF4 UPG 4.51613
69 3GF4 FAD 4.51613
70 3LAD FAD 4.51613
71 4Z87 5GP 4.51613
72 1YKJ FAD 4.51613
73 5HSA FAS 4.51613
74 1N9G NAP 4.51613
75 1COY FAD 4.51613
76 2CSN CKI 4.51613
77 2GLX NDP 4.51613
78 1P9B GDP 4.51613
79 2DKH FAD 4.51613
80 2DKH 3HB 4.51613
81 4WAS NAP 4.51613
82 6EL3 NAP 4.51613
83 2F59 INI 4.51613
84 6CEP NAD 4.51613
85 2OHH FMN 4.51613
86 3QJ4 FAD 5.16129
87 4C12 ADP 5.16129
88 4C12 UML 5.16129
89 4Z0G 5GP 5.16129
90 1D4D FAD 5.16129
91 2GJN NIS 5.16129
92 4PIV NDP 5.16129
93 4AVB ACO 5.16129
94 4R81 FMN 5.16129
95 1X9I G6Q 5.16129
96 2GJN FMN 5.16129
97 6B3V ANP 5.80645
98 2VTD LKM 5.80645
99 1J49 NAD 5.80645
100 1OBB NAD 5.80645
101 2XNJ NAP 5.80645
102 1NST A3P 5.80645
103 2V2V V12 5.80645
104 4PTZ FMN 5.80645
105 3U2U UDP 5.80645
106 3VPH OXM 5.80645
107 3VPH NAD 5.80645
108 5TUK FAD 5.80645
109 4RGQ 13P 5.80645
110 5MSO NAP 5.80645
111 2VVL FAD 6.45161
112 2VVM FAD 6.45161
113 4ZCC FAD 6.45161
114 3CTY FAD 6.45161
115 1XHC FAD 6.45161
116 1FIQ SAL 6.45161
117 1FIQ MTE 6.45161
118 1QS8 IVA VAL VAL STA ALA STA 6.45161
119 3WG6 NDP 6.45161
120 1ZVW PRP 6.45161
121 5OE4 3UK 6.45161
122 2YG3 FAD 6.45161
123 2HJR APR 6.45161
124 4AF0 IMP 6.45161
125 2G5C NAD 7.09677
126 2C6Q NDP 7.09677
127 5FB3 NDP 7.09677
128 1HYH NAD 7.09677
129 1RM0 NAI 7.09677
130 1QO8 FAD 7.09677
131 3GGO ENO 7.09677
132 3GGO NAI 7.09677
133 4ZSY RW2 7.09677
134 5CAE SIN 7.09677
135 5CAE COA 7.09677
136 1SC6 NAD 7.09677
137 4LTN NAI 7.09677
138 2C6Q IMP 7.09677
139 1AE1 NAP 7.09677
140 2DPM SAM 7.09677
141 1DJL NAP 7.74194
142 5JE8 NAD 7.74194
143 1D4O NAP 7.74194
144 4OM8 NAD 7.74194
145 3HBF MYC 7.74194
146 3HBF UDP 7.74194
147 4XYB NDP 7.74194
148 5WKC FAD 7.74194
149 1V6A TRE 7.74194
150 5J5R 6G1 8.3871
151 5J5R IMP 8.3871
152 2CVZ NDP 8.3871
153 4IXH IMP 8.3871
154 2LBD REA 8.3871
155 3MKH FAD 8.3871
156 1NVM NAD 8.3871
157 1FCZ 156 8.3871
158 1TI7 NAP 8.3871
159 1WP4 NDP 8.3871
160 5J60 FAD 8.3871
161 3FC4 EDO 9.03226
162 1JV1 UD1 9.03226
163 1QRP HH0 9.03226
164 5TC4 NAD 9.03226
165 1VHD NAP 9.03226
166 3OID NDP 9.67742
167 1RSG FAD 9.67742
168 4C3Y FAD 9.67742
169 4C3Y ANB 9.67742
170 2YAB AMP 9.67742
171 1I8T FAD 10.3226
172 4MOP 2H5 10.3226
173 3CIP ATP 10.9375
174 3RNM FAD 10.9677
175 1T36 U 10.9677
176 2F5Z FAD 10.9677
177 5Y77 FAD 10.9677
178 4CBU ATP 11.0236
179 5ZYN FAD 11.6129
180 5G3U ITW 11.6129
181 5G3U FDA 11.6129
182 4U8P UDP 11.6129
183 4U8P FDA 11.6129
184 4TXI FAD 11.6129
185 1UP7 NAD 11.6129
186 5YU3 NAD 11.6129
187 5YU3 PRO 11.6129
188 5ZI2 ADP 11.6129
189 4YSX FAD 12.2581
190 4DSG UDP 12.2581
191 4DSG FAD 12.2581
192 1E8C UAG API 12.9032
193 2A8X FAD 12.9032
194 2GMH FAD 12.9032
195 2QTR NXX 12.9032
196 1P6D 3PC 12.9032
197 1HXD BTN 12.9032
198 2VUT NAD 13.9535
199 2CDC XYP 14.1935
200 2CDC NAP 14.1935
201 2BEK ATP 14.1935
202 1LLU NAD 14.8387
203 1PCA CIT 16.129
204 2B5W NAP 17.4194
205 1DJN ADP 18.7097
206 1O94 ADP 18.7097
207 4LRZ ADP 18.7097
208 1X7D ORN 19.3548
209 1X7D NAD 19.3548
210 4RPL 3UC 20
211 2VHW NAI 24.5161
212 3T31 DCQ 31.6129
213 3T31 FAD 31.6129
214 3K1X DBX 32.3077
APoc FAQ
Feedback