Receptor
PDB id Resolution Class Description Source Keywords
2ORZ 2.15 Å NON-ENZYME: OTHER STRUCTURAL BASIS FOR LIGAND BINDING AND HEPARIN MEDIATED ACT NEUROPILIN RATTUS NORVEGICUS NEUROPILIN VEGF TUFTSIN SIGNALING PROTEIN MEMBRANE PROTE
Ref.: STRUCTURAL BASIS FOR LIGAND AND HEPARIN BINDING TO NEUROPILIN B DOMAINS. PROC.NATL.ACAD.SCI.USA V. 104 6152 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
THR LYS PRO ARG B:2;
 Valid;
 none;
 submit data
401.512 n/a O=C([...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2ORZ 2.15 Å NON-ENZYME: OTHER STRUCTURAL BASIS FOR LIGAND BINDING AND HEPARIN MEDIATED ACT NEUROPILIN RATTUS NORVEGICUS NEUROPILIN VEGF TUFTSIN SIGNALING PROTEIN MEMBRANE PROTE
Ref.: STRUCTURAL BASIS FOR LIGAND AND HEPARIN BINDING TO NEUROPILIN B DOMAINS. PROC.NATL.ACAD.SCI.USA V. 104 6152 2007
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1579 families.
1 2ORZ - THR LYS PRO ARG n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1312 families.
1 2ORZ - THR LYS PRO ARG n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1130 families.
1 2ORZ - THR LYS PRO ARG n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: THR LYS PRO ARG; Similar ligands found: 72
No: Ligand ECFP6 Tc MDL keys Tc
1 THR LYS PRO ARG 1 1
2 LYS PRO LYS 0.780822 0.886792
3 DPN PRO ARG 0.662921 0.945455
4 ARG PRO LYS ARG ILE ALA 0.609524 0.898305
5 ARG PRO LYS PRO LEU VAL ASP PRO 0.588235 0.85
6 LYS PRO VAL LEU ARG THR ALA 0.585586 0.84127
7 SER PRO LYS ARG ILE ALA 0.582524 0.868852
8 LYS PRO 0.546667 0.886792
9 5JP PRO LYS ARG ILE ALA 0.54 0.825397
10 CYS THR PRO SER ARG 0.528846 0.825397
11 ALA PRO PRO PRO ARG PRO PRO LYS PRO 0.518868 0.894737
12 GLU PRO GLY GLY SER ARG 0.518868 0.883333
13 ARG LEU PRO ALA LYS ALA PRO LEU LEU 0.5 0.868852
14 ARG PRO GLN VAL PRO LEU ARG PRO MET 0.495935 0.815385
15 TYR PRO LYS ARG ILE ALA 0.495868 0.815385
16 ARG GLN PRO ALA LYS ALA PRO LEU LEU 0.491803 0.854839
17 ARG PRO PRO GLY PHE SER PRO PHE ARG 0.488636 0.927273
18 ARG PRO PRO GLY PHE THR PRO PHE ARG 0.488636 0.927273
19 LYS PRO HIS SER ASP 0.482143 0.738462
20 DPN PRO DAR DTH NH2 0.481481 0.822581
21 VAL PRO PRO PRO ARG PRO PRO PRO PRO GLU 0.481481 0.913793
22 DPN PRO DAR CYS NH2 0.481132 0.862069
23 1IP CYS PHE SER LYS PRO ARG 0.48062 0.791045
24 PHE PRO ARG 0.48 0.909091
25 LEU ASP PRO ARG 0.47619 0.866667
26 ARG PRO ARG PRO ASP ASP LEU GLU ILE 0.47541 0.84127
27 LYS ARG ARG ARG HIS PRO SER 0.475 0.83871
28 GLY PRO ARG PRO 0.473684 0.910714
29 GLU LYS PRO SER SER SER 0.470588 0.770492
30 DPN PRO DAR ILE NH2 0.46789 0.833333
31 GLN PRO PRO VAL PRO PRO GLN ARG PRO MET 0.464 0.815385
32 LYS ARG LYS 0.45977 0.759259
33 LYS ARG ARG ARG HIS PRO SER GLY 0.459677 0.8
34 ASN PRO ARG ALA MET GLN ALA LEU LEU 0.44 0.80303
35 ALA PRO ASP THR ARG PRO 0.438596 0.815385
36 ARG PRO MET THR PHE LYS GLY ALA LEU 0.438356 0.746479
37 ACE PRO ARG TYR 0.438202 0.892857
38 ACE PRO ARG ASN 0.438202 0.892857
39 PRO PRO LYS ARG ILE ALA 0.438017 0.898305
40 3BY PRO LYS ARG ILE ALA 0.438017 0.828125
41 ACE GLN GLU ARG GLU VAL PRO CYS 0.435897 0.883333
42 ALA PRO ASP THR ARG PRO ALA PRO 0.435897 0.815385
43 LYS ALA PRO ARG ALY GLN LEU ALA THR LYS 0.435897 0.836066
44 ARG PRO MET THR TYR LYS GLY ALA LEU 0.435374 0.716216
45 ASN ARG PRO ILE LEU SER LEU 0.433333 0.776119
46 ALA MET ALA PRO ARG THR LEU LEU LEU 0.427419 0.779412
47 VAL MET ALA PRO ARG ALA LEU LEU LEU 0.42623 0.84127
48 THR PRO ARG ARG SER MLZ SER ALA 0.426087 0.764706
49 ARG PRO PRO ILE PHE ILE ARG ARG LEU 0.424242 0.84127
50 ALA ILE MET PRO ALA ARG PHE TYR PRO LYS 0.423841 0.736111
51 SER ALA PRO ASP THR ARG PRO ALA 0.422764 0.80303
52 SER SER GLY LYS VAL PRO LEU 0.421053 0.734375
53 HIS HIS ALA SER PRO ARG LYS 0.421053 0.8125
54 ALA PHE ARG ILE PRO LEU THR ARG 0.421053 0.791045
55 PHE ASN ARG PRO VAL 0.420168 0.825397
56 ASN ARG PRO VAL TYR ILE PRO ARG PRO PRO 0.419847 0.776119
57 ARG ARG ARG GLU ARG SER PRO THR ARG 0.419355 0.84127
58 VAL LYS PRO GLY 0.418367 0.810345
59 ARG PRO PRO GLY PHE 0.413793 0.864407
60 ALA ARG 0.4125 0.690909
61 GLY GLU ARG THR ILE PRO ILE THR ARG GLU 0.409449 0.815385
62 ILE PRO ILE 0.409091 0.77193
63 GLU ARG THR ILE PRO ILE THR ARG GLU 0.408333 0.8125
64 TYR MET ASP PHE ASP ASP ASP ILE PRO PHE 0.408163 0.762712
65 ALA ASN SER ARG LEU PRO THR SER ILE ILE 0.406504 0.787879
66 LYS VAL PRO ARG ASN GLN ASP TRP LEU 0.405229 0.768116
67 GLY SER ASP PRO PHE LYS 0.405172 0.746032
68 ALA ARG MLZ SER ALA PRO ALA THR 0.404762 0.779412
69 MET CYS PRO ARG MET THR ALA VAL MET 0.402985 0.779412
70 SER PRO ARG LEU PRO LEU LEU GLU SER 0.401709 0.864407
71 ARG VAL ALA SER PRO THR SER GLY VAL 0.4 0.8
72 ARG THR PRO SEP LEU PRO THR 0.4 0.732394
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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