-->
Receptor
PDB id Resolution Class Description Source Keywords
2JLR 2 Å EC: 3.4.21.91 DENGUE VIRUS 4 NS3 HELICASE IN COMPLEX WITH AMPPNP DENGUE VIRUS 4 RIBONUCLEOPROTEIN NUCLEOTIDE-BINDING HELICASE PROTEASE HYDROLASE ATP ANALOG TRANSFERASE VIRAL NUCLEOPROTEIN ENDOPLASMIC RETICULUM CLEAVAGE ON PAIR OF BASIC RESIDUES MULTIFUNCTIONAL ENZYME TRANSCRIPTION REGULATION NUCLEOTIDYLTRANSFERASE NS3 HELICASE STRUCTURE VIRION ATPNUCLEUS MEMBRANE SECRETED ATP-BINDING RNA-BINDING FLAVIVIRUSES GLYCOPROTEIN RNA-DIRECTED RNA POLYMERASE RNREPLICATION SERINE PROTEASE ENVELOPE PROTEIN DENGUE VIRUMETAL-BINDING TRANSMEMBRANE TRANSCRIPTION PHOSPHOPROTEINPROTEIN
Ref.: INSIGHTS INTO RNA UNWINDING AND ATP HYDROLYSIS BY T FLAVIVIRUS NS3 PROTEIN. EMBO J. V. 27 3209 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP A:1620;
Valid;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
MN A:1619;
Part of Protein;
none;
submit data
54.938 Mn [Mn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2JLR 2 Å EC: 3.4.21.91 DENGUE VIRUS 4 NS3 HELICASE IN COMPLEX WITH AMPPNP DENGUE VIRUS 4 RIBONUCLEOPROTEIN NUCLEOTIDE-BINDING HELICASE PROTEASE HYDROLASE ATP ANALOG TRANSFERASE VIRAL NUCLEOPROTEIN ENDOPLASMIC RETICULUM CLEAVAGE ON PAIR OF BASIC RESIDUES MULTIFUNCTIONAL ENZYME TRANSCRIPTION REGULATION NUCLEOTIDYLTRANSFERASE NS3 HELICASE STRUCTURE VIRION ATPNUCLEUS MEMBRANE SECRETED ATP-BINDING RNA-BINDING FLAVIVIRUSES GLYCOPROTEIN RNA-DIRECTED RNA POLYMERASE RNREPLICATION SERINE PROTEASE ENVELOPE PROTEIN DENGUE VIRUMETAL-BINDING TRANSMEMBRANE TRANSCRIPTION PHOSPHOPROTEINPROTEIN
Ref.: INSIGHTS INTO RNA UNWINDING AND ATP HYDROLYSIS BY T FLAVIVIRUS NS3 PROTEIN. EMBO J. V. 27 3209 2008
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2JLR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 2JLS - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 250 families.
1 2JLR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 2JLS - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 5Y6N - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
4 5GJC - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
5 5Y6M - ADP AF3 n/a n/a
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 204 families.
1 2JLR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 2JLS - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
3 5Y6N - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
4 5GJC - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
5 5Y6M - ADP AF3 n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 373
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 AP5 0.802632 0.945205
5 ADP 0.802632 0.972222
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 HEJ 0.772152 0.972222
9 ATP 0.772152 0.972222
10 AT4 0.769231 0.933333
11 AN2 0.769231 0.986111
12 5FA 0.7625 0.972222
13 AQP 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 AR6 0.740741 0.945205
18 APR 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 SAP 0.731707 0.921053
22 AGS 0.731707 0.921053
23 A 0.723684 0.944444
24 AMP 0.723684 0.944444
25 ATF 0.717647 0.933333
26 ADX 0.716049 0.851852
27 CA0 0.716049 0.92
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 AP2 0.679012 0.933333
33 A12 0.679012 0.933333
34 APC 0.678571 0.933333
35 T99 0.674419 0.933333
36 TAT 0.674419 0.933333
37 A22 0.674157 0.958904
38 SRA 0.670886 0.894737
39 SRP 0.670455 0.883117
40 5AL 0.666667 0.906667
41 A1R 0.659341 0.884615
42 ADQ 0.659341 0.92
43 A3R 0.659341 0.884615
44 3OD 0.648936 0.92
45 BIS 0.648936 0.909091
46 5SV 0.648352 0.82716
47 9X8 0.645161 0.896104
48 OAD 0.645161 0.92
49 25L 0.642105 0.958904
50 AMO 0.641304 0.907895
51 G5P 0.636364 0.897436
52 DLL 0.634409 0.906667
53 AHX 0.634409 0.897436
54 00A 0.634409 0.860759
55 ADV 0.632184 0.907895
56 RBY 0.632184 0.907895
57 ADP PO3 0.632184 0.917808
58 NB8 0.631579 0.897436
59 25A 0.630435 0.945205
60 OOB 0.630435 0.906667
61 8QN 0.630435 0.906667
62 G3A 0.626263 0.897436
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 TXA 0.614583 0.907895
67 1ZZ 0.614583 0.819277
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 9ZD 0.612903 0.909091
71 9ZA 0.612903 0.909091
72 3UK 0.610526 0.894737
73 SON 0.604651 0.907895
74 ADP ALF 0.604396 0.848101
75 ALF ADP 0.604396 0.848101
76 PR8 0.604167 0.829268
77 B5V 0.604167 0.883117
78 WAQ 0.604167 0.860759
79 4UV 0.6 0.871795
80 GAP 0.6 0.87013
81 PTJ 0.597938 0.873418
82 FYA 0.597938 0.881579
83 VO4 ADP 0.597826 0.906667
84 ADP VO4 0.597826 0.906667
85 LMS 0.597561 0.829268
86 UP5 0.596154 0.896104
87 FA5 0.59596 0.883117
88 YAP 0.59596 0.871795
89 PAP 0.595506 0.958333
90 A4P 0.59434 0.823529
91 XAH 0.59 0.841463
92 4UU 0.588235 0.871795
93 AFH 0.588235 0.8625
94 9SN 0.585859 0.85
95 2A5 0.58427 0.894737
96 T5A 0.583333 0.821429
97 DQV 0.582524 0.932432
98 NAI 0.580952 0.884615
99 B5M 0.58 0.871795
100 B5Y 0.58 0.871795
101 ITT 0.579545 0.917808
102 ATR 0.577778 0.944444
103 OMR 0.575472 0.831325
104 5AS 0.574713 0.781609
105 YLP 0.571429 0.8
106 48N 0.571429 0.873418
107 AP0 0.570093 0.873418
108 4TC 0.570093 0.873418
109 7D3 0.569767 0.881579
110 ADJ 0.568807 0.831325
111 GNP 0.568421 0.922078
112 9GM 0.568421 0.922078
113 DAL AMP 0.568421 0.881579
114 6V0 0.566038 0.873418
115 TXD 0.566038 0.884615
116 DND 0.566038 0.907895
117 NAX 0.566038 0.851852
118 4UW 0.566038 0.839506
119 NXX 0.566038 0.907895
120 XYA 0.565789 0.821918
121 RAB 0.565789 0.821918
122 ADN 0.565789 0.821918
123 AOC 0.564706 0.8
124 7D4 0.561798 0.881579
125 ADP BMA 0.561224 0.894737
126 TXE 0.560748 0.884615
127 TYM 0.560748 0.883117
128 GA7 0.557692 0.883117
129 YLC 0.555556 0.819277
130 YLB 0.555556 0.8
131 139 0.554545 0.851852
132 5N5 0.551282 0.797297
133 JB6 0.55 0.860759
134 LAQ 0.54717 0.819277
135 F2R 0.544643 0.843373
136 MYR AMP 0.544554 0.797619
137 5CD 0.544304 0.783784
138 A4D 0.544304 0.797297
139 80F 0.54386 0.821429
140 7MD 0.542857 0.864198
141 6AD 0.542553 0.886076
142 A2R 0.541667 0.958904
143 UPA 0.541284 0.884615
144 YLA 0.540541 0.8
145 A A 0.54 0.918919
146 BTX 0.539823 0.821429
147 COD 0.539823 0.793103
148 HFD 0.537634 0.921053
149 G5A 0.537634 0.781609
150 3DH 0.535714 0.753247
151 AYB 0.535714 0.790698
152 CNA 0.535714 0.907895
153 BT5 0.535088 0.811765
154 ATP A A A 0.533981 0.905405
155 IOT 0.531532 0.811765
156 MTA 0.53012 0.753247
157 3AM 0.529412 0.90411
158 A3P 0.52809 0.944444
159 PPS 0.526316 0.851852
160 NAD 0.526316 0.906667
161 EP4 0.52439 0.734177
162 7D5 0.52381 0.855263
163 AMP DBH 0.52381 0.87013
164 J7C 0.522727 0.75
165 A5A 0.520833 0.809524
166 EAD 0.520661 0.851852
167 TSB 0.520408 0.821429
168 AHZ 0.518519 0.797619
169 DTA 0.518072 0.766234
170 M2T 0.518072 0.716049
171 A3D 0.517241 0.894737
172 6RE 0.517241 0.740741
173 YLY 0.516949 0.790698
174 SSA 0.515464 0.802326
175 NA7 0.514852 0.933333
176 ARG AMP 0.514019 0.809524
177 AR6 AR6 0.514019 0.893333
178 7MC 0.513514 0.843373
179 A2P 0.511111 0.930556
180 52H 0.510204 0.781609
181 VMS 0.510204 0.790698
182 54H 0.510204 0.790698
183 TYR AMP 0.509434 0.848101
184 TAD 0.509259 0.8625
185 NAQ 0.508333 0.85
186 A3N 0.505618 0.766234
187 AV2 0.505155 0.893333
188 53H 0.50505 0.781609
189 5CA 0.50505 0.802326
190 8X1 0.50505 0.755556
191 ARU 0.504951 0.839506
192 ZID 0.504132 0.894737
193 P1H 0.504 0.831325
194 NAE 0.5 0.871795
195 3AT 0.5 0.945205
196 AVV 0.5 0.873418
197 P5A 0.495146 0.747253
198 NSS 0.49505 0.802326
199 LSS 0.49505 0.764045
200 DSZ 0.49505 0.802326
201 N0B 0.491803 0.8
202 AF3 ADP 3PG 0.491071 0.817073
203 NVA LMS 0.490196 0.755556
204 DAT 0.489362 0.881579
205 IMO 0.488889 0.90411
206 ZAS 0.488636 0.792208
207 FDA 0.488372 0.813953
208 NAJ PZO 0.487395 0.85
209 4TA 0.487179 0.788235
210 LPA AMP 0.486486 0.797619
211 LEU LMS 0.485437 0.755556
212 DTP 0.484536 0.881579
213 V3L 0.484536 0.945205
214 S4M 0.483516 0.651685
215 GJV 0.483516 0.731707
216 DZD 0.483051 0.8625
217 2AM 0.482759 0.917808
218 5AD 0.481013 0.726027
219 GSU 0.480769 0.781609
220 KAA 0.480769 0.755556
221 NDE 0.480315 0.907895
222 M24 0.479339 0.851852
223 MAO 0.478261 0.761905
224 NEC 0.477778 0.727273
225 DSH 0.477778 0.707317
226 FAS 0.477273 0.831325
227 FAD 0.477273 0.831325
228 RGT 0.476636 0.933333
229 9K8 0.47619 0.698925
230 G A A A 0.474576 0.85
231 0WD 0.474576 0.897436
232 FNK 0.474074 0.786517
233 5X8 0.473684 0.74359
234 6FA 0.473282 0.821429
235 NDC 0.472868 0.85
236 FB0 0.472868 0.786517
237 YSA 0.472222 0.781609
238 7DD 0.468085 0.958333
239 OVE 0.466667 0.881579
240 MHZ 0.463158 0.701149
241 8PZ 0.462963 0.802326
242 A G 0.462185 0.860759
243 AMP NAD 0.462185 0.881579
244 A3G 0.461538 0.779221
245 NAJ PYZ 0.459677 0.809524
246 6C6 0.459184 0.858974
247 SFG 0.458333 0.730769
248 U A G G 0.458333 0.860759
249 7D7 0.45679 0.723684
250 128 0.45614 0.8
251 SFD 0.455224 0.736842
252 6IA 0.454545 0.817073
253 DDS 0.454545 0.855263
254 GDP 0.454545 0.896104
255 ODP 0.453782 0.886076
256 NJP 0.453782 0.921053
257 7DT 0.453608 0.958333
258 A7D 0.452632 0.75641
259 Z5A 0.452381 0.802326
260 WSA 0.452174 0.790698
261 U A 0.45082 0.884615
262 7C5 0.45045 0.797468
263 FAY 0.449275 0.841463
264 NDP 0.449153 0.897436
265 SA8 0.44898 0.690476
266 A5D 0.44898 0.766234
267 71V 0.446809 0.884615
268 GGZ 0.446602 0.804878
269 RFL 0.446043 0.802326
270 2SA 0.445545 0.907895
271 SAI 0.444444 0.716049
272 GP3 0.444444 0.897436
273 SAH 0.444444 0.725
274 PO4 PO4 A A A A PO4 0.443396 0.878378
275 A A A 0.443396 0.881579
276 4YB 0.442478 0.764045
277 SMM 0.441176 0.670455
278 S7M 0.441176 0.674419
279 GTP 0.441176 0.896104
280 Y3J 0.440476 0.706667
281 SAM 0.44 0.674419
282 649 0.439655 0.747253
283 12D 0.438596 0.809524
284 A3S 0.4375 0.789474
285 NPW 0.436975 0.864198
286 GCP 0.436893 0.873418
287 AAT 0.435644 0.690476
288 GNH 0.435644 0.909091
289 EEM 0.435644 0.674419
290 ETB 0.435484 0.813953
291 DCA 0.435484 0.804598
292 N6P 0.433962 0.890411
293 NZQ 0.433333 0.886076
294 TXP 0.433333 0.897436
295 PGS 0.43299 0.860759
296 APU 0.432203 0.871795
297 PUA 0.432 0.8625
298 62F 0.431655 0.841463
299 F2N 0.431507 0.795455
300 DA 0.430108 0.855263
301 D5M 0.430108 0.855263
302 J7V 0.429688 0.813953
303 NIA 0.428571 0.848101
304 COA 0.428571 0.804598
305 6K6 0.428571 0.905405
306 A3T 0.428571 0.8
307 0T1 0.428571 0.804598
308 P5F 0.427586 0.804598
309 AAM 0.425532 0.944444
310 0UM 0.424528 0.682353
311 8Q2 0.423729 0.775281
312 G1R 0.423077 0.884615
313 AMZ 0.422222 0.891892
314 C2R 0.422222 0.88
315 A U 0.420168 0.848101
316 IDP 0.42 0.894737
317 GSP 0.419048 0.851852
318 30N 0.418605 0.736842
319 CAO 0.418605 0.777778
320 DG1 0.418605 0.897436
321 1DG 0.418605 0.897436
322 COS 0.418605 0.786517
323 AMX 0.418605 0.813953
324 TM1 0.418182 0.797619
325 A6D 0.416667 0.746988
326 K15 0.416667 0.666667
327 V1N 0.415929 0.893333
328 CMX 0.415385 0.804598
329 SCO 0.415385 0.804598
330 GEK 0.415094 0.719512
331 XNP 0.414634 0.851852
332 NHD 0.414634 0.881579
333 9JJ 0.413793 0.841463
334 AIR 0.413793 0.876712
335 COK 0.413534 0.786517
336 G2R 0.412844 0.8625
337 ACO 0.412214 0.777778
338 FAM 0.412214 0.786517
339 FCX 0.412214 0.777778
340 NAP 0.410853 0.92
341 FA9 0.409396 0.843373
342 SXZ 0.409091 0.694118
343 HAX 0.409091 0.806818
344 TAP 0.407692 0.884615
345 2MC 0.407407 0.752688
346 62X 0.407407 0.651685
347 GKE 0.40708 0.8625
348 GDC 0.40708 0.8625
349 GDD 0.40708 0.8625
350 3KK 0.406015 0.786517
351 FYN 0.406015 0.804598
352 NVA 2AD 0.405941 0.740741
353 NA0 0.40458 0.907895
354 101 0.404255 0.855263
355 G 0.40404 0.883117
356 5GP 0.40404 0.883117
357 HDV 0.403846 0.87013
358 MGP 0.403846 0.8625
359 OXK 0.402985 0.786517
360 MCD 0.402985 0.786517
361 CA6 0.402985 0.714286
362 SOP 0.402985 0.786517
363 3AD 0.402299 0.783784
364 S8M 0.401869 0.78481
365 YE1 0.40146 0.795455
366 NMX 0.4 0.782609
367 7RP 0.4 0.902778
368 2VA 0.4 0.779221
369 1VU 0.4 0.777778
370 CO6 0.4 0.786517
371 CMC 0.4 0.786517
372 6G0 0.4 0.8625
373 GMV 0.4 0.873418
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2JLR; Ligand: ANP; Similar sites found with APoc: 709
This union binding pocket(no: 1) in the query (biounit: 2jlr.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
1 1OYY AGS 1.10865
2 1SVM ATP 1.32626
3 6AU6 GDP 1.32626
4 1GPE FAD 1.33038
5 5J7X FAD 1.33038
6 2NCD ADP 1.42857
7 1KK1 GNP 1.46341
8 2GKS ADP 1.55211
9 5TSH ADP 1.55211
10 5TSH ANP 1.55211
11 4DCT GDP 1.55211
12 5IRN ADP 1.55211
13 1P3D ANP 1.55211
14 3KJI ADP 1.5748
15 2J5V PCA 1.63488
16 3QF7 ANP 1.64384
17 1GOJ ADP 1.69014
18 3LRE ADP 1.69014
19 4D81 ADP 1.76678
20 1OS1 PYR 1.77384
21 2CE7 ADP 1.77384
22 1OS1 ATP 1.77384
23 4C12 ADP 1.77384
24 4LC1 GDP 1.78042
25 1D2N ANP 1.83824
26 5GOE GDP 1.89573
27 4GOX A3P 1.91693
28 1TQ4 GDP 1.93705
29 6ACS CIT 1.93798
30 1G6H ADP 1.94553
31 5Z21 OXM 1.95531
32 2ZE7 DST 1.97628
33 2ZE7 AMP 1.97628
34 3HU3 AGS 1.99557
35 1IHU ADP 1.99557
36 4PFO ADP 1.99557
37 1YTM ATP 1.99557
38 1GQY ACP 1.99557
39 1J78 OLA 1.99557
40 1IHU AF3 1.99557
41 3QVV A3P 2.0339
42 3QVV 3QV 2.0339
43 2DPY ADP 2.05479
44 5H68 AGS 2.05882
45 4FRZ ADP 2.07254
46 2IYL GDP 2.11268
47 1PUJ GNP 2.12766
48 5G3Y ADP 2.21239
49 5DNC ASN 2.21729
50 4U8P FDA 2.21729
51 1Q19 SSC 2.21729
52 4P4T GDP 2.22222
53 3FWY ADP 2.2293
54 1XMV ADP 2.24719
55 1MKY GDP 2.2779
56 4PPF FLC 2.28571
57 1B0U ATP 2.29008
58 1ZIN AP5 2.30415
59 4TTQ ATP 2.32558
60 4LJ9 ACP 2.35988
61 1P72 ADP 2.39521
62 2OFW ADX 2.40385
63 5XQL C2E 2.4055
64 4RD0 GDP 2.40964
65 3VMF GTP 2.41287
66 3P4X ADP 2.42131
67 3TK1 GDP 2.42424
68 1W5T ANP 2.42718
69 1W5T ADP 2.42718
70 4H1V GNP 2.43902
71 5M04 GDP 2.5
72 5O3Q CMP 2.5
73 1EBF NAD 2.51397
74 6A20 ADP 2.51716
75 2ZB4 NAP 2.52101
76 2ZB4 5OP 2.52101
77 4WEI GLC GAL 2.52708
78 5U32 GDP 2.54237
79 1K6M AGS 2.5463
80 4OHY ANP 2.5522
81 2XTN GTP 2.5641
82 2VVG ADP 2.57143
83 4FCW ADP 2.57235
84 2IXE ATP 2.58303
85 1H65 GDP 2.59259
86 4R8L ASP 2.5974
87 5Z20 OXM 2.6087
88 2GQT FAD 2.61194
89 4QOS ADP 2.64151
90 2X77 GDP 2.6455
91 4JB1 NAP 2.64706
92 4JB1 FAD 2.64706
93 1WF3 GNP 2.65781
94 5I0H ADP BEF 2.66075
95 1WDT GTP 2.66075
96 2D7D ADP 2.66075
97 4YS0 ADP 2.66075
98 4KVA GTP 2.6699
99 1ZJ6 G3D 2.6738
100 1JJ7 ADP 2.69231
101 5EXT ADP 2.69231
102 4R43 GDP 2.71565
103 1Y63 ADP 2.71739
104 3DZD ADP 2.71739
105 2Q2Y ADP 2.7248
106 2Q2Y MKR 2.7248
107 3IIJ ADP 2.77778
108 3ZQ6 ADP ALF 2.77778
109 1NN5 ANP 2.7907
110 1NN5 2DT 2.7907
111 2PEZ DAT 2.7933
112 2PEZ GGZ 2.7933
113 5J1J ANP 2.80702
114 4XGU ADP 2.83019
115 5KSZ GCP 2.83019
116 1SVK ALF GDP 2.83286
117 3ZFD ANP 2.849
118 5JCP GDP ALF 2.86396
119 5K5Z ANP 2.86624
120 4QDI ATP 2.88248
121 1V8K ANP 2.92683
122 1G41 ADP 2.92793
123 5ZBR ANP 2.93333
124 4L9Z OXL 2.94985
125 3R7F CP 2.96053
126 3X1Z GNP 2.99401
127 2ZFI ADP 3.00546
128 3T1O GDP 3.0303
129 1OE0 TTP 3.04348
130 3TKL GTP 3.06122
131 5N69 ADP 3.10421
132 1X6V ADP 3.10421
133 4ZG4 VO4 ADP 3.10421
134 5MZN ADP 3.10421
135 4ZKD GDP 3.10421
136 5ZXD ATP 3.11355
137 4BFW ZVW 3.14465
138 5CK5 GDP 3.16456
139 4MKG AP5 3.22581
140 5WC2 ADP 3.24074
141 4DKX GDP 3.24074
142 1W0J ADP 3.30882
143 1W0J ADP BEF 3.30882
144 3B9Q MLI 3.31126
145 1ZCB GDP 3.31492
146 3SFV GDP 3.31492
147 3AB3 GDP 3.31492
148 1E2K TMC 3.32326
149 5YV5 ADP 3.32594
150 2ZPA ADP 3.32594
151 4YMU ATP 3.33333
152 1YZG GDP 3.35196
153 1NY5 ADP 3.35917
154 2FNA ADP 3.36134
155 2EFE GNH 3.37079
156 2RGX AP5 3.39806
157 5L3R GCP 3.41297
158 1GWN GTP 3.41463
159 1SKQ GDP 3.44828
160 1FP6 ADP 3.46021
161 3BY9 SIN 3.46154
162 5BYK OAQ 3.4749
163 5BYK A3P 3.4749
164 1G8S MET 3.47826
165 5Z69 AGS 3.49462
166 3UIE ANP 3.5
167 5XKT GNP 3.5
168 1UPT GTP 3.50877
169 2QG6 NMN 3.51759
170 4BAS GNP 3.51759
171 2F9L GDP 3.51759
172 5ZB0 ADP 3.53535
173 5ZB0 TYD 3.53535
174 2CHG ANP 3.53982
175 4A4Z ANP 3.54767
176 4IOK XPO 3.54767
177 4IOK ADP 3.54767
178 2J0W ASP 3.56347
179 4KVG GTP 3.57143
180 1U8Z GDP 3.57143
181 1SVI GDP 3.58974
182 1KAO GDP 3.59281
183 1IN4 ADP 3.59281
184 1NJF ADP 3.6
185 1NJF AGS 3.6
186 2D2F ADP 3.6
187 3H86 AP5 3.64583
188 3MD0 GDP 3.66197
189 1OIV GDP 3.66492
190 1OIX GDP 3.66492
191 3DKP ADP 3.67347
192 1S3G AP5 3.68664
193 1TAD ALF 3.7037
194 1TAD GDP 3.7037
195 2O66 FLC 3.7037
196 4JLV ADP 3.71747
197 3QXC ATP 3.71901
198 5EE5 GTP 3.75587
199 1LVK MNT BEF 3.7694
200 1R6B ADP 3.7694
201 3DC4 ADP 3.77907
202 2GDJ ANP 3.78788
203 1G3Q ADP 3.79747
204 1M7B GTP 3.80435
205 3DEF GDP 3.81679
206 4Y4V DAL 3.83481
207 2ORV 4TA 3.84615
208 3KC1 2T6 3.85757
209 1VKJ A3P 3.85965
210 1VG0 GDP 3.86473
211 1VG8 GNP 3.86473
212 2BEK ATP 3.89105
213 2JAQ DCP 3.90244
214 5EP2 AZU 3.90625
215 2WKQ GTP 3.91566
216 1LK7 DER 3.93013
217 5BXQ GDP 3.93701
218 5TIV A3P 3.95257
219 4LX0 BEF GDP 3.98126
220 2FSH ANP 3.99113
221 2C9O ADP 3.99113
222 1IBR GNP 3.99113
223 2YG3 FAD 3.99113
224 1BG2 ADP 4
225 2QEN ADP 4
226 2ZR9 DTP 4.01146
227 1LVG ADP 4.0404
228 4QM7 GTP 4.09357
229 2Y65 ADP 4.10959
230 5X40 ACP 4.10959
231 1ION ADP 4.11523
232 1Z0J GTP 4.11765
233 1YVD GNP 4.14201
234 4MKF AP5 4.14747
235 3T34 GDP 4.16667
236 3EWA ANP 4.21286
237 1DAR GDP 4.21286
238 4TMK T5A 4.22535
239 3Q9L ATP 4.23077
240 2XTZ GSP 4.23729
241 1OXV ANP 4.24929
242 3EZ2 ADP 4.27136
243 1VG1 GDP 4.32432
244 1VG9 GDP 4.32432
245 3COB ADP 4.33604
246 5W75 GDP 4.33673
247 4UXH T5A 4.34783
248 4ZNL BEF ADP 4.37956
249 2ZTS ADP 4.38247
250 1CR1 TTP 4.39189
251 3QKT ANP 4.42478
252 4WOP CTP 4.44444
253 2Y8E GNP 4.46927
254 1B7T ADP 4.48718
255 2WOJ ADP ALF 4.51977
256 4XTR ATP 4.51977
257 4XVU ATP 4.51977
258 4XTR ADP 4.51977
259 4LPS GDP 4.54545
260 1G6O ADP 4.54545
261 1Y3A GDP 4.55927
262 1YRB GDP 4.58015
263 1VHT BA3 4.58716
264 4AG5 ADP 4.59184
265 5HCN GCP 4.5977
266 1OFH ADP 4.5977
267 1W4R TTP 4.61538
268 3PQC GDP 4.61538
269 2OM2 GDP 4.61538
270 3TMK T5A 4.62963
271 2IMG MLT 4.63576
272 5IFS ADP 4.64135
273 6B4K ANP 4.65116
274 2IS6 ADP 4.65632
275 1XKV ATP 4.65632
276 4IHQ ADP 4.65632
277 2FAH GDP 4.65632
278 3QVP FAD 4.65632
279 1ZPD CIT 4.65632
280 3GJX GTP 4.65753
281 3LU1 NAD 4.67033
282 2HV8 GTP 4.6875
283 3Q85 GNP 4.73373
284 4TL6 ANP 4.74308
285 1BH2 GSP 4.7619
286 1D2E GDP 4.78589
287 4HDO GNP 4.79042
288 1SQ5 ADP 4.87013
289 2B8T THM 4.93274
290 1D5C GDP 4.93827
291 5O74 GDP 5
292 1O8B ABF 5.02283
293 1KK8 BEF ADP 5.03597
294 1UAD GNP 5.05051
295 1HTW ADP 5.06329
296 3WY9 GDP 5.06912
297 3WYA GDP 5.06912
298 5VHC BEF ADP 5.09978
299 1F5N GNP 5.09978
300 4IDN GNP 5.09978
301 3E4O SIN 5.09978
302 1MO9 FAD 5.09978
303 1MO9 KPC 5.09978
304 2VOS ADP 5.09978
305 4X8O AP5 5.14019
306 3NKV GNP 5.14286
307 1T8U UAP SGN IDS SGN 5.14706
308 3EC1 GDP 5.14905
309 1F9V ADP 5.18732
310 1XP8 AGS 5.19126
311 2CJW GDP 5.20833
312 3DOE GTP 5.20833
313 2GJ8 ALF GDP 5.23256
314 5H4S RAM 5.28169
315 4J0Q GDP 5.31178
316 1YQT ADP 5.32151
317 2BIF SIN 5.32151
318 2BIF ANP 5.32151
319 5AK0 8V1 5.32151
320 3TBK ANP 5.32151
321 4PJ3 ANP 5.32151
322 4MIG G3F 5.32151
323 1KSH GDP 5.37634
324 1JI0 ATP 5.41667
325 1RYH GNP 5.41872
326 4RZ3 ADP 5.42373
327 2W58 ADP 5.44554
328 2B8W ALF 5GP 5.4878
329 4UTG ANP 5.49133
330 5BN3 ADP 5.52885
331 5M7P ADP 5.54324
332 5VGR GDP 5.56845
333 1QF5 GDP 5.56845
334 1QF5 RPL 5.56845
335 5OEC GDP 5.58376
336 1Z0F GDP 5.58659
337 1Z83 AP5 5.61225
338 1X1R GDP 5.61798
339 3AB4 THR 5.61798
340 3FIU POP 5.62249
341 1RRC ADP 5.64784
342 4KFU ACP 5.66038
343 5J1S ATP 5.69106
344 2HT6 GDP 5.74713
345 3IO3 ADP 5.74713
346 1XX6 ADP 5.75916
347 1M2O GNP 5.78947
348 2F3R G5P 5.7971
349 2XT3 ADP 5.81395
350 5KUT GDP 5.82011
351 3CPJ GDP 5.8296
352 3SBD GNP 5.88235
353 1EK0 GNP 5.88235
354 3FYH ADP 5.90062
355 1MH1 GNP 5.91398
356 3WYF GTP 5.93607
357 3M1I GTP 5.93607
358 1G4U GDP 5.97826
359 4NU0 AP5 5.99078
360 2WIC GNP 5.99251
361 3FB4 AP5 6.01852
362 2Z5F A3P 6.04027
363 2OBM ADP 6.05187
364 1R4A GNP 6.06061
365 5LB3 ADP 6.06742
366 1FQK GDP 6.12245
367 1FQK ALF 6.12245
368 1G3M PCQ 6.12245
369 1G3M A3P 6.12245
370 4YDS ATP 6.14035
371 1NF3 GNP 6.15385
372 4M9Q GNP 6.1674
373 5MVR ADP 6.17284
374 2FJU GSP 6.17978
375 4WZA ACP 6.20843
376 4WZA ADP 6.20843
377 1WA5 GTP 6.20843
378 5H7J GCP 6.20843
379 5XC5 GTP 6.25
380 2V2V V12 6.27306
381 1A4R GNH 6.28272
382 1A4R GDP 6.28272
383 4NE2 SH2 6.28743
384 4NE2 ADP 6.28743
385 2Q1W NAD 6.30631
386 2WMO GTP 6.31579
387 5KSP GDP 6.31579
388 1UJ2 ADP 6.34921
389 1UJ2 C5P 6.34921
390 2OZE AGS 6.37584
391 1UKZ ADP 6.40394
392 1H74 ADP 6.41892
393 1H74 ILE 6.41892
394 5W7Q GDP 6.43432
395 3FKQ ATP 6.43432
396 2QN6 GDP 6.45161
397 2GCO GNP 6.46766
398 2GCN GDP 6.46766
399 1Z08 GNP 6.47059
400 4TO8 FLC 6.50685
401 3AQ4 GDP 6.52174
402 2QQ0 ANP 6.52174
403 2QQ0 ADP 6.52174
404 2QQ0 TMP 6.52174
405 2QQ0 THM 6.52174
406 4IEE AGS 6.53061
407 4NON GDP 6.53846
408 2FH5 GTP 6.54206
409 1ZUI SKM 6.54762
410 2AWN ADP 6.56168
411 4JLS 3ZE 6.57895
412 3B5J 12D 6.58436
413 1GXU 2HP 6.59341
414 3T12 GDP ALF 6.61765
415 1O3Y GTP 6.62651
416 1QHG ATP 6.62983
417 4LYA ATP 6.65188
418 3H4S ADP 6.66667
419 1CS4 GSP 6.66667
420 5L3V GDP 6.68896
421 1DAK DPU 6.69643
422 1DAK ADP 6.69643
423 5L3S G 6.71141
424 5L3S GNP 6.71141
425 5G41 AP5 6.72646
426 5LLB 6YZ 6.84411
427 1KO8 6PG 6.85714
428 4GOJ GNP 6.87831
429 5UQW GDP 6.87831
430 5OCG GNP 6.87831
431 4YLG GDP 6.93642
432 3KTA AP5 6.93642
433 5IRC GDP 6.98925
434 2BME GNP 6.98925
435 4D0N GDP 7.02703
436 6BC0 GSP 7.02703
437 5TB5 GDP 7.02703
438 5HPY GDP 7.02703
439 5TAR GDP 7.02703
440 6BCB GSP 7.02703
441 5H7K GDP 7.0529
442 1KMQ GNP 7.06522
443 2ODE ALF GDP 7.0922
444 1Z6T ADP 7.09534
445 4YJ1 ADP 7.09534
446 4KAX GTP 7.10059
447 3RAB GNP 7.10059
448 1U0J ADP 7.11611
449 1CXZ GSP 7.14286
450 4QRH 0O2 7.14286
451 2D7C GTP 7.14286
452 3WXM GTP 7.18085
453 1FZQ GDP 7.18232
454 1QF9 C5P 7.2165
455 1QF9 ALF 7.2165
456 1QF9 ADP 7.2165
457 3FVQ ATP 7.24234
458 4U5X GNP 7.30337
459 4HSE ADP 7.30479
460 1RE0 GDP 7.31707
461 1S9D GDP 7.31707
462 2A5F GTP 7.42857
463 3BOS CDP 7.43802
464 1G7S GDP 7.5388
465 1Z0K GTP 7.55814
466 4K81 GTP 7.60234
467 2A9K GDP 7.62332
468 4KBF AMP 7.67123
469 5GVR LMR 7.69231
470 1AKY AP5 7.72727
471 3REF GDP 7.73196
472 5HR5 ADP 7.76053
473 1LFD GNP 7.78443
474 6D5M GNP 7.78443
475 6D5V GNP 7.78443
476 1CLU DBG 7.83133
477 1NVV GNP 7.83133
478 5FHD ADP ALF 7.85219
479 5FTB ANP 7.85219
480 4CVN ADP 7.8534
481 2C77 GNP 7.90123
482 2C78 GNP 7.90123
483 4ITR GDP 7.91139
484 5UIV ADP 7.92952
485 1ZD9 GDP 7.98226
486 3CNL GNP 8.01527
487 3N5C GDP 8.02469
488 3PCR GTP 8.02469
489 2VB6 ADP BEF 8.05369
490 4R2I ANP 8.09524
491 4YC7 GNP 8.13648
492 1HE1 GDP 8.14815
493 5L3W GDP 8.16993
494 4Q1A UDP 8.21429
495 4Q1A 2XZ 8.21429
496 5E95 GDP 8.24742
497 4ZI2 GNP 8.27068
498 4HUT ATP 8.37696
499 1WQ1 AF3 8.38323
500 1WQ1 GDP 8.38323
501 1R0X ATP 8.39161
502 2HF9 GSP 8.40708
503 4C4P GNP 8.41121
504 2GK6 ADP 8.42572
505 1I4D GDP 8.48214
506 5H67 ATP 8.54271
507 5E5U MLI 8.54271
508 4V03 ADP 8.56031
509 3DDC GNP 8.58896
510 1T5C ADP 8.59599
511 4WZ6 ATP 8.62069
512 5DI3 GNP 8.64865
513 2ZEJ GDP 8.69565
514 5Z2M GTP 8.69565
515 1DS6 GDP 8.88889
516 2OG2 MLI 8.91365
517 1Z2A GDP 8.92857
518 3E5H GNP 8.98876
519 5BQ5 ADP BEF 8.99471
520 2W83 GTP 9.09091
521 3RLF ANP 9.12162
522 1W7J ADP BEF 9.27152
523 3VX3 ADP 9.27419
524 4AUT FAD 9.31264
525 4P8K 38C 9.31264
526 4P8K FAD 9.31264
527 1L2T ATP 9.3617
528 2RCN GDP 9.49721
529 2J59 GTP 9.52381
530 1F6B GDP 9.59596
531 6C90 ADP 9.61539
532 3IUY AMP 9.64912
533 1ZC3 GNP 9.73451
534 2PS1 ORO 9.73451
535 1GUA GNP 9.87654
536 1TU3 GNP 9.94152
537 2A5J GDP 9.94764
538 3GJ3 GDP 9.95475
539 3GJ7 GDP 9.95475
540 3GJ4 GDP 9.95475
541 3GJ0 GDP 9.95475
542 3GJ5 GDP 9.95475
543 1R2Q GNP 10
544 1RJ9 GCP 10
545 1FNN ADP 10.0257
546 3MJH GTP 10.119
547 3NHB ADP 10.1307
548 1F2U ATP 10.1351
549 3Q72 GNP 10.241
550 3BC1 GNP 10.2564
551 2PZM UDP 10.303
552 2PZM NAD 10.303
553 4R98 GNH 10.3321
554 5UWQ GNP 10.4895
555 5UWU GNP 10.4895
556 5UWO GNP 10.4895
557 5UWS GNP 10.4895
558 5UWR GNP 10.4895
559 5UWT GNP 10.4895
560 5UWI GNP 10.4895
561 5UWJ GNP 10.4895
562 5UWW GNP 10.4895
563 5DIF GNP 10.4895
564 5DHF GNP 10.4895
565 5DI9 GNP 10.4895
566 3T5G GDP 10.4972
567 1NRJ GTP 10.5505
568 2G77 AF3 10.6061
569 2G77 GDP 10.6061
570 6BSX E7S 10.6742
571 6BSX GDP 10.6742
572 4HAT GNP 10.7143
573 4XOI GTP 10.7407
574 1OW3 GDP 10.7438
575 2ZX2 RAM 10.7692
576 3W5J GDP 10.7843
577 2XAU ADP 10.8647
578 3GJ8 GDP 10.8696
579 2PZE ATP 10.917
580 2YOH WMJ 10.9524
581 2CBZ ATP 10.9705
582 5LTJ BEF 11.0865
583 5LTJ ADP 11.0865
584 2NGR GDP 11.1111
585 3KUD GDP 11.1111
586 1G16 GDP 11.1765
587 5O2T GSP 11.2299
588 6B8B ADP 11.245
589 5XDR ADP 11.3082
590 5IRR GSP 11.3636
591 2VOH CIT 11.465
592 3CH5 GDP 11.5385
593 2F5X ASP 11.5385
594 1MR3 G3D 11.6022
595 3WYG GTP 11.8421
596 6BCA GSP 11.9205
597 3A4M ADP 11.9231
598 5W76 GDP 11.9481
599 6FAA ADP 11.9734
600 2KIN ADP 12
601 3V2U ATP 12.1951
602 4B47 GDP 12.3967
603 5SZH GNP 12.4183
604 6D5G GNP 12.5749
605 6D5E GNP 12.5749
606 6BVJ GNP 12.5749
607 6BVK GNP 12.5749
608 6D55 GNP 12.5749
609 6D59 GNP 12.5749
610 6D5J GNP 12.5749
611 6D56 GNP 12.5749
612 6BVM GNP 12.5749
613 6D5L GNP 12.5749
614 6BVI GNP 12.5749
615 6D5H GNP 12.5749
616 6BVL GNP 12.5749
617 5FG3 GDP 12.6386
618 1M7G AV2 12.7962
619 1M7G ADP 12.7962
620 1M7G ADX 12.7962
621 1GRN GDP 12.8079
622 1GRN AF3 12.8079
623 2W2X GSP 12.9032
624 4D0G GTP 13.0435
625 3B7G ANP 13.0435
626 1TX4 ALF GDP 13.1313
627 2J0V GDP 13.2075
628 1Z06 GNP 13.2275
629 6DEF GCP 13.2992
630 3E70 GDP 13.4146
631 5WDR GNP 13.4503
632 3LXR GDP 14.0625
633 1S8F GDP 14.1243
634 6G14 G4P 14.2857
635 1FQJ GDP 14.2857
636 1FQJ ALF 14.2857
637 2BCG GDP 14.5631
638 4U00 ADP 14.7541
639 1QHH ATP 14.7826
640 4HI0 GDP 14.9606
641 3A1S GDP 15.1163
642 3RWO GDP 15.1351
643 4V0K GDP 15.3846
644 2WJG GDP 15.4255
645 1E96 GTP 15.7635
646 3CX8 GSP 15.7635
647 3ZIA ADP 15.873
648 3ZIA ATP 15.873
649 1YZQ GNP 15.8824
650 2CDN ADP 15.9204
651 1Z0A GDP 16.092
652 1YZN GNP 16.2162
653 2C5L GTP 16.2393
654 3U6B GDP 16.2437
655 4P3Y GDP 16.2437
656 5JBQ GDP 16.2437
657 4G5G GDP 16.2437
658 3U6K GDP 16.2437
659 4PC3 GDP 16.2437
660 1D8T GDP 16.285
661 2BVN GNP 16.285
662 2FFQ GSP 16.3743
663 4DID GDP 16.4474
664 1KY3 GDP 17.033
665 2QZ4 ADP 17.1756
666 3RC3 ANP 17.2949
667 4XZ3 ACP 17.3913
668 1XEX ATP 17.4419
669 2WJH FLC 17.4699
670 2WJH GDP 17.4699
671 1JJV ATP 17.4757
672 3BFV ADP 17.7122
673 2PL3 ADP 17.7966
674 4XSH GSP 17.8082
675 4BQS K2Q 18.1818
676 4BQS ADP 18.1818
677 5JCZ GDP 18.8917
678 4E03 ADP 18.932
679 6FA4 GNP 19.0751
680 2HCJ GDP 19.1045
681 4PX9 ADP 19.1781
682 2UZI GTP 19.2982
683 4NCN GTP 19.5122
684 2CK3 ANP 20
685 2CK3 ADP 20
686 2QTV GNP 20.4082
687 5WLB GNP 20.5882
688 3ZS9 ADP ALF 21.0526
689 2V7Q ATP 21.2121
690 2V7Q ADP 21.2121
691 5LEF GTP 21.2121
692 2EW1 GNP 21.8905
693 6CRK GDP 22.5352
694 1GP2 GDP 22.5352
695 4LHW GNP 24.1379
696 3QBT GNP 24.1379
697 3TNF GNP 24.1379
698 4P83 U5P 24.1758
699 4TMZ GSP 25.5072
700 4HDQ GNP 26.9231
701 5KDO GDP 27.027
702 5UWH GNP 27.2727
703 4OI4 ATP 28.6957
704 1GOT GDP 28.7671
705 5UWP GNP 36.8421
706 1J2J GTP 37.7778
707 6CIT GNP 38.0952
708 5UPK GNP 41.6667
709 5YT0 GDP 42.8571
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