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Receptor
PDB id Resolution Class Description Source Keywords
2JC9 1.5 Å EC: 3.1.3.5 CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC 5'-NUCLEOTIDASE II IN COMPLEX WITH ADENOSINE HOMO SAPIENS CYTOSOLIC 5-PRIME NUCLEOTIDASE II GMP-IMP SPECIFIC NUCLEOTIDASE CN-II NT5C2 HYDROLASE POLYMORPHISM CYTOSOLIC PURINE 5-PRIME NUCLEOTIDASE ALLOSTERIC ENZYME HIGH KM 5-PRIME NUCLEOTIDASE
Ref.: CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC 5'-NUCLEOTIDASE II: INSIGHTS INTO ALLOSTERIC REGULATION AND SUBSTRATE RECOGNITION J.BIOL.CHEM. V. 282 17828 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADN A:1497;
A:1498;
Valid;
Valid;
none;
none;
submit data
267.241 C10 H13 N5 O4 c1nc(...
GOL A:1489;
A:1490;
Invalid;
Invalid;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
MG A:1491;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
SO4 A:1492;
A:1493;
A:1494;
A:1495;
A:1496;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2JC9 1.5 Å EC: 3.1.3.5 CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC 5'-NUCLEOTIDASE II IN COMPLEX WITH ADENOSINE HOMO SAPIENS CYTOSOLIC 5-PRIME NUCLEOTIDASE II GMP-IMP SPECIFIC NUCLEOTIDASE CN-II NT5C2 HYDROLASE POLYMORPHISM CYTOSOLIC PURINE 5-PRIME NUCLEOTIDASE ALLOSTERIC ENZYME HIGH KM 5-PRIME NUCLEOTIDASE
Ref.: CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC 5'-NUCLEOTIDASE II: INSIGHTS INTO ALLOSTERIC REGULATION AND SUBSTRATE RECOGNITION J.BIOL.CHEM. V. 282 17828 2007
Members (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 10 families.
1 2JC9 - ADN C10 H13 N5 O4 c1nc(c2c(n....
2 2XJF - DG2 C3 H8 O10 P2 C([C@H](C(....
3 2XJE - U5P C9 H13 N2 O9 P C1=CN(C(=O....
4 2XCV - IMP C10 H13 N4 O8 P c1nc2c(n1[....
5 2XJD - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
6 6DE2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
7 2XCW - IMP C10 H13 N4 O8 P c1nc2c(n1[....
8 2XJC - B4P C20 H28 N10 O19 P4 c1nc(c2c(n....
9 6DDZ - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
10 2XJB - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
70% Homology Family (12)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 2JC9 - ADN C10 H13 N5 O4 c1nc(c2c(n....
2 2XJF - DG2 C3 H8 O10 P2 C([C@H](C(....
3 2XJE - U5P C9 H13 N2 O9 P C1=CN(C(=O....
4 2XCV - IMP C10 H13 N4 O8 P c1nc2c(n1[....
5 2XJD - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
6 6DE2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
7 2XCW - IMP C10 H13 N4 O8 P c1nc2c(n1[....
8 2XJC - B4P C20 H28 N10 O19 P4 c1nc(c2c(n....
9 6DDZ - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
10 2XJB - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
11 5OPK - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
12 5OPM - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
50% Homology Family (12)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 2JC9 - ADN C10 H13 N5 O4 c1nc(c2c(n....
2 2XJF - DG2 C3 H8 O10 P2 C([C@H](C(....
3 2XJE - U5P C9 H13 N2 O9 P C1=CN(C(=O....
4 2XCV - IMP C10 H13 N4 O8 P c1nc2c(n1[....
5 2XJD - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
6 6DE2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
7 2XCW - IMP C10 H13 N4 O8 P c1nc2c(n1[....
8 2XJC - B4P C20 H28 N10 O19 P4 c1nc(c2c(n....
9 6DDZ - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
10 2XJB - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
11 5OPK - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
12 5OPM - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADN; Similar ligands found: 305
No: Ligand ECFP6 Tc MDL keys Tc
1 RAB 1 1
2 ADN 1 1
3 XYA 1 1
4 5N5 0.811321 0.967742
5 5CD 0.796296 0.920635
6 A4D 0.796296 0.967742
7 MTA 0.758621 0.878788
8 EP4 0.754386 0.852941
9 M2T 0.741379 0.828571
10 DTA 0.741379 0.865672
11 AMP 0.709677 0.842857
12 A 0.709677 0.842857
13 3DH 0.704918 0.878788
14 ZAS 0.68254 0.84058
15 LMS 0.68254 0.7375
16 5AD 0.672727 0.854839
17 SRA 0.671875 0.797297
18 6RE 0.671875 0.830986
19 DSH 0.661538 0.842857
20 AOC 0.661538 0.907692
21 7D7 0.660714 0.875
22 ABM 0.651515 0.819444
23 A2D 0.651515 0.84507
24 J7C 0.651515 0.842857
25 A3N 0.651515 0.923077
26 ADP 0.647059 0.84507
27 S4M 0.641791 0.766234
28 GJV 0.641791 0.819444
29 3AM 0.640625 0.828571
30 AN2 0.637681 0.833333
31 BA3 0.632353 0.84507
32 A12 0.632353 0.810811
33 AP2 0.632353 0.810811
34 MAO 0.632353 0.75641
35 Y3J 0.627119 0.828125
36 5AS 0.623188 0.714286
37 AP5 0.623188 0.84507
38 B4P 0.623188 0.84507
39 ATP 0.619718 0.84507
40 HEJ 0.619718 0.84507
41 5X8 0.619718 0.865672
42 AT4 0.614286 0.810811
43 A7D 0.614286 0.909091
44 SON 0.614286 0.786667
45 5FA 0.611111 0.84507
46 AQP 0.611111 0.84507
47 APC 0.611111 0.810811
48 26A 0.606557 0.893939
49 2FA 0.606557 0.924242
50 ADX 0.605634 0.759494
51 AU1 0.605634 0.821918
52 CA0 0.605634 0.821918
53 MHZ 0.605634 0.75641
54 M33 0.605634 0.833333
55 AGS 0.60274 0.8
56 AD9 0.60274 0.821918
57 SAP 0.60274 0.8
58 2AM 0.6 0.842857
59 ACP 0.597222 0.821918
60 SFG 0.597222 0.850746
61 50T 0.597222 0.833333
62 MTP 0.590164 0.852941
63 APR 0.589041 0.84507
64 PRX 0.589041 0.797297
65 AR6 0.589041 0.84507
66 A3G 0.588235 0.938462
67 ACQ 0.586667 0.821918
68 T99 0.586667 0.810811
69 TAT 0.586667 0.810811
70 A3P 0.585714 0.816901
71 SA8 0.581081 0.794521
72 RBY 0.581081 0.810811
73 A5D 0.581081 0.865672
74 ADP PO3 0.581081 0.842857
75 ADV 0.581081 0.810811
76 6MD 0.580645 0.952381
77 1DA 0.580645 1
78 ADQ 0.575 0.847222
79 OVE 0.573529 0.808219
80 SAH 0.573333 0.84058
81 G5A 0.573333 0.714286
82 SAI 0.573333 0.828571
83 A22 0.56962 0.833333
84 ANP 0.565789 0.821918
85 GAP 0.565789 0.821918
86 SAM 0.565789 0.773333
87 NEC 0.565217 0.876923
88 3AD 0.564516 0.951613
89 6YZ 0.564103 0.821918
90 25A 0.5625 0.819444
91 7D5 0.560606 0.780822
92 5AL 0.558442 0.808219
93 AAT 0.558442 0.819444
94 EEM 0.558442 0.773333
95 ADP ALF 0.551282 0.776316
96 ATF 0.551282 0.810811
97 A5A 0.551282 0.719512
98 ALF ADP 0.551282 0.776316
99 CC5 0.55 0.935484
100 A3S 0.547945 0.953125
101 SSA 0.544304 0.73494
102 S7M 0.544304 0.773333
103 ADP VO4 0.544304 0.808219
104 VO4 ADP 0.544304 0.808219
105 SRP 0.544304 0.810811
106 SMM 0.544304 0.74359
107 QQX 0.544118 0.756757
108 S8M 0.54321 0.805556
109 ADP BMA 0.542169 0.847222
110 A2P 0.541667 0.802817
111 3L1 0.539683 0.907692
112 3D1 0.539683 0.907692
113 PAP 0.539474 0.830986
114 VMS 0.5375 0.702381
115 52H 0.5375 0.694118
116 54H 0.5375 0.702381
117 LSS 0.536585 0.678161
118 QQY 0.536232 0.767123
119 ACK 0.536232 0.811594
120 A3T 0.533333 0.968254
121 53H 0.530864 0.694118
122 5CA 0.530864 0.73494
123 TSB 0.530864 0.731707
124 8X1 0.530864 0.689655
125 MAP 0.530864 0.8
126 DAL AMP 0.530864 0.808219
127 OOB 0.52439 0.808219
128 9ZA 0.52439 0.766234
129 8QN 0.52439 0.808219
130 5SV 0.52439 0.75641
131 9ZD 0.52439 0.766234
132 GEK 0.52439 0.805556
133 OAD 0.52381 0.821918
134 9X8 0.52381 0.8
135 25L 0.523256 0.833333
136 PPS 0.518987 0.7375
137 DSZ 0.518072 0.714286
138 AMO 0.518072 0.810811
139 A1R 0.518072 0.813333
140 A3R 0.518072 0.813333
141 0UM 0.518072 0.808219
142 4AD 0.518072 0.8
143 PAJ 0.518072 0.792208
144 NSS 0.518072 0.714286
145 A A 0.517647 0.819444
146 6CR 0.515152 0.910448
147 SP1 0.514286 0.77027
148 RP1 0.514286 0.77027
149 2VA 0.513158 0.938462
150 DLL 0.511905 0.808219
151 AHX 0.511905 0.802632
152 00A 0.511905 0.766234
153 62X 0.511905 0.74359
154 NVA LMS 0.511905 0.670455
155 3OD 0.511628 0.821918
156 PTJ 0.511628 0.75641
157 ME8 0.511628 0.728395
158 7D3 0.506849 0.783784
159 V3L 0.506329 0.819444
160 A6D 0.505882 0.763158
161 LEU LMS 0.505882 0.670455
162 K15 0.505882 0.763158
163 3UK 0.505882 0.797297
164 GSU 0.5 0.694118
165 B5V 0.5 0.786667
166 P5A 0.5 0.681818
167 KAA 0.5 0.689655
168 NVA 2AD 0.5 0.884058
169 PR8 0.5 0.759494
170 CMP 0.5 0.826087
171 LAD 0.5 0.769231
172 ATR 0.5 0.816901
173 5F1 0.5 0.80597
174 2BA 0.5 0.814286
175 WAQ 0.5 0.766234
176 AD3 0.5 1
177 ATP A A A 0.494382 0.830986
178 9K8 0.494253 0.670455
179 JB6 0.494253 0.766234
180 1ZZ 0.494253 0.728395
181 FYA 0.494253 0.808219
182 SXZ 0.494253 0.773333
183 TXA 0.494253 0.810811
184 BIS 0.494253 0.789474
185 NB8 0.494253 0.779221
186 SO8 0.493671 0.924242
187 VRT 0.493671 0.897059
188 IVH 0.493333 0.835616
189 KB1 0.488636 0.783784
190 MYR AMP 0.488636 0.728395
191 2A5 0.487179 0.797297
192 NOC 0.484375 0.903226
193 4UV 0.483516 0.776316
194 9SN 0.483146 0.75641
195 A2R 0.481928 0.833333
196 7D4 0.480519 0.783784
197 FA5 0.477778 0.786667
198 YAP 0.477778 0.776316
199 B5Y 0.477778 0.776316
200 B5M 0.477778 0.776316
201 8PZ 0.477778 0.714286
202 D3Y 0.47619 0.924242
203 AR6 AR6 0.473118 0.819444
204 AFH 0.473118 0.792208
205 YSA 0.472527 0.694118
206 XAH 0.472527 0.75
207 EKK 0.469697 0.923077
208 TBN 0.46875 0.983607
209 3BH 0.46875 0.953125
210 AMP DBH 0.467391 0.821918
211 TYR AMP 0.467391 0.776316
212 101 0.465753 0.780822
213 LAQ 0.463158 0.728395
214 TO1 0.462687 0.952381
215 G3A 0.462366 0.779221
216 7C5 0.462366 0.819444
217 UPA 0.459184 0.813333
218 LPA AMP 0.458333 0.728395
219 G5P 0.457447 0.779221
220 7MD 0.457447 0.772152
221 ARG AMP 0.457447 0.740741
222 4UU 0.457447 0.776316
223 GA7 0.457447 0.835616
224 A A A 0.454545 0.808219
225 EKH 0.454545 0.923077
226 5ID 0.454545 0.923077
227 TAD 0.452632 0.769231
228 4YB 0.452632 0.678161
229 GTA 0.452632 0.75
230 KH3 0.452632 0.776316
231 DQV 0.452632 0.833333
232 3NZ 0.449438 0.884058
233 WSA 0.44898 0.702381
234 OMR 0.44898 0.740741
235 TYM 0.44898 0.786667
236 AHZ 0.447917 0.728395
237 FTU 0.447761 0.923077
238 139 0.445545 0.782051
239 YLP 0.443299 0.731707
240 48N 0.443299 0.779221
241 AFX 0.441176 0.768116
242 ARJ 0.441176 0.857143
243 AV2 0.440476 0.77027
244 DA 0.44 0.756757
245 D5M 0.44 0.756757
246 5J9 0.43956 0.773333
247 UP5 0.438776 0.8
248 NAI 0.438776 0.789474
249 NXX 0.438776 0.810811
250 NAX 0.438776 0.759494
251 6V0 0.438776 0.779221
252 4UW 0.438776 0.746835
253 TXD 0.438776 0.789474
254 DND 0.438776 0.810811
255 NA7 0.438202 0.810811
256 PO4 PO4 A A A A PO4 0.438202 0.802817
257 MZR 0.4375 0.859375
258 V1N 0.43617 0.819444
259 HO4 0.434783 0.952381
260 TXE 0.434343 0.789474
261 649 0.434343 0.662921
262 AF3 ADP 3PG 0.434343 0.746835
263 IMO 0.434211 0.777778
264 3AT 0.433735 0.819444
265 G A A A 0.432692 0.779221
266 8Q2 0.43 0.689655
267 F0P 0.43 0.794521
268 AP0 0.43 0.779221
269 7MC 0.43 0.753086
270 YLC 0.43 0.75
271 YLB 0.43 0.731707
272 4TC 0.43 0.779221
273 SGV 0.428571 0.967742
274 BS5 0.427184 0.674157
275 A4P 0.425743 0.73494
276 IOT 0.421569 0.722892
277 DAT 0.419753 0.76
278 COD 0.419048 0.72619
279 T5A 0.417476 0.731707
280 ADJ 0.417476 0.740741
281 YLA 0.417476 0.731707
282 AS 0.415584 0.717949
283 J1D 0.415094 0.625
284 0XU 0.414634 0.823529
285 CNA 0.413462 0.810811
286 AYB 0.413462 0.722892
287 103 0.413333 0.716216
288 A U 0.411765 0.8
289 80F 0.411215 0.731707
290 GMP 0.410959 0.882353
291 EO7 0.410256 0.702381
292 F2R 0.409524 0.753086
293 GGZ 0.409091 0.7125
294 U A 0.407407 0.766234
295 ITT 0.407407 0.791667
296 A G 0.40566 0.766234
297 BTX 0.40566 0.710843
298 4TA 0.40566 0.719512
299 NAD 0.40566 0.808219
300 AMP NAD 0.40566 0.808219
301 SFB 0.401961 0.709302
302 DZD 0.401869 0.769231
303 U A G G 0.401869 0.766234
304 BT5 0.401869 0.702381
305 DTP 0.4 0.76
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2JC9; Ligand: ADN; Similar sites found with APoc: 134
This union binding pocket(no: 1) in the query (biounit: 2jc9.bio1) has 9 residues
No: Leader PDB Ligand Sequence Similarity
1 1Q9I FAD 1.44144
2 1Q9I TEO 1.44144
3 3GDN MXN 1.53551
4 4Y9J UCC 1.62162
5 4LY9 S6P 1.8018
6 4ZW3 4S9 1.8018
7 2WPX ACO 1.8018
8 1MUU GDX 1.83486
9 1U2Z SAH 1.84758
10 3V49 PK0 1.8797
11 5MWY YNU 1.98198
12 6H21 UD1 2.02899
13 2OBF SAH 2.07612
14 5GS9 ARG 2.07715
15 3TGE TGE 2.14724
16 4XAQ 40F 2.38569
17 3SQP 3J8 2.51046
18 2B56 U5P 2.5641
19 5AZC PGT 2.66667
20 5OHJ 9VE 2.85036
21 1D4D SIN 3.06306
22 6GEH FAD 3.125
23 6F70 GSH 3.1746
24 4E5N NAD 3.33333
25 2GWH PCI 3.3557
26 3GWT 066 3.39943
27 1E7S NAP 3.42679
28 2XCG XCG 3.46154
29 6DIO CIT 3.4965
30 4B5P ACO 3.5
31 2B4D COA 3.50877
32 5LIA 6XN 3.6036
33 5CHR 4NC 3.64964
34 2EVL GAL SPH EIC 3.82775
35 4QJL COA 3.82979
36 3T6E UQ9 3.87597
37 1WUB OTP 3.93258
38 1GHE ACO 3.9548
39 2P4Y C03 3.97112
40 4XPQ FUL 4.14414
41 2OBD PCW 4.20168
42 3F8K COA 4.375
43 3G4G D71 4.51306
44 5K53 STE 4.58015
45 2ZIF SAM 4.7138
46 1P1M MET 4.92611
47 5ECP MET 4.93274
48 5ECP JAA 4.93274
49 5ECP ATP 4.93274
50 3G58 988 4.98688
51 5KBZ 3B2 5.03979
52 4M52 FAD 5.15021
53 2C9E PID 5.19878
54 5J6D 6H5 5.21173
55 4C4A SAH 5.40541
56 3T50 FMN 5.46875
57 3SE5 ANP 5.4878
58 5KZV HCD 5.51181
59 1XMU ROF 5.52764
60 1XM4 PIL 5.52764
61 1XMY ROL 5.52764
62 1BWO LPC 5.55556
63 1S17 GNR 5.55556
64 6BSX GDP 5.61798
65 4DR9 BB2 5.72917
66 1TO9 HMH 5.76923
67 5X0J AMP 5.78512
68 3PVT 3HC 5.79151
69 3E7O 35F 5.83333
70 4JBI NDP 5.94595
71 1G27 BB1 5.95238
72 3A4T SFG 6.20438
73 4V3I ASP LEU THR ARG PRO 6.22568
74 5B4B LP5 6.45161
75 3GKJ HC3 6.46552
76 6EOZ AKG 6.49351
77 6EOZ 58K 6.49351
78 3QMK SGN IDS SGN IDS 6.54206
79 5C2H 4XU 6.62983
80 3DRG ARG PRO PRO GLY PHE SER PRO PHE ALA 6.66667
81 5YJF 8WO 6.69014
82 5YJF SAH 6.69014
83 5YJI SAH 6.69014
84 5YJI 8WO 6.69014
85 5TO8 7FM 6.73759
86 4QJK COA 6.80851
87 5WL1 D3D 7.07071
88 5WL1 CUY 7.07071
89 5UR6 8KM 7.18232
90 1EYQ NAR 7.20721
91 5OM2 DXT 7.31707
92 3HQP FDP 7.41483
93 1CX4 CMP 7.54098
94 3ZLR X0B 7.59494
95 2BCG GER 7.76699
96 2XXP DSL 7.78894
97 2HJ3 FAD 8
98 2D5Z L35 8.21918
99 3LN0 52B 8.28829
100 4QC6 30N 8.37989
101 5TBM 79A 8.54701
102 5MTE BB2 8.75912
103 4MZQ 1VU 9.02778
104 4RYV ZEA 9.03226
105 3E9I XAH 9.33063
106 2C5L GTP 9.40171
107 3SFI 3SF 9.74576
108 4OAS 2SW 10.4167
109 2H88 TEO 11.1111
110 3O0Q TTP 11.1712
111 3O0Q GDP 11.1712
112 3O0Q ADN 11.1712
113 2VBQ BSJ 11.5152
114 5V3Y 5V8 11.5385
115 4WN5 MVC 12.1739
116 6FS0 E4W 12.5786
117 4WGF HX2 12.6829
118 5THZ SAH 12.8395
119 1Y0G 8PP 13.089
120 2EW5 Y12 13.2597
121 3HUJ AGH 14.0845
122 4YSX E23 14.3617
123 4IBF 1D5 14.7287
124 2AZ5 307 14.8649
125 2WDQ TEO 15.6522
126 4DOL PLM 16.129
127 3QUZ QUV 16.1616
128 1RC0 KT5 16.2679
129 4QVX 3CQ 17.9641
130 4R57 ACO 23.8636
131 5IXK 6EW 24.1228
132 3KXC PLM 25.3165
133 3L9R L9R 25.5102
134 4OGQ 2WA 34.4828
Pocket No.: 2; Query (leader) PDB : 2JC9; Ligand: ADN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2jc9.bio1) has 9 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 2JC9; Ligand: ADN; Similar sites found with APoc: 184
This union binding pocket(no: 3) in the query (biounit: 2jc9.bio1) has 14 residues
No: Leader PDB Ligand Sequence Similarity
1 4WG0 CHD None
2 3JRX S1A 0.900901
3 3EDF ACX 1.08108
4 3EDF CE6 1.08108
5 5DB3 58Q 1.22699
6 2ZRU FMN 1.3587
7 2RH1 CLR 1.4
8 4IPE ANP 1.44144
9 1N20 3AG 1.45719
10 4QGE 35O 1.50094
11 5X93 K87 1.62162
12 1ZED PNP 1.65289
13 3OTH CLJ 1.69903
14 2XFH CL6 1.70316
15 2YOO K2B 1.7199
16 1UDY FAD 1.76768
17 6CGN DA 1.8018
18 3NRR D16 1.94175
19 3NRR NAP 1.94175
20 2AX9 BHM 1.95312
21 1ZDU P3A 2.04082
22 5OLK DTP 2.09302
23 2VL8 UDP 2.1978
24 2VL8 CTS 2.1978
25 4YBN FAD 2.23214
26 3IHG FAD 2.24299
27 3HP9 CF1 2.28216
28 4QEK GLC 2.32558
29 1GNI OLA 2.34234
30 3ETG GTP 2.39521
31 2PX6 DH9 2.53165
32 5O42 NAD 2.55474
33 5O42 BGC 2.55474
34 5O42 9JW 2.55474
35 5TWO 7MV 2.57353
36 6C1R EFD 2.60664
37 2HHP FLC 2.64151
38 2TPS TPS 2.64317
39 1NP7 FAD 2.65849
40 1ZPD CIT 2.7027
41 4GU5 FAD 2.7027
42 2E3N 6CM 2.7451
43 5A4W QCT 2.83019
44 5N5U 7N8 2.86624
45 3MBG FAD 2.8777
46 5LX9 OLB 2.9316
47 2UW1 GVM 2.95858
48 6HH6 A3R 3.01318
49 2YB9 HA0 3.06306
50 1W96 S1A 3.06859
51 3PG7 PTY 3.125
52 1K7L 544 3.125
53 4A0S NAP 3.13199
54 3SP6 IL2 3.15789
55 2GBB CIT 3.20513
56 5IKH 6BW 3.27273
57 1R6N 434 3.31754
58 1T27 PCW 3.32103
59 2A1L PCW 3.33333
60 4XU6 TDA 3.33333
61 2NPA MMB 3.33333
62 4E90 7RG 3.34347
63 2J1P GRG 3.41297
64 4UCC ZKW 3.43348
65 3RGA ILD 3.53357
66 5IM3 DTP 3.6036
67 6C7D EOJ 3.80117
68 1SR7 MOF 3.861
69 2Q2Y ADP 3.96396
70 2Q2Y MKR 3.96396
71 4F0B GDS 4.01786
72 4UDB CV7 4.04412
73 4ZB8 GDS 4.05405
74 4RHP PEF 4.25532
75 1U72 MTX 4.30108
76 1U72 NDP 4.30108
77 3P5P A3C 4.32432
78 2A3I C0R 4.34783
79 5XNA SHV 4.34783
80 5AM1 I5T 4.37158
81 2BVL GLC 4.41989
82 2BVL UDP 4.41989
83 5N9T 8QQ 4.48179
84 4ZB6 GDS 4.4843
85 2E2R 2OH 4.5082
86 3V66 D3A 4.70588
87 4ELG 52I 4.81928
88 4ELG 52J 4.81928
89 1KDO C 4.84582
90 4V24 GYR 5.04504
91 2ZCQ B65 5.11945
92 3WCA FPS 5.20548
93 3N7S 3N7 5.20833
94 3EE4 MYR 5.26316
95 5G57 6M5 5.27778
96 1NHZ 486 5.35714
97 3LLI FAD 5.36398
98 1T8U UAP SGN IDS SGN 5.40541
99 5DF1 58X 5.43478
100 5DF1 NAP 5.43478
101 3STD MQ0 5.45455
102 5EHR 5OD 5.51331
103 4KIB SAH 5.60224
104 3ITJ CIT 5.6213
105 3VVY ET 5.6701
106 5UQK U2F 5.76577
107 4LSJ LSJ 5.81395
108 1M2Z DEX 5.83658
109 1M2Z BOG 5.83658
110 5EY0 GTP 5.83942
111 4P6X HCY 5.88235
112 4QWT ACD 5.94595
113 3GN8 DEX 6.0241
114 4D52 GXL 6.03175
115 5UFS 1TA 6.04839
116 3AI3 SOE 6.08365
117 5UBG PRT 6.19469
118 4RW3 TDA 6.29139
119 1XON PIL 6.30372
120 4BNU 9KQ 6.3197
121 5AAV GW5 6.34921
122 1I0B PEL 6.62651
123 5C2H 4PX 6.62983
124 1ZGA HMK 6.72269
125 5F1R 42O 6.75105
126 4WP9 ZDA 6.77966
127 5UGW GSH 6.85714
128 1Q7E MET 7.00935
129 3DHV DAL AMP 7.02703
130 1YUC EPH 7.02703
131 2BIF BOG 7.03625
132 1XVB 3BR 7.05882
133 3KMZ EQO 7.14286
134 3ET3 ET1 7.19178
135 4GFD 0YB 7.31707
136 4ZGM 32M 7.37705
137 3OJI PYV 7.40741
138 2BJ4 OHT 7.53968
139 4OMJ 2TX 7.55396
140 4H07 IPH 7.79221
141 1Z83 AP5 8.16327
142 4E2J MOF 8.4
143 1DKF BMS 8.58369
144 4M73 M72 8.60534
145 4M73 SAH 8.60534
146 1RDT L79 8.67769
147 3D04 SAK 8.80503
148 3AQT RCO 9.38776
149 5W7B MYR 9.95261
150 3O01 DXC 10.0649
151 3D78 NBB 10.084
152 3K87 FAD 10.2703
153 3ET1 ET1 10.3093
154 2QHD DAO 10.6557
155 1HBK COA 11.236
156 6CS8 F9Y 11.5512
157 5V4R MGT 12.3457
158 5OYH T99 12.4352
159 5M36 9SZ 13.1579
160 4DRJ RAP 13.2653
161 5LXT GDP 13.4831
162 2ALG DAO 14.1304
163 2ALG HP6 14.1304
164 5V03 658 15.4362
165 3RUG DB6 16.1616
166 5NI5 8YB 19.0972
167 5W97 CHD 19.5652
168 5Z84 CHD 19.5652
169 5ZCO CHD 19.5652
170 2DYS PSC 19.5652
171 5ZCO PSC 19.5652
172 6ESN BWE 20.5993
173 5NTW 98N 20.6226
174 2Y69 CHD 20.7101
175 5APK 76E 20.7547
176 1NU4 MLA 21.6495
177 3KO0 TFP 21.7822
178 5GPG RAP 23.0769
179 2BW7 ECS 23.2877
180 2BW7 APC 23.2877
181 5M37 9SZ 25
182 3L9R L9Q 25.5102
183 4OGQ 1O2 34.4828
184 4OGQ 7PH 34.4828
Pocket No.: 4; Query (leader) PDB : 2JC9; Ligand: ADN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 2jc9.bio1) has 14 residues
No: Leader PDB Ligand Sequence Similarity
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