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Receptor
PDB id Resolution Class Description Source Keywords
2IXE 2 Å EC: 3.-.-.- CRYSTAL STRUCTURE OF THE ATPASE DOMAIN OF TAP1 WITH ATP (D645N MUTANT) RATTUS NORVEGICUS ABC ATPASE HYDROLASE
Ref.: DISTINCT STRUCTURAL AND FUNCTIONAL PROPERTIES OF TH SITES IN AN ASYMMETRIC ABC TRANSPORTER. MOL.CELL V. 24 51 2001
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ATP A:1;
D:1;
Valid;
Valid;
none;
none;
submit data
507.181 C10 H16 N5 O13 P3 c1nc(...
MG A:2;
D:2;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
PO4 A:3;
Invalid;
none;
submit data
94.971 O4 P [O-]P...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2IXE 2 Å EC: 3.-.-.- CRYSTAL STRUCTURE OF THE ATPASE DOMAIN OF TAP1 WITH ATP (D645N MUTANT) RATTUS NORVEGICUS ABC ATPASE HYDROLASE
Ref.: DISTINCT STRUCTURAL AND FUNCTIONAL PROPERTIES OF TH SITES IN AN ASYMMETRIC ABC TRANSPORTER. MOL.CELL V. 24 51 2001
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 253 families.
1 2IXE - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 2IXF - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 175 families.
1 1JJ7 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 2IXE - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
3 2IXF - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
50% Homology Family (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 149 families.
1 2FFB - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 3B5J Kd = 1.2 uM 12D C16 H16 N8 O16 P2 c1nc(c2c(n....
3 2PMK - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
4 1XEF - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
5 2FF7 Kd = 7.1 uM ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
6 2FFA - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
7 1JJ7 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
8 3NHA - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
9 3NHB - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
10 3NH9 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
11 2IXE - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
12 2IXF - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
13 4U00 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
14 1L2T Kd ~ 800 uM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ATP; Similar ligands found: 422
No: Ligand ECFP6 Tc MDL keys Tc
1 HEJ 1 1
2 ATP 1 1
3 5FA 0.985507 1
4 AQP 0.985507 1
5 AP5 0.927536 0.971831
6 B4P 0.927536 0.971831
7 BA3 0.913043 0.971831
8 ADP 0.9 1
9 A2D 0.884058 0.971831
10 AGS 0.84 0.945946
11 SAP 0.84 0.945946
12 6YZ 0.833333 0.972222
13 AT4 0.810811 0.958904
14 AN2 0.810811 0.985915
15 25L 0.809524 0.985915
16 AR6 0.802632 0.971831
17 APR 0.802632 0.971831
18 M33 0.8 0.958333
19 ACQ 0.794872 0.972222
20 TAT 0.794872 0.958904
21 T99 0.794872 0.958904
22 AD9 0.792208 0.972222
23 ACP 0.789474 0.972222
24 AMP 0.788732 0.971429
25 A 0.788732 0.971429
26 ANP 0.772152 0.972222
27 CA0 0.753247 0.945205
28 ADX 0.753247 0.873418
29 A22 0.746988 0.985915
30 50T 0.74359 0.958333
31 PRX 0.734177 0.893333
32 APC 0.734177 0.958904
33 ABM 0.733333 0.917808
34 ATF 0.731707 0.958904
35 ITT 0.730769 0.943662
36 7D4 0.730769 0.905405
37 ADQ 0.729412 0.945205
38 A3R 0.729412 0.907895
39 AP2 0.714286 0.958904
40 A12 0.714286 0.958904
41 A1R 0.709302 0.907895
42 SRA 0.706667 0.918919
43 5AL 0.698795 0.931507
44 HFD 0.695122 0.945946
45 9X8 0.693182 0.92
46 OAD 0.693182 0.945205
47 AU1 0.6875 0.972222
48 SRP 0.682353 0.906667
49 G5P 0.680851 0.921053
50 25A 0.678161 0.971831
51 3OD 0.677778 0.945205
52 4AD 0.670455 0.92
53 G3A 0.670213 0.921053
54 00A 0.662921 0.883117
55 RBY 0.662651 0.932432
56 ADP PO3 0.662651 0.943662
57 ADV 0.662651 0.932432
58 BIS 0.659341 0.933333
59 8QN 0.659091 0.931507
60 5SV 0.659091 0.848101
61 OOB 0.659091 0.931507
62 GTA 0.65625 0.886076
63 UP5 0.653061 0.92
64 AMO 0.651685 0.932432
65 PAJ 0.651685 0.884615
66 2A5 0.650602 0.918919
67 MAP 0.647727 0.945946
68 3AT 0.647059 0.971831
69 AHX 0.644444 0.896104
70 DLL 0.644444 0.931507
71 ATR 0.642857 0.971429
72 PAP 0.642857 0.985714
73 PTJ 0.641304 0.896104
74 7D3 0.6375 0.905405
75 3UK 0.637363 0.918919
76 SON 0.634146 0.932432
77 A4P 0.633663 0.843373
78 ALF ADP 0.632184 0.87013
79 ADP ALF 0.632184 0.87013
80 PR8 0.630435 0.85
81 WAQ 0.630435 0.883117
82 LAD 0.630435 0.860759
83 B5V 0.630435 0.906667
84 AFH 0.628866 0.884615
85 LMS 0.628205 0.82716
86 GAP 0.627907 0.893333
87 DTP 0.627907 0.905405
88 VO4 ADP 0.625 0.931507
89 ADP VO4 0.625 0.931507
90 TXA 0.623656 0.932432
91 ME8 0.623656 0.839506
92 1ZZ 0.623656 0.839506
93 NB8 0.623656 0.896104
94 FYA 0.623656 0.905405
95 DQV 0.622449 0.958333
96 T5A 0.621359 0.841463
97 ADN 0.619718 0.84507
98 RAB 0.619718 0.84507
99 XYA 0.619718 0.84507
100 DAL AMP 0.611111 0.905405
101 9SN 0.610526 0.871795
102 48N 0.61 0.896104
103 AP0 0.607843 0.896104
104 9ZD 0.604396 0.907895
105 9ZA 0.604396 0.907895
106 FA5 0.604167 0.906667
107 B5M 0.604167 0.894737
108 YAP 0.604167 0.894737
109 B5Y 0.604167 0.894737
110 NAI 0.60396 0.907895
111 6V0 0.60396 0.896104
112 TXD 0.60396 0.907895
113 DND 0.60396 0.932432
114 NXX 0.60396 0.932432
115 NAX 0.60396 0.873418
116 ADP BMA 0.602151 0.918919
117 A2R 0.6 0.985915
118 OMR 0.598039 0.851852
119 TXE 0.598039 0.907895
120 XAH 0.597938 0.839506
121 7DT 0.593023 0.985714
122 AOC 0.592593 0.821918
123 4UV 0.591837 0.894737
124 DDS 0.590909 0.878378
125 139 0.590476 0.873418
126 CNA 0.584906 0.932432
127 6AD 0.58427 0.909091
128 5AS 0.583333 0.77907
129 5N5 0.581081 0.819444
130 GA7 0.58 0.906667
131 4UU 0.58 0.894737
132 4TC 0.576923 0.896104
133 ADJ 0.575472 0.851852
134 5CD 0.573333 0.805556
135 A4D 0.573333 0.819444
136 RGT 0.571429 0.958904
137 A3P 0.571429 0.971429
138 7D5 0.56962 0.878378
139 LAQ 0.568627 0.839506
140 F2R 0.564815 0.864198
141 80F 0.563636 0.841463
142 YLP 0.563107 0.819277
143 A A 0.5625 0.944444
144 UPA 0.561905 0.907895
145 AV2 0.56044 0.917808
146 COD 0.559633 0.811765
147 4UW 0.557692 0.860759
148 JB6 0.556701 0.883117
149 3AM 0.555556 0.929577
150 ATP A A A 0.555556 0.930556
151 A2P 0.552941 0.957143
152 TYM 0.552381 0.906667
153 NA7 0.552083 0.958904
154 EP4 0.551282 0.753247
155 MYR AMP 0.55102 0.817073
156 PPS 0.549451 0.873418
157 YLC 0.54717 0.839506
158 YLB 0.54717 0.819277
159 NAD 0.545455 0.931507
160 DAT 0.545455 0.905405
161 TYR AMP 0.544554 0.87013
162 G5A 0.544444 0.77907
163 M2T 0.544304 0.734177
164 DTA 0.544304 0.786667
165 3DH 0.54321 0.773333
166 128 0.542857 0.776471
167 AHZ 0.538462 0.817073
168 GTP 0.537634 0.92
169 SSA 0.537634 0.8
170 MTA 0.5375 0.773333
171 IOT 0.537037 0.831325
172 A3D 0.535714 0.918919
173 ARG AMP 0.533981 0.829268
174 7MD 0.533981 0.8625
175 AR6 AR6 0.533981 0.917808
176 YLA 0.53211 0.819277
177 AMP DBH 0.529412 0.893333
178 IMO 0.529412 0.929577
179 TAD 0.528846 0.884615
180 AYB 0.527273 0.809524
181 A5A 0.526882 0.807229
182 HDV 0.526882 0.893333
183 TSB 0.526316 0.819277
184 EAD 0.525424 0.873418
185 2AM 0.52439 0.943662
186 6RE 0.52381 0.759494
187 7DD 0.522727 0.985714
188 V3L 0.521739 0.971831
189 AVV 0.520833 0.896104
190 BTX 0.517857 0.841463
191 NAE 0.517241 0.894737
192 52H 0.515789 0.77907
193 54H 0.515789 0.788235
194 VMS 0.515789 0.788235
195 NSS 0.515464 0.8
196 BT5 0.513274 0.831325
197 NAQ 0.512821 0.871795
198 ZAS 0.511905 0.766234
199 J7C 0.511628 0.769231
200 A3N 0.511628 0.786667
201 5X8 0.511111 0.763158
202 53H 0.510417 0.77907
203 8X1 0.510417 0.752809
204 5CA 0.510417 0.8
205 NVA LMS 0.510204 0.752809
206 ARU 0.510204 0.860759
207 AF3 ADP 3PG 0.509259 0.8375
208 ZID 0.508475 0.918919
209 P1H 0.508197 0.851852
210 OVE 0.505882 0.905405
211 S4M 0.505747 0.666667
212 LEU LMS 0.50505 0.752809
213 LPA AMP 0.504673 0.817073
214 7MC 0.504587 0.841463
215 DZD 0.5 0.884615
216 FB0 0.5 0.804598
217 MAO 0.5 0.759036
218 DSZ 0.5 0.8
219 LSS 0.5 0.761364
220 DSH 0.5 0.725
221 P5A 0.5 0.744444
222 NDE 0.495935 0.932432
223 N0B 0.495798 0.819277
224 M24 0.495726 0.85
225 YLY 0.495726 0.809524
226 NJP 0.495575 0.945946
227 9K8 0.49505 0.714286
228 MGP 0.494737 0.884615
229 6C6 0.494624 0.881579
230 NAJ PZO 0.491379 0.848101
231 0WD 0.491228 0.921053
232 6G0 0.489583 0.884615
233 GJV 0.488636 0.75
234 6FA 0.488189 0.841463
235 5AD 0.486842 0.746479
236 KAA 0.485149 0.752809
237 GSU 0.485149 0.77907
238 71V 0.483146 0.907895
239 NEC 0.482759 0.746667
240 A3G 0.482759 0.8
241 ODP 0.482456 0.909091
242 FAS 0.48062 0.851852
243 FAD 0.48062 0.851852
244 7D7 0.480519 0.743243
245 FDA 0.480315 0.833333
246 N6P 0.48 0.915493
247 2SA 0.479167 0.932432
248 GP3 0.478723 0.921053
249 4TA 0.478261 0.807229
250 SFG 0.478261 0.75
251 G A A A 0.478261 0.871795
252 AMP NAD 0.478261 0.905405
253 NPW 0.477876 0.886076
254 NDP 0.477876 0.921053
255 NDC 0.47619 0.871795
256 YSA 0.47619 0.77907
257 NAJ PYZ 0.475 0.807229
258 MGO 0.474227 0.860759
259 GDP 0.473684 0.92
260 NZQ 0.473684 0.909091
261 TXP 0.473684 0.921053
262 6IA 0.473684 0.8375
263 A7D 0.472527 0.776316
264 SFD 0.469231 0.734043
265 A5D 0.468085 0.786667
266 SA8 0.468085 0.707317
267 ZDA 0.468085 0.864865
268 12D 0.46789 0.785714
269 PGS 0.467391 0.883117
270 MHZ 0.467391 0.697674
271 8PZ 0.466667 0.8
272 62F 0.466165 0.8625
273 DA 0.465909 0.878378
274 D5M 0.465909 0.878378
275 GGZ 0.464646 0.825
276 SAH 0.463158 0.74359
277 SAI 0.463158 0.734177
278 FAY 0.462687 0.8625
279 Y3J 0.4625 0.726027
280 PO4 PO4 A A A A PO4 0.460784 0.902778
281 AAM 0.460674 0.971429
282 RFL 0.459259 0.821429
283 SMM 0.459184 0.686047
284 HF7 0.459184 0.893333
285 AMZ 0.458824 0.916667
286 C2R 0.458824 0.90411
287 SAM 0.458333 0.690476
288 A3S 0.456522 0.810811
289 FNK 0.455224 0.804598
290 U A 0.453782 0.907895
291 7C5 0.453704 0.818182
292 EEM 0.453608 0.690476
293 AAT 0.453608 0.707317
294 XNP 0.452991 0.873418
295 A G 0.452991 0.883117
296 PRT 0.45283 0.931507
297 AIR 0.451219 0.901408
298 62X 0.45098 0.666667
299 DCA 0.45 0.823529
300 ETB 0.45 0.833333
301 GSP 0.45 0.873418
302 U A G G 0.449153 0.883117
303 NIA 0.448276 0.822785
304 A3T 0.446809 0.821918
305 A A A 0.446602 0.905405
306 K15 0.446602 0.682353
307 PUA 0.446281 0.884615
308 6K6 0.445545 0.930556
309 GEK 0.445545 0.7375
310 4YB 0.445455 0.761364
311 S7M 0.444444 0.690476
312 Z5A 0.443548 0.77907
313 1DG 0.443548 0.921053
314 DG1 0.443548 0.921053
315 0T1 0.442623 0.823529
316 COA 0.442623 0.823529
317 WSA 0.442478 0.788235
318 8BR 0.43956 0.906667
319 8Q2 0.438596 0.772727
320 101 0.438202 0.878378
321 IDP 0.4375 0.918919
322 NVA 2AD 0.4375 0.759494
323 9JJ 0.435714 0.8625
324 NAP 0.435484 0.945205
325 APU 0.434783 0.894737
326 A U 0.434783 0.87013
327 7RP 0.433333 0.928571
328 A6D 0.432692 0.722892
329 AMX 0.432 0.833333
330 J7V 0.432 0.833333
331 TAP 0.432 0.907895
332 COS 0.432 0.804598
333 CAO 0.432 0.795455
334 30N 0.432 0.752688
335 V1N 0.431193 0.917808
336 649 0.429825 0.744444
337 P5F 0.429577 0.823529
338 NA0 0.428571 0.932432
339 SCO 0.428571 0.823529
340 CMX 0.428571 0.823529
341 7RA 0.428571 0.957747
342 0UM 0.427184 0.698795
343 GAV 0.427184 0.884615
344 QQY 0.426966 0.815789
345 1RB 0.426966 0.885714
346 ACK 0.426966 0.861111
347 G1R 0.425743 0.907895
348 GCP 0.425743 0.896104
349 FAM 0.425197 0.804598
350 FCX 0.425197 0.795455
351 ACO 0.425197 0.795455
352 GNH 0.424242 0.907895
353 F2N 0.423611 0.813953
354 GKE 0.422018 0.884615
355 GDD 0.422018 0.884615
356 GDC 0.422018 0.884615
357 HAX 0.421875 0.804598
358 3AD 0.421687 0.805556
359 9GM 0.421569 0.896104
360 GNP 0.421569 0.896104
361 FA9 0.42069 0.864198
362 TM1 0.420561 0.77381
363 KB1 0.420561 0.698795
364 H6Y 0.42 0.945205
365 2MC 0.419847 0.769231
366 3KK 0.418605 0.804598
367 FYN 0.418605 0.823529
368 S8M 0.417476 0.759494
369 7L1 0.417323 0.795455
370 2VA 0.416667 0.8
371 26A 0.416667 0.763158
372 NHD 0.416667 0.905405
373 QQX 0.41573 0.805195
374 CA6 0.415385 0.729167
375 OXK 0.415385 0.804598
376 COK 0.415385 0.804598
377 SOP 0.415385 0.804598
378 MCD 0.415385 0.804598
379 YE1 0.413534 0.813953
380 RMB 0.413043 0.873239
381 FAI 0.413043 0.916667
382 AS 0.413043 0.833333
383 CO6 0.412214 0.804598
384 1VU 0.412214 0.795455
385 CMC 0.412214 0.804598
386 NMX 0.412214 0.76087
387 SXZ 0.411215 0.710843
388 ANZ 0.410714 0.8
389 SCA 0.410448 0.804598
390 CAJ 0.409091 0.804598
391 SCD 0.409091 0.823529
392 EO7 0.408602 0.788235
393 D3Y 0.407767 0.789474
394 CC5 0.407407 0.816901
395 KH3 0.40708 0.674419
396 A C A C 0.406504 0.848101
397 SLU 0.406504 0.770115
398 G 0.40625 0.906667
399 5GP 0.40625 0.906667
400 A1S 0.406015 0.804598
401 IVC 0.406015 0.813953
402 MLC 0.406015 0.804598
403 3HC 0.406015 0.813953
404 1HE 0.406015 0.786517
405 BCO 0.406015 0.804598
406 GTG 0.405405 0.886076
407 NMN AMP PO4 0.404959 0.87013
408 3D1 0.404762 0.773333
409 3L1 0.404762 0.773333
410 2BA 0.404255 0.915493
411 CMP 0.404255 0.901408
412 VRT 0.40404 0.769231
413 SO8 0.40404 0.789474
414 MCA 0.402985 0.795455
415 COO 0.402985 0.804598
416 CAA 0.402985 0.813953
417 3NZ 0.401869 0.782051
418 G2R 0.401869 0.884615
419 ZZB 0.4 0.77381
420 2FA 0.4 0.813333
421 MC4 0.4 0.76087
422 2CP 0.4 0.795455
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2IXE; Ligand: ATP; Similar sites found with APoc: 626
This union binding pocket(no: 1) in the query (biounit: 2ixe.bio1) has 45 residues
No: Leader PDB Ligand Sequence Similarity
1 1QF9 ALF None
2 1QF9 ADP None
3 1QF9 C5P None
4 2IL4 COA None
5 5FII PHE None
6 5KSP GDP 1.05263
7 4Z7X 3CX 1.68067
8 3LRE ADP 1.84502
9 4ZNL BEF ADP 1.84502
10 3Q9L ATP 1.92308
11 5ZI9 FLC 1.92308
12 3IIS PID 1.98676
13 2HF9 GSP 2.21239
14 5LB3 ADP 2.21402
15 1SQ5 ADP 2.21402
16 4B47 GDP 2.21402
17 3KC1 2T6 2.21402
18 3DEF GDP 2.29008
19 2WHX ADP 2.58303
20 2JLR ANP 2.58303
21 3BOS CDP 2.58303
22 1PUJ GNP 2.58303
23 1G8S MET 2.6087
24 4RD0 GDP 2.6506
25 1IG3 VIB 2.6616
26 1O8B ABF 2.73973
27 2FNA ADP 2.80112
28 6AIC AMP 2.80374
29 4U5X GNP 2.80899
30 2A5F GTP 2.85714
31 1VG8 GNP 2.89855
32 4J0Q GDP 2.95203
33 5ZBR ANP 2.95203
34 4IHQ ADP 2.95203
35 2WOJ ADP ALF 2.95203
36 3ZS9 ADP ALF 2.95203
37 4R43 GDP 2.95203
38 5AK0 8V1 2.95203
39 1ZCB GDP 2.95203
40 4IDN GNP 2.95203
41 6A20 ADP 2.95203
42 6H3O FAD 2.95203
43 3GDN FAD 2.95203
44 3GDN HBX 2.95203
45 3LAD FAD 2.95203
46 1H65 GDP 2.96296
47 2O66 FLC 2.96296
48 1CM0 COA 2.97619
49 1D2E GDP 3.02267
50 3A4M ADP 3.07692
51 3N5C GDP 3.08642
52 2QN6 GDP 3.22581
53 1VG1 GDP 3.24324
54 1NN5 2DT 3.25581
55 1NN5 ANP 3.25581
56 2FH5 GTP 3.27103
57 1S7N COA 3.2967
58 3T5G GDP 3.31492
59 1M7G AV2 3.31754
60 1M7G ADX 3.31754
61 1M7G ADP 3.31754
62 5GOE GDP 3.32103
63 5XDR ADP 3.32103
64 3DC4 ADP 3.32103
65 4HSE ADP 3.32103
66 4LYA ATP 3.32103
67 5H4S RAM 3.32103
68 5W7Q GDP 3.32103
69 1DAR GDP 3.32103
70 1HSK FAD 3.32103
71 4R98 GNH 3.32103
72 5I34 GDP 3.32103
73 6BSX GDP 3.37079
74 6BSX E7S 3.37079
75 5E5U MLI 3.40909
76 1V0C ACO 3.46535
77 1V0C KNC 3.46535
78 3T1O GDP 3.53535
79 3H86 AP5 3.64583
80 4ITR GDP 3.66492
81 4NSQ COA 3.68421
82 4MKF AP5 3.68664
83 5TSH ADP 3.69004
84 5TSH ANP 3.69004
85 4FCW ADP 3.69004
86 5VHC BEF ADP 3.69004
87 5LTJ ADP 3.69004
88 4LJ9 ACP 3.69004
89 2XAU ADP 3.69004
90 5IRN ADP 3.69004
91 4PFO ADP 3.69004
92 4ZKD GDP 3.69004
93 1NAA ABL 3.69004
94 1NAA 6FA 3.69004
95 3IB1 IMN 3.69004
96 5M7P ADP 3.69004
97 1K6M AGS 3.69004
98 1U0J ADP 3.74532
99 5KSZ GCP 3.77358
100 1YRB GDP 3.81679
101 2QZ4 ADP 3.81679
102 4YC7 GNP 3.8674
103 1UJ2 ADP 3.96825
104 1UJ2 C5P 3.96825
105 1DAK ADP 4.01786
106 1DAK DPU 4.01786
107 3FKQ ATP 4.02145
108 3CPJ GDP 4.03587
109 1SKQ GDP 4.05904
110 2CE7 ADP 4.05904
111 3EWA ANP 4.05904
112 1RRC ADP 4.05904
113 6FAA ADP 4.05904
114 5M04 GDP 4.05904
115 4Y4V DAL 4.05904
116 1E2K TMC 4.05904
117 3WYA GDP 4.05904
118 5FG3 GDP 4.05904
119 5YT0 GDP 4.05904
120 3WY9 GDP 4.05904
121 3ITJ CIT 4.05904
122 3GJ7 GDP 4.0724
123 3GJ4 GDP 4.0724
124 3GJ8 GDP 4.0724
125 3CH5 GDP 4.16667
126 1BO4 COA 4.16667
127 1KAO GDP 4.19162
128 3CNL GNP 4.19847
129 1Z06 GNP 4.2328
130 5U32 GDP 4.23729
131 2PL3 ADP 4.23729
132 3A1S GDP 4.26357
133 3B7G ANP 4.34783
134 2ZFI ADP 4.37158
135 3T12 GDP ALF 4.41176
136 1V8K ANP 4.42804
137 1XMV ADP 4.42804
138 1KK1 GNP 4.42804
139 1FNN ADP 4.42804
140 3VMF GTP 4.42804
141 1X6V ADP 4.42804
142 5UPK GNP 4.42804
143 2BEK ATP 4.42804
144 4FRZ ADP 4.42804
145 2RCN GDP 4.42804
146 1F9V ADP 4.42804
147 2WIC GNP 4.42804
148 5J1J ANP 4.42804
149 5SXS NIZ 4.42804
150 3IIJ ADP 4.44444
151 2GNK ATP 4.46429
152 2F5X ASP 4.48718
153 4OHU NAD 4.49827
154 4OHU 2TK 4.49827
155 5XKT GNP 4.5
156 4LPS GDP 4.54545
157 5O74 GDP 4.56853
158 3NKV GNP 4.57143
159 1Z83 AP5 4.59184
160 1TQ4 GDP 4.60048
161 4TTQ ATP 4.65116
162 2VB6 ADP BEF 4.69799
163 1EK0 GNP 4.70588
164 2J0V GDP 4.71698
165 1Z2A GDP 4.7619
166 3X1Z GNP 4.79042
167 5W76 GDP 4.79705
168 6AU6 GDP 4.79705
169 3FYH ADP 4.79705
170 1CS4 GSP 4.79705
171 4Q1A UDP 4.79705
172 4Q1A 2XZ 4.79705
173 2C77 GNP 4.79705
174 4KVA GTP 4.79705
175 2C78 GNP 4.79705
176 4OHY ANP 4.79705
177 5HPY GDP 4.79705
178 1GOJ ADP 4.79705
179 2ZPA ADP 4.79705
180 5HR5 ADP 4.79705
181 1G7S GDP 4.79705
182 6HKE LMR 4.79705
183 1NY5 ADP 4.79705
184 1LDN FBP 4.79705
185 2FAH GDP 4.79705
186 6HKE MLT 4.79705
187 3IUY AMP 4.82456
188 3RWO GDP 4.86486
189 5G41 AP5 4.93274
190 1Z0F GDP 5.02793
191 1WWZ ACO 5.03145
192 3E5H GNP 5.05618
193 1ZIN AP5 5.06912
194 1S3G AP5 5.06912
195 4MKG AP5 5.06912
196 5Z2M GTP 5.07246
197 2ORV 4TA 5.12821
198 4X8O AP5 5.14019
199 2XTZ GSP 5.16605
200 4XGU ADP 5.16605
201 1SVK ALF GDP 5.16605
202 1BH2 GSP 5.16605
203 5JCP GDP ALF 5.16605
204 4NE2 SH2 5.16605
205 4NE2 ADP 5.16605
206 3RC3 ANP 5.16605
207 2VVG ADP 5.16605
208 1W5T ANP 5.16605
209 3LTW HLZ 5.16605
210 2J5V PCA 5.16605
211 2OZE AGS 5.16605
212 4IEE AGS 5.16605
213 3IO3 ADP 5.16605
214 2AJ4 GLA 5.16605
215 1W5T ADP 5.16605
216 3QBT GNP 5.17241
217 4LHW GNP 5.17241
218 2W83 GTP 5.19481
219 3DOE GTP 5.20833
220 1XX6 ADP 5.2356
221 4QRH 0O2 5.2381
222 4YDS ATP 5.26316
223 2UVO NAG 5.26316
224 5UIV ADP 5.28634
225 5G3Y ADP 5.30973
226 1ZD9 GDP 5.31915
227 2RGX AP5 5.33981
228 1GWN GTP 5.36585
229 1KSH GDP 5.37634
230 4NON GDP 5.38462
231 3W5J GDP 5.39216
232 1G41 ADP 5.40541
233 3AQ4 GDP 5.43478
234 2ZR9 DTP 5.44413
235 4V03 ADP 5.44747
236 1KY3 GDP 5.49451
237 2EFE GNH 5.52486
238 2BIF SIN 5.53506
239 2NCD ADP 5.53506
240 2BIF ANP 5.53506
241 2VOH CIT 5.53506
242 4YS0 ADP 5.53506
243 1VKJ A3P 5.53506
244 1EFV FAD 5.53506
245 1EFV AMP 5.53506
246 1FL2 FAD 5.53506
247 3FB4 AP5 5.55556
248 4BQS K2Q 5.68182
249 4BQS ADP 5.68182
250 1HTW ADP 5.6962
251 4YLG GDP 5.78035
252 5KUT GDP 5.82011
253 3U6B GDP 5.83756
254 4PC3 GDP 5.83756
255 5JBQ GDP 5.83756
256 4G5G GDP 5.83756
257 3U6K GDP 5.83756
258 2B4B COA 5.84795
259 2BVN GNP 5.85242
260 1D8T GDP 5.85242
261 4U8P UDP 5.90406
262 5FHD ADP ALF 5.90406
263 4PX9 ADP 5.90406
264 5FTB ANP 5.90406
265 3EZ2 ADP 5.90406
266 5MZN ADP 5.90406
267 5WC2 ADP 5.90406
268 2C9O ADP 5.90406
269 4NCN GTP 5.90406
270 4P4T GDP 5.90406
271 1Q19 SSC 5.90406
272 4TMZ GSP 5.90406
273 4RZ3 ADP 5.90406
274 1OYY AGS 5.90406
275 1F5N GNP 5.90406
276 3VSS FRU 5.90406
277 1AKY AP5 5.90909
278 4XOI GTP 5.92593
279 4KVG GTP 5.95238
280 2ZTS ADP 5.9761
281 1M7B GTP 5.97826
282 1GUA GNP 5.98802
283 4XTR ATP 5.99078
284 4XVU ATP 5.99078
285 4XTR ADP 5.99078
286 3Q72 GNP 6.0241
287 1O3Y GTP 6.0241
288 2J59 GTP 6.0241
289 1J2J GTP 6.0241
290 4P3Y GDP 6.04396
291 5OEC GDP 6.09137
292 3AB3 GDP 6.09756
293 1W4R TTP 6.15385
294 2CHG ANP 6.19469
295 5CK5 GDP 6.27306
296 5L3V GDP 6.27306
297 1CR1 TTP 6.27306
298 5A1S FLC 6.27306
299 2A2C ADP 6.27306
300 2A2C NG1 6.27306
301 6AM8 TRP 6.27306
302 2X77 GDP 6.34921
303 1DNP MHF 6.36943
304 3CX8 GSP 6.40394
305 1VHT BA3 6.42202
306 2W58 ADP 6.43564
307 2GCO GNP 6.46766
308 2GCN GDP 6.46766
309 1Z08 GNP 6.47059
310 4BAS GNP 6.53266
311 1ZUI SKM 6.54762
312 1W7J ADP BEF 6.62252
313 5H68 AGS 6.64207
314 2OG2 MLI 6.64207
315 3B9Q MLI 6.64207
316 3E70 GDP 6.64207
317 1WA5 GTP 6.64207
318 2WKQ GTP 6.64207
319 1RJ9 GCP 6.64207
320 1IN4 ADP 6.64207
321 3GJX GTP 6.64207
322 5L3R GCP 6.64207
323 4TVD BGC 6.64207
324 1RE0 GDP 6.78733
325 5MVR ADP 6.79012
326 1M2O GNP 6.84211
327 3TMK T5A 6.94444
328 1LVK MNT BEF 7.01107
329 5H7J GCP 7.01107
330 1Z6T ADP 7.01107
331 6B4K ANP 7.01107
332 1VG0 GDP 7.01107
333 1VG9 GDP 7.01107
334 1MKY GDP 7.01107
335 3TK1 GDP 7.01107
336 1RV0 NDG 7.01107
337 3Q9T FAY 7.01107
338 4D0N GDP 7.02703
339 6BCA GSP 7.02703
340 3LXR GDP 7.02703
341 2IYL GDP 7.04225
342 4UXH T5A 7.06522
343 4GOJ GNP 7.08333
344 4V0K GDP 7.10059
345 3Q85 GNP 7.10059
346 4WOP CTP 7.11111
347 4R2I ANP 7.14286
348 5NM7 GLY 7.14286
349 3BC1 GNP 7.17949
350 4JLS 3ZE 7.23684
351 3AB4 THR 7.30337
352 3FWY ADP 7.32484
353 4CVN ADP 7.32984
354 1OIX GDP 7.32984
355 1OIV GDP 7.32984
356 6BC0 GSP 7.33333
357 4ZG4 VO4 ADP 7.38007
358 2Q2Y ADP 7.38007
359 2Q2Y MKR 7.38007
360 1XP8 AGS 7.38007
361 4D81 ADP 7.38007
362 4PJ3 ANP 7.38007
363 2WJG GDP 7.44681
364 4HI0 GDP 7.53769
365 4QOS ADP 7.54717
366 5EE5 GTP 7.60234
367 1UPT GTP 7.60234
368 2ZEJ GDP 7.6087
369 3BER AMP 7.63052
370 6G47 SIA 7.6555
371 2F3R G5P 7.72947
372 1T5C ADP 7.73639
373 5FJJ MAN 7.74908
374 1FP6 ADP 7.74908
375 4WZA ACP 7.74908
376 4WZA ADP 7.74908
377 4XSH GSP 7.76256
378 2QTV GNP 7.78443
379 2PEZ DAT 7.82123
380 2PEZ GGZ 7.82123
381 5JCZ GDP 7.82123
382 3KJI ADP 7.87402
383 1R4A GNP 7.87879
384 4LX0 BEF GDP 7.9096
385 2CDN ADP 7.9602
386 3LL5 IP8 8.03213
387 1LVG ADP 8.08081
388 1D2N ANP 8.08823
389 4C4P GNP 8.09249
390 3COB ADP 8.11808
391 2Y65 ADP 8.11808
392 5BN3 ADP 8.11808
393 5W75 SUC 8.11808
394 5W75 GDP 8.11808
395 5H7K GDP 8.11808
396 2GKS ADP 8.11808
397 3P4X ADP 8.11808
398 4UMJ BFQ 8.11808
399 5GVR LMR 8.11966
400 3H4S ADP 8.14815
401 1B7T ADP 8.33333
402 1S9D GDP 8.37438
403 5HCN GCP 8.42912
404 2WJH GDP 8.43373
405 2WJH FLC 8.43373
406 2XT3 ADP 8.48709
407 5Y6N ADP 8.48709
408 2OBM ADP 8.48709
409 3PCR GTP 8.48709
410 1OFH ADP 8.48709
411 4WEI GLC GAL 8.48709
412 2IS6 ADP 8.48709
413 1G7C 5GP 8.48709
414 4D0G GTP 8.57143
415 1ION ADP 8.64198
416 3QXC ATP 8.67769
417 1OE0 TTP 8.69565
418 5WDR GNP 8.77193
419 1TU3 GNP 8.77193
420 3GJ5 GDP 8.82353
421 1G16 GDP 8.82353
422 1R2Q GNP 8.82353
423 1SVM ATP 8.85609
424 4OI4 ATP 8.85609
425 3BFV ADP 8.85609
426 4H1V GNP 8.85609
427 5IFS ADP 8.86076
428 1RYH GNP 8.86699
429 3DZD ADP 8.96739
430 1ZJ6 G3D 9.09091
431 3GJ3 GDP 9.09091
432 2GAG NAD 9.09091
433 2W2X GSP 9.18919
434 2HT6 GDP 9.1954
435 1JJV ATP 9.2233
436 4HDQ GNP 9.22509
437 4HDO GNP 9.22509
438 2CK3 ADP 9.22509
439 1W0J ADP BEF 9.22509
440 2CK3 ANP 9.22509
441 1W0J ADP 9.22509
442 5TUK FAD 9.22509
443 5EXT ADP 9.23077
444 1KK8 BEF ADP 9.35252
445 1I4D GDP 9.375
446 1E96 GTP 9.375
447 1XKV ATP 9.5941
448 3WXM GTP 9.5941
449 5MIT FAD 9.5941
450 5MIT NAP 9.5941
451 3TNF GNP 9.5941
452 3SBD GNP 9.62567
453 1MH1 GNP 9.67742
454 4E03 ADP 9.70874
455 2BCG GDP 9.70874
456 1KO8 6PG 9.71429
457 1G4U GDP 9.78261
458 5DI3 GNP 9.88593
459 4QM7 GTP 9.94152
460 1MR3 G3D 9.94475
461 5LEF GTP 9.94764
462 4GOX A3P 9.9631
463 2WMO GTP 9.9631
464 4ZI2 GNP 10
465 2YOH WMJ 10
466 2Y8E GNP 10.0559
467 1NRJ GTP 10.0917
468 1F6B GDP 10.101
469 5ZB0 ADP 10.101
470 5ZB0 TYD 10.101
471 3R96 AMP 10.1064
472 3R96 ACO 10.1064
473 2FJU GSP 10.1124
474 1G3Q ADP 10.1266
475 3DKP ADP 10.2041
476 1HE1 GDP 10.2273
477 4YJ1 ADP 10.3321
478 2FSH ANP 10.3321
479 2GK6 ADP 10.3321
480 1IHU ADP 10.3321
481 1IHU AF3 10.3321
482 3AD8 NAD 10.3321
483 1FZQ GDP 10.4972
484 2FFQ GSP 10.5263
485 2OFW ADX 10.5769
486 2V7Q ATP 10.6061
487 2V7Q ADP 10.6061
488 6CAM BGC 10.7011
489 1D8C SOR 10.7011
490 1YZN GNP 10.8108
491 1Y63 ADP 10.8696
492 5N69 ADP 11.0553
493 1WDT GTP 11.0701
494 4DCT GDP 11.0701
495 5K5Z ANP 11.0701
496 3SFV GDP 11.0701
497 5SZH GNP 11.1111
498 1YZQ GNP 11.1765
499 2D7D ADP 11.4391
500 4M9Q GNP 11.4537
501 2QG6 NMN 11.5578
502 5UQW GDP 11.6402
503 4KAX GTP 11.8012
504 6CRK GDP 11.8081
505 1Y3A GDP 11.8081
506 5TB5 GDP 11.8919
507 5TAR GDP 11.8919
508 1XPJ TLA 11.9048
509 3UIE ANP 12
510 5BQ5 ADP BEF 12.1693
511 5OCG GNP 12.1693
512 2ODE ALF GDP 12.1771
513 1NJF ADP 12.1771
514 1NJF AGS 12.1771
515 5VGR GDP 12.1771
516 2KIN ADP 12.1849
517 4TL6 ANP 12.253
518 1D5C GDP 12.3457
519 4NU0 AP5 12.4424
520 2QQ0 TMP 12.5
521 2QQ0 ADP 12.5
522 2QQ0 THM 12.5
523 2QQ0 ANP 12.5
524 5UWP GNP 12.5461
525 4HAT GNP 12.5461
526 3M1I GTP 12.5461
527 5UWI GNP 12.5461
528 5UWS GNP 12.5461
529 5UWU GNP 12.5461
530 5UWR GNP 12.5461
531 5UWQ GNP 12.5461
532 5UWT GNP 12.5461
533 5UWW GNP 12.5461
534 3WYF GTP 12.5461
535 5IRR GSP 12.5461
536 5DI9 GNP 12.5461
537 3PQC GDP 12.8205
538 4K81 GTP 12.8655
539 2BME GNP 12.9032
540 3TBK ANP 12.9151
541 1OS1 PYR 12.9151
542 1OS1 ATP 12.9151
543 3T34 GDP 12.9151
544 3LN9 FLC 12.9496
545 5J1S ATP 13.0081
546 5O2T GSP 13.0178
547 1CLU DBG 13.253
548 3KUD GDP 13.253
549 2UZI GTP 13.253
550 3DDC GNP 13.253
551 2C5L GTP 13.2948
552 2A9K GDP 13.369
553 1X1R GDP 13.4831
554 4DKX GDP 13.6531
555 1BG2 ADP 13.6531
556 5E95 GDP 13.6905
557 1P72 ADP 14.0221
558 2F9L GDP 14.0704
559 1UAD GNP 14.2857
560 1ZC3 GNP 14.2857
561 1FQJ GDP 14.2857
562 1FQJ ALF 14.2857
563 6BCB GSP 14.3836
564 3ZFD ANP 14.3911
565 1YTM ATP 14.3911
566 3MJH GTP 14.7059
567 3QKT ANP 14.7601
568 1U8Z GDP 14.881
569 1DS6 GDP 15
570 1YZG GDP 15.0838
571 3TKL GTP 15.1292
572 1S8F GDP 15.8192
573 2EW1 GNP 15.9204
574 5H67 ATP 15.9574
575 3QF7 ANP 16
576 3ZIA ADP 16.5468
577 3ZIA ATP 16.5468
578 4DID GDP 16.5803
579 5KDO GDP 17.5676
580 2DPY ADP 17.7122
581 1UKZ ADP 17.734
582 1L7N AF3 18.0095
583 3WYG GTP 18.4211
584 4BFW ZVW 18.8679
585 5Z69 AGS 19.1882
586 6C90 ADP 19.2308
587 1XVB BHL 19.4118
588 2OM2 GDP 19.4444
589 3ZQ6 ADP ALF 19.5572
590 3KTA AP5 19.6532
591 5I0H ADP BEF 20.2952
592 2HCJ GDP 20.2952
593 1XEX ATP 20.3488
594 5L3S GNP 20.6081
595 5L3S G 20.6081
596 2A5J GDP 20.9424
597 2CJW GDP 21.875
598 1GXU 2HP 21.978
599 1Z0A GDP 22.4138
600 5L3W GDP 22.5092
601 1Z0J GTP 22.9412
602 1YVD GNP 23.6686
603 2NLQ GLY 25
604 5ZXD ATP 25.4613
605 5DIF GNP 26.3158
606 5DHF GNP 26.3158
607 4PPF FLC 26.9373
608 1F2U ATP 27.027
609 5UWH GNP 27.2727
610 1Z0K GTP 27.5362
611 6CIT GNP 28.5714
612 1G6H ADP 31.5175
613 4JLV ADP 33.2103
614 5UWO GNP 35
615 1OXV ANP 36.5314
616 1R0X ATP 39.1144
617 3RLF ANP 39.4834
618 2AWN ADP 39.4834
619 5X40 ACP 40.2214
620 3FVQ ATP 40.9594
621 4WZ6 ATP 41.3284
622 1JI0 ATP 42.9167
623 1B0U ATP 44.2748
624 6B8B ADP 45.3815
625 2CBZ ATP 45.5696
626 2PZE ATP 47.1616
Pocket No.: 2; Query (leader) PDB : 2IXE; Ligand: ATP; Similar sites found with APoc: 70
This union binding pocket(no: 2) in the query (biounit: 2ixe.bio1) has 45 residues
No: Leader PDB Ligand Sequence Similarity
1 2PD4 NAD 1.10701
2 5TWB FAD 1.84502
3 4HE2 AMP 1.84502
4 5BSH PRO 1.84502
5 5HGZ MLA 2.05761
6 3CTY FAD 2.21402
7 2BHZ MAL 2.21402
8 4UXU MLK 2.29358
9 1AX2 NDG GAL 2.51046
10 4A4Z ANP 2.58303
11 2I6U CP 2.58303
12 3QVV A3P 2.58303
13 1H74 ADP 2.58303
14 5NXX 3Q7 2.61194
15 3R7F CP 2.95203
16 1V59 FAD 2.95203
17 5TCI MLI 2.95203
18 2V2V V12 3.32103
19 4B1W ATP 3.32103
20 3OJF NDP 3.50195
21 3OJF IMJ 3.50195
22 2ZX2 RAM 3.58974
23 5LTJ BEF 3.69004
24 2GN2 C5P 3.69004
25 3ENV ABF 3.82979
26 1TKU 5RP 3.92157
27 3JQQ A2P 4.05904
28 6APL C5P 4.05904
29 1C3V PDC 4.08163
30 4TMK T5A 4.22535
31 5WXU FLC 4.42804
32 6EGU 43Y 4.42804
33 1D4D FAD 4.42804
34 4CBX ATP 4.72441
35 3N9R TD3 4.79705
36 1YXM ADE 4.79705
37 1YAG ATP 4.8
38 5EB4 FAD 5.16605
39 4ZES MMA 5.44218
40 4YKG FAD 5.53506
41 4YKG NAD 5.53506
42 4AUT FAD 5.53506
43 1WUU GLA 5.76441
44 2JAQ DCP 5.85366
45 1PS9 FAD 5.90406
46 1NST A3P 5.90406
47 5K0A FAD 6.27306
48 6CS8 F9Y 6.27306
49 4RSL FAD 6.27306
50 4YAG NAI 7.01107
51 4P83 U5P 7.01107
52 1GPE FAD 8.11808
53 3L6C MLI 8.11808
54 2DVZ GLU 8.11808
55 2JBH 5GP 8.44444
56 6A4R ASP 8.67924
57 2ZE7 AMP 8.69565
58 2ZE7 DST 8.69565
59 2GAG FOA 9.09091
60 3JUC PCA 9.15033
61 5EZ7 FAD 9.22509
62 2Q8M AMP 9.5941
63 3U4L ATP 9.5941
64 5HV7 RBL 9.9631
65 3CIP ATP 9.9631
66 1HE1 AF3 10.2273
67 2B8T THM 11.6592
68 1O94 ADP 11.8081
69 5LLB 6YZ 12.1673
70 1T8U UAP SGN IDS SGN 19.5572
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