Receptor
PDB id Resolution Class Description Source Keywords
2I74 1.75 Å EC: 3.5.1.52 CRYSTAL STRUCTURE OF MOUSE PEPTIDE N-GLYCANASE C-TERMINAL DO COMPLEX WITH MANNOPENTAOSE MUS MUSCULUS BETA-SANDWICH HYDROLASE
Ref.: STRUCTURAL AND BIOCHEMICAL STUDIES OF THE C-TERMINA OF MOUSE PEPTIDE-N-GLYCANASE IDENTIFY IT AS A MANNOSE-BINDING MODULE. PROC.NATL.ACAD.SCI.USA V. 103 17214 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACT A:11;
A:14;
A:9;
B:10;
B:12;
B:13;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
none;
 submit data
59.044 C2 H3 O2 CC(=O...
GOL A:15;
A:17;
B:16;
 Invalid;
Invalid;
Invalid;
 none;
none;
none;
 submit data
92.094 C3 H8 O3 C(C(C...
MAN MAN MAN MAN C:1;
D:1;
 Valid;
Valid;
 none;
none;
 Kd ~ 67 uM
n/a n/a
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2I74 1.75 Å EC: 3.5.1.52 CRYSTAL STRUCTURE OF MOUSE PEPTIDE N-GLYCANASE C-TERMINAL DO COMPLEX WITH MANNOPENTAOSE MUS MUSCULUS BETA-SANDWICH HYDROLASE
Ref.: STRUCTURAL AND BIOCHEMICAL STUDIES OF THE C-TERMINA OF MOUSE PEPTIDE-N-GLYCANASE IDENTIFY IT AS A MANNOSE-BINDING MODULE. PROC.NATL.ACAD.SCI.USA V. 103 17214 2006
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2I74 Kd ~ 67 uM MAN MAN MAN MAN n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2I74 Kd ~ 67 uM MAN MAN MAN MAN n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2I74 Kd ~ 67 uM MAN MAN MAN MAN n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: MAN MAN MAN MAN; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Ligands (3D)
Ligand no: 1; Ligand: MAN MAN MAN MAN; Similar ligands found: 2
No: Ligand Similarity coefficient
1 MAN MAN MAN MAN 1.0000
2 BMA MAN MAN MAN 0.9508
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2I74; Ligand: MAN MAN MAN MAN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2i74.bio2) has 13 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback