Receptor
PDB id Resolution Class Description Source Keywords
2HPS 1.72 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF COELENTERAZINE-BINDING PROTEIN FROM REN MUELLERI RENILLA MUELLERI BIOLUMINESCENCE COELENTERAZINE-BINDING SOUTHEAST COLLABORASTRUCTURAL GENOMICS SECSG STRUCTURAL GENOMICS PSI PROTESTRUCTURE INITIATIVE LUMINESCENT PROTEIN
Ref.: CRYSTAL STRUCTURE OF COELENTERAZINE-BINDING PROTEIN RENILLA MUELLERI AT 1.7 A: WHY IT IS NOT A CALCIUM-PHOTOPROTEIN. PHOTOCHEM.PHOTOBIOL.SCI. V. 7 442 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CTZ A:187;
Valid;
none;
submit data
439.463 C26 H21 N3 O4 c1ccc...
GOL A:376;
A:377;
Invalid;
Invalid;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2HPS 1.72 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF COELENTERAZINE-BINDING PROTEIN FROM REN MUELLERI RENILLA MUELLERI BIOLUMINESCENCE COELENTERAZINE-BINDING SOUTHEAST COLLABORASTRUCTURAL GENOMICS SECSG STRUCTURAL GENOMICS PSI PROTESTRUCTURE INITIATIVE LUMINESCENT PROTEIN
Ref.: CRYSTAL STRUCTURE OF COELENTERAZINE-BINDING PROTEIN RENILLA MUELLERI AT 1.7 A: WHY IT IS NOT A CALCIUM-PHOTOPROTEIN. PHOTOCHEM.PHOTOBIOL.SCI. V. 7 442 2008
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 552 families.
1 2HPS - CTZ C26 H21 N3 O4 c1ccc(cc1)....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 426 families.
1 2HPS - CTZ C26 H21 N3 O4 c1ccc(cc1)....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 322 families.
1 2HPS - CTZ C26 H21 N3 O4 c1ccc(cc1)....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: CTZ; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 CTZ 1 1
2 CZH 0.721519 0.885246
3 9A3 0.617977 0.830769
Similar Ligands (3D)
Ligand no: 1; Ligand: CTZ; Similar ligands found: 3
No: Ligand Similarity coefficient
1 CZB 0.9511
2 CZP 0.9430
3 CZN 0.9261
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2HPS; Ligand: CTZ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2hps.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback