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Receptor
PDB id Resolution Class Description Source Keywords
2HFN 1.8 Å NON-ENZYME: SIGNAL_HORMONE CRYSTAL STRUCTURES OF THE SYNECHOCYSTIS PHOTORECEPTOR SLR169 DISTINCT STRUCTURAL STATES RELATED TO SIGNALING SYNECHOCYSTIS SP. BETA SHEET FERREDOXIN-LIKE FOLD FLAVIN BINDING PROTEIN PHOTORECEPTOR ELECTRON TRANSPORT
Ref.: CRYSTAL STRUCTURES OF THE SYNECHOCYSTIS PHOTORECEPT SLR1694 REVEAL DISTINCT STRUCTURAL STATES RELATED T SIGNALING. BIOCHEMISTRY V. 45 12687 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FMN A:201;
B:201;
C:201;
D:201;
E:201;
F:201;
G:201;
H:201;
I:201;
J:201;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
456.344 C17 H21 N4 O9 P Cc1cc...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2HFN 1.8 Å NON-ENZYME: SIGNAL_HORMONE CRYSTAL STRUCTURES OF THE SYNECHOCYSTIS PHOTORECEPTOR SLR169 DISTINCT STRUCTURAL STATES RELATED TO SIGNALING SYNECHOCYSTIS SP. BETA SHEET FERREDOXIN-LIKE FOLD FLAVIN BINDING PROTEIN PHOTORECEPTOR ELECTRON TRANSPORT
Ref.: CRYSTAL STRUCTURES OF THE SYNECHOCYSTIS PHOTORECEPT SLR1694 REVEAL DISTINCT STRUCTURAL STATES RELATED T SIGNALING. BIOCHEMISTRY V. 45 12687 2006
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 286 families.
1 2HFN - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
2 3MZI - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
3 2HFO - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 2HFN - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
2 3MZI - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
3 2HFO - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 149 families.
1 1X0P - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 2HFN - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
3 3MZI - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
4 2HFO - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FMN; Similar ligands found: 15
No: Ligand ECFP6 Tc MDL keys Tc
1 FMN 1 1
2 RBF 0.75641 0.876712
3 RS3 0.571429 0.831169
4 FAD 0.543307 0.876543
5 FAS 0.543307 0.876543
6 FAE 0.539062 0.865854
7 LFN 0.475 0.643836
8 C3F 0.473684 0.74359
9 CF4 0.463918 0.734177
10 FAY 0.446043 0.864198
11 FNR 0.444444 0.909091
12 RFL 0.442857 0.845238
13 4LS 0.411215 0.875
14 1VY 0.406593 0.769231
15 DLZ 0.404494 0.782051
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2HFN; Ligand: FMN; Similar sites found with APoc: 179
This union binding pocket(no: 1) in the query (biounit: 2hfn.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 1QNR MAB None
2 1DTL BEP None
3 5TVI MYR None
4 5N8V KZZ None
5 2Z77 HE7 None
6 1POC GEL None
7 4XU6 TDA None
8 1VBO MAN MAN MAN None
9 3KP6 SAL None
10 5FS0 5JC None
11 5A89 ADP None
12 3NUG NAD None
13 2YLD CMO None
14 3E85 BSU None
15 2QZT PLM None
16 2Z6C FMN None
17 5B09 4MX None
18 5K53 STE 1.30719
19 3AQT RCO 1.30719
20 2E2R 2OH 1.30719
21 4IAE 1DX 1.30719
22 2D5X L35 1.41844
23 4R38 RBF 1.42857
24 5SVV FMN 1.45985
25 4PGK Y69 1.96078
26 1R6N 434 1.96078
27 5M36 9SZ 1.96078
28 3B1M KRC 1.96078
29 3ZOK GLY 1.96078
30 3WLV AZA 1.96078
31 4B7P 9UN 1.96078
32 3FS1 MYR 1.96078
33 6BR8 6OU 1.96078
34 6BR8 PGV 1.96078
35 5I8F ML1 1.96078
36 5DJU FMN 2.06897
37 4DDY DN6 2.61438
38 4DE3 DN8 2.61438
39 3AJH BL3 2.61438
40 3T31 DCQ 2.61438
41 4GN8 ASO 2.61438
42 5H86 BCO 2.61438
43 4RYV ZEA 2.61438
44 3GZ9 D32 2.61438
45 1H5T DAU 2.61438
46 1EWF PC1 3.26797
47 2C78 PUL 3.26797
48 3W68 VIV 3.26797
49 1XSE NDP 3.26797
50 3SAO NKN 3.26797
51 5OLK DTP 3.26797
52 6AYI C3G 3.26797
53 3B6C SDN 3.26797
54 4TR9 38D 3.26797
55 2P1C GG3 3.33333
56 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 3.92157
57 5NM7 GLY 3.92157
58 4RC8 STE 3.92157
59 1R5L VIV 3.92157
60 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 3.92157
61 3SFI 3SF 3.92157
62 4O1Z MXM 3.92157
63 4D06 NAR 3.92157
64 6D50 GCB 3.92157
65 4URN NOV 3.92157
66 4MRP GSH 4.57516
67 3D9F N6C 4.57516
68 4V24 GYR 4.57516
69 6GG9 FMN 4.57516
70 1VPV PLM 4.57516
71 1MGP PLM 4.57516
72 3D9F FAD 4.57516
73 6B3A SAM 4.57516
74 5J6A P46 4.57516
75 2HAW 2PN 4.57516
76 4MNS 2AX 4.57516
77 5W7B MYR 4.57516
78 1FDJ 13P 4.57516
79 3T58 FAD 4.57516
80 1TMO 2MD 4.57516
81 2P3C 3TL 5.05051
82 6DIO CIT 5.22876
83 3W5N RAM 5.22876
84 1TV5 N8E 5.22876
85 5HA0 LTD 5.22876
86 1NF8 BOG 5.22876
87 3P3G UKW 5.22876
88 3P3G 3P3 5.22876
89 5CXI 5TW 5.22876
90 1L5J TRA 5.22876
91 1RM0 NAI 5.22876
92 3NX2 FER 5.22876
93 4L9Z COA 5.22876
94 3KPE TM3 5.88235
95 3KFF XBT 5.88235
96 3KFF ZBT 5.88235
97 1DB1 VDX 5.88235
98 4Z3X 4KX 5.88235
99 4Z3X MTE 5.88235
100 5HGR 45D 5.88235
101 1UJ2 C5P 6.53595
102 3P7N FMN 6.53595
103 1XVB BHL 6.53595
104 4DNJ ANN 6.53595
105 3HYW DCQ 7.18954
106 3TDC 0EU 7.18954
107 3HQP OXL 7.18954
108 5B4B LP5 7.84314
109 1AUA BOG 7.84314
110 4P42 PEE 7.84314
111 5AAV GW5 8.49673
112 5AWV GHP 3MY 3FG GHP GHP OMY 3FG NAG MAN 8.49673
113 1Z8O DEB 8.49673
114 6EOZ 58K 8.49673
115 3RDE OYP 8.49673
116 1GNI OLA 9.15033
117 2VHW NAI 9.15033
118 3LN0 52B 9.15033
119 3BJC WAN 9.15033
120 1QY1 PRZ 9.15033
121 4R57 ACO 9.15033
122 3OVR 5SP 9.15033
123 5FYR INS 9.15033
124 4F7E 0SH 9.80392
125 2Z7I 742 9.80392
126 3L9R L9Q 9.80392
127 4NZF ARB 9.80392
128 2Z6D FMN 10
129 5N26 73M 10.4575
130 2E3N 6CM 10.4575
131 4HIA FMN 10.4575
132 3OV6 MK0 10.4575
133 6F6E PLM 10.4575
134 4DXJ IPE 11.1111
135 5C9J DAO 11.1111
136 4DXJ 0M9 11.1111
137 6MVU K4V 11.1111
138 4X6F 3XU 11.1111
139 2CW6 3HG 11.7647
140 2P7Q GG6 12.0301
141 4OGQ 7PH 12.4183
142 5EW0 3C7 12.4183
143 4OGQ UMQ 12.4183
144 3LDW ZOL 13.0719
145 1PZO CBT 13.0719
146 3LDW IPE 13.0719
147 5IVX ARG GLY PRO GLY ARG ALA PHE VAL THR ILE 13.7255
148 5OSW DIU 13.7255
149 4KVL PLM 14.3791
150 2QL9 CIT 14.433
151 4LY9 1YY 15.0327
152 4TM3 FAD 15.6863
153 4DO1 ANN 15.6863
154 1HBK MYR 15.7303
155 6GH1 ARG LEU PRO ALA LYS ALA PRO LEU LEU 16.3399
156 3G08 FEE 16.9935
157 3QUZ QUV 16.9935
158 3SCM LGN 16.9935
159 4YV5 SVR 17.2131
160 5WL1 CUY 17.6471
161 5WL1 D3D 17.6471
162 5U98 1KX 17.6471
163 4KWD JF2 18.9542
164 3QFJ LEU LEU PHE GLY PHE PRO VAL TYR VAL 18.9542
165 5Z84 PEK 19.5652
166 5ZCO CHD 19.5652
167 5JHD GLY ILE LEU GLY PHE VAL PHE THR LEU 19.6078
168 5KBE IPH 20.915
169 4CCN OGA 22.8571
170 3AVR OGA 22.8758
171 5TVM PUT 24.8366
172 4EES FMN 27.8261
173 2BYC FMN 30.6569
174 5TPV TYD 33.9869
175 3GFZ FMN 35.9477
176 4YUS FMN 37.9085
177 2IYG FMN 38.7097
178 5MBC FMN 41.8301
179 1YRX FMN 42.9752
Pocket No.: 2; Query (leader) PDB : 2HFN; Ligand: FMN; Similar sites found with APoc: 37
This union binding pocket(no: 2) in the query (biounit: 2hfn.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
1 4K55 H6P None
2 1UO5 PIH None
3 1MT1 AG2 None
4 3KDU NKS None
5 2QQC AG2 None
6 1N13 AG2 None
7 4O4Z N2O None
8 6CDG PRO GLY LEU TRP LYS SER None
9 1XZ3 ICF 1.96078
10 2XXP DSL 1.96078
11 4QWT ACD 1.96078
12 3BPX SAL 2.02703
13 3D72 FAD 3.3557
14 5XQL C2E 4.57516
15 2ZCQ B65 4.57516
16 2YIP YIO 5.07246
17 3B6R CRN 5.22876
18 5V4R MGT 5.22876
19 4EDF UPG 5.22876
20 2R5V HHH 5.88235
21 2WTN FER 5.88235
22 3UXL CFI 5.88235
23 2ZMF CMP 5.88235
24 1N9L FMN 6.42202
25 2BP1 FLC 6.94444
26 1I06 TZL 9.15033
27 5DKK FMN 9.65517
28 2UW1 GVM 9.80392
29 3T50 FMN 10.4575
30 4DW4 U5P 11.1111
31 4OCX MT1 11.7647
32 4OIV XX9 12.4183
33 1DLJ UGA 17.6471
34 5ISZ GLY ILE LEU GLY PHE VAL PHE THR LEU 18.9542
35 1OGA GLY ILE LEU GLY PHE VAL PHE THR LEU 18.9542
36 5Z84 CHD 19.5652
37 1T0S BML 27.907
Pocket No.: 3; Query (leader) PDB : 2HFN; Ligand: FMN; Similar sites found with APoc: 31
This union binding pocket(no: 3) in the query (biounit: 2hfn.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 1NU4 MLA None
2 1K7L 544 None
3 2AGC MYR 1.96078
4 5M37 9SZ 1.96078
5 2CJF RP4 1.96078
6 1PZL MYR 1.96078
7 2V0U FMN 2.05479
8 2WKQ FMN 2.61438
9 3VM7 GLC 3.26797
10 4XYB NDP 4.57516
11 5GUE GGS 4.57516
12 4Y9J UCC 5.22876
13 2XMY CDK 5.88235
14 2WR1 NAG 5.88235
15 4KBS PX2 5.88235
16 6BQ6 TER 6.53595
17 3MI3 LYS 7.84314
18 3E7O 35F 8.49673
19 4Q6R SIN 8.49673
20 4RW3 TDA 9.60265
21 4RW3 PLM 9.60265
22 4CCW VKC 10.4575
23 4M26 AKG 11.7647
24 6B9T 2HE 11.7647
25 3HUJ AGH 12.4183
26 3O01 DXC 15.0327
27 4LY9 S6P 15.0327
28 1LLF F23 16.3399
29 3RUG DB6 16.9935
30 1UCD U5P 19.6078
31 5K2M ADP 32.0755
Pocket No.: 4; Query (leader) PDB : 2HFN; Ligand: FMN; Similar sites found with APoc: 21
This union binding pocket(no: 4) in the query (biounit: 2hfn.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 1L0I PSR None
2 1UVC STE None
3 5K52 OCD 1.96078
4 1Q7E MET 3.26797
5 4RQL SNE 3.92157
6 2A1L PCW 3.92157
7 5L2R MLA 4.57516
8 2AWN ADP 5.22876
9 3WRB GDE 5.22876
10 4IP7 FLC 5.88235
11 6CHP F0Y 7.18954
12 4RJD TFP 7.57576
13 3WFD AXO 7.84314
14 2X34 UQ8 8.49673
15 4G86 BNT 9.80392
16 3L9R L9R 9.80392
17 6CB2 OLC 12.4183
18 6F6D AKG 13.0719
19 1ZT1 PHE GLU ALA ASN GLY ASN LEU ILE 13.0719
20 3U3U EAH 14.3791
21 4V3I ASP LEU THR ARG PRO 15.0327
Pocket No.: 5; Query (leader) PDB : 2HFN; Ligand: FMN; Similar sites found with APoc: 12
This union binding pocket(no: 5) in the query (biounit: 2hfn.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 3FEI CTM None
2 2VWA PTY None
3 1SR9 KIV 1.96078
4 2QES ADE 3.92157
5 3U6W KIV 4.57516
6 2OG7 SIN 5.88235
7 5C2H 4PX 6.53595
8 3G4Q MCH 6.84932
9 6E1Q CFA 7.84314
10 1M13 HYF 8.49673
11 3B00 16A 14.3791
12 5DJT FMN 14.7541
Pocket No.: 6; Query (leader) PDB : 2HFN; Ligand: FMN; Similar sites found with APoc: 69
This union binding pocket(no: 6) in the query (biounit: 2hfn.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
1 5H9Q TD2 None
2 4D1J DGJ None
3 1A78 TDG None
4 3E2M E2M None
5 4WUJ FMN None
6 6BOC EU7 None
7 5X80 SAL None
8 3QRC SCR 1.30719
9 1IYB 5GP 1.96078
10 5EFW FMN 2.06897
11 5FQK 6NT 2.23048
12 2P5B OGA 2.61438
13 2YBP 2HG 2.61438
14 2OS2 OGA 2.61438
15 2Q8E OGA 2.61438
16 2HZQ STR 2.61438
17 3IS2 FAD 3.26797
18 4B1M FRU FRU 3.26797
19 4Y24 TD2 3.26797
20 3B9Z CO2 3.26797
21 1SLT NDG GAL 3.73134
22 1GZW GAL BGC 3.73134
23 3OYW TDG 3.73134
24 1W6O LAT 3.73134
25 5DYO FLU 3.92157
26 4IA6 EIC 3.92157
27 5GLT BGC GAL NAG GAL 3.92157
28 3JZ0 CLY 3.92157
29 5A7V MAN 3.92157
30 5DCH 1YO 3.92157
31 5E58 CPZ 3.92157
32 5H9P TD2 3.92157
33 4UOH ADP 3.97351
34 5X7Q GLC GLC GLC GLC GLC 4.57516
35 5X7Q GLC GLC GLC GLC 4.57516
36 5LUN OGA 4.57516
37 1SGJ OAA 4.57516
38 4YLZ LAT NAG GAL 4.57516
39 1POT SPD 4.57516
40 1WW5 SGA BGC 4.57516
41 2YMZ LAT 4.61538
42 4D52 GIV 5.22876
43 4MLO PAM 5.22876
44 5EO8 TFU 5.22876
45 2VQ5 HBA 5.88235
46 5N0L ILE 5.88235
47 6A63 LAT 6.52174
48 2R0H CTO 6.53595
49 1IND EOT 6.53595
50 1ULE GLA GAL NAG 6.66667
51 3KO0 TFP 6.93069
52 2BCG GER 7.18954
53 1OH2 SUC 7.84314
54 2D6M LBT 7.84314
55 1A0T SUC 7.84314
56 5V1B 8UY 7.84314
57 1J78 OLA 8.49673
58 2YFB SIN 9.15033
59 4H69 10Y 9.15033
60 5EZU MYR 10.1124
61 4LIT AKG 10.4575
62 4KTP BGC 11.7647
63 4REI 3MV 11.9205
64 5NLD LBT 12.9496
65 4KWI 1TJ 14.3791
66 3ZO7 K6H 14.8936
67 4EXO PYR 15.7534
68 5TVF PUT 24.8366
69 3TTY GLA 39.2157
Pocket No.: 7; Query (leader) PDB : 2HFN; Ligand: FMN; Similar sites found with APoc: 11
This union binding pocket(no: 7) in the query (biounit: 2hfn.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 1SJD NPG None
2 5IF4 6AK 1.30719
3 2HFP NSI 1.96078
4 1OQC FAD 2.4
5 1GSA ADP 3.92157
6 5UWA 8ND 4.4335
7 4J25 OGA 5.22876
8 5ICE 2H4 5.88235
9 5TKL G3H 5.88235
10 3AY6 BGC 6.53595
11 3AY6 NAI 6.53595
Pocket No.: 8; Query (leader) PDB : 2HFN; Ligand: FMN; Similar sites found with APoc: 53
This union binding pocket(no: 8) in the query (biounit: 2hfn.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
1 4WGF HX2 None
2 3ZXE PGZ None
3 4N14 WR7 1.30719
4 3H9A PPY 1.30719
5 3BU1 HSM 1.35135
6 1Y0G 8PP 1.96078
7 2AGC DAO 1.96078
8 1TW4 CHD 2.4
9 5FWE OGA 2.61438
10 1ODM ASV 3.26797
11 2PCU ASP 3.26797
12 1UNB PN1 3.26797
13 3JU6 ANP 3.92157
14 5T7I LAT NAG GAL 3.92157
15 4IGQ OGA 3.92157
16 3NNF AKG 3.92157
17 4AVV CD 3.92157
18 2JIG PD2 3.92157
19 4WVW SLT 4.16667
20 3M3E GAL A2G NPO 4.57516
21 1QIN GIP 4.57516
22 5T2Z 017 5.05051
23 4WOE ADP 5.22876
24 2YG2 FLC 5.22876
25 2YG2 S1P 5.22876
26 4ORM FMN 5.22876
27 4ORM 2V6 5.22876
28 4ORM ORO 5.22876
29 2JDR L20 5.22876
30 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 5.22876
31 2BS5 BGC GAL FUC 5.55556
32 2VQ5 LDP 5.88235
33 4MA6 28E 6.53595
34 5UQD AKG 6.53595
35 6AMI TRP 7.18954
36 2OHV NHL 7.18954
37 5YB7 ORN 7.18954
38 5YB7 FAD 7.18954
39 5AIG VPR 7.2
40 3I9U DTU 7.84314
41 1BGQ RDC 8
42 2E56 MYR 9.02778
43 5KEW 6SB 9.02778
44 4QDC ASD 9.15033
45 1GQ2 OXL 9.15033
46 3KDM TES 9.33333
47 2BMR 3NT 9.80392
48 1ZPD CIT 10.4575
49 6FXR AKG 11.7647
50 1ZM1 BGC BGC BGC 11.7647
51 1NX4 AKG 15.0327
52 4OMJ 2TX 15.6863
53 1OLM VTQ 15.6863
Pocket No.: 9; Query (leader) PDB : 2HFN; Ligand: FMN; Similar sites found with APoc: 3
This union binding pocket(no: 9) in the query (biounit: 2hfn.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 2EV1 OLA 5.88235
2 5TDU PCR 6.53595
3 5OSW CIT 13.7255
Pocket No.: 10; Query (leader) PDB : 2HFN; Ligand: FMN; Similar sites found with APoc: 4
This union binding pocket(no: 10) in the query (biounit: 2hfn.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 4WQ2 3SU None
2 3TL1 JRO 5.22876
3 4YJK URA 7.18954
4 3RLF MAL 15.6863
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