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Receptor
PDB id Resolution Class Description Source Keywords
2HF9 1.9 Å EC: 7.-.-.- CRYSTAL STRUCTURE OF HYPB FROM METHANOCALDOCOCCUS JANNASCHII IN THE TRIPHOSPHATE FORM METHANOCALDOCOCCUS JANNASCHII ALPHA AND BETA PROTEIN P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE HYDROLASE METAL BINDING PROTEIN
Ref.: STRUCTURAL INSIGHTS INTO HYPB, A GTP-BINDING PROTEIN THAT REGULATES METAL BINDING. J.BIOL.CHEM. V. 281 27492 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GSP A:300;
B:300;
Valid;
Valid;
none;
none;
Kd = 3.4 uM
539.246 C10 H16 N5 O13 P3 S c1nc2...
MG A:301;
B:301;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
ZN A:302;
B:302;
Part of Protein;
Part of Protein;
none;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2HF9 1.9 Å EC: 7.-.-.- CRYSTAL STRUCTURE OF HYPB FROM METHANOCALDOCOCCUS JANNASCHII IN THE TRIPHOSPHATE FORM METHANOCALDOCOCCUS JANNASCHII ALPHA AND BETA PROTEIN P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE HYDROLASE METAL BINDING PROTEIN
Ref.: STRUCTURAL INSIGHTS INTO HYPB, A GTP-BINDING PROTEIN THAT REGULATES METAL BINDING. J.BIOL.CHEM. V. 281 27492 2006
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 293 families.
1 2HF8 Kd = 3.4 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
2 2HF9 Kd = 3.4 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 250 families.
1 2HF8 Kd = 3.4 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
2 2HF9 Kd = 3.4 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 204 families.
1 2HF8 Kd = 3.4 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
2 2HF9 Kd = 3.4 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GSP; Similar ligands found: 139
No: Ligand ECFP6 Tc MDL keys Tc
1 GSP 1 1
2 GP3 0.897436 0.925
3 GTP 0.853659 0.948718
4 GNH 0.829268 0.936709
5 GDP 0.817073 0.948718
6 G1R 0.8 0.936709
7 GCP 0.77907 0.925
8 GNP 0.770115 0.925
9 9GM 0.770115 0.925
10 GMV 0.767442 0.925
11 G 0.756098 0.935897
12 5GP 0.756098 0.935897
13 G2R 0.747253 0.91358
14 GDD 0.744681 0.91358
15 GDC 0.744681 0.91358
16 GKE 0.744681 0.91358
17 GPG 0.73913 0.91358
18 GTG 0.736842 0.891566
19 G3A 0.729167 0.925
20 G5P 0.721649 0.925
21 GDR 0.71875 0.91358
22 GFB 0.71875 0.91358
23 GAV 0.714286 0.987179
24 GP2 0.712644 0.91358
25 6CK 0.71134 0.891566
26 Y9Z 0.708333 0.860465
27 JB2 0.69697 0.91358
28 GKD 0.69697 0.91358
29 G2P 0.692308 0.91358
30 GDX 0.69 0.925
31 GPD 0.69 0.880952
32 ALF 5GP 0.67033 0.847059
33 0O2 0.666667 0.935897
34 YGP 0.663265 0.858824
35 JB3 0.657143 0.902439
36 GDP ALF 0.645833 0.847059
37 GDP AF3 0.645833 0.847059
38 ALF GDP 0.645833 0.847059
39 GMP 0.641975 0.835443
40 G3D 0.638298 0.935897
41 NGD 0.635514 0.91358
42 2MD 0.633027 0.894118
43 CAG 0.630631 0.840909
44 G4P 0.625 0.935897
45 FEG 0.62037 0.83908
46 U2G 0.62037 0.891566
47 G G 0.617647 0.901235
48 MGD 0.616071 0.894118
49 ZGP 0.614679 0.872093
50 CG2 0.609091 0.891566
51 TPG 0.598291 0.804348
52 3GP 0.595506 0.898734
53 GDP 7MG 0.590476 0.86747
54 GH3 0.581633 0.924051
55 PGD 0.581197 0.926829
56 MD1 0.581197 0.894118
57 2GP 0.577778 0.911392
58 GCP G 0.563107 0.875
59 DGT 0.561224 0.878049
60 DBG 0.558333 0.902439
61 G1G 0.550847 0.880952
62 AGS 0.547368 0.924051
63 SAP 0.547368 0.924051
64 FE9 0.546219 0.8
65 A G 0.543103 0.888889
66 G4M 0.539062 0.840909
67 U A G G 0.538462 0.888889
68 G A A A 0.529915 0.878049
69 MGP 0.525253 0.91358
70 GPX 0.524272 0.898734
71 BGO 0.521739 0.879518
72 DGI 0.520408 0.878049
73 6G0 0.52 0.91358
74 IDP 0.515464 0.923077
75 R7I 0.51 0.898734
76 R5I 0.51 0.898734
77 GGM 0.508475 0.858824
78 G1R G1R 0.508065 0.879518
79 PGD O 0.504 0.875
80 AKW 0.495726 0.915663
81 G U 0.491525 0.857143
82 GTA 0.486726 0.891566
83 P2G 0.484536 0.839506
84 GPC 0.483607 0.83908
85 G C 0.483333 0.857143
86 P1G 0.474747 0.829268
87 DG 0.474227 0.865854
88 DGP 0.474227 0.865854
89 BA3 0.46875 0.85
90 IMP 0.463918 0.910256
91 B4P 0.463918 0.85
92 AP5 0.463918 0.85
93 G2Q 0.462963 0.91358
94 G G G RPC 0.459016 0.833333
95 APC G U 0.456 0.843373
96 ATP 0.45 0.873418
97 HEJ 0.45 0.873418
98 G G G C 0.448819 0.869048
99 A2D 0.447917 0.85
100 5FA 0.445545 0.873418
101 AQP 0.445545 0.873418
102 A G C C 0.445312 0.86747
103 G7M 0.444444 0.901235
104 G U34 0.442623 0.847059
105 01G 0.442478 0.860465
106 ITT 0.44 0.825
107 SGP 0.44 0.876543
108 HFD 0.436893 0.831325
109 G C C C 0.431818 0.879518
110 AT4 0.43 0.911392
111 AN2 0.43 0.8625
112 DG DG 0.428571 0.825581
113 A4P 0.42623 0.829545
114 UCG 0.424242 0.86747
115 PCG 0.423077 0.886076
116 C2E 0.423077 0.875
117 35G 0.423077 0.886076
118 MGO 0.420561 0.823529
119 ADP 0.42 0.873418
120 ANP 0.419048 0.851852
121 5GP 5GP 0.419048 0.839506
122 ADQ 0.418182 0.829268
123 7DT 0.417476 0.860759
124 AR6 0.417476 0.85
125 APR 0.417476 0.85
126 PRT 0.417391 0.910256
127 C1Z 0.415929 0.935897
128 A G U 0.414286 0.847059
129 AD9 0.413462 0.851852
130 UP5 0.413223 0.831325
131 A22 0.412844 0.8625
132 25L 0.412281 0.8625
133 M33 0.411765 0.839506
134 JBT 0.410405 0.783505
135 ACP 0.407767 0.851852
136 6YZ 0.407407 0.851852
137 ACQ 0.40566 0.851852
138 A1R 0.405405 0.8
139 A G U U 0.4 0.847059
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2HF9; Ligand: GSP; Similar sites found with APoc: 636
This union binding pocket(no: 1) in the query (biounit: 2hf9.bio2) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 1R4A GNP None
2 1VG8 GNP None
3 1VG1 GDP None
4 3AQ4 GDP None
5 1EK0 GNP None
6 2C3H GLC GLC None
7 2CJU PHX None
8 4WOP CTP 0.888889
9 2OFW ADX 0.961538
10 2QG6 NMN 1.00503
11 2PEZ GGZ 1.11732
12 2PEZ DAT 1.11732
13 1BO4 COA 1.19048
14 4DDY DN6 1.32743
15 5KSP GDP 1.57895
16 1ION ADP 1.76991
17 5XQL C2E 1.76991
18 1KY3 GDP 2.1978
19 1FZQ GDP 2.20994
20 2VVG ADP 2.21239
21 1XP8 AGS 2.21239
22 2IXE ATP 2.21239
23 3DZD ADP 2.21239
24 5EE5 GTP 2.34742
25 1M7G ADX 2.36967
26 1M7G ADP 2.36967
27 1M7G AV2 2.36967
28 3QXC ATP 2.47934
29 1VG0 GDP 2.65487
30 1VG9 GDP 2.65487
31 5W75 GDP 2.65487
32 2WKQ GTP 2.65487
33 3DKP ADP 2.65487
34 2ZR9 DTP 2.65487
35 4KBF AMP 2.65487
36 3TBK ANP 2.65487
37 1U0J ADP 2.65487
38 4KVL PLM 2.65487
39 4WEI GLC GAL 2.65487
40 5I0H ADP BEF 2.65487
41 3RC3 ANP 2.65487
42 4IOK XPO 2.65487
43 5X40 ACP 2.65487
44 3THR C2F 2.65487
45 2Z9I GLY ALA THR VAL 2.65487
46 3BOS CDP 2.65487
47 1D2N ANP 2.65487
48 5ZI9 FLC 2.65487
49 4IOK ADP 2.65487
50 3SBD GNP 2.6738
51 2WCU FUC 2.68456
52 1Y63 ADP 2.71739
53 4TTQ ATP 2.7907
54 1Z0A GDP 2.87356
55 3MWL 8OX 2.89855
56 1G16 GDP 2.94118
57 2O66 FLC 2.96296
58 4U00 ADP 3.09735
59 5GVR LMR 3.09735
60 1D2E GDP 3.09735
61 4IHQ ADP 3.09735
62 1G7S GDP 3.09735
63 5KSZ GCP 3.09735
64 4YJ1 ADP 3.09735
65 3Q9L ATP 3.09735
66 2BEK ATP 3.09735
67 4V03 ADP 3.09735
68 2CHG ANP 3.09735
69 2NCD ADP 3.09735
70 2OZE AGS 3.09735
71 4PJ3 ANP 3.09735
72 1OYY AGS 3.09735
73 4QOS ADP 3.09735
74 1OIX GDP 3.14136
75 3GJ0 GDP 3.16742
76 3GJ3 GDP 3.16742
77 3CH5 GDP 3.24074
78 6AIC AMP 3.27103
79 4YLG GDP 3.46821
80 2CDN ADP 3.48259
81 2HV8 GTP 3.48837
82 2PZE ATP 3.53982
83 1G6H ADP 3.53982
84 4PPF FLC 3.53982
85 5YV5 ADP 3.53982
86 5W76 GDP 3.53982
87 3EZ2 ADP 3.53982
88 2D2F ADP 3.53982
89 2FJU GSP 3.53982
90 3FXU TSU 3.53982
91 5FHD ADP ALF 3.53982
92 2ZFI ADP 3.53982
93 5FTB ANP 3.53982
94 1CR1 TTP 3.53982
95 3BER AMP 3.53982
96 1VKJ A3P 3.53982
97 3HU3 AGS 3.53982
98 3VX3 ADP 3.53982
99 3G5S GSH 3.53982
100 4NU0 AP5 3.68664
101 2BCG GDP 3.8835
102 1TKU 5RP 3.92157
103 3E5H GNP 3.93258
104 2AWN ADP 3.9823
105 1JJ7 ADP 3.9823
106 1RRC ADP 3.9823
107 1WA5 GTP 3.9823
108 2C77 GNP 3.9823
109 2C78 GNP 3.9823
110 1SKQ GDP 3.9823
111 4ZKD GDP 3.9823
112 1MKY GDP 3.9823
113 5FG3 GDP 3.9823
114 4IEE AGS 3.9823
115 4LYA ATP 3.9823
116 3ZS9 ADP ALF 3.9823
117 3B7G ANP 3.9823
118 2WOJ ADP ALF 3.9823
119 4XTR ATP 3.9823
120 4XVU ATP 3.9823
121 1IWE IMP 3.9823
122 3ZFD ANP 3.9823
123 5ZBR ANP 3.9823
124 4XTR ADP 3.9823
125 2CE7 ADP 3.9823
126 6B4K ANP 3.9823
127 1L2T ATP 3.9823
128 5U32 GDP 3.9823
129 2Q2Y MKR 3.9823
130 2Q2Y ADP 3.9823
131 1Z08 GNP 4.11765
132 3TMK T5A 4.16667
133 1KAO GDP 4.19162
134 5BQ5 ADP BEF 4.2328
135 1KSH GDP 4.30108
136 1YZN GNP 4.32432
137 1GWN GTP 4.39024
138 4YMU ATP 4.42478
139 2BVN GNP 4.42478
140 5W7Q GDP 4.42478
141 1D8T GDP 4.42478
142 5LB3 ADP 4.42478
143 1QF5 RPL 4.42478
144 1QF5 GDP 4.42478
145 1P9B GDP 4.42478
146 5H4S RAM 4.42478
147 3IUY AMP 4.42478
148 2J5V PCA 4.42478
149 1G41 ADP 4.42478
150 5I34 GDP 4.42478
151 2QEN ADP 4.42478
152 4GBM A3P 4.42478
153 2VWT PYR 4.42478
154 4TL6 ANP 4.42478
155 1Z0F GDP 4.46927
156 1X1R GDP 4.49438
157 3UIE ANP 4.5
158 4D0G GTP 4.57143
159 3TNF GNP 4.5977
160 4LHW GNP 4.5977
161 1ZIN AP5 4.60829
162 2CJW GDP 4.6875
163 3Q72 GNP 4.81928
164 4NTO 1PW 4.83092
165 1BG2 ADP 4.86726
166 3CX8 GSP 4.86726
167 1ZCB GDP 4.86726
168 3AB3 GDP 4.86726
169 3VMF GTP 4.86726
170 3CNL GNP 4.86726
171 1WDT GTP 4.86726
172 5MZN ADP 4.86726
173 4R43 GDP 4.86726
174 4NE2 SH2 4.86726
175 4NE2 ADP 4.86726
176 5G3Y ADP 4.86726
177 1V8K ANP 4.86726
178 5IFS ADP 4.86726
179 5WC2 ADP 4.86726
180 1YTM ATP 4.86726
181 5UIV ADP 4.86726
182 1SQ5 ADP 4.86726
183 3RLF ANP 4.86726
184 5M7P ADP 4.86726
185 1NJF AGS 4.86726
186 1OS1 PYR 4.86726
187 1NJF ADP 4.86726
188 1OS1 ATP 4.86726
189 4OHY ANP 4.86726
190 1SVM ATP 4.86726
191 2IS6 ADP 4.86726
192 1M7B GTP 4.8913
193 3N5C GDP 4.93827
194 3ZQ6 ADP ALF 4.93827
195 1MR3 G3D 4.97238
196 3IIJ ADP 5
197 2F9L GDP 5.02513
198 4BAS GNP 5.02513
199 1S3G AP5 5.06912
200 4OI4 ATP 5.21739
201 1OIV GDP 5.2356
202 5KUT GDP 5.29101
203 4WZ6 ATP 5.30973
204 1SVK ALF GDP 5.30973
205 1BH2 GSP 5.30973
206 1TAD GDP 5.30973
207 1TAD ALF 5.30973
208 6AU6 GDP 5.30973
209 2OM2 GDP 5.30973
210 1FQJ GDP 5.30973
211 1B0U ATP 5.30973
212 3B5J 12D 5.30973
213 1Y3A GDP 5.30973
214 1FQK GDP 5.30973
215 1DAR GDP 5.30973
216 4DCT GDP 5.30973
217 5M04 GDP 5.30973
218 5IRR GSP 5.30973
219 4A4Z ANP 5.30973
220 5Z69 AGS 5.30973
221 1FQJ ALF 5.30973
222 1FQK ALF 5.30973
223 2J0W ASP 5.30973
224 4ZDJ UTP 5.30973
225 2ZJ5 ADP 5.30973
226 2B8W ALF 5GP 5.30973
227 1K6M AGS 5.30973
228 1F5N GNP 5.30973
229 5IRN ADP 5.30973
230 4X1Z FUC GAL NDG 5.30973
231 3H4S ADP 5.30973
232 2Z5F A3P 5.30973
233 4FRZ ADP 5.30973
234 1LVK MNT BEF 5.30973
235 1CS4 GSP 5.33333
236 5YT0 GDP 5.49451
237 5N69 ADP 5.52764
238 4MKF AP5 5.52995
239 5JCZ GDP 5.58659
240 2ZX2 RAM 5.64103
241 3NJQ NJQ 5.69948
242 4RD0 GDP 5.75221
243 5JBQ GDP 5.75221
244 4G5G GDP 5.75221
245 3U6K GDP 5.75221
246 3U6B GDP 5.75221
247 4P3Y GDP 5.75221
248 3MD0 GDP 5.75221
249 4HSE ADP 5.75221
250 4XGU ADP 5.75221
251 3KJI ADP 5.75221
252 4GOX A3P 5.75221
253 1IN4 ADP 5.75221
254 6FAA ADP 5.75221
255 1FP6 ADP 5.75221
256 2ZTS ADP 5.75221
257 4E03 ADP 5.82524
258 3RAB GNP 5.91716
259 3Q85 GNP 5.91716
260 1T5C ADP 6.19469
261 2XT3 ADP 6.19469
262 2QTV GNP 6.19469
263 4YDS ATP 6.19469
264 2ODE ALF GDP 6.19469
265 3GJX GTP 6.19469
266 4AG5 ADP 6.19469
267 3PCR GTP 6.19469
268 4PC3 GDP 6.19469
269 3VM7 GLC 6.19469
270 2CK3 ADP 6.19469
271 1XKV ATP 6.19469
272 3R7F CP 6.19469
273 6B8B ADP 6.19469
274 2V7Q ADP 6.19469
275 3A4M ADP 6.19469
276 1W0J ADP BEF 6.19469
277 2CK3 ANP 6.19469
278 3COB ADP 6.19469
279 1W0J ADP 6.19469
280 2V7Q ATP 6.19469
281 1NRJ GTP 6.32911
282 5OCG GNP 6.34921
283 2GJ8 ALF GDP 6.39535
284 3QBT GNP 6.42857
285 1NN5 ANP 6.51163
286 1NN5 2DT 6.51163
287 5ZB0 TYD 6.56566
288 5ZB0 ADP 6.56566
289 4M9Q GNP 6.63717
290 1WF3 GNP 6.63717
291 5GOE GDP 6.63717
292 1XMV ADP 6.63717
293 5VGR GDP 6.63717
294 3DEF GDP 6.63717
295 5VHC BEF ADP 6.63717
296 1W5T ADP 6.63717
297 4TQK NAG 6.63717
298 3QDK QDK 6.63717
299 1W5T ANP 6.63717
300 3FYH ADP 6.63717
301 4RLQ 3SK 6.63717
302 2GDJ ANP 6.63717
303 2YOH WMJ 6.66667
304 1DS6 GDP 6.77083
305 1KO8 6PG 6.85714
306 5UQW GDP 6.87831
307 6FA4 GNP 6.93642
308 2EW1 GNP 6.96517
309 1MH1 GNP 6.98925
310 2KIN ADP 7
311 1G4U GDP 7.06522
312 4JLV ADP 7.07965
313 4TMZ GSP 7.07965
314 1PUJ GNP 7.07965
315 4NCN GTP 7.07965
316 6G14 G4P 7.07965
317 1IHU ADP 7.07965
318 3FVQ ATP 7.07965
319 2X7I CIT 7.07965
320 1IHU AF3 7.07965
321 2VB6 ADP BEF 7.07965
322 4PFO ADP 7.07965
323 5E95 GDP 7.14286
324 1XEX ATP 7.14286
325 2D7C GTP 7.18563
326 3REF GDP 7.2165
327 1CLU DBG 7.22892
328 1WQ1 GDP 7.22892
329 1WQ1 AF3 7.22892
330 5Z2M GTP 7.24638
331 1XX6 ADP 7.32984
332 1VHT BA3 7.33945
333 1HE1 GDP 7.40741
334 2WJG GDP 7.44681
335 3LRE ADP 7.52212
336 5JCP GDP ALF 7.52212
337 5H7K GDP 7.52212
338 1G6O ADP 7.52212
339 1QHH ATP 7.52212
340 5K5Z ANP 7.52212
341 1QHG ATP 7.52212
342 2ZE7 DST 7.52212
343 1R0X ATP 7.52212
344 1GVF PGH 7.52212
345 3CV2 OXL 7.52212
346 4KFU ACP 7.54717
347 5DI3 GNP 7.56757
348 1YVD GNP 7.69231
349 1QF9 C5P 7.73196
350 1QF9 ALF 7.73196
351 1QF9 ADP 7.73196
352 1YZG GDP 7.82123
353 5WLB GNP 7.83133
354 2UZI GTP 7.83133
355 1E96 GTP 7.88177
356 4CVN ADP 7.9646
357 3WYA GDP 7.9646
358 3WXM GTP 7.9646
359 3WY9 GDP 7.9646
360 2DPY ADP 7.9646
361 2OBM ADP 7.9646
362 1G7C 5GP 7.9646
363 5L3V GDP 7.9646
364 4KVA GTP 7.9646
365 1UJ2 C5P 7.9646
366 1UJ2 ADP 7.9646
367 4RZ3 ADP 7.9646
368 1ZD9 GDP 7.97872
369 1DAK ADP 8.03571
370 1DAK DPU 8.03571
371 3GJ8 GDP 8.1448
372 3GJ5 GDP 8.1448
373 4QM7 GTP 8.18713
374 1JJV ATP 8.25243
375 4KAX GTP 8.28402
376 3FKQ ATP 8.31099
377 1ZUI SKM 8.33333
378 2XTZ GSP 8.40708
379 2WHX ADP 8.40708
380 4Q1A UDP 8.40708
381 4Q1A 2XZ 8.40708
382 2JLR ANP 8.40708
383 1G3Q ADP 8.40708
384 5E58 CPZ 8.40708
385 1OE0 TTP 8.40708
386 6A20 ADP 8.40708
387 1M2O GNP 8.42105
388 1O3Y GTP 8.43373
389 2J59 GTP 8.43373
390 1J2J GTP 8.43373
391 2GCO GNP 8.45771
392 2GCN GDP 8.45771
393 3CPJ GDP 8.52018
394 5G41 AP5 8.52018
395 5H67 ATP 8.54271
396 1AKY AP5 8.63636
397 2RGX AP5 8.73786
398 4MKG AP5 8.75576
399 1OW3 GDP 8.80829
400 1IBR GNP 8.84956
401 4LX0 BEF GDP 8.84956
402 2G77 GDP 8.84956
403 1YRB GDP 8.84956
404 3IO3 ADP 8.84956
405 2G77 AF3 8.84956
406 4ZG4 VO4 ADP 8.84956
407 1UKZ ADP 8.86699
408 2W2X GSP 8.87097
409 1LFD GNP 8.98204
410 5OEC GDP 9.13706
411 6BC0 GSP 9.18919
412 6BCB GSP 9.18919
413 6BCA GSP 9.18919
414 4D0N GDP 9.18919
415 3LXR GDP 9.18919
416 5HPY GDP 9.18919
417 3BC1 GNP 9.23077
418 1SVI GDP 9.23077
419 1KMQ GNP 9.23913
420 2C5L GTP 9.24856
421 3KTA AP5 9.24856
422 3FB4 AP5 9.25926
423 3WYG GTP 9.29204
424 5UWH GNP 9.29204
425 5UWT GNP 9.29204
426 3M1I GTP 9.29204
427 5UWU GNP 9.29204
428 3WYF GTP 9.29204
429 5UWJ GNP 9.29204
430 5UWI GNP 9.29204
431 5UWS GNP 9.29204
432 5UWP GNP 9.29204
433 5DIF GNP 9.29204
434 5UWR GNP 9.29204
435 5UWO GNP 9.29204
436 5DHF GNP 9.29204
437 5UWQ GNP 9.29204
438 6CIT GNP 9.29204
439 5UWW GNP 9.29204
440 4HAT GNP 9.29204
441 2WIC GNP 9.29204
442 5DI9 GNP 9.29204
443 4NON GDP 9.29204
444 1YQT ADP 9.29204
445 3NHB ADP 9.29204
446 4J0Q GDP 9.29204
447 4GOJ GNP 9.29204
448 3T34 GDP 9.29204
449 4R98 GNH 9.29204
450 1FNN ADP 9.29204
451 1CXZ GSP 9.34066
452 4X8O AP5 9.34579
453 3LN9 FLC 9.35252
454 4K81 GTP 9.35672
455 4XSH GSP 9.49721
456 3X1Z GNP 9.58084
457 4HDO GNP 9.58084
458 4HDQ GNP 9.58084
459 1F6B GDP 9.59596
460 1TX4 ALF GDP 9.60452
461 3TKL GTP 9.69388
462 2GKS ADP 9.73451
463 1JI0 ATP 9.73451
464 6DEF GCP 9.73451
465 2D7D ADP 9.73451
466 4IDN GNP 9.73451
467 6H5E ANP 9.73451
468 5O74 GDP 10
469 4KVG GTP 10.119
470 5CK5 GDP 10.177
471 1OXV ANP 10.177
472 4PX9 ADP 10.177
473 3A1S GDP 10.177
474 5XDR ADP 10.177
475 5AK0 8V1 10.177
476 3FWY ADP 10.177
477 2CBZ ATP 10.177
478 2BME GNP 10.2151
479 4BQS K2Q 10.2273
480 4BQS ADP 10.2273
481 2FH5 GTP 10.2703
482 3NKV GNP 10.2857
483 1RYH GNP 10.3448
484 1RE0 GDP 10.4072
485 2A5J GDP 10.4712
486 3SFV GDP 10.4972
487 1GOJ ADP 10.6195
488 1F9V ADP 10.6195
489 4P4T GDP 10.6195
490 4FCW ADP 10.6195
491 5LTJ ADP 10.6195
492 1W7J ADP BEF 10.6195
493 3ITJ CIT 10.6195
494 5LTJ BEF 10.6195
495 1R6B ADP 10.6195
496 3HQP OXL 10.6195
497 6BSX GDP 10.6742
498 6BSX E7S 10.6742
499 3W5J GDP 10.7843
500 2WJH GDP 10.8434
501 2WJH FLC 10.8434
502 2A5F GTP 10.8571
503 3ZIA ADP 10.8696
504 3ZIA ATP 10.8696
505 1B7T ADP 10.8974
506 1OFH ADP 10.9195
507 5IRC GDP 10.9453
508 1Z0K GTP 11.0465
509 4XOI GTP 11.0619
510 5J1J ANP 11.0619
511 1Z6T ADP 11.0619
512 3T12 GDP ALF 11.1111
513 3T1O GDP 11.1111
514 2A9K GDP 11.2299
515 2C9O ADP 11.5044
516 3DOE GTP 11.5152
517 1LVG ADP 11.6162
518 1Z0J GTP 11.8644
519 5UPK GNP 11.9469
520 4DID GDP 11.9469
521 2QZ4 ADP 11.9469
522 1X6V ADP 11.9469
523 4BFW ZVW 11.9469
524 2ZEJ GDP 11.9565
525 1UAD GNP 12
526 1ZC3 GNP 12
527 4ZI2 GNP 12.0301
528 1Z06 GNP 12.1693
529 1KK8 BEF ADP 12.2302
530 3DDC GNP 12.2699
531 5EXT ADP 12.3077
532 2RCN GDP 12.3894
533 5ZXD ATP 12.3894
534 4B47 GDP 12.3894
535 5HR5 ADP 12.3894
536 5LLB 6YZ 12.3894
537 3RWO GDP 12.4324
538 1U8Z GDP 12.5
539 2J0V GDP 12.7358
540 2VOH CIT 12.7389
541 2EFE GNH 12.8319
542 2PL3 ADP 12.8319
543 3EC1 GDP 12.8319
544 4D81 ADP 12.8319
545 2FAH GDP 12.8319
546 3T5G GDP 13.2597
547 6BVJ GNP 13.2743
548 6D5M GNP 13.2743
549 6D56 GNP 13.2743
550 6D5E GNP 13.2743
551 6D59 GNP 13.2743
552 6BVL GNP 13.2743
553 6D5J GNP 13.2743
554 6BVK GNP 13.2743
555 6D5H GNP 13.2743
556 6D5V GNP 13.2743
557 6BVI GNP 13.2743
558 6D55 GNP 13.2743
559 6D5G GNP 13.2743
560 6BVM GNP 13.2743
561 6D5L GNP 13.2743
562 1NVV GNP 13.2743
563 4LC1 GDP 13.2743
564 5WDR GNP 13.4503
565 2XTN GTP 13.7168
566 5SZH GNP 13.7255
567 1Z83 AP5 13.7755
568 1S9D GDP 13.7931
569 4QRH 0O2 13.8095
570 1NF3 GNP 13.8462
571 2QN6 GDP 13.9785
572 1GRN GDP 14.1361
573 4ITR GDP 14.1361
574 1A4R GDP 14.1361
575 1A4R GNH 14.1361
576 2NGR GDP 14.1361
577 2NGR AF3 14.1361
578 5H7J GCP 14.1593
579 2WMO GTP 14.2105
580 2W83 GTP 14.2857
581 3PQC GDP 14.359
582 2IYL GDP 14.4366
583 1KK1 GNP 14.6018
584 4H1V GNP 14.6018
585 1S8F GDP 14.6893
586 3EWA ANP 14.9068
587 4YC7 GNP 14.9171
588 4LJ9 ACP 15.0442
589 3TK1 GDP 15.4867
590 1R2Q GNP 15.8824
591 5BN3 ADP 15.9292
592 1ZJ6 G3D 16.0428
593 3MJH GTP 16.0714
594 2HCJ GDP 16.2162
595 2GK6 ADP 16.3717
596 1RJ9 GCP 16.3717
597 3KC1 2T6 16.3717
598 5BXQ GDP 16.5354
599 1I4D GDP 16.9643
600 5HCN GCP 17.6991
601 1Z2A GDP 17.8571
602 3GJ4 GDP 18.1818
603 2HT6 GDP 18.3908
604 5E5U MLI 18.5841
605 5MVR ADP 19.1358
606 6C90 ADP 19.2308
607 2Y65 ADP 19.469
608 6CS8 F9Y 19.9115
609 5KDO GDP 20.2703
610 4WZA ACP 20.354
611 4WZA ADP 20.354
612 1GOT GDP 20.5479
613 1NY5 ADP 21.2389
614 3GJ7 GDP 21.4286
615 1HTW ADP 22.1519
616 3B9Q MLI 23.0089
617 2OG2 MLI 23.0089
618 5L3R GCP 23.0089
619 1GUA GNP 23.9521
620 4U5X GNP 24.7191
621 3E70 GDP 26.9911
622 3KUD GDP 27.1605
623 3QF7 ANP 28
624 4DKX GDP 28.7611
625 2XAU ADP 28.7611
626 4C4P GNP 28.972
627 5L3S GNP 30.0885
628 5L3W GDP 30.0885
629 5XC5 GTP 30.1136
630 2X77 GDP 32.8042
631 6CRK GDP 33.8028
632 1GP2 GDP 33.8028
633 5LEF GTP 34.0314
634 2Y8E GNP 35.7542
635 2FFQ GSP 38.5965
636 1YZQ GNP 42.3529
Pocket No.: 2; Query (leader) PDB : 2HF9; Ligand: GSP; Similar sites found with APoc: 13
This union binding pocket(no: 2) in the query (biounit: 2hf9.bio2) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 5FJJ MAN 3.53982
2 6BYF CIT 4.11765
3 2P3V SRT 4.42478
4 4Z7X 3CX 4.42478
5 5AHO TLA 4.86726
6 1YXM ADE 6.19469
7 2BIF ANP 6.63717
8 2BIF SIN 6.63717
9 1HE1 AF3 7.40741
10 2ZPA ADP 9.29204
11 4UP4 NDG 9.29204
12 4UP4 NAG 9.29204
13 5L3S G 30.0885
Pocket No.: 3; Query (leader) PDB : 2HF9; Ligand: GSP; Similar sites found with APoc: 57
This union binding pocket(no: 3) in the query (biounit: 2hf9.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 4DE2 DN3 1.32743
2 3BY8 MLT 1.40845
3 1U3G ADP 2.6455
4 5WRI A3P 2.65487
5 3BFX A3P 2.65487
6 1XCL SAH 2.65487
7 5WRJ A3P 2.65487
8 3WLV AZA 2.65487
9 5J1S ATP 3.09735
10 5H68 AGS 3.09735
11 2R0D 4IP 3.09735
12 3B8I OXL 3.09735
13 5XJD 87L 3.18182
14 3GUZ PAF 3.40909
15 5EP2 AZU 3.53982
16 1WMA AB3 3.53982
17 1WMA NDP 3.53982
18 1B4U DHB 3.59712
19 3QVV A3P 3.9823
20 1E2K TMC 3.9823
21 3EF0 ALF 3.9823
22 5MB4 NAG 3.9823
23 3MBI HSX 3.9823
24 3QKT ANP 3.9823
25 2W5P CL8 4.02685
26 3H86 AP5 4.6875
27 2BO4 FLC 4.86726
28 2WPB ZZI 4.86726
29 3QDW A2G 4.8951
30 3QDX A2G GAL 4.8951
31 3QDT A2G GAL 4.8951
32 3QDY A2G GAL 4.8951
33 3BIB PSF 5.17241
34 5WQP NCA 5.30973
35 5E8J SAH 5.30973
36 2VHJ ADP 5.75221
37 1G8S MET 6.19469
38 3P7I P7I 6.19469
39 1XPJ TLA 6.34921
40 1G4U AF3 7.06522
41 2FNA ADP 7.52212
42 2X2T GAL NGA 7.84314
43 2FJK 13P 7.9646
44 4KAX 4IP 8.28402
45 1P72 ADP 8.40708
46 3N9R TD3 8.40708
47 4JLS 3ZE 8.55263
48 3BRE C2E 9.29204
49 4UP4 GAL NAG 9.29204
50 5W7B MYR 11.3475
51 1GQY ACP 11.5044
52 2Q8M AMP 11.9469
53 1AQU A3P 12.3894
54 3A3B FMN 13.1579
55 2ILZ GTP 16.8142
56 5E5U MLT 18.5841
57 1T36 ORN 19.469
Pocket No.: 4; Query (leader) PDB : 2HF9; Ligand: GSP; Similar sites found with APoc: 18
This union binding pocket(no: 4) in the query (biounit: 2hf9.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 4RJD TFP None
2 2J9L ATP None
3 1ZEI CRS None
4 2DUR MAN MAN 1.76991
5 2WZF BGC 2.65487
6 1FWV SGA MAG FUC 3.73134
7 3BY9 SIN 3.9823
8 2JBM SRT 4.42478
9 5EQ8 HSO 4.42478
10 3QDV A2G 4.8951
11 2OFD NGA 5.6338
12 2XZ9 PYR 5.75221
13 1P3D ANP 7.07965
14 4GN8 ASO 8.84956
15 1L5J TRA 9.29204
16 3PUN FUC GAL NDG FUC 11.5044
17 1U9L ASN ARG PRO ILE LEU SER LEU 12.8571
18 2E1A MSE 17.3333
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