Receptor
PDB id Resolution Class Description Source Keywords
2H88 1.74 Å EC: 1.3.5.1 AVIAN MITOCHONDRIAL RESPIRATORY COMPLEX II AT 1.8 ANGSTROM R GALLUS GALLUS COMPLEX II MEMBRANE PROTEIN HEME PROTEIN IRON SULFUR PROTCYTOCHROME B OXIDOREDUCTASE REDOX ENZYME RESPIRATORY CHAOXALOACETATE UBIQUINONE
Ref.: CRYSTALLOGRAPHIC STUDIES OF THE BINDING OF LIGANDS DICARBOXYLATE SITE OF COMPLEX II, AND THE IDENTITY LIGAND IN THE BIOCHIM.BIOPHYS.ACTA V.1757 1073
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
AZI A:623;
N:623;
Invalid;
Invalid;
none;
none;
submit data
42.02 N3 [N-]=...
BHG C:141;
P:205;
Invalid;
Invalid;
none;
none;
submit data
264.315 C12 H24 O6 CCCCC...
F3S B:1004;
O:1004;
Part of Protein;
Part of Protein;
none;
none;
submit data
295.795 Fe3 S4 S1[Fe...
FAD A:1001;
N:1001;
Invalid;
Invalid;
none;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
FES B:1002;
O:1002;
Part of Protein;
Part of Protein;
none;
none;
submit data
175.82 Fe2 S2 S1[Fe...
GOL B:1009;
O:1009;
Invalid;
Invalid;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
HEM C:142;
P:201;
Part of Protein;
Part of Protein;
none;
none;
submit data
616.487 C34 H32 Fe N4 O4 Cc1c2...
K A:622;
B:253;
N:622;
O:253;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
39.098 K [K+]
SF4 B:1003;
O:1003;
Part of Protein;
Part of Protein;
none;
none;
submit data
351.64 Fe4 S4 [S]12...
TEO A:1002;
N:1002;
Valid;
Valid;
none;
none;
submit data
132.072 C4 H4 O5 C(=C(...
UNL A:1003;
A:1004;
A:1005;
A:1006;
A:1007;
A:1008;
B:1007;
B:1008;
C:143;
C:144;
C:145;
C:146;
C:147;
C:148;
C:149;
C:237;
C:238;
D:107;
D:108;
D:114;
D:116;
D:119;
D:249;
D:250;
D:251;
D:252;
D:253;
D:254;
N:1003;
N:1004;
N:1005;
N:1006;
N:1007;
N:1008;
N:1009;
N:1010;
N:1011;
N:1012;
O:1007;
O:1008;
P:208;
P:209;
P:214;
P:215;
P:216;
P:217;
P:220;
P:229;
P:230;
P:231;
P:232;
P:240;
P:241;
P:242;
Q:212;
Q:213;
Q:218;
Q:219;
Q:228;
Q:256;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
n/a NULL NULL
UNL UNL B:1005;
O:1005;
Invalid;
Invalid;
none;
none;
submit data n/a n/a n/a n/a
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2H88 1.74 Å EC: 1.3.5.1 AVIAN MITOCHONDRIAL RESPIRATORY COMPLEX II AT 1.8 ANGSTROM R GALLUS GALLUS COMPLEX II MEMBRANE PROTEIN HEME PROTEIN IRON SULFUR PROTCYTOCHROME B OXIDOREDUCTASE REDOX ENZYME RESPIRATORY CHAOXALOACETATE UBIQUINONE
Ref.: CRYSTALLOGRAPHIC STUDIES OF THE BINDING OF LIGANDS DICARBOXYLATE SITE OF COMPLEX II, AND THE IDENTITY LIGAND IN THE BIOCHIM.BIOPHYS.ACTA V.1757 1073
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1YQ3 - TEO C4 H4 O5 C(=C(O)/[O....
2 2H89 - MLI C3 H2 O4 C(C(=O)[O-....
3 2H88 - TEO C4 H4 O5 C(=C(O)/[O....
4 2FBW - CBE C12 H13 N O2 S CC1=C(SCCO....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1YQ3 - TEO C4 H4 O5 C(=C(O)/[O....
2 2H89 - MLI C3 H2 O4 C(C(=O)[O-....
3 2H88 - TEO C4 H4 O5 C(=C(O)/[O....
4 2FBW - CBE C12 H13 N O2 S CC1=C(SCCO....
5 1ZOY - UQ1 C14 H18 O4 CC1=C(C(=O....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1YQ3 - TEO C4 H4 O5 C(=C(O)/[O....
2 2H89 - MLI C3 H2 O4 C(C(=O)[O-....
3 2H88 - TEO C4 H4 O5 C(=C(O)/[O....
4 2FBW - CBE C12 H13 N O2 S CC1=C(SCCO....
5 1ZOY - UQ1 C14 H18 O4 CC1=C(C(=O....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: TEO; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 TEO 1 1
2 TTN 0.409091 0.65
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2H88; Ligand: TEO; Similar sites found with APoc: 4
This union binding pocket(no: 1) in the query (biounit: 2h88.bio2) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 5ZYN SIN 32.3671
2 1Q9I FAD 32.3993
3 1Q9I TEO 32.3993
4 1D4D SIN 32.8671
Pocket No.: 2; Query (leader) PDB : 2H88; Ligand: TEO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2h88.bio3) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 2H88; Ligand: TEO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 2h88.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 2H88; Ligand: TEO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 2h88.bio4) has 18 residues
No: Leader PDB Ligand Sequence Similarity
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