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Receptor
PDB id Resolution Class Description Source Keywords
2GJ8 1.7 Å EC: 3.-.-.- STRUCTURE OF THE MNME G-DOMAIN IN COMPLEX WITH GDP*ALF4-, MG2+ AND K+ ESCHERICHIA COLI BL21(DE3) G-DOMAIN DIMER ALPHA-BETA-SANDWICH HYDROLASE
Ref.: DIMERISATION-DEPENDENT GTPASE REACTION OF MNME: HOW POTASSIUM ACTS AS GTPASE-ACTIVATING ELEMENT. EMBO J. V. 25 2940 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ALF GDP A:601;
B:611;
C:621;
D:631;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
Kd = 0.92 uM
543.152 n/a P(=O)...
K A:603;
B:613;
C:623;
D:633;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
39.098 K [K+]
MG A:602;
B:612;
C:622;
D:632;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
SE A:641;
C:643;
D:642;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
submit data
78.96 Se [SeH2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2GJ8 1.7 Å EC: 3.-.-.- STRUCTURE OF THE MNME G-DOMAIN IN COMPLEX WITH GDP*ALF4-, MG2+ AND K+ ESCHERICHIA COLI BL21(DE3) G-DOMAIN DIMER ALPHA-BETA-SANDWICH HYDROLASE
Ref.: DIMERISATION-DEPENDENT GTPASE REACTION OF MNME: HOW POTASSIUM ACTS AS GTPASE-ACTIVATING ELEMENT. EMBO J. V. 25 2940 2006
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 253 families.
1 2GJ8 Kd = 0.92 uM ALF GDP n/a n/a
2 2GJ9 - ALF GDP n/a n/a
3 2GJA - ALF GDP n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 2GJ8 Kd = 0.92 uM ALF GDP n/a n/a
2 2GJ9 - ALF GDP n/a n/a
3 2GJA - ALF GDP n/a n/a
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 173 families.
1 2GJ8 Kd = 0.92 uM ALF GDP n/a n/a
2 2GJ9 - ALF GDP n/a n/a
3 2GJA - ALF GDP n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ALF GDP; Similar ligands found: 105
No: Ligand ECFP6 Tc MDL keys Tc
1 ALF GDP 1 1
2 GDP ALF 1 1
3 ALF 5GP 0.857143 1
4 GDP AF3 0.8 1
5 GDP 7MG 0.71 0.879518
6 G 0.701149 0.9
7 5GP 0.701149 0.9
8 GDP 0.7 0.888889
9 GP3 0.688889 0.86747
10 GNH 0.673913 0.878049
11 GP2 0.663043 0.857143
12 GTP 0.659574 0.888889
13 G1R 0.652632 0.878049
14 GCP 0.652632 0.86747
15 9GM 0.645833 0.86747
16 GNP 0.645833 0.86747
17 G2P 0.645833 0.857143
18 GSP 0.645833 0.847059
19 GMV 0.642105 0.890244
20 G G 0.640777 0.890244
21 GAV 0.632653 0.857143
22 G2R 0.613861 0.857143
23 GMP 0.593023 0.802469
24 GPG 0.592233 0.857143
25 G1R G1R 0.591667 0.869048
26 6CK 0.588785 0.903614
27 PGD O 0.586777 0.784946
28 GCP G 0.586538 0.8875
29 Y9Z 0.584906 0.808989
30 GKE 0.584906 0.857143
31 GDD 0.584906 0.857143
32 GDC 0.584906 0.857143
33 GTG 0.579439 0.858824
34 GDR 0.579439 0.857143
35 GFB 0.579439 0.857143
36 YGP 0.575472 0.827586
37 G3A 0.574074 0.86747
38 G5P 0.568807 0.86747
39 ALF ADP 0.565657 0.9125
40 ADP ALF 0.565657 0.9125
41 A G 0.564103 0.901235
42 GKD 0.563636 0.857143
43 JB2 0.563636 0.857143
44 U A G G 0.559322 0.901235
45 GDX 0.558559 0.86747
46 GPD 0.558559 0.827586
47 G A A A 0.550847 0.890244
48 G3D 0.54902 0.876543
49 FEG 0.543103 0.808989
50 G4P 0.538462 0.876543
51 ZGP 0.538462 0.8
52 3GP 0.536842 0.864198
53 JB3 0.534483 0.847059
54 NGD 0.529915 0.879518
55 0O2 0.518519 0.876543
56 U2G 0.516949 0.837209
57 2MD 0.516667 0.8
58 CAG 0.516393 0.811111
59 G U 0.512605 0.869048
60 CG2 0.508333 0.837209
61 G C 0.504132 0.869048
62 MGD 0.504065 0.8
63 MD1 0.5 0.8
64 DBG 0.492188 0.847059
65 2GP 0.489796 0.853659
66 PGD 0.488189 0.827586
67 TPG 0.48062 0.757895
68 FE9 0.480315 0.755102
69 GPX 0.477064 0.841463
70 DGI 0.471154 0.823529
71 G G G C 0.46875 0.858824
72 G G G RPC 0.467742 0.845238
73 A G C C 0.465116 0.879518
74 GH3 0.458716 0.865854
75 G4M 0.456522 0.791209
76 DG 0.455446 0.833333
77 DGP 0.455446 0.833333
78 BGO 0.455285 0.825581
79 DGT 0.453704 0.823529
80 APC G U 0.453125 0.855422
81 DG DG 0.451327 0.837209
82 G C C C 0.451128 0.869048
83 P2G 0.45098 0.807229
84 AKW 0.443548 0.818182
85 P1G 0.442308 0.797619
86 IDP 0.438095 0.864198
87 ADP PO3 0.438095 0.8375
88 GGM 0.433071 0.806818
89 A G U 0.432624 0.858824
90 IMP 0.431373 0.875
91 AF3 ADP 3PG 0.430894 0.902439
92 G1G 0.427481 0.848837
93 VO4 ADP 0.418182 0.829268
94 ADP VO4 0.418182 0.829268
95 A G U U 0.417808 0.858824
96 G U34 0.417323 0.858824
97 5GP 5GP 0.416667 0.851852
98 G7M 0.413462 0.890244
99 GPC 0.412214 0.872093
100 SGP 0.409524 0.758621
101 R7I 0.409091 0.841463
102 R5I 0.409091 0.841463
103 PCG 0.407407 0.851852
104 C2E 0.407407 0.841463
105 35G 0.407407 0.851852
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2GJ8; Ligand: ALF GDP; Similar sites found with APoc: 660
This union binding pocket(no: 1) in the query (biounit: 2gj8.bio2) has 27 residues
No: Leader PDB Ligand Sequence Similarity
1 3N5C GDP None
2 1Z0A GDP None
3 2J0V GDP None
4 1YZN GNP None
5 2W83 GTP None
6 4LHW GNP None
7 1O3Y GTP None
8 1J2J GTP None
9 1T5C ADP None
10 4YLG GDP None
11 4U5X GNP None
12 1D5C GDP None
13 1JJV ATP None
14 1H65 GDP None
15 1ZD9 GDP None
16 5F1V 3VN None
17 4Q1A UDP None
18 4Q1A 2XZ None
19 3ZZQ TRP None
20 3ZZL TRP None
21 2FNA ADP None
22 3KIF GDL None
23 5C2N NAG None
24 6BYF CIT None
25 2OZE AGS None
26 2JDU MFU None
27 4TTQ ATP None
28 1YRB GDP 1.74419
29 1BG2 ADP 1.74419
30 2W58 ADP 1.74419
31 3COB ADP 1.74419
32 1RE0 GDP 1.74419
33 5GVR LMR 1.74419
34 5LB3 ADP 1.74419
35 3UIE ANP 1.74419
36 1WUU GLA 1.74419
37 5E5U MLI 1.74419
38 1V8K ANP 1.95122
39 3KIH GDL 2.06186
40 1M7G AV2 2.32558
41 2FAH GDP 2.32558
42 1I0B PEL 2.32558
43 6B8B ADP 2.32558
44 4ARU TLA 2.32558
45 1M7G ADP 2.32558
46 5WRI A3P 2.32558
47 1M7G ADX 2.32558
48 2HK9 ATR 2.32558
49 5WRJ A3P 2.32558
50 2QX0 PH2 2.51572
51 2BOI MFU 2.65487
52 2BME GNP 2.90698
53 2A5F GTP 2.90698
54 4FRZ ADP 2.90698
55 1SVK ALF GDP 2.90698
56 2DPY ADP 2.90698
57 4ZG4 VO4 ADP 2.90698
58 3G5N PB2 2.90698
59 5H4S RAM 2.90698
60 1E2K TMC 2.90698
61 3ITJ CIT 2.90698
62 5F90 GLA GAL 3.20513
63 5F90 LMR 3.20513
64 3NBC LAT 3.37838
65 3BIB PSF 3.44828
66 1I4D GDP 3.48837
67 3SBD GNP 3.48837
68 4PPF FLC 3.48837
69 1MH1 GNP 3.48837
70 1E96 GTP 3.48837
71 2FJU GSP 3.48837
72 2WKQ GTP 3.48837
73 1HE1 GDP 3.48837
74 1BH2 GSP 3.48837
75 2XT3 ADP 3.48837
76 1RYH GNP 3.48837
77 1HE1 AF3 3.48837
78 2ZEJ GDP 3.48837
79 1Y3A GDP 3.48837
80 2OM2 GDP 3.48837
81 2ZR9 DTP 3.48837
82 5KDO GDP 3.48837
83 1XMV ADP 3.48837
84 3B7G ANP 3.48837
85 4QOS ADP 3.48837
86 2ZTS ADP 3.48837
87 5K5Z ANP 3.48837
88 5HJQ I3P 3.48837
89 2O0J ADP 3.48837
90 3RC3 ANP 3.48837
91 3AI8 HNQ 3.48837
92 2ZX2 RAM 3.48837
93 3IUY AMP 3.48837
94 2X7I CIT 3.48837
95 2Z5F A3P 3.48837
96 1G8S MET 3.48837
97 5TE1 7A2 3.48837
98 4NZ6 DGL 3.48837
99 3QBT GNP 3.57143
100 1BO4 COA 3.57143
101 2B99 RDL 3.84615
102 5W75 GDP 4.06977
103 1G4U AF3 4.06977
104 5UIV ADP 4.06977
105 1G4U GDP 4.06977
106 3ZS9 ADP ALF 4.06977
107 2WOJ ADP ALF 4.06977
108 3EZ2 ADP 4.06977
109 3ZFD ANP 4.06977
110 4FCW ADP 4.06977
111 5X40 ACP 4.06977
112 1CR1 TTP 4.06977
113 1W5T ANP 4.06977
114 1W5T ADP 4.06977
115 1P4V GLY 4.06977
116 4GOX A3P 4.06977
117 5EE7 5MV 4.06977
118 4LYA ATP 4.06977
119 5XG5 A2G 4.13793
120 4KAX GTP 4.34783
121 6HKE LMR 4.40252
122 6HKE MLT 4.40252
123 4JLS 3ZE 4.60526
124 4J0Q GDP 4.65116
125 3VMF GTP 4.65116
126 1JJ7 ADP 4.65116
127 3LRE ADP 4.65116
128 3AQ4 GDP 4.65116
129 5BN3 ADP 4.65116
130 2OBM ADP 4.65116
131 1QF5 GDP 4.65116
132 1QF5 RPL 4.65116
133 6C90 ADP 4.65116
134 3TBK ANP 4.65116
135 1XKV ATP 4.65116
136 5XDR ADP 4.65116
137 1NJF ADP 4.65116
138 2J5V PCA 4.65116
139 2GWH A3P 4.65116
140 2CST MAE 4.65116
141 3IO3 ADP 4.65116
142 1NJF AGS 4.65116
143 5AHO TLA 4.65116
144 2QQ0 THM 4.65116
145 5IRN ADP 4.65116
146 6CS8 F9Y 4.65116
147 4QRH 0O2 4.65116
148 2QQ0 ANP 4.65116
149 3QVV A3P 4.65116
150 4V03 ADP 4.65116
151 5ZB0 TYD 4.65116
152 5ZB0 ADP 4.65116
153 2QQ0 TMP 4.65116
154 2QQ0 ADP 4.65116
155 1Z83 AP5 4.65116
156 1QF9 C5P 4.65116
157 1QF9 ALF 4.65116
158 1QF9 ADP 4.65116
159 2BNE U5P 4.65116
160 5HR5 ADP 4.65116
161 4A34 FUL 4.7619
162 6AIC AMP 5.14019
163 3H4S ADP 5.18518
164 3TNF GNP 5.23256
165 2ODE ALF GDP 5.23256
166 6AU6 GDP 5.23256
167 2WHX ADP 5.23256
168 4DKX GDP 5.23256
169 6A20 ADP 5.23256
170 5I0H ADP BEF 5.23256
171 4WZA ADP 5.23256
172 4WZA ACP 5.23256
173 4R43 GDP 5.23256
174 5J1J ANP 5.23256
175 6B4K ANP 5.23256
176 4WOP CTP 5.23256
177 5M7P ADP 5.23256
178 1KO8 6PG 5.23256
179 6FAA ADP 5.23256
180 3BFX A3P 5.23256
181 1AQU A3P 5.23256
182 1ZIN AP5 5.23256
183 5G41 AP5 5.23256
184 4NU0 AP5 5.23256
185 4MKF AP5 5.23256
186 4MKG AP5 5.23256
187 1S3G AP5 5.23256
188 3FB4 AP5 5.23256
189 3DC4 ADP 5.23256
190 3BER AMP 5.23256
191 2HIM ASN 5.23256
192 1G3Q ADP 5.23256
193 5G3Y ADP 5.23256
194 3TMK T5A 5.23256
195 2JLR ANP 5.23256
196 4O48 ASP 5.23256
197 4YS0 ADP 5.23256
198 1ION ADP 5.23256
199 2FFQ GSP 5.26316
200 1YZQ GNP 5.29412
201 1Z0J GTP 5.29412
202 1YVD GNP 5.32544
203 3HP8 SUC 5.45455
204 3HY2 ATP 5.45455
205 2UZH IPE 5.45455
206 5W76 GDP 5.81395
207 1D2E GDP 5.81395
208 5HCN GCP 5.81395
209 6CRK GDP 5.81395
210 5ZBR ANP 5.81395
211 1FP6 ADP 5.81395
212 1XX6 ADP 5.81395
213 1IWE IMP 5.81395
214 4PX9 ADP 5.81395
215 1U0J ADP 5.81395
216 3GVL SLB SIA 5.81395
217 5MZN ADP 5.81395
218 4WEI GLC GAL 5.81395
219 2BIF ANP 5.81395
220 2BIF SIN 5.81395
221 4JBL MET 5.81395
222 4PFO ADP 5.81395
223 1K6M AGS 5.81395
224 1IXI 2HP 5.81395
225 1OGD RIP 6.10687
226 2AJH MET 6.12245
227 3AB4 LYS 6.17978
228 3AB4 THR 6.17978
229 2FH5 GTP 6.39535
230 4RD0 GDP 6.39535
231 5W7Q GDP 6.39535
232 2QN6 GDP 6.39535
233 1B0U ATP 6.39535
234 3TK1 GDP 6.39535
235 4IDN GNP 6.39535
236 3B5J 12D 6.39535
237 1DS6 GDP 6.39535
238 3KJI ADP 6.39535
239 5KUT GDP 6.39535
240 2HF9 GSP 6.39535
241 4OHY ANP 6.39535
242 4R2I ANP 6.39535
243 4XTR ATP 6.39535
244 3FWY ADP 6.39535
245 4XVU ATP 6.39535
246 5EXT ADP 6.39535
247 1LVK MNT BEF 6.39535
248 4XTR ADP 6.39535
249 2QG6 NMN 6.39535
250 2DVZ GLU 6.39535
251 5VGR GDP 6.39535
252 1SVM ATP 6.39535
253 1R2Q GNP 6.47059
254 2F5X ASP 6.73077
255 3U6B GDP 6.97674
256 2BVN GNP 6.97674
257 5CK5 GDP 6.97674
258 3WXM GTP 6.97674
259 2BCG GDP 6.97674
260 1GOJ ADP 6.97674
261 2KIN ADP 6.97674
262 5KSP GDP 6.97674
263 5JBQ GDP 6.97674
264 1D8T GDP 6.97674
265 4P3Y GDP 6.97674
266 4G5G GDP 6.97674
267 2HCJ GDP 6.97674
268 5FG3 GDP 6.97674
269 3U6K GDP 6.97674
270 1WDT GTP 6.97674
271 5IRR GSP 6.97674
272 2PL3 ADP 6.97674
273 4XGU ADP 6.97674
274 5Y6N ADP 6.97674
275 5KSZ GCP 6.97674
276 4D81 ADP 6.97674
277 2CHG ANP 6.97674
278 1FNN ADP 6.97674
279 5Z69 AGS 6.97674
280 5L3W GDP 6.97674
281 4KVA GTP 6.97674
282 4PJ3 ANP 6.97674
283 3QF7 ANP 6.97674
284 4ZDJ UTP 6.97674
285 3BFV ADP 6.97674
286 5AK0 8V1 6.97674
287 4M3P HCS 6.97674
288 5I34 GDP 6.97674
289 5N69 ADP 6.97674
290 1UJ2 ADP 6.97674
291 1UJ2 C5P 6.97674
292 1WY7 SAH 6.97674
293 1ZUI SKM 7.14286
294 2W2X GSP 7.25806
295 1W7J ADP BEF 7.28477
296 1NRJ GTP 7.33945
297 1SKQ GDP 7.55814
298 1G7C 5GP 7.55814
299 1M7B GTP 7.55814
300 5U32 GDP 7.55814
301 1GWN GTP 7.55814
302 4U00 ADP 7.55814
303 5YT0 GDP 7.55814
304 1TQ4 GDP 7.55814
305 2WIC GNP 7.55814
306 2CDN ADP 7.55814
307 1DAR GDP 7.55814
308 4YMU ATP 7.55814
309 3CPJ GDP 7.55814
310 4YDS ATP 7.55814
311 1SQ5 ADP 7.55814
312 1R0X ATP 7.55814
313 4IHQ ADP 7.55814
314 2IS6 ADP 7.55814
315 4HSE ADP 7.55814
316 3KTA AP5 7.55814
317 1L2T ATP 7.55814
318 1Y63 ADP 7.55814
319 4BQS K2Q 7.55814
320 4BQS ADP 7.55814
321 4NE2 SH2 7.55814
322 4NE2 ADP 7.55814
323 2JK0 ASP 7.55814
324 4NCN GTP 8.13953
325 4TMZ GSP 8.13953
326 1FQJ ALF 8.13953
327 2XTZ GSP 8.13953
328 2VVG ADP 8.13953
329 2PZE ATP 8.13953
330 1FQJ GDP 8.13953
331 4WZ6 ATP 8.13953
332 2Y65 ADP 8.13953
333 1YZG GDP 8.13953
334 2EFE GNH 8.13953
335 1OXV ANP 8.13953
336 4E03 ADP 8.13953
337 1Z6T ADP 8.13953
338 1IN4 ADP 8.13953
339 4LJ9 ACP 8.13953
340 1IHU ADP 8.13953
341 1Z82 G3H 8.13953
342 1Z82 G3P 8.13953
343 3Q9L ATP 8.13953
344 1IHU AF3 8.13953
345 1NY5 ADP 8.13953
346 5WC2 ADP 8.13953
347 3QXC ATP 8.13953
348 1D2N ANP 8.13953
349 2Q2Y ADP 8.13953
350 3QKT ANP 8.13953
351 2Q2Y MKR 8.13953
352 1KK8 BEF ADP 8.13953
353 1HFE CYS 8.13953
354 1NST A3P 8.13953
355 4ZNL BEF ADP 8.13953
356 1LDN FBP 8.13953
357 1B7T ADP 8.13953
358 4GN8 ASO 8.13953
359 2QZ4 ADP 8.13953
360 1G16 GDP 8.23529
361 3WY9 GDP 8.52535
362 3WYA GDP 8.52535
363 4PYA 2X3 8.69565
364 5H7J GCP 8.72093
365 5H7K GDP 8.72093
366 1G6H ADP 8.72093
367 1ZJ6 G3D 8.72093
368 4B47 GDP 8.72093
369 5GOE GDP 8.72093
370 5OEC GDP 8.72093
371 5TSH ANP 8.72093
372 5TSH ADP 8.72093
373 3BOS CDP 8.72093
374 3ZQ6 ADP ALF 8.72093
375 5LTJ ADP 8.72093
376 1VHT BA3 8.72093
377 5LTJ BEF 8.72093
378 1P9B GDP 8.72093
379 1CT9 GLN 8.72093
380 4IOK XPO 8.72093
381 4IOK ADP 8.72093
382 2ZFI ADP 8.72093
383 2C9O ADP 8.72093
384 1P9B HDA 8.72093
385 2D3N GLC GLC GLC 8.72093
386 2VB6 ADP BEF 8.72483
387 2J59 GTP 8.92857
388 5J1S ATP 8.94309
389 5LEF GTP 9.09091
390 1LOJ URI 9.1954
391 2AWN ADP 9.30233
392 1F9V ADP 9.30233
393 1XP8 AGS 9.30233
394 1DAK DPU 9.30233
395 1DAK ADP 9.30233
396 3RLF ANP 9.30233
397 4GBM A3P 9.30233
398 1Z0N BCD 9.375
399 1F2U ATP 9.39597
400 3DOE GTP 9.88372
401 1KSH GDP 9.88372
402 1LVG ADP 9.88372
403 1RRC ADP 9.88372
404 2CE7 ADP 9.88372
405 4IEE AGS 9.88372
406 5FHD ADP ALF 9.88372
407 5FTB ANP 9.88372
408 1WRA PC 9.88372
409 5H67 ATP 9.88372
410 1GXU 2HP 9.89011
411 4QM7 GTP 9.94152
412 3FKQ ATP 10.1877
413 2O66 FLC 10.3704
414 4OI4 ATP 10.4348
415 2C78 GNP 10.4651
416 2C77 GNP 10.4651
417 1CS4 GSP 10.4651
418 5ZXD ATP 10.4651
419 4H1V GNP 10.4651
420 4WXJ GLU 10.4651
421 5NM7 GLY 10.4651
422 3FXU TSU 10.4651
423 5XKT GNP 10.5
424 1HTW ADP 10.7595
425 3Q72 GNP 10.8434
426 2Z49 AMG 11.0465
427 4A4Z ANP 11.0465
428 4TL6 ANP 11.0465
429 1M0S CIT 11.0465
430 1UKZ ADP 11.0465
431 3LN9 FLC 11.5108
432 4ZKD GDP 11.6279
433 5L3S GNP 11.6279
434 4P4T GDP 11.6279
435 5L3V GDP 11.6279
436 5L3S G 11.6279
437 1X6V ADP 11.6279
438 3AIA SAM 11.6279
439 1AKY AP5 11.6279
440 2GJP MAL 11.6279
441 3A4M ADP 11.6279
442 4G9N NGA 11.8881
443 2NCD ADP 12.2093
444 4HI0 GDP 12.2093
445 1G41 ADP 12.2093
446 1OFH ADP 12.2093
447 2GKS ADP 12.2093
448 4X8O AP5 12.2093
449 3IIJ ADP 12.2093
450 2R4V GSH 12.2093
451 2CJU PHX 12.3894
452 1APZ ASP 12.766
453 4CVN ADP 12.7907
454 1S9D GDP 12.7907
455 1Z0F GDP 12.7907
456 1W0J ADP 12.7907
457 1W0J ADP BEF 12.7907
458 5CIC 51R 12.963
459 1Z0K GTP 13.0435
460 2CBZ ATP 13.3721
461 5IFS ADP 13.3721
462 4RZ3 ADP 13.3721
463 2RGX AP5 13.3721
464 1RJW ETF 13.3721
465 1HXD BTN 13.3721
466 1YTM ATP 13.3721
467 6H5E ANP 13.3721
468 4YJ1 ADP 13.9535
469 4R98 GNH 13.9535
470 2FSH ANP 13.9535
471 2PEZ DAT 13.9535
472 2PEZ GGZ 13.9535
473 3FVQ ATP 13.9535
474 2OFW ADX 13.9535
475 3NHB ADP 14.5349
476 2CJW GDP 14.5349
477 1VBO MAN MAN MAN 14.7651
478 5F7Y GLC GAL NAG GAL FUC A2G 15
479 3T12 GDP ALF 15.1163
480 2HT6 GDP 15.1163
481 3T1O GDP 15.1163
482 4LPS GDP 15.1163
483 3DZD ADP 15.1163
484 1OYY AGS 15.1163
485 2BEK ATP 15.1163
486 2ZJ5 ADP 15.1163
487 2DX7 CIT 15.1163
488 4HDO GNP 15.5689
489 4HDQ GNP 15.5689
490 3X1Z GNP 15.5689
491 5UPK GNP 15.6977
492 1JI0 ATP 15.6977
493 3EWA ANP 15.6977
494 3R7F CP 15.6977
495 4Y4V DAL 15.6977
496 1GUA GNP 16.1677
497 1UAD GNP 16.2791
498 3PCR GTP 16.2791
499 3RWO GDP 16.2791
500 3B9Q MLI 16.2791
501 2A9K GDP 16.2791
502 1RJ9 GCP 16.2791
503 2A5J GDP 16.2791
504 2F9L GDP 16.2791
505 5L3R GCP 16.2791
506 2IYL GDP 16.2791
507 4KVG GTP 16.6667
508 1U8Z GDP 16.6667
509 3H86 AP5 16.6667
510 4PC3 GDP 16.8605
511 4LX0 BEF GDP 16.8605
512 2OG2 MLI 16.8605
513 3DKP ADP 16.8605
514 1VKJ A3P 16.8605
515 3BC1 GNP 16.9492
516 6BSX GDP 17.4419
517 1F5N GNP 17.4419
518 3T5G GDP 17.4419
519 6BSX E7S 17.4419
520 3P4X ADP 17.4419
521 2XAU ADP 17.4419
522 2GK6 ADP 17.4419
523 2D7D ADP 17.4419
524 1TU3 GNP 17.7215
525 1ZC3 GNP 18.0233
526 1G7S GDP 18.6047
527 3W5J GDP 18.6047
528 5TQZ GLC 18.6667
529 2X77 GDP 19.0476
530 3DEF GDP 19.186
531 5VHC BEF ADP 19.186
532 1KK1 GNP 19.7674
533 2RCN GDP 19.7674
534 3CNL GNP 19.7674
535 3FYH ADP 19.7674
536 2V7Q ADP 20
537 2V7Q ATP 20
538 2CK3 ANP 20
539 2CK3 ADP 20
540 3T34 GDP 20.3488
541 5BQ5 ADP BEF 20.3488
542 5H68 AGS 20.9302
543 1NN5 2DT 20.9302
544 1NN5 ANP 20.9302
545 3CX8 GSP 21.5116
546 1ZCB GDP 21.5116
547 3AB3 GDP 21.5116
548 1PUJ GNP 22.093
549 4JLV ADP 22.6744
550 1KAO GDP 23.2558
551 4NON GDP 23.2558
552 5MVR ADP 24.6914
553 2YOH WMJ 25
554 3E70 GDP 26.1628
555 2WJH GDP 27.1084
556 2WJH FLC 27.1084
557 1UPT GTP 27.4854
558 4HAT GNP 27.907
559 6CIT GNP 27.907
560 5DHF GNP 27.907
561 5UWP GNP 27.907
562 5DIF GNP 27.907
563 5UWR GNP 27.907
564 5UWQ GNP 27.907
565 5UWO GNP 27.907
566 1WA5 GTP 27.907
567 5UWT GNP 27.907
568 5UWW GNP 27.907
569 5UWI GNP 27.907
570 5UWH GNP 27.907
571 5UWU GNP 27.907
572 5UWS GNP 27.907
573 3M1I GTP 27.907
574 3WYF GTP 27.907
575 5DI9 GNP 27.907
576 3WYG GTP 27.907
577 4YC7 GNP 27.907
578 4ITR GDP 27.907
579 3GJ3 GDP 27.907
580 3CH5 GDP 27.907
581 2WMO GTP 27.907
582 2WJG GDP 27.907
583 4DID GDP 27.907
584 2EW1 GNP 28.4884
585 5JCP GDP ALF 28.4884
586 3GJX GTP 28.4884
587 1M2O GNP 28.4884
588 4XOI GTP 28.4884
589 4XSH GSP 28.4884
590 5HPY GDP 28.4884
591 2ZPA ADP 28.4884
592 3GJ7 GDP 29.0698
593 3GJ4 GDP 29.0698
594 3GJ5 GDP 29.0698
595 4D0N GDP 29.0698
596 4BAS GNP 29.0698
597 6BCA GSP 29.0698
598 6BCB GSP 29.0698
599 6BC0 GSP 29.0698
600 3GJ8 GDP 29.0698
601 1F6B GDP 29.0698
602 3LXR GDP 29.0698
603 1X1R GDP 29.2135
604 2QTV GNP 29.3413
605 5EE5 GTP 29.8246
606 1Z06 GNP 30.2326
607 5SZH GNP 30.2326
608 3TKL GTP 30.2326
609 3NKV GNP 30.2326
610 3SFV GDP 30.2326
611 1KY3 GDP 30.2326
612 1R4A GNP 30.303
613 1S8F GDP 30.814
614 2GCO GNP 30.814
615 2GCN GDP 30.814
616 1Z08 GNP 31.1765
617 5O74 GDP 31.3953
618 3Q85 GNP 31.9527
619 4DCT GDP 31.9767
620 1MKY GDP 32.5581
621 5M04 GDP 33.1395
622 1OIV GDP 33.7209
623 1FZQ GDP 34.3023
624 4GOJ GNP 34.3023
625 4ZI2 GNP 34.3023
626 1OIX GDP 34.3023
627 1Z2A GDP 34.5238
628 4C4P GNP 34.8837
629 5JCZ GDP 34.8837
630 3ZIA ATP 34.8837
631 3ZIA ADP 34.8837
632 5WDR GNP 35.0877
633 1EK0 GNP 35.2941
634 4D0G GTP 36.0465
635 2Y8E GNP 37.2093
636 5TB5 GDP 37.8378
637 5TAR GDP 37.8378
638 1VG1 GDP 38.3721
639 1VG8 GNP 38.3721
640 1VG0 GDP 38.3721
641 1VG9 GDP 38.3721
642 5UQW GDP 38.6243
643 3MJH GTP 38.6905
644 3E5H GNP 38.9535
645 5Z2M GTP 38.9535
646 4V0K GDP 39.645
647 5DI3 GNP 40.1163
648 4M9Q GNP 40.1163
649 2C5L GTP 40.4624
650 3A1S GDP 40.6977
651 4K81 GTP 40.9357
652 3DDC GNP 41.5663
653 5E95 GDP 41.6667
654 5OCG GNP 41.8605
655 1MR3 G3D 41.8605
656 2UZI GTP 42.1687
657 3KUD GDP 42.1687
658 1CLU DBG 42.7711
659 5O2T GSP 43.1953
660 3PQC GDP 44.186
Pocket No.: 2; Query (leader) PDB : 2GJ8; Ligand: ALF GDP; Similar sites found with APoc: 18
This union binding pocket(no: 2) in the query (biounit: 2gj8.bio2) has 27 residues
No: Leader PDB Ligand Sequence Similarity
1 1J1R ADE None
2 2WPB ZZI None
3 2JFN GLU 2.32558
4 2BO4 FLC 2.90698
5 5F90 GLA GAL BGC 5VQ 3.20513
6 1GPE FAD 3.48837
7 4YSX MLI 4.65116
8 5BSH PRO 5.23256
9 2J0W ASP 5.23256
10 1YZX GSF 5.23256
11 4CP8 MLI 5.81395
12 5L2R MLA 6.39535
13 3GDN MXN 6.39535
14 2ZUX RAM 7.55814
15 4GNC ASO 8.13953
16 4GYS MLI 11.0465
17 3WMX THR 19.7674
18 1XXA ARG 24.359
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