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Receptor
PDB id Resolution Class Description Source Keywords
2FSH 2 Å EC: 7.-.-.- COMPLEX SECA:AMP-PNP FROM ESCHERICHIA COLI ESCHERICHIA COLI ATPASE DNA-RNA HELICASE PROTEIN TRANSLOCATION SECA PROTEIN TRANSPORT
Ref.: STRUCTURE OF DIMERIC SECA, THE ESCHERICHIA COLI PREPROTEIN TRANSLOCASE MOTOR. J.MOL.BIOL. V. 366 1545 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP A:900;
B:901;
Valid;
Valid;
none;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2FSH 2 Å EC: 7.-.-.- COMPLEX SECA:AMP-PNP FROM ESCHERICHIA COLI ESCHERICHIA COLI ATPASE DNA-RNA HELICASE PROTEIN TRANSLOCATION SECA PROTEIN TRANSPORT
Ref.: STRUCTURE OF DIMERIC SECA, THE ESCHERICHIA COLI PREPROTEIN TRANSLOCASE MOTOR. J.MOL.BIOL. V. 366 1545 2007
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 293 families.
1 2FSG - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 2FSH - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
3 2FSI - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 250 families.
1 2FSG - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 2FSH - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
3 2FSI - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 204 families.
1 4YS0 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 2FSG - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
3 2FSH - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
4 2FSI - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 373
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 AP5 0.802632 0.945205
5 ADP 0.802632 0.972222
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 HEJ 0.772152 0.972222
9 ATP 0.772152 0.972222
10 AT4 0.769231 0.933333
11 AN2 0.769231 0.986111
12 5FA 0.7625 0.972222
13 AQP 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 AR6 0.740741 0.945205
18 APR 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 SAP 0.731707 0.921053
22 AGS 0.731707 0.921053
23 A 0.723684 0.944444
24 AMP 0.723684 0.944444
25 ATF 0.717647 0.933333
26 ADX 0.716049 0.851852
27 CA0 0.716049 0.92
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 AP2 0.679012 0.933333
33 A12 0.679012 0.933333
34 APC 0.678571 0.933333
35 T99 0.674419 0.933333
36 TAT 0.674419 0.933333
37 A22 0.674157 0.958904
38 SRA 0.670886 0.894737
39 SRP 0.670455 0.883117
40 5AL 0.666667 0.906667
41 A1R 0.659341 0.884615
42 ADQ 0.659341 0.92
43 A3R 0.659341 0.884615
44 3OD 0.648936 0.92
45 BIS 0.648936 0.909091
46 5SV 0.648352 0.82716
47 9X8 0.645161 0.896104
48 OAD 0.645161 0.92
49 25L 0.642105 0.958904
50 AMO 0.641304 0.907895
51 G5P 0.636364 0.897436
52 DLL 0.634409 0.906667
53 AHX 0.634409 0.897436
54 00A 0.634409 0.860759
55 ADV 0.632184 0.907895
56 RBY 0.632184 0.907895
57 ADP PO3 0.632184 0.917808
58 NB8 0.631579 0.897436
59 25A 0.630435 0.945205
60 OOB 0.630435 0.906667
61 8QN 0.630435 0.906667
62 G3A 0.626263 0.897436
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 TXA 0.614583 0.907895
67 1ZZ 0.614583 0.819277
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 9ZD 0.612903 0.909091
71 9ZA 0.612903 0.909091
72 3UK 0.610526 0.894737
73 SON 0.604651 0.907895
74 ADP ALF 0.604396 0.848101
75 ALF ADP 0.604396 0.848101
76 PR8 0.604167 0.829268
77 B5V 0.604167 0.883117
78 WAQ 0.604167 0.860759
79 4UV 0.6 0.871795
80 GAP 0.6 0.87013
81 PTJ 0.597938 0.873418
82 FYA 0.597938 0.881579
83 VO4 ADP 0.597826 0.906667
84 ADP VO4 0.597826 0.906667
85 LMS 0.597561 0.829268
86 UP5 0.596154 0.896104
87 FA5 0.59596 0.883117
88 YAP 0.59596 0.871795
89 PAP 0.595506 0.958333
90 A4P 0.59434 0.823529
91 XAH 0.59 0.841463
92 4UU 0.588235 0.871795
93 AFH 0.588235 0.8625
94 9SN 0.585859 0.85
95 2A5 0.58427 0.894737
96 T5A 0.583333 0.821429
97 DQV 0.582524 0.932432
98 NAI 0.580952 0.884615
99 B5M 0.58 0.871795
100 B5Y 0.58 0.871795
101 ITT 0.579545 0.917808
102 ATR 0.577778 0.944444
103 OMR 0.575472 0.831325
104 5AS 0.574713 0.781609
105 YLP 0.571429 0.8
106 48N 0.571429 0.873418
107 AP0 0.570093 0.873418
108 4TC 0.570093 0.873418
109 7D3 0.569767 0.881579
110 ADJ 0.568807 0.831325
111 GNP 0.568421 0.922078
112 9GM 0.568421 0.922078
113 DAL AMP 0.568421 0.881579
114 6V0 0.566038 0.873418
115 TXD 0.566038 0.884615
116 DND 0.566038 0.907895
117 NAX 0.566038 0.851852
118 4UW 0.566038 0.839506
119 NXX 0.566038 0.907895
120 XYA 0.565789 0.821918
121 RAB 0.565789 0.821918
122 ADN 0.565789 0.821918
123 AOC 0.564706 0.8
124 7D4 0.561798 0.881579
125 ADP BMA 0.561224 0.894737
126 TXE 0.560748 0.884615
127 TYM 0.560748 0.883117
128 GA7 0.557692 0.883117
129 YLC 0.555556 0.819277
130 YLB 0.555556 0.8
131 139 0.554545 0.851852
132 5N5 0.551282 0.797297
133 JB6 0.55 0.860759
134 LAQ 0.54717 0.819277
135 F2R 0.544643 0.843373
136 MYR AMP 0.544554 0.797619
137 5CD 0.544304 0.783784
138 A4D 0.544304 0.797297
139 80F 0.54386 0.821429
140 7MD 0.542857 0.864198
141 6AD 0.542553 0.886076
142 A2R 0.541667 0.958904
143 UPA 0.541284 0.884615
144 YLA 0.540541 0.8
145 A A 0.54 0.918919
146 BTX 0.539823 0.821429
147 COD 0.539823 0.793103
148 HFD 0.537634 0.921053
149 G5A 0.537634 0.781609
150 3DH 0.535714 0.753247
151 AYB 0.535714 0.790698
152 CNA 0.535714 0.907895
153 BT5 0.535088 0.811765
154 ATP A A A 0.533981 0.905405
155 IOT 0.531532 0.811765
156 MTA 0.53012 0.753247
157 3AM 0.529412 0.90411
158 A3P 0.52809 0.944444
159 PPS 0.526316 0.851852
160 NAD 0.526316 0.906667
161 EP4 0.52439 0.734177
162 7D5 0.52381 0.855263
163 AMP DBH 0.52381 0.87013
164 J7C 0.522727 0.75
165 A5A 0.520833 0.809524
166 EAD 0.520661 0.851852
167 TSB 0.520408 0.821429
168 AHZ 0.518519 0.797619
169 DTA 0.518072 0.766234
170 M2T 0.518072 0.716049
171 A3D 0.517241 0.894737
172 6RE 0.517241 0.740741
173 YLY 0.516949 0.790698
174 SSA 0.515464 0.802326
175 NA7 0.514852 0.933333
176 ARG AMP 0.514019 0.809524
177 AR6 AR6 0.514019 0.893333
178 7MC 0.513514 0.843373
179 A2P 0.511111 0.930556
180 52H 0.510204 0.781609
181 VMS 0.510204 0.790698
182 54H 0.510204 0.790698
183 TYR AMP 0.509434 0.848101
184 TAD 0.509259 0.8625
185 NAQ 0.508333 0.85
186 A3N 0.505618 0.766234
187 AV2 0.505155 0.893333
188 53H 0.50505 0.781609
189 5CA 0.50505 0.802326
190 8X1 0.50505 0.755556
191 ARU 0.504951 0.839506
192 ZID 0.504132 0.894737
193 P1H 0.504 0.831325
194 NAE 0.5 0.871795
195 3AT 0.5 0.945205
196 AVV 0.5 0.873418
197 P5A 0.495146 0.747253
198 NSS 0.49505 0.802326
199 LSS 0.49505 0.764045
200 DSZ 0.49505 0.802326
201 N0B 0.491803 0.8
202 AF3 ADP 3PG 0.491071 0.817073
203 NVA LMS 0.490196 0.755556
204 DAT 0.489362 0.881579
205 IMO 0.488889 0.90411
206 ZAS 0.488636 0.792208
207 FDA 0.488372 0.813953
208 NAJ PZO 0.487395 0.85
209 4TA 0.487179 0.788235
210 LPA AMP 0.486486 0.797619
211 LEU LMS 0.485437 0.755556
212 DTP 0.484536 0.881579
213 V3L 0.484536 0.945205
214 S4M 0.483516 0.651685
215 GJV 0.483516 0.731707
216 DZD 0.483051 0.8625
217 2AM 0.482759 0.917808
218 5AD 0.481013 0.726027
219 GSU 0.480769 0.781609
220 KAA 0.480769 0.755556
221 NDE 0.480315 0.907895
222 M24 0.479339 0.851852
223 MAO 0.478261 0.761905
224 NEC 0.477778 0.727273
225 DSH 0.477778 0.707317
226 FAS 0.477273 0.831325
227 FAD 0.477273 0.831325
228 RGT 0.476636 0.933333
229 9K8 0.47619 0.698925
230 G A A A 0.474576 0.85
231 0WD 0.474576 0.897436
232 FNK 0.474074 0.786517
233 5X8 0.473684 0.74359
234 6FA 0.473282 0.821429
235 NDC 0.472868 0.85
236 FB0 0.472868 0.786517
237 YSA 0.472222 0.781609
238 7DD 0.468085 0.958333
239 OVE 0.466667 0.881579
240 MHZ 0.463158 0.701149
241 8PZ 0.462963 0.802326
242 A G 0.462185 0.860759
243 AMP NAD 0.462185 0.881579
244 A3G 0.461538 0.779221
245 NAJ PYZ 0.459677 0.809524
246 6C6 0.459184 0.858974
247 SFG 0.458333 0.730769
248 U A G G 0.458333 0.860759
249 7D7 0.45679 0.723684
250 128 0.45614 0.8
251 SFD 0.455224 0.736842
252 6IA 0.454545 0.817073
253 DDS 0.454545 0.855263
254 GDP 0.454545 0.896104
255 ODP 0.453782 0.886076
256 NJP 0.453782 0.921053
257 7DT 0.453608 0.958333
258 A7D 0.452632 0.75641
259 Z5A 0.452381 0.802326
260 WSA 0.452174 0.790698
261 U A 0.45082 0.884615
262 7C5 0.45045 0.797468
263 FAY 0.449275 0.841463
264 NDP 0.449153 0.897436
265 SA8 0.44898 0.690476
266 A5D 0.44898 0.766234
267 71V 0.446809 0.884615
268 GGZ 0.446602 0.804878
269 RFL 0.446043 0.802326
270 2SA 0.445545 0.907895
271 SAI 0.444444 0.716049
272 GP3 0.444444 0.897436
273 SAH 0.444444 0.725
274 PO4 PO4 A A A A PO4 0.443396 0.878378
275 A A A 0.443396 0.881579
276 4YB 0.442478 0.764045
277 SMM 0.441176 0.670455
278 S7M 0.441176 0.674419
279 GTP 0.441176 0.896104
280 Y3J 0.440476 0.706667
281 SAM 0.44 0.674419
282 649 0.439655 0.747253
283 12D 0.438596 0.809524
284 A3S 0.4375 0.789474
285 NPW 0.436975 0.864198
286 GCP 0.436893 0.873418
287 AAT 0.435644 0.690476
288 GNH 0.435644 0.909091
289 EEM 0.435644 0.674419
290 ETB 0.435484 0.813953
291 DCA 0.435484 0.804598
292 N6P 0.433962 0.890411
293 NZQ 0.433333 0.886076
294 TXP 0.433333 0.897436
295 PGS 0.43299 0.860759
296 APU 0.432203 0.871795
297 PUA 0.432 0.8625
298 62F 0.431655 0.841463
299 F2N 0.431507 0.795455
300 DA 0.430108 0.855263
301 D5M 0.430108 0.855263
302 J7V 0.429688 0.813953
303 NIA 0.428571 0.848101
304 COA 0.428571 0.804598
305 6K6 0.428571 0.905405
306 A3T 0.428571 0.8
307 0T1 0.428571 0.804598
308 P5F 0.427586 0.804598
309 AAM 0.425532 0.944444
310 0UM 0.424528 0.682353
311 8Q2 0.423729 0.775281
312 G1R 0.423077 0.884615
313 AMZ 0.422222 0.891892
314 C2R 0.422222 0.88
315 A U 0.420168 0.848101
316 IDP 0.42 0.894737
317 GSP 0.419048 0.851852
318 30N 0.418605 0.736842
319 CAO 0.418605 0.777778
320 DG1 0.418605 0.897436
321 1DG 0.418605 0.897436
322 COS 0.418605 0.786517
323 AMX 0.418605 0.813953
324 TM1 0.418182 0.797619
325 A6D 0.416667 0.746988
326 K15 0.416667 0.666667
327 V1N 0.415929 0.893333
328 CMX 0.415385 0.804598
329 SCO 0.415385 0.804598
330 GEK 0.415094 0.719512
331 XNP 0.414634 0.851852
332 NHD 0.414634 0.881579
333 9JJ 0.413793 0.841463
334 AIR 0.413793 0.876712
335 COK 0.413534 0.786517
336 G2R 0.412844 0.8625
337 ACO 0.412214 0.777778
338 FAM 0.412214 0.786517
339 FCX 0.412214 0.777778
340 NAP 0.410853 0.92
341 FA9 0.409396 0.843373
342 SXZ 0.409091 0.694118
343 HAX 0.409091 0.806818
344 TAP 0.407692 0.884615
345 2MC 0.407407 0.752688
346 62X 0.407407 0.651685
347 GKE 0.40708 0.8625
348 GDC 0.40708 0.8625
349 GDD 0.40708 0.8625
350 3KK 0.406015 0.786517
351 FYN 0.406015 0.804598
352 NVA 2AD 0.405941 0.740741
353 NA0 0.40458 0.907895
354 101 0.404255 0.855263
355 G 0.40404 0.883117
356 5GP 0.40404 0.883117
357 HDV 0.403846 0.87013
358 MGP 0.403846 0.8625
359 OXK 0.402985 0.786517
360 MCD 0.402985 0.786517
361 CA6 0.402985 0.714286
362 SOP 0.402985 0.786517
363 3AD 0.402299 0.783784
364 S8M 0.401869 0.78481
365 YE1 0.40146 0.795455
366 NMX 0.4 0.782609
367 7RP 0.4 0.902778
368 2VA 0.4 0.779221
369 1VU 0.4 0.777778
370 CO6 0.4 0.786517
371 CMC 0.4 0.786517
372 6G0 0.4 0.8625
373 GMV 0.4 0.873418
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2FSH; Ligand: ANP; Similar sites found with APoc: 708
This union binding pocket(no: 1) in the query (biounit: 2fsh.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 2ZJ5 ADP 1.11111
2 2Z49 AMG 1.15741
3 3ITJ CIT 1.18343
4 2CE7 ADP 1.2605
5 1X6V ADP 1.42857
6 1P72 ADP 1.49701
7 4M52 FAD 1.50215
8 1XKV ATP 1.51229
9 1F5N GNP 1.52027
10 4NCN GTP 1.53173
11 5I34 GDP 1.5873
12 1QHG ATP 1.65746
13 3OI7 OI7 1.71233
14 2C77 GNP 1.7284
15 2C78 GNP 1.7284
16 2OBM ADP 1.72911
17 3GBR PRP 1.73913
18 1R0X ATP 1.74825
19 4IHQ ADP 1.75439
20 1NHX FTB 1.76
21 1NHX PEP 1.76
22 2GMV UN8 1.76
23 2GMV PEP 1.76
24 1D2E GDP 1.76322
25 4LYA ATP 1.78891
26 3TBK ANP 1.8018
27 1P9B GDP 1.80995
28 5MZN ADP 1.86916
29 5CK5 GDP 1.89873
30 2BIF ANP 1.91898
31 2BIF SIN 1.91898
32 1WDT GTP 1.95489
33 6CS8 F9Y 1.9802
34 1G7S GDP 2.0202
35 2VTD LKM 2.02247
36 1YQT ADP 2.04461
37 3B8I OXL 2.09059
38 6B4K ANP 2.09302
39 1LVK MNT BEF 2.09974
40 2WKQ GTP 2.10843
41 4H1V GNP 2.16802
42 2GKS ADP 2.1978
43 1IHU AF3 2.20713
44 1IHU ADP 2.20713
45 1ZUA TOL 2.2082
46 1ZUA NAP 2.2082
47 5M04 GDP 2.22222
48 5VHC BEF ADP 2.22743
49 5YV5 ADP 2.23881
50 5L3W GDP 2.28758
51 1SKQ GDP 2.29885
52 6DEF GCP 2.30179
53 3WYA GDP 2.30415
54 1K6M AGS 2.31481
55 4TMZ GSP 2.31884
56 1QF5 RPL 2.32019
57 1QF5 GDP 2.32019
58 1CR1 TTP 2.36486
59 3BFX A3P 2.36486
60 2NCD ADP 2.38095
61 6G14 G4P 2.38095
62 4NE2 ADP 2.39521
63 4NE2 SH2 2.39521
64 2GK6 ADP 2.40385
65 3TK1 GDP 2.42424
66 5FAL SKT 2.45536
67 5FAL COA 2.45536
68 1VKJ A3P 2.45614
69 1PUJ GNP 2.48227
70 4P4T GDP 2.5
71 2VVG ADP 2.57143
72 4GID 0GH 2.57732
73 1SQ5 ADP 2.5974
74 2X7I CIT 2.5974
75 4ZKD GDP 2.60521
76 5GOE GDP 2.60664
77 2XT3 ADP 2.61628
78 4W93 3L9 2.62097
79 2I4I AMP 2.63789
80 5M7P ADP 2.64317
81 1Z06 GNP 2.6455
82 5BQ5 ADP BEF 2.6455
83 1IZC PYR 2.65487
84 5ZBR ANP 2.66667
85 4LC1 GDP 2.67062
86 3COB ADP 2.71003
87 4UXH T5A 2.71739
88 4YMU ATP 2.72727
89 2B8W ALF 5GP 2.7439
90 5H7K GDP 2.77078
91 1T26 NAI 2.79503
92 1T26 GBD 2.79503
93 4AG5 ADP 2.80612
94 5ERR ADP 2.86396
95 3FWY ADP 2.86624
96 3IO3 ADP 2.87356
97 2VOS ADP 2.87474
98 4RD0 GDP 2.89157
99 2F3R G5P 2.89855
100 2WHX ADP 2.91262
101 5IRR GSP 2.92208
102 1XP8 AGS 2.93083
103 2IS6 ADP 2.94118
104 4LJ9 ACP 2.94985
105 1YVD GNP 2.95858
106 1IN4 ADP 2.99401
107 4KBF AMP 3.0137
108 2F9L GDP 3.01508
109 2QG6 NMN 3.01508
110 1ZCB GDP 3.03867
111 3QVV A3P 3.05085
112 3QVV 3QV 3.05085
113 4WZA ACP 3.06513
114 4WZA ADP 3.06513
115 4XGU ADP 3.06604
116 5EXT ADP 3.07692
117 1GOJ ADP 3.09859
118 3MD0 GDP 3.09859
119 5I0H ADP BEF 3.10391
120 3H86 AP5 3.125
121 5IRN ADP 3.13253
122 1F9V ADP 3.17003
123 5UQW GDP 3.1746
124 5OCG GNP 3.1746
125 5GLN XYP XYP XYP 3.19767
126 5FJJ MAN 3.20665
127 4ZG4 VO4 ADP 3.27225
128 4B47 GDP 3.30579
129 3BOS CDP 3.30579
130 2ZW5 COA 3.32226
131 3T34 GDP 3.33333
132 1FNN ADP 3.3419
133 1X1R GDP 3.37079
134 3E5H GNP 3.37079
135 1XMV ADP 3.37079
136 4LX0 BEF GDP 3.38983
137 4QDI ATP 3.38983
138 4KVA GTP 3.39806
139 4BQS ADP 3.40909
140 4BQS K2Q 3.40909
141 2AWN ADP 3.41207
142 3EWA ANP 3.41615
143 4PX9 ADP 3.42466
144 1KO8 6PG 3.42857
145 5HCN GCP 3.44828
146 3CX8 GSP 3.44828
147 3WSJ MK1 3.44828
148 2FAH GDP 3.45395
149 6FA4 GNP 3.46821
150 4UTG ANP 3.46821
151 4IEE AGS 3.46939
152 3HU3 AGS 3.47648
153 5XDR ADP 3.47826
154 4OI4 ATP 3.47826
155 5ZXD ATP 3.47985
156 2GCO GNP 3.48259
157 2GCN GDP 3.48259
158 5LTJ ADP 3.5014
159 5LTJ BEF 3.5014
160 5WDR GNP 3.50877
161 2IYL GDP 3.52113
162 1G16 GDP 3.52941
163 5FG3 GDP 3.5313
164 1P3D ANP 3.57895
165 6D5L GNP 3.59281
166 6D59 GNP 3.59281
167 6D56 GNP 3.59281
168 6D55 GNP 3.59281
169 6D5E GNP 3.59281
170 6D5J GNP 3.59281
171 6D5M GNP 3.59281
172 6BVJ GNP 3.59281
173 6D5V GNP 3.59281
174 6D5G GNP 3.59281
175 6D5H GNP 3.59281
176 6BVL GNP 3.59281
177 6BVI GNP 3.59281
178 6BVK GNP 3.59281
179 6BVM GNP 3.59281
180 1CLU DBG 3.61446
181 1NVV GNP 3.61446
182 1AKY AP5 3.63636
183 2XTZ GSP 3.67232
184 1S3G AP5 3.68664
185 5FHD ADP ALF 3.69515
186 5FTB ANP 3.69515
187 1AQU A3P 3.7037
188 1H74 ADP 3.71622
189 1IWE IMP 3.71991
190 4A4Z ANP 3.75147
191 4PU5 ANP 3.75276
192 3VMF GTP 3.75335
193 2BME GNP 3.76344
194 5Z69 AGS 3.76344
195 4KFU ACP 3.77358
196 2FH5 GTP 3.78378
197 1M7G ADX 3.79147
198 1M7G AV2 3.79147
199 1M7G ADP 3.79147
200 1KMQ GNP 3.80435
201 4QRH 0O2 3.80952
202 3DEF GDP 3.81679
203 1OYY AGS 3.82409
204 3A4M ADP 3.84615
205 5W76 GDP 3.8961
206 1GWN GTP 3.90244
207 3B7G ANP 3.91304
208 1OE0 TTP 3.91304
209 1TKU 5RP 3.92157
210 4U5X GNP 3.93258
211 2JLR ANP 3.99113
212 2D2F ADP 4
213 5KSZ GCP 4.00943
214 2HT6 GDP 4.02299
215 1F0X FAD 4.02802
216 3FYH ADP 4.03727
217 1LVG ADP 4.0404
218 2A92 NAI 4.04984
219 2R42 FPS 4.05063
220 4R98 GNH 4.05904
221 3U6B GDP 4.06091
222 5JBQ GDP 4.06091
223 3U6K GDP 4.06091
224 4G5G GDP 4.06091
225 3AB3 GDP 4.06504
226 1D8T GDP 4.07125
227 2BVN GNP 4.07125
228 1OS1 PYR 4.07407
229 1OS1 ATP 4.07407
230 4PTN PYR 4.08163
231 1R6B ADP 4.08971
232 1DAR GDP 4.10317
233 1EK0 GNP 4.11765
234 1QF9 C5P 4.12371
235 1QF9 ADP 4.12371
236 1QF9 ALF 4.12371
237 1ZIN AP5 4.14747
238 3MJH GTP 4.16667
239 2DT9 THR 4.19162
240 3Q72 GNP 4.21687
241 4GOJ GNP 4.2328
242 1SVK ALF GDP 4.24929
243 4K81 GTP 4.26357
244 3ZFD ANP 4.2735
245 5W7Q GDP 4.28954
246 2OFW ADX 4.32692
247 4LH7 1X8 4.33437
248 5W75 SUC 4.33673
249 5W75 GDP 4.33673
250 1M7B GTP 4.34783
251 3AQ4 GDP 4.34783
252 4E03 ADP 4.36893
253 4IDN GNP 4.37637
254 4RZ3 ADP 4.40678
255 3W5J GDP 4.41176
256 1T8U A3P 4.41176
257 1T8U UAP SGN IDS SGN 4.41176
258 1FZQ GDP 4.41989
259 1UKZ ADP 4.4335
260 3RLF ANP 4.47368
261 2FNA ADP 4.48179
262 1FP6 ADP 4.49827
263 1SVM ATP 4.50928
264 3WXM GTP 4.52128
265 1Y3A GDP 4.55927
266 4PPF FLC 4.57143
267 1JI0 ATP 4.58333
268 4D81 ADP 4.59364
269 4MKG AP5 4.60829
270 4DKX GDP 4.62963
271 4GBM A3P 4.64396
272 1NN5 ANP 4.65116
273 1NN5 2DT 4.65116
274 2XAU ADP 4.65718
275 1RJ9 GCP 4.66667
276 5GVR LMR 4.70085
277 1Z08 GNP 4.70588
278 5V22 SAH 4.7138
279 2J0V GDP 4.71698
280 1G41 ADP 4.72973
281 1M2O GNP 4.73684
282 1G3M PCQ 4.7619
283 1G3M A3P 4.7619
284 1BH2 GSP 4.7619
285 2WJG GDP 4.78723
286 5AK0 8V1 4.80769
287 1O3Y GTP 4.81928
288 3BP1 GUN 4.82759
289 1VG8 GNP 4.83092
290 1VG0 GDP 4.83092
291 1RE0 GDP 4.87805
292 1N07 FMN 4.90798
293 1RYH GNP 4.92611
294 1ION ADP 4.93827
295 1B0U ATP 4.96183
296 3SFV GDP 4.97238
297 5JCP GDP ALF 5.01193
298 5JLB SAH 5.01792
299 2PEZ DAT 5.02793
300 2PEZ GGZ 5.02793
301 2RCN GDP 5.02793
302 4BFW ZVW 5.03145
303 4FMU 0UM 5.03597
304 1WQ1 GDP 5.08982
305 5XC5 GTP 5.11364
306 1J99 AND 5.11945
307 4TL6 ANP 5.13834
308 2ZE7 DST 5.13834
309 2ZE7 AMP 5.13834
310 4X8O AP5 5.14019
311 5E95 GDP 5.15464
312 1T5C ADP 5.15759
313 6FAA ADP 5.19084
314 1E96 GTP 5.20833
315 1I4D GDP 5.20833
316 4HSE ADP 5.28967
317 1R2Q GNP 5.29412
318 3RAB GNP 5.32544
319 3SBD GNP 5.34759
320 4D0N GDP 5.36193
321 1MH1 GNP 5.37634
322 3CPJ GDP 5.38117
323 4NON GDP 5.38462
324 4LAE NAP 5.38922
325 4LAE 1VM 5.38922
326 3W9F I3P 5.39273
327 1VG1 GDP 5.40541
328 1VG9 GDP 5.40541
329 2WJH GDP 5.42169
330 2WJH FLC 5.42169
331 2QEN ADP 5.42857
332 2Q2Y MKR 5.44959
333 2Q2Y ADP 5.44959
334 2CBZ ATP 5.48523
335 1D2N ANP 5.51471
336 4NU0 AP5 5.52995
337 3NHB ADP 5.55556
338 1TX4 ALF GDP 5.55556
339 3N5C GDP 5.55556
340 1NJF AGS 5.6
341 1NJF ADP 5.6
342 1KK1 GNP 5.60976
343 2FJU GSP 5.61798
344 1WF3 GNP 5.64784
345 1NY5 ADP 5.68475
346 2Z5F A3P 5.7047
347 4M9Q GNP 5.72687
348 1EYN 2AN 5.72792
349 5K5Z ANP 5.73248
350 1G6O ADP 5.75758
351 4J0Q GDP 5.77367
352 4WOP CTP 5.77778
353 1OW3 GDP 5.78512
354 5KSP GDP 5.78947
355 1ZRH A3P 5.83942
356 1NST A3P 5.84615
357 3FVQ ATP 5.84958
358 4DCT GDP 5.92105
359 1OXV ANP 5.94901
360 4PFO ADP 5.96447
361 5J1J ANP 5.96491
362 1Y63 ADP 5.97826
363 4MKF AP5 5.99078
364 3UIE ANP 6
365 1WUU ANP 6.01504
366 3TMK T5A 6.01852
367 5HR5 ADP 6.02637
368 5VGR GDP 6.03248
369 5HPY GDP 6.03448
370 5YT0 GDP 6.04396
371 1W5T ANP 6.06796
372 1W5T ADP 6.06796
373 2C9O ADP 6.14035
374 3IUY AMP 6.14035
375 5BN3 ADP 6.14035
376 3PCR GTP 6.17284
377 6A20 ADP 6.17849
378 2A2C ADP 6.27615
379 2A2C NG1 6.27615
380 2A5J GDP 6.28272
381 4HUT ATP 6.28272
382 5LB3 ADP 6.29213
383 1GQY ACP 6.31579
384 3TNF GNP 6.32184
385 4LHW GNP 6.32184
386 2JAQ DCP 6.34146
387 1V8K ANP 6.34146
388 4ITM ATP 6.34921
389 6AU6 GDP 6.36605
390 1U0J ADP 6.36704
391 2ZTS ADP 6.3745
392 4GOX A3P 6.38978
393 2OG2 MLI 6.40669
394 2ZPA ADP 6.40835
395 5E5U MLI 6.43939
396 4PJ3 ANP 6.44783
397 3VX3 ADP 6.45161
398 1TAD GDP 6.48148
399 1TAD ALF 6.48148
400 4BAS GNP 6.53266
401 1KAO GDP 6.58683
402 5UIV ADP 6.60793
403 1W7J ADP BEF 6.62252
404 3ZL8 ADP 6.63616
405 2CHG ANP 6.63717
406 2YOH WMJ 6.66667
407 6BC0 GSP 6.66667
408 1HEX NAD 6.66667
409 5TIV A3P 6.71937
410 6BSX GDP 6.74157
411 6BSX E7S 6.74157
412 3DDC GNP 6.74847
413 1OFH ADP 6.77419
414 1JBW ACQ 6.7757
415 1S8F GDP 6.77966
416 5MVR ADP 6.79012
417 2Y65 ADP 6.84932
418 2DPY ADP 6.84932
419 2ZR9 DTP 6.87679
420 3R96 AMP 6.91489
421 3R96 ACO 6.91489
422 3DKP ADP 6.93878
423 1E2K TMC 6.94864
424 3FKQ ATP 6.97051
425 5DI3 GNP 7.02703
426 5JCZ GDP 7.0529
427 5H68 AGS 7.05882
428 4XVU ATP 7.06215
429 2WOJ ADP ALF 7.06215
430 4XTR ATP 7.06215
431 4XTR ADP 7.06215
432 3DZD ADP 7.06522
433 3T12 GDP ALF 7.07071
434 3T1O GDP 7.07071
435 4Q1A 2XZ 7.14286
436 4Q1A UDP 7.14286
437 1S7N COA 7.14286
438 5IFS ADP 7.173
439 5G41 AP5 7.17489
440 2B8T THM 7.17489
441 4R43 GDP 7.1885
442 3GJ4 GDP 7.23982
443 3GJ0 GDP 7.23982
444 3GJ3 GDP 7.23982
445 3GJ5 GDP 7.23982
446 4C5N ACP 7.24638
447 4C5N PXL 7.24638
448 2XTN GTP 7.26496
449 1Z6T ADP 7.2758
450 1MKY GDP 7.28929
451 3WYF GTP 7.30594
452 4U00 ADP 7.37705
453 3FB4 AP5 7.40741
454 1IBR GNP 7.40741
455 3GJX GTP 7.40741
456 5BXQ GDP 7.40741
457 2CDN ADP 7.46269
458 1Z0A GDP 7.47126
459 1FQK GDP 7.48299
460 5L3R GCP 7.50853
461 6H5E ANP 7.56972
462 1G3Q ADP 7.59494
463 2ZEJ GDP 7.6087
464 3B9Q MLI 7.61589
465 3E70 GDP 7.62195
466 5OEC GDP 7.65027
467 4ZDJ UTP 7.6661
468 1Q20 PLO 7.69231
469 1Q20 A3P 7.69231
470 1YTM ATP 7.70677
471 1ZUI SKM 7.7381
472 5H4S RAM 7.74648
473 3A1S GDP 7.75194
474 2A5F GTP 7.77202
475 1DS6 GDP 7.77778
476 2CJW GDP 7.8125
477 3FSY SCA 7.83133
478 3EC1 GDP 7.85908
479 5Z2M GTP 7.97101
480 1BG2 ADP 8
481 2R3A SAM 8
482 4KAX GTP 8.07453
483 2G77 GDP 8.08081
484 5WC2 ADP 8.10185
485 3RWO GDP 8.10811
486 1F2U ATP 8.10811
487 2HCJ GDP 8.10811
488 2ORV 4TA 8.11966
489 5X40 ACP 8.21918
490 2RGX AP5 8.25243
491 1U8Z GDP 8.33333
492 3IIJ ADP 8.33333
493 4OHY ANP 8.35267
494 1S9D GDP 8.37438
495 1Z0F GDP 8.37989
496 2QZ4 ADP 8.39695
497 5G3Y ADP 8.40708
498 3V2U ATP 8.44749
499 5KUT GDP 8.46561
500 3EZ2 ADP 8.54271
501 1F6B GDP 8.58586
502 4YLG GDP 8.67052
503 4D0G GTP 8.69565
504 1JJV ATP 8.73786
505 2ZFI ADP 8.74317
506 1YRB GDP 8.77863
507 3WYG GTP 8.79121
508 2EFE GNH 8.83978
509 1ZC3 GNP 8.84956
510 6BCB GSP 8.90411
511 2J59 GTP 8.92857
512 5IRC GDP 8.95522
513 2D7C GTP 8.98204
514 2X77 GDP 8.99471
515 5L3V GDP 9.0301
516 5L3S GNP 9.0604
517 1WA5 GTP 9.09091
518 4TQK NAG 9.1133
519 1G4U GDP 9.13838
520 3CNL GNP 9.16031
521 3GJ7 GDP 9.18367
522 6B8B ADP 9.23695
523 4V03 ADP 9.33852
524 2BEK ATP 9.33852
525 2C5L GTP 9.40171
526 3QKT ANP 9.43953
527 3Q85 GNP 9.46746
528 3H4S ADP 9.58549
529 4FRZ ADP 9.58549
530 2UZI GTP 9.61539
531 4YDS ATP 9.64912
532 2W2X GSP 9.67742
533 1W4R TTP 9.74359
534 5EP2 AZU 9.76562
535 1DAK DPU 9.82143
536 1DAK ADP 9.82143
537 3LRE ADP 9.85915
538 1GP2 GDP 9.85915
539 6CRK GDP 9.85915
540 1W0J ADP BEF 9.92647
541 1W0J ADP 9.92647
542 1OIV GDP 9.94764
543 1OIX GDP 9.94764
544 3QBT GNP 10
545 4IOK ADP 10.0179
546 4IOK XPO 10.0179
547 3NOJ PYR 10.084
548 4KVG GTP 10.119
549 1L2T ATP 10.2128
550 3REF GDP 10.3093
551 5WRI A3P 10.3125
552 1UJ2 ADP 10.3175
553 1UJ2 C5P 10.3175
554 2IXE ATP 10.3321
555 1ZX5 LFR 10.3333
556 5SZH GNP 10.3448
557 2O66 FLC 10.3704
558 5J1S ATP 10.5691
559 2ODE ALF GDP 10.6383
560 1G7C 5GP 10.6383
561 3X1Z GNP 10.7784
562 5WRJ A3P 10.8911
563 4PC3 GDP 10.9929
564 2KIN ADP 11
565 1NRJ GTP 11.0092
566 1KSH GDP 11.1842
567 3T5G GDP 11.1842
568 5UWH GNP 11.1888
569 6CIT GNP 11.1888
570 5UWS GNP 11.1888
571 5UWU GNP 11.1888
572 5UWP GNP 11.1888
573 5UWQ GNP 11.1888
574 5DIF GNP 11.1888
575 5UWJ GNP 11.1888
576 5DI9 GNP 11.1888
577 1SVI GDP 11.2821
578 4QOS ADP 11.3208
579 2GWH A3P 11.4094
580 4HAT GNP 11.4286
581 2V2V V12 11.4391
582 2EW1 GNP 11.4428
583 3QXC ATP 11.5702
584 4TMK T5A 11.7371
585 5GQI CTP 11.7409
586 1R4A GNP 11.7647
587 3KJI ADP 11.811
588 1T3Q MCN 11.9048
589 3DOE GTP 11.9792
590 1XEX ATP 12.0879
591 3KTA AP5 12.0879
592 5LLB 6YZ 12.1673
593 5O74 GDP 12.2222
594 2D7D ADP 12.5
595 2QQ0 TMP 12.5
596 2QQ0 ADP 12.5
597 2QQ0 ANP 12.5
598 2QQ0 THM 12.5
599 2GDJ ANP 12.5
600 3NKV GNP 12.5714
601 1HE1 GDP 12.5926
602 3ZIA ATP 12.6984
603 3ZIA ADP 12.6984
604 2WIC GNP 12.7341
605 4XSH GSP 12.7854
606 3PQC GDP 12.8205
607 3LXR GDP 13.0208
608 4TTQ ATP 13.0233
609 1Z2A GDP 13.0952
610 5ZB0 ADP 13.1313
611 5ZB0 TYD 13.1313
612 4HDO GNP 13.1737
613 4HDQ GNP 13.1737
614 1CS4 GSP 13.2075
615 6BCA GSP 13.245
616 1MR3 G3D 13.2597
617 5YVT NAI 13.2768
618 2FFQ GSP 13.4503
619 4HI0 GDP 13.5678
620 4CVN ADP 13.6126
621 1G6H ADP 13.6187
622 1Z83 AP5 13.7755
623 1ZJ6 G3D 13.9037
624 2GJ8 ALF GDP 13.9535
625 1YZG GDP 13.9665
626 2QTV GNP 14.2857
627 3R5J ACE ALA ASP VAL ALA ASA 14.2857
628 1ZD9 GDP 14.3617
629 3ZQ6 ADP ALF 14.5062
630 3M1I GTP 14.6597
631 1CXZ GSP 15.1163
632 5UPK GNP 15.1351
633 1XX6 ADP 15.1832
634 2PL3 ADP 15.2542
635 1RRC ADP 15.2824
636 1NF3 GNP 15.3846
637 3Q9L ATP 15.3846
638 2BCG GDP 15.534
639 4DID GDP 15.544
640 5N69 ADP 15.5779
641 1A4R GDP 15.7068
642 1A4R GNH 15.7068
643 4ITR GDP 15.7068
644 2NGR GDP 15.7068
645 1GRN GDP 15.7068
646 2WMO GTP 15.7895
647 4YC7 GNP 16.0221
648 2A9K GDP 16.0428
649 3KUD GDP 16.0494
650 1GUA GNP 16.0494
651 2VB6 ADP BEF 16.1074
652 3TKL GTP 16.3265
653 1JJ7 ADP 16.5385
654 2DTJ THR 16.8539
655 3AB4 THR 16.8539
656 3BC1 GNP 16.9492
657 1UAD GNP 17.1717
658 1YZN GNP 17.2973
659 4FCW ADP 17.3633
660 1B7T ADP 17.9487
661 1KY3 GDP 18.1319
662 1KK8 BEF ADP 18.1818
663 1LFD GNP 18.3908
664 3GJ8 GDP 18.4783
665 5UWR GNP 18.5185
666 3B5J 12D 18.5185
667 4WZ6 ATP 18.6207
668 2Y8E GNP 19.5531
669 5EE5 GTP 19.883
670 3QF7 ANP 20
671 1NXJ GLV 20.2186
672 1HTW ADP 20.2532
673 1Z0K GTP 20.2899
674 4ZI2 GNP 20.3008
675 2W83 GTP 20.7792
676 1YZQ GNP 21.1765
677 4P3Y GDP 21.4286
678 3WY9 GDP 21.875
679 1Z0J GTP 22.0339
680 4QM7 GTP 22.2222
681 4C4P GNP 22.4299
682 3BER AMP 22.49
683 5LEF GTP 22.7273
684 2OZE AGS 22.8188
685 5U32 GDP 22.8814
686 4XOI GTP 22.963
687 5KDO GDP 22.973
688 1GOT GDP 23.2877
689 2HV8 GTP 23.4375
690 5UWW GNP 23.8095
691 1FQJ GDP 23.8095
692 6AIC AMP 23.8318
693 2PZE ATP 24.4541
694 1VHT BA3 28.4404
695 2OM2 GDP 30.5556
696 1QHH ATP 32.1739
697 6C90 ADP 32.6923
698 3CH5 GDP 34.6154
699 5WLB GNP 35.2941
700 3ZS9 ADP ALF 36.8421
701 5UWT GNP 39.1304
702 1J2J GTP 40
703 2V7Q ATP 40
704 2CK3 ADP 40
705 2V7Q ADP 40
706 2CK3 ANP 40
707 2QN6 GDP 44.086
708 5UWI GNP 44.4444
709 5UWO GNP 50
Pocket No.: 2; Query (leader) PDB : 2FSH; Ligand: ANP; Similar sites found with APoc: 41
This union binding pocket(no: 2) in the query (biounit: 2fsh.bio1) has 14 residues
No: Leader PDB Ligand Sequence Similarity
1 2IVD FAD 1.25523
2 1D8C GLV 1.93638
3 1JQN DCO 1.99297
4 4YJ1 ADP 2.11382
5 2RL1 UD1 2.35849
6 3LL4 2FP 2.39726
7 6A5K SAM 2.46679
8 2AJ4 ANP 2.55474
9 2FY3 CHT 2.61438
10 2JJK R15 2.66272
11 3A9B CBI 2.78481
12 3UN3 G16 3.00752
13 4HVA 4HV 3.01887
14 5EB4 FAD 3.19549
15 1WNG SAH 3.39623
16 5TPR NAD 3.6036
17 6BOX SAH 3.63036
18 1O2D NAP 4.04313
19 1VHD NAP 4.04313
20 5YPU ATP 4.34783
21 1VQ2 DDN 4.66321
22 5IF4 6AK 5.03145
23 4U8P UDP 5.06823
24 3MWL 8OX 5.31401
25 3AKK ADP 5.53846
26 1YRO GDU 5.69106
27 2OKL BB2 5.94595
28 1N62 MCN 6.94444
29 4HCX NDP 7.57946
30 4Y7U 2KH 8.65801
31 3RC3 ANP 9.01034
32 3H8V ATP 9.58904
33 4Z4P SAH 11.4458
34 4JLV ADP 11.5242
35 5NWD 9C8 12.0419
36 1I1D 16G 12.4224
37 1RC0 KT5 13.3971
38 1CTU ZEB 15.3061
39 1YC5 NCA 16.6667
40 2B3D FAD 16.6667
41 5NM7 GLY 17.6692
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