Receptor
PDB id Resolution Class Description Source Keywords
2FHK 2 Å EC: 2.3.1.101 CRYSTAL STRUCTURE OF FORMYLMETHANOFURAN: TETRAHYDROMETHANOPTERIN FORMYLTRANSFERASE IN COMPLEX WITH I TS COENZYMES METHANOPYRUS KANDLERI TETRAHYDROMETHANOPTERIN; METHANOFURAN; C1 METABOLISM; FORMYLTRANSFERASE; COMPLEX
Ref.: THE STRUCTURE OF FORMYLMETHANOFURAN: TETRAHYDROMETHANOPTERIN FORMYLTRANSFERASE IN COMPLEX WITH ITS COENZYMES J.MOL.BIOL. V. 357 870 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
K A:701;
A:708;
A:711;
A:716;
B:704;
B:706;
B:709;
B:713;
B:717;
C:702;
C:705;
C:710;
C:714;
D:703;
D:707;
D:712;
D:715;
D:718;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
39.098 K [K+]
MFN A:600;
B:602;
C:601;
Valid;
Valid;
Valid;
none;
none;
none;
submit data
776.741 C35 H44 N4 O16 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2FHK 2 Å EC: 2.3.1.101 CRYSTAL STRUCTURE OF FORMYLMETHANOFURAN: TETRAHYDROMETHANOPTERIN FORMYLTRANSFERASE IN COMPLEX WITH I TS COENZYMES METHANOPYRUS KANDLERI TETRAHYDROMETHANOPTERIN; METHANOFURAN; C1 METABOLISM; FORMYLTRANSFERASE; COMPLEX
Ref.: THE STRUCTURE OF FORMYLMETHANOFURAN: TETRAHYDROMETHANOPTERIN FORMYLTRANSFERASE IN COMPLEX WITH ITS COENZYMES J.MOL.BIOL. V. 357 870 2006
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2FHK - MFN C35 H44 N4 O16 c1cc(ccc1C....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2FHK - MFN C35 H44 N4 O16 c1cc(ccc1C....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2FHK - MFN C35 H44 N4 O16 c1cc(ccc1C....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: MFN; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 MFN 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: MFN; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2FHK; Ligand: MFN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2fhk.bio1) has 21 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 2FHK; Ligand: MFN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2fhk.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 2FHK; Ligand: MFN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 2fhk.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
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