Receptor
PDB id Resolution Class Description Source Keywords
2F3R 2.5 Å EC: 2.7.4.8 CRYSTAL STRUCTURE OF E.COLI GUANYLATE KINASE IN COMPLEX WITH ESCHERICHIA COLI TRANSFERASE GMP KINASE GUANYLATE KINASE NUCLEOTIDE ANALOG
Ref.: CRYSTAL STRUCTURES OF GMP KINASE IN COMPLEX WITH GA MONOPHOSPHATE AND AP5G. BIOCHIMIE V. 88 1157 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
G5P A:601;
B:602;
Valid;
Valid;
none;
none;
ic50 = 0.5 uM
932.366 C20 H29 N10 O23 P5 c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2F3R 2.5 Å EC: 2.7.4.8 CRYSTAL STRUCTURE OF E.COLI GUANYLATE KINASE IN COMPLEX WITH ESCHERICHIA COLI TRANSFERASE GMP KINASE GUANYLATE KINASE NUCLEOTIDE ANALOG
Ref.: CRYSTAL STRUCTURES OF GMP KINASE IN COMPLEX WITH GA MONOPHOSPHATE AND AP5G. BIOCHIMIE V. 88 1157 2006
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 2F3R ic50 = 0.5 uM G5P C20 H29 N10 O23 P5 c1nc(c2c(n....
2 2AN9 - GMP C10 H13 N5 O5 c1nc2c(n1[....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 2F3R ic50 = 0.5 uM G5P C20 H29 N10 O23 P5 c1nc(c2c(n....
2 2AN9 - GMP C10 H13 N5 O5 c1nc2c(n1[....
50% Homology Family (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1EX7 - 5GP C10 H14 N5 O8 P c1nc2c(n1[....
2 1GKY - 5GP C10 H14 N5 O8 P c1nc2c(n1[....
3 2F3R ic50 = 0.5 uM G5P C20 H29 N10 O23 P5 c1nc(c2c(n....
4 2AN9 - GMP C10 H13 N5 O5 c1nc2c(n1[....
5 1LVG - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
6 1ZNY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 1ZNX - 5GP C10 H14 N5 O8 P c1nc2c(n1[....
8 1ZNZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
9 4QRH Ki = 7 uM 0O2 C10 H18 N5 O20 P5 c1nc2c(n1[....
10 2J41 - 5GP C10 H14 N5 O8 P c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: G5P; Similar ligands found: 336
No: Ligand ECFP6 Tc MDL keys Tc
1 G5P 1 1
2 G3A 0.988889 1
3 GP3 0.788889 1
4 GTP 0.755319 0.973684
5 GDP 0.723404 0.973684
6 B4P 0.722222 0.921053
7 AP5 0.722222 0.921053
8 GSP 0.721649 0.925
9 BA3 0.711111 0.921053
10 GNH 0.697917 0.961039
11 GCP 0.693878 0.948718
12 G1R 0.693878 0.961039
13 GTA 0.691589 0.962025
14 AQP 0.691489 0.921053
15 5FA 0.691489 0.921053
16 GNP 0.686869 0.948718
17 G A A A 0.684211 0.948718
18 ATP 0.680851 0.921053
19 U A G G 0.678261 0.961039
20 A2D 0.67033 0.921053
21 5GP 0.670213 0.960526
22 G 0.670213 0.960526
23 GTG 0.663551 0.962025
24 GDC 0.654206 0.961538
25 GDD 0.654206 0.961538
26 GKE 0.654206 0.961538
27 G2R 0.653846 0.936709
28 GMV 0.65 0.948718
29 AGS 0.649485 0.875
30 SAP 0.649485 0.875
31 ADP 0.648936 0.921053
32 GAV 0.640777 0.936709
33 G2P 0.637255 0.936709
34 GP2 0.636364 0.936709
35 ANP 0.636364 0.897436
36 A4P 0.626087 0.892857
37 AN2 0.625 0.909091
38 Y9Z 0.623853 0.880952
39 AR6 0.622449 0.896104
40 APR 0.622449 0.896104
41 ACQ 0.62 0.897436
42 M33 0.618557 0.884615
43 GFB 0.618182 0.961538
44 GDR 0.618182 0.961538
45 GPG 0.616822 0.987013
46 AD9 0.616162 0.897436
47 GKD 0.616071 0.961538
48 UP5 0.614035 0.898734
49 6CK 0.612613 0.9375
50 ACP 0.612245 0.897436
51 GDP MG 0.607843 0.9
52 CA0 0.602041 0.897436
53 GDP BEF 0.601942 0.878049
54 ALF 5GP 0.601942 0.86747
55 JB2 0.60177 0.961538
56 YGP 0.6 0.902439
57 GDX 0.596491 0.974026
58 GPD 0.596491 0.925926
59 A1R 0.59434 0.841463
60 GCP G 0.59434 0.911392
61 ATF 0.592233 0.886076
62 CAG 0.590164 0.904762
63 T5A 0.588235 0.825581
64 ADX 0.585859 0.811765
65 APC G U 0.585366 0.911392
66 A 0.585106 0.894737
67 AMP 0.585106 0.894737
68 GTP MG 0.584906 0.9
69 BEF GDP 0.584906 0.86747
70 JB3 0.584746 0.949367
71 GDP AF3 0.583333 0.86747
72 U G A 0.58209 0.91358
73 25L 0.581818 0.934211
74 50T 0.58 0.884615
75 ADQ 0.579439 0.897436
76 A22 0.575472 0.934211
77 TPG 0.574803 0.842697
78 PRX 0.574257 0.82716
79 TAT 0.572816 0.886076
80 0O2 0.572727 0.960526
81 GDP ALF 0.568807 0.86747
82 5AL 0.567308 0.884615
83 ABM 0.56701 0.848101
84 NGD 0.566667 0.987013
85 2MD 0.565574 0.892857
86 4AD 0.564815 0.875
87 APC 0.558824 0.886076
88 AMP MG 0.556701 0.825
89 SRP 0.556604 0.8625
90 AP2 0.555556 0.886076
91 8QN 0.555556 0.884615
92 A12 0.555556 0.886076
93 OAD 0.554545 0.897436
94 GMP 0.553191 0.857143
95 MGD 0.552 0.892857
96 4TC 0.55 0.876543
97 SRA 0.546392 0.85
98 MAP 0.546296 0.875
99 G3D 0.546296 0.960526
100 00A 0.545455 0.864198
101 BIS 0.544643 0.864198
102 3OD 0.544643 0.897436
103 OOB 0.541284 0.909091
104 5SV 0.541284 0.788235
105 U2G 0.540984 0.9375
106 FEG 0.540984 0.903614
107 G G 0.539823 0.961039
108 AU1 0.539216 0.897436
109 ADP MG 0.539216 0.8375
110 ZGP 0.536585 0.892857
111 139 0.536585 0.855422
112 AMO 0.536364 0.886076
113 G4P 0.536364 0.960526
114 PAJ 0.536364 0.843373
115 PR8 0.535714 0.811765
116 LAD 0.535714 0.821429
117 WAQ 0.535714 0.841463
118 4BW 0.534483 0.947368
119 1YD 0.534483 0.947368
120 BEF ADP 0.533981 0.817073
121 ADP BEF 0.533981 0.817073
122 CG2 0.532258 0.9375
123 DLL 0.531532 0.909091
124 1ZZ 0.530973 0.802326
125 A G U 0.528986 0.91358
126 GH3 0.527273 0.948052
127 25A 0.527273 0.921053
128 3UK 0.526786 0.922078
129 GDP 7MG 0.525424 0.936709
130 UPA 0.52459 0.8875
131 7D4 0.524272 0.8375
132 RBY 0.52381 0.8625
133 ADP PO3 0.52381 0.87013
134 ADV 0.52381 0.8625
135 MD1 0.523077 0.892857
136 PGD 0.523077 0.925926
137 9SN 0.521739 0.876543
138 4UV 0.521368 0.875
139 DND 0.520661 0.910256
140 NXX 0.520661 0.910256
141 ATP MG 0.518868 0.8375
142 AHX 0.517857 0.853659
143 PTJ 0.517544 0.853659
144 TXA 0.517544 0.886076
145 ME8 0.517544 0.802326
146 NB8 0.517544 0.853659
147 TXE 0.516393 0.8875
148 FE9 0.515385 0.778947
149 AFH 0.512605 0.843373
150 4UU 0.512605 0.875
151 ITT 0.509615 0.87013
152 DGT 0.509091 0.9
153 4UW 0.508197 0.843373
154 TXD 0.508197 0.8875
155 3GP 0.504854 0.922078
156 ALF ADP 0.504587 0.807229
157 ADP ALF 0.504587 0.807229
158 FYA 0.504348 0.860759
159 YAP 0.504274 0.875
160 FA5 0.504274 0.886076
161 OMR 0.504065 0.813953
162 G1R G1R 0.503759 0.949367
163 DBG 0.503759 0.974359
164 GAP 0.5 0.85
165 YLP 0.5 0.784091
166 48N 0.5 0.9
167 G4M 0.5 0.904762
168 ANP MG 0.5 0.829268
169 SON 0.5 0.886076
170 ADP VO4 0.5 0.860759
171 VO4 ADP 0.5 0.860759
172 NAX 0.495935 0.855422
173 NAI 0.495935 0.8875
174 6V0 0.495935 0.876543
175 JBT 0.494186 0.8
176 ADJ 0.488189 0.813953
177 YLC 0.488 0.802326
178 AP0 0.488 0.853659
179 YLB 0.488 0.784091
180 XAH 0.487395 0.802326
181 6G0 0.486486 0.936709
182 2A5 0.485981 0.85
183 7D3 0.485437 0.8375
184 G1G 0.484848 0.95
185 CNA 0.484375 0.910256
186 4UR 0.484127 0.947368
187 PAP 0.481481 0.907895
188 ATR 0.481481 0.894737
189 TYM 0.48 0.886076
190 LAQ 0.479675 0.802326
191 1YC 0.479339 0.921053
192 GPX 0.478261 0.922078
193 DAL AMP 0.477876 0.860759
194 MGP 0.477477 0.936709
195 I2C FE2 CMO CMO 0.477273 0.811111
196 NAD 0.476923 0.909091
197 YLA 0.476562 0.784091
198 2GP 0.47619 0.935065
199 ADP BMA 0.474138 0.873418
200 AYB 0.472868 0.775281
201 DGI 0.472727 0.9
202 3AT 0.472727 0.896104
203 A A 0.470085 0.896104
204 A3D 0.469697 0.897436
205 A2R 0.469027 0.909091
206 IOT 0.46875 0.858824
207 IDP 0.46789 0.947368
208 JB6 0.466102 0.841463
209 AOC 0.466019 0.759494
210 COD 0.465649 0.777778
211 5AS 0.462264 0.728261
212 MYR AMP 0.462185 0.781609
213 BT5 0.462121 0.795455
214 YLY 0.459259 0.775281
215 FDA 0.458333 0.83908
216 ADN 0.457447 0.779221
217 RAB 0.457447 0.779221
218 XYA 0.457447 0.779221
219 BGO 0.457364 0.949367
220 PGD O 0.456522 0.852273
221 7C5 0.455285 0.896104
222 6FA 0.455172 0.891566
223 BTX 0.454545 0.804598
224 4TA 0.454545 0.793103
225 ATP A A A 0.454545 0.883117
226 EAD 0.453237 0.855422
227 AR6 AR6 0.451613 0.871795
228 N0B 0.449275 0.804598
229 ZID 0.449275 0.922078
230 FAS 0.44898 0.902439
231 FAD 0.44898 0.902439
232 M24 0.448529 0.855422
233 5N5 0.447917 0.75641
234 GGM 0.44697 0.925926
235 DTP 0.446429 0.8375
236 7D5 0.445545 0.8125
237 P1G 0.445455 0.85
238 NAE 0.445255 0.898734
239 EP4 0.444444 0.698795
240 AHZ 0.444444 0.802326
241 FAY 0.443709 0.91358
242 5CD 0.443299 0.74359
243 A4D 0.443299 0.75641
244 6AD 0.442478 0.843373
245 NAQ 0.442029 0.876543
246 ARU 0.440678 0.8
247 P1H 0.440559 0.835294
248 P2G 0.440367 0.860759
249 7MD 0.44 0.823529
250 TSB 0.439655 0.784091
251 A3P 0.439252 0.894737
252 SFD 0.439189 0.778947
253 TYR AMP 0.439024 0.8625
254 G5A 0.4375 0.747253
255 NA7 0.436975 0.886076
256 3AM 0.436893 0.857143
257 TAD 0.436508 0.843373
258 G G U 0.436508 0.961039
259 AMP DBH 0.435484 0.873418
260 SSA 0.434783 0.766667
261 AF3 ADP 3PG 0.434109 0.8
262 DDS 0.433628 0.8125
263 P5A 0.433333 0.715789
264 ARG AMP 0.433071 0.857143
265 RFL 0.431373 0.870588
266 DG 0.431193 0.8875
267 DGP 0.431193 0.8875
268 54H 0.431034 0.755556
269 VMS 0.431034 0.755556
270 PPS 0.429825 0.811765
271 FNK 0.427632 0.811111
272 3DH 0.427184 0.716049
273 GPC 0.426471 0.880952
274 128 0.426357 0.784091
275 AV2 0.426087 0.848101
276 A5A 0.426087 0.772727
277 A2P 0.425926 0.881579
278 MAO 0.425926 0.707865
279 DTA 0.425743 0.75
280 M2T 0.425743 0.682353
281 Z5A 0.425532 0.786517
282 ODP 0.425373 0.936709
283 G C 0.425373 0.901235
284 NAD IBO 0.425373 0.851852
285 FB0 0.424658 0.771739
286 NDC 0.424658 0.876543
287 AVV 0.423729 0.831325
288 NAJ PZO 0.423358 0.831325
289 ALF ADP 3PG 0.423077 0.8
290 LA8 ALF 3PG 0.423077 0.8
291 IMP 0.422018 0.934211
292 MTA 0.421569 0.716049
293 V3L 0.421053 0.896104
294 NDE 0.42069 0.935065
295 NSS 0.420168 0.766667
296 7MC 0.419847 0.804598
297 7DT 0.419643 0.907895
298 RGT 0.419355 0.910256
299 DZD 0.419118 0.865854
300 52H 0.418803 0.747253
301 LPA AMP 0.418605 0.781609
302 PUA 0.417266 0.865854
303 APU 0.416667 0.875
304 5CA 0.415254 0.766667
305 53H 0.415254 0.747253
306 P5F 0.415094 0.872093
307 6RE 0.415094 0.768293
308 NJP 0.414815 0.923077
309 G2Q 0.413223 0.936709
310 LEU LMS 0.413223 0.731183
311 NAJ PYZ 0.411348 0.833333
312 DAT 0.410714 0.8375
313 AMP NAD 0.408451 0.8625
314 LSS 0.408333 0.731183
315 DSZ 0.408333 0.766667
316 01G 0.408 0.903614
317 IMO 0.407407 0.857143
318 A3N 0.407407 0.728395
319 J7C 0.407407 0.777778
320 A U 0.406015 0.851852
321 ZAS 0.40566 0.731707
322 G7M 0.405405 0.924051
323 NVA LMS 0.404959 0.731183
324 S4M 0.40367 0.623656
325 GJV 0.40367 0.759036
326 SA8 0.403509 0.678161
327 OVE 0.401869 0.8375
328 SGP 0.401786 0.807229
329 MHZ 0.401786 0.652174
330 0WD 0.40146 0.9
331 F2N 0.401235 0.820225
332 C2E 0.4 0.947368
333 2AM 0.4 0.87013
334 PCG 0.4 0.934211
335 35G 0.4 0.934211
336 J1A 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2F3R; Ligand: G5P; Similar sites found: 286
This union binding pocket(no: 1) in the query (biounit: 2f3r.bio1) has 33 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1SS4 CIT 0.006186 0.48051 None
2 3KPE TM3 0.002397 0.47455 None
3 3NGU ADP 0.0004826 0.47097 None
4 4JCA CIT 0.01212 0.46666 None
5 2X77 GDP 0.002734 0.4522 None
6 3AQ4 GDP 0.003944 0.44432 None
7 3N5C GDP 0.004857 0.44431 None
8 1SS4 GSH 0.03661 0.4407 None
9 1UO4 PIH 0.03863 0.43768 None
10 3CNL GNP 0.01048 0.43169 None
11 3H86 AP5 0.000006254 0.42681 None
12 3RF4 FUN 0.01871 0.42097 None
13 1ECM TSA 0.03637 0.40357 None
14 3U6B GDP 0.01967 0.4174 1.26904
15 4G5G GDP 0.01879 0.41442 1.26904
16 3U6K GDP 0.03143 0.40297 1.26904
17 1D8T GDP 0.01613 0.41781 1.27226
18 3B5J 12D 0.002319 0.47126 1.44928
19 2JBH 5GP 0.0132 0.4235 1.44928
20 3CI3 5AD 0.001287 0.41002 1.54639
21 3CI3 3PO 0.001287 0.41002 1.54639
22 3F81 STT 0.01861 0.44864 1.63934
23 4A8H PUW 0.0004019 0.42126 1.93237
24 4CCO OGA 0.04111 0.40497 1.93237
25 4QCK ASD 0.0035 0.40444 1.93237
26 2BII MTV 0.005462 0.40357 1.93237
27 4E03 ADP 0.003846 0.44486 1.94175
28 2V57 PRL 0.04769 0.40138 2.10526
29 1C1L GAL BGC 0.01243 0.44509 2.18978
30 1FZQ GDP 0.003849 0.44943 2.20994
31 4TTQ ATP 0.005707 0.44076 2.41546
32 2FEQ 34P 0.001851 0.43825 2.41546
33 2A2X NA9 0.003417 0.42406 2.41546
34 3WY9 GDP 0.0165 0.4214 2.41546
35 1H0C AOA 0.04334 0.4172 2.41546
36 2C5S AMP 0.02219 0.41331 2.41546
37 1G8S MET 0.04249 0.41283 2.41546
38 3HZS M0E 0.000008728 0.41041 2.41546
39 3WYA GDP 0.02476 0.40829 2.41546
40 1RYH GNP 0.01838 0.40755 2.46305
41 3LRE ADP 0.0003747 0.51483 2.89855
42 1GOJ ADP 0.0003746 0.51467 2.89855
43 1A8S PPI 0.0005302 0.47732 2.89855
44 3DC4 ADP 0.002193 0.47255 2.89855
45 2J5S KTA 0.0008545 0.44711 2.89855
46 2GN2 C5P 0.001254 0.44489 2.89855
47 1O9U ADZ 0.02641 0.44024 2.89855
48 2ZFI ADP 0.007155 0.43577 2.89855
49 4J0Q GDP 0.01095 0.43069 2.89855
50 1V8K ANP 0.009898 0.42861 2.89855
51 4NTX AMR 0.01539 0.42723 2.89855
52 1A5Z OXM 0.0358 0.42692 2.89855
53 3GD9 GLC BGC BGC BGC 0.01015 0.42396 2.89855
54 4M4Q 21A 0.002164 0.41447 2.89855
55 1FNN ADP 0.008698 0.41275 2.89855
56 1A5Z FBP 0.006638 0.4097 2.89855
57 4MZU TYD 0.0384 0.40825 2.89855
58 2QCX PF1 0.04789 0.40587 2.89855
59 4LN7 1ZQ 0.01366 0.40413 2.89855
60 2BES RES 0.01936 0.40823 2.90698
61 2W58 ADP 0.0002979 0.52431 2.9703
62 1ULE GLA GAL NAG 0.01808 0.44273 3.33333
63 4BPM GSH 0.0005045 0.43256 3.37079
64 3NOJ PYR 0.002667 0.46299 3.38164
65 2JFV FLC 0.02179 0.42729 3.38164
66 2Y6P CTP 0.01027 0.42406 3.38164
67 4M7F BM3 0.01988 0.41974 3.38164
68 4KOA NDP 0.00832 0.41261 3.38164
69 3Q9L ATP 0.01824 0.41129 3.38164
70 2Z9V PXM 0.04335 0.40389 3.38164
71 3DGB MUC 0.02484 0.40359 3.38164
72 1UPT GTP 0.004168 0.42046 3.50877
73 2OFE NAG 0.0448 0.41168 3.52113
74 1BO4 COA 0.003239 0.45323 3.57143
75 2WJG GDP 0.0277 0.4058 3.7234
76 4K30 NLG 0.03769 0.40675 3.75
77 1V7R CIT 0.01371 0.4636 3.76344
78 1XKV ATP 0.0009307 0.47034 3.86473
79 2EB5 OXL 0.007577 0.44996 3.86473
80 1I4D GDP 0.008074 0.43759 3.86473
81 4B9E FAH 0.02213 0.43226 3.86473
82 1XP8 AGS 0.01267 0.42739 3.86473
83 4QOS ADP 0.007788 0.42568 3.86473
84 1FX8 BOG 0.004053 0.42489 3.86473
85 4PB2 5UD 0.004117 0.42096 3.86473
86 2NVK NAP 0.02086 0.41876 3.86473
87 4COQ SAN 0.03953 0.40572 3.86473
88 3BOS CDP 0.03067 0.40352 3.86473
89 3A1S GDP 0.02893 0.40127 3.86473
90 1NU4 MLA 0.01188 0.46717 4.12371
91 1QKQ MAN 0.00288 0.41061 4.22535
92 2OG2 MLI 0.0000006923 0.68935 4.34783
93 3B9Q MLI 0.000009431 0.61682 4.34783
94 2XT3 ADP 0.0006087 0.50691 4.34783
95 2VDF OCT 0.002293 0.47593 4.34783
96 1Y63 ADP 0.001371 0.47214 4.34783
97 1SQ5 ADP 0.001377 0.46693 4.34783
98 2OBM ADP 0.004155 0.46382 4.34783
99 3GJ0 GDP 0.004068 0.44821 4.34783
100 1VHT BA3 0.00287 0.44668 4.34783
101 3GJ4 GDP 0.004414 0.44641 4.34783
102 4LPS GDP 0.004958 0.4394 4.34783
103 3GJ5 GDP 0.0058 0.43602 4.34783
104 2YP9 SIA CMO 0.005707 0.42089 4.34783
105 3N5B ADP 0.0003717 0.41362 4.46429
106 2IMG MLT 0.02536 0.41356 4.63576
107 3Q85 GNP 0.004385 0.44656 4.73373
108 2ZTS ADP 0.01637 0.40022 4.78088
109 4AG5 ADP 0.0003384 0.52096 4.83092
110 3TKA CTN 0.03229 0.46154 4.83092
111 4IEE AGS 0.003787 0.45468 4.83092
112 1G7C 5GP 0.00412 0.44793 4.83092
113 2C04 GCP 0.004082 0.43136 4.83092
114 1G41 ADP 0.009023 0.42258 4.83092
115 1VCO GLN 0.0009197 0.42065 4.83092
116 1PEA ACM 0.04904 0.41957 4.83092
117 1QO0 BMD 0.04119 0.41351 4.83092
118 4Q3S X7A 0.001966 0.41282 4.83092
119 1I2B USQ 0.00162 0.40338 4.83092
120 1I2B NAD 0.00162 0.40338 4.83092
121 1I2B UPG 0.00162 0.40338 4.83092
122 3P7I P7I 0.04708 0.4022 4.83092
123 1Z6T ADP 0.01782 0.4016 4.83092
124 4IEN GDP 0.002029 0.40382 4.90798
125 1B0U ATP 0.002379 0.44631 4.96183
126 1F6B GDP 0.005675 0.43649 5.05051
127 2X7I CIT 0.009417 0.42971 5.19481
128 3K3G MMU 0.0003225 0.50596 5.31401
129 1T5C ADP 0.001145 0.49849 5.31401
130 3TK1 GDP 0.001059 0.48937 5.31401
131 3RC3 ANP 0.004169 0.45251 5.31401
132 2ZR9 DTP 0.00378 0.44983 5.31401
133 2Q8H TF4 0.02883 0.43813 5.31401
134 3ZPG 5GP 0.04612 0.42677 5.31401
135 3TBK ANP 0.01759 0.42428 5.31401
136 4HSE ADP 0.01187 0.42059 5.31401
137 3ESS 18N 0.02648 0.41539 5.31401
138 4HE2 AMP 0.0006482 0.41352 5.31401
139 2PL3 ADP 0.0236 0.41326 5.31401
140 1MZV AMP 0.02075 0.41067 5.31401
141 1TQ4 GDP 0.008667 0.40962 5.31401
142 4MOB ADP 0.04261 0.40476 5.31401
143 1YBH FAD 0.0004634 0.40396 5.31401
144 2F5X ASP 0.04768 0.4027 5.31401
145 1ZJ6 G3D 0.008015 0.42905 5.34759
146 3CH5 GDP 0.005071 0.43891 5.76923
147 3A1I UNU 0.0009458 0.46922 5.7971
148 2Q1A 2KT 0.006636 0.4528 5.7971
149 1I0Z OXM 0.02209 0.44453 5.7971
150 2JLR ANP 0.007406 0.42295 5.7971
151 1SKQ GDP 0.0159 0.42224 5.7971
152 1JWY ADP 0.01108 0.42208 5.7971
153 4DKX GDP 0.01449 0.42018 5.7971
154 2HFK E4H 0.02274 0.41702 5.7971
155 1HV9 UD1 0.0005154 0.41367 5.7971
156 1YRB GDP 0.01205 0.41291 5.7971
157 2WK1 SAH 0.00515 0.41057 5.7971
158 1R6B ADP 0.01889 0.41053 5.7971
159 4A4Z ANP 0.02373 0.40924 5.7971
160 3DKP ADP 0.02801 0.40555 5.7971
161 1WDT GTP 0.01303 0.40475 5.7971
162 3DEF GDP 0.01935 0.4031 5.7971
163 2XAU ADP 0.001432 0.4613 6.28019
164 1TV5 ORO 0.00186 0.44025 6.28019
165 2IS6 ADP 0.007638 0.43433 6.28019
166 3BER AMP 0.0116 0.42511 6.28019
167 4B47 GDP 0.01626 0.42173 6.28019
168 1G3Q ADP 0.0148 0.41581 6.28019
169 1V6A TRE 0.03935 0.41002 6.28019
170 1TV5 A26 0.006163 0.40467 6.28019
171 2QZ4 ADP 0.02408 0.40182 6.28019
172 1F5F DHT 0.007152 0.4152 6.34146
173 4F4S EFO 0.04399 0.40359 6.57895
174 1GXU 2HP 0.0003601 0.53923 6.59341
175 2AWN ADP 0.000008564 0.62269 6.76329
176 2IZ1 ATR 0.00188 0.47973 6.76329
177 4KFU ACP 0.003738 0.46305 6.76329
178 2IYL GDP 0.003587 0.45098 6.76329
179 1Y7P RIP 0.04497 0.4216 6.76329
180 1QZZ SAM 0.01072 0.41534 6.76329
181 1G7S GDP 0.02304 0.40622 6.76329
182 3O2K DST 0.03916 0.40597 6.76329
183 4P32 ADP 0.009162 0.4055 6.76329
184 1QDS PGA 0.03143 0.40272 6.76329
185 1JJV ATP 0.0008581 0.49693 6.79612
186 4BQS ADP 0.002881 0.45581 6.81818
187 4EXO PYR 0.0412 0.42364 6.84932
188 3W5J GDP 0.003358 0.46789 6.86275
189 3QDY A2G GAL 0.00669 0.46558 6.99301
190 4HI0 GDP 0.003635 0.42643 7.03518
191 1JI0 ATP 0.0003533 0.51474 7.24638
192 2CBZ ATP 0.0005233 0.51148 7.24638
193 1YQT ADP 0.000679 0.50255 7.24638
194 1OXV ANP 0.0005951 0.49639 7.24638
195 1GJW GLC 0.01021 0.44946 7.24638
196 3I0O SMI 0.006872 0.44638 7.24638
197 3JQ3 ADP 0.008299 0.4281 7.24638
198 1KK1 GNP 0.02546 0.41153 7.24638
199 3RK0 AMP 0.01784 0.40975 7.24638
200 2CJW GDP 0.004732 0.44488 7.29167
201 4QM7 GTP 0.00005758 0.54182 7.60234
202 3GJ8 GDP 0.005122 0.43869 7.6087
203 4Q3F TLA 0.04132 0.40956 7.69231
204 1G6H ADP 0.0002096 0.53376 7.72947
205 1JJ7 ADP 0.0002256 0.53148 7.72947
206 2GK6 ADP 0.001195 0.48658 7.72947
207 2ZO9 MLI 0.0008305 0.46895 7.72947
208 2RCN GDP 0.00294 0.45536 7.72947
209 1FWY UD1 0.0002355 0.42371 7.72947
210 3QV9 QV7 0.04395 0.40769 7.72947
211 2ZSC BTN 0.01315 0.41166 7.80142
212 1R4A GNP 0.008697 0.40075 7.84314
213 1WKL ADP 0.009659 0.40675 8.0292
214 3NHB ADP 0.0004287 0.5142 8.21256
215 2VF7 ADP 0.002863 0.45121 8.21256
216 4TO8 FLC 0.01361 0.43024 8.21256
217 4KBF AMP 0.01182 0.42896 8.21256
218 2QV7 ADP 0.006996 0.4192 8.21256
219 1B5E DCM 0.01728 0.41822 8.21256
220 4KCT FDP 0.01764 0.40995 8.21256
221 4LJ9 ACP 0.03022 0.40385 8.21256
222 1U0J ADP 0.007605 0.43894 8.69565
223 2QF7 COA 0.008205 0.42016 8.69565
224 1UJ2 ADP 0.003788 0.41011 8.69565
225 4DCT GDP 0.02079 0.40846 8.69565
226 2NZ2 ASP 0.01393 0.42692 8.71671
227 2NZ2 CIR 0.003174 0.40305 8.71671
228 1WS4 GYP 0.0173 0.4168 9.02256
229 1S8F GDP 0.0035 0.44252 9.03955
230 4RJK PYR 0.02074 0.43956 9.17874
231 1W7J ADP BEF 0.006667 0.42147 9.17874
232 1J2Z SOG 0.009788 0.41155 9.17874
233 1Z0F GDP 0.007645 0.43007 9.49721
234 1O51 ADP 0.001744 0.41456 9.64912
235 1G6O ADP 0.01242 0.41584 9.66184
236 2GDJ ANP 0.0192 0.41395 9.66184
237 2A5J GDP 0.008507 0.42382 9.94764
238 2D2F ADP 0.0003316 0.50936 10.1449
239 2NCD ADP 0.0009568 0.4943 10.1449
240 3B7G ANP 0.02067 0.40858 10.1449
241 3CV2 OXL 0.04257 0.4037 10.1449
242 3EZ2 ADP 0.04054 0.40088 10.1449
243 1QD0 RR6 0.02803 0.40134 10.1562
244 2IYG FMN 0.004361 0.43578 10.4839
245 1XX4 BAM 0.0005817 0.49396 10.628
246 3W8S GSH 0.02903 0.41641 10.6796
247 1YRX FMN 0.01005 0.41285 10.7438
248 2QN6 GDP 0.0126 0.42751 10.7527
249 1Z0A GDP 0.008459 0.42394 10.9195
250 3VOZ 04A 0.0003615 0.46607 11.1111
251 4NON GDP 0.008125 0.43297 11.1111
252 1XMV ADP 0.01361 0.41762 11.1111
253 3ZIA ATP 0.01594 0.41421 11.1111
254 3PQC GDP 0.01739 0.40873 11.2821
255 1NVU GTP 0.00009982 0.40083 12.0482
256 1DAR GDP 0.001068 0.47763 12.0773
257 3GJ7 GDP 0.003718 0.45019 12.2449
258 1BTN I3P 0.0001835 0.59602 12.2642
259 1S9D GDP 0.005877 0.43573 12.3153
260 3MD0 GDP 0.0006004 0.49619 12.5604
261 2EFE GNH 0.007096 0.42383 12.5604
262 1E4E PHY 0.02044 0.40037 13.0435
263 4DID GDP 0.01326 0.4182 13.4715
264 2WIC GNP 0.01736 0.41236 13.5266
265 2CUN 3PG 0.04193 0.40127 13.5266
266 1A4R GNH 0.01745 0.40202 13.6126
267 2NGR GDP 0.02911 0.40114 13.6126
268 2WMO GTP 0.01593 0.41059 13.6842
269 2V7Q ATP 0.01127 0.41788 14.0097
270 1KK8 BEF ADP 0.01121 0.41097 14.0097
271 1B7T ADP 0.02562 0.40051 14.0097
272 2Q37 3AL 0.04428 0.40753 14.3646
273 2VOH CIT 0.04383 0.42472 14.6497
274 2J59 GTP 0.01019 0.40348 14.881
275 2WHX ADP 0.000909 0.49645 14.9758
276 2DPY ADP 0.005511 0.45123 14.9758
277 3E70 GDP 0.001801 0.46116 15.4589
278 2FH5 GTP 0.01091 0.4016 15.4589
279 4CVN ADP 0.0009862 0.49102 16.2304
280 3IIJ ADP 0.0008008 0.48396 18.3333
281 4LC1 GDP 0.003493 0.45157 18.8406
282 4DN8 BMA 0.001181 0.48966 19.2308
283 1SVI GDP 0.008695 0.43591 19.4872
284 3UIE ANP 0.001186 0.46526 25
285 1JXM 5GP 0.000003433 0.63395 33.8164
286 3A4M ADP 0.0003936 0.51224 33.8164
Pocket No.: 2; Query (leader) PDB : 2F3R; Ligand: G5P; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2f3r.bio1) has 33 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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