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Receptor
PDB id Resolution Class Description Source Keywords
2EJT 2.2 Å EC: 2.1.1.32 COMPLEX STRUCTURE OF TRM1 FROM PYROCOCCUS HORIKOSHII WITH S- L-METHIONINE PYROCOCCUS HORIKOSHII TRNA MODIFICATION ENZYME GUANINE-26N(2)-N(2)-DIMETHYLTRANSSTRUCTURAL GENOMICS NPPSFA NATIONAL PROJECT ON PROTEIN STAND FUNCTIONAL ANALYSES RIKEN STRUCTURAL GENOMICS/PROTEOMIINITIATIVE RSGI TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF TRNA N(2),N(2)-GUANOSINE DIMETHYLTRANSFERASE TRM1 FROM PYROCOCCUS HORIKOSHII J.MOL.BIOL. V. 383 871 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:601;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
SAM A:501;
Valid;
none;
submit data
398.437 C15 H22 N6 O5 S C[S@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2EJU 1.95 Å EC: 2.1.1.32 COMPLEX STRUCTURE OF TRM1 FROM PYROCOCCUS HORIKOSHII WITH S- L-HOMOCYSTEIN PYROCOCCUS HORIKOSHII TRNA MODIFICATION ENZYME GUANINE-26N(2)-N(2)-DIMETHYLTRANSSTRUCTURAL GENOMICS NPPSFA NATIONAL PROJECT ON PROTEIN STAND FUNCTIONAL ANALYSES RIKEN STRUCTURAL GENOMICS/PROTEOMIINITIATIVE RSGI TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF TRNA N(2),N(2)-GUANOSINE DIMETHYLTRANSFERASE TRM1 FROM PYROCOCCUS HORIKOSHII J.MOL.BIOL. V. 383 871 2008
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2EJU - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 2EJT - SAM C15 H22 N6 O5 S C[S@@+](CC....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2EJU - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 2EJT - SAM C15 H22 N6 O5 S C[S@@+](CC....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2EJU - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 2EJT - SAM C15 H22 N6 O5 S C[S@@+](CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAM; Similar ligands found: 202
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 ADN 0.565789 0.773333
9 RAB 0.565789 0.773333
10 XYA 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 5AL 0.510417 0.743902
25 54H 0.510204 0.673913
26 VMS 0.510204 0.673913
27 0UM 0.51 0.857143
28 AMP 0.505747 0.707317
29 LMS 0.505747 0.666667
30 A 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 SON 0.5 0.746988
34 SSA 0.5 0.684783
35 6RE 0.5 0.78481
36 K15 0.5 0.883117
37 5AD 0.5 0.75
38 SRP 0.5 0.746988
39 LSS 0.49505 0.706522
40 CA0 0.494624 0.714286
41 A12 0.494505 0.705882
42 AP2 0.494505 0.705882
43 ME8 0.490385 0.841463
44 TSB 0.49 0.681319
45 53H 0.49 0.666667
46 DAL AMP 0.49 0.765432
47 5CA 0.49 0.684783
48 ACP 0.489362 0.694118
49 ADP 0.48913 0.690476
50 5AS 0.48913 0.648936
51 J7C 0.488889 0.772152
52 A2D 0.488889 0.690476
53 ZAS 0.488636 0.769231
54 9ZD 0.485149 0.729412
55 9ZA 0.485149 0.729412
56 8QN 0.485149 0.743902
57 GAP 0.484536 0.73494
58 AN2 0.483871 0.682353
59 A3S 0.483871 0.813333
60 A7D 0.483871 0.851351
61 GJV 0.483516 0.775
62 SRA 0.483146 0.694118
63 LAD 0.480769 0.752941
64 KAA 0.480769 0.698925
65 GSU 0.480769 0.722222
66 AMO 0.480392 0.746988
67 DSZ 0.480392 0.703297
68 52H 0.48 0.666667
69 M33 0.478723 0.722892
70 BA3 0.478261 0.690476
71 MAO 0.478261 0.82716
72 NEC 0.477778 0.75
73 AOC 0.477778 0.776316
74 DSH 0.477778 0.842105
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 NVA LMS 0.475728 0.736264
78 Y3J 0.47561 0.706667
79 G5A 0.474227 0.684783
80 A3T 0.473684 0.8
81 B4P 0.473118 0.690476
82 AP5 0.473118 0.690476
83 A3N 0.472527 0.766234
84 KB1 0.471698 0.833333
85 PRX 0.46875 0.73494
86 APC 0.46875 0.705882
87 AT4 0.468085 0.686047
88 PAJ 0.466019 0.712644
89 4AD 0.466019 0.759036
90 RBY 0.463918 0.72619
91 ADP PO3 0.463918 0.728395
92 ADV 0.463918 0.72619
93 ADX 0.463158 0.666667
94 MHZ 0.463158 0.82716
95 AU1 0.463158 0.674419
96 YAP 0.462963 0.738095
97 TXA 0.462264 0.72619
98 NB8 0.462264 0.72093
99 A3G 0.461538 0.802632
100 VRT 0.459184 0.842105
101 XAH 0.458716 0.715909
102 YSA 0.458716 0.684783
103 HEJ 0.458333 0.690476
104 50T 0.458333 0.682353
105 ATP 0.458333 0.690476
106 LEU LMS 0.457143 0.717391
107 7D7 0.45679 0.723684
108 KH3 0.455357 0.871795
109 ACQ 0.454545 0.694118
110 AR6 0.453608 0.710843
111 APR 0.453608 0.710843
112 AQP 0.453608 0.690476
113 5FA 0.453608 0.690476
114 NSS 0.451923 0.703297
115 FA5 0.449541 0.746988
116 A5D 0.44898 0.789474
117 AD9 0.44898 0.674419
118 AGS 0.44898 0.678161
119 SAP 0.44898 0.678161
120 PTJ 0.448598 0.72093
121 YLB 0.448276 0.758621
122 YLP 0.447368 0.738636
123 8X1 0.446602 0.680851
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 3AM 0.444444 0.674699
128 MYR AMP 0.444444 0.776471
129 OAD 0.443396 0.73494
130 2VA 0.443299 0.779221
131 S8M 0.442308 0.831169
132 OOB 0.442308 0.722892
133 TYR AMP 0.441441 0.759036
134 6YZ 0.441176 0.694118
135 ADP VO4 0.441176 0.702381
136 VO4 ADP 0.441176 0.702381
137 T99 0.44 0.686047
138 TAT 0.44 0.686047
139 ANP 0.44 0.674419
140 WAQ 0.439252 0.75
141 B5Y 0.436364 0.717647
142 8PZ 0.436364 0.684783
143 F0P 0.435897 0.844156
144 YLC 0.435897 0.755814
145 AAT 0.435644 0.797468
146 1ZZ 0.435185 0.755814
147 9K8 0.435185 0.663158
148 3OD 0.435185 0.73494
149 NVA 2AD 0.434343 0.855263
150 00A 0.433962 0.689655
151 DLL 0.433962 0.722892
152 ARG AMP 0.433628 0.727273
153 7MD 0.433628 0.715909
154 ATF 0.431373 0.666667
155 SO8 0.43 0.792208
156 3UK 0.429907 0.714286
157 A6D 0.429907 0.72619
158 9X8 0.429907 0.717647
159 F2R 0.429752 0.7
160 5SV 0.428571 0.741176
161 AMP DBH 0.428571 0.714286
162 TYM 0.42735 0.746988
163 WSA 0.42735 0.692308
164 9SN 0.427273 0.681818
165 AHZ 0.426087 0.755814
166 P5A 0.425926 0.691489
167 B5V 0.425926 0.705882
168 PR8 0.425926 0.744186
169 A A 0.425926 0.710843
170 3NZ 0.425926 0.807692
171 A1R 0.424528 0.709302
172 2A5 0.424242 0.674419
173 7MC 0.423729 0.719101
174 B5M 0.423423 0.717647
175 7D5 0.422222 0.658824
176 JB6 0.422018 0.709302
177 FYA 0.422018 0.722892
178 AYB 0.421488 0.75
179 A22 0.419048 0.682353
180 MAP 0.419048 0.659091
181 2AM 0.417582 0.666667
182 TAD 0.417391 0.712644
183 A3P 0.416667 0.686747
184 ADP BMA 0.416667 0.714286
185 25A 0.415094 0.690476
186 YLA 0.413223 0.719101
187 8Q2 0.411765 0.663158
188 A3R 0.411215 0.709302
189 ADQ 0.411215 0.694118
190 48N 0.410256 0.72093
191 0XU 0.41 0.824324
192 GA7 0.408696 0.72619
193 7D3 0.40625 0.643678
194 PAP 0.405941 0.678571
195 DQV 0.405172 0.702381
196 OVE 0.404255 0.662791
197 4UV 0.403509 0.697674
198 AF3 ADP 3PG 0.403361 0.712644
199 3AD 0.402299 0.783784
200 CMP 0.402062 0.691358
201 2BA 0.402062 0.682927
202 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2EJU; Ligand: SAH; Similar sites found with APoc: 830
This union binding pocket(no: 1) in the query (biounit: 2eju.bio2) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 2BOS GLA GAL GLC None
2 2BOS GLA GAL GLC NBU None
3 1MV8 NAD 1.0582
4 4ITU 1HS 1.11524
5 4ITU NAI 1.11524
6 2GDZ NAD 1.1236
7 2GV8 FAD 1.32275
8 2GVC FAD 1.32275
9 1VQW FAD 1.32275
10 2IID FAD 1.32275
11 2IID PHE 1.32275
12 2C5A NAD 1.32275
13 2C5A GDC 1.32275
14 4UP4 GAL NAG 1.32275
15 5F8F SFG 1.32626
16 2VHW NAI 1.32626
17 1XHL NDP 1.3468
18 4YAG NAI 1.38408
19 4USQ FAD 1.38504
20 3ZNN 4WL 1.44092
21 3ZNN FAD 1.44092
22 5E72 SAM 1.44509
23 1HDG NAD 1.50602
24 5K0A FAD 1.51515
25 3M6W SAM 1.5873
26 2NPX FAD 1.5873
27 2NPX NAD 1.5873
28 2Z3Y F2N 1.5873
29 5THZ SAH 1.5873
30 6FP4 E1T 1.5873
31 6FP4 FAD 1.5873
32 2ZUX RAM 1.5873
33 4EDF UPG 1.5873
34 5YB7 FAD 1.5873
35 5YB7 ORN 1.5873
36 3ABI NAD 1.64384
37 5JE8 NAD 1.65563
38 1N2X SAM 1.66113
39 5THY SAH 1.7284
40 3GU3 SAH 1.76056
41 1XKQ NDP 1.78571
42 3I53 SAH 1.80723
43 6GAS FAD 1.81269
44 1SOW NAD 1.82927
45 3FPZ AHZ 1.84049
46 3NDJ SAH 1.85185
47 3NDJ JHZ 1.85185
48 3ICT FAD 1.85185
49 3QVP FAD 1.85185
50 3ICS FAD 1.85185
51 3ICR FAD 1.85185
52 4OPC PGT 1.85185
53 4OPC FDA 1.85185
54 5Y77 FAD 1.85185
55 3ICT ADP 1.85185
56 3ICS ADP 1.85185
57 2JB2 FAD 1.85185
58 2JB2 PHE 1.85185
59 5EB4 FAD 1.85185
60 6EL3 NAP 1.85185
61 5UAV NDP 1.86335
62 5UAV TFB 1.86335
63 5DLY 5D7 1.8797
64 5DLY SAH 1.8797
65 2A14 SAH 1.90114
66 4Y9D NAI 1.96721
67 5N6C NAD 2
68 6B92 SAH 2.04082
69 3V1Y NAD 2.07715
70 3CMC NAD 2.09581
71 4PLT OXM 2.1148
72 4PLT NAI 2.1148
73 3X0D SAH 2.1164
74 4KGD FAD 2.1164
75 4KGD TDP 2.1164
76 3CGD FAD 2.1164
77 3CGD COA 2.1164
78 2YVF FAD 2.1164
79 4D5G FAD 2.1164
80 4D5G TPP 2.1164
81 1H82 FAD 2.1164
82 1H82 GZZ 2.1164
83 2R4J 13P 2.1164
84 2R4J FAD 2.1164
85 3CGB FAD 2.1164
86 2XVE FAD 2.1164
87 2XVF FAD 2.1164
88 3NKS FAD 2.1164
89 6AIN FAD 2.1164
90 3CGD NAD 2.1164
91 4MIG G3F 2.1164
92 3OZ2 FAD 2.1164
93 2GMH FAD 2.1164
94 6FHO FAD 2.1164
95 2E5V FAD 2.1164
96 1E5Q NDP 2.1164
97 2YVF NAD 2.1164
98 5JWC FAD 2.1164
99 1PJS NAD 2.1164
100 1XCL SAH 2.12766
101 4DCM SAM 2.13333
102 3LCV SAM 2.13523
103 1FP1 SAH 2.15054
104 5XNC MTA 2.15633
105 3P9C SAH 2.1978
106 1DL5 SAH 2.2082
107 5ULP KB1 2.23881
108 2YY7 NAD 2.24359
109 2DTX BMA 2.27273
110 5ICE 2H4 2.27273
111 5GT9 NAP 2.28137
112 1ZEM NAD 2.29008
113 3DXY SAM 2.29358
114 3LST SAH 2.29885
115 1R37 NAD 2.30548
116 3H9E NAD 2.31214
117 6CI9 NAP 2.3166
118 4JNA FAD 2.35294
119 2DT5 NAD 2.36967
120 3GRU AMP 2.37288
121 3QOX SAH 2.38095
122 4KRG SAH 2.38095
123 5ERG SAM 2.38095
124 1X87 NAD 2.38095
125 5WKC FAD 2.38095
126 1T9D P25 2.38095
127 2DKH 3HB 2.38095
128 2DKH FAD 2.38095
129 1Q9I TEO 2.38095
130 1Q9I FAD 2.38095
131 1T9D PYD 2.38095
132 1T9D 1MM 2.38095
133 1T9D FAD 2.38095
134 4AP3 FAD 2.38095
135 4AP3 NAP 2.38095
136 3X0V FAD 2.38095
137 2NVK FAD 2.38095
138 5KOX FAD 2.38095
139 5KOX RFP 2.38095
140 4HA6 FAD 2.38095
141 3UOY NAP 2.38095
142 3UOY FAD 2.38095
143 4YKG FAD 2.38095
144 3T31 FAD 2.38095
145 3T31 DCQ 2.38095
146 5I39 FAD 2.38095
147 3NYC FAD 2.38095
148 3NYC IAR 2.38095
149 3KL3 GCU 2.38095
150 1FUR MLT 2.38095
151 6GFK SAH 2.39044
152 4JCA CIT 2.39521
153 3U31 NAD 2.41379
154 5JE0 AZ8 2.42915
155 5JE0 SAH 2.42915
156 4LWP SAH 2.44565
157 1ZQ9 SAM 2.45614
158 1QAN SAH 2.45902
159 1NV8 SAM 2.46479
160 1NV8 MEQ 2.46479
161 1KYZ SAH 2.46575
162 1KYZ FER 2.46575
163 3U4C NDP 2.4911
164 6ECT SAM 2.49221
165 2HQM FAD 2.50522
166 3CIF NAD 2.50696
167 3CIF G3H 2.50696
168 1NW5 SAM 2.50784
169 1P1C SAH 2.51256
170 5LD5 NAD 2.51397
171 3EVG SAH 2.54545
172 5O42 NAD 2.55474
173 5O42 9JW 2.55474
174 5O42 BGC 2.55474
175 3CBG SAH 2.58621
176 2PX8 SAH 2.60223
177 3DMH SAM 2.6455
178 3DMH GMP 2.6455
179 3L9W GSH 2.6455
180 3L9W AMP 2.6455
181 3BGD SAH 2.6455
182 3SQP FAD 2.6455
183 6D6Y SAH 2.6455
184 1V59 FAD 2.6455
185 4JDR FAD 2.6455
186 4YRY NAD 2.6455
187 3LAD FAD 2.6455
188 1ZK7 FAD 2.6455
189 5BRT CH9 2.6455
190 5BRT FAD 2.6455
191 4YRY FAD 2.6455
192 1V59 NAD 2.6455
193 4FWE FAD 2.6455
194 3NUG NAD 2.6455
195 5U8U FAD 2.6455
196 4N49 SAM 2.6455
197 3BGD PM6 2.6455
198 3LXD FAD 2.6455
199 1RYI GOA 2.6455
200 5LTJ ADP 2.6455
201 5M67 NAD 2.6455
202 1RYI FAD 2.6455
203 5M67 ADE 2.6455
204 5M67 3D1 2.6455
205 5EOW FAD 2.6455
206 2Q1S NAI 2.65252
207 5K7U SAM 2.66667
208 1XDS SAM 2.6738
209 1QZZ SAM 2.6738
210 5OJI ISN 2.69231
211 5OJI NAP 2.69231
212 5MW4 5JU 2.69461
213 3OU2 SAH 2.75229
214 2Q7V FAD 2.76923
215 3WMX NAD 2.7933
216 5J60 FAD 2.8125
217 5IL1 SAM 2.83019
218 3A4V NAD 2.83912
219 3A4V PYR 2.83912
220 3ZV6 NAD 2.84698
221 3ZV6 4HB 2.84698
222 6GKV SAH 2.849
223 5N0J FAD 2.849
224 5W7M SAH 2.88462
225 1NVM NAD 2.89855
226 3VPH OXM 2.90323
227 3VPH NAD 2.90323
228 4KRI SAH 2.91005
229 5DNK SAH 2.91005
230 5JJR SAH 2.91005
231 5MPT SAH 2.91005
232 3KLJ FAD 2.91005
233 1V5F TPP 2.91005
234 1V5F FAD 2.91005
235 1GET FAD 2.91005
236 4REP FAD 2.91005
237 4IV9 FAD 2.91005
238 1GET NAP 2.91005
239 1LVL NAD 2.91005
240 3UCL NAP 2.91005
241 3UCL CYH 2.91005
242 3UCL FAD 2.91005
243 3GMB FAD 2.91005
244 4BJZ P3A 2.91005
245 4BJZ FAD 2.91005
246 2Y6Q FAD 2.91005
247 2Y6Q I7T 2.91005
248 5W7R SAH 2.91005
249 5HXI FAD 2.91005
250 5X68 FAD 2.91005
251 1LVL FAD 2.91005
252 3OJO NAD 2.91005
253 5FJN BE2 2.91005
254 5FJN FAD 2.91005
255 5HXI 5HN 2.91005
256 3NJ4 NAD 2.91005
257 4OM8 NAD 2.91262
258 1G55 SAH 2.91545
259 3QJ4 FAD 2.92398
260 3BXO SAM 2.92887
261 6F9Q NAD 2.94118
262 4RF2 NAP 2.94118
263 3TLJ SAH 2.94906
264 4Y4V DAL 2.94985
265 2P41 SAH 2.95082
266 5MGZ SAH 2.9661
267 3T7S SAM 2.98507
268 3LZW NAP 3.01205
269 3LZW FAD 3.01205
270 1J0X NAD 3.01205
271 2XVM SAH 3.01508
272 2BZG SAH 3.01724
273 4NEC SAH 3.0303
274 2GJN NIS 3.04878
275 2GJN FMN 3.04878
276 5Y8L NAD 3.05085
277 5Y8L HUI 3.05085
278 3AB1 FAD 3.05556
279 1ZBQ NAD 3.0581
280 5N53 8NB 3.07692
281 1BW9 NAD 3.08989
282 4RDH AMP 3.125
283 4RDI ATP 3.125
284 1GZ6 NAI 3.1348
285 3FRH SAH 3.16206
286 1SQF SAM 3.1746
287 4AZW SAM 3.1746
288 4TXI FAD 3.1746
289 1NAA ABL 3.1746
290 1NAA 6FA 3.1746
291 4MOP 2H5 3.1746
292 2BRY FAD 3.1746
293 5TUF TDC 3.1746
294 3NTA FAD 3.1746
295 3NT6 FAD 3.1746
296 3NTD FAD 3.1746
297 4Z24 FAD 3.1746
298 6B3A SAM 3.1746
299 5TUF FAD 3.1746
300 4U8P UDP 3.1746
301 4U8P FDA 3.1746
302 3FG2 FAD 3.1746
303 6F7L FAD 3.1746
304 5F2K OCA 3.1746
305 5F2K SAH 3.1746
306 5XLX SAH 3.19149
307 5TWB FAD 3.19767
308 2YYY NAP 3.207
309 2EWM NAD 3.21285
310 1XG5 NAP 3.22581
311 2BGM NAJ 3.23741
312 3OFK SAH 3.24074
313 3MAG SAH 3.25733
314 4D79 ATP 3.26087
315 1IM8 SAI 3.27869
316 2XYQ SAH 3.27869
317 1EDO NAP 3.27869
318 4X7Y SAH 3.28467
319 2O07 SPD 3.28947
320 2O07 MTA 3.28947
321 6FDF SAH 3.29341
322 4Z0H NAD 3.29341
323 6BQ6 TER 3.32326
324 3MCT SAH 3.367
325 1JG3 ADN 3.40426
326 1FP2 SAH 3.40909
327 1FP2 HMO 3.40909
328 3H8V ATP 3.42466
329 6C8R EQV 3.43915
330 6C8R SAH 3.43915
331 2CDU FAD 3.43915
332 4EMI FAD 3.43915
333 4EMI NAD 3.43915
334 5VN0 FAD 3.43915
335 5VN0 NAI 3.43915
336 5G3U FDA 3.43915
337 4X9M FAD 3.43915
338 4RPL 3UC 3.43915
339 4RPL FAD 3.43915
340 4C3Y FAD 3.43915
341 2C7G ODP 3.43915
342 2C7G FAD 3.43915
343 3AYI HCI 3.43915
344 3AYI FAD 3.43915
345 5ZYN FAD 3.43915
346 4C3Y ANB 3.43915
347 5G3U ITW 3.43915
348 5GWT SIN 3.43915
349 4YSX FAD 3.43915
350 5GWT NAD 3.43915
351 2CDU ADP 3.43915
352 2IXB NAD 3.43915
353 2IXB A2G 3.43915
354 1NM5 NAD 3.44828
355 1NM5 NAP 3.44828
356 2CUL FAD 3.44828
357 2FK8 SAM 3.45912
358 4BLW AMP 3.46021
359 4BLW SAH 3.46021
360 5JGL SAM 3.46021
361 1Y8Q ATP 3.46821
362 4R6W SAH 3.48837
363 4R6W PC 3.48837
364 4NTD FAD 3.52941
365 1G0N NDP 3.53357
366 1G0N PHH 3.53357
367 2Q0L FAD 3.53698
368 2Q0L NAP 3.53698
369 1I9G SAM 3.57143
370 5AHO TLA 3.57143
371 5BSZ SAH 3.6
372 1H2B NAJ 3.62117
373 4KIB SAH 3.64146
374 1YC5 NCA 3.65854
375 3WV8 ATP 3.66972
376 4A6D SAM 3.68272
377 2BD0 NAP 3.68852
378 4DMG SAM 3.7037
379 5GM1 SAH 3.7037
380 3C6K SPD 3.7037
381 3C6K MTA 3.7037
382 1E1M FAD 3.7037
383 1E1M NAP 3.7037
384 6DEN G8A 3.7037
385 6DEN FAD 3.7037
386 6DEN TP9 3.7037
387 4M52 FAD 3.7037
388 2C31 TZD 3.7037
389 2C31 ADP 3.7037
390 2RGJ FAD 3.7037
391 4M52 M52 3.7037
392 2A8X FAD 3.7037
393 5A9A UTP 3.7037
394 5F7U GLC GLC 3.7037
395 5DM1 SAH 3.74532
396 5DM1 5D7 3.74532
397 4M37 SAH 3.79009
398 4M38 SAH 3.79009
399 3GGO ENO 3.82166
400 3GGO NAI 3.82166
401 1RJW ETF 3.83481
402 3VC1 GST 3.84615
403 3VC1 SAH 3.84615
404 4M73 SAH 3.85757
405 4M73 M72 3.85757
406 4J4H 1J1 3.861
407 4J4H NAI 3.861
408 1NJR XYL 3.87324
409 1PNO NAP 3.88889
410 1XTP SAI 3.93701
411 2HJR APR 3.96341
412 4C4A SAH 3.96825
413 3A25 SAM 3.96825
414 1D4D FAD 3.96825
415 1PS9 FAD 3.96825
416 5HSA FAS 3.96825
417 2VVL FAD 3.96825
418 2VVM FAD 3.96825
419 4D04 FAD 3.96825
420 4D04 NAP 3.96825
421 5GSN NAP 3.96825
422 5GSN FAD 3.96825
423 5GSN MMZ 3.96825
424 3OND NAD 3.96825
425 3OND ADN 3.96825
426 5Z75 NAD 3.96825
427 4NBU NAI 4
428 6GAR FAD 4.01146
429 2OOR TXP 4.02299
430 4PIO AVI 4.02477
431 4PIO SAH 4.02477
432 2PT9 2MH 4.04984
433 2PT9 S4M 4.04984
434 5YU3 PRO 4.06977
435 5YU3 NAD 4.06977
436 3CTY FAD 4.07523
437 1PR9 NAP 4.09836
438 3D3W NAP 4.09836
439 5U19 SAH 4.10557
440 5U19 827 4.10557
441 3RFV 15L 4.11985
442 3RFV NAI 4.11985
443 5FEU NAP 4.12371
444 1H5Q NAP 4.15094
445 2A9W GA9 4.16667
446 2UYQ SAM 4.19355
447 1DLJ NAI 4.22886
448 4B63 NAP 4.2328
449 4B63 ORN 4.2328
450 4B63 FAD 4.2328
451 1GPE FAD 4.2328
452 2RAB NAD 4.2328
453 2RAB FAD 4.2328
454 1PN0 IPH 4.2328
455 1PN0 FAD 4.2328
456 5BUK FAD 4.2328
457 5L2M 6ZY 4.2328
458 2G5C NAD 4.27046
459 4X60 SFG 4.28571
460 4X60 3XV 4.28571
461 3G2O SAM 4.34783
462 5FA5 MTA 4.35967
463 4GQB 0XU 4.36047
464 5BJX NAD 4.37158
465 5BJX UDP 4.37158
466 5O4J SAH 4.37956
467 5O4J 9KH 4.37956
468 1AE1 NAP 4.3956
469 5YF1 SFG 4.41989
470 5YF1 8V0 4.41989
471 1EJ0 SAM 4.44444
472 3QWI NAP 4.44444
473 3QWI CUE 4.44444
474 5X62 SAH 4.49735
475 3SSO SAH 4.49735
476 2WPF WPF 4.49735
477 2WPF FAD 4.49735
478 1MO9 FAD 4.49735
479 1MO9 KPC 4.49735
480 1QO8 FAD 4.49735
481 1Q1R FAD 4.49735
482 4CNK FAD 4.49735
483 5NA1 FAD 4.49735
484 2ZWA SAH 4.49735
485 1WG8 SAM 4.5614
486 3PFG SAM 4.56274
487 3PFG TLO 4.56274
488 3GDH SAH 4.56432
489 4XUC SAM 4.58716
490 4XUC 43G 4.58716
491 2I7C AAT 4.59364
492 2HNK SAH 4.60251
493 3JWH SAH 4.60829
494 6AA8 NAD 4.63576
495 4TQG NDP 4.64396
496 2VT3 ATP 4.65116
497 4JJF FE9 4.65116
498 4JJF N2I 4.65116
499 2PK3 A2R 4.6729
500 5KVA SAM 4.67626
501 3EVF GTA 4.69314
502 3EVF SAH 4.69314
503 3A4T SFG 4.74453
504 5KOK SAH 4.7619
505 2GAG NAD 4.7619
506 5KOK S9T 4.7619
507 5KOK R9T 4.7619
508 6ER9 FAD 4.7619
509 6ER9 NAP 4.7619
510 5TTJ FAD 4.7619
511 1OBB NAD 4.7619
512 3K7M FAD 4.7619
513 1VKO NAD 4.7619
514 5GZZ GSH 4.7619
515 3VSE SAH 4.77387
516 1BC5 SAH 4.83271
517 5T2U NAP 4.83871
518 5BW4 SAM 4.86891
519 6DUB SAH 4.95496
520 3FZG SAM 5
521 4TM3 FAD 5.02645
522 2IVD FAD 5.02645
523 5XWV 8H6 5.02645
524 5XWV NDP 5.02645
525 3GWZ SAH 5.02645
526 2WET FAD 5.02645
527 3GXO SAH 5.02645
528 2JHP SAH 5.02645
529 3MQ2 SAH 5.04587
530 4PLG OXM 5.08982
531 4PLG NAI 5.08982
532 6EQS BV8 5.09091
533 2ZFU SAH 5.11628
534 2PXX SAH 5.11628
535 2NXE SAM 5.11811
536 3RIY NAD 5.12821
537 2PHX MAN MAN 5.15873
538 1Q8S MAN MMA 5.15873
539 1IY8 NAD 5.24345
540 1T26 NAI 5.2795
541 1T26 GBD 5.2795
542 1OMO NAD 5.2795
543 2DPM SAM 5.28169
544 1COY FAD 5.29101
545 4XQC 13D 5.29101
546 4XQC NAD 5.29101
547 1COY AND 5.29101
548 5WGR FAD 5.29101
549 4D7E FAD 5.29101
550 5M90 JIF 5.29101
551 1GTE FAD 5.29101
552 2A92 NAI 5.29595
553 3GCZ SAM 5.31915
554 3EGI ADP 5.33981
555 5YJ1 6EL 5.40541
556 5YIZ EF2 5.40541
557 5YJ0 EF2 5.40541
558 3OID NDP 5.42636
559 3HVJ 705 5.42986
560 4MO2 FDA 5.43478
561 4MO2 FAD 5.43478
562 1I8T FAD 5.44959
563 3MB5 SAM 5.4902
564 2B4R NAD 5.50725
565 2B4R AES 5.50725
566 4FN4 NAD 5.51181
567 3FUU ADN 5.53506
568 5WP4 SAH 5.55556
569 1BZL GCG 5.55556
570 1BZL FAD 5.55556
571 5JCM ISD 5.55556
572 5JCM FAD 5.55556
573 5JCM NAD 5.55556
574 3AXB FAD 5.55556
575 3AXB PRO 5.55556
576 4YNU FAD 5.55556
577 4YNU LGC 5.55556
578 5BVA FAD 5.55556
579 2FR1 NDP 5.55556
580 4FZV SAM 5.57103
581 1VL8 NAP 5.61798
582 1SB8 NAD 5.68182
583 1LSS NAD 5.71429
584 1L3I SAH 5.72917
585 1E3W NAD 5.74713
586 1U7T TDT 5.74713
587 1E6W NAD 5.76923
588 2V6G NAP 5.76923
589 5E1M SAH 5.80913
590 5E1M PRO PRO LYS ARG ILE ALA 5.80913
591 3S1S SAH 5.82011
592 1ELI PYC 5.82011
593 4J36 1HR 5.82011
594 4J36 FAD 5.82011
595 2RGO FAD 5.82011
596 4DSG UDP 5.82011
597 4DSG FAD 5.82011
598 5FTW SAH 5.85938
599 1LTH NAD 5.95611
600 3G89 SAM 6.0241
601 1YBH FAD 6.08466
602 5J5Z FAD 6.08466
603 4BV6 FAD 6.08466
604 3IHG FAD 6.08466
605 3OBT SLB 6.08466
606 3SJU NDP 6.09319
607 4USR FAD 6.09418
608 5MIT NAP 6.11621
609 5MIT FAD 6.11621
610 1G60 SAM 6.15385
611 3VYW SAM 6.16883
612 5T67 JHZ 6.34921
613 5T67 SAH 6.34921
614 3HDY GDU 6.34921
615 3HDY FDA 6.34921
616 3HDY FAD 6.34921
617 2EFJ SAH 6.34921
618 1YQZ FAD 6.34921
619 3GD4 FAD 6.34921
620 3GD4 NAD 6.34921
621 3E1T FAD 6.34921
622 1MUU NAD 6.34921
623 6H3O FAD 6.34921
624 3FPF TNA 6.37584
625 3FPF MTA 6.37584
626 4YT4 FE9 6.4
627 2EG5 SAH 6.45161
628 6C5B SAH 6.45161
629 4L2I FAD 6.46388
630 1CF2 NAP 6.52819
631 2PWY SAH 6.58915
632 1UAY ADN 6.61157
633 3G5S FAD 6.61376
634 4RSL FAD 6.61376
635 4K5S PM0 6.61376
636 4K5S FAD 6.61376
637 1I1N SAH 6.63717
638 3P2E SAH 6.66667
639 5GWX SAR 6.69014
640 5GWX SAM 6.69014
641 5WP5 SAH 6.72098
642 2ZIF SAM 6.73401
643 3EWP APR 6.77966
644 1UXG NAD 6.79612
645 1UXG FUM 6.79612
646 4Y30 SAH 6.83761
647 4Y30 49L 6.83761
648 4RVG SAM 6.87831
649 4RVG TYD 6.87831
650 4E70 N7I 6.87831
651 2WA2 SAM 6.88406
652 3AD8 NAD 6.89655
653 3AD8 FAD 6.89655
654 3AD8 PYC 6.89655
655 2VDV SAM 6.91057
656 3TKA SAM 6.91643
657 4PNE SAH 6.95364
658 1E6E FAD 7.03125
659 4YAC NAI 7.07071
660 2WK1 SAH 7.0922
661 6IS0 SAH 7.14286
662 2QA1 FAD 7.14286
663 4II2 ATP 7.22892
664 4URF NAD 7.25806
665 5LOG SAH 7.29614
666 1KYQ NAD 7.29927
667 1NFQ NAI 7.30769
668 3PT9 SAH 7.40741
669 1REO FAD 7.40741
670 4IWN GEK 7.42358
671 4ZCC NAI 7.44048
672 4ZCC FAD 7.44048
673 1EFV FAD 7.45098
674 1EFV AMP 7.45098
675 1R18 SAH 7.48899
676 5L95 AMP 7.5
677 4ONQ SFG 7.56302
678 3DUW SAH 7.62332
679 3WDM ADN 7.66284
680 4CQM NAP 7.66284
681 5FWA J7C 7.67196
682 3EYA FAD 7.67196
683 3GF4 FAD 7.69231
684 5E8J SAH 7.69231
685 3GF4 UPG 7.69231
686 5E9W SAH 7.69231
687 6ARJ BW4 7.73639
688 6ARJ SAH 7.73639
689 5DX8 SFG 7.73639
690 5DWQ SFG 7.73639
691 5DX1 SFG 7.73639
692 5DXA SFG 7.73639
693 5DX0 SFG 7.73639
694 3QFA FAD 7.75862
695 4NTC FAD 7.76119
696 3O7W SAM 7.82313
697 2VYN NAD 7.85498
698 3S5W FAD 7.93651
699 1UWK URO 7.93651
700 1UWK NAD 7.93651
701 6F97 FAD 7.93651
702 5KMS FAD 7.93651
703 5KMS NAD 7.93651
704 5MZI FYK 7.93651
705 5MZI FAD 7.93651
706 1JNR FAD 7.93651
707 4FC7 NAP 7.94224
708 4FC7 COA 7.94224
709 1KPH SAH 8.01394
710 1KPG SAH 8.01394
711 4GUS FAD 8.06452
712 3A27 SAM 8.08823
713 1JQ3 AAT 8.10811
714 1XHC FAD 8.17439
715 1RSG FAD 8.20106
716 1YY5 FAD 8.20106
717 5TS5 FAD 8.20106
718 2Q28 ADP 8.20106
719 5JAQ NAI 8.20106
720 5EEH P9P 8.24468
721 5EEH SAH 8.24468
722 3ELW GP3 8.33333
723 3ELW SAM 8.33333
724 1O97 FAD 8.33333
725 1O97 AMP 8.33333
726 1F3L SAH 8.41121
727 6ECU SAH 8.5443
728 6ECW SAH 8.57143
729 3L4S 3PG 8.63095
730 3L4S NAD 8.63095
731 2WSB NAD 8.66142
732 3TKY SAH 8.69565
733 5ODQ FAD 8.69565
734 1RJD SAM 8.73016
735 1RP0 AHZ 8.80282
736 5UFN SAH 8.82353
737 1Q0S SAH 8.88031
738 4YUW 4JU 8.88158
739 4YUW S4M 8.88158
740 5UR0 NAD 8.88252
741 5FUB SAH 8.90208
742 2JJQ SAH 8.99471
743 1KNR FAD 8.99471
744 5ZZ6 ADP 9.13461
745 5ZZ6 NAD 9.13461
746 1U2Z SAH 9.25926
747 2YG3 FAD 9.25926
748 3H2B SAH 9.35961
749 4POO SAM 9.5
750 5YJF SAH 9.50704
751 5YJF 8WO 9.50704
752 1NME 159 9.58904
753 2HMT NAI 9.72222
754 1FEC FAD 9.78836
755 5JCA FAD 9.85915
756 5JCA NDP 9.85915
757 1S7G APR 9.88142
758 2AQJ FAD 10.0529
759 2AQJ TRP 10.0529
760 2JAH NDP 10.1215
761 2B4Q NAP 10.1449
762 5N5D SAM 10.177
763 5W7K SAH 10.2564
764 1JQD SAH 10.274
765 2AOT SAH 10.274
766 1JQD HSM 10.274
767 5MBX SP5 10.3175
768 5MBX FAD 10.3175
769 3RNM FAD 10.3448
770 4QTU SAM 10.3704
771 5CUQ NSC 10.4869
772 5HJM MTA 10.5114
773 4EIP FAD 10.582
774 1DJL NAP 10.628
775 1FL2 FAD 10.6452
776 1KOL NAD 10.804
777 1DJN ADP 10.8466
778 1O94 ADP 10.8466
779 5WS9 AMP 10.8466
780 3QV1 NAD 10.9756
781 5EIN NAP 11.1111
782 4YMH SAH 11.25
783 2YX1 SFG 11.3095
784 3GEG NAD 11.336
785 5YJI SAH 11.6197
786 5YJI 8WO 11.6197
787 1Z3C SA8 11.745
788 5NMX FAD 11.9048
789 5NMX NAP 11.9048
790 2IZ1 ATR 11.9048
791 1D4O NAP 11.9565
792 4J56 FAD 12.2807
793 4EUE NAI 12.4339
794 3LCC SAH 12.766
795 6BJO DUY 12.8
796 2YVJ FAD 12.844
797 1GEG NAD 12.8906
798 6F5Z SAH 13.1148
799 1ZGA SAH 13.1653
800 2ZXI FAD 13.4921
801 1UP7 NAD 13.4921
802 1WY7 SAH 13.5266
803 4NBW NAD 14.0078
804 4GLL NAD 14.2433
805 3O03 NAP 14.7766
806 4XZ3 COA 14.7826
807 4D42 NAP 14.8936
808 4D42 W0I 14.8936
809 5FA8 SAM 14.9068
810 4HXY NDP 15.0685
811 2OBF SAH 15.2249
812 2OBF F83 15.2249
813 1TZD ADP 15.2727
814 1TPY SAH 15.331
815 2FKA BEF 15.5039
816 3SJ7 NDP 15.873
817 4XYM COA 16.087
818 1DSS NAD 16.8168
819 3C3Y SAH 17.2996
820 1VE3 SAM 17.6211
821 4RDN 6MD 17.9641
822 3PPQ CHT 18.328
823 4OBW SAM 18.677
824 3LKZ SFG 19.0031
825 3Q87 SAM 20.5882
826 4EMJ FAD 21.4953
827 2F5Z FAD 21.875
828 5M58 SAH 23.0435
829 5ZW3 SAH 23.5556
830 1L1E SAH 23.6934
Pocket No.: 2; Query (leader) PDB : 2EJU; Ligand: SAH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2eju.bio2) has 21 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 2EJU; Ligand: SAH; Similar sites found with APoc: 3
This union binding pocket(no: 3) in the query (biounit: 2eju.bio1) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 5ICE SAH 2.27273
2 4A05 CBI 3.2967
3 4GUT FAD 8.06452
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