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Receptor
PDB id Resolution Class Description Source Keywords
2EG5 2.2 Å EC: 2.1.1.- THE STRUCTURE OF XANTHOSINE METHYLTRANSFERASE COFFEA CANEPHORA SAM-DEPENDANT N-METHYLTRANSFERASE XANTHOSINE SAH TRANSFER
Ref.: THE STRUCTURE OF TWO N-METHYLTRANSFERASES FROM THE BIOSYNTHETIC PATHWAY PLANT PHYSIOL. V. 144 879 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAH A:501;
C:1501;
E:2501;
G:3501;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
XTS A:502;
C:1502;
E:2502;
G:3502;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
284.225 C10 H12 N4 O6 c1nc2...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2EG5 2.2 Å EC: 2.1.1.- THE STRUCTURE OF XANTHOSINE METHYLTRANSFERASE COFFEA CANEPHORA SAM-DEPENDANT N-METHYLTRANSFERASE XANTHOSINE SAH TRANSFER
Ref.: THE STRUCTURE OF TWO N-METHYLTRANSFERASES FROM THE BIOSYNTHETIC PATHWAY PLANT PHYSIOL. V. 144 879 2007
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 60 families.
1 2EG5 - XTS C10 H12 N4 O6 c1nc2c(n1[....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 54 families.
1 2EG5 - XTS C10 H12 N4 O6 c1nc2c(n1[....
2 2EFJ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 47 families.
1 2EG5 - XTS C10 H12 N4 O6 c1nc2c(n1[....
2 2EFJ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Ligand no: 2; Ligand: XTS; Similar ligands found: 7
No: Ligand ECFP6 Tc MDL keys Tc
1 XTS 1 1
2 13A 0.565217 0.810127
3 GMP 0.472973 0.913043
4 NOS 0.445946 0.910448
5 MZR 0.42029 0.835821
6 93A 0.416667 0.768293
7 6CG 0.411765 0.782051
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2EG5; Ligand: XTS; Similar sites found with APoc: 26
This union binding pocket(no: 1) in the query (biounit: 2eg5.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 1GCK ASP PLP 1.6129
2 5HSA FAS 2.15054
3 2OVD DAO 2.74725
4 5DRB 5FJ 2.74914
5 5A8E XTK 3.49206
6 3KAL HGS 3.76344
7 2YVE MBT 3.78378
8 3BQD DAY 3.92157
9 4I9B 1KA 4.30108
10 1J78 OLA 4.30108
11 2NVA PL2 4.30108
12 2WUF KEM 4.811
13 5IXK 6EW 4.82456
14 5HK9 64O 5.64784
15 1Y9Q MED 5.72917
16 2YN4 39J 7.20339
17 5C1M OLC 8
18 4UMJ BFQ 8.10811
19 3F3E LEU 8.33333
20 3UVD MB3 8.87097
21 3KFC 61X 9.09091
22 5BWD FUM 11.6667
23 5JNW 6LJ 13.8365
24 5E5U MLI 14.3939
25 4OIV XX9 15.0442
26 6C8R EQV 48.9247
Pocket No.: 2; Query (leader) PDB : 2EG5; Ligand: SAH; Similar sites found with APoc: 771
This union binding pocket(no: 2) in the query (biounit: 2eg5.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 4V3C C 1.07527
2 5N5D SAM 1.32743
3 3VSE SAH 1.34409
4 5TTJ FAD 1.34409
5 4FWE FAD 1.34409
6 2IHK CSF 1.34409
7 1KNR FAD 1.34409
8 1KOL NAD 1.34409
9 2PXX SAH 1.39535
10 1UDB UFG 1.47929
11 1UDB NAD 1.47929
12 4PLT NAI 1.51057
13 2WSB NAD 1.5748
14 2Q0L FAD 1.60772
15 4KRG SAH 1.6129
16 1FP1 SAH 1.6129
17 3QOX SAH 1.6129
18 1BZL GCG 1.6129
19 1BZL FAD 1.6129
20 1REO FAD 1.6129
21 2Z3Y F2N 1.6129
22 1SQF SAM 1.6129
23 4AP3 NAP 1.6129
24 4AP3 FAD 1.6129
25 3NTD FAD 1.6129
26 3NTA FAD 1.6129
27 3NT6 FAD 1.6129
28 1GQ2 NAP 1.6129
29 2GMH FAD 1.6129
30 2WET FAD 1.6129
31 4X9M FAD 1.6129
32 6C4N NAP 1.6129
33 2JAH NDP 1.61943
34 2JAP NDP 1.61943
35 5DF1 NAP 1.63043
36 5DF1 58X 1.63043
37 3P9C SAH 1.64835
38 1H2B NAJ 1.67131
39 5UR0 NAD 1.7192
40 3TKA SAM 1.72911
41 6C5B SAH 1.75953
42 4ZCC NAI 1.78571
43 4ZCC FAD 1.78571
44 5MW4 5JU 1.79641
45 3CMC NAD 1.79641
46 5KVA SAM 1.79856
47 6GAS FAD 1.81269
48 5O42 BGC 1.82482
49 5O42 9JW 1.82482
50 5O42 NAD 1.82482
51 3AYI HCI 1.88172
52 3AYI FAD 1.88172
53 4C3Y FAD 1.88172
54 1V5F TPP 1.88172
55 1V5F FAD 1.88172
56 4C3Y ANB 1.88172
57 1NAA ABL 1.88172
58 1NAA 6FA 1.88172
59 4EIP FAD 1.88172
60 2Y6Q I7T 1.88172
61 3G5S FAD 1.88172
62 2QA1 FAD 1.88172
63 1DJN ADP 1.88172
64 5Y77 FAD 1.88172
65 4R84 CSF 1.88172
66 2FNU PMP UD1 1.88172
67 4ZUL UN1 1.88172
68 1I8T FAD 1.90736
69 1X1T NAD 1.92308
70 1Q0S SAH 1.9305
71 1FK8 NAD 1.94553
72 1PL6 572 1.96629
73 1PL6 NAD 1.96629
74 4A6D SAM 1.983
75 1ZK4 NAP 1.99203
76 1ZK4 AC0 1.99203
77 6GKV SAH 1.9943
78 5N0J FAD 1.9943
79 5BSZ SAH 2
80 6ARJ BW4 2.00573
81 6ARJ SAH 2.00573
82 5DX8 SFG 2.00573
83 5DXA SFG 2.00573
84 5DX1 SFG 2.00573
85 6GAR FAD 2.00573
86 3QJ4 FAD 2.04678
87 3B20 NAD 2.0649
88 5JGL SAM 2.07612
89 3C3Y SAH 2.1097
90 5MPT SAH 2.15054
91 3NJ4 AFX 2.15054
92 3HDY GDU 2.15054
93 3HDY FDA 2.15054
94 3HDY FAD 2.15054
95 2RAB NAD 2.15054
96 5HSA FAS 2.15054
97 3NJ4 NAD 2.15054
98 2RAB FAD 2.15054
99 1GPE FAD 2.15054
100 1YQZ FAD 2.15054
101 2CDU FAD 2.15054
102 6F97 FAD 2.15054
103 1ELI PYC 2.15054
104 5VN0 FAD 2.15054
105 5VN0 NAI 2.15054
106 4KGD FAD 2.15054
107 5HXI FAD 2.15054
108 5HXI 5HN 2.15054
109 3E1T FAD 2.15054
110 4KGD TDP 2.15054
111 4CNK FAD 2.15054
112 4U8P UDP 2.15054
113 4U8P FDA 2.15054
114 3GMB FAD 2.15054
115 5KOX FAD 2.15054
116 5KOX RFP 2.15054
117 2ZXI FAD 2.15054
118 5MB4 NAG 2.15054
119 1GZ4 ATP 2.15054
120 2CDU ADP 2.15054
121 5MB4 NDG 2.15054
122 2CUL FAD 2.15517
123 1XHC FAD 2.17984
124 5YF1 8V0 2.20994
125 5YF1 SFG 2.20994
126 1RKX NAD 2.2409
127 1VL8 NAP 2.24719
128 5JY6 NAD 2.24719
129 5GT9 NAP 2.28137
130 3LST SAH 2.29885
131 1V59 FAD 2.30126
132 1V59 NAD 2.30126
133 2O07 SPD 2.30263
134 2O07 MTA 2.30263
135 3ZNN 4WL 2.30548
136 3ZNN FAD 2.30548
137 1NFQ NAI 2.30769
138 3A25 SAM 2.32558
139 5TWB FAD 2.32558
140 3A28 NAD 2.32558
141 3KLJ FAD 2.33766
142 2ZIF SAM 2.3569
143 1RJW ETF 2.35988
144 1XSE NDP 2.37288
145 5FEU NAP 2.4055
146 5X62 SAH 2.41935
147 4RVG TYD 2.41935
148 4RVG SAM 2.41935
149 5M67 NAD 2.41935
150 5M67 ADE 2.41935
151 5M67 3D1 2.41935
152 3SQP FAD 2.41935
153 2ZJ1 NAD 2.41935
154 2ZJ1 ARJ 2.41935
155 4HXY NDP 2.41935
156 3LXD FAD 2.41935
157 1X87 NAD 2.41935
158 2YVF NAD 2.41935
159 2YVF FAD 2.41935
160 3AXB PRO 2.41935
161 3AXB FAD 2.41935
162 2YVJ FAD 2.41935
163 2IVD FAD 2.41935
164 2Q1S NAI 2.41935
165 1U8X NAD 2.41935
166 1UP7 NAD 2.41935
167 1E5Q NDP 2.41935
168 5JE0 SAH 2.42915
169 5JE0 AZ8 2.42915
170 3HB5 NAP 2.44648
171 5NA1 FAD 2.45098
172 3H2B SAH 2.46305
173 1OMO NAD 2.48447
174 2A92 NAI 2.49221
175 3AB1 FAD 2.5
176 3CIF G3H 2.50696
177 3CIF NAD 2.50696
178 3T31 FAD 2.51716
179 3T31 DCQ 2.51716
180 1ZGA SAH 2.52101
181 3EVF SAH 2.52708
182 3EVF GTA 2.52708
183 6ECU SAH 2.53165
184 6ECW SAH 2.53968
185 2BZG SAH 2.58621
186 4GLL NAD 2.67062
187 3G2O SAM 2.67559
188 4NTC FAD 2.68657
189 4AZW SAM 2.68817
190 3L9W AMP 2.68817
191 3L9W GSH 2.68817
192 4Z24 FAD 2.68817
193 5KMS FAD 2.68817
194 4DCM SAM 2.68817
195 6F3N ADN 2.68817
196 6F3N NAD 2.68817
197 6F3M NAD 2.68817
198 3S1S SAH 2.68817
199 5JCM NAD 2.68817
200 5JCM ISD 2.68817
201 5JCM FAD 2.68817
202 3CGB FAD 2.68817
203 1Q1R FAD 2.68817
204 4E70 N7I 2.68817
205 5KMS NAD 2.68817
206 2IV2 MGD 2.68817
207 3BGD SAH 2.69231
208 3BGD PM6 2.69231
209 3HVJ 705 2.71493
210 5FFF 5XC 2.72374
211 5FFF NAP 2.72374
212 5DRB 5FJ 2.74914
213 4XUC SAM 2.75229
214 4XUC 43G 2.75229
215 4FN4 NAD 2.75591
216 1L1E SAH 2.78746
217 5UAV TFB 2.79503
218 5UAV NDP 2.79503
219 1M2K APR 2.81124
220 4URF NAD 2.82258
221 1EDO NAP 2.86885
222 1ORR NAD 2.88184
223 1LLU NAD 2.92398
224 5THQ NDP 2.94118
225 1XDS SAM 2.95699
226 1UWK NAD 2.95699
227 1UWK URO 2.95699
228 5FWA J7C 2.95699
229 4YNU LGC 2.95699
230 4YNU FAD 2.95699
231 3GD4 NAD 2.95699
232 3GD4 FAD 2.95699
233 3C6K SPD 2.95699
234 5W7R 9Z7 2.95699
235 3NKS FAD 2.95699
236 5J5Z FAD 2.95699
237 3C6K MTA 2.95699
238 5W7R SAH 2.95699
239 3EYA FAD 2.95699
240 1E1M FAD 2.95699
241 1E1M NAP 2.95699
242 2XVE FAD 2.95699
243 2XVF FAD 2.95699
244 5J7X FAD 2.95699
245 3V1U NAD 2.95699
246 6F7L FAD 2.95699
247 4YUW 4JU 2.96053
248 4YUW S4M 2.96053
249 5XNC MTA 2.96496
250 4Z0H NAD 2.99401
251 5BW4 SAM 2.99625
252 3FZG SAM 3
253 1CER NAD 3.02115
254 2V6G NAP 3.02198
255 2DTX BMA 3.0303
256 1E3W NAD 3.06513
257 5LD5 NAD 3.07263
258 1E6W NAD 3.07692
259 2AE2 PTO 3.07692
260 2AE2 NAP 3.07692
261 1BXK NAD 3.09859
262 3OID NDP 3.10078
263 2CIG 1DG 3.14465
264 3CH6 311 3.14685
265 3CH6 NAP 3.14685
266 2Q46 NAP 3.16206
267 5TUF TDC 3.17848
268 5TUF FAD 3.17848
269 4D42 NAP 3.19149
270 4D42 W0I 3.19149
271 3OU2 SAH 3.21101
272 5WP4 SAH 3.22581
273 3JWH SAH 3.22581
274 1QZZ SAM 3.22581
275 5JAQ NAI 3.22581
276 4EMI NAD 3.22581
277 4EMI FAD 3.22581
278 3UCL NAP 3.22581
279 3UCL CYH 3.22581
280 3UCL FAD 3.22581
281 2NPX FAD 3.22581
282 2NPX NAD 3.22581
283 4JDR FAD 3.22581
284 6ER9 NAP 3.22581
285 2C31 ADP 3.22581
286 2C31 TZD 3.22581
287 6ER9 FAD 3.22581
288 6EL3 NAP 3.22581
289 3OJO NAD 3.22581
290 2IZ1 ATR 3.22581
291 1SC6 NAD 3.22581
292 4XYM COA 3.23276
293 4XZ3 COA 3.23276
294 1R6D DAU 3.2641
295 1R6D NAD 3.2641
296 6EQS BV8 3.27273
297 3RIY NAD 3.2967
298 2Q1W NAD 3.3033
299 2VYN NAD 3.32326
300 1GAD NAD 3.33333
301 4KIB SAH 3.36134
302 2Q7V FAD 3.38462
303 3EWP APR 3.38983
304 5J60 FAD 3.4375
305 2XOC ADP 3.44828
306 1KPG SAH 3.48432
307 1KPH SAH 3.48432
308 4R6W SAH 3.48837
309 4R6W PC 3.48837
310 5ERG SAM 3.49462
311 1Y8Q ATP 3.49462
312 3OND ADN 3.49462
313 3OND NAD 3.49462
314 5U8U FAD 3.49462
315 4RSL FAD 3.49462
316 3FPZ AHZ 3.49462
317 4DSG FAD 3.49462
318 4DSG UDP 3.49462
319 4MOP 2H5 3.49462
320 6FP4 FAD 3.49462
321 6FP4 E1T 3.49462
322 5GSN FAD 3.49462
323 5XHA FRU 3.49462
324 1S7G APR 3.55731
325 1S7G NAD 3.55731
326 4GKV NAD 3.57143
327 2QQF A1R 3.57143
328 2OD9 A1R NCA 3.57143
329 6BQ6 TER 3.62538
330 1JA9 NDP 3.64964
331 3QV1 NAD 3.65854
332 1AE1 NAP 3.663
333 3A27 SAM 3.67647
334 4CS9 AMP 3.7037
335 1SZD APR 3.7037
336 1OC2 TDX 3.73563
337 1OC2 NAD 3.73563
338 6B92 SAH 3.7415
339 1IY8 NAD 3.74532
340 2WPF FAD 3.76344
341 2WPF WPF 3.76344
342 3PT9 SAH 3.76344
343 1I2B NAD 3.76344
344 1I2B USQ 3.76344
345 1I2B UPG 3.76344
346 2A8X FAD 3.76344
347 1GET NAP 3.76344
348 1GET FAD 3.76344
349 4M52 FAD 3.76344
350 4YKG FAD 3.76344
351 1RM0 NAI 3.76344
352 1RM0 D6P 3.76344
353 3QFA FAD 3.76344
354 2C7G ODP 3.76344
355 2C7G FAD 3.76344
356 4AT0 FAD 3.76344
357 3IHG FAD 3.76344
358 1E3I CXF 3.76344
359 4K5S FAD 3.76344
360 4K5S PM0 3.76344
361 5MGZ SAH 3.81356
362 1TPY SAH 3.83275
363 4ZRN NAD 3.84615
364 4ZRN UPG 3.84615
365 5F90 GLA GAL 3.84615
366 5OJI NAP 3.84615
367 5OJI ISN 3.84615
368 3L4S 3PG 3.86905
369 3L4S NAD 3.86905
370 2I7C AAT 3.88693
371 4OBW SAM 3.89105
372 1BXG NAD 3.93258
373 1C1X NAD 3.94366
374 5MIT NAP 3.97554
375 5MIT FAD 3.97554
376 5HJM MTA 3.97727
377 1FEC FAD 4.03226
378 3LAD FAD 4.03226
379 2JB2 PHE 4.03226
380 2JB2 FAD 4.03226
381 4GUT FAD 4.03226
382 5BRT CH9 4.03226
383 5BRT FAD 4.03226
384 4GUS FAD 4.03226
385 4D7E FAD 4.03226
386 1CDO NAD 4.03226
387 3HU3 AGS 4.03226
388 3GEG NAD 4.04858
389 3NUG NAD 4.04858
390 6ECT SAM 4.04984
391 2VDV SAM 4.06504
392 1RLZ NAD 4.06504
393 1LTH NAD 4.07523
394 1BC5 SAH 4.08922
395 5BJX UDP 4.09836
396 5BJX NAD 4.09836
397 2BD0 NAP 4.09836
398 1DL5 SAH 4.10095
399 1KYZ SAH 4.10959
400 1KYZ FER 4.10959
401 3Q87 SAM 4.11765
402 3WV8 ATP 4.12844
403 4RDI ATP 4.16667
404 4RDH AMP 4.16667
405 2ZFU SAH 4.18605
406 5EJ2 NAD 4.22078
407 5JCA FAD 4.22535
408 6CI9 NAP 4.2471
409 2P41 SAH 4.2623
410 4N49 SAM 4.30108
411 4DMG SAM 4.30108
412 3CTY FAD 4.30108
413 1U2Z SAH 4.30108
414 3O03 NAP 4.30108
415 5NMX FAD 4.30108
416 5NMX NAP 4.30108
417 5MLR GRQ 4.30108
418 5MLR NAP 4.30108
419 1MUU NAD 4.30108
420 1G55 SAH 4.37318
421 6GFK SAH 4.38247
422 1NW5 SAM 4.38871
423 3U31 NAD 4.48276
424 5E9W SAH 4.48718
425 5E8J SAH 4.48718
426 1FL2 FAD 4.51613
427 1SB8 NAD 4.54545
428 1SB8 UD2 4.54545
429 3MAG SAH 4.56026
430 3PFG SAM 4.56274
431 3PFG TLO 4.56274
432 5T67 SAH 4.56989
433 5T67 JHZ 4.56989
434 3GDN HBX 4.56989
435 3GDN FAD 4.56989
436 1PN0 FAD 4.56989
437 1PN0 IPH 4.56989
438 6H3O FAD 4.56989
439 2IID PHE 4.56989
440 2IID FAD 4.56989
441 5EB4 FAD 4.56989
442 5WGR FAD 4.56989
443 1U1I NAD 4.56989
444 1MV8 NAD 4.56989
445 3MQ2 SAH 4.58716
446 3K1X DBX 4.61538
447 5A3B APR 4.62046
448 4JK3 NAD 4.6332
449 4J4H NAI 4.6332
450 4J4H 1J1 4.6332
451 1OAA OAA 4.6332
452 4PNE SAH 4.63576
453 1GEG NAD 4.6875
454 5F7J ADE 4.6875
455 5U19 827 4.69208
456 5U19 SAH 4.69208
457 1BDB NAD 4.69314
458 4D79 ATP 4.71014
459 3MCT SAH 4.7138
460 3EVG SAH 4.72727
461 4ZA2 NAD 4.74308
462 5LW0 AR6 4.7619
463 2OFW ADX 4.80769
464 1HDG NAD 4.81928
465 5ICE SAH 4.82955
466 5ICE 2H4 4.82955
467 5G3U FDA 4.83871
468 5G3U ITW 4.83871
469 1GTE FAD 4.83871
470 1MO9 KPC 4.83871
471 1MO9 FAD 4.83871
472 4XQC 13D 4.83871
473 4XQC NAD 4.83871
474 2FZW NAD 4.83871
475 1R18 SAH 4.84582
476 5D4V SAH 4.85075
477 2HMT NAI 4.86111
478 1EK6 NAI 4.88506
479 1EK6 UPG 4.88506
480 5K7U SAM 4.88889
481 1PR9 NAP 4.91803
482 3D3W NAP 4.91803
483 4POO SAM 5
484 1SBR VIB 5
485 2XVM SAH 5.02513
486 2WA2 SAM 5.07246
487 5JJR SAH 5.10753
488 1YBH FAD 5.10753
489 4HA6 FAD 5.10753
490 3GF4 UPG 5.10753
491 1QO8 FAD 5.10753
492 4D04 NAP 5.10753
493 4D04 FAD 5.10753
494 3GF4 FAD 5.10753
495 5UAO FAD 5.10753
496 4TM3 FAD 5.10753
497 6F9Q NAD 5.14706
498 5LOG SAH 5.15021
499 2UYQ SAM 5.16129
500 3RNM FAD 5.17241
501 4BLW AMP 5.19031
502 4BLW SAH 5.19031
503 1ZBQ NAD 5.19878
504 3H9E NAD 5.20231
505 3AY6 BGC 5.20446
506 3AY6 NAI 5.20446
507 4TQG NDP 5.26316
508 4PIO AVI 5.26316
509 4PIO SAH 5.26316
510 6HOY AR6 5.29801
511 6HOY TSN 5.29801
512 1QAN SAH 5.32787
513 2YX1 SFG 5.35714
514 4RPL FAD 5.37634
515 4RPL 3UC 5.37634
516 2NVK FAD 5.37634
517 5BVA FAD 5.37634
518 2GN4 NDP 5.37634
519 4IV9 FAD 5.37634
520 1LVL FAD 5.37634
521 3Q9T FAY 5.37634
522 2GN4 UD1 5.37634
523 1LVL NAD 5.37634
524 5GM1 SAH 5.38721
525 6FDF SAH 5.38922
526 3ZG6 APR 5.40541
527 3TKY SAH 5.43478
528 4NBW NAD 5.44747
529 5UFN SAH 5.46218
530 1E6E FAD 5.46875
531 1JQD SAH 5.47945
532 2AOT SAH 5.47945
533 1JQD HSM 5.47945
534 3ABI NAD 5.47945
535 1XCL SAH 5.53191
536 4J36 FAD 5.54217
537 3T7S SAM 5.59701
538 3LKZ SFG 5.60748
539 2GDZ NAD 5.61798
540 4KRI SAH 5.64516
541 4TXI FAD 5.64516
542 2BRY FAD 5.64516
543 2YG3 FAD 5.64516
544 1FP2 SAH 5.68182
545 1FP2 HMO 5.68182
546 1O97 FAD 5.68182
547 1O97 AMP 5.68182
548 1O94 ADP 5.68182
549 3FPF TNA 5.7047
550 3FPF MTA 5.7047
551 1DSS NAD 5.70571
552 1VE3 SAM 5.72687
553 4CQM NAP 5.74713
554 3P2E SAH 5.77778
555 1UXG NAD 5.82524
556 1UXG FUM 5.82524
557 4X7Y SAH 5.83942
558 5YEC ATP 5.88235
559 5TS5 FAD 5.91398
560 6DEN FAD 5.91398
561 6DEN TP9 5.91398
562 6DEN G8A 5.91398
563 3ICT FAD 5.91398
564 2DKH 3HB 5.91398
565 2DKH FAD 5.91398
566 3ICR FAD 5.91398
567 3ICS FAD 5.91398
568 2PT9 2MH 5.919
569 2PT9 S4M 5.919
570 3GWZ SAH 5.96206
571 3GXO SAH 5.96206
572 2DPM SAM 5.98592
573 2CFC NAD 6
574 2EWM NAD 6.0241
575 1U7T TDT 6.13027
576 1U7T NAD 6.13027
577 2DT5 NAD 6.16114
578 5KOK SAH 6.1828
579 5KOK S9T 6.1828
580 5KOK R9T 6.1828
581 4GQB 0XU 6.1828
582 5FA5 MTA 6.1828
583 1GY8 NAD 6.1828
584 1VQW FAD 6.1828
585 2GV8 FAD 6.1828
586 2GVC FAD 6.1828
587 3RHJ NAP 6.1828
588 1Z45 NAD 6.1828
589 4YAG NAI 6.22837
590 5YSS NAD 6.25
591 1AOE GW3 6.25
592 1AOE NDP 6.25
593 3OZ2 FAD 6.29723
594 1Z3C SA8 6.37584
595 3GCZ SAM 6.38298
596 3QPB URA 6.38298
597 1WVG APR 6.40669
598 5W7M SAH 6.41026
599 1I9G SAM 6.42857
600 2EJU SAH 6.45161
601 2HQM FAD 6.45161
602 4BV6 FAD 6.45161
603 1V8B NAD 6.45161
604 4MIG G3F 6.45161
605 3LU1 NAD 6.45161
606 4YCA NDP 6.46258
607 2RH4 EMO 6.4982
608 1P1C SAH 6.53266
609 5DNK SAH 6.72043
610 4UCI SAM 6.72043
611 1VKO NAD 6.72043
612 1L3I SAH 6.77083
613 5OOH 9ZZ 6.79612
614 5OOH NAP 6.79612
615 5FUB SAH 6.82493
616 4YRY FAD 6.88406
617 4YRY NAD 6.88406
618 1GZ6 NAI 6.89655
619 1NM5 NAD 6.89655
620 1NM5 NAP 6.89655
621 5O4J 9KH 6.93431
622 5O4J PJL 6.93431
623 5O4J SAH 6.93431
624 5E72 SAM 6.93642
625 6DNT NAD 6.97674
626 4EUE NAI 6.98925
627 5THY SAH 6.98925
628 2VVL FAD 6.98925
629 2VVM FAD 6.98925
630 1PS9 FAD 6.98925
631 2WOX NDP 6.98925
632 5GWX SAM 7.04225
633 5GWX SAR 7.04225
634 2PX8 SAH 7.0632
635 1G0N PHH 7.06714
636 1G0N NDP 7.06714
637 1XHL NDP 7.07071
638 1GR0 NAD 7.08447
639 3RJ5 NAD 7.08661
640 2HNK SAH 7.11297
641 5CUQ NSC 7.11611
642 3RFV NAI 7.11611
643 1XKQ NDP 7.14286
644 3H8V ATP 7.19178
645 4USQ FAD 7.20222
646 3QVP FAD 7.25806
647 2Q28 ADP 7.25806
648 5BUK FAD 7.25806
649 5ULP KB1 7.46269
650 5E1M PRO PRO LYS ARG ILE ALA 7.46888
651 5E1M SAH 7.46888
652 1XTP SAI 7.48031
653 2JHP SAH 7.52688
654 4G5H UD7 7.52688
655 4G5H NAP 7.52688
656 2BGM NAJ 7.55396
657 5Y1G AKB 7.62195
658 5Y1G NAD 7.62195
659 4BUZ NAD 7.72358
660 4BUZ OCZ 7.72358
661 4BUZ OAD 7.72358
662 1YC5 NCA 7.72358
663 5YJI 8WO 7.74648
664 5YJI SAH 7.74648
665 3QWI NAP 7.77778
666 3QWI CUE 7.77778
667 1PNO NAP 7.77778
668 5THZ SAH 7.7957
669 4ITU 1HS 7.7957
670 4ITU NAI 7.7957
671 3U4C NDP 7.82918
672 4JNA FAD 7.94118
673 3BXO SAM 7.94979
674 2OOR TXP 8.04598
675 6F5Z SAH 8.19672
676 4Y9D NAI 8.19672
677 5JE8 NAD 8.27815
678 5F8F SFG 8.33333
679 6B3A SAM 8.33333
680 1ZEM NAD 8.39695
681 1I1N SAH 8.40708
682 5YJF SAH 8.4507
683 5YJF 8WO 8.4507
684 5Z2L NDP 8.57143
685 1KYQ NAD 8.75912
686 4NBU NAI 8.8
687 2PWY SAH 8.91473
688 5ZQ4 AMP 8.97436
689 3AD8 FAD 9.13978
690 3AD8 PYC 9.13978
691 5Z75 NAD 9.13978
692 6BWL NAD 9.14634
693 5FA8 SAM 9.31677
694 3ELW SAM 9.33333
695 3ELW GP3 9.33333
696 5K0A FAD 9.39394
697 2PZM NAD 9.39394
698 2PZM UDP 9.39394
699 5X68 FAD 9.4086
700 3VYW SAM 9.41558
701 1G60 SAM 9.61539
702 3WMX NAD 9.77654
703 2UXR ICT 9.94624
704 4NEC SAH 10.2273
705 1F3L SAH 10.2804
706 4K26 SFF 10.5072
707 4K26 NDP 10.5072
708 1G8K MGD 10.5263
709 3DXY SAM 10.5505
710 1UAY ADN 10.7438
711 1PJS NAD 10.7527
712 1RYI FAD 10.7527
713 1EFV FAD 10.7937
714 1EFV AMP 10.7937
715 4MO2 FDA 10.8696
716 4MO2 FAD 10.8696
717 4REP FAD 11.0215
718 4NTD FAD 11.1765
719 1T9D P25 11.2903
720 1T9D 1MM 11.2903
721 1T9D PYD 11.2903
722 5WKC FAD 11.2903
723 1T9D FAD 11.2903
724 3WDM ADN 11.4943
725 1JNR FAD 11.5591
726 3UOY NAP 11.5591
727 3UOY FAD 11.5591
728 5XLX SAH 11.7021
729 1NJR XYL 12.3239
730 3S5W FAD 12.3656
731 1JQ3 AAT 12.5
732 2YY7 NAD 12.5
733 1RP0 AHZ 12.6761
734 4LWP SAH 12.7717
735 1LSS NAD 12.8571
736 1JG3 ADN 13.1915
737 2A14 SAH 13.308
738 3ZV6 4HB 13.5231
739 3ZV6 NAD 13.5231
740 4YMH SAH 13.75
741 1YXM ADE 14.1914
742 5E5U MLT 14.3939
743 6DUB SAH 14.4144
744 5W7K SAH 14.7436
745 1DJL NAP 14.9758
746 2OBF SAH 15.2249
747 2OBF F83 15.2249
748 5FTW SAH 15.625
749 3SJ7 NDP 15.873
750 1VMK GUN 15.8845
751 4II2 ATP 15.9509
752 1D4O NAP 16.8478
753 3LZW FAD 17.1687
754 3LZW NAP 17.1687
755 5L95 AMP 17.5
756 3MB5 SAM 17.6471
757 4L2I FAD 18.6312
758 4HSU FAD 20
759 3LCV SAM 20.2847
760 4J56 FAD 21.9298
761 2GAG NAD 25.2525
762 2GAG FAD 25.2525
763 2GAG FOA 25.2525
764 2F5Z FAD 28.125
765 3G08 FEE 29.2929
766 5DX0 SFG 30
767 5DWQ SFG 30
768 5F2K OCA 38.8587
769 5F2K SAH 38.8587
770 6C8R SAH 48.9247
771 6C8R EQV 48.9247
Pocket No.: 3; Query (leader) PDB : 2EG5; Ligand: XTS; Similar sites found with APoc: 6
This union binding pocket(no: 3) in the query (biounit: 2eg5.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 1RO7 CSF 2.3166
2 4D52 GXL 4.12698
3 4D52 GIV 4.12698
4 1WEI ADE 4.88889
5 5G5W R8C 7.5
6 1WMA AB3 9.05797
Pocket No.: 4; Query (leader) PDB : 2EG5; Ligand: SAH; Similar sites found with APoc: 65
This union binding pocket(no: 4) in the query (biounit: 2eg5.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 5FJN BE2 1.34409
2 5FJN FAD 1.34409
3 4YAC NAI 1.6835
4 2Y6Q FAD 1.88172
5 3UMV FAD 1.88172
6 1VPV PLM 2
7 1ZK7 FAD 2.15054
8 2FR1 NDP 2.15054
9 5EOW FAD 2.15054
10 1W8D NAP 2.31788
11 1W73 NAP 2.31788
12 1W6U NAP 2.31788
13 3X0V FAD 2.41935
14 4UP3 FAD 2.54777
15 4J5R A1R 2.73973
16 4USR FAD 2.77008
17 5OJ7 AR6 2.7972
18 1R37 NAD 2.88184
19 5ZI2 ADP 2.89855
20 3VBK 0FX 2.92683
21 5OC1 FAD 2.95699
22 3CGD FAD 2.95699
23 6CEP OXM 2.99401
24 6CEP NAD 2.99401
25 1EU1 MGD 3.22581
26 3A4V PYR 3.47003
27 3A4V NAD 3.47003
28 4B63 FAD 3.49462
29 4B63 NAP 3.49462
30 4B63 ORN 3.49462
31 5K4W NAI 3.73832
32 5K4W THR 3.73832
33 4M52 M52 3.76344
34 3HAZ FAD 4.30108
35 1T26 NAI 4.34783
36 1T26 GBD 4.34783
37 1MXH DHF 4.34783
38 1MXH NAP 4.34783
39 2RGJ FAD 4.56989
40 3SJU NDP 4.6595
41 5I39 FAD 4.83871
42 1H82 GZZ 5.10753
43 1H82 FAD 5.10753
44 4J36 1HR 5.54217
45 2RGO FAD 5.64516
46 1GEE NAD 5.74713
47 5GWT NAD 5.7554
48 5GWT SIN 5.7554
49 4NBT NAD 5.83333
50 4CDN FAD 5.91398
51 5ZYN FAD 5.91398
52 4OPC FDA 6.1828
53 4OPC PGT 6.1828
54 1RSG FAD 6.45161
55 1D4D FAD 6.98925
56 2IVF MGD 7.52688
57 3MYZ TFX 8
58 1H5Q NAP 8.67924
59 3AD8 NAD 9.13978
60 2FKA BEF 9.30233
61 3VPH OXM 9.67742
62 3K7M FAD 10.7527
63 1RYI GOA 10.7527
64 3R1V AZB 14.9606
65 3QUZ QUV 29.2929
Pocket No.: 5; Query (leader) PDB : 2EG5; Ligand: XTS; Similar sites found with APoc: 5
This union binding pocket(no: 5) in the query (biounit: 2eg5.bio2) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 1SC6 NAD 3.22581
2 3Q9T FAY 5.37634
3 3CL7 HYN 6.49351
4 5F2K OCA 38.8587
5 5F2K SAH 38.8587
Pocket No.: 6; Query (leader) PDB : 2EG5; Ligand: SAH; Similar sites found with APoc: 7
This union binding pocket(no: 6) in the query (biounit: 2eg5.bio2) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 1YY5 FAD 1.07527
2 5JWC FAD 1.6129
3 3WGT FAD 2.30548
4 3WGT QSC 2.30548
5 5KKA 6V0 2.5641
6 5ZI2 NAD 2.89855
7 6AIN FAD 3.76344
Pocket No.: 7; Query (leader) PDB : 2EG5; Ligand: XTS; Similar sites found with APoc: 4
This union binding pocket(no: 7) in the query (biounit: 2eg5.bio2) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 5JE0 AZ8 2.42915
2 5JE0 SAH 2.42915
3 4P6X HCY 3.52941
4 1D6H COA 8.33333
Pocket No.: 8; Query (leader) PDB : 2EG5; Ligand: SAH; Similar sites found with APoc: 1
This union binding pocket(no: 8) in the query (biounit: 2eg5.bio2) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 1KEW NAD 3.87812
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