Receptor
PDB id Resolution Class Description Source Keywords
2E2R 1.6 Å NON-ENZYME: TRANSCRIPT_TRANSLATE CRYSTAL STRUCTURE OF HUMAN ESTROGEN-RELATED RECEPTOR GAMMA L BINDING DOMAIN COMPLEX WITH BISPHENOL A HOMO SAPIENS ERR GAMMA BPA NUCLEAR RECEPTOR TRANSCRIPTION
Ref.: STRUCTURAL EVIDENCE FOR ENDOCRINE DISRUPTOR BISPHEN BINDING TO HUMAN NUCLEAR RECEPTOR ERR{GAMMA} J.BIOCHEM.(TOKYO) V. 142 517 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
2OH A:1401;
Valid;
none;
Kd = 5.5 nM
228.286 C15 H16 O2 CC(C)...
GOL A:501;
A:502;
A:503;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2E2R 1.6 Å NON-ENZYME: TRANSCRIPT_TRANSLATE CRYSTAL STRUCTURE OF HUMAN ESTROGEN-RELATED RECEPTOR GAMMA L BINDING DOMAIN COMPLEX WITH BISPHENOL A HOMO SAPIENS ERR GAMMA BPA NUCLEAR RECEPTOR TRANSCRIPTION
Ref.: STRUCTURAL EVIDENCE FOR ENDOCRINE DISRUPTOR BISPHEN BINDING TO HUMAN NUCLEAR RECEPTOR ERR{GAMMA} J.BIOCHEM.(TOKYO) V. 142 517 2007
Members (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 257 families.
1 2ZAS ic50 = 13.9 nM 1OH C15 H16 O CC(C)(c1cc....
2 2EWP ic50 = 0.079 uM TXF C27 H31 N O3 CN(C)CCOc1....
3 1S9P - DES C18 H20 O2 CC/C(=C(/C....
4 2E2R Kd = 5.5 nM 2OH C15 H16 O2 CC(C)(c1cc....
5 2P7Z Kd = 0.262 uM OHT C26 H29 N O2 CC/C(=C(c1....
6 2GPU - OHT C26 H29 N O2 CC/C(=C(c1....
7 2P7A Kd = 0.788 uM 43M C7 H7 Cl O Cc1cc(ccc1....
8 2P7G Kd = 0.297 uM 2OH C15 H16 O2 CC(C)(c1cc....
9 1S9Q - OHT C26 H29 N O2 CC/C(=C(c1....
70% Homology Family (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 222 families.
1 2PJL ic50 = 190 nM 047 C23 H28 N2 Cc1ccc(cc1....
2 2ZAS ic50 = 13.9 nM 1OH C15 H16 O CC(C)(c1cc....
3 2EWP ic50 = 0.079 uM TXF C27 H31 N O3 CN(C)CCOc1....
4 1S9P - DES C18 H20 O2 CC/C(=C(/C....
5 2E2R Kd = 5.5 nM 2OH C15 H16 O2 CC(C)(c1cc....
6 2P7Z Kd = 0.262 uM OHT C26 H29 N O2 CC/C(=C(c1....
7 2GPU - OHT C26 H29 N O2 CC/C(=C(c1....
8 2P7A Kd = 0.788 uM 43M C7 H7 Cl O Cc1cc(ccc1....
9 2P7G Kd = 0.297 uM 2OH C15 H16 O2 CC(C)(c1cc....
10 1S9Q - OHT C26 H29 N O2 CC/C(=C(c1....
50% Homology Family (77)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 185 families.
1 3ERT - OHT C26 H29 N O2 CC/C(=C(c1....
2 1YIM ic50 = 1.5 nM CM4 C28 H31 N O4 C[C@@H]1c2....
3 1XP6 ic50 = 0.4 nM AIU C28 H31 N O4 S C[C@@H]1CN....
4 5FQT ic50 = 160 nM 7QN C23 H27 N O3 Cc1c(ccc2c....
5 4IW6 - 1GU C18 H15 F3 N2 O2 C=CCCn1c(c....
6 5FQV ic50 = 610 nM VQI C23 H27 N O3 Cc1cc2c(cc....
7 4IW8 - KN3 C19 H17 F3 N2 O2 CC(=CCn1c2....
8 5FQR ic50 = 26 nM QHG C22 H25 N O3 CC(C)CN1CC....
9 2IOG ic50 = 8 nM IOG C33 H39 N3 O3 C[C@H](CCc....
10 1GWQ Kd = 76 nM LYS ILE LEU HIS ARG LEU LEU GLN ASP n/a n/a
11 4IVW - 1GJ C21 H15 F3 N2 O2 c1ccc(cc1)....
12 5U2B - 6WV C24 H29 N O C[C@]12CC[....
13 4IUI - 1GQ C18 H17 F3 N2 O2 CCCCn1c2c(....
14 1XQC ic50 = 63 nM AEJ C29 H33 N3 O c1ccc(cc1)....
15 1UOM ic50 = 19 nM PTI C28 H32 N2 O2 c1ccc(cc1)....
16 1XP1 ic50 = 0.5 nM AIH C28 H31 N O4 S C[C@H]1CN(....
17 2QXS - RAL C28 H27 N O4 S c1cc(ccc1c....
18 2Q70 Ki = 8.3 nM DC8 C18 H16 F2 O3 c1cc(ccc1[....
19 2R6W Ki = 0.44 nM LLB C29 H29 N O4 S CC1CCN(CC1....
20 2QE4 Ki = 0.28 nM JJ3 C20 H22 O4 COCc1cc(cc....
21 5AK2 ic50 = 0.0039 uM 85Z C26 H19 F O5 Cc1cc(ccc1....
22 1XP9 ic50 = 1.3 nM AIJ C27 H29 N O4 S C[C@@H](CO....
23 4IV4 - 1GS C18 H17 F3 N2 O2 CC(C)Cn1c(....
24 2IOK ic50 = 1 nM IOK C26 H26 N2 O2 C[C@H](CCc....
25 3OSA - KN3 C19 H17 F3 N2 O2 CC(=CCn1c2....
26 5TN9 - 7EC C31 H32 Br N O6 S c1cc(ccc1C....
27 3UUC - 0D1 C14 H10 Cl2 O2 c1cc(ccc1C....
28 1GWR Kd = 250 nM ASN ALA LEU LEU ARG TYR LEU LEU ASP n/a n/a
29 4PP6 - LYS ILE LEU HIS ARG LEU LEU GLN ASP n/a n/a
30 2OUZ - C3D C28 H31 N O2 c1ccc(cc1)....
31 3OS9 - KN1 C17 H13 F3 N2 O2 C=CCn1c2c(....
32 1XPC ic50 = 1.7 nM AIT C27 H29 N O4 S C[C@H](COc....
33 2R6Y Ki = 0.32 nM LLC C27 H25 N O4 S c1cc(ccc1c....
34 4IU7 - 1GM C16 H13 F3 N2 O2 CCn1c(c2cc....
35 2POG Ki = 0.29 nM WST C18 H18 O3 c1cc(c2c(c....
36 5TNB - 7EB C28 H28 Br N O6 S CN(C)CCOc1....
37 1SJ0 ic50 = 0.8 nM E4D C27 H29 N O4 S c1cc(ccc1[....
38 5T92 ic50 = 16 nM 77W C25 H22 F N O3 C[C@]1(c2c....
39 3DT3 - 369 C23 H18 O4 Cc1cc2cc(c....
40 5AAU ic50 = 13.8 uM XBR C20 H19 Cl N2 O2 c1ccc2c(c1....
41 4IV2 - 1GR C18 H17 F3 N2 O2 CC(C)Cn1c2....
42 4IWC - 1GV C18 H16 O2 S Cc1cc(ccc1....
43 5FQP ic50 = 19 nM GQD C23 H27 N O3 C[C@@H]1Cc....
44 1YIN ic50 = 1.4 nM CM3 C29 H32 F N O4 C[C@@H]1c2....
45 4IVY - 1GT C18 H15 F3 N2 O2 C=CCCn1c2c....
46 2AYR Ki = 0.52 nM L4G C30 H31 N O5 S CS(=O)(=O)....
47 4IWF - 15Q C13 H9 Cl F N O3 c1cc(c(cc1....
48 5FQS ic50 = 44 nM J0W C23 H27 N O3 CC(C)CN1CC....
49 1QKT Kd = 0.92 nM EST C18 H24 O2 C[C@]12CC[....
50 5ACC ic50 = 0.676 nM KE9 C25 H25 F3 N2 O2 C[C@@H]1Cc....
51 1G5Y - REA C20 H28 O2 CC1=C(C(CC....
52 3PCU - LX8 C21 H24 O5 CC(=O)OC(C....
53 1FBY Kd = 1.5 nM REA C20 H28 O2 CC1=C(C(CC....
54 4N5G ic50 = 14.5 uM K09 C23 H23 F N4 CC1=C(c2cc....
55 2PJL ic50 = 190 nM 047 C23 H28 N2 Cc1ccc(cc1....
56 2JJ3 Kd = 0.281 uM JJ3 C20 H22 O4 COCc1cc(cc....
57 2Z4B Ki = 0.44 nM DC8 C18 H16 F2 O3 c1cc(ccc1[....
58 5TOA - EST C18 H24 O2 C[C@]12CC[....
59 1QKM - GEN C15 H10 O5 c1cc(ccc1C....
60 2GIU ic50 = 1.5 nM FBR C17 H19 Br O2 CCCC[C@@]1....
61 1QKN - RAL C28 H27 N O4 S c1cc(ccc1c....
62 1U9E ic50 = 5.7 nM 397 C14 H10 O3 c1cc(ccc1c....
63 1U3Q ic50 = 3.5 nM 272 C13 H9 N O4 c1cc2c(cc1....
64 2I0G Ki = 0.19 nM I0G C18 H18 O3 c1cc(ccc1[....
65 1HJ1 - PMB C6 H5 Hg O3 S c1cc(ccc1S....
66 2FSZ - OHT C26 H29 N O2 CC/C(=C(c1....
67 2NV7 ic50 = 5 nM 555 C17 H13 N O2 c1ccc2c(c1....
68 3FS1 - MYR C14 H28 O2 CCCCCCCCCC....
69 2ZAS ic50 = 13.9 nM 1OH C15 H16 O CC(C)(c1cc....
70 2EWP ic50 = 0.079 uM TXF C27 H31 N O3 CN(C)CCOc1....
71 1S9P - DES C18 H20 O2 CC/C(=C(/C....
72 2E2R Kd = 5.5 nM 2OH C15 H16 O2 CC(C)(c1cc....
73 2P7Z Kd = 0.262 uM OHT C26 H29 N O2 CC/C(=C(c1....
74 2GPU - OHT C26 H29 N O2 CC/C(=C(c1....
75 2P7A Kd = 0.788 uM 43M C7 H7 Cl O Cc1cc(ccc1....
76 2P7G Kd = 0.297 uM 2OH C15 H16 O2 CC(C)(c1cc....
77 1S9Q - OHT C26 H29 N O2 CC/C(=C(c1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 2OH; Similar ligands found: 5
No: Ligand ECFP6 Tc MDL keys Tc
1 2OH 1 1
2 1OH 0.724138 0.9
3 0CZ 0.466667 0.653846
4 27L 0.454545 0.666667
5 HQE 0.409091 0.65
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2E2R; Ligand: 2OH; Similar sites found: 511
This union binding pocket(no: 1) in the query (biounit: 2e2r.bio1) has 35 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1SS4 GSH 0.003442 0.50076 None
2 3B6C SDN 0.0008515 0.49848 None
3 1H8G CHT 0.004034 0.49092 None
4 1YC4 43P 0.001121 0.47536 None
5 3KMT SAH 0.0002589 0.46685 None
6 2ZSC BTN 0.0002896 0.46493 None
7 4LWU 20U 0.00164 0.46236 None
8 2FR6 URI 0.0004859 0.44172 None
9 4F4S EFO 0.009771 0.44147 None
10 1WGC SIA GAL BGC 0.02643 0.43561 None
11 1F5F DHT 0.0009702 0.43503 None
12 1ULE GLA GAL NAG 0.01809 0.43081 None
13 2JFV FLC 0.01098 0.42971 None
14 2CB8 MYA 0.02196 0.4266 None
15 2FR6 CTN 0.001298 0.42617 None
16 2VKL MLT 0.04787 0.42113 None
17 3RET PYR 0.01154 0.42088 None
18 1I36 NAP 0.0007738 0.41881 None
19 2O66 FLC 0.01521 0.41785 None
20 4KJU 1RH 0.0417 0.40819 None
21 1SS4 CIT 0.01848 0.40413 None
22 2IMF GSH 0.001768 0.40371 None
23 2IMF TOM 0.001768 0.40371 None
24 3RV5 DXC 0.005915 0.40018 None
25 2FEQ 34P 0.003754 0.41304 0.819672
26 1U7Z PMT 0.0001686 0.40427 0.884956
27 3AQT RCO 0.002702 0.47677 1.22951
28 1TMX HGX 0.006128 0.41676 1.22951
29 2HFN FMN 0.02029 0.40231 1.30719
30 3D3H M4O 0.005617 0.41021 1.5
31 3L1N PLM 0.03133 0.41404 1.54639
32 3S7O LBV 0.0001033 0.42154 1.63934
33 1RYI FAD 0.0001867 0.41645 1.63934
34 1RYI GOA 0.0002396 0.41343 1.63934
35 1MZV AMP 0.001882 0.4425 1.70213
36 1G8S MET 0.01457 0.42386 1.73913
37 9LDT OXM 0.0125 0.4537 2.04918
38 1EYE PMM 0.001136 0.44644 2.04918
39 1QS8 IVA VAL VAL STA ALA STA 0.0002372 0.43984 2.04918
40 3MAG 3MA 0.02376 0.43818 2.04918
41 3MAG SAH 0.00119 0.42357 2.04918
42 1A59 CIT 0.02701 0.41622 2.04918
43 3WXL ADP 0.02739 0.40989 2.04918
44 1WRA PC 0.03741 0.40919 2.04918
45 4DR9 BB2 0.02942 0.40084 2.08333
46 1S17 GNR 0.01059 0.41235 2.22222
47 1S8F GDP 0.005253 0.41528 2.25989
48 1FW1 GSH 0.003332 0.42309 2.31481
49 3AYS CT3 0.00125 0.44992 2.45902
50 2DWU DGL 0.002084 0.44587 2.45902
51 3MD0 GDP 0.002358 0.44357 2.45902
52 1A27 EST 0.001191 0.4361 2.45902
53 3W54 RNB 0.00398 0.43559 2.45902
54 2HFK E4H 0.005878 0.43147 2.45902
55 2NU8 COA 0.0001863 0.4278 2.45902
56 1EB9 HBA 0.00345 0.42687 2.45902
57 3NFZ 3NF 0.003479 0.42672 2.45902
58 3P7I P7I 0.008182 0.42509 2.45902
59 3V1V GST 0.001868 0.42439 2.45902
60 3HB5 E2B 0.0004237 0.42376 2.45902
61 2BP1 FLC 0.03108 0.41733 2.45902
62 2C7G FAD 0.0004212 0.41712 2.45902
63 3GJB AKG 0.01061 0.41544 2.45902
64 1H2B NAJ 0.00009511 0.41115 2.45902
65 2NXW TPP 0.0002054 0.41001 2.45902
66 2YP9 SIA CMO 0.006441 0.40606 2.45902
67 1QDS PGA 0.01547 0.40423 2.45902
68 1TDF FAD 0.0008772 0.40071 2.45902
69 3KFF ZBT 0.01917 0.42564 2.46914
70 4FFS BIG 0.0008718 0.4171 2.51046
71 3A2Y TS5 0.0001167 0.46942 2.53807
72 3E3U NVC 0.01366 0.41728 2.53807
73 1ECM TSA 0.0003402 0.47969 2.75229
74 2OFE NAG 0.003588 0.45274 2.8169
75 4QGE 35O 0.000003654 0.52981 2.86885
76 3LTW HLZ 0.002965 0.45667 2.86885
77 3BRE C2E 0.005202 0.44511 2.86885
78 3R9V DXC 0.01022 0.44408 2.86885
79 2QF7 COA 0.001304 0.43916 2.86885
80 1YHM AHD 0.005896 0.43675 2.86885
81 3JQ3 ADP 0.002777 0.43545 2.86885
82 4K10 NI9 0.01919 0.43018 2.86885
83 2YFT DQR 0.001813 0.42908 2.86885
84 1UXG FUM 0.00006279 0.42339 2.86885
85 1UXG NAD 0.00006279 0.42339 2.86885
86 4JZX 476 0.009786 0.42072 2.86885
87 1C7S CBS 0.005132 0.41987 2.86885
88 4OB6 S2T 0.003354 0.41882 2.86885
89 1E4E PHY 0.003621 0.41754 2.86885
90 4L7I SAM 0.003567 0.41388 2.86885
91 3MTW M3R 0.006047 0.40897 2.86885
92 1E4E ADP 0.003856 0.40892 2.86885
93 1M5B BN1 0.0008765 0.40866 2.86885
94 1JU4 BEZ 0.03785 0.40843 2.86885
95 2WTN FER 0.03697 0.40621 2.86885
96 2EJU SAH 0.004694 0.4058 2.86885
97 2PX6 DH9 0.02128 0.40448 2.86885
98 2BII MTV 0.002149 0.40413 2.86885
99 3W8S GSH 0.01453 0.41876 2.91262
100 3WUR O4B 0.006872 0.443 2.92398
101 2HNK SAH 0.002473 0.41226 2.92887
102 3EW2 BTN 0.001674 0.44996 2.96296
103 1POC GEL 0.0162 0.40694 2.98507
104 2ORV 4TA 0.0001352 0.43979 2.99145
105 2WOR 2AN 0.0003983 0.526 3
106 4F0E 0RU 0.02123 0.41533 3
107 4GO7 THR 0.008983 0.41413 3
108 3IBH GSH 0.0001287 0.4579 3.00429
109 4URN NOV 0.04744 0.40417 3.11111
110 4R29 SAM 0.0375 0.40225 3.125
111 1L3I SAH 0.001437 0.40039 3.125
112 2YLD CMO 0.04493 0.40848 3.14961
113 1EYQ NAR 0.0007291 0.46547 3.15315
114 3IX9 MTX 0.01335 0.4215 3.15789
115 2F2G HMH 0.03 0.41294 3.16742
116 4EKQ NPO 0.01994 0.41646 3.20856
117 2YIV YIV 0.0003131 0.52048 3.27869
118 1H16 PYR 0.001671 0.48353 3.27869
119 4COQ SAN 0.001084 0.47733 3.27869
120 2ZWS PLM 0.008154 0.47324 3.27869
121 1F1V DHY 0.0007358 0.4653 3.27869
122 2YIV NBN 0.002766 0.46492 3.27869
123 1KTC NGA 0.004602 0.43619 3.27869
124 3G58 988 0.008798 0.43475 3.27869
125 1V6A TRE 0.007257 0.43262 3.27869
126 1TZD ADP 0.0181 0.42811 3.27869
127 1F3L SAH 0.0006863 0.42421 3.27869
128 2Q8H TF4 0.02316 0.42381 3.27869
129 1R6D DAU 0.0002515 0.42094 3.27869
130 3IU9 T07 0.0004448 0.41811 3.27869
131 4MRP GSH 0.04684 0.41776 3.27869
132 3OTH CLJ 0.008184 0.41751 3.27869
133 1I0Z OXM 0.04433 0.41653 3.27869
134 3I8P 840 0.005038 0.41202 3.27869
135 1K6M AGS 0.00163 0.41149 3.27869
136 2AE2 NAP 0.0002155 0.41127 3.27869
137 2AE2 PTO 0.0002155 0.41127 3.27869
138 3N26 ARG 0.02811 0.40875 3.27869
139 1ZPD CIT 0.04776 0.40792 3.27869
140 1R6D NAD 0.0009179 0.40558 3.27869
141 3HYW DCQ 0.03838 0.40535 3.27869
142 1ID0 ANP 0.005718 0.43997 3.28947
143 1XE7 GUN 0.003181 0.47746 3.44828
144 1ZZ7 S0H 0.0006634 0.47348 3.53535
145 1Q3A NGH 0.02405 0.41615 3.63636
146 1XX4 BAM 0.0003611 0.52741 3.68852
147 3O2K QRP 0.0001716 0.48589 3.68852
148 1CZA ADP 0.003012 0.46884 3.68852
149 3LXI CAM 0.01235 0.43631 3.68852
150 2Q09 DI6 0.004592 0.43111 3.68852
151 4K7O EKZ 0.01766 0.42581 3.68852
152 1MLD CIT 0.01937 0.42539 3.68852
153 3ZQE DXC 0.02251 0.42342 3.68852
154 3SIX GDP 0.004231 0.42327 3.68852
155 4V3I ASP LEU THR ARG PRO 0.02778 0.42319 3.68852
156 1KYZ SAH 0.001703 0.42187 3.68852
157 1VDC FAD 0.0002993 0.41492 3.68852
158 3CEV ARG 0.01198 0.41316 3.68852
159 4KCF AKM 0.006453 0.40982 3.68852
160 1A05 IPM 0.0415 0.40768 3.68852
161 3O2K DST 0.02117 0.40668 3.68852
162 2C2A ADP 0.006127 0.40507 3.68852
163 4ETZ C2E 0.03935 0.40175 3.68852
164 2PTR 2SA 0.001319 0.40155 3.68852
165 1W3R PYR 0.005964 0.45542 3.7037
166 2WCI GSH 0.008213 0.43015 3.7037
167 3R51 MMA 0.01225 0.44641 3.75
168 4N7C AEF 0.01296 0.43198 3.97727
169 2B96 ANN 0.007747 0.41226 4.06504
170 4M5P 23W 0.0003166 0.52024 4.09836
171 3CHT 4NB 0.001995 0.47946 4.09836
172 1Y42 TYR 0.0006523 0.4738 4.09836
173 1CKM GTP 0.001411 0.45316 4.09836
174 1Q11 TYE 0.002387 0.44883 4.09836
175 1SQ5 PAU 0.002738 0.44619 4.09836
176 3U1T MLI 0.007369 0.44404 4.09836
177 1SQ5 ADP 0.00167 0.43965 4.09836
178 1XMY ROL 0.01375 0.42898 4.09836
179 1I2L DCS 0.0008986 0.4279 4.09836
180 4CCO OGA 0.007281 0.42734 4.09836
181 4J7H TRH 0.001119 0.42451 4.09836
182 1H65 GDP 0.001352 0.41784 4.09836
183 3V91 UPG 0.001741 0.41052 4.09836
184 2GWD GLU 0.01428 0.40986 4.09836
185 4IHQ ADP 0.01635 0.40732 4.09836
186 1XM4 PIL 0.02927 0.40428 4.09836
187 4M5P FMN 0.003422 0.40384 4.09836
188 1XMU ROF 0.02591 0.40357 4.09836
189 2W90 6PG 0.008054 0.40299 4.09836
190 4EXO PYR 0.03813 0.40661 4.10959
191 2Y7P SAL 0.003099 0.44381 4.12844
192 1ZS6 ADP 0.003306 0.43725 4.14201
193 1DBT U5P 0.003108 0.41234 4.1841
194 3GX0 GDS 0.004354 0.40352 4.18605
195 4PTZ FMN 0.005993 0.40543 4.18848
196 3KJQ B94 0.001697 0.43937 4.21053
197 4IAE 1DX 0.0004391 0.41441 4.2328
198 1LSS NAD 0.002109 0.41113 4.28571
199 3N7S 3N7 0.007775 0.45109 4.34783
200 3F81 STT 0.001642 0.48392 4.37158
201 1TUV VK3 0.006342 0.46159 4.38596
202 1YOA FMN 0.0007467 0.53322 4.40252
203 3TL1 JRO 0.03811 0.40939 4.40252
204 1YOA FAD 0.002791 0.40357 4.40252
205 2Q37 3AL 0.002396 0.45467 4.41989
206 2QCX PF1 0.0005576 0.48363 4.5082
207 4JWX 1N4 0.0006836 0.4729 4.5082
208 4LHM AZZ 0.001714 0.46133 4.5082
209 2YVF FAD 0.0001992 0.43005 4.5082
210 4IMG NGF 0.0009061 0.42777 4.5082
211 1W2D ADP 0.02488 0.41149 4.5082
212 2JC9 ADN 0.0422 0.40696 4.5082
213 4P4T GDP 0.005629 0.40292 4.5082
214 1EWF PC1 0.0006502 0.40287 4.5082
215 3B1J NAD 0.0006495 0.40183 4.5082
216 4OYA 1VE 0.0073 0.40065 4.5082
217 4JP3 CIT 0.002666 0.43141 4.60251
218 4IBF 1D5 0.009559 0.42489 4.65116
219 1VE3 SAM 0.001563 0.42322 4.84582
220 2W3L DRO 0.003706 0.47395 4.86111
221 4B9E FAH 0.0002909 0.51282 4.91803
222 1DXY COI 0.0008072 0.50895 4.91803
223 4M51 BEZ 0.001189 0.49104 4.91803
224 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 0.002641 0.48256 4.91803
225 1RZM E4P 0.00198 0.47204 4.91803
226 2WA4 069 0.0003563 0.46686 4.91803
227 3P3N AKG 0.002282 0.46204 4.91803
228 4KCT PYR 0.001263 0.45522 4.91803
229 4JEJ 1GP 0.0009502 0.44959 4.91803
230 1UOU CMU 0.0009181 0.44518 4.91803
231 3A1I UNU 0.001775 0.44356 4.91803
232 2Y7G AAE 0.001003 0.43895 4.91803
233 1GPM AMP 0.01013 0.4299 4.91803
234 3LLI FAD 0.001496 0.42736 4.91803
235 4DYO SD4 0.007397 0.4222 4.91803
236 3EE4 MYR 0.005351 0.41937 4.91803
237 1AUA BOG 0.02635 0.41814 4.91803
238 1RZM PEP 0.01683 0.41113 4.91803
239 1HK8 DGT 0.00499 0.40841 4.91803
240 3BJC WAN 0.0471 0.40434 4.91803
241 4GYW UDP 0.0002074 0.40208 4.91803
242 3IA4 MTX 0.004539 0.44074 4.93827
243 3KO0 TFP 0.01487 0.42704 4.9505
244 1MXI SAH 0.0006622 0.43682 5
245 1UW1 ADP 0.0188 0.41361 5
246 3S9K CIT 0.009501 0.46192 5.08475
247 2ZL4 ALA ALA ALA ALA 0.04018 0.40813 5.10204
248 3PMD 11A 0.00006892 0.50241 5.22876
249 1YKD CMP 0.003622 0.43751 5.27638
250 3BHO B4P 0.02595 0.43605 5.28846
251 1GJW GLC 0.0009977 0.48662 5.32787
252 4L1F COS 0.00002049 0.47096 5.32787
253 3B99 U51 0.00555 0.44062 5.32787
254 4E13 NAD 0.0008078 0.4256 5.32787
255 1WDA BAG 0.007748 0.42133 5.32787
256 2CFU 1DB 0.001402 0.41729 5.32787
257 1HDR NAD 0.0002757 0.41692 5.32787
258 1GJW MAL 0.00781 0.41668 5.32787
259 3PJU C2E 0.00001598 0.41615 5.32787
260 4Q86 AMP 0.01783 0.41158 5.32787
261 4LH7 NMN 0.04197 0.4082 5.32787
262 1TFZ 869 0.003393 0.40737 5.32787
263 1I2B NAD 0.0009963 0.40539 5.32787
264 1I2B UPG 0.0009963 0.40539 5.32787
265 1I2B USQ 0.0009963 0.40539 5.32787
266 1MOQ GLP 0.005139 0.40436 5.32787
267 3NV6 CAM 0.02686 0.40118 5.32787
268 2JBH 5GP 0.0154 0.40844 5.33333
269 1QD0 RR6 0.01092 0.40653 5.46875
270 1SJW NGV 0.000374 0.4554 5.55556
271 4QC6 30N 0.008102 0.40844 5.58659
272 3SJ0 DXC 0.007412 0.44392 5.6338
273 1SC3 MLI 0.001594 0.48458 5.68182
274 1EJE FMN 0.002445 0.41614 5.72917
275 1O9U ADZ 0.001235 0.49919 5.7377
276 4WBD ADP 0.00338 0.46065 5.7377
277 4DS8 A8S 0.004074 0.44304 5.7377
278 2ZJF BSU 0.001948 0.44188 5.7377
279 4WBD CIT 0.01203 0.43988 5.7377
280 4NAO AKG 0.01084 0.43581 5.7377
281 1WNG SAH 0.0005587 0.43524 5.7377
282 1E5F PLP 0.001993 0.4275 5.7377
283 1T26 GBD 0.001611 0.41969 5.7377
284 1T26 NAI 0.001611 0.41969 5.7377
285 3DGB MUC 0.006562 0.41553 5.7377
286 3HAZ FAD 0.0001854 0.41435 5.7377
287 4KOA NDP 0.004192 0.41125 5.7377
288 4EIL FOL 0.0163 0.41006 5.7377
289 2B7N NTM 0.03054 0.40386 5.7377
290 2WPW ACO 0.02399 0.40196 5.7377
291 2WPX ACO 0.02174 0.4009 5.7377
292 4NB5 2JT 0.006857 0.42105 5.84795
293 2WT9 NIO 0.0489 0.40418 5.95745
294 1Y1A GSH 0.0001385 0.57975 6.01093
295 1GU3 BGC BGC BGC BGC BGC 0.006123 0.43068 6.04027
296 2Z9V PXM 0.0008199 0.4694 6.14754
297 2IZ1 ATR 0.002325 0.46167 6.14754
298 2EB5 OXL 0.002445 0.46063 6.14754
299 3TFC PEP 0.002575 0.44738 6.14754
300 3QV9 QV7 0.009219 0.42785 6.14754
301 1SJD NPG 0.001693 0.40432 6.14754
302 3HR1 PF9 0.01305 0.40222 6.14754
303 1KYQ NAD 0.006701 0.40015 6.14754
304 4M7F BM3 0.02859 0.40083 6.19469
305 1ZJ6 G3D 0.002015 0.43635 6.41711
306 1V7R CIT 0.0237 0.43825 6.45161
307 1B4P GPS 0.00337 0.41105 6.45161
308 1SBR VIB 0.002073 0.47772 6.5
309 3TKA CTN 0.008071 0.47965 6.55738
310 1I0B PEL 0.004604 0.47045 6.55738
311 2PP3 LGT 0.0003907 0.45981 6.55738
312 1A8S PPI 0.0008271 0.45467 6.55738
313 3GTD MLI 0.004048 0.44424 6.55738
314 3DG6 MUC 0.001354 0.43852 6.55738
315 3B9Z CO2 0.01876 0.42547 6.55738
316 1J78 VDY 0.01628 0.4251 6.55738
317 3TKA SAM 0.0009122 0.42377 6.55738
318 1J78 OLA 0.02966 0.41422 6.55738
319 3Q2H QHF 0.01286 0.40846 6.55738
320 1BTN I3P 0.002155 0.50808 6.60377
321 2FP2 TSA 0.008166 0.41755 6.62651
322 2FOI JPA 0.001488 0.44676 6.66667
323 4EJ1 FOL 0.007444 0.42642 6.71642
324 1JR8 FAD 0.005731 0.41497 6.83761
325 3GKJ HC3 0.01097 0.40854 6.89655
326 3GM5 CIT 0.03563 0.40529 6.91824
327 3O01 DXC 0.0001555 0.57216 6.96721
328 2JHP GUN 0.004112 0.45689 6.96721
329 1PX8 XYP 0.002707 0.45224 6.96721
330 3SHR CMP 0.001334 0.44873 6.96721
331 3Q9T FAY 0.00007448 0.42137 6.96721
332 1OAA OAA 0.0001733 0.41736 6.96721
333 3GQT UFO 0.01954 0.41316 6.96721
334 3V1S 0LH 0.04493 0.4049 6.96721
335 2BOI MFU 0.008009 0.4255 7.07965
336 2BZ1 TAU 0.003804 0.49239 7.14286
337 1W7J ADP BEF 0.003529 0.41405 7.28477
338 3TDC 0EU 0.0001606 0.58349 7.37705
339 1Z44 NPO 0.01089 0.46595 7.37705
340 2NCD ADP 0.003151 0.44922 7.37705
341 3QCP FAD 0.001055 0.43661 7.37705
342 3CQ5 PMP 0.004965 0.42965 7.37705
343 1Z41 FMN 0.002443 0.42411 7.37705
344 1Z44 FMN 0.003152 0.42404 7.37705
345 3I51 45C 0.004321 0.4229 7.37705
346 3T58 FAD 0.003502 0.40718 7.37705
347 2Q28 ADP 0.003992 0.40486 7.37705
348 4LWA Q13 0.0003777 0.40341 7.37705
349 2NVK NAP 0.02699 0.40195 7.37705
350 3CH5 GDP 0.01186 0.40506 7.40741
351 3HP9 CF1 0.007996 0.45725 7.46888
352 3G4Q MCH 0.01859 0.41425 7.53425
353 1OGD RIP 0.006895 0.42839 7.63359
354 4JHG ZEA 0.006186 0.40859 7.7381
355 1Y2W NAG 0.001561 0.46985 7.74648
356 2BD0 BIO 0.01736 0.4346 7.78689
357 2QJY UQ2 0.01571 0.43033 7.78689
358 2RKN LP3 0.02928 0.40093 7.79221
359 3ZPG 5GP 0.001709 0.49172 7.8534
360 2VAR AMP 0.000577 0.46392 8.19672
361 4WVH ASP HIS ASP ALA HIS ALA 0.001559 0.4513 8.19672
362 2VAR KDF 0.0009774 0.44909 8.19672
363 3I0O ADP 0.001867 0.44265 8.19672
364 3I0O SMI 0.005112 0.4396 8.19672
365 1U5R ATP 0.002099 0.42664 8.19672
366 3RLF MAL 0.01686 0.42431 8.19672
367 2VAR KDG 0.005082 0.42004 8.19672
368 3DER ALA LYS 0.001361 0.41773 8.19672
369 1XI9 PLP 0.03332 0.40862 8.19672
370 1NF8 BOG 0.00118 0.49915 8.21256
371 2F59 INI 0.005701 0.40271 8.28025
372 2QLX RM4 0.01034 0.43682 8.33333
373 1G27 BB1 0.01526 0.40503 8.33333
374 3BY8 MLT 0.004373 0.45517 8.4507
375 1Y7P RIP 0.007445 0.45051 8.52018
376 2Z6C FMN 0.01498 0.4054 8.52713
377 4C6F NCD 0.0005728 0.46406 8.60656
378 4C6F DOR 0.0005728 0.46406 8.60656
379 4I90 CHT 0.03425 0.4111 8.60656
380 4CCW VKC 0.02975 0.41005 8.60656
381 5RHN 8BR 0.001881 0.42847 8.69565
382 3OGN 3OG 0.005409 0.42934 8.87097
383 2BO4 FLC 0.003754 0.45842 9.01639
384 1B5E DCM 0.001157 0.45685 9.01639
385 2PR5 FMN 0.0005575 0.43955 9.09091
386 4HBM 0Y7 0.02531 0.41111 9.16667
387 2E1A MSE 0.003088 0.43853 9.33333
388 4E28 9MZ 0.001283 0.47387 9.42623
389 4E28 0MZ 0.001922 0.45905 9.42623
390 2R5T ANP 0.0003674 0.43747 9.42623
391 3ZEI AWH 0.0005543 0.40683 9.42623
392 1RL4 BL5 0.007916 0.44577 9.57447
393 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 0.0006391 0.5138 9.62343
394 4U9W COA 0.001591 0.42699 9.66184
395 4U9W SER GLY ARG GLY LYS NH2 0.03273 0.40471 9.66184
396 4RJK PYR 0.000143 0.53777 9.83607
397 3D2Y AH0 ALA FGA LYS 0.0003528 0.44679 9.83607
398 4C2G ALA ALA ALA ALA 0.004218 0.4327 9.83607
399 2F2U M77 0.008948 0.4142 9.83607
400 2BYC FMN 0.01988 0.40925 10.219
401 1T0S BML 0.001652 0.48378 10.2459
402 2Z9I GLY ALA THR VAL 0.008195 0.45149 10.2459
403 1RHC F42 ACN 0.0003442 0.4098 10.2459
404 2RHQ GAX 0.003333 0.40096 10.2459
405 2P8O BVA 0.002903 0.41723 10.3093
406 3RF4 FUN 0.003348 0.44232 10.3448
407 2YCD GTB 0.002299 0.43402 10.4348
408 2YDW WSH 0.0005022 0.46644 10.4575
409 2WDQ CBE 0.03726 0.41169 10.5042
410 4L77 CNL 0.01262 0.43546 10.6557
411 4M37 SAH 0.00107 0.42521 10.6557
412 1XVA SAM 0.002221 0.41392 10.6557
413 2YB9 HA0 0.0003774 0.40864 10.6557
414 4ASJ N6A 0.002805 0.4003 10.6557
415 4DN8 BMA 0.00179 0.46703 10.8974
416 1UF5 CDT 0.002103 0.44049 11.0656
417 1XVB 3BR 0.006814 0.44045 11.0656
418 3AB4 THR 0.03122 0.40638 11.0656
419 1KBI FMN 0.001036 0.40479 11.0656
420 1KBI PYR 0.001036 0.40479 11.0656
421 2WK1 SAH 0.004305 0.40037 11.0656
422 4K30 NLG 0.009223 0.42278 11.25
423 4OAS 2SW 0.001484 0.46448 11.4583
424 1BUC CAA 0.00003848 0.45743 11.4754
425 2WMO GTP 0.001939 0.43237 11.4754
426 3RK0 AMP 0.002246 0.43443 11.8143
427 4JCA CIT 0.01072 0.45739 11.8852
428 2GN2 C5P 0.01182 0.44262 11.8852
429 2VDJ HSE 0.03117 0.41866 11.8852
430 3NJQ NJQ 0.01275 0.43523 11.9171
431 2Y6P CTP 0.01147 0.40969 11.9658
432 3BRN SRO 0.03018 0.41585 12.1019
433 2GBB CIT 0.01854 0.42212 12.1795
434 3F3E LEU 0.00003397 0.42925 12.2951
435 3UEC ALA ARG TPO LYS 0.005421 0.45059 12.3288
436 3QDY CBS 0.001874 0.47321 13.2867
437 3QDT A2G GAL 0.004113 0.46363 13.2867
438 3QDY A2G GAL 0.004155 0.46341 13.2867
439 3CF6 SP1 0.001054 0.43813 13.7725
440 2UYN 2KT 0.04398 0.40277 13.9535
441 4IA6 EIC 0.003756 0.47181 14.3443
442 2XDQ MGX 0.005 0.46706 14.3443
443 1QZZ SAM 0.0003027 0.46417 14.7541
444 3VCA PRO 0.009759 0.42415 14.7541
445 1MFI FHC 0.02553 0.41564 14.9123
446 1NVV GNP 0.0009597 0.40899 15.0602
447 2HHP FLC 0.004577 0.48586 15.1639
448 1Y75 NAG 0.0004317 0.47525 15.2542
449 1Q6O LG6 0.001841 0.42882 15.2778
450 3JRS A8S 0.01047 0.41932 15.3846
451 1TH8 ADP 0.005018 0.42472 15.5172
452 2FYU FDN 0.0006999 0.43595 15.5738
453 3KDJ A8S 0.00806 0.41782 15.8416
454 1TW4 CHD 0.0333 0.40144 16
455 4I67 G G G RPC 0.01123 0.42931 16.092
456 1C1L GAL BGC 0.003158 0.4621 16.7883
457 1TV5 N8E 0.003645 0.46454 17.623
458 1TV5 ORO 0.005814 0.40775 17.623
459 1JQ5 NAD 0.01281 0.40124 18.4426
460 2V5E SCR 0.0236 0.41145 18.8119
461 3ZCB ATP 0.01069 0.4225 19.1919
462 4DOL PLM 0.008614 0.41985 19.3548
463 2C5S AMP 0.001702 0.44965 20.9016
464 2VWA PTY 0.009892 0.45212 21.7822
465 3EYK EYK 0.01302 0.45205 22.093
466 1OYB FMN 0.0005032 0.42499 22.1311
467 1OYB HBA 0.000482 0.41505 22.1311
468 2ZJ5 ADP 0.003966 0.44465 23.7705
469 4BG1 IVL 0.001635 0.41497 24.1803
470 4BG1 OGA 0.001635 0.41497 24.1803
471 3V49 PK0 0.00000006128 0.61664 31.1475
472 2AX9 BHM 0.0000000003104 0.60667 31.1475
473 2A3I C0R 0.00000000001563 0.79575 31.9672
474 5HCV 60R 0.0001106 0.53337 31.9672
475 4UDB CV7 0.00008311 0.52143 32.377
476 2O4J VD4 0.00007521 0.47969 32.377
477 3SP6 IL2 0.000564 0.47086 34.0164
478 1K7L 544 0.003246 0.41659 34.0164
479 3KDU NKS 0.002671 0.40312 34.0164
480 1M2Z DEX 0.0000000004894 0.73909 34.4262
481 1NHZ 486 0.00000002818 0.64473 34.4262
482 1M2Z BOG 0.001104 0.52047 34.4262
483 3BQD DAY 0.00000003572 0.5085 34.4262
484 3RY9 1CA 0.0000000001288 0.78614 34.8361
485 4LSJ LSJ 0.00000000004322 0.58854 34.8361
486 2Q1H AS4 0.00000000003299 0.56959 35.2459
487 2PRG BRL 0.0001982 0.4966 35.2459
488 2HFP NSI 0.0002321 0.47123 35.2459
489 4OAR 2S0 0.0000000007971 0.72956 35.6557
490 1SR7 MOF 0.00000000002814 0.66681 35.6557
491 3GN8 DEX 0.0000000004227 0.74195 36.0656
492 5UFS 1TA 0.0002567 0.50691 36.0656
493 3BEJ MUF 0.00001975 0.43218 36.1345
494 3ET1 ET1 0.001518 0.4552 37.5
495 3RUU 37G 0.00003638 0.48837 37.5546
496 1N46 PFA 0.0005707 0.44757 37.7049
497 3DCT 064 0.00002859 0.50528 38.0952
498 3L0E G58 0.00005818 0.48419 38.5246
499 3KFC 61X 0.00008132 0.46057 39.3443
500 2NPA MMB 0.00671 0.41502 40
501 4DM8 REA 0.00003317 0.51184 40.1639
502 3IPQ 965 0.00008066 0.46746 40.1639
503 3KMZ EQO 0.000005657 0.52497 40.5738
504 3JZB 4HY 0.0001455 0.46452 40.9836
505 4Q0A 4OA 0.0007764 0.46449 42.623
506 4Q0A GLY HIS LYS ILE LEU HIS ARG LEU LEU GLN 0.0008571 0.43274 42.623
507 4P6X HCY 0.0000000008861 0.54305 42.8571
508 5G5W R8C 0.001503 0.45774 42.8571
509 2R40 EPH 0.0003755 0.44821 44.6721
510 2R40 20E 0.0007371 0.44639 44.6721
511 3KMR EQN 0.00001963 0.53773 46.1538
512 4E2J MOF 0.0000000005323 0.71931 50
513 4P6W MOF 0.000000002752 0.68844 50
514 4DK7 0KS 0.0001069 0.50398 50
515 3OKI OKI 0.004326 0.42677 50
Feedback