-->
Receptor
PDB id Resolution Class Description Source Keywords
2DRZ 2.19 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THE EARTHWORM LECTIN C-TERMINAL DOMAIN MUTANT IN COMPLEX WITH LACTOSE LUMBRICUS TERRESTRIS EARTHWORM LUMBRICUS TERRESTRIS SIALIC ACID GALACTOSE IN VITRO EVOLUTION BETA-TREFOIL FOLD SUGAR COMPLEX SUGAR BINDING PROTEIN
Ref.: TAILORING A NOVEL SIALIC ACID-BINDING LECTIN FROM A RICIN-B CHAIN-LIKE GALACTOSE-BINDING PROTEIN BY NATURAL EVOLUTION-MIMICRY J.BIOCHEM. V. 141 389 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BGC GAL A:270;
B:272;
Valid;
Valid;
none;
none;
submit data
342.297 n/a O(C1C...
SO4 A:1001;
A:1002;
A:1003;
B:1004;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2ZQO 1.8 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THE EARTHWORM R-TYPE LECTIN C-HALF IN COMPLEX WITH GALNAC LUMBRICUS TERRESTRIS EARTHWORM LUMBRICUS TERRESTRIS HEMAGGLUTININ R-TYPE LECTIN BETA-TREFOIL FOLD SUGAR COMPLEX LECTIN SUGAR BINDING PROTEIN
Ref.: SUGAR-COMPLEX STRUCTURES OF THE C-HALF DOMAIN OF THE GALACTOSE-BINDING LECTIN EW29 FROM THE EARTHWORM LUMBRICUS TERRESTRIS ACTA CRYSTALLOGR.,SECT.D V. 65 49 2009
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 2ZQN - BGC GAL n/a n/a
2 2DS0 - SIA GAL BGC n/a n/a
3 2DRZ - BGC GAL n/a n/a
4 2ZQO - NGA C8 H15 N O6 CC(=O)N[C@....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 2ZQN - BGC GAL n/a n/a
2 2DS0 - SIA GAL BGC n/a n/a
3 2DRZ - BGC GAL n/a n/a
4 2ZQO - NGA C8 H15 N O6 CC(=O)N[C@....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 2ZQN - BGC GAL n/a n/a
2 2DS0 - SIA GAL BGC n/a n/a
3 2DRZ - BGC GAL n/a n/a
4 2ZQO - NGA C8 H15 N O6 CC(=O)N[C@....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: BGC GAL; Similar ligands found: 333
No: Ligand ECFP6 Tc MDL keys Tc
1 GLA GLA 1 1
2 GAL BGC 1 1
3 GLC GAL 1 1
4 BMA GAL 1 1
5 LBT 1 1
6 BGC GAL 1 1
7 CBI 1 1
8 MAL 1 1
9 CBK 1 1
10 BGC BMA 1 1
11 N9S 1 1
12 MAB 1 1
13 LAT 1 1
14 GLA GAL 1 1
15 B2G 1 1
16 BMA BMA BMA 0.909091 1
17 GLA GAL GLC 0.909091 1
18 GLC BGC BGC 0.909091 1
19 GLC BGC BGC BGC 0.909091 1
20 GLC GLC GLC GLC GLC 0.909091 1
21 CT3 0.909091 1
22 BGC GLC GLC GLC 0.909091 1
23 BGC BGC BGC BGC 0.909091 1
24 CTT 0.909091 1
25 CTR 0.909091 1
26 GLC GAL GAL 0.909091 1
27 MAN BMA BMA BMA BMA BMA 0.909091 1
28 BGC BGC BGC GLC 0.909091 1
29 CEY 0.909091 1
30 B4G 0.909091 1
31 BGC BGC BGC 0.909091 1
32 GLC GLC BGC 0.909091 1
33 CE5 0.909091 1
34 BGC BGC BGC BGC BGC BGC 0.909091 1
35 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.909091 1
36 BMA BMA BMA BMA BMA BMA 0.909091 1
37 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.909091 1
38 GLA GAL BGC 0.909091 1
39 MLR 0.909091 1
40 MAN BMA BMA 0.909091 1
41 BGC GLC GLC GLC GLC GLC GLC 0.909091 1
42 BMA BMA BMA BMA BMA 0.909091 1
43 BGC BGC GLC 0.909091 1
44 MAN MAN BMA BMA BMA BMA 0.909091 1
45 BGC GLC GLC 0.909091 1
46 BGC BGC BGC BGC BGC 0.909091 1
47 MT7 0.909091 1
48 GLC BGC BGC BGC BGC 0.909091 1
49 CE6 0.909091 1
50 MTT 0.909091 1
51 CE8 0.909091 1
52 MAN BMA BMA BMA BMA 0.909091 1
53 GLC BGC GLC 0.909091 1
54 DXI 0.909091 1
55 GLC BGC BGC BGC BGC BGC 0.909091 1
56 CEX 0.909091 1
57 GAL GAL GAL 0.909091 1
58 BMA MAN BMA 0.909091 1
59 BGC GLC GLC GLC GLC 0.909091 1
60 GLA GAL GAL 0.816327 1
61 BGC BGC BGC BGC BGC BGC BGC BGC 0.754717 1
62 BMA BMA GLA BMA BMA 0.689655 1
63 XYT 0.685185 0.767442
64 LAT GLA 0.680851 1
65 GLC GLC GLC BGC 0.672414 1
66 U63 0.647059 0.891892
67 MMA MAN 0.64 0.942857
68 DR5 0.64 0.942857
69 GLA EGA 0.634615 0.942857
70 GAL FUC 0.615385 0.941176
71 2M4 0.612245 1
72 BGC GAL FUC 0.610169 0.970588
73 FUC GAL GLC 0.610169 0.970588
74 8B7 0.610169 0.970588
75 GLC GAL FUC 0.610169 0.970588
76 LAT FUC 0.610169 0.970588
77 BGC GLA GAL FUC 0.609375 0.970588
78 BQZ 0.608696 0.909091
79 BGC GAL NAG GAL 0.606061 0.733333
80 GAL NAG GAL GLC 0.606061 0.733333
81 BMA BMA BMA BMA 0.603448 0.941176
82 M3M 0.6 1
83 LB2 0.6 1
84 NGR 0.6 1
85 MAN GLC 0.6 1
86 MAL EDO 0.592593 0.942857
87 BGC BGC BGC XYS GAL 0.588235 0.942857
88 XYS BGC BGC BGC BGC XYS BGC BGC BGC 0.588235 0.942857
89 XYS BGC BGC XYS BGC XYS BGC BGC BGC 0.588235 0.942857
90 BGC BGC BGC XYS BGC BGC 0.588235 0.942857
91 LAT NAG GAL 0.588235 0.733333
92 GLC GAL NAG GAL 0.588235 0.733333
93 NGA GAL BGC 0.587302 0.733333
94 TRE 0.581395 1
95 ABD 0.57971 0.75
96 NLC 0.578947 0.733333
97 NDG GAL 0.578947 0.733333
98 GAL NDG 0.578947 0.733333
99 5GO 0.578947 0.66
100 DEL 0.574074 0.970588
101 MVP 0.571429 0.733333
102 GAL NGA GLA BGC GAL 0.571429 0.733333
103 GAL BGC BGC XYS 0.569231 0.942857
104 SGA BGC 0.568965 0.66
105 BGC BGC 0.566038 0.914286
106 BMA BMA 0.566038 0.914286
107 GLC GLC XYP 0.557377 1
108 BGC BGC XYS BGC 0.552239 0.942857
109 NAG GAL BGC 0.552239 0.733333
110 GLA GAL BGC 5VQ 0.551724 0.891892
111 G2F BGC BGC BGC BGC BGC 0.55 0.868421
112 GLA MBG 0.54902 0.942857
113 GLC ACI G6D BGC 0.547945 0.733333
114 GLC G6D ACI GLC 0.547945 0.733333
115 GLC ACI GLD GLC 0.547945 0.733333
116 GLC G6D ADH GLC 0.547945 0.733333
117 GLC BGC BGC BGC BGC BGC BGC 0.545455 1
118 BGC BGC BGC GLC BGC BGC 0.545455 1
119 BMA BMA MAN 0.535714 1
120 MAN MAN BMA 0.535714 1
121 NGA GLA GAL BGC 0.535211 0.733333
122 GAL BGC BGC BGC XYS BGC XYS 0.533333 0.942857
123 BGC BGC BGC XYS BGC XYS GAL 0.533333 0.942857
124 BGC BGC BGC XYS BGC XYS XYS 0.528571 0.942857
125 BGC BGC XYS BGC XYS BGC XYS 0.528571 0.942857
126 GLC BGC BGC XYS BGC XYS XYS 0.528571 0.942857
127 BMA MAN MAN MAN 0.525424 1
128 GLA GAL GLC NBU 0.52459 0.846154
129 FUC BGC GAL 0.52459 0.970588
130 GLC GLC G6D ACI GLC GLC GLC 0.519481 0.733333
131 GLC ACI GLD GAL 0.519481 0.702128
132 GLC ACI G6D GLC 0.519481 0.702128
133 BGC BGC BGC FRU 0.516129 0.868421
134 DOM 0.509091 0.942857
135 G3I 0.507937 0.767442
136 LMU 0.507937 0.785714
137 DMU 0.507937 0.785714
138 UMQ 0.507937 0.785714
139 OXZ BGC BGC 0.507937 0.6875
140 G2I 0.507937 0.767442
141 LMT 0.507937 0.785714
142 GAL XYS XYS BGC BGC BGC XYS GAL BGC 0.506329 0.942857
143 BGC BGC XYS BGC GAL XYS BGC XYS GAL 0.506329 0.942857
144 GAL BGC BGC BGC XYS XYS 0.506329 0.942857
145 GLC BGC BGC XYS BGC XYS XYS GAL GAL 0.506329 0.942857
146 GLC BGC BGC XYS BGC XYS XYS GAL 0.506329 0.942857
147 FMO 0.5 0.868421
148 MAN BMA NAG 0.5 0.733333
149 SOR GLC GLC 0.5 0.970588
150 GLA GAL NAG 0.5 0.733333
151 8VZ 0.5 0.673469
152 ACR GLC GLC GLC 0.493827 0.702128
153 GLC GLC DAF BGC 0.493827 0.702128
154 GLC GLC ACI G6D GLC GLC 0.493827 0.702128
155 ARE 0.493827 0.733333
156 GLC GLC AGL HMC GLC 0.493827 0.702128
157 AAO 0.493827 0.733333
158 GLC GLC XYS 0.492308 0.970588
159 MAN BMA MAN 0.491803 1
160 CGC 0.491525 0.941176
161 5QP 0.491228 0.885714
162 GAL MBG 0.490909 0.942857
163 MDM 0.490909 0.942857
164 RZM 0.490909 0.688889
165 M13 0.490909 0.942857
166 GAL NAG MAN 0.485294 0.733333
167 SOR GLC GLC GLC 0.484848 0.970588
168 GLO GLC GLC GLC 0.484848 0.970588
169 6UZ 0.484848 0.846154
170 LAG 0.484848 0.6
171 GAL BGC NAG GAL 0.478873 0.733333
172 GTM BGC BGC 0.477612 0.868421
173 10M 0.477612 0.733333
174 MAN MAN MAN MAN 0.476923 1
175 MAN MAN BMA MAN 0.476923 1
176 GLA GAL NAG FUC GAL GLC 0.47619 0.717391
177 GAL GAL SO4 0.47619 0.66
178 NAG BMA 0.47619 0.653061
179 GAL NGA 0.47541 0.733333
180 A2G GAL 0.47541 0.733333
181 GAL A2G 0.47541 0.733333
182 GLA BMA 0.472727 1
183 GLC BGC 0.472727 1
184 GAL GAL 0.472727 1
185 GLA GLC 0.472727 1
186 BGC GLA 0.472727 1
187 GAL GLC 0.472727 1
188 GLA BGC 0.472727 1
189 BMA GLA 0.472727 1
190 BMA MAN 0.472727 1
191 MAN MAN 0.472727 1
192 BGC GLC 0.472727 1
193 MLB 0.472727 1
194 GLC GLC 0.472727 1
195 MAN BMA 0.472727 1
196 LAK 0.472727 1
197 NPJ 0.470588 0.622642
198 FUC GAL NAG GAL BGC 0.469136 0.717391
199 GAL GLC NAG GAL FUC 0.469136 0.717391
200 GLC NAG GAL GAL FUC 0.469136 0.717391
201 MAN MAN MAN GLC 0.46875 1
202 ABL 0.466667 0.702128
203 FRU GAL 0.465517 0.842105
204 BMA FRU 0.465517 0.842105
205 DAF BGC 0.464789 0.733333
206 DAF GLC 0.464789 0.733333
207 TM6 0.463768 0.916667
208 BGC SGC BGC SGC BGC SGC BGC SGC 0.463768 0.916667
209 LSE 0.462687 0.6875
210 FUC GLA GLA 0.460317 0.970588
211 GAL GAL FUC 0.460317 0.970588
212 FUC GAL GLA 0.460317 0.970588
213 GLA GLA FUC 0.460317 0.970588
214 GLA GAL FUC 0.460317 0.970588
215 IFM BMA 0.457627 0.711111
216 9MR 0.457627 0.744186
217 IFM BGC 0.457627 0.711111
218 BMA IFM 0.457627 0.711111
219 BGC OXZ 0.457627 0.666667
220 RCB 0.457143 0.622642
221 GLO GLC GLC 0.457143 0.942857
222 MAN MAN MAN 0.45614 1
223 GLC GLC GLC GLC BGC 0.45614 1
224 GLC GLC GLC GLC GLC BGC 0.45614 1
225 BMA MAN MAN 0.45614 1
226 GLC GLC GLC 0.45614 1
227 WOO 0.454545 0.848485
228 GIV 0.454545 0.848485
229 BGC 0.454545 0.848485
230 ALL 0.454545 0.848485
231 GAL 0.454545 0.848485
232 GLA 0.454545 0.848485
233 GLC 0.454545 0.848485
234 GXL 0.454545 0.848485
235 BMA 0.454545 0.848485
236 MAN 0.454545 0.848485
237 ACI GLD GLC GAL 0.453333 0.733333
238 DAF BGC GLC 0.453333 0.733333
239 DAF GLC GLC 0.453333 0.733333
240 MGL SGC BGC BGC 0.450704 0.868421
241 MGL SGC GLC GLC 0.450704 0.868421
242 CM5 0.450704 0.891892
243 MAN MAN MAN BMA MAN 0.450704 1
244 BGC BGC SGC MGL 0.450704 0.868421
245 MAN MNM 0.45 0.702128
246 GLC DMJ 0.45 0.695652
247 A2G GAL BGC FUC 0.45 0.717391
248 NOJ GLC 0.45 0.695652
249 NOY BGC 0.45 0.702128
250 BMA MAN MAN MAN MAN 0.449275 1
251 GCS GCS 0.448276 0.767442
252 PA1 GCS 0.448276 0.767442
253 M5S 0.447761 1
254 MAN BMA MAN MAN MAN 0.447761 1
255 TXT 0.447368 0.767442
256 GAC 0.447368 0.767442
257 GLC GAL NAG GAL FUC FUC 0.447059 0.702128
258 BGC GAL NAG GAL FUC FUC 0.447059 0.702128
259 GAL NAG GAL NAG GAL NAG 0.445946 0.673469
260 NAG GAL GAL NAG GAL 0.445946 0.6875
261 NAG GAL GAL NAG 0.445946 0.6875
262 MA4 0.444444 0.891892
263 QV4 0.444444 0.733333
264 MAN DGO 0.440678 0.914286
265 3SA 0.44 0.733333
266 Z6J 0.439024 0.742857
267 GLC GLC GLC PO4 SGC GLC 0.439024 0.66
268 AHR 0.439024 0.742857
269 RIB 0.439024 0.742857
270 FUB 0.439024 0.742857
271 32O 0.439024 0.742857
272 T6P 0.438596 0.767442
273 MMA 0.4375 0.857143
274 MBG 0.4375 0.857143
275 GYP 0.4375 0.857143
276 AMG 0.4375 0.857143
277 MAN G63 0.435484 0.653061
278 GDQ GLC 0.435484 0.666667
279 4MU BGC BGC 0.434211 0.767442
280 ISX 0.433333 0.761905
281 MAN 7D1 0.431034 0.888889
282 ACR 0.43038 0.733333
283 QPS 0.43038 0.733333
284 GAL MGC 0.428571 0.702128
285 4MU BGC BGC BGC BGC 0.428571 0.767442
286 GAL NDG FUC 0.422535 0.717391
287 FUC NDG GAL 0.422535 0.717391
288 HMC AGL GLC 0.421053 0.717391
289 KHO 0.421053 0.888889
290 GCS GCS GCS 0.419355 0.767442
291 GCS GCS GCS GCS GCS 0.419355 0.767442
292 GCS GCS GCS GCS GCS GCS 0.419355 0.767442
293 GAL NAG GAL 0.418919 0.702128
294 NGT GAL 0.41791 0.66
295 GAL NGT 0.41791 0.66
296 P3M 0.41791 0.767442
297 GLC GAL NAG GAL FUC A2G 0.417582 0.673469
298 A2G GAL NAG FUC GAL GLC 0.417582 0.673469
299 TUR 0.416667 0.842105
300 BTU 0.416667 0.842105
301 GLC FRU 0.416667 0.842105
302 GLA MAN ABE 0.414286 0.916667
303 NAG NAG BMA 0.413333 0.634615
304 NAG NDG BMA 0.413333 0.634615
305 ACR GLC GLC GLC GLC 0.4125 0.702128
306 ACR GLC 0.4125 0.702128
307 AHR AHR AHR AHR AHR AHR 0.410714 0.857143
308 FUB AHR AHR 0.410714 0.857143
309 VAM 0.409836 0.868421
310 GLF B8D 0.409836 0.775
311 DAF GLC DAF GLC GLC 0.409639 0.702128
312 ACI GLD GLC ACI G6D BGC 0.409639 0.702128
313 AC1 GLC AC1 BGC 0.409639 0.702128
314 ACI G6D GLC ACI G6D BGC 0.409639 0.702128
315 BGC GLC AC1 GLC GLC GLC AC1 0.409639 0.702128
316 ACI GLD GLC GLC GLC ACI GLD GLC GAL 0.409639 0.702128
317 MAN MMA MAN 0.409091 0.942857
318 FUB AHR 0.407407 0.857143
319 AHR AHR 0.407407 0.857143
320 G6D GLC ACI GLD GLC ACI GLD GLC BGC 0.406977 0.653061
321 4U0 0.406593 0.66
322 BGC BGC SSG PIH 0.405063 0.767442
323 GLA MAN RAM ABE 0.405063 0.891892
324 G1P 0.403846 0.697674
325 GL1 0.403846 0.697674
326 XGP 0.403846 0.697674
327 M1P 0.403846 0.697674
328 GLC IFM 0.403226 0.727273
329 MAN IFM 0.403226 0.727273
330 MAN MAN MAN MAN MAN MAN MAN 0.402597 1
331 XZZ BGC BGC 0.402439 0.702128
332 ACG 0.402299 0.695652
333 FUC GAL 0.4 0.941176
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2ZQO; Ligand: NGA; Similar sites found with APoc: 188
This union binding pocket(no: 1) in the query (biounit: 2zqo.bio2) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 1YBU APC None
2 5XG5 A2G None
3 2IMW DDS None
4 2J6U DGT None
5 4UXH T5A None
6 3QDL FMN None
7 4ZVF GAV None
8 3A6T 8OG None
9 2WCV FUC None
10 1TMM HHR None
11 2H1H AFH None
12 1Z4O GL1 1.53846
13 1WD4 AHR 1.53846
14 1YKI NFZ 1.53846
15 1YKI FMN 1.53846
16 3MBG FAD 1.53846
17 2PT9 S4M 1.53846
18 2PT9 2MH 1.53846
19 1ST0 GTG 1.53846
20 1KQB BEZ 1.53846
21 1KQB FMN 1.53846
22 3O55 FAD 1.6
23 4WP9 ZDA 2.30769
24 3S6X SIA GAL BGC 2.30769
25 5TIV A3P 2.30769
26 4C2C ALA VAL PRO ALA 2.30769
27 4BGB ADP 2.30769
28 5OYH T99 3.07692
29 2RCU BUJ 3.07692
30 1W1A NDG 3.07692
31 4F07 FAD 3.07692
32 1VRP ADP 3.07692
33 5DEP UD1 3.07692
34 5KKB BMA NAG MAN MAN MAN MAN MAN MAN MAN 3.07692
35 4NBI D3Y 3.07692
36 3C6K SPD 3.07692
37 3C6K MTA 3.07692
38 1W4R TTP 3.84615
39 1MEX RAC 3.84615
40 4DXD 9PC 3.84615
41 1S4M LUM 3.84615
42 4J6O CIT 3.84615
43 6BC3 SIS 3.84615
44 6BC3 COA 3.84615
45 4NZ4 NDG 3.84615
46 6EQS BV8 3.84615
47 4CLI 5P8 3.84615
48 5J62 FMN 3.84615
49 4H2D FMN 3.84615
50 3PP0 03Q 3.84615
51 1XPJ TLA 3.96825
52 5N9T 8QQ 4.61538
53 4GLW NMN 4.61538
54 1T8U UAP SGN IDS SGN 4.61538
55 2D37 FMN 4.61538
56 2D37 NAD 4.61538
57 1W2D 4IP 4.61538
58 1W2D ADP 4.61538
59 2VJ8 HA2 4.61538
60 6BQ6 TER 4.61538
61 5XDT MB3 4.61538
62 6GW4 CHO 5.38462
63 4MZQ 1VU 5.38462
64 5A89 ADP 5.38462
65 5A89 FMN 5.38462
66 6FRN FMN 5.38462
67 2OHH FMN 5.38462
68 5WGR PM7 5.38462
69 2I8T GDD 5.38462
70 2WLG SOP 5.38462
71 4LOO SB4 5.38462
72 2HJR APR 5.38462
73 2EV9 SKM 5.38462
74 2EV9 NAP 5.38462
75 5AYV NAP 5.38462
76 1N07 FMN 6.15385
77 4LXQ TYD 6.15385
78 4LXQ FON 6.15385
79 2WZV FMN 6.15385
80 4ONC 40B 6.15385
81 4IEN GDP 6.15385
82 4IEN COA 6.15385
83 4BTV RB3 6.15385
84 4WOE ADP 6.15385
85 2FY3 CHT 6.15385
86 3N2S FMN 6.15385
87 2WA4 069 6.15385
88 5HDJ FMN 6.15385
89 4YNM SAM 6.15385
90 2D24 XYS XYS 6.92308
91 1RC0 KT5 6.92308
92 1SYN UMP 6.92308
93 2V1O COA 6.92308
94 1AXW UMP 6.92308
95 5IUW IAC 6.92308
96 5IUW NAD 6.92308
97 1TSD UMP 6.92308
98 1TLC DGP 6.92308
99 4IKR PVP 6.92308
100 1AIQ UMP 6.92308
101 1NCE UMP 6.92308
102 1QK3 5GP 6.92308
103 1F28 UMP 6.92308
104 4QLX FMN 6.92308
105 4D9M 0JO 6.92308
106 1ZPR UMP 6.92308
107 2CYE COA 6.92308
108 2OJW ADP 6.92308
109 3TAY MN0 6.92308
110 4ISK UMP 6.92308
111 3TCT 3MI 7.08661
112 6A9F 9BF 7.69231
113 4MIB 28M 7.69231
114 5H5J FAD 7.69231
115 4DPL NAP 7.69231
116 5ZFJ 9BF 7.69231
117 5A3T MMK 7.69231
118 4LTN NAI 7.69231
119 4LTN FMN 7.69231
120 1EP2 FMN 7.69231
121 1TT8 PHB 7.69231
122 6G9I CXX 7.69231
123 2BW7 ECS 8.46154
124 2BW7 APC 8.46154
125 4B0T ADP 8.46154
126 6C1S EFV 8.46154
127 4TXE 38F 8.46154
128 2DXU BT5 8.46154
129 1MH5 HAL 8.46154
130 2ZXG S23 8.46154
131 1T36 ADP 8.46154
132 4EIL UMP 8.46154
133 5CPS GLC GLC GLC GLC GLC GLC GLC GLC GLC 8.46154
134 2QV6 GTP 9.23077
135 4XBA 5GP 9.23077
136 4XBA GMP 9.23077
137 3MEH THP 9.23077
138 3HAZ FAD 9.23077
139 1V5Y FMN 10
140 5NBW 8SK 10
141 1V5Y 4HC 10
142 2IV2 2MD 10
143 5XQW 8EU 10
144 1CS4 101 10.7692
145 1CS4 FOK 10.7692
146 2WR8 SAH 10.7692
147 3RZ3 U94 10.7692
148 4O1P ANP 10.7692
149 4Z87 GDP 11.5385
150 4AG5 ADP 11.5385
151 1ICV FMN 11.5385
152 2GQR ADP 12.3077
153 6AMI TRP 12.3077
154 6AM8 PLT 12.3077
155 2P4Y C03 13.0769
156 3FUR Z12 13.0769
157 4HEE 14R 13.0769
158 2HFP NSI 13.0769
159 3H0A D30 13.0769
160 2NU8 COA 13.0769
161 4PTZ FMN 13.0769
162 2X2T GAL NGA 13.8462
163 2DW7 SRT 13.8462
164 4G9N NGA 14.6154
165 2BLN FON 14.6154
166 4CRL C1I 14.6154
167 3AJ6 NGA 15.3846
168 4IPH 1FJ 15.4472
169 4AAW R84 16.1538
170 3KDU NKS 17.6923
171 5BVE 4VG 17.6923
172 5MZY 8EZ 17.6923
173 4OWK NGA 18.4615
174 5LRT ADP 19.2308
175 2ISJ FMN 19.2308
176 4LO2 GAL BGC 20
177 1KNM LAT 21.5385
178 1MI3 NAD 21.5385
179 4OUJ LBT 22.3077
180 1T7Q COA 22.3077
181 1T7Q 152 22.3077
182 6EDK 1YA 23.8462
183 3DOO SKM 23.8462
184 4ZGR NGA GAL 25.3846
185 2GQS ADP 26.1538
186 1JQ3 AAT 29.2308
187 5J6C FMN 30
188 3A23 GAL 38.4615
Pocket No.: 2; Query (leader) PDB : 2ZQO; Ligand: NGA; Similar sites found with APoc: 69
This union binding pocket(no: 2) in the query (biounit: 2zqo.bio2) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 5RHN 8BR None
2 5WA9 9ZD None
3 5NI5 8YB None
4 3KV8 FAH None
5 4CQK PIO None
6 4K3H 1OM None
7 4INI AMP None
8 3BL7 DD1 1.53846
9 2I7C AAT 1.53846
10 5OCS FMN 1.53846
11 3U5S FAD 1.5873
12 1JA9 NDP 2.30769
13 4CL6 7SB 2.30769
14 2YIP YIO 2.30769
15 6FA4 D1W 2.30769
16 1OQC FAD 2.4
17 4PHR UDP 3.07692
18 1NB9 ADP 3.07692
19 1NB9 RBF 3.07692
20 6ASY ATP 3.07692
21 5K4W THR 3.07692
22 5VEG FMN 3.84615
23 4WZ8 3W7 4.61538
24 1VPM COA 4.61538
25 4HWT 1B2 4.61538
26 2DJH 3PD UM3 5.21739
27 4OJ8 AKG 5.38462
28 4OJ8 2TQ 5.38462
29 3QJ4 FAD 5.38462
30 2FLI DX5 5.38462
31 2O07 MTA 6.15385
32 5BO9 SIA GAL NGS 6.15385
33 5BO9 CSF 6.15385
34 3WXB NDP 6.15385
35 4NV7 COA 6.15385
36 5MW4 5JU 6.15385
37 3T1A 5MA 6.15385
38 2Q1W NAD 6.15385
39 1X7D NAD 6.92308
40 5F2T PLM 7.69231
41 4WNB 4BN 7.69231
42 4FBL SPD 7.69231
43 1IYE PGU 7.69231
44 2QRD ATP 8.24742
45 3N1S 5GP 8.40336
46 1WPY BTN 8.46154
47 4O8A FAD 8.46154
48 1TIW TFB 8.46154
49 1TIW FAD 8.46154
50 3ORF NAD 8.46154
51 5JIC N7E 9.23077
52 5J75 6GQ 9.23077
53 5O2D 9HH 9.23077
54 4XMF HSM 10
55 3WSJ MK1 11.2069
56 3M54 SAH 11.5385
57 1MT6 SAH 11.5385
58 2X24 X24 11.5385
59 4GAH 0ET 12.3077
60 2J8C U10 12.3077
61 2QEN ADP 13.0769
62 1JJE BYS 13.0769
63 5F3I 5UJ 14.6154
64 3UH0 TSB 15.3846
65 3V1U NAD 16.1538
66 4K49 HFQ 17.6923
67 3VHE 42Q 17.6923
68 5JHD GLY ILE LEU GLY PHE VAL PHE THR LEU 20
69 4IV9 FAD 20.7692
Pocket No.: 3; Query (leader) PDB : 2ZQO; Ligand: NGA; Similar sites found with APoc: 23
This union binding pocket(no: 3) in the query (biounit: 2zqo.bio1) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 5HPZ 68G None
2 1JUV NDP None
3 2ZX2 RAM None
4 2QIA U20 1.53846
5 4IQY AR6 2.30769
6 4PZ2 NAD 3.07692
7 2Y88 2ER 3.07692
8 4H6Q TFB 3.84615
9 4G1V FAD 4.61538
10 1UM0 FMN 5.38462
11 3KCC CMP 5.38462
12 4S3R 7SA 6.15385
13 2OYS FMN 6.92308
14 2GCG NDP 6.92308
15 5VW2 NAP 7.69231
16 5VW2 FDA 7.69231
17 4R81 FMN 7.69231
18 3KJS NAP 8.46154
19 5CPS GLC GLC GLC GLC GLC GLC GLC GLC 8.46154
20 2IO8 ADP 10.7692
21 2J3M ATP 11.5385
22 2PTZ PAH 11.5385
23 2XCG XCG 13.0769
Pocket No.: 4; Query (leader) PDB : 2ZQO; Ligand: NGA; Similar sites found with APoc: 65
This union binding pocket(no: 4) in the query (biounit: 2zqo.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 2VG1 FPP None
2 3R35 4CO None
3 2FXU ATP 3.07692
4 4B1X ATP 3.07692
5 4B1V ATP 3.07692
6 3QKT ANP 3.07692
7 5EZ7 FAD 3.84615
8 5DOZ NDP 3.84615
9 5VC5 96M 3.84615
10 3T2C 13P 3.84615
11 3GE7 AFQ 4.61538
12 1XHC FAD 4.61538
13 1MR3 G3D 4.61538
14 4C5N ACP 4.61538
15 3N2O AG2 4.61538
16 1PN4 HDC 5.38462
17 4ZRN NAD 5.38462
18 4ZRN UPG 5.38462
19 6HLX G9Z 5.38462
20 4EIP FAD 5.38462
21 4EIP K2C 5.38462
22 1JG3 VAL TYR PRO IAS HIS ALA 5.38462
23 3WBZ ATP 5.38462
24 3CTL S6P 6.15385
25 5EIN NAP 6.15385
26 3C8Z 5CA 6.15385
27 4OB6 S2T 6.15385
28 4I4S LAT 6.92308
29 6GAS FAD 6.92308
30 5JBE GLC GLC GLC GLC GLC 7.69231
31 1GRO ICT 7.69231
32 4M38 SAH 7.69231
33 4M37 SAH 7.69231
34 3HKW IX6 8.46154
35 3FC4 EDO 8.46154
36 3AKK ADP 8.46154
37 3KO8 NAD 9.23077
38 4YMX ARG 9.23077
39 5OC1 FAD 10
40 1WUU ANP 10
41 1SB8 NAD 10.7692
42 1SB8 UD2 10.7692
43 2BES RES 10.7692
44 1KPH 10A 10.7692
45 1RE0 AFB 11.5385
46 5U3F 7TS 12.3077
47 2HGS ADP 12.3077
48 1ON3 MCA 13.0769
49 2IBN I1N 13.0769
50 4FE2 ADP 13.8462
51 1GAR U89 14.6154
52 5D4V SAH 15.3846
53 3LU1 NAD 15.3846
54 4BVA NDP 16.1538
55 4BVA T3 16.1538
56 3KAL ADP 16.1538
57 1QNF FAD 16.1538
58 1OFL ASG GCD 16.9231
59 2PZM NAD 16.9231
60 2PZM UDP 16.9231
61 3LLI FAD 17.6923
62 1ZBQ NAD 18.4615
63 3H0L ADP 19.2308
64 1X92 M7P 20.7692
65 3BXD INS 22.3077
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