Receptor
PDB id Resolution Class Description Source Keywords
2D0E 2.15 Å EC: 1.14.-.- SUBSTRATE ASSITED IN OXYGEN ACTIVATION IN CYTOCHROME P450 15 STREPTOMYCES COELICOLOR STREPTOMYCES CYTOCHROME P450 OXIDOREDUCTASE CYP158A2 PROTTRANSFER DIOXYGEN ACTIVATION 2-HYDROXY-1 4-NAPHTHOQUINONOXIDOREDUCTASE
Ref.: ROLE OF ACTIVE SITE WATER MOLECULES AND SUBSTRATE H GROUPS IN OXYGEN ACTIVATION BY CYTOCHROME P450 158A MECHANISM OF PROTON TRANSFER J.BIOL.CHEM. V. 280 42188 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
HEM A:408;
 Part of Protein;
 none;
 submit data
616.487 C34 H32 Fe N4 O4 Cc1c2...
NQ A:409;
A:410;
 Valid;
Valid;
 none;
none;
 Kd = 43 uM
174.153 C10 H6 O3 c1ccc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2D09 1.8 Å EC: 1.14.-.- A ROLE FOR ACTIVE SITE WATER MOLECULES AND HYDROXYL GROUPS O SUBSTRATE FOR OXYGEN ACTIVATION IN CYTOCHROME P450 158A2 STREPTOMYCES COELICOLOR STREPTOMYCES CYTOCHROME P450 OXIDOREDUCTASE CYP158A2 PROTTRANSFER DIOXYGEN ACTIVATION OXIDOREDUCTASE
Ref.: ROLE OF ACTIVE SITE WATER MOLECULES AND SUBSTRATE H GROUPS IN OXYGEN ACTIVATION BY CYTOCHROME P450 158A MECHANISM OF PROTON TRANSFER J.BIOL.CHEM. V. 280 42188 2005
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 20 families.
1 1S1F - PIM C9 H8 N2 c1ccc(cc1)....
2 2D09 Kd = 7.3 uM FLV C10 H6 O5 c1c(cc(c2c....
3 1T93 - FLV C10 H6 O5 c1c(cc(c2c....
4 2D0E Kd = 43 uM NQ C10 H6 O3 c1ccc2c(c1....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 18 families.
1 2NZ5 Kd = 10.5 uM 226 C10 H8 O5 c1c(cc(c2c....
2 1S1F - PIM C9 H8 N2 c1ccc(cc1)....
3 2D09 Kd = 7.3 uM FLV C10 H6 O5 c1c(cc(c2c....
4 1T93 - FLV C10 H6 O5 c1c(cc(c2c....
5 2D0E Kd = 43 uM NQ C10 H6 O3 c1ccc2c(c1....
50% Homology Family (53)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 14 families.
1 3A50 - VD3 C27 H44 O CC(C)CCC[C....
2 3A51 - VDY C27 H44 O2 C[C@H](CCC....
3 5FOI Kd = 1 nM MY8 C29 H49 N O6 CC[C@@H]1[....
4 5GWE Kd = 62 uM GWM C7 H9 O4 P Cc1ccc(cc1....
5 5XJN - 88L C8 H11 O4 P CCc1ccc(cc....
6 4OQR Kd = 29.3 uM 2UO C23 H34 O5 CC[C@H](C)....
7 4UBS Kd = 65 uM DIF C14 H11 Cl2 N O2 c1ccc(c(c1....
8 5L1O Kd = 7.2 uM 7PF C15 H18 O5 CC1(C[C@H]....
9 5L1U Kd = 340 uM 7PF C15 H18 O5 CC1(C[C@H]....
10 5L1S Kd = 160 uM 7PF C15 H18 O5 CC1(C[C@H]....
11 5L1V Kd = 43 uM 7PF C15 H18 O5 CC1(C[C@H]....
12 5L1Q Kd = 170 uM 7DF C15 H20 O5 CC1(C[C@H]....
13 5L1P - 7PT C15 H16 O5 C[C@H]1[C@....
14 2NZ5 Kd = 10.5 uM 226 C10 H8 O5 c1c(cc(c2c....
15 5IT1 - 2OH C15 H16 O2 CC(C)(c1cc....
16 2WI9 Kd = 309 uM 1D2 C20 H39 N O3 C[C@@H]1C[....
17 2VZM Kd = 171.9 uM NRB C28 H47 N O7 CC[C@@H]1[....
18 4B7S Kd = 81 uM QLE C22 H37 N O5 CC[C@@H]1[....
19 3ZK5 Kd = 118 uM Z18 C21 H35 N O5 CC[C@@H]1[....
20 5X7E - 7ZU C28 H44 O3 C[C@H](/C=....
21 2ZBZ - VDX C27 H44 O3 C[C@H](CCC....
22 3CV9 - VDX C27 H44 O3 C[C@H](CCC....
23 2XBK Kd = 4 uM XBK C33 H47 N O12 C[C@@H]1CC....
24 6ZI7 - QR8 C20 H36 O6 C[C@H]1C[C....
25 6ZHZ - QR8 C20 H36 O6 C[C@H]1C[C....
26 6ZI3 - DEB C21 H38 O6 CC[C@@H]1[....
27 6M4P - F4O C40 H53 N O14 Cc1c2c(c3c....
28 1Z8Q - DEB C21 H38 O6 CC[C@@H]1[....
29 1Z8P - DEB C21 H38 O6 CC[C@@H]1[....
30 1JIN - KTN C26 H28 Cl2 N4 O4 CC(=O)N1CC....
31 1JIO - DEB C21 H38 O6 CC[C@@H]1[....
32 1Z8O - DEB C21 H38 O6 CC[C@@H]1[....
33 1S1F - PIM C9 H8 N2 c1ccc(cc1)....
34 2D09 Kd = 7.3 uM FLV C10 H6 O5 c1c(cc(c2c....
35 1T93 - FLV C10 H6 O5 c1c(cc(c2c....
36 2D0E Kd = 43 uM NQ C10 H6 O3 c1ccc2c(c1....
37 1XQD Kd = 0.07 mM DND C21 H27 N6 O15 P2 c1cc(c[n+]....
38 6GK6 Kd = 2.1 uM MYR C14 H28 O2 CCCCCCCCCC....
39 5L91 Kd = 91 uM C0R C21 H30 O4 C[C@]12CCC....
40 5L94 Kd = 105 uM TES C19 H28 O2 C[C@]12CC[....
41 4AW3 - MYV C37 H61 N O12 CC[C@@H]1[....
42 2Y5N - MYV C37 H61 N O12 CC[C@@H]1[....
43 3ZSN - MIV C37 H61 N O11 CC[C@@H]1[....
44 2Y98 - MIV C37 H61 N O11 CC[C@@H]1[....
45 2Y5Z - ZM3 C36 H59 N O11 CC[C@@H]1[....
46 2YCA - ZM3 C36 H59 N O11 CC[C@@H]1[....
47 2Y46 - MIV C37 H61 N O11 CC[C@@H]1[....
48 3WVS - RRM C32 H48 O7 CCCC[C@H]1....
49 6TO2 Kd = 20 nM NQ8 C19 H30 O C[C@@]12CC....
50 4J6C - STR C21 H30 O2 CC(=O)[C@H....
51 4JBT - ASD C19 H26 O2 C[C@]12CCC....
52 4J6B - PLO C21 H32 O2 CC(=O)[C@H....
53 4J6D - TES C19 H28 O2 C[C@]12CC[....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: NQ; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 NQ 1 1
2 VK3 0.45 0.72
Similar Ligands (3D)
Ligand no: 1; Ligand: NQ; Similar ligands found: 984
No: Ligand Similarity coefficient
1 RXA 1.0000
2 PYQ 0.9799
3 37T 0.9788
4 TTL 0.9787
5 PE0 0.9764
6 9KT 0.9763
7 AJ2 0.9749
8 MEW 0.9746
9 Q24 0.9742
10 M5K 0.9737
11 12Q 0.9733
12 AQO 0.9731
13 7W1 0.9729
14 J9W 0.9726
15 M6N 0.9724
16 KJH 0.9722
17 LI6 0.9715
18 M1Q 0.9715
19 AZ8 0.9714
20 BGC 0.9711
21 HQT 0.9710
22 4HC 0.9703
23 2ZQ 0.9692
24 5QX 0.9685
25 PXL 0.9683
26 TEP 0.9674
27 NID 0.9663
28 MT0 0.9661
29 9DG 0.9655
30 HZQ 0.9653
31 7ZE 0.9652
32 495 0.9640
33 KJY 0.9637
34 AZA 0.9633
35 12B 0.9632
36 SKA 0.9632
37 XAN 0.9625
38 5WY 0.9624
39 INE 0.9624
40 GUN 0.9621
41 EA1 0.9610
42 CFF 0.9610
43 7NI 0.9606
44 Q6T 0.9604
45 URC 0.9600
46 QBK 0.9596
47 141 0.9590
48 XHP 0.9588
49 GLC 0.9586
50 IGA 0.9582
51 ZVO 0.9572
52 AZ9 0.9571
53 AKH 0.9566
54 G3F 0.9565
55 QPR 0.9563
56 67N 0.9562
57 M1A 0.9559
58 44W 0.9558
59 B62 0.9555
60 FDB 0.9548
61 OTW 0.9548
62 HJP 0.9548
63 BDP 0.9546
64 QX4 0.9545
65 0N7 0.9543
66 209 0.9540
67 A2F 0.9538
68 JUG 0.9533
69 PX7 0.9525
70 DQU 0.9524
71 HQD 0.9517
72 42C 0.9516
73 NTZ 0.9515
74 8S0 0.9514
75 HLZ 0.9513
76 24W 0.9513
77 G1O 0.9512
78 APZ 0.9510
79 226 0.9510
80 FLV 0.9504
81 R8V 0.9504
82 H33 0.9503
83 GCS 0.9501
84 NDM 0.9501
85 5SG 0.9501
86 B57 0.9501
87 BTY 0.9498
88 CFP 0.9498
89 XAZ 0.9498
90 YH7 0.9497
91 6ME 0.9496
92 X8D 0.9494
93 5IQ 0.9493
94 75K 0.9488
95 AZG 0.9486
96 5RN 0.9485
97 680 0.9483
98 1NP 0.9483
99 DRL 0.9482
100 8TX 0.9481
101 IV2 0.9476
102 1SQ 0.9476
103 290 0.9470
104 6AP 0.9470
105 B55 0.9470
106 5Q0 0.9465
107 1XM 0.9463
108 BOA 0.9463
109 CTL 0.9460
110 HQY 0.9460
111 6BL 0.9457
112 44V 0.9457
113 B60 0.9456
114 ES1 0.9452
115 PHH 0.9451
116 4MU 0.9451
117 DX4 0.9450
118 PFB 0.9446
119 0P6 0.9444
120 4YS 0.9444
121 9MG 0.9443
122 VNL 0.9443
123 3HA 0.9441
124 MVN 0.9439
125 5JQ 0.9439
126 G5V 0.9438
127 B53 0.9438
128 15L 0.9436
129 N5J 0.9433
130 PEY 0.9433
131 6GU 0.9430
132 3WA 0.9429
133 G6D 0.9428
134 3F0 0.9427
135 JPZ 0.9425
136 MO8 0.9425
137 0FO 0.9421
138 BHA 0.9421
139 5CU 0.9418
140 MUA 0.9416
141 MAQ 0.9410
142 ICO 0.9410
143 JBQ 0.9409
144 GIO 0.9409
145 FOT 0.9408
146 8CM 0.9408
147 1LQ 0.9406
148 4FS 0.9402
149 FA0 0.9402
150 CLZ 0.9401
151 NOJ 0.9400
152 5NU 0.9397
153 6VD 0.9397
154 DBH 0.9396
155 1LM 0.9393
156 JBK 0.9393
157 UAN 0.9392
158 Z5P 0.9390
159 IJZ 0.9389
160 FE DB1 0.9388
161 HH8 0.9388
162 BCP 0.9387
163 4M0 0.9386
164 DOB 0.9386
165 03V 0.9385
166 3MG 0.9382
167 2AQ 0.9381
168 COU 0.9380
169 4ME 0.9380
170 39A 0.9375
171 4AA 0.9375
172 ISE 0.9374
173 UNC 0.9373
174 M2K 0.9372
175 M1H 0.9372
176 GCU 0.9372
177 0FN 0.9371
178 3M0 0.9367
179 TTY 0.9366
180 E7Z 0.9365
181 OCH 0.9365
182 0CU 0.9363
183 O72 0.9357
184 HH5 0.9357
185 92K 0.9356
186 7VS 0.9354
187 JBH 0.9353
188 TBS 0.9351
189 NDH 0.9350
190 BEA 0.9350
191 ES5 0.9348
192 2AK 0.9347
193 ISN 0.9347
194 JB5 0.9346
195 DNA 0.9346
196 TOF 0.9345
197 LDR 0.9345
198 3IT 0.9344
199 H42 0.9344
200 18N 0.9343
201 PQ0 0.9340
202 HHA 0.9340
203 RPQ 0.9338
204 M0Q 0.9335
205 5JL 0.9331
206 HNQ 0.9326
207 FBG 0.9325
208 28N 0.9325
209 A7W 0.9323
210 K17 0.9322
211 2KA 0.9321
212 2FQ 0.9319
213 KT7 0.9317
214 M0W 0.9316
215 3RK 0.9316
216 25W 0.9316
217 5WX 0.9314
218 4XH 0.9314
219 2D0 0.9313
220 7HQ 0.9311
221 DPZ 0.9310
222 7W4 0.9309
223 KIA 0.9308
224 6F0 0.9308
225 KIB 0.9308
226 GRE 0.9303
227 GAL 0.9303
228 CWS 0.9302
229 8XQ 0.9300
230 GTR 0.9297
231 9AP 0.9296
232 5WV 0.9293
233 8IG 0.9292
234 SAL 0.9286
235 6M1 0.9286
236 F12 0.9284
237 EQT 0.9283
238 PDC 0.9282
239 ES0 0.9280
240 KKN 0.9280
241 PRF 0.9279
242 DIN 0.9278
243 G3E 0.9276
244 SHG 0.9275
245 4KL 0.9273
246 BE2 0.9272
247 5RG 0.9272
248 BSP 0.9272
249 2ZV 0.9272
250 ZYR 0.9271
251 BTE 0.9268
252 H5B 0.9267
253 XXR 0.9267
254 DNC 0.9266
255 C2U 0.9266
256 4TU 0.9265
257 K32 0.9265
258 CWM 0.9264
259 7ME 0.9263
260 ADK 0.9260
261 3MA 0.9260
262 LGC 0.9260
263 ODO 0.9259
264 KUF 0.9256
265 INS 0.9256
266 HTP 0.9252
267 D07 0.9245
268 5M0 0.9244
269 3Z8 0.9244
270 92P 0.9243
271 PRZ 0.9241
272 C2Y 0.9241
273 MVL 0.9240
274 32X 0.9235
275 GDE 0.9235
276 ES7 0.9231
277 K22 0.9230
278 DBJ 0.9230
279 7WR 0.9229
280 CTS 0.9229
281 7VJ 0.9229
282 RM1 0.9228
283 I3A 0.9227
284 UEG 0.9224
285 PHT 0.9224
286 GTQ 0.9224
287 1XN 0.9223
288 MRW 0.9222
289 9FL 0.9222
290 3PF 0.9219
291 SE2 0.9218
292 86J 0.9218
293 XYP 0.9217
294 AEZ 0.9217
295 NTM 0.9217
296 ES6 0.9217
297 GIM 0.9216
298 4RU 0.9214
299 Q88 0.9213
300 HFB 0.9211
301 4Z4 0.9211
302 GJP 0.9211
303 OA3 0.9210
304 5OB 0.9210
305 DQN 0.9210
306 2LY 0.9207
307 MS9 0.9207
308 K6X 0.9207
309 D48 0.9205
310 FDR 0.9204
311 0W8 0.9204
312 7B4 0.9199
313 5QY 0.9197
314 KYA 0.9196
315 1HN 0.9195
316 SOE 0.9194
317 6AI 0.9194
318 4SV 0.9192
319 6CS 0.9189
320 3U4 0.9188
321 4AN 0.9187
322 BP1 0.9184
323 F5B 0.9184
324 7B3 0.9183
325 BZX 0.9181
326 BCF 0.9180
327 4JQ 0.9179
328 DHK 0.9178
329 5NS 0.9178
330 DHQ 0.9178
331 M1E 0.9177
332 9TZ 0.9177
333 LKA 0.9176
334 DIU 0.9175
335 8ZE 0.9173
336 PXM 0.9172
337 FYU 0.9171
338 329 0.9170
339 JKZ 0.9170
340 I6G 0.9169
341 Q71 0.9167
342 54G 0.9165
343 23A 0.9165
344 SRO 0.9165
345 JTH 0.9165
346 PH2 0.9164
347 LXC 0.9164
348 HLD 0.9163
349 6MP 0.9162
350 7WV 0.9161
351 10L 0.9160
352 06B 0.9160
353 YSO 0.9160
354 KJU 0.9159
355 AA 0.9156
356 2H5 0.9155
357 JAE 0.9154
358 EVA 0.9153
359 3DM 0.9150
360 7WA 0.9149
361 EJZ 0.9149
362 MT5 0.9148
363 XQG 0.9147
364 30G 0.9146
365 BK9 0.9145
366 1IT 0.9145
367 J5I 0.9143
368 14O 0.9142
369 SYV 0.9142
370 MT8 0.9141
371 ADZ 0.9141
372 2HQ 0.9140
373 X05 0.9140
374 MHK 0.9140
375 5RO 0.9140
376 FBB 0.9139
377 J9Q 0.9138
378 BBF 0.9137
379 JKE 0.9134
380 3FH 0.9132
381 HPA 0.9131
382 5H1 0.9130
383 MQN 0.9130
384 149 0.9130
385 ASO 0.9129
386 F60 0.9128
387 9CA 0.9127
388 ADE 0.9127
389 SHA 0.9127
390 82I 0.9126
391 1P7 0.9125
392 5MI 0.9124
393 SWD 0.9123
394 F0J 0.9123
395 1WD 0.9123
396 KLW 0.9122
397 2K4 0.9122
398 BMA 0.9122
399 ORO 0.9121
400 4JT 0.9120
401 9HX 0.9120
402 2FY 0.9120
403 K8X 0.9119
404 3ID 0.9118
405 SWA 0.9118
406 7HP 0.9116
407 QX2 0.9115
408 N2I 0.9115
409 9DA 0.9115
410 PCI 0.9115
411 ET2 0.9114
412 Q7A 0.9113
413 N8Y 0.9111
414 H6B 0.9111
415 X09 0.9110
416 GOG 0.9110
417 5MB 0.9110
418 8WO 0.9109
419 BZ3 0.9106
420 8MO 0.9106
421 FUL 0.9105
422 LSA 0.9104
423 6NT 0.9103
424 DMD 0.9103
425 0TU 0.9103
426 IBF 0.9103
427 TWO 0.9102
428 XQ0 0.9100
429 GTZ 0.9100
430 O2A 0.9098
431 5NE 0.9096
432 K2T 0.9095
433 CLW 0.9095
434 97T 0.9094
435 HHR 0.9093
436 GV9 0.9093
437 36R 0.9093
438 ES2 0.9087
439 0HO 0.9086
440 QUZ 0.9085
441 1P8 0.9085
442 4YO 0.9084
443 GCB 0.9084
444 BPU 0.9084
445 0GZ 0.9084
446 5MK 0.9084
447 4NC 0.9082
448 NPY 0.9081
449 5XC 0.9080
450 JBE 0.9080
451 11S 0.9079
452 OXC 0.9078
453 GLA 0.9077
454 QWW 0.9075
455 DNF 0.9073
456 AJV 0.9071
457 27B 0.9069
458 M4E 0.9068
459 ES9 0.9066
460 20J 0.9066
461 3NY 0.9064
462 5VL 0.9061
463 F3B 0.9061
464 3C1 0.9060
465 KFH 0.9060
466 KDV 0.9060
467 QAT 0.9059
468 0F9 0.9059
469 SKM 0.9059
470 NVU 0.9058
471 ES4 0.9058
472 LZ2 0.9057
473 5B1 0.9056
474 EXO 0.9056
475 5VJ 0.9056
476 LZM 0.9055
477 V55 0.9054
478 9R5 0.9053
479 39O 0.9051
480 SVN 0.9051
481 HMU 0.9051
482 VGD 0.9050
483 ANF 0.9048
484 H4N 0.9046
485 DHB 0.9046
486 AIN 0.9045
487 0JD 0.9044
488 F81 0.9043
489 UFO 0.9043
490 42A 0.9043
491 HMH 0.9043
492 DX3 0.9043
493 PM6 0.9042
494 GJS 0.9041
495 GYE 0.9041
496 QAS 0.9040
497 KYD 0.9039
498 52C 0.9038
499 2HU 0.9037
500 ALL 0.9037
501 ZZ8 0.9033
502 FK1 0.9031
503 2ZM 0.9031
504 5GU 0.9031
505 3C2 0.9030
506 1X7 0.9027
507 2FG 0.9026
508 0HN 0.9024
509 PJW 0.9023
510 1U6 0.9020
511 CH9 0.9019
512 15N 0.9017
513 AHR 0.9016
514 FGZ 0.9015
515 5NI 0.9014
516 WOO 0.9012
517 GM7 0.9011
518 IPB 0.9010
519 SYA 0.9010
520 HKD 0.9009
521 NNO 0.9008
522 LT2 0.9008
523 SOR 0.9008
524 3MB 0.9006
525 PD2 0.9004
526 5VM 0.9003
527 GCW 0.9003
528 GZ8 0.9003
529 BNT 0.9002
530 6NI 0.9002
531 ARP 0.9002
532 XYS 0.9001
533 MR1 0.9001
534 8HC 0.9001
535 INO 0.9001
536 SX1 0.9001
537 JIF 0.8999
538 P3K 0.8996
539 K3Q 0.8995
540 F05 0.8995
541 BCU 0.8995
542 34D 0.8992
543 FBT 0.8991
544 5WU 0.8990
545 173 0.8990
546 23J 0.8990
547 MAN 0.8989
548 OVM 0.8988
549 1F1 0.8987
550 4A3 0.8987
551 MZB 0.8985
552 B5D 0.8984
553 JFD 0.8983
554 NAG 0.8981
555 LDP 0.8981
556 DOR 0.8981
557 TH7 0.8981
558 948 0.8981
559 FHB 0.8980
560 MYJ 0.8980
561 TGX 0.8980
562 ABI 0.8979
563 THA 0.8979
564 8G0 0.8978
565 M5N 0.8977
566 CN0 0.8976
567 DRG 0.8975
568 4M4 0.8975
569 RAM 0.8975
570 ROI 0.8973
571 F9Y 0.8972
572 3A9 0.8970
573 93K 0.8970
574 0FK 0.8969
575 G12 0.8969
576 P9P 0.8969
577 ABV 0.8966
578 JU2 0.8965
579 15E 0.8964
580 HA7 0.8964
581 YQA 0.8963
582 1DW 0.8962
583 GOX 0.8962
584 DEE 0.8960
585 GXY 0.8960
586 0XT 0.8960
587 8NY 0.8959
588 2AL 0.8957
589 XX2 0.8955
590 XXP 0.8955
591 CHB 0.8954
592 JR2 0.8953
593 GNM 0.8953
594 64C 0.8951
595 2HO 0.8950
596 2CK 0.8950
597 TIY 0.8949
598 G2F 0.8949
599 3GQ 0.8947
600 Q77 0.8946
601 EYK 0.8944
602 KBG 0.8942
603 6M9 0.8942
604 GIV 0.8942
605 3J8 0.8940
606 IFL 0.8940
607 QSB 0.8937
608 GZL 0.8933
609 8WT 0.8933
610 9EW 0.8933
611 F1A 0.8933
612 3HM 0.8932
613 1KP 0.8931
614 E3D 0.8931
615 ADA 0.8930
616 CWJ 0.8930
617 PHB 0.8929
618 2EC 0.8928
619 GCV 0.8927
620 CKA 0.8926
621 QSH 0.8926
622 94W 0.8923
623 1GN 0.8922
624 AW5 0.8922
625 E1T 0.8921
626 SXS 0.8920
627 2A7 0.8919
628 TT4 0.8919
629 NPO 0.8919
630 ZZZ 0.8919
631 PA1 0.8918
632 94B 0.8918
633 OMD 0.8917
634 HIS 0.8917
635 5CL 0.8916
636 6RQ 0.8915
637 3DO 0.8915
638 T6C 0.8913
639 HLR 0.8912
640 6M4 0.8911
641 4CS 0.8911
642 39U 0.8910
643 L7T 0.8908
644 JG8 0.8908
645 9TW 0.8908
646 XM0 0.8907
647 FB1 0.8907
648 270 0.8907
649 AJY 0.8904
650 EKZ 0.8904
651 UQ 0.8903
652 OTD 0.8903
653 7MX 0.8901
654 YIO 0.8901
655 FP1 0.8899
656 8GC 0.8898
657 AX7 0.8897
658 3HB 0.8896
659 ONR 0.8896
660 IHB 0.8896
661 R9Y 0.8893
662 MWP 0.8891
663 2A9 0.8890
664 0RW 0.8889
665 KGK 0.8888
666 S76 0.8888
667 7MH 0.8886
668 X6X 0.8886
669 MBG 0.8885
670 GAB 0.8884
671 8W9 0.8884
672 35C 0.8884
673 60Q 0.8883
674 I1N 0.8882
675 LT8 0.8881
676 PAB 0.8881
677 DBX 0.8880
678 D1X 0.8877
679 GTL 0.8877
680 67X 0.8876
681 VXX 0.8876
682 PQK 0.8875
683 DIE 0.8873
684 JXN 0.8873
685 HA5 0.8870
686 IBM 0.8869
687 HBD 0.8868
688 VOH 0.8867
689 JAW 0.8866
690 ZZT 0.8866
691 ARB 0.8864
692 NOY 0.8863
693 UFV 0.8862
694 ZB1 0.8862
695 2MI 0.8861
696 P92 0.8860
697 RD4 0.8860
698 VNJ 0.8860
699 261 0.8859
700 8H8 0.8857
701 K37 0.8855
702 EUG 0.8855
703 JB8 0.8854
704 FCB 0.8852
705 SJ5 0.8851
706 LCN 0.8849
707 4HM 0.8848
708 3AB 0.8848
709 D3M 0.8847
710 KBB 0.8845
711 5HN 0.8844
712 2BG 0.8841
713 FBV 0.8841
714 8GK 0.8841
715 HXX 0.8839
716 OW4 0.8838
717 MFB 0.8838
718 PBA 0.8838
719 4XV 0.8837
720 RM4 0.8837
721 JDN 0.8835
722 537 0.8834
723 TIU 0.8834
724 TVP 0.8831
725 3NT 0.8830
726 J01 0.8830
727 E5X 0.8830
728 1Y6 0.8827
729 OVV 0.8825
730 F31 0.8825
731 GXL 0.8823
732 826 0.8823
733 ZWZ 0.8822
734 IFP 0.8819
735 1WG 0.8818
736 GT0 0.8814
737 MXX 0.8813
738 582 0.8810
739 1U1 0.8810
740 JA8 0.8809
741 M6Z 0.8809
742 2F6 0.8809
743 4VS 0.8808
744 X0V 0.8808
745 53C 0.8808
746 FUC 0.8808
747 4MA 0.8808
748 B56 0.8807
749 FLC 0.8807
750 A29 0.8804
751 XIY 0.8804
752 GOO 0.8804
753 FDK 0.8802
754 PBZ 0.8801
755 DPT 0.8801
756 2MN 0.8800
757 QIC 0.8800
758 SLS 0.8798
759 3TJ 0.8797
760 9PY 0.8796
761 DMJ 0.8794
762 174 0.8794
763 2D3 0.8793
764 4V6 0.8793
765 XQK 0.8793
766 E1K 0.8790
767 JND 0.8790
768 60P 0.8789
769 8OZ 0.8788
770 AMG 0.8787
771 RHU 0.8787
772 ASC 0.8785
773 R8S 0.8785
774 A13 0.8785
775 4XR 0.8780
776 CCV 0.8780
777 QWN 0.8780
778 P72 0.8780
779 C9E 0.8780
780 WCE 0.8777
781 GLT 0.8776
782 NGO 0.8776
783 RNS 0.8775
784 8XL 0.8774
785 GAF 0.8774
786 KIF 0.8774
787 4XS 0.8773
788 3QV 0.8771
789 G4D 0.8770
790 293 0.8769
791 9ZE 0.8768
792 TSS 0.8768
793 24B 0.8767
794 NDG 0.8765
795 9FE 0.8764
796 7FF 0.8764
797 0MK 0.8764
798 3BZ 0.8763
799 BRT 0.8762
800 49O 0.8762
801 E7R 0.8761
802 1QP 0.8761
803 1M2 0.8758
804 NSP 0.8757
805 1XA 0.8757
806 Z82 0.8757
807 DFB 0.8753
808 FUF 0.8747
809 4P5 0.8743
810 EN1 0.8739
811 PFL 0.8737
812 3R6 0.8735
813 GSY 0.8735
814 2JK 0.8731
815 TXW 0.8729
816 EV0 0.8729
817 FSW 0.8727
818 3SK 0.8726
819 2SX 0.8726
820 ZZ3 0.8725
821 7MU 0.8723
822 PNZ 0.8723
823 JZ3 0.8721
824 JLZ 0.8721
825 BA5 0.8720
826 ANN 0.8720
827 AC6 0.8719
828 APS 0.8719
829 4FH 0.8718
830 GCO 0.8717
831 IFM 0.8717
832 FCA 0.8717
833 TBP 0.8714
834 DK1 0.8713
835 W81 0.8712
836 FH2 0.8711
837 DEN 0.8711
838 QQQ 0.8711
839 IPZ 0.8710
840 J9T 0.8708
841 AN3 0.8708
842 BHO 0.8706
843 1A7 0.8705
844 6KT 0.8705
845 H62 0.8704
846 AY4 0.8703
847 IUP 0.8703
848 BPY 0.8703
849 IAC 0.8702
850 8NX 0.8700
851 NMJ 0.8700
852 K44 0.8699
853 ESI 0.8699
854 7I2 0.8697
855 12M 0.8697
856 QXW 0.8697
857 7D2 0.8696
858 NLA 0.8695
859 FA6 0.8694
860 150 0.8693
861 2K8 0.8693
862 54X 0.8690
863 7CT 0.8690
864 MMA 0.8690
865 68A 0.8689
866 GBD 0.8687
867 HDH 0.8686
868 N3W 0.8686
869 KJ5 0.8686
870 344 0.8685
871 FHN 0.8684
872 6XI 0.8683
873 2CQ 0.8680
874 IND 0.8680
875 FBU 0.8680
876 PYD 0.8679
877 HHS 0.8678
878 HQJ 0.8673
879 4SX 0.8673
880 PBR 0.8672
881 K5W 0.8671
882 3XX 0.8670
883 L99 0.8669
884 F6P 0.8668
885 4ZC 0.8668
886 TFU 0.8667
887 IDM 0.8666
888 091 0.8665
889 MNM 0.8662
890 SR4 0.8661
891 BZI 0.8660
892 PYG 0.8660
893 51R 0.8659
894 GAG 0.8657
895 NK 0.8657
896 3Z7 0.8657
897 HX3 0.8656
898 DGJ 0.8651
899 AZF 0.8647
900 OVP 0.8641
901 TH0 0.8640
902 X0W 0.8640
903 MBD 0.8638
904 NGT 0.8636
905 TDR 0.8635
906 FA3 0.8634
907 GVH 0.8633
908 K97 0.8632
909 URF 0.8632
910 0TR 0.8632
911 LZ1 0.8632
912 SYR 0.8628
913 0R1 0.8627
914 BZF 0.8627
915 W8G 0.8627
916 KOJ 0.8626
917 4JP 0.8625
918 NCD 0.8622
919 MPI 0.8621
920 EMZ 0.8620
921 WBU 0.8620
922 BEN 0.8619
923 BEZ 0.8619
924 1AL 0.8619
925 OXZ 0.8618
926 6PC 0.8618
927 286 0.8617
928 MFU 0.8616
929 XM5 0.8616
930 HBA 0.8612
931 2GS 0.8610
932 HBO 0.8610
933 ISZ 0.8605
934 0CT 0.8604
935 43M 0.8603
936 BAM 0.8603
937 NCT 0.8602
938 MCT 0.8601
939 NSG 0.8601
940 NIO 0.8600
941 F69 0.8598
942 J6W 0.8598
943 NBZ 0.8597
944 TYL 0.8596
945 0R0 0.8595
946 FCR 0.8593
947 ICP 0.8590
948 5UC 0.8588
949 RIB 0.8588
950 XYD 0.8588
951 1MC 0.8585
952 6E8 0.8585
953 069 0.8585
954 NGA 0.8582
955 BDF 0.8582
956 ZXD 0.8581
957 XBZ 0.8579
958 DHR 0.8577
959 GMN 0.8576
960 UNU 0.8574
961 L3Q 0.8573
962 MWM 0.8571
963 ENL 0.8571
964 2AC 0.8570
965 BZ2 0.8565
966 N0Z 0.8564
967 QOS 0.8563
968 GYP 0.8562
969 JZ9 0.8560
970 4ZE 0.8559
971 TC7 0.8558
972 FLM 0.8558
973 4HO 0.8553
974 2MP 0.8552
975 K25 0.8551
976 34A 0.8550
977 2O6 0.8550
978 PZA 0.8549
979 TNF 0.8549
980 A1U 0.8548
981 4JO 0.8545
982 3CE 0.8544
983 45C 0.8542
984 5MH 0.8532
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2D09; Ligand: FLV; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2d09.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 2D09; Ligand: FLV; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2d09.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
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