-->
Receptor
PDB id Resolution Class Description Source Keywords
2C91 2.3 Å EC: 1.-.-.- MOUSE SUCCINIC SEMIALDEHYDE REDUCTASE, AKR7A5 MUS MUSCULUS ALDO/KETO REDUCTASE AKR SUCCINIC SEMIALDEHYDE REDUCTASE TGOLGI STACK NAD NADP OXIDOREDUCTASE
Ref.: CRYSTAL STRUCTURE OF MOUSE SUCCINIC SEMIALDEHYDE RE AKR7A5: STRUCTURAL BASIS FOR SUBSTRATE SPECIFICITY. BIOCHEMISTRY V. 45 1562 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:361;
A:363;
B:361;
B:362;
B:363;
C:361;
C:362;
C:363;
D:361;
D:362;
D:363;
E:361;
E:362;
E:363;
F:361;
G:362;
G:363;
G:364;
H:361;
H:362;
I:361;
I:362;
J:363;
J:364;
J:366;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
MES B:364;
C:364;
D:364;
I:363;
J:368;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
submit data
195.237 C6 H13 N O4 S C1COC...
NAP A:350;
B:350;
C:350;
D:350;
E:350;
F:350;
G:350;
H:350;
I:350;
J:350;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
743.405 C21 H28 N7 O17 P3 c1cc(...
PO4 A:364;
J:367;
Invalid;
Invalid;
none;
none;
submit data
94.971 O4 P [O-]P...
TLA A:360;
B:360;
C:360;
D:360;
E:360;
F:360;
G:360;
H:360;
I:360;
J:360;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
150.087 C4 H6 O6 [C@@H...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2C91 2.3 Å EC: 1.-.-.- MOUSE SUCCINIC SEMIALDEHYDE REDUCTASE, AKR7A5 MUS MUSCULUS ALDO/KETO REDUCTASE AKR SUCCINIC SEMIALDEHYDE REDUCTASE TGOLGI STACK NAD NADP OXIDOREDUCTASE
Ref.: CRYSTAL STRUCTURE OF MOUSE SUCCINIC SEMIALDEHYDE RE AKR7A5: STRUCTURAL BASIS FOR SUBSTRATE SPECIFICITY. BIOCHEMISTRY V. 45 1562 2006
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 318 families.
1 2C91 - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 280 families.
1 2C91 - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
2 2BP1 - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
3 1GVE - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 2C91 - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
2 2BP1 - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
3 1GVE - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NAP; Similar ligands found: 123
No: Ligand ECFP6 Tc MDL keys Tc
1 NAP 1 1
2 NA0 0.881356 0.986301
3 TAP 0.872881 0.934211
4 NDO 0.840336 0.972603
5 NAD 0.811966 0.986111
6 N01 0.733871 0.958904
7 A3D 0.712 0.972603
8 NBP 0.707692 0.935065
9 NHD 0.68254 0.958904
10 NJP 0.661417 0.972973
11 NFD 0.658915 0.934211
12 NXX 0.619048 0.959459
13 DND 0.619048 0.959459
14 AMP NAD 0.606061 0.958904
15 ZID 0.605839 0.972603
16 NAQ 0.59854 0.922078
17 ATR 0.59292 0.917808
18 NAE 0.591241 0.946667
19 NDE 0.58042 0.986301
20 A22 0.571429 0.958904
21 NAJ 0.567164 0.986111
22 A2R 0.563025 0.932432
23 NDC 0.561644 0.922078
24 NA7 0.552846 0.907895
25 ODP 0.551471 0.935065
26 A2P 0.539823 0.930556
27 8ID 0.537313 0.910256
28 NPW 0.525547 0.8875
29 NZQ 0.521739 0.910256
30 CNA 0.521739 0.959459
31 NDP 0.514493 0.922078
32 PO4 PO4 A A A A PO4 0.503937 0.930556
33 1DG 0.503401 0.922078
34 DG1 0.503401 0.922078
35 TXP 0.5 0.922078
36 NMN AMP PO4 0.492958 0.921053
37 XNP 0.492958 0.875
38 25L 0.492308 0.958904
39 25A 0.492063 0.972222
40 NMN 0.486726 0.888889
41 NGD 0.485714 0.935065
42 9JJ 0.481707 0.8875
43 2AM 0.477876 0.891892
44 ADP 0.458333 0.945205
45 PAP 0.451613 0.931507
46 A2D 0.445378 0.945205
47 AN2 0.442623 0.932432
48 7L1 0.441558 0.777778
49 ADP PO3 0.44 0.944444
50 SAP 0.44 0.896104
51 AGS 0.44 0.896104
52 M33 0.439024 0.906667
53 AR6 AR6 0.438849 0.945205
54 BA3 0.438017 0.945205
55 OAD 0.43609 0.92
56 ADP BMA 0.43609 0.92
57 DQV 0.435714 0.958904
58 HEJ 0.435484 0.945205
59 ATP 0.435484 0.945205
60 OOB 0.435115 0.958904
61 B4P 0.434426 0.945205
62 AP5 0.434426 0.945205
63 GAP 0.433071 0.92
64 0WD 0.432432 0.922078
65 2A5 0.432 0.87013
66 5FA 0.432 0.945205
67 AQP 0.432 0.945205
68 AT4 0.430894 0.907895
69 00A 0.428571 0.909091
70 DAL AMP 0.427481 0.932432
71 CA0 0.427419 0.92
72 ADP ALF 0.426357 0.871795
73 ALF ADP 0.426357 0.871795
74 9X8 0.425373 0.871795
75 ACP 0.424 0.92
76 NAJ PZO 0.423841 0.897436
77 9SN 0.423358 0.897436
78 ADP VO4 0.423077 0.932432
79 VO4 ADP 0.423077 0.932432
80 WAQ 0.422222 0.884615
81 V3L 0.421875 0.945205
82 ACQ 0.421875 0.92
83 ADQ 0.421053 0.92
84 AR6 0.420635 0.918919
85 APR 0.420635 0.918919
86 ATP A A A 0.42029 0.958333
87 CO7 0.419753 0.786517
88 3OD 0.419118 0.92
89 1ZZ 0.419118 0.841463
90 DLL 0.41791 0.958904
91 AD9 0.417323 0.92
92 NAX 0.416667 0.875
93 OVE 0.416667 0.857143
94 MYR AMP 0.416058 0.841463
95 AV2 0.415385 0.868421
96 A3P 0.414634 0.944444
97 NNR 0.414414 0.72973
98 OMR 0.413793 0.831325
99 6YZ 0.412214 0.92
100 ANP 0.410853 0.92
101 A1R 0.410448 0.860759
102 ABM 0.409836 0.893333
103 A 0.408333 0.944444
104 AMP 0.408333 0.944444
105 SON 0.408 0.933333
106 PPS 0.407692 0.829268
107 5AL 0.407692 0.932432
108 NAI 0.406897 0.909091
109 7D3 0.406504 0.857143
110 ADX 0.404762 0.829268
111 ATF 0.40458 0.907895
112 3UK 0.404412 0.945946
113 TYR AMP 0.404255 0.921053
114 AMP DBH 0.404255 0.894737
115 139 0.402685 0.875
116 50T 0.401575 0.906667
117 SRP 0.401515 0.907895
118 A A 0.40146 0.972222
119 B5V 0.40146 0.933333
120 A3R 0.4 0.860759
121 3AM 0.4 0.90411
122 B5M 0.4 0.921053
123 FA5 0.4 0.933333
Ligand no: 2; Ligand: TLA; Similar ligands found: 13
No: Ligand ECFP6 Tc MDL keys Tc
1 TAR 1 1
2 TLA 1 1
3 SRT 1 1
4 RAT 0.588235 1
5 LGT 0.588235 1
6 GAE 0.588235 1
7 LAC 0.5 0.611111
8 2OP 0.5 0.611111
9 IPM 0.47619 0.8
10 LFC 0.434783 0.777778
11 ICT 0.416667 0.727273
12 DXX 0.411765 0.777778
13 MAK 0.4 0.941176
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2C91; Ligand: NAP; Similar sites found with APoc: 136
This union binding pocket(no: 1) in the query (biounit: 2c91.bio8) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 5YJS SAL 1.47929
2 1W8S FBP 1.52091
3 3ESS 18N 1.73913
4 5A04 BGC 1.77515
5 1AMU AMP 1.77515
6 2HK9 ATR 1.77515
7 3H4Z GLC GLC 1.77515
8 5A0U CHT 1.77515
9 5EO8 TFU 1.92926
10 5N9X THR 2.07101
11 5ZA2 NXL 2.07101
12 1QPR PPC 2.11268
13 1DQX BMP 2.24719
14 1Q6O LG6 2.31481
15 4BI7 PGA 2.33463
16 3AI8 HNQ 2.34375
17 2D24 XYS XYS 2.36686
18 6CIB ADP 2.36686
19 2Q8Z NUP 2.36686
20 1QDS PGA 2.39044
21 6BVE PGA 2.44898
22 4TS1 TYR 2.50784
23 2GQS C2R 2.53165
24 5FJJ MAN 2.66272
25 4WEI GLC GAL 2.66272
26 3ITA AIC 2.95858
27 1Y4C GLC GLC 2.95858
28 4IFP MAL 2.95858
29 2F6U CIT 2.99145
30 1QH9 LAC 3.01724
31 1TRD PGH 3.2
32 5EYW PGA 3.21285
33 4IP7 FLC 3.25444
34 3UWV 2PG 3.25444
35 4FMS BDP 3.25444
36 6FA4 D1W 3.46821
37 4I9A NCN 3.47222
38 5JIL 6KL 3.5503
39 1FDJ 13P 3.5503
40 1M5W DXP 3.5503
41 2Z6I FMN 3.5503
42 6H45 QEI 3.5503
43 4JEJ 1GP 3.68852
44 5LNW HG3 3.79747
45 5LNW RP5 3.79747
46 5BJZ MAL 3.84615
47 6E1Q CFA 4.14201
48 2AL2 PEP 4.14201
49 4C2C ALA ALA ALA 4.14201
50 4KCT PYR 4.14201
51 2AL2 2PG 4.14201
52 1B4B ARG 4.22535
53 1WLJ U5P 4.2328
54 2BTM PGA 4.36508
55 4YMZ 13P 4.38247
56 5DZ2 212 4.43787
57 3HQP FDP 4.43787
58 2WHX ADP 4.43787
59 2O66 FLC 4.44444
60 3EJ0 11X 4.59184
61 2V2G BEZ 4.72103
62 5BOE PEP 4.73373
63 1SW0 PGA 4.83871
64 3B0P FMN 4.85714
65 3EXS 5RP 4.97738
66 3QTP 2PG 5.02959
67 6GW4 CHO 5.21173
68 5ZI9 FLC 5.32544
69 4K91 SIN 5.32544
70 4UTU LRY 5.32544
71 4UTW RFW 5.32544
72 3H0L ADP 5.6213
73 1DLL LAT 5.6213
74 5TVF PUT 5.88235
75 5TVM PUT 5.88235
76 2W5P CL8 6.04027
77 3CW9 AMP 6.34921
78 4USI AKG 6.49351
79 5TCI MLI 6.52174
80 1DBT U5P 6.69456
81 1PVC ILE SER GLU VAL 7.14286
82 2EW5 Y12 7.18232
83 1GPM AMP 7.2381
84 1VKF CIT 7.44681
85 2GMM MAN MAN 7.53968
86 1Q8O MAN MMA 7.53968
87 3FDZ DG2 7.98817
88 4NAE 1GP 8.44444
89 2RIF AMP 8.51064
90 6APL C5P 8.57988
91 1KPG 16A 9.05923
92 4AVV CD 9.31373
93 1KC7 PPR 9.46746
94 1MI3 NAD 9.62733
95 2HJ4 PNZ 9.62963
96 3OVR 5SP 9.64912
97 5AHN IMP 9.76331
98 5Z6T NAP 10.0592
99 3A16 PXO 10.0592
100 2YPI PGA 10.0592
101 6GVZ CHO 10.1639
102 5CSS G3P 11.0619
103 6FXR UDP 12.7219
104 1ZEI CRS 13.2075
105 1FRB ZST 13.6508
106 5AZ1 NDP 13.9053
107 4IJR NDP 14.5349
108 3CV6 HXS 14.8607
109 3CV6 NAP 14.8607
110 1NXJ TLA 15.3005
111 1MAR ZST 16.5079
112 1MAR NAP 16.5079
113 5ZCM NDP DTT 17.1598
114 3GLC R5P 18.6391
115 1AFS NAP 18.9349
116 1VP5 NAP 19.1275
117 3QDW NDG 19.5804
118 3QDY CBS 19.5804
119 1VBJ NAP 20.4142
120 3NTY 5P3 21.0059
121 3NTY NAP 21.0059
122 3CV7 C2U 23.3728
123 3CV7 NAP 23.3728
124 3CAQ NDP 23.3728
125 1ZUA NAP 23.6686
126 1ZUA TOL 23.6686
127 1EKO I84 24.2604
128 1EKO NAP 24.2604
129 3KRB NAP 24.2604
130 2WZM NA7 25.7951
131 4H8N NDP 26.0355
132 2BGS NDP 26.6272
133 1ZGD NAP 28.1065
134 1M9H NAD 29.1367
135 4JTA NAP 40.8408
136 1EXB NDP 40.9639
Pocket No.: 2; Query (leader) PDB : 2C91; Ligand: TLA; Similar sites found with APoc: 34
This union binding pocket(no: 2) in the query (biounit: 2c91.bio8) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 2VUT NAD 1.77515
2 4KWD JF2 1.91083
3 4WAS COO 2.07101
4 4WAS NAP 2.07101
5 3WDM ADN 2.29885
6 5H5A 6OU 2.5
7 3B99 U51 2.95858
8 5W19 9TD 3.25444
9 1FL2 FAD 3.54839
10 1GQG DCD 4
11 1ZDU P3A 4.08163
12 5FR0 SIZ 4.43787
13 4NSQ COA 4.43787
14 4J7Q B7N 4.5045
15 2QZO KN1 4.65116
16 1BZL GCG 4.73373
17 1OLM VTQ 5.02959
18 6FE1 V14 5.05837
19 4RSE PLM 5.91716
20 4GBD MCF 8.95197
21 1N9L FMN 14.6789
22 3CV6 NAP 14.8607
23 3CV6 HXS 14.8607
24 1VBJ CIT 20.4142
25 3NTY NAP 21.0059
26 3CV7 NAP 23.3728
27 3CV7 C2U 23.3728
28 3CAQ NDP 23.3728
29 1EKO I84 24.2604
30 1EKO NAP 24.2604
31 5ZCO PEK 31.9149
32 5Z84 PEK 31.9149
33 2DYR PEK 31.9149
34 2DYS PEK 31.9149
Pocket No.: 3; Query (leader) PDB : 2C91; Ligand: NAP; Similar sites found with APoc: 32
This union binding pocket(no: 3) in the query (biounit: 2c91.bio1) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 1C1X HFA 1.18343
2 1BW9 PPY 1.18343
3 4EIL FOL 1.47929
4 1IGW PYR 2.07101
5 5MRH Q9Z 2.36686
6 1USI PHE 2.36686
7 1WK8 VMS 2.57732
8 3OCP CMP 2.8777
9 5Z69 AGS 2.95858
10 2GJP MAL 2.95858
11 5AGR A52 3.01724
12 4KRG OPE 3.5503
13 5NNS AKR 4.44444
14 4C01 QY9 4.60993
15 4K47 WMP 4.6875
16 2ZQ0 ACR 4.73373
17 3TAO PGH 4.86891
18 4RW3 IPD 5.02959
19 3I7S PYR 5.02959
20 2AZC 3TL 5.05051
21 4OWK NGA 5.07246
22 1V7Z CRN 6.15385
23 5BXA MAN 6.50888
24 2OYH GLY HIS ARG PRO 6.80473
25 3SJK LYS PRO VAL LEU ARG THR ALA 6.84211
26 1S8G DAO 7.43802
27 1UKG MMA 7.53968
28 2J9L ATP 7.56757
29 6D5V FVY 7.78443
30 6D5M FW4 7.78443
31 6D5J FV4 7.78443
32 6D5H FV7 7.78443
Pocket No.: 4; Query (leader) PDB : 2C91; Ligand: TLA; Similar sites found with APoc: 21
This union binding pocket(no: 4) in the query (biounit: 2c91.bio1) has 9 residues
No: Leader PDB Ligand Sequence Similarity
1 2JEV NHQ 1.47929
2 1I00 UMP 1.72414
3 1I00 D16 1.72414
4 3IQE F42 1.76678
5 3IQE H4M 1.76678
6 6ESN BWE 2.62172
7 3WCA FPS 2.66272
8 5NTW 98N 2.72374
9 4JB0 ENO 2.95858
10 4I3V NAD 2.95858
11 5IH1 6BQ 2.98013
12 5IH1 GDP 2.98013
13 4TMC HBA 3.25444
14 5L9O GOP 3.73134
15 1ESM COA 5.37975
16 5DRB 5FJ 7.56014
17 1JG9 GLC 7.69231
18 2HOX P1T 9.76331
19 3LKJ LKJ 12.766
20 5KO1 6UY 14.2012
21 1Q23 FUA 15.9817
Pocket No.: 5; Query (leader) PDB : 2C91; Ligand: NAP; Similar sites found with APoc: 18
This union binding pocket(no: 5) in the query (biounit: 2c91.bio3) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 5KJW 53C 2.07101
2 4CSD MFU 3.30882
3 3HEE R5P 3.3557
4 5ECP GSH 3.58744
5 3JUC PCA 3.92157
6 5AHS SIN 4.73373
7 2FLI DX5 5
8 3UG4 AHR 5.6213
9 1WD4 AHR 5.6213
10 1DMH MCT 6.10932
11 3K0T BGC 6.29371
12 3PH4 AOS 6.50888
13 2IMG MLT 6.62252
14 6F7X MFU 7.77778
15 5N26 CPT 8.79121
16 3Q8U ADP 11.465
17 1TLG GAL 20.8
18 3KPB SAM 28.6885
Pocket No.: 6; Query (leader) PDB : 2C91; Ligand: TLA; Similar sites found with APoc: 10
This union binding pocket(no: 6) in the query (biounit: 2c91.bio3) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 3UXL CFI 1.77515
2 2Z6D FMN 4.61538
3 5AAV GW5 4.7619
4 5A8R TP7 6.50888
5 3LVW GSH 8.57988
6 1MI3 NAD 9.62733
7 6GG9 FMN 19.7531
8 1ZUA NAP 23.6686
9 1ZUA TOL 23.6686
10 3OLL EST 31.5789
Pocket No.: 7; Query (leader) PDB : 2C91; Ligand: NAP; Similar sites found with APoc: 12
This union binding pocket(no: 7) in the query (biounit: 2c91.bio5) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 1BXG HCI 1.18343
2 3EWA ANP 2.17391
3 1O5Q PYR 2.36686
4 4IAW LIZ 2.65957
5 2NW9 FT6 2.94118
6 4M7J KDA KDO KDO 3.19635
7 4Z2S NDG 4.22535
8 4Z2S NAG 4.22535
9 4ZDM GLY 5.36398
10 3LGS ADE 5.61798
11 5F7U GLC GLC 5.91716
12 3KIH GDL 10.3093
Pocket No.: 8; Query (leader) PDB : 2C91; Ligand: TLA; Similar sites found with APoc: 19
This union binding pocket(no: 8) in the query (biounit: 2c91.bio5) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 1VA6 P2S 2.12355
2 5YAK YOF 2.65152
3 4BXK 1IU 2.95858
4 4L9Z COA 2.95858
5 2V58 LZJ 3.25444
6 2WPF FAD 3.84615
7 2WPF WPF 3.84615
8 4KP7 NAP 4.73373
9 4KP7 1UQ 4.73373
10 2Z77 HE7 6.47482
11 3DVA TPW 8.57988
12 4JX1 CAM 8.57988
13 5Z6T NAP 10.0592
14 1UMP SQA 11.5385
15 1FRB ZST 13.6508
16 4IJR NDP 14.5349
17 1AFS NAP 18.9349
18 3NTY 5P3 21.0059
19 5FKP 6UL 27.2727
Pocket No.: 9; Query (leader) PDB : 2C91; Ligand: TLA; Similar sites found with APoc: 13
This union binding pocket(no: 9) in the query (biounit: 2c91.bio7) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 4EN4 ATP 1.60256
2 4EN4 GT1 1.60256
3 5F7V GLC GLC GLC GLC 1.77515
4 2HK9 NAP 1.77515
5 5JNN 6LM 2.10526
6 2YG2 S1P 2.90698
7 2QUN FUD 3.10345
8 3FAP ARD 5.60748
9 3GWT 066 5.6213
10 1OE0 TTP 6.08696
11 3W9R A8S 6.87831
12 5XWV 8H6 7.69231
13 5ZCM NDP DTT 17.1598
Pocket No.: 10; Query (leader) PDB : 2C91; Ligand: NAP; Similar sites found with APoc: 5
This union binding pocket(no: 10) in the query (biounit: 2c91.bio7) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 2QS8 MET 1.18343
2 5D4Y BXP 3.25444
3 4A59 AMP 6.21302
4 5OQW A4E 10.2362
5 3KIF GDL 10.3774
Pocket No.: 11; Query (leader) PDB : 2C91; Ligand: NAP; Similar sites found with APoc: 8
This union binding pocket(no: 11) in the query (biounit: 2c91.bio2) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 1OFZ FUC 2.36686
2 1OFZ FUL 2.36686
3 2I56 RNS 2.66272
4 3R6K FUC GAL GLA 2.95082
5 6C4A PYR 3.39367
6 2OFE NAG 4.22535
7 5LFV SIA GAL NAG 4.73373
8 3FIU AMP 4.81928
Pocket No.: 12; Query (leader) PDB : 2C91; Ligand: TLA; Similar sites found with APoc: 17
This union binding pocket(no: 12) in the query (biounit: 2c91.bio2) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 4OKZ 3E9 1.77515
2 5IXG OTP 2.95858
3 2CHN NGT 3.5503
4 5Z1N PEF 3.57143
5 5AA4 6X4 5.32544
6 6C6O ENG 5.6213
7 3N0Y APC 6.70391
8 5AZ1 NDP 13.9053
9 1VBJ NAP 20.4142
10 3KRB NAP 24.2604
11 4H8N NDP 26.0355
12 2BGS NDP 26.6272
13 1ZGD NAP 28.1065
14 1M9H NAD 29.1367
15 5E7V M7E 40
16 4JTA NAP 40.8408
17 1EXB NDP 40.9639
Pocket No.: 13; Query (leader) PDB : 2C91; Ligand: NAP; Similar sites found with APoc: 12
This union binding pocket(no: 13) in the query (biounit: 2c91.bio9) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 4JLZ UTP 1.77515
2 1X8X TYR 2.79503
3 2J5V PCA 2.95858
4 2DC1 CIT 3.38983
5 5HTX ADP 4.43787
6 4XP7 FNR 5.91716
7 2GN3 MMA 7.53968
8 3ZW2 NAG GAL FUC 11.4943
9 3CM2 X23 11.5385
10 3W9Z FMN 12.4224
11 3QMN A3P 13.9535
12 3QDX CBS 19.5804
Pocket No.: 14; Query (leader) PDB : 2C91; Ligand: TLA; Similar sites found with APoc: 1
This union binding pocket(no: 14) in the query (biounit: 2c91.bio9) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 1O6U PLM 5.02959
Pocket No.: 15; Query (leader) PDB : 2C91; Ligand: NAP; Similar sites found with APoc: 5
This union binding pocket(no: 15) in the query (biounit: 2c91.bio4) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 2GRU EXO 2.36686
2 5C9P FUC 4.14201
3 5X7Q GLC GLC 6.80473
4 3A23 GAL 7.10059
5 5C8W PCG 7.69231
Pocket No.: 16; Query (leader) PDB : 2C91; Ligand: TLA; Similar sites found with APoc: 9
This union binding pocket(no: 16) in the query (biounit: 2c91.bio4) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 6C8X BVR 1.0101
2 3MDV CL6 1.47929
3 5JE0 AZ8 2.02429
4 5JE0 SAH 2.02429
5 4F9U PBD 2.88462
6 6EKZ SNP 8.53659
7 5ZCO PGV 31.9149
8 2DYR PGV 31.9149
9 5Z84 PGV 31.9149
Pocket No.: 17; Query (leader) PDB : 2C91; Ligand: NAP; Similar sites found with APoc: 5
This union binding pocket(no: 17) in the query (biounit: 2c91.bio10) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 5THY SAH 2.95858
2 3EJW PAV 5.71429
3 3AB4 THR 6.74157
4 2PHT MAN MAN MAN 7.53968
5 4IPN 1FT 8.57988
Pocket No.: 18; Query (leader) PDB : 2C91; Ligand: TLA; Similar sites found with APoc: 1
This union binding pocket(no: 18) in the query (biounit: 2c91.bio10) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 3SQG TP7 7.8853
Pocket No.: 19; Query (leader) PDB : 2C91; Ligand: NAP; Similar sites found with APoc: 5
This union binding pocket(no: 19) in the query (biounit: 2c91.bio6) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 5EZ1 ICB 2.52708
2 5CC2 CKA 4.15094
3 2QHS OCA 5.06329
4 3VGL BGC 5.29595
5 4CMI M4V 8.33333
Pocket No.: 20; Query (leader) PDB : 2C91; Ligand: TLA; Similar sites found with APoc: 2
This union binding pocket(no: 20) in the query (biounit: 2c91.bio6) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 5NW7 9C2 2.66272
2 3U2U UDP 6.80473
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