-->
Receptor
PDB id Resolution Class Description Source Keywords
2C6Q 1.7 Å EC: 1.7.1.7 CRYSTAL STRUCTURE OF HUMAN GUANOSINE MONOPHOSPHATE REDUCTASE 2 GMPR2 IN COMPLEX WITH IMP AND NADPH HOMO SAPIENS TIM BARREL METAL-BINDING NADP OXIDOREDUCTASE POTASSIUM
Ref.: COFACTOR MOBILITY DETERMINES REACTION OUTCOME IN TH AND GMPR (BETA-ALPHA)(8) BARREL ENZYMES. NAT.CHEM.BIOL. V. 7 950 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
IMP A:1337;
B:1339;
C:1337;
D:1337;
E:1337;
F:1337;
G:1338;
H:1337;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
348.206 C10 H13 N4 O8 P c1nc2...
NDP A:1338;
B:1340;
C:1338;
D:1338;
E:1338;
F:1338;
H:1338;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
submit data
745.421 C21 H30 N7 O17 P3 c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2C6Q 1.7 Å EC: 1.7.1.7 CRYSTAL STRUCTURE OF HUMAN GUANOSINE MONOPHOSPHATE REDUCTASE 2 GMPR2 IN COMPLEX WITH IMP AND NADPH HOMO SAPIENS TIM BARREL METAL-BINDING NADP OXIDOREDUCTASE POTASSIUM
Ref.: COFACTOR MOBILITY DETERMINES REACTION OUTCOME IN TH AND GMPR (BETA-ALPHA)(8) BARREL ENZYMES. NAT.CHEM.BIOL. V. 7 950 2011
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2BZN - IMP C10 H13 N4 O8 P c1nc2c(n1[....
2 2C6Q - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2BWG - 5GP C10 H14 N5 O8 P c1nc2c(n1[....
2 2BLE - 5GP C10 H14 N5 O8 P c1nc2c(n1[....
3 2BZN - IMP C10 H13 N4 O8 P c1nc2c(n1[....
4 2C6Q - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
50% Homology Family (16)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 5MCP - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 4Z87 Ki = 210 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 5TC3 - 5GP C10 H14 N5 O8 P c1nc2c(n1[....
4 1PVN Ki = 0.15 nM MZP C9 H12 N3 O9 P c1[nH+]c(c....
5 5AHN - IMP C10 H13 N4 O8 P c1nc2c(n1[....
6 1MEW - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
7 1ME7 Ki = 65 nM RVP C8 H13 N4 O8 P c1nc(nn1[C....
8 1MEH - MOA C17 H20 O6 Cc1c2c(c(c....
9 2C6Q - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
10 4ZQP Ki = 1580 nM KP3 C28 H32 N8 O8 Cc1c2c(c(c....
11 4ZQM - XMP C10 H14 N4 O9 P c1[nH+]c2c....
12 5AHM - IMP C10 H13 N4 O8 P c1nc2c(n1[....
13 4Z0G Ki = 600 uM 5GP C10 H14 N5 O8 P c1nc2c(n1[....
14 4XTI - IMP C10 H13 N4 O8 P c1nc2c(n1[....
15 4XTD - IMP C10 H13 N4 O8 P c1nc2c(n1[....
16 5K4X ic50 = 0.38 uM 6Q9 C12 H13 N5 O2 S Cc1c(c(n[n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: IMP; Similar ligands found: 76
No: Ligand ECFP6 Tc MDL keys Tc
1 IMP 1 1
2 IDP 0.824324 0.986111
3 R7I 0.759494 0.958904
4 R5I 0.759494 0.958904
5 NOS 0.724638 0.835616
6 5GP 0.609756 0.972603
7 G 0.609756 0.972603
8 DI 0.578313 0.92
9 SIB 0.549451 0.772152
10 93A 0.523256 0.841463
11 GDP 0.505495 0.959459
12 GP3 0.494505 0.934211
13 C2R 0.493827 0.891892
14 GTP 0.489362 0.959459
15 GP2 0.48913 0.922078
16 GNH 0.483871 0.946667
17 G2P 0.479167 0.922078
18 AMZ 0.47561 0.90411
19 SNI 0.475 0.8
20 GMV 0.473684 0.934211
21 GAV 0.469388 0.922078
22 GCP 0.46875 0.934211
23 G1R 0.46875 0.946667
24 AIR 0.468354 0.888889
25 PRT 0.466019 0.972222
26 NIA 0.464286 0.835443
27 9GM 0.463918 0.934211
28 GNP 0.463918 0.934211
29 GSP 0.463918 0.910256
30 AMP 0.458824 0.90411
31 1RB 0.458824 0.847222
32 A 0.458824 0.90411
33 ALF 5GP 0.458333 0.875
34 6SW 0.456522 0.930556
35 RBZ 0.453488 0.837838
36 GPG 0.45098 0.922078
37 7RP 0.448276 0.888889
38 GKE 0.447619 0.922078
39 GDC 0.447619 0.922078
40 GDD 0.447619 0.922078
41 RMB 0.443182 0.835616
42 AAM 0.443182 0.90411
43 P2P 0.443182 0.864865
44 IMO 0.443182 0.890411
45 7RA 0.443182 0.891892
46 FAI 0.443182 0.90411
47 JLN 0.443182 0.90411
48 G2R 0.441176 0.922078
49 G7M 0.43956 0.934211
50 XMP 0.438202 0.932432
51 IRN 0.435897 0.830986
52 Y9Z 0.433962 0.865854
53 71V 0.433333 0.825
54 PMO 0.433333 0.813333
55 GDP AF3 0.431373 0.875
56 ALF GDP 0.431373 0.875
57 GDP ALF 0.431373 0.875
58 JB2 0.431193 0.922078
59 GKD 0.431193 0.922078
60 GFB 0.429907 0.922078
61 GDR 0.429907 0.922078
62 6CK 0.425926 0.898734
63 G3A 0.425926 0.934211
64 YGP 0.424528 0.8875
65 G5P 0.422018 0.934211
66 PGS 0.419355 0.825
67 GTG 0.416667 0.898734
68 RVP 0.416667 0.837838
69 GDX 0.414414 0.934211
70 GUO 0.41 0.931507
71 GMP 0.406977 0.84
72 U2G 0.405172 0.898734
73 2SA 0.40404 0.894737
74 G G 0.40367 0.934211
75 6C6 0.402062 0.846154
76 GPD 0.401786 0.8875
Ligand no: 2; Ligand: NDP; Similar ligands found: 172
No: Ligand ECFP6 Tc MDL keys Tc
1 NDP 1 1
2 0WD 0.827273 1
3 NAI 0.803738 0.986842
4 NMN AMP PO4 0.794643 0.948052
5 NPW 0.692308 0.962025
6 NZQ 0.686441 0.987013
7 1DG 0.68 1
8 DG1 0.68 1
9 A2R 0.650943 0.909091
10 A22 0.64486 0.934211
11 TXP 0.644628 0.924051
12 ATR 0.640777 0.894737
13 NA7 0.636364 0.886076
14 XNP 0.620968 0.949367
15 AP0 0.598361 0.948718
16 A2P 0.598039 0.881579
17 NJP 0.574803 0.923077
18 25L 0.550847 0.934211
19 ODP 0.550388 0.936709
20 NAX 0.544 0.949367
21 25A 0.53913 0.921053
22 80F 0.537879 0.914634
23 2AM 0.529412 0.87013
24 6V0 0.519685 0.974026
25 NAP 0.514493 0.922078
26 7L1 0.507143 0.763441
27 EAD 0.507143 0.949367
28 A2D 0.504673 0.921053
29 TXE 0.503876 0.935897
30 NA0 0.496454 0.910256
31 TXD 0.496124 0.911392
32 SAP 0.495575 0.875
33 AGS 0.495575 0.875
34 P1H 0.493056 0.925926
35 CO7 0.489796 0.791209
36 TAP 0.489362 0.864198
37 PAP 0.482456 0.907895
38 BA3 0.481818 0.921053
39 NAJ PZO 0.478261 0.924051
40 ATP 0.477876 0.921053
41 HEJ 0.477876 0.921053
42 B4P 0.477477 0.921053
43 AP5 0.477477 0.921053
44 ADP 0.477477 0.921053
45 OAD 0.47541 0.897436
46 AR6 0.473684 0.896104
47 AQP 0.473684 0.921053
48 5FA 0.473684 0.921053
49 APR 0.473684 0.896104
50 AN2 0.473214 0.909091
51 3OD 0.467742 0.897436
52 50T 0.464912 0.884615
53 NAJ PYZ 0.464789 0.879518
54 9X8 0.463415 0.851852
55 PO4 PO4 A A A A PO4 0.463415 0.857143
56 V3L 0.461538 0.896104
57 2A5 0.46087 0.85
58 AT4 0.460177 0.886076
59 A1R 0.459016 0.841463
60 4AD 0.459016 0.875
61 ADQ 0.459016 0.897436
62 OVE 0.458716 0.8375
63 OMR 0.458647 0.813953
64 PPS 0.457627 0.811765
65 AD9 0.456897 0.897436
66 CA0 0.45614 0.897436
67 M33 0.45614 0.884615
68 ADJ 0.455882 0.879518
69 A3P 0.455357 0.894737
70 ACP 0.452174 0.897436
71 ENP 0.451613 0.85
72 UP5 0.451128 0.948052
73 SRP 0.45 0.8625
74 ANP 0.449153 0.897436
75 ACQ 0.449153 0.897436
76 PRX 0.448276 0.82716
77 A3R 0.447154 0.841463
78 5AL 0.445378 0.884615
79 7D4 0.443478 0.8375
80 ADX 0.443478 0.811765
81 6YZ 0.438017 0.897436
82 A 0.436364 0.894737
83 AMP 0.436364 0.894737
84 4TC 0.433824 0.924051
85 7D3 0.433628 0.8375
86 DCA 0.433566 0.788889
87 ETB 0.433566 0.797753
88 BIS 0.433071 0.864198
89 1ZZ 0.433071 0.802326
90 00A 0.432 0.864198
91 ATF 0.429752 0.886076
92 DQV 0.428571 0.934211
93 0T1 0.427586 0.788889
94 5SV 0.427419 0.788235
95 8QN 0.427419 0.884615
96 3AM 0.427273 0.857143
97 N01 0.426573 0.884615
98 PR8 0.425197 0.811765
99 LAD 0.425197 0.821429
100 WAQ 0.425197 0.841463
101 DTP 0.425 0.8375
102 AMO 0.424 0.886076
103 PAJ 0.424 0.843373
104 APC 0.423729 0.886076
105 UPA 0.423358 0.935897
106 48N 0.422222 0.853659
107 FYA 0.421875 0.860759
108 PTJ 0.421875 0.853659
109 CNA 0.421429 0.910256
110 PUA 0.42069 0.9125
111 DND 0.419118 0.910256
112 NXX 0.419118 0.910256
113 AV2 0.418033 0.848101
114 COA 0.417808 0.788889
115 3UK 0.417323 0.897436
116 OOB 0.416 0.909091
117 IVC 0.415584 0.78022
118 DAT 0.415254 0.8375
119 NDO 0.414966 0.897436
120 139 0.414286 0.901235
121 B5V 0.414062 0.886076
122 T99 0.413223 0.886076
123 TAT 0.413223 0.886076
124 3AT 0.413223 0.896104
125 YLB 0.413043 0.784091
126 62F 0.4125 0.823529
127 ABM 0.412281 0.848101
128 B5M 0.412214 0.875
129 YAP 0.412214 0.875
130 YLP 0.411765 0.784091
131 NB8 0.410853 0.853659
132 ME8 0.410853 0.802326
133 SON 0.410256 0.886076
134 DLL 0.409449 0.909091
135 AHX 0.409449 0.853659
136 CAO 0.409396 0.763441
137 30N 0.409396 0.72449
138 AMX 0.409396 0.797753
139 COS 0.409396 0.771739
140 7D5 0.409091 0.8125
141 4UW 0.408759 0.9125
142 F2R 0.408451 0.825581
143 APX 0.407692 0.841463
144 SRA 0.40708 0.85
145 CMX 0.406667 0.788889
146 SCO 0.406667 0.788889
147 TYM 0.405797 0.886076
148 COD 0.405594 0.777778
149 CA6 0.405229 0.70297
150 OXK 0.405229 0.771739
151 AP2 0.405172 0.886076
152 A12 0.405172 0.886076
153 9SN 0.40458 0.853659
154 LAQ 0.404412 0.802326
155 T5A 0.404255 0.914634
156 FAM 0.403974 0.771739
157 ACO 0.403974 0.763441
158 FCX 0.403974 0.763441
159 VO4 ADP 0.403226 0.860759
160 ADP VO4 0.403226 0.860759
161 YLC 0.402878 0.823529
162 1VU 0.402597 0.763441
163 B5Y 0.401515 0.875
164 FA5 0.401515 0.886076
165 HAX 0.401316 0.771739
166 AR6 AR6 0.4 0.871795
167 CAJ 0.4 0.771739
168 AFH 0.4 0.843373
169 APU 0.4 0.923077
170 A U 0.4 0.898734
171 TXA 0.4 0.886076
172 4UU 0.4 0.948052
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2C6Q; Ligand: NDP; Similar sites found with APoc: 239
This union binding pocket(no: 1) in the query (biounit: 2c6q.bio1) has 43 residues
No: Leader PDB Ligand Sequence Similarity
1 3KIH GDL None
2 1UI0 URA None
3 1QDS PGA 1.19522
4 3GLC R5P 1.35593
5 5GJO PLP 1.4245
6 4CSD MFU 1.47059
7 2WLT ASP 1.50602
8 3FXU TSU 1.63934
9 5DNC ASN 1.7094
10 3OBT SLB 1.7094
11 5XH2 NPO 1.9084
12 2AWN ADP 1.9943
13 4L9Z OXL 2.0649
14 1V9A SAH 2.09205
15 5NXX 3Q7 2.23881
16 4K79 GAL A2G 2.27273
17 2Q3O FMN 2.2792
18 2VD9 IN5 2.2792
19 2VD9 EPC 2.2792
20 3B0P FMN 2.28571
21 1G6H ADP 2.33463
22 2IV3 UDP 2.33918
23 3W9Z FMN 2.48447
24 1TL2 NDG 2.54237
25 2Q3R FMN 2.5641
26 1D8C GLV 2.5641
27 5XVS UDP 2.5641
28 4KBF AMP 2.5641
29 2HSA FMN 2.5641
30 1P7T PYR 2.5641
31 2OO0 PLP 2.5641
32 3TAO PGH 2.62172
33 3EXS 5RP 2.71493
34 1FDJ 2FP 2.849
35 1FDJ 13P 2.849
36 4UBS DIF 2.849
37 1V8B ADN 2.849
38 4GYI ADP 2.849
39 2V67 CAP 2.85714
40 2V68 CAP 2.85714
41 2V6A CAP 2.85714
42 2V63 CAP 2.85714
43 2VDH CAP 2.85714
44 1IR2 CAP 2.85714
45 2Y88 2ER 2.86885
46 4L8F MTX 2.88462
47 3TTM PUT 2.89017
48 5ZBL AMP 2.95567
49 1F76 FMN 2.97619
50 4KBA 1QM 3.02115
51 1JCM 137 3.0888
52 6BKA FMN 3.1339
53 4Q4K FMN 3.1339
54 4XFR CIT 3.1339
55 4ZM4 PLP 3.1339
56 4JIQ 1L5 3.1339
57 4JIQ FMN 3.1339
58 4YJK URA 3.1746
59 1US5 GLU 3.18471
60 4GLW NMN 3.27869
61 4UAP NGA 3.28947
62 2CUN 3PG 3.4188
63 1RBL CAP 3.4188
64 4NOS ITU 3.4188
65 2F2H XTG 3.4188
66 3GFS FMN 3.44828
67 4XP7 FNR 3.46821
68 1R0X ATP 3.4965
69 3AJ4 SEP 3.57143
70 1LYX PGA 3.62903
71 1EIX BMQ 3.67347
72 6CUZ FEV 3.7037
73 5VLQ ANP 3.7037
74 1TV5 FMN 3.7037
75 6F3M ADN 3.7037
76 1TB3 FMN 3.7037
77 4PPF FLC 3.71429
78 6HKE MLT 3.77358
79 2QCD U5P 3.84615
80 5K4G ASP 3.93939
81 2OG2 MLI 3.9886
82 3CV2 OXL 3.9886
83 5OCS FMN 3.9886
84 1ICP FMN 3.9886
85 1PJS SAH 3.9886
86 4BGB ADP 4
87 1ORR CDP 4.03458
88 1UJP CIT 4.05904
89 1IR1 CAP 4.06504
90 3QH2 3NM 4.0724
91 1M5W DXP 4.11523
92 3TTN SPD 4.11765
93 3A8T ATP 4.12979
94 1W8S FBP 4.18251
95 1Y2W NAG 4.22535
96 1QPR PPC 4.22535
97 3QPB URA 4.25532
98 2VL1 GLY GLY 4.2735
99 3RMK BML 4.2735
100 1ZGS XMM 4.2735
101 1KBI FMN 4.2735
102 1G2O IMH 4.2735
103 2BTM PGA 4.36508
104 2AOU CQA 4.45205
105 1UZD CAP 4.47761
106 6BVE PGA 4.4898
107 5MZN ADP 4.5584
108 3B9Q MLI 4.63576
109 4D79 ATP 4.71014
110 4TMC FMN 4.71464
111 3I7S PYR 4.79452
112 1TRD PGH 4.8
113 3IWD M2T 4.83871
114 2J5V PCA 4.8433
115 2GK6 ADP 4.8433
116 1LBF 137 4.8583
117 3F81 STT 4.91803
118 5ZI9 FLC 5
119 1DBT U5P 5.02092
120 1KBJ FMN 5.09709
121 2Z6J FMN 5.12048
122 2Z6I FMN 5.12821
123 4I9A NCN 5.12821
124 4A3U FMN 5.12821
125 2A19 ANP 5.14286
126 5EYW PGA 5.22088
127 3IP8 B85 5.24194
128 5E58 CPZ 5.41311
129 2HIM ASN 5.41311
130 2ZRU FMN 5.41311
131 1UH4 GLC 5.41311
132 4U36 TNR 5.41667
133 6EK3 OUL 5.42986
134 3OIX FMN 5.50725
135 1A99 PUT 5.52326
136 3ENV ABF 5.53191
137 2JK0 ASP 5.53846
138 3ITJ CIT 5.6213
139 3WXO NIZ 5.69801
140 6BFG FMN 5.69801
141 3ATY FMN 5.69801
142 5GVH FMN 5.73248
143 4WZH FMN 5.76369
144 3MJY IJZ 5.78035
145 3MJY FMN 5.78035
146 2GJN FMN 5.79268
147 2GJN NIS 5.79268
148 2BES RES 5.81395
149 5IFS ADP 5.90717
150 5CSS G3P 5.98291
151 3HYW DCQ 5.98291
152 2WW4 ADP 6.00707
153 4GQY AMP 6.06061
154 2AJH MET 6.12245
155 1C3M MAN MAN 6.12245
156 3UWV 2PG 6.13027
157 3QMN A3P 6.20155
158 1NX4 AKG 6.22711
159 5C2N NAG 6.25
160 4RDH AMP 6.25
161 4RDI ATP 6.25
162 5TCI MLI 6.26781
163 1RZM E4P 6.26781
164 2VQD AP2 6.26781
165 5H62 UDP 6.32184
166 3G2O SAM 6.35452
167 3BF1 PAU 6.4257
168 1SW0 PGA 6.45161
169 5XQL C2E 6.52921
170 4R8L ASP 6.55271
171 1CT9 AMP 6.55271
172 4JEJ 1GP 6.55738
173 4P5E N6P 6.57895
174 5WLB GNP 6.62651
175 4FAI PBD 6.66667
176 4BI7 PGA 7.00389
177 2P39 SCR 7.09677
178 4QNW FMN 7.12251
179 3GD8 GOL 7.17489
180 1GVF PGH 7.34266
181 3C3N FMN 7.37179
182 1AL8 FMN 7.40741
183 4UTU LRY 7.42358
184 4UTW RFW 7.42358
185 2X65 M1P 7.44048
186 1VKF CIT 7.44681
187 4YMU ATP 7.5
188 2QJT AMP 7.69231
189 4HKP 16B 7.69231
190 6DVH FMN 7.69231
191 4USI AKG 7.79221
192 3N9R TD3 7.81759
193 1XX6 ADP 7.8534
194 2CHT TSA 7.87402
195 1Z44 FMN 7.98817
196 1Z48 FMN 7.98817
197 1Z41 FMN 7.98817
198 1Z42 FMN 7.98817
199 5NM7 GLY 8.27068
200 5LX9 OLB 8.4507
201 4Z2S NAG 8.4507
202 4Z2S NDG 8.4507
203 2OFE NAG 8.4507
204 2CE7 ADP 8.54701
205 5JVB 2PO 8.57143
206 4M5P FMN 8.83191
207 3OVR 5SP 9.21053
208 5N9Z CAP 9.35252
209 5OYA CAP 9.35252
210 4CW5 FMN 9.40171
211 5KXE 6Y2 9.46502
212 2FJK 13P 9.83607
213 1UZH CAP 9.83607
214 5A5W GUO 9.88142
215 2VAR KDF 9.90415
216 2VAR KDG 9.90415
217 2F6U CIT 10.2564
218 1OX5 1PR 10.2564
219 6BSW UDP 10.9467
220 3BW2 FMN 11.1111
221 2D2F ADP 11.2
222 1RTW MP5 11.3636
223 4WOH 4NP 11.4458
224 4EWN 0VR 11.4625
225 3AJM 4IP 11.7371
226 1Q6O LG6 12.037
227 4YMZ 13P 13.1474
228 3AXK NDP 13.1783
229 1WDD CAP 13.2812
230 2TPS TPS 13.6564
231 2YPI PGA 15.7895
232 2FLI DX5 17.7273
233 3LEK BCW 19.6078
234 4FCW ADP 19.6141
235 4NAE 1GP 20
236 4AF0 IMP 34.4729
237 4AF0 MOA 34.4729
238 1ME8 RVP 35.3276
239 1ZFJ IMP 36.7521
Pocket No.: 2; Query (leader) PDB : 2C6Q; Ligand: NDP; Similar sites found with APoc: 174
This union binding pocket(no: 2) in the query (biounit: 2c6q.bio1) has 42 residues
No: Leader PDB Ligand Sequence Similarity
1 1WUW TSU None
2 1V3S ATP None
3 1VFS DCS 0.854701
4 1DQX BMP 1.1236
5 3VOT ADP 1.4245
6 6G1O GLV 1.7094
7 4US3 TRP 1.7094
8 3B8I OXL 1.74216
9 4FRZ ADP 1.9943
10 3HNC TTP 1.9943
11 6MJF SAH 1.9943
12 2DW7 SRT 1.9943
13 2CYC TYR 1.9943
14 4OUC 5ID 1.9943
15 3C8F MT2 2.04082
16 3RK0 AMP 2.1097
17 3RK1 ATP 2.1097
18 6CAM BGC 2.2792
19 5WP5 SAH 2.2792
20 1F9V ADP 2.30548
21 3A4M ADP 2.30769
22 4Y8D 49J 2.35294
23 2G37 FAD 2.44648
24 3V1S 0LH 2.48447
25 2IS6 ADP 2.5641
26 1T9D PYD 2.5641
27 3OTH TYD 2.5641
28 4PIV 2W4 2.5641
29 2TOH HBI 2.62391
30 5ORG 6DB 2.6616
31 2NUN ADP 2.78638
32 3UYW TAU 2.80374
33 3LDW ZOL 2.849
34 3LRE ADP 2.849
35 1GK8 CAP 2.85714
36 5M42 FMN 2.86738
37 5N6N SUC 2.91667
38 1RPN GDP 2.98507
39 3ROE THM 3.01887
40 1V59 NAD 3.1339
41 5WS9 OXL 3.1339
42 4XG0 CIT 3.1339
43 2WME NAP 3.1339
44 4AIA ADK 3.19149
45 4NZ6 DGL 3.19489
46 1VHT BA3 3.21101
47 2VT3 ATP 3.25581
48 4CUB GAL NAG 3.27869
49 1ZRH A3P 3.28467
50 1ION ADP 3.29218
51 1AQU A3P 3.367
52 2PEL LBT 3.38983
53 3HQP OXL 3.4188
54 4KCT PYR 3.4188
55 1U1J MET 3.4188
56 1ZOT EMA 3.4188
57 4TR9 ASP TRP ASN 3.4188
58 4B3J COA 3.4188
59 1QFT HSM 3.42857
60 2QUN FUD 3.44828
61 1OFZ FUC 3.52564
62 1OFZ FUL 3.52564
63 5JH2 A2P 3.54839
64 1CM0 COA 3.57143
65 4AVB CMP 3.6036
66 1R6B ADP 3.7037
67 6AM8 TRP 3.7037
68 4LUT DCS 3.7037
69 5U83 ZN8 3.77358
70 4WZ6 ATP 3.7931
71 1VAY AZA 3.83275
72 5F90 GLA GAL 3.84615
73 1TIQ COA 3.88889
74 2P3V SRT 3.90625
75 5XFI NAG NAG BMA MAN MAN NAG GAL NAG 3.92157
76 2PYY GLU 3.94737
77 2D24 XYS XYS 3.9886
78 2ZJ5 ADP 3.9886
79 1PMO PLR 3.9886
80 4IDT T28 3.9886
81 4UXL 5P8 4.03727
82 4O1P ANP 4.2735
83 1OKE BOG 4.2735
84 2Z7R STU 4.2735
85 3LM9 ADP 4.30464
86 2ZE3 AKG 4.36364
87 4M3P HCS 4.5584
88 3B1Q NOS 4.60123
89 2CH5 NDG 4.61095
90 2CH5 NAG 4.61095
91 2XT3 ADP 4.65116
92 3RE4 TO1 4.65116
93 1QD0 RR6 4.6875
94 2HK9 SKM 4.72727
95 3E5P PPI 4.8433
96 1YQT ADP 4.8433
97 5N9X THR 4.8433
98 2QK4 ATP 4.8433
99 2VWT PYR 4.86891
100 4DZ1 DAL 5.01931
101 3AB4 THR 5.05618
102 4JX1 CAH 5.30973
103 5YV5 ADP 5.41311
104 5EEH P9P 5.41311
105 4EYG VNL 5.43478
106 3QXV MTX 5.55556
107 4BWL MN9 5.69801
108 1Z0A GDP 5.74713
109 5LWY OLB 5.88235
110 6BYF CIT 5.88235
111 2CBZ ATP 5.90717
112 4B98 PXG 5.98291
113 4CNK MEU 5.98291
114 3KRL KRL 6.26866
115 6FA4 D1W 6.35838
116 5KZD RCJ 6.48464
117 3O03 GCO 6.52921
118 3W6X HZP 6.55022
119 1MFA GLA MMA ABE 6.66667
120 2PEZ DAT 6.70391
121 1FMB HYB 6.73077
122 4U00 ADP 6.96721
123 3H22 B53 7.07071
124 4M1U A2G MBG 7.14286
125 1I06 TZL 7.22222
126 2BYC FMN 7.29927
127 1F52 ADP 7.40741
128 5XNC N4P 7.40741
129 2JCB ADP 7.5
130 2J8R MSL 7.55814
131 3W54 RNB 7.59878
132 1GAW FAD 7.64331
133 5KDO GDP 7.64706
134 3BIB PSF 7.75862
135 1DMH MCT 8.03859
136 2IOR ADP 8.08511
137 2CJU PHX 8.26446
138 3LCC SAH 8.51064
139 5O74 GDP 8.62944
140 1DCP HBI 8.65385
141 1XG4 ICT 8.81356
142 3KAP FMN 8.84354
143 3LST SAH 9.11681
144 1BXG HCI 9.11681
145 1C1D PHE 9.11681
146 5WHU SIA 9.39597
147 5WHU SIA GAL GLC 9.39597
148 1BWV CAP 9.42029
149 3CTL S6P 9.52381
150 2XG5 EC5 9.63303
151 2XG5 EC2 9.63303
152 5M45 AMP 9.68661
153 3VKC FPQ 9.79021
154 2C3W GLC GLC GLC GLC 9.80392
155 3NZ1 3NY 10.3448
156 3TVQ DQH 10.6509
157 2C3H GLC GLC 11.2245
158 5DYO FLU 11.4679
159 5T52 NGA 11.5702
160 5T52 A2G 11.5702
161 2RJH DCS 11.6809
162 4M4K GDU 11.8467
163 4M4K XYP XYP 11.8467
164 5MST FUM 12.5356
165 1NXJ TLA 12.5683
166 5IFK HPA 12.8205
167 1C5C TK4 13.5514
168 3JUC PCA 13.7255
169 2DKD NG1 13.9601
170 4LO2 GAL BGC 14.1892
171 3ZKN WZV 16.055
172 2Y5S 78H 19.3878
173 2H88 TEO 20.7143
174 1KNM LAT 20.7692
Pocket No.: 3; Query (leader) PDB : 2C6Q; Ligand: NDP; Similar sites found with APoc: 26
This union binding pocket(no: 3) in the query (biounit: 2c6q.bio1) has 43 residues
No: Leader PDB Ligand Sequence Similarity
1 4IA6 EIC 1.7094
2 2OEM 1AE 1.9943
3 1VBO MAN MAN MAN 2.01342
4 2WD7 VGD 2.23881
5 4AMV F6R 2.2792
6 5A9A UTP 2.46914
7 4ZTE 4RL 2.8436
8 5MB4 NDG 2.849
9 6HL7 CP 3.44828
10 2F57 23D 3.47003
11 2IZ1 ATR 3.7037
12 2NLI FMN 4.2735
13 2NLI LAC 4.2735
14 4L80 OXL 4.31034
15 1I7M CG 4.47761
16 1G7C 5GP 5.12821
17 3K56 IS3 5.26316
18 1Z0F GDP 5.58659
19 5XCZ GLC BGC 5.69801
20 2OFW ADX 5.76923
21 1VYP TNF 6.55271
22 5VOP C2F 7.77027
23 2OFD NGA 8.4507
24 4AZ3 S35 9.03226
25 2QQC AG2 16.9811
26 5E5U MLI 17.0854
Pocket No.: 4; Query (leader) PDB : 2C6Q; Ligand: IMP; Similar sites found with APoc: 240
This union binding pocket(no: 4) in the query (biounit: 2c6q.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 3KIH GDL None
2 1QDS PGA 1.19522
3 3GLC R5P 1.35593
4 5GJO PLP 1.4245
5 3FXU TSU 1.63934
6 6G1O GLV 1.7094
7 5XH2 NPO 1.9084
8 4FRZ ADP 1.9943
9 2AWN ADP 1.9943
10 4LHD GLY 1.9943
11 4LYA ATP 1.9943
12 2OEM 1AE 1.9943
13 4L9Z OXL 2.0649
14 2Q3O FMN 2.2792
15 3B0P FMN 2.28571
16 3IB1 IMN 2.31884
17 2FKA BEF 2.32558
18 3W9Z FMN 2.48447
19 4D52 GXL 2.53968
20 4D52 GIV 2.53968
21 1TL2 NDG 2.54237
22 1D8C GLV 2.5641
23 2HSA FMN 2.5641
24 1P7T PYR 2.5641
25 2Q3R FMN 2.5641
26 2OO0 PLP 2.5641
27 5FPE 3TR 2.5641
28 6AR9 3L4 2.57353
29 1T5C ADP 2.5788
30 3TAO PGH 2.62172
31 3EXS 5RP 2.71493
32 1FDJ 13P 2.849
33 4UBS DIF 2.849
34 3LRE ADP 2.849
35 2V67 CAP 2.85714
36 2VDH CAP 2.85714
37 2V63 CAP 2.85714
38 2V68 CAP 2.85714
39 1IR2 CAP 2.85714
40 2V6A CAP 2.85714
41 2Y88 2ER 2.86885
42 4L8F MTX 2.88462
43 5N6N SUC 2.91667
44 5ZBL AMP 2.95567
45 4KBA 1QM 3.02115
46 1JCM 137 3.0888
47 1T3D CYS 3.11419
48 4Q4K FMN 3.1339
49 6BKA FMN 3.1339
50 4XFR CIT 3.1339
51 4ZM4 PLP 3.1339
52 2BO4 FLC 3.1339
53 1US5 GLU 3.18471
54 4IGH FMN 3.4188
55 4IGH 1EA 3.4188
56 4IGH ORO 3.4188
57 6AMI TRP 3.4188
58 1RBL CAP 3.4188
59 1UUO FMN 3.4188
60 1UUO BRF 3.4188
61 1UUO ORO 3.4188
62 1R0X ATP 3.4965
63 1OFZ FUL 3.52564
64 3AJ4 SEP 3.57143
65 1LYX PGA 3.62903
66 1TV5 FMN 3.7037
67 6AM8 PLT 3.7037
68 4PPF FLC 3.71429
69 6HKE LMR 3.77358
70 5U83 ZN8 3.77358
71 4PTN GXV 3.79009
72 4WZ6 ATP 3.7931
73 1VAY AZA 3.83275
74 2OG2 MLI 3.9886
75 1JQN DCO 3.9886
76 5OCS FMN 3.9886
77 2O1O RIS 3.9886
78 1ICP FMN 3.9886
79 4BGB ADP 4
80 1UJP CIT 4.05904
81 3QH2 3NM 4.0724
82 1M5W DXP 4.11523
83 3A8T ATP 4.12979
84 5Z3I ADE 4.15094
85 1W8S FBP 4.18251
86 1Y2W NAG 4.22535
87 4ORM 2V6 4.2394
88 4ORM ORO 4.2394
89 4ORM FMN 4.2394
90 3QPB URA 4.25532
91 2VL1 GLY GLY 4.2735
92 4L80 OXL 4.31034
93 3CV6 HXS 4.33437
94 3CV6 NAP 4.33437
95 2BTM PGA 4.36508
96 1UZD CAP 4.47761
97 6BVE PGA 4.4898
98 3CH6 NAP 4.54545
99 3CH6 311 4.54545
100 5MZN ADP 4.5584
101 4M3P HCS 4.5584
102 5O5Y GLC 4.5584
103 1YRB GDP 4.58015
104 3B9Q MLI 4.63576
105 1QD0 RR6 4.6875
106 3I7S PYR 4.79452
107 1TRD PGH 4.8
108 3IWD M2T 4.83871
109 3E5P PPI 4.8433
110 2J5V PCA 4.8433
111 2GK6 ADP 4.8433
112 1YQT ADP 4.8433
113 5N9X THR 4.8433
114 1JJV ATP 4.85437
115 1LBF 137 4.8583
116 2BD0 BIO 4.91803
117 5ZI9 FLC 5
118 1JJ7 ADP 5
119 4Q9N 0WE 5.03356
120 1GOJ ADP 5.07042
121 2Z6J FMN 5.12048
122 2Z6I FMN 5.12821
123 4I9A NCN 5.12821
124 5TE1 7A2 5.12821
125 5EYW PGA 5.22088
126 3IP8 B85 5.24194
127 1RDL MMA 5.30973
128 5HJQ I3P 5.41311
129 5YV5 ADP 5.41311
130 2HIM ASN 5.41311
131 2I4O ATP 5.41311
132 5E58 CPZ 5.41311
133 4KBB BGC GAL SIA NGA GAL SIA 5.41311
134 2ZRU FMN 5.41311
135 4U36 TNR 5.41667
136 6EK3 OUL 5.42986
137 3OIX FMN 5.50725
138 2JK0 ASP 5.53846
139 3ITJ CIT 5.6213
140 5XFV FMN 5.68862
141 4BWL MN9 5.69801
142 5ZXD ATP 5.69801
143 3CQ5 PMP 5.69801
144 5GVH FMN 5.73248
145 4WZH FMN 5.76369
146 2OFW ADX 5.76923
147 3MJY IJZ 5.78035
148 3MJY FMN 5.78035
149 2GJN NIS 5.79268
150 2GJN FMN 5.79268
151 6BYF CIT 5.88235
152 2CBZ ATP 5.90717
153 5CSS G3P 5.98291
154 2AJH MET 6.12245
155 3UWV 2PG 6.13027
156 3QMN A3P 6.20155
157 3E4O SIN 6.22951
158 4RDH AMP 6.25
159 4RDI ATP 6.25
160 5C2N NAG 6.25
161 5TCI MLI 6.26781
162 3G2O SAM 6.35452
163 3BF1 PAU 6.4257
164 1SW0 PGA 6.45161
165 1EP2 ORO 6.51341
166 5XQL C2E 6.52921
167 5M36 9SZ 6.55022
168 1CT9 AMP 6.55271
169 4R8L ASP 6.55271
170 3KDN CAP 6.55271
171 4JEJ 1GP 6.55738
172 5WLB GNP 6.62651
173 2PEZ DAT 6.70391
174 4IF4 BEF 6.73077
175 2WPF FAD 6.83761
176 4BI7 PGA 7.00389
177 2P39 SCR 7.09677
178 4QNW FMN 7.12251
179 1XPJ TLA 7.14286
180 3GD8 GOL 7.17489
181 4GKY MAN 7.27969
182 1GVF PGH 7.34266
183 3C3N FMN 7.37179
184 1F52 ADP 7.40741
185 4UTU LRY 7.42358
186 4UTW RFW 7.42358
187 1VKF CIT 7.44681
188 2BVE PH5 7.56302
189 2QJT AMP 7.69231
190 4USI AKG 7.79221
191 1OFD FMN 7.97721
192 3BC9 ACR 7.97721
193 1OFD AKG 7.97721
194 1Z44 FMN 7.98817
195 1Z48 FMN 7.98817
196 1Z41 FMN 7.98817
197 4CIB 7UZ 8.26211
198 5NM7 GLY 8.27068
199 2GNB MAN 8.33333
200 2OFD NGA 8.4507
201 2OFE NAG 8.4507
202 4Z2S NAG 8.4507
203 4Z2S NDG 8.4507
204 4AG9 COA 8.48485
205 5JVB 2PO 8.57143
206 3KVY URA 9.06149
207 3OVR 5SP 9.21053
208 5N9Z CAP 9.35252
209 5OYA CAP 9.35252
210 5WHU SIA 9.39597
211 5KXE 6Y2 9.46502
212 6GNO XDI 9.62963
213 5BOE PEP 9.68661
214 2FJK 13P 9.83607
215 1UZH CAP 9.83607
216 5A5W GUO 9.88142
217 1OVD ORO 9.96785
218 1OVD FMN 9.96785
219 2PYU IMP 10.0457
220 2F6U CIT 10.2564
221 1CX9 NHP 10.2564
222 1OX5 1PR 10.2564
223 6BSW UDP 10.9467
224 3BW2 FMN 11.1111
225 2WHX ADP 11.396
226 4EWN 0VR 11.4625
227 5DYO FLU 11.4679
228 1Q6O LG6 12.037
229 5IFK HPA 12.8205
230 4YMZ 13P 13.1474
231 3AXK NDP 13.1783
232 1WDD CAP 13.2812
233 2YPI PGA 15.7895
234 2QQC AG2 16.9811
235 5E5U MLI 17.0854
236 2FLI DX5 17.7273
237 4NAE 1GP 20
238 4AF0 IMP 34.4729
239 1ME8 RVP 35.3276
240 1ZFJ IMP 36.7521
Pocket No.: 5; Query (leader) PDB : 2C6Q; Ligand: IMP; Similar sites found with APoc: 53
This union binding pocket(no: 5) in the query (biounit: 2c6q.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 1WUW TSU None
2 5DNC ASN 1.7094
3 2VD9 IN5 2.2792
4 2VD9 EPC 2.2792
5 6B8O PSF 2.36686
6 4O48 ASP 2.5641
7 4B4U NAP 2.64026
8 2X7I CIT 2.92208
9 3TK1 GDP 3.0303
10 2ZX2 RAM 3.07692
11 5N53 8NB 3.07692
12 4YJK URA 3.1746
13 6EQS BV8 3.27273
14 4UAP NGA 3.28947
15 2CUN 3PG 3.4188
16 3FJG 3PG 3.58566
17 4RDN 6MD 3.59281
18 4CCW VKC 3.67893
19 2IZ1 ATR 3.7037
20 1GTE FMN 3.7037
21 1GTE IUR 3.7037
22 5A1S FLC 3.9886
23 3CV2 OXL 3.9886
24 5OD2 GLC 3.9886
25 2JBH 5GP 4
26 4AG5 ADP 4.2735
27 1G7C 5GP 5.12821
28 2WPB ZZI 5.41311
29 1A99 PUT 5.52326
30 1Z0F GDP 5.58659
31 1D4D SIN 5.69801
32 4OSP 2V4 5.70342
33 4B98 PXG 5.98291
34 2WW4 ADP 6.00707
35 5Y80 IRE 6.08108
36 1C3M MAN MAN 6.12245
37 3QVP FAD 6.26781
38 2JE7 XMM 6.27615
39 4A34 FUL 6.80272
40 5URY PAM 6.84932
41 3U7Q HCA 7.40741
42 1GXU 2HP 8.79121
43 1UA4 BGC 8.83191
44 1UA4 GLC 8.83191
45 1S16 ANP 9.68661
46 4FBL SPD 10.3203
47 3QDU CBS CBS 10.4895
48 4ETZ C2E 12.7946
49 3ESS 18N 13.913
50 1N13 AG2 17.3077
51 2W58 ADP 17.3267
52 3BY8 MLT 19.0141
53 4AF0 MOA 34.4729
Pocket No.: 6; Query (leader) PDB : 2C6Q; Ligand: IMP; Similar sites found with APoc: 27
This union binding pocket(no: 6) in the query (biounit: 2c6q.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 4GN8 ASO 1.67224
2 4WBD CIT 1.7094
3 3COB ADP 1.9943
4 4K79 GAL A2G 2.27273
5 2NZ2 ASP 2.2792
6 4Y8D 49J 2.35294
7 1MO9 KPC 2.5641
8 2F57 23D 3.47003
9 6HKE MLT 3.77358
10 5K4G ASP 3.93939
11 3WLV AZA 4.48718
12 5G6U TRP 5.36398
13 2J9L ATP 5.40541
14 1UH4 GLC 5.41311
15 5O0J GLC 5.69801
16 1QH8 HCA 6.26781
17 4P5E N6P 6.57895
18 2X65 M1P 7.44048
19 3N9R TD3 7.81759
20 1XX6 ADP 7.8534
21 2GNM MAN 8.33333
22 2GMP NAG MAN 8.33333
23 6F3G CJN 9.15254
24 5WHU SIA GAL GLC 9.39597
25 4WOH 4NP 11.4458
26 4F8L AES 14.4828
27 2V7Q ADP 18
Pocket No.: 7; Query (leader) PDB : 2C6Q; Ligand: NDP; Similar sites found with APoc: 76
This union binding pocket(no: 7) in the query (biounit: 2c6q.bio1) has 43 residues
No: Leader PDB Ligand Sequence Similarity
1 6F7X MFU None
2 4GN8 ASO 1.67224
3 4LEB THR THR THR THR THR THR THR 1.7094
4 3DSK T25 1.7094
5 3DOO SKM 1.80505
6 3COB ADP 1.9943
7 1YHM AHD 2.5641
8 5FPE 3TR 2.5641
9 1JT2 FER 2.61194
10 6BR8 PGV 2.77778
11 2X7I CIT 2.92208
12 3TK1 GDP 3.0303
13 2CJA ATP 3.1339
14 1ZCB GDP 3.1339
15 5M7S NHT 3.1339
16 5OE4 3UK 3.1339
17 1B0U ATP 3.43511
18 2HGS GSH 3.7037
19 5F90 GLA GAL BGC 5VQ 3.84615
20 2YLD CMO 3.93701
21 5ZYN SIN 3.9886
22 1JQN DCO 3.9886
23 4YJ1 ADP 3.9886
24 5H2U 1N1 4.11985
25 2VHJ ADP 4.22961
26 3GGF GVD 4.31894
27 5YLF BGC 4.49102
28 3ETH ATP 4.5584
29 1FQK GDP 4.7619
30 2PZE ATP 4.80349
31 5YRI GLC GLC 4.92958
32 1JJ7 ADP 5
33 3EJW PAV 5.07937
34 2F59 INI 5.09554
35 1XVB BBX 5.12821
36 5I3B HQE 5.22648
37 2D3S TNR 5.3719
38 2WPB ZZI 5.41311
39 2X1L MET 5.41311
40 2I4O ATP 5.41311
41 3OQJ 3CX 5.83658
42 5ZAI COA 6.17761
43 3GC8 B45 6.21622
44 1GSA ADP 6.32911
45 1ZDQ MSM 6.54762
46 5M36 9SZ 6.55022
47 4KVL PLM 6.55271
48 4CM9 YGL 6.59722
49 4BS0 6NT 6.60377
50 1VKJ A3P 6.66667
51 2NGR GDP 6.80628
52 1F20 NAP 6.83761
53 1S7N COA 6.83761
54 3MMH SME 7.18563
55 5AHW CMP 7.48299
56 5O3Q CMP 7.5
57 4IJ6 SEP 7.58294
58 6B5K TYD 8.10811
59 3K6V CIT 8.26211
60 2GNM MAN 8.33333
61 2GWH PCI 8.38926
62 4AG9 COA 8.48485
63 3F70 MLZ 8.54701
64 2ZPA ADP 8.83191
65 5HZ9 5M8 8.88889
66 2PRG BRL 9.09091
67 3ZW0 FUC 9.1954
68 1S16 ANP 9.68661
69 1PIG GLC GLC 10.5413
70 3K7S R52 10.6145
71 3JWH SAH 11.5207
72 1EJH M7G 12.1053
73 4QAR ADE 12.4378
74 3BFX A3P 15.2027
75 4XDA ADP 15.534
76 2V7Q ADP 18
Pocket No.: 8; Query (leader) PDB : 2C6Q; Ligand: IMP; Similar sites found with APoc: 14
This union binding pocket(no: 8) in the query (biounit: 2c6q.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 3RK0 AMP 2.1097
2 6BR8 PGV 2.77778
3 1NML CIT 3.06748
4 1P4V GLY 4.0678
5 4LPS GDP 4.13223
6 5IFS ADP 5.90717
7 2FWP ICR 6.01093
8 5CIC 51R 6.80272
9 2NGR GDP 6.80628
10 2CE7 ADP 8.54701
11 6CS9 PIO 9.7561
12 2D2F ADP 11.2
13 3BFX A3P 15.2027
14 3HCH RSM 23.2877
Pocket No.: 9; Query (leader) PDB : 2C6Q; Ligand: NDP; Similar sites found with APoc: 16
This union binding pocket(no: 9) in the query (biounit: 2c6q.bio2) has 43 residues
No: Leader PDB Ligand Sequence Similarity
1 3IHB GLU 1.9943
2 1Q19 SSC 2.5641
3 1T3D CYS 3.11419
4 1YRB GDP 4.58015
5 2B6N ALA PRO THR 5.39568
6 5HJQ I3P 5.41311
7 3PA8 621 6.29921
8 4QBK 3NZ 8.24742
9 3PQC GDP 9.23077
10 1KW6 BPY 9.58904
11 1M7G AV2 9.95261
12 3HF3 FMN 10.0287
13 6BR9 PGV 12.2507
14 5EHS 5OY 12.6866
15 5EHS 2JJ 12.6866
16 2W58 ADP 17.3267
Pocket No.: 10; Query (leader) PDB : 2C6Q; Ligand: IMP; Similar sites found with APoc: 23
This union binding pocket(no: 10) in the query (biounit: 2c6q.bio2) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 3B8I OXL 1.74216
2 5AOA PPI 1.9943
3 5AZC PGT 2
4 3FIU POP 2.00803
5 4JP3 CIT 2.09205
6 3L9W AMP 2.2792
7 1G6H ADP 2.33463
8 4WXJ GLU 2.60223
9 2V5K OXM 2.78746
10 3FPZ AHZ 3.37423
11 3HQP OXL 3.4188
12 1R6N 434 3.79147
13 4D79 ATP 4.71014
14 4P4M D3T 5.41311
15 1BZL FAD 5.69801
16 5F7J ADE 5.9375
17 4AF5 CIT 7.89474
18 1Q8P MAN MMA 8.33333
19 2F7A BEZ 8.62069
20 4R3U 5AD 9.68661
21 1M7G AV2 9.95261
22 3RHC GSH 11.5044
23 1P0Z FLC 15.2672
Pocket No.: 11; Query (leader) PDB : 2C6Q; Ligand: IMP; Similar sites found with APoc: 7
This union binding pocket(no: 11) in the query (biounit: 2c6q.bio2) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 1F76 ORO 2.97619
2 2XT3 ADP 4.65116
3 3BRE C2E 5.41311
4 4YMU ARG 7.5
5 5O74 GDP 8.62944
6 1BXG HCI 9.11681
7 6FXR UDP 13.9601
Pocket No.: 12; Query (leader) PDB : 2C6Q; Ligand: NDP; Similar sites found with APoc: 13
This union binding pocket(no: 12) in the query (biounit: 2c6q.bio2) has 44 residues
No: Leader PDB Ligand Sequence Similarity
1 1LOX RS7 2.849
2 5TWO 7MV 2.94118
3 2FGQ MLT 3.31325
4 3N29 GOL 3.4188
5 4PTN GXV 3.79009
6 1KUK PCA LYS TRP 4.92611
7 4Q9N 0WE 5.03356
8 1FWV SGA MAG FUC 5.22388
9 4QYS PLR 5.69801
10 5F7J ADE 5.9375
11 1OYB FMN 6.25
12 5URY PAM 6.84932
13 5T46 MGP 10.6061
Pocket No.: 13; Query (leader) PDB : 2C6Q; Ligand: IMP; Similar sites found with APoc: 15
This union binding pocket(no: 13) in the query (biounit: 2c6q.bio2) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 5LV1