Receptor
PDB id Resolution Class Description Source Keywords
2BZ1 1.54 Å EC: 3.5.4.25 CRYSTAL STRUCTURE OF APO E. COLI GTP CYCLOHYDROLASE II ESCHERICHIA COLI RIBOFLAVIN BIOSYNTHESIS GTP CYCLOHYDROLASE II CATALYTIC ZINC HYDROLASE MAGNESIUM
Ref.: GTP CYCLOHYDROLASE II STRUCTURE AND MECHANISM. J.BIOL.CHEM. V. 280 36912 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:1178;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
SO4 A:1175;
A:1176;
A:1177;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
TAU A:1179;
Valid;
none;
submit data
125.147 C2 H7 N O3 S C(CS(...
ZN A:1174;
Part of Protein;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2BZ1 1.54 Å EC: 3.5.4.25 CRYSTAL STRUCTURE OF APO E. COLI GTP CYCLOHYDROLASE II ESCHERICHIA COLI RIBOFLAVIN BIOSYNTHESIS GTP CYCLOHYDROLASE II CATALYTIC ZINC HYDROLASE MAGNESIUM
Ref.: GTP CYCLOHYDROLASE II STRUCTURE AND MECHANISM. J.BIOL.CHEM. V. 280 36912 2005
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2BZ1 - TAU C2 H7 N O3 S C(CS(=O)(=....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2BZ1 - TAU C2 H7 N O3 S C(CS(=O)(=....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4RL4 - PPV H4 O7 P2 OP(=O)(O)O....
2 2BZ1 - TAU C2 H7 N O3 S C(CS(=O)(=....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: TAU; Similar ligands found: 5
No: Ligand ECFP6 Tc MDL keys Tc
1 TAU 1 1
2 A20 0.631579 0.883721
3 9SB 0.473684 0.697674
4 COM 0.473684 0.804878
5 OCS 0.4 0.770833
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2BZ1; Ligand: TAU; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2bz1.bio1) has 7 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 2BZ1; Ligand: TAU; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2bz1.bio1) has 7 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback