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Receptor
PDB id Resolution Class Description Source Keywords
2BVN 2.3 Å EC: 3.6.1.48 E. COLI EF-TU:GDPNP IN COMPLEX WITH THE ANTIBIOTIC ENACYLOXI ESCHERICHIA COLI TRANSLATION ELONGATION FACTOR GTPASE ANTIBIOTIC GTP-BINDPHOSPHORYLATION
Ref.: ENACYLOXIN IIA PINPOINTS A BINDING POCKET OF ELONGA FACTOR TU FOR DEVELOPMENT OF NOVEL ANTIBIOTICS. J.BIOL.CHEM. V. 281 2893 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ENX A:1396;
B:1396;
Valid;
Valid;
none;
none;
submit data
702.616 C33 H45 Cl2 N O11 CC/C=...
GNP A:1394;
B:1394;
Valid;
Valid;
none;
none;
submit data
522.196 C10 H17 N6 O13 P3 c1nc2...
MG A:1395;
B:1395;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2BVN 2.3 Å EC: 3.6.1.48 E. COLI EF-TU:GDPNP IN COMPLEX WITH THE ANTIBIOTIC ENACYLOXI ESCHERICHIA COLI TRANSLATION ELONGATION FACTOR GTPASE ANTIBIOTIC GTP-BINDPHOSPHORYLATION
Ref.: ENACYLOXIN IIA PINPOINTS A BINDING POCKET OF ELONGA FACTOR TU FOR DEVELOPMENT OF NOVEL ANTIBIOTICS. J.BIOL.CHEM. V. 281 2893 2006
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1DG1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 2BVN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
3 1EFC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 6EZE - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
70% Homology Family (18)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1D2E Kd = 1 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 5W76 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 5W7Q - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 1DG1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 2BVN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
6 1EFC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 6EZE - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 4H9G - 14J C5 H3 Br O3 c1cc(oc1C(....
9 4LBZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
10 4LC0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
11 1EXM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
12 2C78 - PUL C47 H66 O13 C[C@@H]1[C....
13 1EFT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
14 4LBV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
15 4LBW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
16 1HA3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
17 4J0Q - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
18 5W75 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1D2E Kd = 1 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1DG1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 2BVN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 1EFC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 6EZE - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
6 4H9G - 14J C5 H3 Br O3 c1cc(oc1C(....
7 4LBZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 4J0Q - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
9 5W75 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ENX; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 ENX 1 1
Ligand no: 2; Ligand: GNP; Similar ligands found: 132
No: Ligand ECFP6 Tc MDL keys Tc
1 GNP 1 1
2 9GM 1 1
3 GDP 0.839506 0.973684
4 GP3 0.82716 0.948718
5 GTP 0.809524 0.973684
6 GNH 0.807229 0.986842
7 G1R 0.77907 0.961039
8 GCP 0.77907 0.948718
9 GSP 0.770115 0.925
10 5GP 0.756098 0.960526
11 G 0.756098 0.960526
12 G2R 0.747253 0.936709
13 GMV 0.747126 0.948718
14 GAV 0.714286 0.936709
15 GP2 0.712644 0.936709
16 G2P 0.711111 0.936709
17 Y9Z 0.708333 0.880952
18 GDC 0.690722 0.936709
19 GDD 0.690722 0.936709
20 GKE 0.690722 0.936709
21 G5P 0.686869 0.948718
22 GPG 0.684211 0.936709
23 GTG 0.683673 0.91358
24 GDR 0.683673 0.936709
25 GFB 0.683673 0.936709
26 JB2 0.68 0.936709
27 GKD 0.68 0.936709
28 6CK 0.676768 0.91358
29 G3A 0.676768 0.948718
30 GDX 0.673267 0.948718
31 ALF 5GP 0.67033 0.86747
32 YGP 0.663265 0.879518
33 GPD 0.656863 0.902439
34 ALF GDP 0.645833 0.86747
35 GDP AF3 0.645833 0.86747
36 GDP ALF 0.645833 0.86747
37 JB3 0.641509 0.925
38 DBG 0.640351 0.974359
39 G3D 0.638298 0.960526
40 G4P 0.625 0.960526
41 GMP 0.621951 0.857143
42 NGD 0.62037 0.936709
43 GGM 0.618182 0.925926
44 0O2 0.616162 0.960526
45 2MD 0.603604 0.870588
46 CAG 0.60177 0.904762
47 U2G 0.590909 0.91358
48 FEG 0.590909 0.858824
49 GDP 7MG 0.590476 0.888889
50 MGD 0.587719 0.870588
51 G G 0.586538 0.924051
52 ZGP 0.585586 0.848837
53 CG2 0.580357 0.91358
54 ANP 0.568421 0.922078
55 PGD 0.567797 0.902439
56 MD1 0.567797 0.870588
57 3GP 0.56044 0.922078
58 TPG 0.558333 0.822222
59 GH3 0.55 0.948052
60 FE9 0.546219 0.778947
61 GPX 0.539216 0.922078
62 G4M 0.539062 0.860465
63 DGI 0.536082 0.9
64 BGO 0.535088 0.901235
65 IDP 0.53125 0.947368
66 DGT 0.53 0.9
67 2GP 0.526882 0.935065
68 G1R G1R 0.520325 0.901235
69 GCP G 0.518868 0.897436
70 A G 0.516949 0.911392
71 U A G G 0.512605 0.911392
72 G A A A 0.504202 0.9
73 AGO 0.504202 0.91358
74 P2G 0.5 0.860759
75 G1G 0.5 0.902439
76 R7I 0.49505 0.922078
77 MGP 0.49505 0.936709
78 R5I 0.49505 0.922078
79 PGD O 0.492063 0.831461
80 6G0 0.490196 0.936709
81 P1G 0.489796 0.85
82 AKW 0.483051 0.869048
83 DG 0.474227 0.8875
84 DGP 0.474227 0.8875
85 G U 0.466667 0.878049
86 IMP 0.463918 0.934211
87 G2Q 0.462963 0.936709
88 GPC 0.459677 0.858824
89 G C 0.459016 0.878049
90 GTA 0.448276 0.91358
91 G7M 0.444444 0.924051
92 MAP 0.439252 0.898734
93 G G G RPC 0.435484 0.853659
94 B4P 0.434343 0.871795
95 AP5 0.434343 0.871795
96 ADP 0.434343 0.896104
97 A2D 0.43299 0.871795
98 AT4 0.43 0.8625
99 G G G C 0.426357 0.890244
100 AU1 0.425743 0.922078
101 SGP 0.425743 0.807229
102 BA3 0.424242 0.871795
103 A G C C 0.423077 0.888889
104 35G 0.423077 0.909091
105 PCG 0.423077 0.909091
106 C2E 0.423077 0.897436
107 APC G U 0.421875 0.864198
108 HEJ 0.421569 0.896104
109 ATP 0.421569 0.896104
110 ACQ 0.419048 0.873418
111 5GP 5GP 0.419048 0.860759
112 5FA 0.417476 0.896104
113 AQP 0.417476 0.896104
114 01G 0.417391 0.880952
115 AN2 0.415842 0.909091
116 UNP 0.415842 0.810127
117 6AD 0.415094 0.821429
118 M33 0.411765 0.860759
119 ITT 0.411765 0.846154
120 G C C C 0.410448 0.901235
121 HFD 0.409524 0.851852
122 G U34 0.408 0.86747
123 ACP 0.407767 0.873418
124 6YZ 0.407407 0.873418
125 AR6 0.403846 0.871795
126 APR 0.403846 0.871795
127 DG DG 0.403509 0.845238
128 A4P 0.403226 0.848837
129 UCG 0.402985 0.888889
130 SAP 0.4 0.851852
131 AGS 0.4 0.851852
132 AD9 0.4 0.873418
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2BVN; Ligand: ENX; Similar sites found with APoc: 52
This union binding pocket(no: 1) in the query (biounit: 2bvn.bio2) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 6BR9 PGV 1.39276
2 3S5W ONH 1.52672
3 2P41 G1G 1.63934
4 2GWH PCI 1.67785
5 4LIK CIT 1.78571
6 6BR8 PGV 1.98413
7 3ESS 18N 2.17391
8 1J78 OLA 2.29008
9 3A16 PXO 2.41287
10 3TDC 0EU 2.54453
11 6HL8 GUA 2.54958
12 4UCC ZKW 2.57511
13 6CB2 OLC 3.07167
14 5V3Y 5V8 3.14685
15 5LFV SIA GAL NAG 3.15457
16 4AP9 1PS 3.48259
17 5XJ7 87O 3.48259
18 2G30 ALA ALA PHE 3.48837
19 3WXL ADP 3.56234
20 6EK3 OUL 3.61991
21 1R6N 434 3.79147
22 2BCG GER 3.81679
23 4V3I ASP LEU THR ARG PRO 3.89105
24 4FK7 P34 3.93013
25 1UUY PPI 4.19162
26 5VKM GAL SIA 4.32099
27 3EVF GTA 4.33213
28 5LX9 OLB 4.58015
29 5IUY BOG 4.58015
30 2WOR 2AN 5
31 1OFL NGK GCD 5.08906
32 1USF NAP 5.61798
33 4FXQ G9L 5.85242
34 2V5E SCR 6.93069
35 2VDF OCT 7.11462
36 5YSI NCA 7.23684
37 5OCA 9QZ 8.29493
38 5LWY OLB 8.40336
39 6BJO DUY 8.8
40 3KO0 TFP 8.91089
41 4F4S EFO 10.5263
42 5W7B MYR 10.687
43 1XVB 3BR 11.1765
44 1VEM GLC GLC 12.9771
45 4OGQ 7PH 13.5135
46 4OGQ 1O2 13.5135
47 4RYV ZEA 18.7097
48 2Y69 CHD 22.5
49 5Z84 CHD 28.2609
50 5W97 CHD 28.2609
51 5ZCO CHD 28.2609
52 1M2Z BOG 28.5714
Pocket No.: 2; Query (leader) PDB : 2BVN; Ligand: GNP; Similar sites found with APoc: 672
This union binding pocket(no: 2) in the query (biounit: 2bvn.bio2) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 1EK0 GNP None
2 1D5C GDP 1.23457
3 1YTM ATP 1.27226
4 4Y4V DAL 1.47493
5 2WKQ GTP 1.50602
6 1V8K ANP 1.52672
7 5TSH ANP 1.52672
8 5TSH ADP 1.52672
9 5XDR ADP 1.52672
10 4FCW ADP 1.60772
11 1Z0F GDP 1.67598
12 2GWH A3P 1.67785
13 3ZS9 ADP ALF 1.69492
14 2WOJ ADP ALF 1.69492
15 3QVV A3P 1.69492
16 3QVV 3QV 1.69492
17 2G77 GDP 1.78117
18 5LB3 ADP 1.78117
19 5HR5 ADP 1.78117
20 2G77 AF3 1.78117
21 2XAU ADP 1.78117
22 1P9B GDP 1.80995
23 4ZNL BEF ADP 1.82482
24 1TAD ALF 1.85185
25 1TAD GDP 1.85185
26 1U0J ADP 1.87266
27 5L3W GDP 1.96078
28 2F9L GDP 2.01005
29 3IO3 ADP 2.01149
30 5KSZ GCP 2.03562
31 5IRN ADP 2.03562
32 5VGR GDP 2.03562
33 4YJ1 ADP 2.03562
34 1XKV ATP 2.03562
35 5XQL C2E 2.06186
36 1OIX GDP 2.09424
37 1OIV GDP 2.09424
38 1G6O ADP 2.12121
39 1MH1 GNP 2.15054
40 1G4U GDP 2.17391
41 1G4U AF3 2.17391
42 5MEX SZZ 2.17391
43 5MEX PAP 2.17391
44 2B8T THM 2.24215
45 4LX0 BEF GDP 2.25989
46 3DEF GDP 2.29008
47 2VVG ADP 2.29008
48 5AK0 8V1 2.29008
49 5ZXD ATP 2.29008
50 1K6M AGS 2.29008
51 1DNP MHF 2.29008
52 4A4Z ANP 2.29008
53 2DPY ADP 2.29008
54 1VHT BA3 2.29358
55 4LHW GNP 2.29885
56 5HCN GCP 2.29885
57 4R2I ANP 2.38095
58 2D7C GTP 2.39521
59 1E2K TMC 2.41692
60 3DZD ADP 2.44565
61 1R0X ATP 2.44755
62 2ZFI ADP 2.45902
63 3ZQ6 ADP ALF 2.46914
64 4LPS GDP 2.47934
65 4IXH IMP 2.49307
66 4P4T GDP 2.5
67 3FVQ ATP 2.50696
68 4KVA GTP 2.54453
69 1IHU ADP 2.54453
70 1IHU AF3 2.54453
71 2GKS ADP 2.54453
72 4IOK XPO 2.54453
73 4IOK ADP 2.54453
74 4HSE ADP 2.54453
75 5TIV A3P 2.54453
76 1OYY AGS 2.54453
77 5K5Z ANP 2.54777
78 1QXA GLY GLY GLY 2.55319
79 5KSP GDP 2.63158
80 3R7F CP 2.63158
81 5BQ5 ADP BEF 2.6455
82 5H68 AGS 2.64706
83 1CR1 TTP 2.7027
84 1F2U ATP 2.7027
85 3TMK T5A 2.77778
86 2Y8E GNP 2.7933
87 2QTV GNP 2.79898
88 1F5N GNP 2.79898
89 2C9O ADP 2.79898
90 1G41 ADP 2.79898
91 5AHM IMP 2.79898
92 5J1J ANP 2.80702
93 4TMK T5A 2.8169
94 4BQS K2Q 2.84091
95 4BQS ADP 2.84091
96 4PPF FLC 2.85714
97 2ZR9 DTP 2.86533
98 4WEI GLC GAL 2.88809
99 3QXC ATP 2.89256
100 1SVM ATP 2.91777
101 2FFQ GSP 2.92398
102 1YZQ GNP 2.94118
103 1R2Q GNP 2.94118
104 3QKT ANP 2.94985
105 3MJH GTP 2.97619
106 1ZUI SKM 2.97619
107 1RRC ADP 2.99003
108 3Q72 GNP 3.01205
109 5LLB 6YZ 3.04183
110 1OE0 TTP 3.04348
111 1GOT GDP 3.05344
112 5I0H ADP BEF 3.05344
113 3EZ2 ADP 3.05344
114 4IHQ ADP 3.05344
115 4YS0 ADP 3.05344
116 5MZN ADP 3.05344
117 1GOJ ADP 3.09859
118 2XTZ GSP 3.10734
119 3ZFD ANP 3.1339
120 3CPJ GDP 3.13901
121 3VX3 ADP 3.22581
122 4DKX GDP 3.24074
123 2FH5 GTP 3.24324
124 1P72 ADP 3.29341
125 4KFU ACP 3.30189
126 1QF5 RPL 3.30789
127 1QF5 GDP 3.30789
128 4XGU ADP 3.30789
129 4LYA ATP 3.30789
130 4PFO ADP 3.30789
131 4PJ3 ANP 3.30789
132 4O48 ASP 3.31325
133 2B8W ALF 5GP 3.35366
134 2OZE AGS 3.3557
135 2FNA ADP 3.36134
136 1JJV ATP 3.39806
137 5XC5 GTP 3.40909
138 3FYH ADP 3.41615
139 5X40 ACP 3.42466
140 4PX9 ADP 3.42466
141 1T5C ADP 3.4384
142 3B7G ANP 3.47826
143 3UIE ANP 3.5
144 4GOX A3P 3.51438
145 2ZE7 AMP 3.55731
146 2ZE7 DST 3.55731
147 1W0J ADP 3.56234
148 2CK3 ANP 3.56234
149 2CK3 ADP 3.56234
150 1W0J ADP BEF 3.56234
151 2ZPA ADP 3.56234
152 3TBK ANP 3.56234
153 5AHO TLA 3.57143
154 5G41 AP5 3.58744
155 1KAO GDP 3.59281
156 3H86 AP5 3.64583
157 3LRE ADP 3.66197
158 4XTR ATP 3.68664
159 4XVU ATP 3.68664
160 4XTR ADP 3.68664
161 1S3G AP5 3.68664
162 2Z5F A3P 3.69128
163 5UQW GDP 3.7037
164 4GBM A3P 3.71517
165 4JLV ADP 3.71747
166 2ZPT A3P 3.72881
167 2OBM ADP 3.7464
168 3WYF GTP 3.78151
169 4D0N GDP 3.78378
170 4WZ6 ATP 3.7931
171 1TU3 GNP 3.79747
172 1KMQ GNP 3.80435
173 4UXH T5A 3.80435
174 1Z06 GNP 3.81679
175 2BCG GDP 3.81679
176 3FKQ ATP 3.81679
177 3HU3 AGS 3.81679
178 2BIF ANP 3.81679
179 2BIF SIN 3.81679
180 5IFS ADP 3.81679
181 1R6B ADP 3.81679
182 3RC3 ANP 3.81679
183 1JJ7 ADP 3.84615
184 5GVR LMR 3.84615
185 1FNN ADP 3.85604
186 1VKJ A3P 3.85965
187 1MR3 G3D 3.8674
188 5M04 GDP 3.88889
189 4XOI GTP 3.88889
190 1G8S MET 3.91304
191 1I0B PEL 3.91566
192 1TX4 ALF GDP 3.9548
193 3ZIA ATP 3.95683
194 3ZIA ADP 3.95683
195 2EW1 GNP 3.9801
196 2ZTS ADP 3.98406
197 4D0G GTP 4
198 5ZBR ANP 4
199 2QG6 NMN 4.0201
200 6F5W KG1 4.06504
201 3SBD GNP 4.07125
202 2FAH GDP 4.07125
203 3DC4 ADP 4.07125
204 2AWN ADP 4.07125
205 5WRI A3P 4.07125
206 2FSH ANP 4.07125
207 4AG5 ADP 4.08163
208 2Q2Y ADP 4.08719
209 2Q2Y MKR 4.08719
210 3QF7 ANP 4.10959
211 1ION ADP 4.11523
212 3BOS CDP 4.13223
213 3Q85 GNP 4.14201
214 3TNF GNP 4.16667
215 5WC2 ADP 4.16667
216 2GDJ ANP 4.16667
217 5E5U MLI 4.16667
218 1L3I SAH 4.16667
219 5LEF GTP 4.18848
220 4HDO GNP 4.19162
221 3X1Z GNP 4.19162
222 4PVR ASP 4.19355
223 4YC7 GNP 4.19948
224 2J59 GTP 4.21687
225 1O3Y GTP 4.21687
226 1J2J GTP 4.21687
227 1G3Q ADP 4.21941
228 4GOJ GNP 4.2328
229 2X77 GDP 4.2328
230 2J0V GDP 4.24528
231 3QBT GNP 4.28571
232 5WRJ A3P 4.29043
233 5IRC GDP 4.30108
234 3RWO GDP 4.32432
235 4ZG4 VO4 ADP 4.3257
236 4X8O AP5 4.3257
237 3AQ4 GDP 4.34783
238 5L3V GDP 4.34783
239 5L3S GNP 4.36242
240 5L3S G 4.36242
241 2HF9 GSP 4.42478
242 2CHG ANP 4.42478
243 1RYH GNP 4.4335
244 1HE1 GDP 4.44444
245 1HE1 AF3 4.44444
246 2O66 FLC 4.44444
247 2GCO GNP 4.47761
248 2GCN GDP 4.47761
249 4U00 ADP 4.5082
250 3NHB ADP 4.57516
251 4ZI2 GNP 4.58015
252 1XMV ADP 4.58015
253 1OS1 PYR 4.58015
254 1OS1 ATP 4.58015
255 5G3Y ADP 4.58015
256 5LTJ ADP 4.58015
257 5LTJ BEF 4.58015
258 4NON GDP 4.61538
259 3Q9L ATP 4.61538
260 4KBF AMP 4.65753
261 4FRZ ADP 4.66321
262 4V03 ADP 4.66926
263 1Q20 PLO 4.68227
264 1Q20 A3P 4.68227
265 1Z08 GNP 4.70588
266 1J99 AND 4.77816
267 2PZE ATP 4.80349
268 1VG0 GDP 4.83092
269 1VG8 GNP 4.83092
270 3N5C GDP 4.83461
271 2A5F GTP 4.83461
272 1NY5 ADP 4.83461
273 4XFR CIT 4.83461
274 3COB ADP 4.87805
275 2JAQ DCP 4.87805
276 1DAK ADP 4.91071
277 1DAK DPU 4.91071
278 2IYL GDP 4.92958
279 1KY3 GDP 4.94506
280 2W58 ADP 4.9505
281 1RE0 GDP 4.97738
282 5XKT GNP 5
283 4Q1A UDP 5
284 4Q1A 2XZ 5
285 5H67 ATP 5
286 4LJ9 ACP 5.01475
287 2FJU GSP 5.05618
288 5OEC GDP 5.07614
289 4M9Q GNP 5.08906
290 2ZEJ GDP 5.08906
291 1LVK MNT BEF 5.08906
292 6A20 ADP 5.08906
293 1W5T ANP 5.08906
294 6H5E ANP 5.08906
295 1W5T ADP 5.08906
296 3FB4 AP5 5.09259
297 4TTQ ATP 5.11628
298 3KJI ADP 5.11811
299 1KO8 6PG 5.14286
300 1H65 GDP 5.18518
301 2O0J ADP 5.19481
302 2D2F ADP 5.2
303 2V5K OXM 5.22648
304 4YDS ATP 5.26316
305 5OCG GNP 5.29101
306 5KUT GDP 5.29101
307 5JCZ GDP 5.34351
308 4R43 GDP 5.34351
309 2NCD ADP 5.34351
310 5FHD ADP ALF 5.34351
311 5FTB ANP 5.34351
312 5BN3 ADP 5.34351
313 5VHC BEF ADP 5.34351
314 4D81 ADP 5.34351
315 4IDN GNP 5.34351
316 1IN4 ADP 5.38922
317 1VG1 GDP 5.40541
318 1VG9 GDP 5.40541
319 1UKZ ADP 5.41872
320 1XP8 AGS 5.46448
321 4XSH GSP 5.47945
322 2CBZ ATP 5.48523
323 5U32 GDP 5.50847
324 4MKG AP5 5.52995
325 1L2T ATP 5.53191
326 3T1O GDP 5.55556
327 5MVR ADP 5.55556
328 1UJ2 ADP 5.55556
329 1UJ2 C5P 5.55556
330 1WF3 GNP 5.59796
331 6CRK GDP 5.59796
332 1GP2 GDP 5.59796
333 5KDO GDP 5.59796
334 1SVK ALF GDP 5.59796
335 3BFX A3P 5.59796
336 3PCR GTP 5.60224
337 3E5H GNP 5.61798
338 6BSX GDP 5.61798
339 6BSX E7S 5.61798
340 3REF GDP 5.6701
341 5Z2M GTP 5.68182
342 1YRB GDP 5.72519
343 3LXR GDP 5.72917
344 1P4V GLY 5.76271
345 6FA4 GNP 5.78035
346 2RGX AP5 5.82524
347 2BEK ATP 5.83658
348 5IRR GSP 5.84416
349 5M7P ADP 5.85242
350 2IXE ATP 5.85242
351 1G3M A3P 5.85242
352 1G3M PCQ 5.85242
353 1IWE IMP 5.9081
354 2BME GNP 5.91398
355 1YZN GNP 5.94595
356 1BO4 COA 5.95238
357 2CDN ADP 5.97015
358 1Y63 ADP 5.97826
359 2QQ0 THM 5.97826
360 2QQ0 ANP 5.97826
361 2QQ0 TMP 5.97826
362 2QQ0 ADP 5.97826
363 4MKF AP5 5.99078
364 6BC0 GSP 6
365 1BH2 GSP 6.03175
366 3FWY ADP 6.05096
367 1TQ4 GDP 6.05327
368 2C5A NAD 6.0686
369 2C5A GDC 6.0686
370 5GOE GDP 6.10687
371 4WZA ACP 6.10687
372 4WZA ADP 6.10687
373 3T34 GDP 6.10687
374 5I34 GDP 6.10687
375 3DKP ADP 6.12245
376 4U5X GNP 6.17978
377 1M2O GNP 6.31579
378 2PL3 ADP 6.35593
379 4YLG GDP 6.35838
380 1FP6 ADP 6.36132
381 1X6V ADP 6.36132
382 1Z6T ADP 6.36132
383 4IEE AGS 6.36132
384 4K81 GTP 6.43275
385 4QM7 GTP 6.43275
386 4NU0 AP5 6.45161
387 4V0K GDP 6.50888
388 5E95 GDP 6.54762
389 6D5G GNP 6.58683
390 6D5E GNP 6.58683
391 6D5J GNP 6.58683
392 6BVL GNP 6.58683
393 6BVJ GNP 6.58683
394 6D59 GNP 6.58683
395 6D5V GNP 6.58683
396 6BVI GNP 6.58683
397 6D56 GNP 6.58683
398 6D5H GNP 6.58683
399 6BVK GNP 6.58683
400 6D5L GNP 6.58683
401 6BVM GNP 6.58683
402 6D55 GNP 6.58683
403 6D5M GNP 6.58683
404 1GXU 2HP 6.59341
405 1CLU DBG 6.62651
406 3DDC GNP 6.62651
407 3KUD GDP 6.62651
408 1WQ1 GDP 6.62651
409 1NVV GNP 6.62651
410 1WQ1 AF3 6.62651
411 4WOP CTP 6.66667
412 3H4S ADP 6.66667
413 1JI0 ATP 6.66667
414 2OG2 MLI 6.68524
415 2VB6 ADP BEF 6.71141
416 2C5L GTP 6.83761
417 2Y65 ADP 6.84932
418 3CX8 GSP 6.87023
419 3AB3 GDP 6.87023
420 1ZCB GDP 6.87023
421 1RJ9 GCP 6.87023
422 1F9V ADP 6.87023
423 1S9D GDP 6.89655
424 5O2T GSP 6.95187
425 4OI4 ATP 6.95652
426 2GJ8 ALF GDP 6.97674
427 2XT3 ADP 6.97674
428 3MD0 GDP 7.04225
429 5UIV ADP 7.04846
430 5ZB0 TYD 7.07071
431 5ZB0 ADP 7.07071
432 1OXV ANP 7.08215
433 2RCN GDP 7.12468
434 3P4X ADP 7.12468
435 4QOS ADP 7.12468
436 5BYK A3P 7.12468
437 5BYK OAQ 7.12468
438 1FZQ GDP 7.18232
439 2EFE GNH 7.18232
440 4OHY ANP 7.37913
441 5SZH GNP 7.38916
442 4LC1 GDP 7.4184
443 3RLF ANP 7.43243
444 1ZJ6 G3D 7.48663
445 2D7D ADP 7.5
446 2W2X GSP 7.56757
447 2V7Q ATP 7.57576
448 2V7Q ADP 7.57576
449 1HTW ADP 7.59494
450 3E70 GDP 7.62195
451 1Z83 AP5 7.65306
452 1YVD GNP 7.69231
453 1OW3 GDP 7.77202
454 2HV8 GTP 7.8125
455 3TK1 GDP 7.87879
456 2IS6 ADP 7.88804
457 3B9Q MLI 7.94702
458 1BG2 ADP 8
459 1B0U ATP 8.01527
460 1AQU A3P 8.08081
461 1YQT ADP 8.14249
462 5YV5 ADP 8.14249
463 3TKL GTP 8.16327
464 1FQK GDP 8.16327
465 1FQK ALF 8.16327
466 5L3R GCP 8.19113
467 6CS8 F9Y 8.25082
468 1GWN GTP 8.29268
469 5O74 GDP 8.33333
470 1DS6 GDP 8.33333
471 1I4D GDP 8.33333
472 1E96 GTP 8.37438
473 3M1I GTP 8.37696
474 2KIN ADP 8.40336
475 4C4P GNP 8.41121
476 1PUJ GNP 8.51064
477 4HI0 GDP 8.54271
478 3NKV GNP 8.57143
479 6BCA GSP 8.60927
480 2OFW ADX 8.65385
481 1Z0K GTP 8.72093
482 1T8U UAP SGN IDS SGN 8.82353
483 1T8U A3P 8.82353
484 3SFV GDP 8.83978
485 3A4M ADP 8.84615
486 4DCT GDP 8.90585
487 1S8F GDP 8.90585
488 1NHX FTB 8.90585
489 1NHX PEP 8.90585
490 2GMV UN8 8.90585
491 2GMV PEP 8.90585
492 1YZG GDP 8.93855
493 3NC9 TR3 8.94569
494 2XTN GTP 8.97436
495 5NM7 GLY 9.02256
496 3B5J 12D 9.0535
497 1R4A GNP 9.09091
498 1LVG ADP 9.09091
499 4GDX GLU 9.23077
500 6B8B ADP 9.23695
501 1M7B GTP 9.23913
502 4NE2 SH2 9.28144
503 4NE2 ADP 9.28144
504 2GK6 ADP 9.41476
505 2QEN ADP 9.42857
506 3IIJ ADP 9.44444
507 2PEZ GGZ 9.49721
508 2PEZ DAT 9.49721
509 6BCB GSP 9.58904
510 3BFV ADP 9.5941
511 1B7T ADP 9.61539
512 1KK8 BEF ADP 9.74026
513 4BFW ZVW 9.74843
514 1OFH ADP 9.77011
515 5JCP GDP ALF 9.7852
516 4DID GDP 9.84456
517 5EE5 GTP 9.85915
518 3KTA AP5 9.89011
519 4ZDJ UTP 9.92366
520 2WMO GTP 10
521 1NJF AGS 10
522 1NJF ADP 10
523 4BAS GNP 10.0503
524 1SQ5 ADP 10.0649
525 5CK5 GDP 10.1266
526 4E03 ADP 10.1942
527 1NF3 GNP 10.2564
528 5UPK GNP 10.2703
529 4TL6 ANP 10.2767
530 1D2N ANP 10.2941
531 1QF9 C5P 10.3093
532 1QF9 ADP 10.3093
533 1QF9 ALF 10.3093
534 5HPY GDP 10.3448
535 3GJ4 GDP 10.4072
536 3GJ5 GDP 10.4072
537 3GJ8 GDP 10.4072
538 3GJ3 GDP 10.4072
539 3GJ0 GDP 10.4072
540 2CJW GDP 10.4167
541 1ZIN AP5 10.4326
542 2ZJ5 ADP 10.4326
543 1XEX ATP 10.4396
544 1A4R GDP 10.4712
545 1A4R GNH 10.4712
546 2NGR GDP 10.4712
547 1GRN GDP 10.4712
548 4ITR GDP 10.4712
549 1GRN AF3 10.4712
550 2NGR AF3 10.4712
551 2UZI GTP 10.5769
552 5BXQ GDP 10.6481
553 1IBR GNP 10.6481
554 2A9K GDP 10.6952
555 5N69 ADP 11.0553
556 4H1V GNP 11.1111
557 4RZ3 ADP 11.1864
558 6AU6 GDP 11.1959
559 5Y6N ADP 11.1959
560 6B4K ANP 11.1959
561 3GJ7 GDP 11.2245
562 6ACS CIT 11.2403
563 5DI3 GNP 11.3514
564 5J1S ATP 11.3821
565 1UAD GNP 11.4286
566 1ZC3 GNP 11.4286
567 2QZ4 ADP 11.4504
568 5EXT ADP 11.5385
569 5WLB GNP 11.7647
570 3T12 GDP ALF 11.7647
571 4DDY DN6 11.7871
572 1M7G ADX 11.8483
573 1M7G AV2 11.8483
574 1M7G ADP 11.8483
575 1U8Z GDP 11.9048
576 2YOH WMJ 11.9048
577 3GJX GTP 12.037
578 2A5J GDP 12.0419
579 5Z69 AGS 12.0968
580 3CNL GNP 12.2137
581 2CE7 ADP 12.2137
582 2WIC GNP 12.3596
583 1CS4 GSP 12.7226
584 1G6H ADP 12.8405
585 4HAT GNP 12.8571
586 1WA5 GTP 13.0682
587 1Z2A GDP 13.0952
588 1Z0A GDP 13.2184
589 1W7J ADP BEF 13.245
590 2ORV 4TA 13.2479
591 6DEF GCP 13.2992
592 1SVI GDP 13.3333
593 4QRH 0O2 13.3333
594 6C90 ADP 13.4615
595 2HT6 GDP 13.486
596 4NCN GTP 13.486
597 1WDT GTP 13.486
598 1AKY AP5 13.6364
599 3T5G GDP 13.8158
600 5TB5 GDP 14
601 5TAR GDP 14.1892
602 1XX6 ADP 14.6597
603 3RAB GNP 14.7929
604 1G16 GDP 15.2941
605 4TMZ GSP 15.3623
606 5UWP GNP 15.3846
607 6CIT GNP 15.3846
608 5UWQ GNP 15.3846
609 5UWR GNP 15.3846
610 5UWJ GNP 15.3846
611 5UWI GNP 15.3846
612 5UWH GNP 15.3846
613 5UWT GNP 15.3846
614 5UWO GNP 15.3846
615 5UWW GNP 15.3846
616 5UWU GNP 15.3846
617 5UWS GNP 15.3846
618 5DI9 GNP 15.3846
619 4ZKD GDP 15.5216
620 1G7S GDP 15.5216
621 1DAR GDP 15.5216
622 3EC1 GDP 15.5216
623 2ODE ALF GDP 15.6028
624 4YMU ATP 15.8333
625 1W4R TTP 15.8974
626 4B47 GDP 15.978
627 1F6B GDP 16.1616
628 2WHX ADP 16.285
629 2JLR ANP 16.285
630 1UPT GTP 16.6667
631 2OM2 GDP 16.6667
632 3A1S GDP 17.0543
633 3EWA ANP 17.3913
634 1CXZ GSP 17.4419
635 3W5J GDP 17.5573
636 1KSH GDP 18.2796
637 1NRJ GTP 18.3486
638 3WYG GTP 18.4211
639 3BC1 GNP 18.4615
640 1NN5 ANP 18.6047
641 1NN5 2DT 18.6047
642 5WDR GNP 18.7134
643 4CVN ADP 18.8482
644 4KVG GTP 19.0476
645 1MKY GDP 19.5929
646 1ZD9 GDP 19.6809
647 4R98 GNH 19.9262
648 5H7K GDP 20.8651
649 5H7J GCP 20.8651
650 1GUA GNP 21.5569
651 1LFD GNP 21.8391
652 1Z0J GTP 22.0339
653 2W83 GTP 22.0779
654 3DOE GTP 23.4375
655 1X1R GDP 23.5955
656 6G14 G4P 24.4275
657 4KAX GTP 25.4658
658 2WJG GDP 26.0638
659 3PQC GDP 26.1538
660 3CH5 GDP 28.8462
661 2WJH GDP 29.5181
662 2WJH FLC 29.5181
663 5FG3 GDP 29.771
664 4HDQ GNP 30.7692
665 1FQJ GDP 30.9524
666 1FQJ ALF 30.9524
667 5DIF GNP 31.5789
668 5YT0 GDP 31.5934
669 4RD0 GDP 35.8779
670 2QN6 GDP 36.1323
671 2VOH CIT 42.3077
672 1KK1 GNP 42.4936
673 1Y3A GDP 50
Pocket No.: 3; Query (leader) PDB : 2BVN; Ligand: GNP; Similar sites found with APoc: 8
This union binding pocket(no: 3) in the query (biounit: 2bvn.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 4B9E FAH 1.3289
2 4M7V RAR 1.71429
3 6FAA ADP 1.78117
4 6C0B MLI 3.20513
5 3CV2 OXL 3.56234
6 3GDN MXN 3.81679
7 1PVN MZP 7.71277
8 1APZ ASP 9.21986
Pocket No.: 4; Query (leader) PDB : 2BVN; Ligand: ENX; Similar sites found with APoc: 7
This union binding pocket(no: 4) in the query (biounit: 2bvn.bio1) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 1SJD NPG 2.98913
2 5LX6 78P 3.14136
3 1XQP 8HG 3.90625
4 5N26 73M 4.3956
5 1DTL BEP 4.96894
6 2ET1 GLV 6.46766
7 2WH8 II2 6.87023
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