Receptor
PDB id Resolution Class Description Source Keywords
2BDG 1.95 Å EC: 3.4.21.- HUMAN KALLIKREIN 4 COMPLEX WITH NICKEL AND P-AMINOBENZAMIDIN HOMO SAPIENS SERINE PROTEINASE S1 SUBSITE 70-80 LOOP STRUCTURAL PROTEOEUROPE SPINE STRUCTURAL GENOMICS HYDROLASE
Ref.: CRYSTAL STRUCTURES OF HUMAN TISSUE KALLIKREIN 4: AC MODULATION BY A SPECIFIC ZINC BINDING SITE. J.MOL.BIOL. V. 362 1094 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CL A:404;
B:403;
 Invalid;
Invalid;
 none;
none;
 submit data
35.453 Cl [Cl-]
NA A:401;
A:402;
 Part of Protein;
Part of Protein;
 none;
none;
 submit data
22.99 Na [Na+]
NI A:405;
A:408;
B:406;
B:407;
 Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
 none;
none;
none;
none;
 submit data
58.693 Ni [Ni+2...
PBZ A:301;
B:302;
 Valid;
Valid;
 none;
none;
 submit data
136.174 C7 H10 N3 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2BDG 1.95 Å EC: 3.4.21.- HUMAN KALLIKREIN 4 COMPLEX WITH NICKEL AND P-AMINOBENZAMIDIN HOMO SAPIENS SERINE PROTEINASE S1 SUBSITE 70-80 LOOP STRUCTURAL PROTEOEUROPE SPINE STRUCTURAL GENOMICS HYDROLASE
Ref.: CRYSTAL STRUCTURES OF HUMAN TISSUE KALLIKREIN 4: AC MODULATION BY A SPECIFIC ZINC BINDING SITE. J.MOL.BIOL. V. 362 1094 2006
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 15 families.
1 2BDG - PBZ C7 H10 N3 c1cc(ccc1C....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 13 families.
1 6QFE ic50 = 0.08 uM J08 C23 H22 N6 O [H]/N=C(/c....
2 2BDG - PBZ C7 H10 N3 c1cc(ccc1C....
50% Homology Family (468)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1V2V Ki = 427 uM BEN C7 H8 N2 [H]/N=C(c1....
2 2ZDN - 49U C21 H30 N4 O2 [H]/N=C(c1....
3 2ZQ1 - 11U C21 H31 N5 O2 [H]/N=C(/c....
4 1TNH Ki = 0.43 mM FBA C7 H9 F N c1cc(ccc1C....
5 2BYA - BAM C7 H9 N2 c1ccc(cc1)....
6 6SV0 - BEN C7 H8 N2 [H]/N=C(c1....
7 1Y5A Ki = 1.33 uM TL2 C20 H22 N4 O4 [H]/N=C(c1....
8 5MNG - BAM C7 H9 N2 c1ccc(cc1)....
9 6SW0 - BEN C7 H8 N2 [H]/N=C(c1....
10 2AYW - ONO C28 H31 N5 O6 CC(C)(C)[C....
11 6SV9 - BEN C7 H8 N2 [H]/N=C(c1....
12 6SVR - BEN C7 H8 N2 [H]/N=C(c1....
13 1Y3Y Ki = 2300 nM UIR C27 H30 N4 O3 c1cc(ccc1[....
14 3PTB - BEN C7 H8 N2 [H]/N=C(c1....
15 5FXL - BEN C7 H8 N2 [H]/N=C(c1....
16 1O2I Ki = 0.052 uM 655 C19 H20 N4 O2 c1cc(c(c(c....
17 1GI6 Ki = 1.7 uM 124 C15 H14 N3 O c1ccc(c(c1....
18 5MON Kd = 3.3 mM 2AP C5 H7 N2 c1cc[nH+]c....
19 1O3D Ki = 0.074 uM 780 C20 H16 N4 O c1ccc(cc1)....
20 5F6M - BEN C7 H8 N2 [H]/N=C(c1....
21 1Y59 Ki = 1.19 uM TL1 C20 H22 N4 O4 c1cc(cc(c1....
22 1O39 Ki = 0.074 uM 780 C20 H16 N4 O c1ccc(cc1)....
23 1QL7 Kd = 15 uM ZEN C25 H27 Cl N4 O3 S c1cc(cc2c1....
24 2ZDM - 46U C21 H30 N4 O3 [H]/N=C(/c....
25 3NK8 - JKZ C9 H8 F3 N O C1CC2=C(C1....
26 1C2I - BAK C17 H16 N8 O c1cc2c(cc1....
27 1C2E - BAK C17 H16 N8 O c1cc2c(cc1....
28 1G3C Ki = 1.6 uM 109 FE 109 n/a n/a
29 1YP9 Ki = 7700 nM UIZ C31 H32 N4 O3 [H]/N=C(/c....
30 6B6T - BEN C7 H8 N2 [H]/N=C(c1....
31 1V2L Ki = 51 uM BEN C7 H8 N2 [H]/N=C(c1....
32 1Y3X Ki = 7315 nM UIB C26 H32 N4 O3 CC[C@@H]1[....
33 1OYQ Ki = 110 nM T87 C29 H31 N7 O3 [H]/N=C(/c....
34 6SY3 Ki = 497 uM LXW C26 H28 N4 O2 c1ccc(cc1)....
35 1XUG Ki = 0.09 uM BAB C17 H19 N8 c1cc2c(cc1....
36 3AAU Ki = 9 uM GZC CU n/a n/a
37 1C5S Ki = 1 uM ESX C9 H9 N2 S c1ccc2c(c1....
38 1V2N Ki = 1.25 uM BBA C23 H28 N4 O c1cc(ccc1C....
39 1XUH - BAO C17 H14 N8 O c1cc2c(cc1....
40 2G8T - MI2 C16 H15 N3 [H]/N=C(c1....
41 2BY8 - BAM C7 H9 N2 c1ccc(cc1)....
42 5MN1 Kd = 3.3 mM 2AP C5 H7 N2 c1cc[nH+]c....
43 1XUK Ki = 19 uM BAB C17 H19 N8 c1cc2c(cc1....
44 1V2J Ki = 566 uM BEN C7 H8 N2 [H]/N=C(c1....
45 5EG4 Ki = 21 nM 5N7 C42 H56 N10 O6 S [H]/N=C(c1....
46 6SVJ - BEN C7 H8 N2 [H]/N=C(c1....
47 1K1N Kd = 153 nM CCR C29 H39 N5 O7 S Cc1cc(c(c(....
48 1V2M Ki = 51 uM BEN C7 H8 N2 [H]/N=C(c1....
49 1C1T - BAB C17 H19 N8 c1cc2c(cc1....
50 1G3E Ki = 4.2 uM 109 C11 H15 N3 O3 C[C@@H](C(....
51 2FX6 Ki = 200 uM 270 C7 H7 N3 C1=CC2=NC(....
52 2ZQ2 Kd = 276 nM 13U C23 H35 N5 O2 [H]/N=C(/c....
53 1MTW - DX9 C26 H28 N4 O3 [H]/N=C(C)....
54 1QA0 - 270 C7 H7 N3 C1=CC2=NC(....
55 1F0T Ki = 1000 nM PR1 C19 H19 N5 O4 S2 c1cc2c(cc(....
56 1O3E Ki = 0.011 uM 696 C21 H17 N3 O c1ccc(cc1)....
57 1AZ8 - IN4 C20 H24 N4 O2 [H]/N=C(c1....
58 1Y3W Ki = 1680 nM UIP C26 H30 N4 O3 CC[C@@H]1[....
59 2BY9 - BAM C7 H9 N2 c1ccc(cc1)....
60 1QB6 Ki = 870 nM 623 C20 H18 F2 N5 O2 [H]/N=C(/c....
61 1O3N - 785 C15 H11 F3 N4 O2 c1cc2c(cc1....
62 3GY3 Kd = 2.36 uM PNT C19 H24 N4 O2 c1cc(ccc1C....
63 3NKK Kd = 20 uM JLZ C8 H9 F N2 [H]/N=C(/c....
64 3GY4 Kd = 8 uM PBZ C7 H10 N3 c1cc(ccc1C....
65 1TNL Ki = 13.3 mM TPA C9 H12 N c1ccc(cc1)....
66 1C2K - ABI C8 H9 N4 c1cc2c(cc1....
67 1V2K Ki = 0.65 uM ZEN C25 H27 Cl N4 O3 S c1cc(cc2c1....
68 1O3J Ki = 0.17 uM 334 C15 H13 Br N4 O Cc1cc(c(c(....
69 2BZA Ki = 1.58 mM ABN C7 H9 N c1ccc(cc1)....
70 2ZDK - 50U C22 H32 N4 O2 [H]/N=C(/c....
71 5MNQ Kd = 3.6 uM J3I C21 H32 N6 O2 [H]/N=C(N)....
72 1C5P Ki = 21 uM BAM C7 H9 N2 c1ccc(cc1)....
73 1K1M Kd = 40 nM FD4 C26 H29 N5 O4 S CC(=O)N1CC....
74 6B6R - BEN C7 H8 N2 [H]/N=C(c1....
75 1MTS - BX3 C27 H30 N4 O3 CC(=N)N1CC....
76 1UTO Kd = 5.32 mM PEA C8 H12 N c1ccc(cc1)....
77 3AAS Ki = 31 uM GUS C11 H14 N4 O3 [H]/N=C(N)....
78 1TNK Ki = 32.5 mM PRA C9 H13 N c1ccc(cc1)....
79 3GY7 Kd = 30 uM BEN C7 H8 N2 [H]/N=C(c1....
80 1O30 Ki = 0.17 uM 693 C24 H17 F N4 O5 c1ccc(c(c1....
81 2BY6 - BAM C7 H9 N2 c1ccc(cc1)....
82 2AGG - SIN ALA ALA PRO LYS n/a n/a
83 6T5W Ki = 47 uM J5K C20 H25 N5 O2 c1ccc(cc1)....
84 3GY5 Kd = 1.8 uM BRN C14 H15 N7 c1cc(ccc1C....
85 1S0R - BEN C7 H8 N2 [H]/N=C(c1....
86 6B6N - BEN C7 H8 N2 [H]/N=C(c1....
87 1C5Q Ki = 0.44 uM ESI C9 H8 I N2 S c1cc2c(cc(....
88 3T25 - BEN C7 H8 N2 [H]/N=C(c1....
89 1GHZ Ki = 16 uM 120 C13 H12 N5 O c1cc2c(cc1....
90 1C5U - ESP C8 H8 N3 S c1cc2cc(sc....
91 1N6X - ABN C7 H9 N c1ccc(cc1)....
92 1O2V Ki = 1.4 uM 847 C18 H13 Br N4 O5 c1cc2c(cc1....
93 1V2Q Ki = 73.62 uM ANH C20 H24 N4 O5 S Cc1ccc(cc1....
94 6SV8 - BEN C7 H8 N2 [H]/N=C(c1....
95 1TNG Ki = 1.17 mM AMC C7 H16 N C1CCC(CC1)....
96 3T26 - BEN C7 H8 N2 [H]/N=C(c1....
97 6FID - BEN C7 H8 N2 [H]/N=C(c1....
98 5MNO Kd = 143 uM MRZ C6 H13 N3 [H]/N=C(N)....
99 4YTA - BEN C7 H8 N2 [H]/N=C(c1....
100 1GI4 Ki = 0.065 uM 122 C14 H13 N4 O c1ccc(c(c1....
101 1BTY - BEN C7 H8 N2 [H]/N=C(c1....
102 1K1P - MEL C22 H31 N5 O4 c1cc(ccc1C....
103 1V2T Ki = 19.56 uM ANH C20 H24 N4 O5 S Cc1ccc(cc1....
104 1O3G Ki = 0.011 uM 696 C21 H17 N3 O c1ccc(cc1)....
105 2TIO - BEN C7 H8 N2 [H]/N=C(c1....
106 1C2D Ki = 0.0052 uM BAK C17 H16 N8 O c1cc2c(cc1....
107 1C1R Ki = 0.0235 uM BAI C16 H14 N6 c1ccc2c(c1....
108 1C2H - BAK C17 H16 N8 O c1cc2c(cc1....
109 1O36 Ki = 1.1 uM 607 C24 H19 N5 O5 c1ccc(c(c1....
110 2BY7 - BAM C7 H9 N2 c1ccc(cc1)....
111 3GY8 Kd = 1.8 uM BRN C14 H15 N7 c1cc(ccc1C....
112 5T3H - BEN C7 H8 N2 [H]/N=C(c1....
113 3ITI ic50 = 0.27 uM BRV C8 H4 Br3 N O4 c1(c(c(c(c....
114 2ZFS - 12U C22 H33 N5 O2 [H]/N=C(/c....
115 3GY6 Kd = 1.8 uM BRN C14 H15 N7 c1cc(ccc1C....
116 1O3L - 678 C17 H13 Br N3 O3 c1cc2c(cc1....
117 1BJU Ki = 6.2 uM GP6 C14 H13 Cl N4 O [H]/N=C(c1....
118 1XUJ Ki < 1 nM BOZ C17 H18 N8 O Zn c1cc2c(cc1....
119 1TX7 Ki = 25 uM 4CM C8 H11 N2 O2 P C[P@](=O)(....
120 6B6O - BEN C7 H8 N2 [H]/N=C(c1....
121 3M35 - M35 C25 H20 F4 N4 O3 S CS(=O)(=O)....
122 1MTU - BX3 C27 H30 N4 O3 CC(=N)N1CC....
123 1O32 Ki = 1.8 uM 801 C13 H11 N5 O c1cc(c(nc1....
124 3T27 - BEN C7 H8 N2 [H]/N=C(c1....
125 5LH4 - 6W4 C32 H34 N6 O2 c1ccc(cc1)....
126 1O2Q Ki = 0.021 uM 991 C20 H20 Cl N3 O2 c1cc(c(c(c....
127 1K1J Kd = 28 nM FD2 C27 H30 N4 O5 S [H]/N=C(/c....
128 5MNN - MRZ C6 H13 N3 [H]/N=C(N)....
129 1C1S - BAB C17 H19 N8 c1cc2c(cc1....
130 1QBO Ki = 18 nM 711 C27 H31 N6 O Cc1[nH]c2c....
131 1V2R Ki = 278.96 uM ANH C20 H24 N4 O5 S Cc1ccc(cc1....
132 1C5R - ESI C9 H8 I N2 S c1cc2c(cc(....
133 6SVV - BEN C7 H8 N2 [H]/N=C(c1....
134 1K1O - IGN C21 H38 N6 O4 C1CCC(CC1)....
135 2ZFT - 10U C20 H29 N5 O2 c1cc(ccc1C....
136 1TIO - BAM C7 H9 N2 c1ccc(cc1)....
137 1V2U Ki = 427 uM BEN C7 H8 N2 [H]/N=C(c1....
138 1MTV - BX3 C27 H30 N4 O3 CC(=N)N1CC....
139 1Y5B Kd = 1.26 uM TL3 C20 H22 N4 O4 c1cc(ccc1C....
140 1G36 Ki = 67 nM R11 C25 H25 N7 [H]/N=C(/c....
141 6SVZ - BEN C7 H8 N2 [H]/N=C(c1....
142 1O2L - 762 C20 H15 Cl N4 O c1ccc(cc1)....
143 1TX8 Ki = 1800 uM AM4 C8 H10 N2 O2 S CS(=O)(=O)....
144 1GI1 Ki = 3.6 uM BMZ C14 H13 N4 O c1ccc(c(c1....
145 1V2W Ki = 97.79 uM ANH C20 H24 N4 O5 S Cc1ccc(cc1....
146 6SV6 - BEN C7 H8 N2 [H]/N=C(c1....
147 1O3H Ki = 0.05 uM 907 C16 H14 Br N3 O Cc1cc(c(c(....
148 4NCY - BEN C7 H8 N2 [H]/N=C(c1....
149 1O35 - 802 C14 H11 F N4 O c1cc2c(cc1....
150 1PPC Ki = 0.69 uM MID C27 H31 N5 O4 S [H]/N=C(/c....
151 1TNI Ki = 0.1 mM PBN C10 H15 N c1ccc(cc1)....
152 6SVU - BEN C7 H8 N2 [H]/N=C(c1....
153 1V2S Ki = 68 uM BEN C7 H8 N2 [H]/N=C(c1....
154 1LQE Ki = 1507 nM IMA C34 H36 N5 O2 C[N+](C)(C....
155 1O2S Ki = 3.4 uM CR4 C14 H12 N4 O c1ccc(c(c1....
156 1O3M - 785 C15 H11 F3 N4 O2 c1cc2c(cc1....
157 6E5M - CYS THR LYS SER ILE PRO PRO GLN CYS n/a n/a
158 1O2X Ki = 1.4 uM 847 C18 H13 Br N4 O5 c1cc2c(cc1....
159 1O38 Ki = 0.15 uM 653 C22 H22 N5 O c1ccc(cc1)....
160 1G3B Ki = 1.8 uM 108 C11 H15 N3 O3 C[C@@H](C(....
161 1BJV Ki = 13 uM GP8 C20 H18 N4 O2 c1ccc(cc1)....
162 1C1P - BAI C16 H14 N6 c1ccc2c(c1....
163 1C2J - BAK C17 H16 N8 O c1cc2c(cc1....
164 1C2F - BAH C17 H18 N8 O2 c1cc2c(cc1....
165 3LJJ Kd = 300 nM 10U C20 H29 N5 O2 c1cc(ccc1C....
166 1O3I Ki = 0.05 uM 907 C16 H14 Br N3 O Cc1cc(c(c(....
167 1Y3V Ki = 2300 nM UIR C27 H30 N4 O3 c1cc(ccc1[....
168 1UTP Kd = 36 mM PBN C10 H15 N c1ccc(cc1)....
169 2BLV - BEN C7 H8 N2 [H]/N=C(c1....
170 6SVG - BEN C7 H8 N2 [H]/N=C(c1....
171 1TNJ Ki = 11 mM PEA C8 H12 N c1ccc(cc1)....
172 3GY2 Kd = 1.8 uM BRN C14 H15 N7 c1cc(ccc1C....
173 6T0M Ki = 39 uM GOZ C20 H26 N6 O2 c1ccc(cc1)....
174 6B6S - BEN C7 H8 N2 [H]/N=C(c1....
175 1O2P - 972 C18 H19 Cl N4 O2 CC(C)COc1c....
176 1K1I Kd = 264 nM FD1 C26 H28 N4 O5 S [H]/N=C(c1....
177 1GJ6 Ki = 0.23 uM 132 C21 H17 Cl N3 O c1ccc(cc1)....
178 3LJO Kd = 239 nM 11U C21 H31 N5 O2 [H]/N=C(/c....
179 1O2Y Ki = 1.4 uM 847 C18 H13 Br N4 O5 c1cc2c(cc1....
180 6SVN - BEN C7 H8 N2 [H]/N=C(c1....
181 1O31 Ki = 1.8 uM 801 C13 H11 N5 O c1cc(c(nc1....
182 2BY5 - BAM C7 H9 N2 c1ccc(cc1)....
183 1XUI - BAO C17 H14 N8 O c1cc2c(cc1....
184 1C5T Ki = 80 uM ESP C8 H8 N3 S c1cc2cc(sc....
185 1EB2 Ki = 16 nM BPO C28 H28 N4 O3 [H]/N=C(c1....
186 6SVB - BEN C7 H8 N2 [H]/N=C(c1....
187 1O2K Ki = 0.12 uM 656 C18 H20 N4 O2 CC(C)COc1c....
188 5LGO - 6VZ C27 H36 N6 O4 CNC(=O)[C@....
189 1GI0 - BMZ C14 H13 N4 O c1ccc(c(c1....
190 1V2P Ki = 18.45 uM ANH C20 H24 N4 O5 S Cc1ccc(cc1....
191 1TPS ic50 = 10 nM OSL DLE THR ARG GLU LEU YNM VAL n/a n/a
192 1N6Y - ABN C7 H9 N c1ccc(cc1)....
193 1O34 Ki = 1.8 uM 801 C13 H11 N5 O c1cc(c(nc1....
194 6SUX - BEN C7 H8 N2 [H]/N=C(c1....
195 2ZDL - 45U C20 H28 N4 O3 [H]/N=C(/c....
196 1PPH Ki = 1.2 uM 0ZG C22 H28 N4 O3 S [H]/N=C(/c....
197 2G5N - 23M C16 H15 N3 [H]/N=C(c1....
198 1G3D Ki = 2.8 uM 108 C11 H15 N3 O3 C[C@@H](C(....
199 5MOO Kd = 48.5 mM WOT C6 H8 N c1ccc(cc1)....
200 1O2U Ki = 1.4 uM 847 C18 H13 Br N4 O5 c1cc2c(cc1....
201 1O2R - CR9 C21 H23 F N4 O2 C[C@H]1CCC....
202 3QK1 - BEN C7 H8 N2 [H]/N=C(c1....
203 6SVX - BEN C7 H8 N2 [H]/N=C(c1....
204 5MNH Kd = 20.7 uM BAM C7 H9 N2 c1ccc(cc1)....
205 6B6P - BEN C7 H8 N2 [H]/N=C(c1....
206 3T29 - BEN C7 H8 N2 [H]/N=C(c1....
207 6EAT - CYS THR LYS SER ILE PRO PRO GLN CYS n/a n/a
208 1O2H Ki = 0.068 uM CR3 C20 H21 N3 O2 c1cc(c(c(c....
209 1QB9 Ki = 36 nM 806 C31 H31 N5 O [H]/N=C(/C....
210 2BLW - BEN C7 H8 N2 [H]/N=C(c1....
211 1O3B Ki = 0.074 uM 780 C20 H16 N4 O c1ccc(cc1)....
212 1O2Z Ki = 0.78 uM 312 C25 H20 N4 O6 COc1ccccc1....
213 1K1L Kd = 125 nM FD3 C24 H27 N5 O3 S [H]/N=C(/c....
214 1O2O Ki = 0.44 uM 950 C18 H19 F N4 O2 CC(C)COc1c....
215 1C1Q - BAI C16 H14 N6 c1ccc2c(c1....
216 1F0U Ki = 69 nM RPR C27 H30 N4 O3 C[C@H]([C@....
217 1C2G - BAH C17 H18 N8 O2 c1cc2c(cc1....
218 1O37 Ki = 0.15 uM 653 C22 H22 N5 O c1ccc(cc1)....
219 1O3F Ki = 0.011 uM 696 C21 H17 N3 O c1ccc(cc1)....
220 1JIR - AML C5 H13 N CCCCCN
221 1O2N Ki = 0.81 uM 762 C20 H15 Cl N4 O c1ccc(cc1)....
222 1O3O - 785 C15 H11 F3 N4 O2 c1cc2c(cc1....
223 1CE5 Ki = 18.4 uM BEN C7 H8 N2 [H]/N=C(c1....
224 5MNB Kd = 3.3 mM 2AP C5 H7 N2 c1cc[nH+]c....
225 6DZF - BEN C7 H8 N2 [H]/N=C(c1....
226 5LH8 - 6WH C31 H38 N6 O3 COc1cc(ccc....
227 2ZHD - 12U C22 H33 N5 O2 [H]/N=C(/c....
228 1O2J Ki = 0.12 uM 656 C18 H20 N4 O2 CC(C)COc1c....
229 1AQ7 ic50 = 0.9 uM 34H DIL XPR AG2 n/a n/a
230 1O3K Ki = 0.17 uM 334 C15 H13 Br N4 O Cc1cc(c(c(....
231 2G5V - 22M C16 H15 N3 [H]/N=C(c1....
232 1Y5U Kd = 0.22 uM TL4 C20 H22 N4 O4 c1cc(cc(c1....
233 6SVI - BEN C7 H8 N2 [H]/N=C(c1....
234 1J8A - BEN C7 H8 N2 [H]/N=C(c1....
235 6B6Q - BEN C7 H8 N2 [H]/N=C(c1....
236 1QB1 Ki = 170 nM 974 C28 H27 F2 N6 O5 Cn1ccnc1c2....
237 1O2W Ki = 1.4 uM 847 C18 H13 Br N4 O5 c1cc2c(cc1....
238 1XUF Ki = 0.09 uM BAZ C17 H16 N8 Zn [H]/N=C(c1....
239 1QBN Ki = 1400 nM 688 C22 H17 N5 O5 c1cc(cc(c1....
240 1O33 Ki = 1.8 uM 801 C13 H11 N5 O c1cc(c(nc1....
241 1V2O Ki = 18.45 uM ANH C20 H24 N4 O5 S Cc1ccc(cc1....
242 1C1N - BAM C7 H9 N2 c1ccc(cc1)....
243 1UTN Kd = 0.321 mM ABN C7 H9 N c1ccc(cc1)....
244 6SVD - BEN C7 H8 N2 [H]/N=C(c1....
245 6T0P Ki = 62 uM M6Q C20 H25 N5 O2 c1ccc(cc1)....
246 6SVW - BEN C7 H8 N2 [H]/N=C(c1....
247 4NA8 Ki = 1.5 nM 1T6 C31 H28 N4 O3 [H]/N=C(/c....
248 5WB6 Ki = 0.02 nM 9ZM C31 H26 Cl F N10 O4 COC(=O)Nc1....
249 5Q0H Ki = 12 nM 9F1 C27 H26 Cl F2 N5 O4 Cc1cc(c(c(....
250 5TKT Ki = 3.2 nM 7DS C28 H26 Cl N9 O4 COC(=O)Nc1....
251 4CRG - J4X C22 H18 N6 O [H]/N=C(c1....
252 5EXL Ki = 3.7 nM 5SS C28 H31 N5 O2 c1ccc(cc1)....
253 6TS5 ic50 = 0.003 uM NW2 C27 H29 N O5 CC(C)c1cc(....
254 6VLU Ki = 149.1 nM R2Y C27 H37 F2 N5 O2 CC(C)C[C@H....
255 5E2O Ki = 2 nM 5JM C26 H21 Cl N6 O4 c1ccc(cc1)....
256 4CRB Ki = 0.027 uM 7P0 C28 H24 Cl N7 O4 c1ccc(cc1)....
257 6TS6 ic50 = 0.004 uM NW5 C27 H26 N2 O4 CC(C)(C#N)....
258 5TKS Ki = 68 nM 7DL C29 H30 Cl2 N8 O3 COC(=O)Nc1....
259 5QTY Ki = 2.5 nM QLJ C32 H33 Cl N8 O5 CCOC(=O)[C....
260 5Q0E Ki = 0.69 nM 9FD C29 H30 Cl N9 O4 C[C@H]1CCC....
261 4CRE - MVN C10 H8 Cl N O CC1=CC(=O)....
262 4CRA Ki = 0.06 uM XJ8 C29 H25 N5 O4 c1ccc(cc1)....
263 1ZHR - BEN C7 H8 N2 [H]/N=C(c1....
264 5E2P Ki = 1.6 nM 7P0 C28 H24 Cl N7 O4 c1ccc(cc1)....
265 3BG8 - BEN C7 H8 N2 [H]/N=C(c1....
266 4X6P Ki = 5 nM 3YU C28 H23 Cl N10 O c1ccc(cc1)....
267 5Q0D Ki = 1 nM 9EY C27 H26 Cl N9 O4 COC(=O)Nc1....
268 4X6O Ki = 1.9 nM 3Y4 C29 H26 Cl2 N8 O3 COC(=O)Nc1....
269 5EXN Ki = 23 nM 5SU C31 H26 Cl N7 O3 COC(=O)Nc1....
270 4CR9 Ki = 80 uM OTW C10 H11 N3 Cc1cc(nc2c....
271 6TS4 ic50 = 2.8 uM J7B C22 H20 N2 O3 c1ccc(c(c1....
272 6USY Ki = 0.0004 uM QGS C28 H28 N2 O4 CC(C)c1cc(....
273 4CRC Ki = 0.0019 uM OTM C26 H21 Cl N10 O2 c1ccc(cc1)....
274 5QCL Ki = 11 nM BUY C27 H21 Cl N6 O4 c1ccc2c(c1....
275 1ZHM - BEN C7 H8 N2 [H]/N=C(c1....
276 5EXM Ki = 6.3 nM 5ST C29 H34 N4 O3 COC(=O)Nc1....
277 4TY7 Ki = 0.3 nM 39F C26 H30 Cl N7 O c1ccc(cc1)....
278 5QTT Ki = 3.4 nM QEY C30 H29 Cl F N7 O4 C[C@@H]1CC....
279 6W50 Ki = 0.3 nM SWP C31 H29 Cl F2 N4 O4 C[C@@H]1CC....
280 5QQP Ki = 5.3 nM NR7 C29 H30 Cl N5 O4 COC(=O)Nc1....
281 6C0S Ki = 89 nM EEJ C31 H31 Cl2 N9 O4 CC(=O)N1CC....
282 4CRF Ki = 0.0005 uM R9B C29 H23 Cl N4 O5 c1ccc(cc1)....
283 5QCN Ki = 6 nM BVM C36 H34 Cl N7 O7 CCOC(=O)[C....
284 6VLV Ki = 5.33 nM R3A C19 H25 Cl N6 O4 S [H]/N=C(/N....
285 5QTV Ki = 1.1 nM QLS C28 H27 Cl F3 N9 O3 COC(=O)Nc1....
286 4X6M Ki = 5.8 nM 3Y3 C27 H26 Cl2 N8 O c1ccc(cc1)....
287 5QTW Ki = 0.46 nM QLM C29 H30 Cl N9 O5 COC(=O)[C@....
288 4CR5 Ki = 70 uM 0TU C9 H6 Cl N O c1cc2c(cc1....
289 4CRD Ki = 0.08 uM OTJ C22 H22 Cl2 N8 O3 COC(=O)Nc1....
290 5QCM Ki = 110 nM BVJ C28 H23 Cl F N7 O4 COC(=O)Nc1....
291 5NB6 ic50 = 0.5 uM 8S2 C22 H21 F3 N6 O4 c1ccc2c(c1....
292 6FTY - E7H C20 H24 N4 O2 c1cc2c(cc(....
293 6QMR ic50 = 0.012 uM J6T C23 H23 N O4 c1ccc(c(c1....
294 5NAW ic50 = 0.05 uM 8RZ C23 H20 F3 N5 O4 c1ccc2c(c1....
295 5MT0 Kd ~ 500 uM QJS C19 H15 F N2 O3 c1ccc(cc1)....
296 6FUG Kd = 50 uM E85 C18 H17 N7 O c1cc(cc(c1....
297 5NAR ic50 = 0.5 uM 8RW C22 H20 F3 N5 O4 c1ccc2c(c1....
298 5FBE ic50 = 14 uM 5W5 C22 H22 F3 N3 O5 COC(=O)c1c....
299 6FUH Kd = 170 uM E88 C20 H23 N5 O2 CC(C)[C@@H....
300 5FBI Kd = 1600 uM 5WD C17 H14 N2 O4 c1cc(cc(c1....
301 6QMT ic50 = 0.12 uM J7B C22 H20 N2 O3 c1ccc(c(c1....
302 6FUT Kd = 20 uM E82 C24 H24 N2 O c1ccc2c(c1....
303 6FUJ ic50 = 120 uM E8B C18 H22 N2 O CC(C)CC(=O....
304 5FCK Kd = 0.006 uM 5WC C23 H22 Cl F N6 O3 C[C@H](c1c....
305 5NB7 ic50 = 0.006 uM 8NQ C21 H19 Br N6 O3 c1ccc2c(c1....
306 5MT4 Kd ~ 500 uM M7O C15 H14 N2 O3 c1ccc(cc1)....
307 5NBA ic50 = 0.05 uM 8S5 C22 H19 F4 N5 O4 c1ccc2c(c1....
308 6FUI Kd = 35 uM E7W C22 H25 N5 O2 c1ccc2c(c1....
309 6FTZ Kd = 1000 uM E7E C17 H16 N4 O2 c1cc(cc(c1....
310 6A8N Ki = 6.8 nM CYS PRO ALA TYR SER ARG TYR ILE GLY CYS n/a n/a
311 1ELC - 0Z3 C26 H34 F3 N4 O3 CC(C)c1ccc....
312 1ELD Ki = 0.2 uM 0Z0 C21 H19 F6 N3 O3 NULL
313 7EST - 0Z2 C18 H21 F6 N3 O3 CC(C)C[C@@....
314 2BD4 - LYS TYR PRO PHE VAL GLU PRO ILE n/a n/a
315 1ELB Ki = 70 nM 0Z4 C23 H36 F3 N4 O3 CC(C)C[C@@....
316 6TH7 ic50 = 1.18 nM O4Q 5XU ABA ILE ABA VAL N9K PHA AA4 n/a n/a
317 1ELE Ki = 0.14 uM 0QN C17 H19 F6 N3 O3 NULL
318 4GVU ic50 = 30 nM 6NA GLN THR DBU GLJ PHE YNM VAL n/a n/a
319 1NES - ACE ALA PRO ALA n/a n/a
320 2BDB - ALA ALA n/a n/a
321 1BMA Ki = 26 uM 0QH C27 H36 F3 N4 O3 NULL
322 2EST - 2Z5 C18 H23 F6 N4 O3 NULL
323 1ELA Ki = 0.44 uM 0Z1 C22 H32 F3 N4 O3 CC(C)c1ccc....
324 1QR3 ic50 = 0.26 uM ALQ CIR THR DBU GLJ PHE TYJ VAL n/a n/a
325 1BIT - BEN C7 H8 N2 [H]/N=C(c1....
326 1HJ8 - BAM C7 H9 N2 c1ccc(cc1)....
327 1UTL Ka = 293 M^-1 PRA C9 H13 N c1ccc(cc1)....
328 2TBS - BEN C7 H8 N2 [H]/N=C(c1....
329 2ZPQ - BEN C7 H8 N2 [H]/N=C(c1....
330 1UTJ Kd = 0.144 mM ABN C7 H9 N c1ccc(cc1)....
331 1UTM Ka = 243 M^-1 PEA C8 H12 N c1ccc(cc1)....
332 1MBQ - BEN C7 H8 N2 [H]/N=C(c1....
333 2ZPS - BEN C7 H8 N2 [H]/N=C(c1....
334 2ZPR - BEN C7 H8 N2 [H]/N=C(c1....
335 1L2E - BEN C7 H8 N2 [H]/N=C(c1....
336 3VFE - 0HL C26 H26 N4 O4 S3 [H]/N=C(c1....
337 6QH9 - J3B C13 H16 N4 O2 [H]/N=C(/c....
338 6QFH ic50 = 1.38 uM J08 C23 H22 N6 O [H]/N=C(/c....
339 6QHB - J2W C15 H15 N3 O3 [H]/N=C(/c....
340 6SKC - BEN C7 H8 N2 [H]/N=C(c1....
341 1LO6 - BEN C7 H8 N2 [H]/N=C(c1....
342 6QFF ic50 = 2.04 uM J08 C23 H22 N6 O [H]/N=C(/c....
343 6QHC - 135 C14 H13 N3 O2 [H]/N=C(c1....
344 4D8N ic50 = 1.8 uM 0HM C24 H24 N5 O2 c1ccc(cc1)....
345 6QFG ic50 = 3.01 uM J08 C23 H22 N6 O [H]/N=C(/c....
346 6QHA - J2Q C16 H17 N3 O3 [H]/N=C(/c....
347 3P8G - BEN C7 H8 N2 [H]/N=C(c1....
348 1EAX - BEN C7 H8 N2 [H]/N=C(c1....
349 2GV6 Ki = 0.046 uM 730 C28 H35 N7 O3 S [H]/N=C(c1....
350 4R0I Ki = 0.3 uM 3KM C27 H33 N5 O4 S [H]/N=C(c1....
351 4O97 Ki = 3 nM NTX C29 H34 N6 O3 [H]/N=C(N)....
352 2GV7 Ki = 0.014 uM 672 C36 H54 N8 O4 S [H]/N=C(c1....
353 4O9V Ki = 10 nM NT4 C27 H30 N6 O3 [H]/N=C(N)....
354 1IAU Ki = 80 nM ACE ILE GLU PRO ASJ n/a n/a
355 1ANE - BEN C7 H8 N2 [H]/N=C(c1....
356 1J16 Ki = 143 uM BEN C7 H8 N2 [H]/N=C(c1....
357 1J14 Ki = 32.2 uM BEN C7 H8 N2 [H]/N=C(c1....
358 1BRA Ki = 15000 uM BEN C7 H8 N2 [H]/N=C(c1....
359 1J15 Ki = 143 uM BEN C7 H8 N2 [H]/N=C(c1....
360 1TRM - BEN C7 H8 N2 [H]/N=C(c1....
361 1J17 Ki = 6.05 uM ZEN C25 H27 Cl N4 O3 S c1cc(cc2c1....
362 1ANC - BEN C7 H8 N2 [H]/N=C(c1....
363 1QL9 Ki = 4.45 uM ZEN C25 H27 Cl N4 O3 S c1cc(cc2c1....
364 1DPO - BEN C7 H8 N2 [H]/N=C(c1....
365 1AND - BEN C7 H8 N2 [H]/N=C(c1....
366 1W0Z Ki = 21 nM SI1 C18 H29 N5 O5 S [H]/N=C(c1....
367 4ZHL Kd = 0.0147 uM CYS PRO ALA TYR SER ARG TYR ILE GLY CYS n/a n/a
368 2VIV ic50 = 520 nM VG2 C22 H28 Cl N3 O2 Cc1cc(cc(c....
369 1SC8 Ki = 0.036 uM 2IN C20 H25 N5 O5 S c1ccc(cc1)....
370 1OWE Ki = 0.631 uM 675 C18 H15 N3 O [H]/N=C(/c....
371 4X1Q - CYS PRO ALA TYR SER ARG TYR LEU ASP CYS n/a n/a
372 2VIP ic50 = 5.2 uM L1R C18 H20 Cl2 N2 O3 CC(C)Oc1cc....
373 5ZAF Ki = 166 nM 28I C16 H21 N7 O2 [H]/N=C(N)....
374 1SQT Ki = 0.63 uM UI3 C16 H16 N4 O3 S [H]/N=C(/c....
375 1W13 Ki = 2 nM SM1 C21 H28 N6 O5 S [H]/N=C(/N....
376 1OWH Ki = 40 nM 239 C19 H18 N4 O [H]/N=C(/c....
377 1EJN Ki = 2.4 uM AGB C19 H27 N5 O [H]/N=C(/N....
378 4ZHM Kd = 0.00081 uM MRZ CYS PRO ALA TYR SER ALA TYR ILE GLY CYS n/a n/a
379 2VIN ic50 > 1 mM 505 C11 H17 N O Cc1cccc(c1....
380 5ZA8 Ki = 508 nM 27I C16 H23 N9 O [H]/N=C(/N....
381 5ZA7 Ki = 1356 nM HMX C12 H18 Cl N7 O C1CCCN(CC1....
382 4X0W - MRZ CYS PRO ALA TYR SER DAL TYR LEU ASP CYS n/a n/a
383 1U6Q - 745 C20 H18 N2 [H]/N=C(/c....
384 5ZA9 Ki = 183 nM 50I C20 H23 N7 O2 [H]/N=C(/N....
385 2VIQ ic50 = 1.3 uM D55 C21 H28 N2 O4 CCOc1ccc(c....
386 4X1P - CYS PRO ALA TYR SER DAL TYR LEU ASP CYS MRZ n/a n/a
387 6NMB Ki = 2.01 mM AMH C8 H15 N O2 C1CC(CCC1C....
388 5ZAG Ki = 108 nM 94I C16 H21 N9 O [H]/N=C(N)....
389 5ZC5 Ki = 88 nM 09I C20 H22 F N7 O2 [H]/N=C(/N....
390 1VJ9 Ki = 0.028 uM 5IN C28 H33 N5 O6 S c1ccc(cc1)....
391 1F5K Ki = 180 uM BAM C7 H9 N2 c1ccc(cc1)....
392 5ZAE Ki = 156 nM EAU C16 H21 N7 O2 [H]/N=C(/N....
393 1OWD Ki = 6.3 nM 497 C23 H24 N4 O CC[C@H]1CN....
394 2VNT Ki = 9.9 nM QGG C15 H16 Cl N5 O4 S c1cc2c(cc1....
395 2VIO ic50 = 40 uM L1O C9 H9 Cl2 N O3 c1c(cc(c(c....
396 1F5L Ki = 5.3 uM AMR C6 H8 Cl N7 O c1(c(nc(c(....
397 5ZAJ Ki = 42 nM 32I C18 H25 N9 O3 [H]/N=C(/N....
398 2R2W Ki = 34 uM 4PG C15 H15 N3 O [H]/N=C(/N....
399 2VIW ic50 = 72 nM D56 C24 H32 Cl N3 O3 CCOc1c(cc(....
400 1W11 Ki = 6 nM SK1 C21 H27 N5 O5 S [H]/N=C(c1....
401 1SQA Ki = 0.00062 uM UI1 C23 H21 N7 O c1cnc(nc1)....
402 1VJA Ki = 0.02 uM 7IN C21 H27 N5 O6 S c1ccc(cc1)....
403 1SQO Ki = 0.035 uM UI2 C15 H13 N5 c1cc2ccc(c....
404 1GDN - GLY ALA LYS n/a n/a
405 1FY5 - GLY ALA LYS n/a n/a
406 1FY4 - GLY ALA ARG n/a n/a
407 1PQ8 - GLY GLY ARG n/a n/a
408 1FN8 - GLY ALA ARG n/a n/a
409 1PQ7 - ARG C6 H15 N4 O2 C(C[C@@H](....
410 1PQ5 - ARG C6 H15 N4 O2 C(C[C@@H](....
411 1H4W Ki = 22 uM BEN C7 H8 N2 [H]/N=C(c1....
412 5TP0 Ki = 3.66 uM BRN C14 H15 N7 c1cc(ccc1C....
413 1T32 Ki = 38 nM OHH C40 H35 N2 O6 P CN(C1CCN(C....
414 4K60 ic50 = 570 uM 1P8 C8 H6 Br N O c1cc2c(cc1....
415 1T31 Ki = 2.3 nM OHH C40 H35 N2 O6 P CN(C1CCN(C....
416 4K5Z - 1P7 C8 H6 Cl N O c1cc2c(cc1....
417 3N7O Ki = 72 nM N7O C19 H15 Cl F2 N O3 P S C[P@@](=O)....
418 3S0N ic50 = 180 nM 0BB C21 H20 N2 O3 S Cc1cccc2c1....
419 5YJM Kd = 0.000000064 M 8W3 C30 H32 Cl N5 O6 CC[C@H](c1....
420 4K2Y ic50 = 470 uM ES2 C8 H6 Cl N O c1cc2c(cc1....
421 5YJP ic50 = 0.24 uM 8W6 C26 H31 Cl N4 O6 CC[C@H](c1....
422 4K69 ic50 = 0.04 uM 1P9 C22 H22 Br N3 O4 CCC[C@@H](....
423 1OSS Ki = 16.4 uM BEN C7 H8 N2 [H]/N=C(c1....
424 3BEU - BEN C7 H8 N2 [H]/N=C(c1....
425 5XWL - ACE THR ARG GLU n/a n/a
426 5XWJ - ACE THR ARG GLU n/a n/a
427 1V6D - PRO ASP AIB LEU AIB LEU ALA TBF NME n/a n/a
428 1YF4 Ki = 5 nM CYS TYR PHE GLN ASN CYS PRO ARG GLY NH2 n/a n/a
429 1S6H - 4BZ C8 H10 N2 O [H]/N=C(c1....
430 1S83 - 4HA C4 H12 N O C(CCO)C[NH....
431 1S5S - PG3 C4 H12 N3 O C(CNC(=[NH....
432 5A09 ic50 = 3.5 nM JJD C23 H18 F3 N3 O4 CC1=C([C@H....
433 5A8X ic50 = 6.5 nM IUY C24 H20 F3 N4 O2 CCOC(=O)C1....
434 5ABW ic50 = 17 nM WQQ C26 H24 Cl N3 O5 S Cc1c(c(on1....
435 5A8Y ic50 = 0.17 nM VBM C23 H16 F3 N7 O2 CC1=C([C@H....
436 5A0B ic50 = 5 nM JJX C29 H29 F3 N6 O2 CC1=C([C@H....
437 5A8Z ic50 = 28 nM IUL C21 H16 F3 N5 O2 CN1CC2=C([....
438 3Q77 ic50 = 6 nM 2HY C22 H18 F3 N3 O4 CC1=C([C@H....
439 5A0C ic50 = 0.54 nM JJV C21 H15 F3 N4 O3 S CC1=C([C@H....
440 5A0A Ki = 15 nM JJS C20 H15 F3 N4 O2 CC1=C([C@H....
441 2AIQ - BEN C7 H8 N2 [H]/N=C(c1....
442 2OQ5 - BEN C7 H8 N2 [H]/N=C(c1....
443 5F03 - 5TA C24 H20 Cl N3 O3 c1cc(cc(c1....
444 2ZA5 Ki = 3.7 nM 2FF C26 H24 N2 O3 c1ccc(cc1)....
445 2FPZ Ki = 110 uM 270 C7 H7 N3 C1=CC2=NC(....
446 2BM2 Ki = 15 nM PM2 C26 H29 N3 O c1ccc(cc1)....
447 3V7T Ki = 62 nM 0GX C23 H28 Br F N2 O2 S CCCOc1c(c(....
448 2ZEB - 11M C23 H24 N2 O2 S2 CSc1c2cccc....
449 4A6L Ki = 10 nM P43 C25 H23 F N2 O2 c1ccc(c(c1....
450 2ZEC - 11N C22 H24 N2 O2 c1ccc(cc1)....
451 4NFE - BEN C7 H8 N2 [H]/N=C(c1....
452 2ANW - BAM C7 H9 N2 c1ccc(cc1)....
453 2ANY - BAM C7 H9 N2 c1ccc(cc1)....
454 5TJX - GBT C29 H33 N7 O3 Cc1c2c(cc(....
455 6O1S - 7SD C23 H25 N7 O Cc1cc(nc(c....
456 6T7P Ki = 0.97 uM MU8 C26 H24 Cl N3 O3 c1ccc(cc1)....
457 6QFE ic50 = 0.08 uM J08 C23 H22 N6 O [H]/N=C(/c....
458 6B74 - BEN C7 H8 N2 [H]/N=C(c1....
459 1A0J - BEN C7 H8 N2 [H]/N=C(c1....
460 2ZGJ - SER SER GLY LYS VAL PRO LEU SER n/a n/a
461 2ZGH - SER SER GLY LYS VAL PRO LEU n/a n/a
462 2BDG - PBZ C7 H10 N3 c1cc(ccc1C....
463 5Y9L ic50 = 1.9 uM 8R3 C24 H28 Cl N5 O5 CN(C)/N=C1....
464 5YJK ic50 = 0.82 uM 8VX C24 H30 Cl N5 O5 S CN(C)/N=C1....
465 5FAH ic50 = 0.7 uM 5VT C26 H29 N3 O3 COc1ccc(cc....
466 3TJV - PRO THR SER TYR ALA GLY ASP ASP SER GLY n/a n/a
467 6AHS ic50 = 1.5 uM 9YO C19 H18 Cl N3 O2 S Cc1ccc2c(c....
468 5ZFI ic50 = 1.2 uM 9C9 C26 H29 Cl2 N7 O2 Cn1cc(cn1)....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: PBZ; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 PBZ 1 1
2 BAM 0.428571 0.85
Similar Ligands (3D)
Ligand no: 1; Ligand: PBZ; Similar ligands found: 1220
No: Ligand Similarity coefficient
1 HBD 1.0000
2 PHB 1.0000
3 1Y6 1.0000
4 AC6 1.0000
5 NPO 1.0000
6 826 1.0000
7 PAB 1.0000
8 4MA 1.0000
9 P72 1.0000
10 SW7 0.9996
11 Z82 0.9994
12 174 0.9958
13 BEZ 0.9798
14 4BZ 0.9796
15 HBA 0.9790
16 ANN 0.9770
17 E5X 0.9768
18 PBC 0.9760
19 HDH 0.9759
20 4P5 0.9755
21 NCA 0.9749
22 BEN 0.9747
23 4NC 0.9734
24 DHB 0.9731
25 AMH 0.9728
26 PNZ 0.9716
27 JLZ 0.9704
28 FHB 0.9697
29 4VP 0.9695
30 6PC 0.9695
31 NIO 0.9694
32 IPB 0.9693
33 P9P 0.9693
34 QSB 0.9693
35 BHA 0.9690
36 XX2 0.9689
37 FA0 0.9684
38 93K 0.9683
39 2HO 0.9682
40 4A3 0.9681
41 UNU 0.9679
42 IHB 0.9679
43 OTR 0.9675
44 DOB 0.9674
45 9TW 0.9670
46 INO 0.9670
47 FBA 0.9667
48 NNO 0.9665
49 4JM 0.9663
50 BPN 0.9663
51 MYJ 0.9662
52 NTN 0.9661
53 4M0 0.9657
54 5CU 0.9653
55 3HM 0.9650
56 5NU 0.9649
57 CHB 0.9649
58 SAN 0.9648
59 GUA 0.9647
60 AC0 0.9646
61 NBZ 0.9644
62 PZA 0.9638
63 4NM 0.9633
64 BZ3 0.9632
65 SS1 0.9630
66 BNS 0.9629
67 SN4 0.9623
68 FBS 0.9620
69 FQI 0.9613
70 BE7 0.9613
71 AX7 0.9613
72 YCP 0.9611
73 4J8 0.9611
74 CFI 0.9611
75 TSU 0.9610
76 JAE 0.9608
77 QSC 0.9605
78 FCR 0.9604
79 5OB 0.9602
80 4ZA 0.9600
81 ABV 0.9590
82 4FA 0.9583
83 4JL 0.9581
84 4WL 0.9577
85 VGL 0.9568
86 H8N 0.9557
87 AAS 0.9556
88 ISZ 0.9555
89 OAA 0.9554
90 259 0.9552
91 MLT 0.9551
92 2MI 0.9548
93 PHU 0.9547
94 AEF 0.9546
95 M58 0.9538
96 S2G 0.9536
97 14O 0.9536
98 AMS 0.9535
99 2K4 0.9534
100 F60 0.9531
101 JZ7 0.9530
102 5H1 0.9529
103 270 0.9525
104 03V 0.9523
105 RSO 0.9521
106 BHO 0.9521
107 XM0 0.9521
108 DHR 0.9519
109 2AQ 0.9519
110 SRT 0.9518
111 HIO 0.9514
112 TYL 0.9514
113 TH7 0.9513
114 5MI 0.9512
115 4FS 0.9509
116 FBB 0.9508
117 C2B 0.9508
118 NIZ 0.9507
119 OCH 0.9507
120 P92 0.9506
121 H42 0.9502
122 ES5 0.9500
123 XQ0 0.9500
124 COU 0.9499
125 5XC 0.9498
126 FAN 0.9498
127 M4T 0.9497
128 TPA 0.9494
129 JB5 0.9493
130 IT2 0.9489
131 6RQ 0.9488
132 OK7 0.9484
133 FBM 0.9483
134 11S 0.9480
135 ET2 0.9477
136 HMH 0.9475
137 717 0.9474
138 K2T 0.9472
139 3ID 0.9472
140 NPY 0.9468
141 YRL 0.9468
142 FEH 0.9465
143 3PF 0.9465
144 ODO 0.9463
145 6AI 0.9462
146 173 0.9460
147 SAL 0.9457
148 MSR 0.9456
149 5WV 0.9455
150 I1E 0.9454
151 D48 0.9454
152 TTL 0.9450
153 5MB 0.9446
154 8WO 0.9445
155 DYA 0.9445
156 DMD 0.9445
157 BE2 0.9445
158 XYL 0.9443
159 RB5 0.9443
160 M3H 0.9439
161 I3E 0.9439
162 BZX 0.9439
163 14J 0.9436
164 HC4 0.9435
165 PZM 0.9434
166 QUZ 0.9434
167 0HO 0.9431
168 UGC 0.9430
169 L99 0.9428
170 MS9 0.9428
171 AMC 0.9424
172 G3E 0.9424
173 SE2 0.9423
174 CLW 0.9421
175 J5I 0.9419
176 7WG 0.9419
177 1M2 0.9418
178 PIY 0.9417
179 ES2 0.9417
180 0HN 0.9416
181 1PT 0.9415
182 36R 0.9413
183 3A9 0.9412
184 5QY 0.9409
185 FK1 0.9408
186 VGD 0.9408
187 HY1 0.9407
188 GLU 0.9407
189 H4N 0.9404
190 ES6 0.9403
191 F9P 0.9402
192 4SV 0.9402
193 KOJ 0.9399
194 67N 0.9399
195 SYV 0.9399
196 2FY 0.9395
197 ES9 0.9395
198 XIY 0.9393
199 LMR 0.9392
200 2BG 0.9388
201 ABI 0.9388
202 6NT 0.9388
203 1P8 0.9388
204 PIM 0.9387
205 3HB 0.9387
206 2CK 0.9386
207 GJZ 0.9386
208 SKM 0.9385
209 2A9 0.9381
210 CXF 0.9380
211 LDP 0.9379
212 4AA 0.9379
213 K34 0.9379
214 5VM 0.9378
215 LNR 0.9377
216 CPZ 0.9377
217 FYU 0.9375
218 KJH 0.9375
219 3NT 0.9375
220 KKN 0.9374
221 MXN 0.9373
222 EHM 0.9370
223 3U4 0.9369
224 PAC 0.9369
225 8ZE 0.9367
226 ES7 0.9367
227 3NY 0.9367
228 6NI 0.9367
229 2RH 0.9366
230 2ZM 0.9365
231 PRO 0.9364
232 PMB 0.9363
233 MQN 0.9362
234 WCE 0.9362
235 2HU 0.9360
236 COI 0.9360
237 1SA 0.9359
238 JA8 0.9359
239 C21 0.9359
240 4JT 0.9357
241 DHK 0.9356
242 4XR 0.9356
243 7W1 0.9356
244 TZF 0.9356
245 QWN 0.9356
246 4CS 0.9356
247 2FT 0.9355
248 GDE 0.9354
249 5NI 0.9354
250 AKG 0.9353
251 3AB 0.9352
252 JKE 0.9351
253 ESP 0.9348
254 VNJ 0.9346
255 FB2 0.9346
256 7WV 0.9345
257 1F1 0.9344
258 TIU 0.9343
259 ISN 0.9342
260 F4E 0.9342
261 CN0 0.9341
262 LCN 0.9339
263 12Q 0.9339
264 SNU 0.9338
265 HHH 0.9337
266 BZ2 0.9337
267 8GC 0.9336
268 OVV 0.9336
269 8NY 0.9333
270 MZW 0.9332
271 BP9 0.9332
272 X0V 0.9331
273 JAW 0.9331
274 5QX 0.9329
275 ASO 0.9329
276 4JQ 0.9329
277 HMU 0.9328
278 ZXD 0.9327
279 J9Q 0.9326
280 C1M 0.9325
281 JBE 0.9325
282 AL0 0.9324
283 M4S 0.9323
284 54D 0.9323
285 NOY 0.9320
286 MRZ 0.9318
287 M1A 0.9318
288 LQ2 0.9317
289 IFL 0.9316
290 DE5 0.9314
291 1WD 0.9312
292 L14 0.9311
293 GAB 0.9310
294 SHA 0.9309
295 PYF 0.9308
296 IFP 0.9307
297 DEN 0.9307
298 1DJ 0.9306
299 CTL 0.9306
300 6FZ 0.9305
301 MNN 0.9305
302 AHR 0.9305
303 E7Z 0.9303
304 QXW 0.9302
305 EKZ 0.9301
306 4JU 0.9301
307 HX3 0.9300
308 4SX 0.9298
309 BCU 0.9297
310 FPI 0.9297
311 ABN 0.9296
312 HBX 0.9295
313 RBJ 0.9292
314 6M9 0.9291
315 8H8 0.9290
316 3OC 0.9290
317 F9Y 0.9289
318 7W4 0.9288
319 QSH 0.9287
320 4NB 0.9286
321 5HN 0.9286
322 4FH 0.9285
323 53C 0.9283
324 2MH 0.9283
325 24B 0.9278
326 4Z4 0.9276
327 NOJ 0.9275
328 SEP 0.9274
329 ICB 0.9274
330 IND 0.9274
331 TZC 0.9274
332 0TU 0.9273
333 86J 0.9271
334 4JC 0.9270
335 SYN 0.9269
336 CWJ 0.9269
337 SS2 0.9269
338 RBL 0.9268
339 N2I 0.9266
340 FGZ 0.9265
341 BDP 0.9265
342 BRT 0.9265
343 PEA 0.9264
344 36Y 0.9262
345 JZ5 0.9262
346 6M4 0.9261
347 IDM 0.9260
348 J9N 0.9260
349 NSP 0.9259
350 IV2 0.9255
351 3F0 0.9253
352 LT2 0.9252
353 4YO 0.9251
354 3BZ 0.9249
355 94W 0.9249
356 GYE 0.9248
357 FE DB1 0.9248
358 LDU 0.9247
359 HQT 0.9247
360 PY7 0.9246
361 BML 0.9241
362 LZ1 0.9241
363 BSX 0.9239
364 ZZT 0.9239
365 B57 0.9239
366 NDH 0.9239
367 NF3 0.9239
368 QY9 0.9238
369 2HQ 0.9238
370 BZI 0.9236
371 R8V 0.9234
372 SVN 0.9231
373 OKG 0.9229
374 SKA 0.9229
375 268 0.9228
376 FOA 0.9228
377 DGJ 0.9227
378 DBH 0.9227
379 SMV 0.9227
380 3HA 0.9226
381 RHU 0.9225
382 JDN 0.9224
383 NMJ 0.9224
384 N2Z 0.9223
385 A5E 0.9223
386 MR1 0.9222
387 TP5 0.9222
388 G4D 0.9221
389 IF7 0.9221
390 ASP 0.9221
391 JBN 0.9219
392 PKU 0.9218
393 G2F 0.9218
394 0RW 0.9218
395 F05 0.9218
396 FBJ 0.9213
397 PXL 0.9212
398 PZI 0.9212
399 0R1 0.9210
400 URS 0.9207
401 7N0 0.9206
402 KBZ 0.9206
403 EDG 0.9204
404 NBE 0.9204
405 9CL 0.9204
406 XUL 0.9204
407 5LA 0.9204
408 TGX 0.9204
409 A29 0.9201
410 15E 0.9201
411 2IT 0.9200
412 GGL 0.9200
413 PYC 0.9199
414 1DV 0.9198
415 60P 0.9198
416 265 0.9197
417 3M0 0.9196
418 XBT 0.9195
419 KJU 0.9195
420 4JP 0.9193
421 4CH 0.9192
422 J9T 0.9192
423 PCR 0.9191
424 ZBT 0.9191
425 DIN 0.9191
426 HIS 0.9190
427 DS0 0.9189
428 MPI 0.9189
429 RNO 0.9188
430 1AB 0.9187
431 BZF 0.9186
432 ESX 0.9186
433 GLC 0.9186
434 4HS 0.9185
435 PCA 0.9185
436 HLR 0.9183
437 XRG 0.9182
438 FBV 0.9181
439 PXY 0.9181
440 RNT 0.9180
441 LG4 0.9179
442 GAG 0.9179
443 FB1 0.9178
444 OGA 0.9177
445 DGN 0.9176
446 1MR 0.9176
447 SPA 0.9176
448 HQE 0.9172
449 4VY 0.9171
450 8K2 0.9170
451 GLN 0.9169
452 ASC 0.9168
453 A7N 0.9168
454 1DW 0.9167
455 FUD 0.9167
456 SNO 0.9166
457 RMN 0.9164
458 RAT 0.9163
459 QMP 0.9163
460 A7W 0.9163
461 TZL 0.9162
462 282 0.9161
463 MRY 0.9161
464 5GU 0.9160
465 FP1 0.9159
466 9EW 0.9159
467 4JN 0.9158
468 BGC 0.9157
469 EA1 0.9156
470 GVH 0.9156
471 JB8 0.9153
472 MAE 0.9153
473 R2B 0.9152
474 2PC 0.9152
475 J6W 0.9152
476 PLQ 0.9150
477 4HP 0.9148
478 NYL 0.9147
479 IFM 0.9147
480 PEP 0.9147
481 AEG 0.9144
482 PEL 0.9142
483 ADA 0.9142
484 RIB 0.9142
485 3QM 0.9142
486 AHB 0.9141
487 JZ9 0.9141
488 FPN 0.9140
489 UY7 0.9140
490 25R 0.9139
491 XYP 0.9139
492 E7S 0.9138
493 DGL 0.9136
494 NCT 0.9136
495 KDV 0.9136
496 DA1 0.9134
497 HYP 0.9133
498 TLA 0.9132
499 LXC 0.9132
500 OXZ 0.9130
501 KTA 0.9130
502 0CT 0.9130
503 KMT 0.9129
504 273 0.9129
505 OHG 0.9129
506 3DO 0.9128
507 GZL 0.9126
508 3SK 0.9123
509 RNS 0.9122
510 GBD 0.9122
511 GRO 0.9122
512 3DM 0.9120
513 GTR 0.9120
514 SMN 0.9118
515 GAL 0.9117
516 MRW 0.9117
517 8OZ 0.9116
518 1IT 0.9116
519 2HG 0.9116
520 069 0.9114
521 7MU 0.9113
522 0VT 0.9112
523 69O 0.9112
524 40E 0.9111
525 HHA 0.9110
526 IOL 0.9108
527 TH0 0.9105
528 1SQ 0.9103
529 R8S 0.9102
530 PBA 0.9100
531 GRE 0.9100
532 2LP 0.9098
533 3MB 0.9098
534 0BP 0.9097
535 9FL 0.9097
536 6M1 0.9096
537 9CA 0.9093
538 52C 0.9093
539 DHI 0.9090
540 RM1 0.9090
541 3BU 0.9089
542 OXQ 0.9089
543 45L 0.9088
544 ASN 0.9087
545 5SG 0.9084
546 12T 0.9083
547 MET 0.9083
548 M6W 0.9083
549 LYL 0.9083
550 HHI 0.9083
551 M45 0.9082
552 9RW 0.9081
553 VNL 0.9081
554 3SL 0.9080
555 5IQ 0.9078
556 HSE 0.9077
557 ORN 0.9077
558 1LQ 0.9075
559 152 0.9074
560 4XV 0.9074
561 NK 0.9074
562 OVM 0.9074
563 0JD 0.9074
564 HSO 0.9071
565 O72 0.9070
566 SD4 0.9070
567 HPS 0.9068
568 GVG 0.9068
569 PO6 0.9068
570 7VP 0.9067
571 I3A 0.9067
572 FA1 0.9067
573 0FN 0.9066
574 HX2 0.9066
575 PRS 0.9065
576 24W 0.9064
577 0V5 0.9063
578 PEQ 0.9063
579 5AC 0.9063
580 FDB 0.9063
581 JZ3 0.9061
582 258 0.9061
583 261 0.9059
584 F31 0.9059
585 FPY 0.9058
586 HCS 0.9057
587 2D0 0.9056
588 URP 0.9054
589 ES1 0.9053
590 0P6 0.9052
591 NLE 0.9051
592 URO 0.9051
593 IWT 0.9051
594 1NP 0.9051
595 B24 0.9050
596 2F6 0.9049
597 5Q0 0.9049
598 TAG 0.9048
599 4YS 0.9048
600 0R0 0.9047
601 1P7 0.9046
602 ILE 0.9043
603 4HM 0.9043
604 1DU 0.9042
605 HQY 0.9041
606 KUF 0.9040
607 23A 0.9038
608 MCT 0.9038
609 Q88 0.9038
610 15N 0.9036
611 5XB 0.9035
612 1P3 0.9034
613 9X7 0.9034
614 CWS 0.9034
615 HQJ 0.9034
616 JAB 0.9033
617 36E 0.9033
618 XLS 0.9030
619 BEA 0.9030
620 9R5 0.9030
621 7HQ 0.9029
622 JPZ 0.9029
623 N5J 0.9029
624 1MC 0.9029
625 42J 0.9028
626 LPK 0.9028
627 R9Y 0.9025
628 8CM 0.9025
629 SIN 0.9024
630 YPN 0.9022
631 GCU 0.9022
632 FBW 0.9022
633 4XS 0.9020
634 82I 0.9020
635 QIC 0.9020
636 M1Q 0.9020
637 5RN 0.9018
638 ES0 0.9016
639 G3F 0.9015
640 PYJ 0.9014
641 5RG 0.9013
642 5MH 0.9011
643 JFJ 0.9011
644 271 0.9010
645 LEU 0.9009
646 GZ3 0.9008
647 3HG 0.9008
648 DHS 0.9007
649 6F0 0.9007
650 Q24 0.9006
651 J9W 0.9006
652 R67 0.9005
653 APY 0.9005
654 TDR 0.9004
655 92K 0.9004
656 AZF 0.9003
657 URF 0.9003
658 4CL 0.9002
659 9ON 0.9002
660 MEV 0.9002
661 SOE 0.9001
662 BNL 0.9000
663 5WZ 0.9000
664 SME 0.9000
665 4HO 0.8999
666 HH8 0.8999
667 L5V 0.8999
668 CWM 0.8998
669 TAR 0.8997
670 ICF 0.8995
671 5B1 0.8995
672 A09 0.8992
673 FUM 0.8991
674 HH5 0.8991
675 SPV 0.8989
676 MZG 0.8988
677 3S5 0.8988
678 HSM 0.8988
679 DAL DAL 0.8986
680 ALA ALA 0.8986
681 2AC 0.8985
682 B85 0.8985
683 BPW 0.8984
684 ADE 0.8983
685 UFV 0.8980
686 S7J 0.8980
687 WOT 0.8980
688 JZ2 0.8979
689 PH3 0.8979
690 WBU 0.8979
691 R8A 0.8979
692 PJW 0.8979
693 KMH 0.8978
694 SVD 0.8978
695 4JJ 0.8977
696 EUG 0.8976
697 XXG 0.8975
698 M2K 0.8973
699 BTY 0.8972
700 PYD 0.8971
701 ICP 0.8971
702 449 0.8971
703 B53 0.8971
704 6GU 0.8971
705 XBZ 0.8970
706 34A 0.8969
707 K97 0.8969
708 OHP 0.8969
709 4ZE 0.8968
710 ICO 0.8967
711 E1T 0.8967
712 13P 0.8966
713 HY3 0.8966
714 SWD 0.8966
715 51R 0.8965
716 M5K 0.8965
717 AJ2 0.8965
718 SWA 0.8964
719 2QC 0.8963
720 5JC 0.8963
721 ORO 0.8963
722 XYD 0.8962
723 9YL 0.8962
724 1CO 0.8960
725 4XH 0.8960
726 GTQ 0.8960
727 B40 0.8959
728 L3Q 0.8959
729 R9S 0.8957
730 HX4 0.8956
731 MWM 0.8956
732 CEE 0.8956
733 9DG 0.8956
734 A1U 0.8955
735 XAN 0.8955
736 97T 0.8955
737 5RO 0.8954
738 RSF 0.8954
739 GWM 0.8953
740 2MP 0.8953
741 K5W 0.8953
742 AZ9 0.8953
743 BR9 0.8951
744 15L 0.8951
745 9ZE 0.8950
746 JBK 0.8950
747 XAZ 0.8949
748 286 0.8949
749 J1Z 0.8949
750 27Y 0.8948
751 TWO 0.8948
752 HQD 0.8948
753 YH7 0.8947
754 CH9 0.8947
755 6KT 0.8947
756 KTJ 0.8946
757 5UC 0.8944
758 4HC 0.8944
759 2ZV 0.8942
760 EN1 0.8941
761 39O 0.8940
762 3AE 0.8939
763 AQO 0.8939
764 URC 0.8939
765 PHE 0.8938
766 7B4 0.8938
767 MAJ 0.8937
768 1LN 0.8937
769 2YU 0.8937
770 IP0 0.8936
771 10L 0.8936
772 K7M 0.8935
773 FBF 0.8934
774 2AL 0.8934
775 KT7 0.8933
776 AES 0.8933
777 MNM 0.8932
778 42A 0.8932
779 UNJ 0.8932
780 JBH 0.8931
781 TYE 0.8931
782 2HC 0.8930
783 0N7 0.8929
784 GAF 0.8928
785 54G 0.8928
786 JZ4 0.8928
787 3IT 0.8927
788 KJY 0.8925
789 MEW 0.8925
790 F1A 0.8925
791 AZ8 0.8925
792 RUY 0.8924
793 GLA 0.8924
794 9TZ 0.8923
795 XCZ 0.8922
796 PRY 0.8921
797 DFB 0.8921
798 1A7 0.8918
799 PE0 0.8918
800 AZA 0.8918
801 TZE 0.8917
802 ADZ 0.8917
803 TFB 0.8917
804 5M0 0.8916
805 275 0.8916
806 KP6 0.8916
807 3XX 0.8916
808 BNF 0.8915
809 AW5 0.8915
810 MWJ 0.8915
811 QBK 0.8915
812 X6X 0.8914
813 MPV 0.8914
814 LR5 0.8912
815 4SD 0.8912
816 3PG 0.8912
817 MO8 0.8912
818 ESI 0.8912
819 LZM 0.8910
820 0CU 0.8910
821 PA1 0.8909
822 GIF 0.8909
823 DX4 0.8909
824 HNK 0.8908
825 6MP 0.8908
826 1LM 0.8908
827 A2F 0.8908
828 TEO 0.8906
829 H62 0.8906
830 428 0.8906
831 FK8 0.8905
832 0TR 0.8905
833 43M 0.8904
834 6AP 0.8904
835 2BX 0.8903
836 GOJ 0.8903
837 PRA 0.8903
838 1KP 0.8902
839 HPA 0.8902
840 D1X 0.8901
841 MAH 0.8900
842 1XM 0.8900
843 HT4 0.8899
844 2PG 0.8899
845 N8Y 0.8899
846 SX1 0.8898
847 1GN 0.8898
848 SOR 0.8898
849 HNL 0.8897
850 QOS 0.8897
851 TM7 0.8897
852 OXC 0.8897
853 Z5P 0.8896
854 B55 0.8896
855 GUN 0.8896
856 8S0 0.8895
857 0W8 0.8894
858 3FH 0.8894
859 R20 0.8893
860 XDE 0.8893
861 OW4 0.8893
862 B62 0.8892
863 GLY GLY 0.8891
864 YIO 0.8891
865 5MK 0.8891
866 F81 0.8890
867 75K 0.8890
868 2CQ 0.8890
869 DAS 0.8889
870 LGC 0.8889
871 QWW 0.8889
872 6CS 0.8889
873 5JQ 0.8888
874 N4B 0.8887
875 F4K 0.8887
876 2FG 0.8885
877 9FE 0.8885
878 JZ1 0.8885
879 GCS 0.8884
880 IGA 0.8884
881 34D 0.8883
882 2EC 0.8883
883 6TZ 0.8882
884 3Z8 0.8881
885 141 0.8881
886 DHY 0.8878
887 IUR 0.8877
888 8WT 0.8875
889 BCP 0.8875
890 F0J 0.8874
891 PPY 0.8874
892 9DA 0.8874
893 CFP 0.8871
894 ALL 0.8871
895 DTU 0.8870
896 DOR 0.8869
897 GXY 0.8869
898 GXL 0.8868
899 CTS 0.8867
900 GCB 0.8865
901 92P 0.8865
902 AN3 0.8864
903 44W 0.8863
904 I4B 0.8862
905 EQT 0.8860
906 4P0 0.8859
907 GLO 0.8859
908 PGH 0.8857
909 GLL 0.8856
910 BP1 0.8856
911 149 0.8856
912 T2C 0.8856
913 1Z6 0.8855
914 AJV 0.8855
915 4TU 0.8854
916 N3W 0.8854
917 1WG 0.8854
918 GP9 0.8851
919 SLS 0.8851
920 CRN 0.8851
921 Q02 0.8850
922 8TX 0.8850
923 KYD 0.8850
924 M6N 0.8848
925 FUL 0.8848
926 V55 0.8848
927 DVQ 0.8846
928 WOO 0.8845
929 2H5 0.8845
930 OTW 0.8845
931 XIZ 0.8845
932