-->
Receptor
PDB id Resolution Class Description Source Keywords
2B8W 2.22 Å EC: 3.-.-.- CRYSTAL-STRUCTURE OF THE N-TERMINAL LARGE GTPASE DOMAIN OF H GUANYLATE BINDING PROTEIN 1 (HGBP1) IN COMPLEX WITH GMP/ALF HOMO SAPIENS PROTEIN- GUANINE NUCLEOTIDE COMPLEX SIGNALING PROTEIN
Ref.: HOW GUANYLATE-BINDING PROTEINS ACHIEVE ASSEMBLY-STI PROCESSIVE CLEAVAGE OF GTP TO GMP. NATURE V. 440 101 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ALF 5GP A:594;
B:594;
Valid;
Valid;
none;
none;
submit data
464.181 n/a P(=O)...
MG A:595;
B:595;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2B8W 2.22 Å EC: 3.-.-.- CRYSTAL-STRUCTURE OF THE N-TERMINAL LARGE GTPASE DOMAIN OF H GUANYLATE BINDING PROTEIN 1 (HGBP1) IN COMPLEX WITH GMP/ALF HOMO SAPIENS PROTEIN- GUANINE NUCLEOTIDE COMPLEX SIGNALING PROTEIN
Ref.: HOW GUANYLATE-BINDING PROTEINS ACHIEVE ASSEMBLY-STI PROCESSIVE CLEAVAGE OF GTP TO GMP. NATURE V. 440 101 2006
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 253 families.
1 2B8W - ALF 5GP n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 2B8W - ALF 5GP n/a n/a
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 174 families.
1 1F5N - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 2B8W - ALF 5GP n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ALF 5GP; Similar ligands found: 107
No: Ligand ECFP6 Tc MDL keys Tc
1 ALF 5GP 1 1
2 ALF GDP 0.857143 1
3 GDP ALF 0.857143 1
4 GDP AF3 0.772727 1
5 G 0.753086 0.9
6 5GP 0.753086 0.9
7 GDP 0.729412 0.888889
8 GP3 0.717647 0.86747
9 GP2 0.709302 0.857143
10 GNH 0.701149 0.878049
11 GCP 0.696629 0.86747
12 G2P 0.688889 0.857143
13 GTP 0.685393 0.888889
14 GMV 0.685393 0.890244
15 G G 0.680412 0.890244
16 G1R 0.677778 0.878049
17 GSP 0.67033 0.847059
18 GNP 0.67033 0.86747
19 9GM 0.67033 0.86747
20 GDP 7MG 0.666667 0.879518
21 GAV 0.655914 0.857143
22 GMP 0.6375 0.802469
23 G2R 0.635417 0.857143
24 GPG 0.628866 0.857143
25 YGP 0.61 0.827586
26 A G 0.609091 0.901235
27 6CK 0.607843 0.903614
28 G3A 0.607843 0.86747
29 Y9Z 0.60396 0.808989
30 GDC 0.60396 0.857143
31 GDD 0.60396 0.857143
32 GKE 0.60396 0.857143
33 U A G G 0.603604 0.901235
34 G5P 0.601942 0.86747
35 GFB 0.598039 0.857143
36 GTG 0.598039 0.858824
37 GDR 0.598039 0.857143
38 G A A A 0.594595 0.890244
39 GKD 0.580952 0.857143
40 JB2 0.580952 0.857143
41 GPD 0.575472 0.827586
42 GDX 0.575472 0.86747
43 GCP G 0.574257 0.8875
44 3GP 0.573034 0.864198
45 G3D 0.56701 0.876543
46 G4P 0.555556 0.876543
47 G1R G1R 0.554622 0.869048
48 PGD O 0.55 0.784946
49 JB3 0.54955 0.847059
50 NGD 0.544643 0.879518
51 FEG 0.544643 0.808989
52 U2G 0.544643 0.837209
53 ZGP 0.539823 0.8
54 G U 0.539823 0.869048
55 CG2 0.535088 0.837209
56 0O2 0.533981 0.876543
57 2MD 0.530435 0.8
58 G C 0.530435 0.869048
59 CAG 0.529915 0.811111
60 2GP 0.521739 0.853659
61 MGD 0.516949 0.8
62 FE9 0.516667 0.755102
63 MD1 0.512397 0.8
64 DBG 0.504065 0.847059
65 PGD 0.5 0.827586
66 TPG 0.491935 0.757895
67 G G G C 0.491803 0.858824
68 G G G RPC 0.491525 0.845238
69 GPX 0.490385 0.841463
70 A G C C 0.487805 0.879518
71 APC G U 0.487603 0.855422
72 DGI 0.484848 0.823529
73 DGP 0.484211 0.833333
74 DG 0.484211 0.833333
75 P2G 0.479167 0.807229
76 DG DG 0.476636 0.837209
77 ALF ADP 0.475248 0.9125
78 ADP ALF 0.475248 0.9125
79 G C C C 0.472441 0.869048
80 GH3 0.471154 0.865854
81 P1G 0.469388 0.797619
82 G4M 0.466165 0.791209
83 BGO 0.466102 0.825581
84 AKW 0.466102 0.818182
85 DGT 0.466019 0.823529
86 A G U 0.462687 0.858824
87 IMP 0.458333 0.875
88 IDP 0.45 0.864198
89 A G U U 0.446043 0.858824
90 GGM 0.442623 0.806818
91 5GP 5GP 0.441176 0.851852
92 G7M 0.438776 0.890244
93 G U34 0.438017 0.858824
94 SGP 0.434343 0.758621
95 GPC 0.432 0.872093
96 35G 0.431373 0.851852
97 PCG 0.431373 0.851852
98 C2E 0.431373 0.841463
99 G1G 0.425197 0.848837
100 R5I 0.419048 0.841463
101 R7I 0.419048 0.841463
102 DC DG 0.408 0.818182
103 ADP PO3 0.407767 0.8375
104 MGP 0.40566 0.879518
105 3PD UM3 0.403226 0.816092
106 6G0 0.401869 0.879518
107 GAP 0.4 0.819277
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2B8W; Ligand: ALF 5GP; Similar sites found with APoc: 622
This union binding pocket(no: 1) in the query (biounit: 2b8w.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 1EK0 GNP None
2 6F7X MFU None
3 3TK1 GDP 1.21951
4 3BFX A3P 1.35135
5 3BFV ADP 1.47601
6 4BAS GNP 1.50754
7 6AU6 GDP 1.52439
8 1SVK ALF GDP 1.52439
9 4XGU ADP 1.52439
10 1Y3A GDP 1.52439
11 4NE2 SH2 1.52439
12 4NE2 ADP 1.52439
13 2OM2 GDP 1.53846
14 1BH2 GSP 1.5873
15 1SQ5 ADP 1.62338
16 1P4V GLY 1.69492
17 1G3M A3P 1.70068
18 1G3M PCQ 1.70068
19 2DPY ADP 1.82927
20 5H7K GDP 1.82927
21 2C9O ADP 1.82927
22 5M7P ADP 1.82927
23 4CSD MFU 1.83824
24 2ZPT A3P 2.0339
25 4D81 ADP 2.12014
26 4FRZ ADP 2.13415
27 3LRE ADP 2.13415
28 4J0Q GDP 2.13415
29 3DZD ADP 2.13415
30 5EE7 5MV 2.13415
31 5KDO GDP 2.13415
32 1SVM ATP 2.13415
33 5M04 GDP 2.13415
34 2J0W ASP 2.13415
35 5WRI A3P 2.1875
36 4WOP CTP 2.22222
37 3E5H GNP 2.24719
38 5DT6 GLU 2.24719
39 2VWT PYR 2.24719
40 3NHB ADP 2.28758
41 5L3W GDP 2.28758
42 5WRJ A3P 2.31023
43 5X40 ACP 2.39726
44 3COB ADP 2.43902
45 5ZXD ATP 2.43902
46 5WC2 ADP 2.43902
47 4HSE ADP 2.43902
48 5Y6N ADP 2.43902
49 1LVK MNT BEF 2.43902
50 3RC3 ANP 2.43902
51 1W5T ANP 2.43902
52 1W5T ADP 2.43902
53 5GOE GDP 2.43902
54 2Q2Y MKR 2.43902
55 2Q2Y ADP 2.43902
56 1R0X ATP 2.44755
57 3BOS CDP 2.47934
58 3CT5 NAG NAG NAG 2.51572
59 1W4R TTP 2.5641
60 5NM7 GLY 2.63158
61 5UIV ADP 2.64317
62 5G3Y ADP 2.65487
63 3GD8 GOL 2.69058
64 4F2Q QUS 2.71318
65 2ZFI ADP 2.73224
66 4PPF FLC 2.7439
67 1WDT GTP 2.7439
68 3WYA GDP 2.7439
69 1DAR GDP 2.7439
70 1G7S GDP 2.7439
71 2FAH GDP 2.7439
72 2O0J ADP 2.7439
73 2FSH ANP 2.7439
74 5I34 GDP 2.7439
75 4PFO ADP 2.7439
76 6FAA ADP 2.7439
77 5EXT ADP 2.7439
78 2ZTS ADP 2.7439
79 5Z0A NAG 2.7439
80 4B2D FBP 2.7439
81 1ZIN AP5 2.76498
82 2ZE7 DST 2.7668
83 2ZE7 AMP 2.7668
84 1FP6 ADP 2.76817
85 4TTQ ATP 2.7907
86 1NJF ADP 2.8
87 1NJF AGS 2.8
88 4X8O AP5 2.80374
89 1VKJ A3P 2.80702
90 5J1J ANP 2.80702
91 3MGB PAP 2.82132
92 2ODE ALF GDP 2.83688
93 6G47 SIA SIA 2.87081
94 4LPS GDP 2.89256
95 1JJV ATP 2.91262
96 4E03 ADP 2.91262
97 1Z08 GNP 2.94118
98 5DHF GNP 2.95359
99 5DIF GNP 2.95359
100 5UWH GNP 2.95359
101 6CIT GNP 2.95359
102 5UWT GNP 2.95359
103 5UWP GNP 2.95359
104 5UWU GNP 2.95359
105 5UWW GNP 2.95359
106 5UWS GNP 2.95359
107 5UWQ GNP 2.95359
108 5UWO GNP 2.95359
109 5UWI GNP 2.95359
110 5UWR GNP 2.95359
111 5UWJ GNP 2.95359
112 5DI9 GNP 2.95359
113 4DDY DN6 3.04183
114 3CX8 GSP 3.04878
115 1OXV ANP 3.04878
116 5BQ5 ADP BEF 3.04878
117 3FKQ ATP 3.04878
118 1XKV ATP 3.04878
119 5XDR ADP 3.04878
120 5H7J GCP 3.04878
121 2XAU ADP 3.04878
122 3EZ2 ADP 3.04878
123 3IO3 ADP 3.04878
124 2YOH WMJ 3.04878
125 4YS0 ADP 3.04878
126 2IS6 ADP 3.04878
127 4V03 ADP 3.11284
128 2ZPA ADP 3.12966
129 4BFW ZVW 3.14465
130 4HAT GNP 3.24074
131 4DKX GDP 3.24074
132 3FB4 AP5 3.24074
133 4WEI GLC GAL 3.2491
134 2EFE GNH 3.31492
135 2AWN ADP 3.35366
136 5TSH ADP 3.35366
137 6A20 ADP 3.35366
138 2BVN GNP 3.35366
139 5TSH ANP 3.35366
140 3U6B GDP 3.35366
141 4IHQ ADP 3.35366
142 5W76 GDP 3.35366
143 1D8T GDP 3.35366
144 4G5G GDP 3.35366
145 3U6K GDP 3.35366
146 5W75 GDP 3.35366
147 5ZBR ANP 3.35366
148 6B4K ANP 3.35366
149 1NY5 ADP 3.35366
150 4PC3 GDP 3.35366
151 3QKT ANP 3.35366
152 1P9B GDP 3.35366
153 2CJP VPR 3.35366
154 1NHX FTB 3.35366
155 1NHX PEP 3.35366
156 5JBQ GDP 3.35366
157 5IFS ADP 3.37553
158 1G41 ADP 3.37838
159 1NST A3P 3.38462
160 3TBK ANP 3.42342
161 1KO8 6PG 3.42857
162 1YRB GDP 3.43511
163 2QZ4 ADP 3.43511
164 4WZ6 ATP 3.44828
165 2CDN ADP 3.48259
166 5K5Z ANP 3.50318
167 4YDS ATP 3.50877
168 5E5U MLI 3.51759
169 5H4S RAM 3.52113
170 3T1O GDP 3.53535
171 1CS4 GSP 3.55556
172 6C74 PC 3.6036
173 3QH2 3NM 3.61991
174 1AKY AP5 3.63636
175 4ZNL BEF ADP 3.64964
176 2C77 GNP 3.65854
177 2C78 GNP 3.65854
178 2XTZ GSP 3.65854
179 1KK1 GNP 3.65854
180 1Z6T ADP 3.65854
181 4OHY ANP 3.65854
182 2HS3 FGR 3.65854
183 5KSZ GCP 3.65854
184 1YAA MAE 3.65854
185 4ZDJ UTP 3.74787
186 4A9C B5F 3.79747
187 2PL3 ADP 3.81356
188 2VOH CIT 3.82166
189 1L2T ATP 3.82979
190 2GK6 ADP 3.84615
191 6CRK GDP 3.861
192 2BCG GDP 3.8835
193 2RGX AP5 3.8835
194 2Y8E GNP 3.91061
195 2NV2 GLN 3.92157
196 1RYH GNP 3.94089
197 3IUY AMP 3.94737
198 4NCN GTP 3.96341
199 4TMZ GSP 3.96341
200 1F9V ADP 3.96341
201 5GVR LMR 3.96341
202 2CK3 ANP 3.96341
203 1W0J ADP 3.96341
204 2BIF ANP 3.96341
205 2BIF SIN 3.96341
206 1K6M AGS 3.96341
207 2CE7 ADP 3.96341
208 5LTJ ADP 3.96341
209 1W0J ADP BEF 3.96341
210 2CK3 ADP 3.96341
211 5LTJ BEF 3.96341
212 1QF5 GDP 3.96341
213 1QF5 RPL 3.96341
214 2J5V PCA 3.96341
215 2JGV ADP 3.96341
216 4QDI ATP 3.96341
217 1RRC ADP 3.98671
218 2OZE AGS 4.02685
219 2GWH A3P 4.02685
220 2FFQ GSP 4.09357
221 1YZQ GNP 4.11765
222 4NU0 AP5 4.14747
223 2OG2 MLI 4.17827
224 1XX6 ADP 4.18848
225 5HCN GCP 4.21456
226 2X7I CIT 4.22078
227 2NCD ADP 4.26829
228 2QN6 GDP 4.26829
229 4RD0 GDP 4.26829
230 3T34 GDP 4.26829
231 4P4T GDP 4.26829
232 2GKS ADP 4.26829
233 1MKY GDP 4.26829
234 1BG2 ADP 4.30769
235 1D5C GDP 4.32099
236 4GBM A3P 4.33437
237 1GXU 2HP 4.3956
238 4P3Y GDP 4.3956
239 3W5J GDP 4.41176
240 3FWY ADP 4.4586
241 4GOX A3P 4.47284
242 5G41 AP5 4.4843
243 5ZB0 ADP 4.54545
244 5ZB0 TYD 4.54545
245 1T5C ADP 4.57317
246 5I0H ADP BEF 4.57317
247 2ZR9 DTP 4.57317
248 2RCN GDP 4.57317
249 2OBM ADP 4.57317
250 5AK0 8V1 4.57317
251 4Y4V DAL 4.57317
252 1IN4 ADP 4.57317
253 1P72 ADP 4.57317
254 1Z83 AP5 4.59184
255 3TMK T5A 4.62963
256 3DC4 ADP 4.65116
257 6AIC AMP 4.6729
258 2ORV 4TA 4.70085
259 1U8Z GDP 4.7619
260 1T8U A3P 4.77941
261 1T8U UAP SGN IDS SGN 4.77941
262 2OFW ADX 4.80769
263 3Q72 GNP 4.81928
264 3BER AMP 4.81928
265 1U0J ADP 4.86891
266 5IRR GSP 4.87013
267 5W7Q GDP 4.87805
268 5HR5 ADP 4.87805
269 2FNA ADP 4.87805
270 4YJ1 ADP 4.87805
271 4H1V GNP 4.87805
272 1IWE IMP 4.87805
273 5SZH GNP 4.92611
274 2A9K GDP 4.93274
275 5MVR ADP 4.93827
276 3ZQ6 ADP ALF 4.93827
277 2XZ9 PYR 4.93827
278 2XT3 ADP 4.94186
279 3B9Q MLI 4.96689
280 2EW1 GNP 4.97512
281 1UAD GNP 5.05051
282 6BSX GDP 5.05618
283 6BSX E7S 5.05618
284 1G6H ADP 5.05837
285 3RLF ANP 5.06757
286 1S3G AP5 5.06912
287 3QVV A3P 5.08475
288 3QVV 3QV 5.08475
289 3TKL GTP 5.10204
290 4HI0 GDP 5.11811
291 1B7T ADP 5.12821
292 4PX9 ADP 5.13699
293 2FH5 GTP 5.14019
294 1D2N ANP 5.14706
295 1OFH ADP 5.17241
296 3ZFD ANP 5.18293
297 1M2O GNP 5.18293
298 5YT0 GDP 5.18293
299 4DCT GDP 5.18293
300 5FG3 GDP 5.18293
301 4WZA ACP 5.18293
302 4WZA ADP 5.18293
303 1D2E GDP 5.18293
304 3P4X ADP 5.18293
305 5IRN ADP 5.18293
306 1YTM ATP 5.18293
307 1X8J A3P 5.18293
308 1KK8 BEF ADP 5.19481
309 2PZE ATP 5.24017
310 3AB3 GDP 5.24862
311 1ZCB GDP 5.24862
312 1Z06 GNP 5.29101
313 5OCG GNP 5.29101
314 5UQW GDP 5.29101
315 1G16 GDP 5.29412
316 2HF9 GSP 5.30973
317 1YVD GNP 5.32544
318 3Q85 GNP 5.32544
319 2Z5F A3P 5.36913
320 1YZN GNP 5.40541
321 1JI0 ATP 5.41667
322 5OEC GDP 5.46448
323 2CBZ ATP 5.48523
324 1GOJ ADP 5.4878
325 2WHX ADP 5.4878
326 5FTB ANP 5.4878
327 4LYA ATP 5.4878
328 5FHD ADP ALF 5.4878
329 3FVQ ATP 5.4878
330 2JLR ANP 5.4878
331 3SFV GDP 5.52486
332 2PEZ DAT 5.58659
333 5L3R GCP 5.64784
334 1QF9 ADP 5.6701
335 1QF9 ALF 5.6701
336 1QF9 C5P 5.6701
337 3NKV GNP 5.71429
338 3DKP ADP 5.71429
339 2CJW GDP 5.72917
340 3QBT GNP 5.74713
341 3TNF GNP 5.74713
342 4LHW GNP 5.74713
343 2A5J GDP 5.75916
344 1JJ7 ADP 5.76923
345 4NON GDP 5.76923
346 2C5L GTP 5.78035
347 2VVG ADP 5.79268
348 1SKQ GDP 5.79268
349 2WKQ GTP 5.79268
350 4ZG4 VO4 ADP 5.79268
351 1FNN ADP 5.79268
352 1AQU A3P 5.79268
353 4K81 GTP 5.84795
354 1GWN GTP 5.85366
355 4Z7X 3CX 5.88235
356 5O2T GSP 5.91716
357 3RWO GDP 5.94595
358 4KVG GTP 5.95238
359 1VHT BA3 5.9633
360 3X1Z GNP 5.98802
361 3UIE ANP 6
362 3DDC GNP 6.0241
363 1CLU DBG 6.0241
364 3KUD GDP 6.0241
365 3KTA AP5 6.04396
366 3WXM GTP 6.09756
367 3VMF GTP 6.09756
368 5MZN ADP 6.09756
369 1IHU AF3 6.09756
370 1IHU ADP 6.09756
371 5JCZ GDP 6.14525
372 3Q9L ATP 6.15385
373 1X1R GDP 6.17978
374 1ZC3 GNP 6.19469
375 5KSP GDP 6.31579
376 4JLV ADP 6.3197
377 2HT6 GDP 6.32184
378 1Z0A GDP 6.32184
379 5CK5 GDP 6.32911
380 1HTW ADP 6.32911
381 4IEE AGS 6.40244
382 5LB3 ADP 6.40244
383 1OYY AGS 6.40244
384 4PJ3 ANP 6.40244
385 1E2K TMC 6.40244
386 1ZJ6 G3D 6.41711
387 4QM7 GTP 6.43275
388 4RZ3 ADP 6.44068
389 5DI3 GNP 6.48649
390 1B0U ATP 6.48855
391 1M7B GTP 6.52174
392 3AQ4 GDP 6.52174
393 3GJ8 GDP 6.52174
394 3FYH ADP 6.52174
395 3A4M ADP 6.53846
396 5LWY OLB 6.54206
397 4U00 ADP 6.55738
398 1F6B GDP 6.56566
399 1RJ9 GCP 6.57895
400 5TDC NMM ILE PHE SER 6.57895
401 1ION ADP 6.58436
402 2QTV GNP 6.58683
403 1KAO GDP 6.58683
404 1MR3 G3D 6.62983
405 4R2I ANP 6.66667
406 5L3V GDP 6.68896
407 1Z0F GDP 6.70391
408 3A1S GDP 6.70732
409 5BN3 ADP 6.70732
410 4LJ9 ACP 6.70732
411 5L3S GNP 6.71141
412 5U32 GDP 6.77966
413 1S8F GDP 6.77966
414 3PCR GTP 6.79012
415 1APZ ASP 6.79012
416 4QOS ADP 6.79245
417 4BQS ADP 6.81818
418 5KUT GDP 6.87831
419 1NRJ GTP 6.88073
420 3BIB PSF 6.89655
421 2WJG GDP 6.91489
422 1ZD9 GDP 6.91489
423 4YLG GDP 6.93642
424 5BYK OAQ 6.94981
425 5BYK A3P 6.94981
426 3B7G ANP 6.95652
427 1NN5 2DT 6.97674
428 1NN5 ANP 6.97674
429 2BME GNP 6.98925
430 5JCP GDP ALF 7.0122
431 1DNP MHF 7.0122
432 4NZ6 DGL 7.0122
433 1UPT GTP 7.01754
434 2IYL GDP 7.04225
435 4M9Q GNP 7.04846
436 4FCW ADP 7.07396
437 2J0V GDP 7.07547
438 2CHG ANP 7.07965
439 1CR1 TTP 7.09459
440 4KAX GTP 7.10059
441 1ZUI SKM 7.14286
442 1Z2A GDP 7.14286
443 3CPJ GDP 7.17489
444 3PQC GDP 7.17949
445 2J59 GTP 7.22892
446 1O3Y GTP 7.22892
447 1J2J GTP 7.22892
448 3DEF GDP 7.25191
449 1R4A GNP 7.27273
450 1FQJ ALF 7.31707
451 1V8K ANP 7.31707
452 4B47 GDP 7.31707
453 4R43 GDP 7.31707
454 1FQJ GDP 7.31707
455 5Z69 AGS 7.31707
456 4MKF AP5 7.31707
457 4MKG AP5 7.31707
458 3NIM ARG ARG ALA ALA 7.31707
459 1S9D GDP 7.31707
460 4CVN ADP 7.32984
461 3N5C GDP 7.40741
462 1F2U ATP 7.43243
463 5H67 ATP 7.44681
464 4TL6 ANP 7.50988
465 2F9L GDP 7.53769
466 5LEF GTP 7.57576
467 1TU3 GNP 7.60234
468 4ZKD GDP 7.62195
469 1R2Q GNP 7.64706
470 4R98 GNH 7.74908
471 5O74 GDP 7.77778
472 2W83 GTP 7.79221
473 3AI8 HNQ 7.8125
474 3B5J 12D 7.81893
475 2WJH FLC 7.83133
476 2WJH GDP 7.83133
477 1OIX GDP 7.8534
478 1OIV GDP 7.8534
479 4U5X GNP 7.86517
480 4JLS 3ZE 7.89474
481 4YMU ATP 7.91667
482 2Y65 ADP 7.92683
483 4A4Z ANP 7.92683
484 5H68 AGS 7.92683
485 3CV2 OXL 7.92683
486 3R7F CP 7.92683
487 5XKT GNP 8
488 1DAK ADP 8.03571
489 1DAK DPU 8.03571
490 2QG6 NMN 8.0402
491 1VG1 GDP 8.10811
492 2QQ0 ANP 8.15217
493 2QQ0 ADP 8.15217
494 2QQ0 TMP 8.15217
495 2QQ0 THM 8.15217
496 5WDR GNP 8.18713
497 3M1I GTP 8.21918
498 4KVA GTP 8.23171
499 3IIJ ADP 8.33333
500 3WYF GTP 8.40336
501 4LX0 BEF GDP 8.47458
502 5Z2M GTP 8.52273
503 3ZS9 ADP ALF 8.53659
504 2WOJ ADP ALF 8.53659
505 4XVU ATP 8.53659
506 1GUA GNP 8.64198
507 4C4P GNP 8.67052
508 1VG8 GNP 8.69565
509 1WA5 GTP 9.09091
510 5TIV A3P 9.09091
511 3WYG GTP 9.21053
512 2WIC GNP 9.3633
513 1VG9 GDP 9.45122
514 6C90 ADP 9.45122
515 1VG0 GDP 9.45122
516 1RE0 GDP 9.50226
517 4OI4 ATP 9.56522
518 1LVG ADP 9.59596
519 2BEK ATP 9.72763
520 1Y63 ADP 9.78261
521 4DID GDP 9.84456
522 1KY3 GDP 9.89011
523 1DS6 GDP 9.89583
524 4ITR GDP 9.94764
525 2WMO GTP 10
526 4HDO GNP 10.061
527 2W2X GSP 10.2703
528 2A5F GTP 10.2857
529 3T12 GDP ALF 10.2941
530 3E70 GDP 10.3659
531 1TQ4 GDP 10.3659
532 1H65 GDP 10.3704
533 1E96 GTP 10.4167
534 1I4D GDP 10.4167
535 4YC7 GNP 10.4972
536 5EE5 GTP 10.5263
537 3KJI ADP 10.6299
538 1G7C 5GP 10.6383
539 3SBD GNP 10.6952
540 1MH1 GNP 10.7527
541 1G4U AF3 10.8696
542 1G4U GDP 10.8696
543 1G3Q ADP 10.9705
544 4YDU ADP 10.9705
545 5UPK GNP 10.9756
546 3BD9 A3P 11.0714
547 3H4S ADP 11.1111
548 1YZG GDP 11.1732
549 2FJU GSP 11.236
550 5VHC BEF ADP 11.2805
551 5E95 GDP 11.3402
552 1PUJ GNP 11.3475
553 1M7G AV2 11.3744
554 1M7G ADP 11.3744
555 1M7G ADX 11.3744
556 5MEX PAP 11.5854
557 5MEX SZZ 11.5854
558 2GCO GNP 11.9403
559 2GCN GDP 11.9403
560 3GFS FMN 12.069
561 3DOE GTP 12.1212
562 2W58 ADP 12.3762
563 6BCB GSP 12.4324
564 6BCA GSP 12.4324
565 6BC0 GSP 12.4324
566 4D0N GDP 12.4324
567 5HPY GDP 12.4324
568 2UZI GTP 12.5
569 3GJX GTP 12.5
570 3LXR GDP 12.5
571 1W7J ADP BEF 12.5828
572 1HE1 AF3 12.5926
573 1HE1 GDP 12.5926
574 2X77 GDP 12.6984
575 4XOI GTP 12.7778
576 4XSH GSP 12.8492
577 3GJ7 GDP 13.2653
578 3EWA ANP 13.354
579 3CNL GNP 13.3588
580 1XMV ADP 13.4146
581 3ITJ CIT 13.4146
582 4XTR ATP 13.5135
583 4XTR ADP 13.5135
584 4V0K GDP 13.6095
585 1KSH GDP 13.8158
586 3T5G GDP 13.8158
587 5TB5 GDP 14
588 5TAR GDP 14.1892
589 4D0G GTP 14.4928
590 3BC1 GNP 14.8718
591 2UV4 AMP 15.1316
592 1XP8 AGS 15.3005
593 5J1S ATP 15.4472
594 1BO4 COA 15.4762
595 2ZEJ GDP 16.3043
596 5N69 ADP 17.0854
597 4Q1A 2XZ 17.1429
598 4Q1A UDP 17.1429
599 3GJ5 GDP 17.6471
600 4ZI2 GNP 17.8947
601 4GOJ GNP 17.9894
602 1PTR PRB 18
603 1FZQ GDP 18.7845
604 1Z0K GTP 18.8406
605 2KIN ADP 19
606 2V7Q ATP 19.697
607 2V7Q ADP 19.697
608 2GOO NDG 20.1754
609 3GJ4 GDP 21.2121
610 2VB6 ADP BEF 23.4899
611 3CH5 GDP 25
612 4HDQ GNP 26.9231
613 1Z0J GTP 27.1186
614 3WY9 GDP 28.125
615 2HCJ GDP 29.7297
616 3ZIA ATP 30.1587
617 3ZIA ADP 30.1587
618 3MJH GTP 32.3529
619 4IDN GNP 33.2317
620 5VGR GDP 37.8049
621 3QF7 ANP 38
622 3GJ3 GDP 39.3939
Pocket No.: 2; Query (leader) PDB : 2B8W; Ligand: ALF 5GP; Similar sites found with APoc: 18
This union binding pocket(no: 2) in the query (biounit: 2b8w.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 4WXJ GLU 1.48699
2 2ZJ5 ADP 2.13415
3 2JFZ DGL 2.7451
4 2JFZ 003 2.7451
5 1B74 DGN 3.14961
6 4MRP GSH 3.65854
7 2UVO NAG 4.09357
8 3UG4 AHR 4.26829
9 6A56 LAT 4.26829
10 1Q20 A3P 4.34783
11 1Q20 PLO 4.34783
12 3OEN GLU 4.8951
13 43CA NPO 5.30973
14 6H5E ANP 6.09756
15 4HDK 13X 6.70732
16 1Q19 SSC 7.31707
17 3ZW0 FUC 8.04598
18 1VBO MAN MAN MAN 9.39597
APoc FAQ
Feedback