Receptor
PDB id Resolution Class Description Source Keywords
2AHG 1.9 Å EC: 3.2.1.- UNSATURATED GLUCURONYL HYDROLASE MUTANT D88N WITH DGLCA-GALN BACILLUS SP. ALPHA6/ALPHA6 BARREL GLYCOSIDE HYDROLASE FAMILY 88 COMPLEXUNSATURATED CHONDROITIN DISACCHARIDE HYDROLASE
Ref.: CRYSTAL STRUCTURE OF UNSATURATED GLUCURONYL HYDROLA COMPLEXED WITH SUBSTRATE: MOLECULAR INSIGHTS INTO I CATALYTIC REACTION MECHANISM J.BIOL.CHEM. V. 281 29807 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NGA GCD D:1;
C:1;
 Valid;
Valid;
 none;
none;
 submit data
n/a n/a
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2FV1 1.73 Å EC: 3.2.1.- UGL_D88N/DGLCA-GLCNAC BACILLUS SP. ALPHA6/ALPHA6-BARREL HYDROLASE
Ref.: SUBSTRATE RECOGNITION BY UNSATURATED GLUCURONYL HYD FROM BACILLUS SP. GL1 BIOCHEM.BIOPHYS.RES.COMMUN. V. 344 253 2006
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 17 families.
1 2FV0 - BGC RAM BGC GAD n/a n/a
2 2AHG - NGA GCD n/a n/a
3 2FV1 - NDG GAD n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 17 families.
1 2FV0 - BGC RAM BGC GAD n/a n/a
2 2AHG - NGA GCD n/a n/a
3 2FV1 - NDG GAD n/a n/a
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 10 families.
1 2FV0 - BGC RAM BGC GAD n/a n/a
2 2AHG - NGA GCD n/a n/a
3 2FV1 - NDG GAD n/a n/a
4 3ANK - NG6 GCD n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: NGA GCD; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Ligands (3D)
Ligand no: 1; Ligand: NGA GCD; Similar ligands found: 25
No: Ligand Similarity coefficient
1 NGA GCD 1.0000
2 NAG GCD 0.9776
3 NAG GC4 0.9522
4 NAG GAD 0.9479
5 NGA GAL 0.9412
6 NDG GAD 0.9346
7 A2G GAL 0.9316
8 NAG BDP 0.9250
9 NAG GAL 0.9206
10 MGC GAL 0.9125
11 NOK GAL 0.9097
12 LOG GAL 0.9024
13 ASG GCD 0.9004
14 NG6 GCD 0.8950
15 NDG GCD 0.8828
16 NDG GAL 0.8812
17 NOY BGC 0.8771
18 NGA NAG 0.8758
19 ASG GC4 0.8728
20 BGC Z9D 0.8726
21 NGK GCD 0.8706
22 BGC GAL 0.8686
23 GAL NGT 0.8645
24 BGC BGC 0.8641
25 NGT GAL 0.8562
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2FV1; Ligand: NDG GAD; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2fv1.bio2) has 15 residues
No: Leader PDB Ligand Sequence Similarity
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