Receptor
PDB id Resolution Class Description Source Keywords
2A8X 2.4 Å EC: 1.8.1.4 CRYSTAL STRUCTURE OF LIPOAMIDE DEHYDROGENASE FROM MYCOBACTERIUM TUBERCULOSIS MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE; PYRUVATE DEHYDROGENASE; ALPHA KETO ACID DEHYDROGENASE; MYCOBACTERIUM TUBERCULOSIS OXIDOREDUCTASE
Ref.: CRYSTAL STRUCTURE AND FUNCTIONAL ANALYSIS OF LIPOAMIDE DEHYDROGENASE FROM MYCOBACTERIUM TUBERCULOSIS J.BIOL.CHEM. V. 280 33977 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FAD A:480;
B:580;
Valid;
Valid;
none;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
MPD A:590;
Invalid;
none;
submit data
118.174 C6 H14 O2 C[C@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2A8X 2.4 Å EC: 1.8.1.4 CRYSTAL STRUCTURE OF LIPOAMIDE DEHYDROGENASE FROM MYCOBACTERIUM TUBERCULOSIS MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE; PYRUVATE DEHYDROGENASE; ALPHA KETO ACID DEHYDROGENASE; MYCOBACTERIUM TUBERCULOSIS OXIDOREDUCTASE
Ref.: CRYSTAL STRUCTURE AND FUNCTIONAL ANALYSIS OF LIPOAMIDE DEHYDROGENASE FROM MYCOBACTERIUM TUBERCULOSIS J.BIOL.CHEM. V. 280 33977 2005
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 10 families.
1 2A8X - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 2A8X - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2A8X - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 2F5Z - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FAD; Similar ligands found: 119
No: Ligand ECFP6 Tc MDL keys Tc
1 FAS 1 1
2 FAD 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 DAL FAD PER 0.772414 0.951807
7 FAE 0.751773 0.987654
8 SFD 0.651007 0.860215
9 FDA 0.641892 0.906977
10 FNK 0.602564 0.876405
11 62F 0.572327 0.939024
12 F2N 0.566265 0.886364
13 FMN 0.543307 0.876543
14 FA9 0.526316 0.939759
15 6YU 0.516304 0.860215
16 CNV FAD 0.511905 0.908046
17 P6G FDA 0.511628 0.908046
18 FAD NBT 0.508876 0.83871
19 A2D 0.504065 0.875
20 P5F 0.491329 0.941176
21 FAD CNX 0.488506 0.8125
22 APR 0.488372 0.851852
23 AR6 0.488372 0.851852
24 AGS 0.484615 0.811765
25 SAP 0.484615 0.811765
26 M33 0.484375 0.864198
27 BA3 0.484127 0.875
28 FAD NBA 0.480663 0.802083
29 ATP 0.48062 0.851852
30 B4P 0.480315 0.875
31 ADP 0.480315 0.851852
32 AP5 0.480315 0.875
33 ANP 0.477273 0.831325
34 AQP 0.476923 0.851852
35 5FA 0.476923 0.851852
36 48N 0.469388 0.902439
37 OAD 0.467626 0.876543
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AD9 0.462121 0.831325
41 3OD 0.460993 0.876543
42 RBF 0.460938 0.790123
43 FB0 0.460606 0.835165
44 139 0.460526 0.858824
45 AP0 0.46 0.835294
46 A22 0.459854 0.864198
47 ACP 0.458015 0.853659
48 8QN 0.456522 0.864198
49 PRX 0.454545 0.831325
50 A1R 0.453237 0.86747
51 G3A 0.452055 0.902439
52 T5A 0.45098 0.872093
53 G5P 0.44898 0.902439
54 ATF 0.448529 0.821429
55 50T 0.44697 0.819277
56 ACQ 0.444444 0.853659
57 PAJ 0.442857 0.847059
58 ADQ 0.442857 0.853659
59 5AL 0.441176 0.864198
60 ADX 0.439394 0.775281
61 CA0 0.439394 0.853659
62 A4P 0.437909 0.831461
63 25L 0.4375 0.864198
64 P33 FDA 0.436464 0.817204
65 5SV 0.435714 0.793103
66 TXE 0.434211 0.890244
67 OMR 0.434211 0.818182
68 ABM 0.434109 0.829268
69 A 0.433071 0.82716
70 AMP 0.433071 0.82716
71 4AD 0.432624 0.855422
72 ADJ 0.432258 0.818182
73 BIS 0.430556 0.802326
74 SRA 0.429688 0.788235
75 AFH 0.42953 0.825581
76 TXD 0.427632 0.890244
77 NXX 0.427632 0.865854
78 UP5 0.427632 0.878049
79 DND 0.427632 0.865854
80 6V0 0.427632 0.857143
81 SRP 0.42446 0.843373
82 PR8 0.423611 0.837209
83 TAT 0.423358 0.821429
84 AMO 0.422535 0.865854
85 PTJ 0.42069 0.835294
86 FYA 0.42069 0.864198
87 TXA 0.42069 0.865854
88 CNA 0.420382 0.865854
89 00A 0.41958 0.823529
90 AHX 0.41958 0.835294
91 MAP 0.41844 0.811765
92 NAI 0.418301 0.845238
93 AU1 0.41791 0.831325
94 AP2 0.416667 0.843373
95 A12 0.416667 0.843373
96 25A 0.415493 0.851852
97 AMP MG 0.415385 0.785714
98 COD 0.415094 0.842697
99 ADP BEF 0.414815 0.77907
100 BEF ADP 0.414815 0.77907
101 4TC 0.412903 0.879518
102 APC 0.411765 0.843373
103 NB8 0.410959 0.835294
104 ME8 0.410959 0.806818
105 1ZZ 0.410959 0.806818
106 4UW 0.409091 0.825581
107 NAX 0.409091 0.837209
108 RBY 0.408759 0.843373
109 ADV 0.408759 0.843373
110 ADP MG 0.407407 0.797619
111 P1H 0.405882 0.818182
112 OOB 0.405594 0.864198
113 A A 0.40411 0.829268
114 LAD 0.40411 0.825581
115 UPA 0.403846 0.86747
116 4UU 0.401316 0.833333
117 A3D 0.401235 0.876543
118 DLL 0.4 0.864198
119 XAH 0.4 0.806818
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2A8X; Ligand: FAD; Similar sites found: 377
This union binding pocket(no: 1) in the query (biounit: 2a8x.bio1) has 44 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5M67 3D1 0.001665 0.4028 1.2931
2 5M67 NAD 0.001698 0.4025 1.2931
3 3HDY FAD 0.000002245 0.51111 1.51134
4 3HDY GDU 0.000002437 0.51086 1.51134
5 3HDY FDA 0.000002282 0.51086 1.51134
6 5BXV MGP 0.04328 0.41869 1.5625
7 1EJ4 M7G 0.03791 0.4275 1.57895
8 5G3U FDA 0.0000002068 0.511 1.65485
9 5G3U ITW 0.000001615 0.4985 1.65485
10 5EB4 FAD 0.0000003007 0.51171 1.72414
11 1UWK URO 0.0007241 0.41201 1.72414
12 1UWK NAD 0.0007241 0.41201 1.72414
13 3AXB FAD 0.0000008807 0.52721 1.78571
14 3AXB PRO 0.000002427 0.49448 1.78571
15 1HDG NAD 0.0007382 0.45345 1.80723
16 3OA2 NAD 0.003682 0.41588 1.88679
17 2FK8 SAM 0.01077 0.41485 1.88679
18 3GDN HBX 0.0000007195 0.51798 1.93966
19 3GDN FAD 0.0000003771 0.51477 1.93966
20 2BH9 NAP 0.01128 0.42665 1.93966
21 1UXG NAD 0.0006118 0.40131 1.94175
22 2B5W NAP 0.003013 0.40521 1.96078
23 3JV7 NAD 0.0002688 0.45847 2.02899
24 4ZCC NAI 0.0000001858 0.53781 2.08333
25 4ZCC FAD 0.0000001858 0.53781 2.08333
26 1KPG SAH 0.011 0.41159 2.09059
27 1QMG APX 0.006495 0.41892 2.15517
28 3L9W AMP 0.000122 0.40211 2.17918
29 1VQW FAD 0.00000005275 0.50606 2.18818
30 2GV8 FAD 0.0000000148 0.52767 2.23714
31 2GVC FAD 0.00000001111 0.52675 2.23714
32 3WGT QSC 0.000004791 0.48789 2.30548
33 3WGT FAD 0.000004827 0.48658 2.30548
34 1E1M FAD 0.00000009268 0.55061 2.37069
35 4Z24 FAD 0.0000001175 0.53134 2.37069
36 1E1M NAP 0.00000009268 0.49704 2.37069
37 1M2W NAD 0.007888 0.41521 2.37069
38 2I3G NAP 0.003261 0.41303 2.37069
39 4YCA NDP 0.0001124 0.4842 2.38095
40 2GMP NAG MAN 0.01246 0.44269 2.38095
41 2PHW MAN MAN MAN BMA MAN MAN MAN 0.009884 0.44113 2.38095
42 2GMM MAN MAN 0.02037 0.42533 2.38095
43 1NF8 BOG 0.04278 0.41643 2.41546
44 5EOW FAD 0.00000001301 0.52855 2.46914
45 2IXB NAD 0.0008181 0.43649 2.47748
46 2IXB A2G 0.002122 0.40435 2.47748
47 3G5S FAD 0.00000001132 0.54366 2.48307
48 1MUU NAD 0.00004006 0.40133 2.52294
49 3E3U NVC 0.02414 0.41354 2.53807
50 4EI7 GDP 0.01341 0.40772 2.57069
51 4G74 FAD 0.000000002627 0.62257 2.58621
52 1QO8 FAD 0.000000009507 0.5669 2.58621
53 4G74 UQ5 0.00000002469 0.5353 2.58621
54 1GPE FAD 0.000000507 0.51651 2.58621
55 3VPH OXM 0.0002726 0.40346 2.58621
56 3QJ4 FAD 0.00000006343 0.56363 2.63158
57 4YUW S4M 0.01034 0.40082 2.63158
58 4YUW 4JU 0.01061 0.40082 2.63158
59 3GMB FAD 0.0000001327 0.49959 2.6506
60 3BAZ NAP 0.002341 0.43223 2.7027
61 1MV8 NAD 0.00004429 0.40034 2.75229
62 4DMG SAM 0.002568 0.46711 2.79898
63 1VKO NAD 0.004442 0.40549 2.80172
64 3VYW SAM 0.001165 0.45881 2.92208
65 1XDS SAM 0.01298 0.42719 2.94118
66 1D4D FAD 0.00000001484 0.56407 2.97203
67 1XCL SAH 0.00139 0.4249 2.97872
68 1VL8 NAP 0.005323 0.40028 2.99625
69 1J0X NAD 0.001161 0.40324 3.01205
70 1PS9 FAD 0.00000000009335 0.628 3.01724
71 1YY5 FAD 0.000000004356 0.58327 3.01724
72 1RSG FAD 0.00000001067 0.5653 3.01724
73 5MBX SP5 0.0000001579 0.54401 3.01724
74 5MBX FAD 0.0000001579 0.54401 3.01724
75 4YNU FAD 0.0000002142 0.52745 3.01724
76 4YNU LGC 0.0000003258 0.52698 3.01724
77 3Q9T FAY 0.000001656 0.48189 3.01724
78 1X8X TYR 0.04135 0.40818 3.10559
79 1Q9I TEO 0.00000002209 0.5757 3.15236
80 1Q9I FAD 0.00000002209 0.50154 3.15236
81 2F1K NAP 0.00006315 0.49462 3.22581
82 2GMH FAD 0.000000003981 0.59176 3.23276
83 4IV9 FAD 0.00000004771 0.55945 3.23276
84 1PN0 IPH 0.00000004151 0.55694 3.23276
85 1PN0 FAD 0.00000003901 0.55639 3.23276
86 5EVY FAD 0.000009771 0.54261 3.23276
87 5HSA FAS 0.000006945 0.47128 3.23276
88 4GR5 APC 0.0232 0.40805 3.23276
89 3K7M FAD 0.0000001574 0.48969 3.24826
90 3G2O SAM 0.007372 0.42875 3.34448
91 4YRY FAD 0.000000002219 0.58741 3.44828
92 4YRY NAD 0.000000009239 0.5846 3.44828
93 4DSG FAD 0.0000005272 0.53184 3.44828
94 4DSG UDP 0.0000005272 0.53184 3.44828
95 2VVM FAD 0.0000001037 0.52658 3.44828
96 4EIP FAD 0.0000003096 0.52501 3.44828
97 4EIP K2C 0.0000003096 0.52501 3.44828
98 2VVL FAD 0.0000001638 0.52396 3.44828
99 5J7X FAD 0.0000001585 0.51341 3.44828
100 4MOP 2H5 0.00000125 0.51109 3.44828
101 2HJR APR 0.000424 0.47089 3.44828
102 1JQ3 AAT 0.002247 0.41448 3.44828
103 1NPD NAD 0.00179 0.44026 3.47222
104 1NVM NAD 0.0005596 0.44292 3.47826
105 2RGJ FAD 0.00000001589 0.5238 3.48259
106 1KOL NAD 0.0001415 0.4138 3.51759
107 1CER NAD 0.0002926 0.46692 3.62538
108 3E1T FAD 0.000000002941 0.58717 3.66379
109 2JB2 FAD 0.000000169 0.54459 3.66379
110 2JB2 PHE 0.0000002138 0.53715 3.66379
111 3UCL NAP 0.000001047 0.52851 3.66379
112 3UCL CYH 0.0000008687 0.52845 3.66379
113 3UCL FAD 0.0000008687 0.52845 3.66379
114 4AP3 FAD 0.000001083 0.52104 3.66379
115 4AP3 NAP 0.000001083 0.52104 3.66379
116 1KNR FAD 0.0000001812 0.51875 3.66379
117 1DJN ADP 0.0000000002588 0.51841 3.66379
118 3NYC IAR 0.000003993 0.49289 3.67454
119 3NYC FAD 0.000003993 0.49289 3.67454
120 5TUK FAD 0.0000002349 0.4653 3.67647
121 3GFB NAD 0.0001619 0.47402 3.71429
122 5BUK FAD 0.00000001256 0.5681 3.77778
123 3NKS FAD 0.00000006998 0.56647 3.87931
124 1H82 GZZ 0.0000001227 0.55484 3.87931
125 1H82 FAD 0.00000008262 0.55484 3.87931
126 2WET FAD 0.0000001132 0.5287 3.87931
127 4D04 NAP 0.000001125 0.52253 3.87931
128 4D04 FAD 0.000001125 0.52253 3.87931
129 4USR FAD 0.00000007498 0.50589 3.87931
130 2Y6Q I7T 0.0000014 0.50322 3.87931
131 1N4W FAD 0.00000124 0.5009 3.87931
132 2Y6Q FAD 0.0000001481 0.49015 3.87931
133 2IID FAD 0.0000001487 0.48689 3.87931
134 2IID PHE 0.0000001487 0.48689 3.87931
135 5JJR SAH 0.01224 0.41831 3.87931
136 5HJM MTA 0.01337 0.41346 3.87931
137 5AYV KPL 0.0003453 0.40087 3.87931
138 4K5S PM0 0.000003171 0.49389 3.91791
139 4K5S FAD 0.0000001867 0.4909 3.91791
140 2NXE SAM 0.006505 0.43132 3.93701
141 4D7E FAD 0.00001814 0.44369 3.9627
142 4NAE 1GP 0.0308 0.4238 4
143 4X9M FAD 0.0000009286 0.49577 4.06699
144 4FWE FAD 0.000000007665 0.5735 4.09483
145 2Z3Y F2N 0.00000002013 0.55972 4.09483
146 4YSX FAD 0.00000001985 0.54912 4.09483
147 3WE0 FAD 0.0000001354 0.53251 4.09483
148 2X3N FAD 0.00000006322 0.52073 4.09483
149 1Y8Q ATP 0.00003516 0.51374 4.09483
150 5WGR FAD 0.0000002919 0.51185 4.09483
151 2NU5 NAG 0.03053 0.40113 4.09836
152 3B1J NAD 0.0006045 0.44451 4.12979
153 1O94 ADP 0.0000000001118 0.53441 4.16667
154 1Z82 NDP 0.00689 0.40729 4.1791
155 2B9W FAD 0.00000008041 0.55525 4.24528
156 2ZXI FAD 0.00000001633 0.58904 4.31034
157 3UOY NAP 0.00000111 0.52667 4.31034
158 3UOY FAD 0.00000111 0.52667 4.31034
159 2AQJ FAD 0.0000009655 0.52169 4.31034
160 2AQJ TRP 0.0000009902 0.52023 4.31034
161 2BRY FAD 0.00000003236 0.51223 4.31034
162 5FJN BE2 0.0000007909 0.51011 4.31034
163 5MQ6 NDP 0.00005561 0.50954 4.31034
164 3IHG FAD 0.00000001271 0.50617 4.31034
165 4TXI FAD 0.00000004365 0.50367 4.31034
166 5FJN FAD 0.000001177 0.49857 4.31034
167 1COY FAD 0.000002933 0.49494 4.31034
168 4C3Y FAD 0.000001435 0.49333 4.31034
169 4C3Y ANB 0.000003146 0.49153 4.31034
170 1GTE FAD 0.00000005467 0.47983 4.31034
171 1GQ2 NAP 0.0009774 0.4391 4.31034
172 4U8P FDA 0.0000006392 0.43819 4.31034
173 1COY AND 0.000006146 0.43622 4.31034
174 4U8P UDP 0.0000007245 0.43184 4.31034
175 2HI4 BHF 0.02696 0.40487 4.31034
176 1YKJ FAD 0.000003768 0.50429 4.31472
177 1YKJ PHB 0.000003768 0.50429 4.31472
178 3ZNN FAD 0.000005696 0.4931 4.32277
179 3ZNN 4WL 0.000005696 0.4931 4.32277
180 5H81 NAP 0.00274 0.43858 4.37018
181 5I39 FAD 0.0000009403 0.48836 4.41176
182 2YG3 FAD 0.000000008728 0.5614 4.41501
183 2QV7 ADP 0.0115 0.42624 4.45104
184 2VOH CIT 0.04376 0.41294 4.4586
185 3DMH SAM 0.006514 0.42481 4.46194
186 4RPL FAD 0.0000004169 0.53856 4.51128
187 4RPL 3UC 0.0000006742 0.53427 4.51128
188 5TS5 FAD 0.00000002241 0.56642 4.52586
189 4REP FAD 0.00000001576 0.54864 4.52586
190 3AYI HCI 0.0000001698 0.54169 4.52586
191 3AYI FAD 0.0000001557 0.54169 4.52586
192 2DKH FAD 0.00000001556 0.52295 4.52586
193 2DKH 3HB 0.0000001431 0.51801 4.52586
194 4AT0 FAD 0.000001372 0.5048 4.52586
195 5EZ7 FAD 0.000001137 0.49052 4.59184
196 1E3W NAD 0.003857 0.41258 4.5977
197 2JJQ SAH 0.01397 0.42558 4.70588
198 1REO FAD 0.00000004161 0.53491 4.73251
199 1NAA 6FA 0.0000008116 0.50695 4.74138
200 1NAA ABL 0.00000132 0.46379 4.74138
201 4OPC PGT 0.0000006322 0.55997 4.85651
202 4OPC FDA 0.000000492 0.55919 4.85651
203 4BJZ P3A 0.000001157 0.52883 4.95283
204 4BJZ FAD 0.0007804 0.46036 4.95283
205 4HA6 FAD 0.0000009967 0.50402 4.9569
206 1RYI FAD 0.000001033 0.49759 4.97382
207 1RYI GOA 0.001755 0.42753 4.97382
208 3WMX NAD 0.003739 0.42085 5.02793
209 1JG3 ADN 0.0005923 0.48047 5.10638
210 4CNK FAD 0.00000002104 0.53976 5.11509
211 4Q3F TLA 0.04178 0.40515 5.12821
212 5BVA FAD 0.000000004161 0.58393 5.13447
213 3ABI NAD 0.0003273 0.45508 5.20548
214 1Y9Q MED 0.03541 0.41728 5.20833
215 3FPZ AHZ 0.0009446 0.4609 5.21472
216 2RGO FAD 0.000002433 0.47376 5.27183
217 4JNA FAD 0.000000009135 0.56743 5.29412
218 1RL4 BRR 0.01648 0.43788 5.31915
219 5BR7 FAD 0.0000004072 0.5368 5.34351
220 5BR7 FLC 0.000001871 0.51385 5.34351
221 4NTC FAD 0.000000002219 0.58311 5.37313
222 4NTD FAD 0.000000005579 0.55807 5.38793
223 4J36 1HR 0.000001278 0.50047 5.38793
224 4J36 FAD 0.0000001371 0.49575 5.38793
225 2Q0L FAD 0.0000000006796 0.61768 5.46624
226 2Q0L NAP 0.0003823 0.49896 5.46624
227 1E6E FAD 0.00000003293 0.52798 5.46875
228 2C7G FAD 0.00000006556 0.55827 5.48246
229 2C7G ODP 0.0000001626 0.54357 5.48246
230 2R4J 13P 0.000002203 0.50277 5.58882
231 2R4J FAD 0.000002203 0.46073 5.58882
232 2RGH FAD 0.000002569 0.48176 5.6042
233 5JE8 NAD 0.0005677 0.45828 5.62914
234 1ELI PYC 0.0001702 0.4189 5.65553
235 2DT5 NAD 0.000424 0.45371 5.6872
236 3LU1 NAD 0.002696 0.41876 5.76923
237 2E5V FAD 0.0000001629 0.52987 5.81897
238 3OFK SAH 0.01304 0.40826 6.01852
239 3OJO NAD 0.00001394 0.40024 6.03248
240 5TUF FAD 0.0000003363 0.56389 6.11247
241 5TUF TDC 0.000001913 0.44244 6.11247
242 5N53 8NB 0.003924 0.47514 6.15385
243 3S5W FAD 0.0000003586 0.47512 6.2635
244 1RP0 AHZ 0.00000002072 0.51067 6.33803
245 1DLJ NAI 0.0003794 0.42526 6.46766
246 1DLJ UGA 0.0008798 0.41299 6.46766
247 2VDV SAM 0.01088 0.43105 6.50407
248 3ITJ FAD 0.000000001723 0.60322 6.50888
249 4UP3 FAD 0.0000000007637 0.59489 6.6879
250 4K28 NAD 0.00008453 0.49327 6.69145
251 2F5X ASP 0.04124 0.41566 6.73077
252 4RSL FAD 0.00001395 0.44823 6.74157
253 3EGV SAH 0.003243 0.44938 6.80272
254 5JCA FAD 0.000000000619 0.60537 6.89655
255 5JCA NDP 0.00000001031 0.59211 6.89655
256 2CUL FAD 0.00000006102 0.51513 6.89655
257 3LST SAH 0.03673 0.4075 6.89655
258 4USQ FAD 0.00000004324 0.51739 6.92521
259 1TDF FAD 0.0000000004866 0.61821 6.96203
260 1TDF NAP 0.000000003532 0.6178 6.96203
261 1LDM NAD 0.0008639 0.43837 6.99088
262 4MIG G3F 0.0000006282 0.51743 7.11207
263 1Z45 NAD 0.005042 0.40796 7.11207
264 5ODQ FAD 0.000000004261 0.57818 7.14286
265 3TLJ SAH 0.01845 0.4015 7.23861
266 2QA1 FAD 0.0000000077 0.61075 7.32759
267 1KEV NDP 0.001215 0.42212 7.40741
268 3QVP FAD 0.0000002547 0.52349 7.97414
269 2G77 AF3 0.04568 0.41347 8.04878
270 3OZ2 FAD 0.000000005569 0.56646 8.06045
271 4GUS FAD 0.00000000849 0.57371 8.06452
272 4GUT FAD 0.0000000138 0.56992 8.06452
273 4HSU FAD 0.00000002672 0.55728 8.06452
274 1I8T FAD 0.0000004971 0.50191 8.17439
275 4RDH AMP 0.00004658 0.54386 8.33333
276 5UAO FAD 0.0000002245 0.50917 8.40517
277 3JUC PCA 0.03476 0.40785 8.49673
278 1XHC FAD 0.00000000003946 0.61436 8.71935
279 2IVD FAD 0.00000004497 0.57789 8.78661
280 2IVD ACJ 0.04753 0.40493 8.78661
281 3AD8 NAD 0.00000000004109 0.60262 8.91089
282 3AD8 PYC 0.00001928 0.48229 8.91089
283 3AD8 FAD 0.00001928 0.48229 8.91089
284 5TTJ FAD 0.00000008237 0.52679 9.05172
285 1HKU NAD 0.0003335 0.4517 9.21788
286 3T31 DCQ 0.00000008508 0.55564 9.26724
287 3T31 FAD 0.00000007471 0.55507 9.26724
288 2VHW NAI 0.0001691 0.41071 9.26724
289 1C1X NAD 0.0002877 0.46722 9.29577
290 3GF4 FAD 0.000003047 0.45157 9.48718
291 3GF4 UPG 0.000002339 0.44439 9.48718
292 4MO2 FDA 0.0000001878 0.55117 9.51087
293 4MO2 FAD 0.0000002155 0.54493 9.51087
294 1BW9 NAD 0.0001719 0.49223 9.55056
295 5MZI FAD 0.000000972 0.52159 9.69828
296 5MZI FYK 0.000001089 0.52095 9.69828
297 5JWC FAD 0.000000000637 0.57356 9.78887
298 1JNR FAD 0.0000000663 0.57573 10
299 1LSS NAD 0.000005091 0.40132 10
300 3A27 SAM 0.002479 0.45112 10.2941
301 3NJ4 NAD 0.008524 0.4088 10.3448
302 1E3I CXF 0.001871 0.41059 10.3723
303 3G89 SAM 0.001338 0.4768 10.4418
304 3LZW NAP 0.00000003182 0.57152 11.1446
305 3LZW FAD 0.000000002246 0.57026 11.1446
306 1FL2 FAD 0.00000000008148 0.62113 12.2845
307 2CJU PHX 0.01368 0.44553 12.3967
308 5KMS FAD 0.000000001124 0.57109 12.7155
309 5KMS NAD 0.0000000523 0.56411 12.7155
310 3AB1 FAD 0.000000001575 0.61015 14.0086
311 1EZ4 NAD 0.0003505 0.46365 14.1509
312 3GDH SAH 0.005125 0.42056 14.5228
313 2XVF FAD 0.00000002932 0.53177 14.6552
314 2XVE FAD 0.0000003818 0.53668 14.8707
315 2GAG NAD 0.0000000000177 0.63011 15.1515
316 2GAG FAD 0.000008752 0.47554 15.1515
317 2GAG FOA 0.00001575 0.46708 15.1515
318 1VDC FAD 0.000000002202 0.59805 15.3153
319 4BV6 FAD 0.00000000138 0.59063 18.319
320 4TM3 FAD 0.00000401 0.50798 18.319
321 3GD4 NAD 0.000000009247 0.6062 18.75
322 3GD4 FAD 0.000000004358 0.60119 18.75
323 3LXD FAD 0.0000000002597 0.58587 20.4741
324 3CTY FAD 0.00000000002149 0.65938 20.6897
325 2CDU FAD 0.000000001688 0.56714 20.7965
326 2CDU ADP 0.0000003023 0.41145 20.7965
327 1Q1R FAD 0.0000000008775 0.63437 20.8817
328 3FG2 FAD 0.0000000006693 0.56279 21.5347
329 2V3A FAD 0.000000002197 0.57235 21.9828
330 2V3B FAD 0.000000002212 0.56697 21.9828
331 5JCM FAD 0.000000008877 0.5968 22.1983
332 5JCM ISD 0.000000009598 0.5968 22.1983
333 5JCM NAD 0.000000009598 0.5968 22.1983
334 2YVF NAD 0.00000003237 0.5749 22.7941
335 2YVF FAD 0.0000000299 0.5749 22.7941
336 2YVJ FAD 0.000000001945 0.56924 22.7941
337 2YVJ NAI 0.000001255 0.40534 22.7941
338 2NPX FAD 0.000000001039 0.63174 25
339 4EMI NAD 0.000000001437 0.62046 25
340 4EMI FAD 0.0000000001767 0.60599 25
341 4EMJ FAD 0.0000000003722 0.60034 25
342 2NPX NAD 0.000000008061 0.50752 25
343 3ICR FAD 0.0000000003549 0.59155 25.2155
344 3ICS FAD 0.0000000005708 0.59012 25.2155
345 3ICT FAD 0.0000000009314 0.57895 25.2155
346 3ICT ADP 0.00000006346 0.40083 25.2155
347 1YQZ FAD 0.00000001105 0.58858 25.8621
348 3CGB FAD 0.0000000005772 0.58617 26.7241
349 3KLJ FAD 0.0000000000827 0.59147 26.7532
350 5J60 FAD 0.0000000003048 0.6069 26.9397
351 3F8D FAD 0.000000008813 0.60375 28.4483
352 3CGD FAD 0.00000002055 0.59683 29.0948
353 3CGD NAD 0.00000002055 0.59683 29.0948
354 3CGD COA 0.00000002055 0.59683 29.0948
355 3NTA FAD 0.000000001628 0.61962 30.1724
356 3NT6 FAD 0.0000000007688 0.58564 30.1724
357 3NTD FAD 0.000000001337 0.57821 31.25
358 5VN0 FAD 0.00000000208 0.61587 31.4655
359 5VN0 NAI 0.00000004224 0.48675 31.4655
360 2Q7V FAD 0.00000000008131 0.6298 35.0769
361 1MO9 FAD 0.000000000002671 0.73745 40.7328
362 1MO9 KPC 0.000000000003224 0.73575 40.7328
363 4J56 FAD 0.00000000000003042 0.7534 43.319
364 2HQM FAD 0.00000000000000755 0.76532 43.75
365 1GET NAP 0.000000000000008216 0.81379 44.8889
366 1GET FAD 0.00000000000000655 0.81379 44.8889
367 1FEC FAD 0.00000000000004063 0.75379 45.2586
368 2V6O FAD 0.000000000002076 0.54343 45.2586
369 2WPF FAD 0.0000000000001006 0.80384 45.4741
370 2WPF WPF 0.0000000000001626 0.79959 45.4741
371 3QFA FAD 0.00000000000001699 0.76616 45.4741
372 1BZL FAD 0.00000000000128 0.76429 45.4741
373 1ZK7 FAD 0.00000000000003186 0.73248 45.4741
374 2NVK FAD 0.0000000000002429 0.71097 45.4741
375 3SQP FAD 0.0000000000006708 0.81792 46.1207
376 2RAB NAD 0.00000000000003042 0.79054 47.0842
377 2RAB FAD 0.000000000000006772 0.77498 47.0842
Pocket No.: 2; Query (leader) PDB : 2A8X; Ligand: FAD; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2a8x.bio1) has 44 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Feedback