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Receptor
PDB id Resolution Class Description Source Keywords
2A8X 2.4 Å EC: 1.8.1.4 CRYSTAL STRUCTURE OF LIPOAMIDE DEHYDROGENASE FROM MYCOBACTERIUM TUBERCULOSIS MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE; PYRUVATE DEHYDROGENASE; ALPHA KETO ACID DEHYDROGENASE; MYCOBACTERIUM TUBERCULOSIS OXIDOREDUCTASE
Ref.: CRYSTAL STRUCTURE AND FUNCTIONAL ANALYSIS OF LIPOAMIDE DEHYDROGENASE FROM MYCOBACTERIUM TUBERCULOSIS J.BIOL.CHEM. V. 280 33977 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FAD A:480;
B:580;
Valid;
Valid;
none;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
MPD A:590;
Invalid;
none;
submit data
118.174 C6 H14 O2 C[C@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2A8X 2.4 Å EC: 1.8.1.4 CRYSTAL STRUCTURE OF LIPOAMIDE DEHYDROGENASE FROM MYCOBACTERIUM TUBERCULOSIS MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE; PYRUVATE DEHYDROGENASE; ALPHA KETO ACID DEHYDROGENASE; MYCOBACTERIUM TUBERCULOSIS OXIDOREDUCTASE
Ref.: CRYSTAL STRUCTURE AND FUNCTIONAL ANALYSIS OF LIPOAMIDE DEHYDROGENASE FROM MYCOBACTERIUM TUBERCULOSIS J.BIOL.CHEM. V. 280 33977 2005
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 10 families.
1 2A8X - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 2A8X - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2A8X - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 2F5Z - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FAD; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 FAD 1 1
2 FAS 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 FAE 0.751773 0.987654
7 SFD 0.651007 0.860215
8 FDA 0.641892 0.906977
9 FNK 0.602564 0.876405
10 62F 0.572327 0.939024
11 F2N 0.566265 0.886364
12 FMN 0.543307 0.876543
13 FA9 0.526316 0.939759
14 6YU 0.516304 0.860215
15 P6G FDA 0.511628 0.908046
16 FAD NBT 0.508876 0.83871
17 A2D 0.504065 0.875
18 P5F 0.491329 0.941176
19 FAD CNX 0.488506 0.8125
20 AR6 0.488372 0.851852
21 APR 0.488372 0.851852
22 AGS 0.484615 0.811765
23 SAP 0.484615 0.811765
24 M33 0.484375 0.864198
25 BA3 0.484127 0.875
26 HEJ 0.48062 0.851852
27 ATP 0.48062 0.851852
28 ADP 0.480315 0.851852
29 B4P 0.480315 0.875
30 AP5 0.480315 0.875
31 ANP 0.477273 0.831325
32 AQP 0.476923 0.851852
33 5FA 0.476923 0.851852
34 48N 0.469388 0.902439
35 OAD 0.467626 0.876543
36 9X8 0.467626 0.833333
37 FAD NBA 0.467033 0.793814
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AT4 0.465116 0.821429
41 AD9 0.462121 0.831325
42 3OD 0.460993 0.876543
43 RBF 0.460938 0.790123
44 FB0 0.460606 0.835165
45 139 0.460526 0.858824
46 AP0 0.46 0.835294
47 A22 0.459854 0.864198
48 ACP 0.458015 0.853659
49 8QN 0.456522 0.864198
50 PRX 0.454545 0.831325
51 A3R 0.453237 0.86747
52 A1R 0.453237 0.86747
53 G3A 0.452055 0.902439
54 T5A 0.45098 0.872093
55 G5P 0.44898 0.902439
56 ATF 0.448529 0.821429
57 50T 0.44697 0.819277
58 6YZ 0.445255 0.853659
59 ACQ 0.444444 0.853659
60 CNV FAD 0.443182 0.917647
61 ADQ 0.442857 0.853659
62 PAJ 0.442857 0.847059
63 5AL 0.441176 0.864198
64 ADX 0.439394 0.775281
65 CA0 0.439394 0.853659
66 A4P 0.437909 0.831461
67 25L 0.4375 0.864198
68 P33 FDA 0.436464 0.817204
69 5SV 0.435714 0.793103
70 OMR 0.434211 0.818182
71 TXE 0.434211 0.890244
72 ABM 0.434109 0.829268
73 A 0.433071 0.82716
74 AMP 0.433071 0.82716
75 4AD 0.432624 0.855422
76 ADJ 0.432258 0.818182
77 B5M 0.431507 0.878049
78 B5Y 0.431507 0.878049
79 BIS 0.430556 0.802326
80 SRA 0.429688 0.788235
81 AFH 0.42953 0.825581
82 NXX 0.427632 0.865854
83 DND 0.427632 0.865854
84 UP5 0.427632 0.878049
85 6V0 0.427632 0.857143
86 TXD 0.427632 0.890244
87 DQV 0.426667 0.8875
88 SRP 0.42446 0.843373
89 PR8 0.423611 0.837209
90 T99 0.423358 0.821429
91 TAT 0.423358 0.821429
92 AMO 0.422535 0.865854
93 TXA 0.42069 0.865854
94 FYA 0.42069 0.864198
95 PTJ 0.42069 0.835294
96 CNA 0.420382 0.865854
97 00A 0.41958 0.823529
98 AHX 0.41958 0.835294
99 MAP 0.41844 0.811765
100 NAI 0.418301 0.845238
101 AU1 0.41791 0.831325
102 A12 0.416667 0.843373
103 AP2 0.416667 0.843373
104 25A 0.415493 0.851852
105 9ZA 0.415493 0.845238
106 9ZD 0.415493 0.845238
107 COD 0.415094 0.842697
108 4TC 0.412903 0.879518
109 APC 0.411765 0.843373
110 ME8 0.410959 0.806818
111 1ZZ 0.410959 0.806818
112 NB8 0.410959 0.835294
113 4UW 0.409091 0.825581
114 NAX 0.409091 0.837209
115 F2R 0.408805 0.850575
116 RBY 0.408759 0.843373
117 ADV 0.408759 0.843373
118 P1H 0.405882 0.818182
119 OOB 0.405594 0.864198
120 LAD 0.40411 0.825581
121 A A 0.40411 0.829268
122 UPA 0.403846 0.86747
123 4UU 0.401316 0.833333
124 GA7 0.401316 0.865854
125 A3D 0.401235 0.876543
126 80F 0.401235 0.808989
127 XAH 0.4 0.806818
128 DLL 0.4 0.864198
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2A8X; Ligand: FAD; Similar sites found with APoc: 936
This union binding pocket(no: 1) in the query (biounit: 2a8x.bio1) has 44 residues
No: Leader PDB Ligand Sequence Similarity
1 6BOC RIM None
2 6FX2 FUC C4W NAG BMA MAN NAG GAL None
3 2PV7 NAD 1.00671
4 1V8B NAD 1.2931
5 5M67 3D1 1.2931
6 5M67 NAD 1.2931
7 4HXY NDP 1.36986
8 4N49 SAM 1.40187
9 5WP5 SAH 1.42566
10 3TWO NDP 1.43678
11 6DNT NAD 1.45349
12 5AOV NAP 1.4881
13 2Q1W NAD 1.5015
14 3HDY FAD 1.51134
15 3HDY FDA 1.51134
16 3HDY GDU 1.51134
17 5BXV MGP 1.5625
18 1EJ4 M7G 1.57895
19 6F7L FAD 1.58371
20 5I34 GDP 1.5873
21 3MAG SAH 1.62866
22 1SQF SAM 1.6317
23 5G3U FDA 1.65485
24 5G3U ITW 1.65485
25 3MCT SAH 1.6835
26 5EB4 FAD 1.72414
27 3CBG SAH 1.72414
28 4B63 FAD 1.72414
29 4B63 ORN 1.72414
30 4B63 NAP 1.72414
31 5FAW CHT 1.72414
32 3KAL HGS 1.72414
33 2HHP FLC 1.72414
34 1UWK NAD 1.72414
35 1UWK URO 1.72414
36 2B4R AES 1.73913
37 2B4R NAD 1.73913
38 3AXB FAD 1.78571
39 3AXB PRO 1.78571
40 3DUW SAH 1.79372
41 1HDG NAD 1.80723
42 1P9B HDA 1.80995
43 6C8R SAH 1.84697
44 3OA2 NAD 1.88679
45 2FK8 SAM 1.88679
46 1GR0 NAD 1.90736
47 1N1G BCP 1.91257
48 3GDN FAD 1.93966
49 3GDN HBX 1.93966
50 3PT9 SAH 1.93966
51 1UXG NAD 1.94175
52 1UXG FUM 1.94175
53 2B5W NAP 1.96078
54 1YKF NAP 1.98864
55 1LVG ADP 2.0202
56 3H9E NAD 2.02312
57 2D3S TNR 2.06612
58 3V1Y NAD 2.07715
59 1CF2 NAP 2.07715
60 4ZCC NAI 2.08333
61 4ZCC FAD 2.08333
62 1NVT NAP 2.09059
63 1KPG SAH 2.09059
64 2HNK SAH 2.09205
65 1WG8 SAM 2.10526
66 1FWY UD1 2.1148
67 1B8U NAD 2.12766
68 1FP1 SAH 2.15054
69 5ZYN FAD 2.15517
70 6ER9 FAD 2.15517
71 6ER9 NAP 2.15517
72 5M60 BGC 2.15517
73 1QMG APX 2.15517
74 4DCT GDP 2.15517
75 2WME NAP 2.15517
76 1UP7 NAD 2.15827
77 3L9W AMP 2.17918
78 3L9W GSH 2.17918
79 1F3L SAH 2.18069
80 5BJX NAD 2.18579
81 5BJX UDP 2.18579
82 1VQW FAD 2.18818
83 1PJS NAD 2.18818
84 3CIF NAD 2.22841
85 1H2B NAJ 2.22841
86 3CIF G3H 2.22841
87 5A1S FLC 2.23214
88 2GVC FAD 2.23714
89 2GV8 FAD 2.23714
90 2GV8 NDP 2.23714
91 1FWV SGA MAG FUC 2.23881
92 5ARK UMP 2.23881
93 3WBF NAP 2.29508
94 3WBF API 2.29508
95 3WGT FAD 2.30548
96 3WGT QSC 2.30548
97 5E72 SAM 2.31214
98 1P31 EPU 2.31579
99 1P3D UMA 2.31579
100 5Z20 NAI 2.31884
101 4Z24 FAD 2.37069
102 1E1M NAP 2.37069
103 1E1M FAD 2.37069
104 6C4N NAP 2.37069
105 1LJ8 NAD 2.37069
106 3CB2 GDP 2.37069
107 3HNC TTP 2.37069
108 1M2W NAD 2.37069
109 2I3G NAP 2.37069
110 4TVD BGC 2.37069
111 4YCA NDP 2.38095
112 1Q8Q MAN MMA 2.38095
113 1Q8O MAN MMA 2.38095
114 2PHU MAN MAN 2.38095
115 1Q8P MAN MMA 2.38095
116 2AUY NAG MAN MMA 2.38095
117 2AR6 NAG MAN 2.38095
118 2PHU MAN MAN MAN BMA MAN 2.38095
119 2PHW MAN MAN MAN BMA MAN MAN MAN 2.38095
120 2GMP NAG MAN 2.38095
121 2GMM MAN MAN 2.38095
122 2GNM MAN 2.38095
123 1Q8V MAN MAN MAN 2.38095
124 2PHX MAN MAN MAN MAN 2.38095
125 3V1U NAD 2.38095
126 2DBZ NAP 2.39521
127 5NUF NAD 2.40964
128 1SZ2 BGC 2.40964
129 5NUE NAD 2.40964
130 1NF8 BOG 2.41546
131 1NV8 MEQ 2.46479
132 1NV8 SAM 2.46479
133 5EOW FAD 2.46914
134 1SC6 NAD 2.47525
135 2IXB NAD 2.47748
136 2IXB A2G 2.47748
137 3G5S FAD 2.48307
138 1OMO NAD 2.48447
139 1MUU NAD 2.52294
140 3E3U NVC 2.53807
141 1U1I NAD 2.55102
142 3LCC SAH 2.55319
143 5X68 FAD 2.55754
144 4ZRN NAD 2.5641
145 4EI7 GDP 2.57069
146 1QO8 FAD 2.58621
147 1GPE FAD 2.58621
148 3VPH NAD 2.58621
149 3X0D SAH 2.58621
150 3VPH OXM 2.58621
151 5N2I NAP 2.58621
152 2WZF BGC 2.58621
153 1HYH NAD 2.589
154 5KVS NAP 2.5974
155 2P41 SAH 2.62295
156 3QJ4 FAD 2.63158
157 4YUW 4JU 2.63158
158 4YUW S4M 2.63158
159 3GMB FAD 2.6506
160 2AG8 NAP 2.6616
161 5AHO TLA 2.67857
162 3ZYR NAG NAG BMA MAN MAN NAG NAG 2.68199
163 3ZYR ASN NAG NAG BMA MAN MAN NAG NAG 2.68199
164 4Z0H NAD 2.69461
165 3BAZ NAP 2.7027
166 1V6A TRE 2.71084
167 5Y8L NAD 2.71186
168 5Y8L HUI 2.71186
169 6ACS CIT 2.71318
170 6BQ6 TER 2.71903
171 2AOT SAH 2.73973
172 2V6G NAP 2.74725
173 1MV8 NAD 2.75229
174 5Z75 NAD 2.75229
175 1XTP SAI 2.75591
176 3B1F NAD 2.75862
177 1WP4 NDP 2.76817
178 1WVG APR 2.78552
179 1TPY SAH 2.78746
180 4DMG SAM 2.79898
181 1FP2 SAH 2.80172
182 1VKO NAD 2.80172
183 3GCZ SAM 2.83688
184 3SSO SAH 2.86396
185 5HXI FAD 2.90237
186 5HXI 5HN 2.90237
187 3EVG SAH 2.90909
188 4NBT NAD 2.91667
189 3VYW SAM 2.92208
190 1AE1 NAP 2.9304
191 5U19 827 2.93255
192 5U19 SAH 2.93255
193 1XDS SAM 2.94118
194 1YXM ADE 2.9703
195 1D4D FAD 2.97203
196 2PX8 SAH 2.97398
197 1XCL SAH 2.97872
198 6AA8 NAD 2.98013
199 4BVA NDP 2.98507
200 4MDH NAD 2.99401
201 1VL8 NAP 2.99625
202 5T63 ALA ALA ALA ALA 2.99728
203 1J49 NAD 3.003
204 1J0X NAD 3.01205
205 1PS9 FAD 3.01724
206 1YY5 FAD 3.01724
207 1RSG FAD 3.01724
208 4YNU FAD 3.01724
209 3Q9T FAY 3.01724
210 4YNU LGC 3.01724
211 5MBX FAD 3.01724
212 5MBX SP5 3.01724
213 1PS9 NAP 3.01724
214 5ERG SAM 3.01724
215 1JG9 GLC 3.01724
216 5OJL TXP 3.02013
217 1H74 ILE 3.04054
218 5E4R NAP 3.06122
219 1R18 SAH 3.0837
220 1Q0S SAH 3.0888
221 3AFN NAP 3.10078
222 1X8X TYR 3.10559
223 2PT9 S4M 3.11526
224 3LKZ SFG 3.11526
225 2PT9 2MH 3.11526
226 1Q9I FAD 3.15236
227 1Q9I TEO 3.15236
228 5CAE COA 3.19489
229 5CAE SIN 3.19489
230 4JJF FE9 3.19767
231 4JJF N2I 3.19767
232 4YT4 FE9 3.2
233 1O5I NAD 3.21285
234 2F1K NAP 3.22581
235 2GMH FAD 3.23276
236 4IV9 FAD 3.23276
237 5EVY FAD 3.23276
238 1PN0 IPH 3.23276
239 1PN0 FAD 3.23276
240 1X87 NAD 3.23276
241 5HSA FAS 3.23276
242 6C4M NAP 3.23276
243 3A06 NDP 3.23276
244 4GR5 APC 3.23276
245 3K7M FAD 3.24826
246 5T48 MGP 3.26087
247 5UGH 8AJ 3.27456
248 6CEP NAD 3.29341
249 6CEP OXM 3.29341
250 5NMX FAD 3.29412
251 5NMX NAP 3.29412
252 5DN9 NAD 3.2967
253 1YJQ NAP 3.30033
254 4CPB GAL CN8 3.30579
255 1N2X SAM 3.32226
256 6C4T NA7 3.33333
257 4YMH SAH 3.33333
258 1VI2 NAD 3.33333
259 2RNF UM3 3.33333
260 3Q3C NAD 3.34448
261 3G2O SAM 3.34448
262 4EUE NAI 3.34928
263 5LD5 NAD 3.35196
264 4TQG NDP 3.40557
265 1I36 NAP 3.40909
266 2CUN 3PG 3.41463
267 5DX8 SFG 3.4384
268 5DWQ SFG 3.4384
269 5DX0 SFG 3.4384
270 5DX1 SFG 3.4384
271 5DXA SFG 3.4384
272 4YRY FAD 3.44828
273 4YRY NAD 3.44828
274 5J7X FAD 3.44828
275 2VVM FAD 3.44828
276 2VVL FAD 3.44828
277 4EIP FAD 3.44828
278 1A5Z NAD 3.44828
279 4MOP 2H5 3.44828
280 4EIP K2C 3.44828
281 2HJR APR 3.44828
282 4DSG UDP 3.44828
283 4DSG FAD 3.44828
284 5DNK SAH 3.44828
285 1JQ3 AAT 3.44828
286 4XQC NAD 3.44828
287 4XQC 13D 3.44828
288 1NPD NAD 3.47222
289 1CDO NAD 3.47594
290 1NVM NAD 3.47826
291 1KGZ PRP 3.47826
292 2RGJ FAD 3.48259
293 4UTU LRY 3.49345
294 4UTW RFW 3.49345
295 1P1C SAH 3.51759
296 1KOL NAD 3.51759
297 2I7C AAT 3.53357
298 5ZW3 SAH 3.55556
299 1RM4 NDP 3.56083
300 1I9G SAM 3.57143
301 3F4F UMP 3.59281
302 2FJK 13P 3.60656
303 5BSH PRO 3.61011
304 2O07 MTA 3.61842
305 2O07 SPD 3.61842
306 1CER NAD 3.62538
307 1L3I SAH 3.64583
308 3E1T FAD 3.66379
309 2JB2 FAD 3.66379
310 1KNR FAD 3.66379
311 2JB2 PHE 3.66379
312 1DJN ADP 3.66379
313 4AP3 FAD 3.66379
314 4AP3 NAP 3.66379
315 3UCL CYH 3.66379
316 3UCL FAD 3.66379
317 2CDC NAP 3.66379
318 2CDC XYP 3.66379
319 2CDC XYS 3.66379
320 3UCL NAP 3.66379
321 3NYC FAD 3.67454
322 3NYC IAR 3.67454
323 5TUK FAD 3.67647
324 5GZ6 NDP 3.68098
325 5GZ6 7C3 3.68098
326 2D2I NAP 3.68421
327 4AF5 CIT 3.68421
328 1QAN SAH 3.68852
329 2EJU SAH 3.7037
330 3GFB NAD 3.71429
331 1X7D NAD 3.71429
332 2VT3 ATP 3.72093
333 5U5G NAP 3.72881
334 1X14 NAD 3.74065
335 5KZD RCJ 3.75427
336 2EG5 SAH 3.76344
337 5BUK FAD 3.77778
338 2YYY NAP 3.79009
339 3AIA SAM 3.79147
340 3U31 NAD 3.7931
341 3GWZ SAH 3.79404
342 2EV9 SKM 3.80228
343 2EV9 NAP 3.80228
344 6C5B SAH 3.81232
345 5W3K NDP 3.82353
346 5W3K 9TY 3.82353
347 5ZI9 FLC 3.84615
348 2Y6P CTP 3.84615
349 1ZQ9 SAM 3.85965
350 4JK3 NAD 3.861
351 4D3F NAP 3.87097
352 1EQ2 NAP 3.87097
353 1SAY PYR 3.87812
354 4USR FAD 3.87931
355 2Y6Q FAD 3.87931
356 3NKS FAD 3.87931
357 2WET FAD 3.87931
358 1H82 FAD 3.87931
359 5AYV NAP 3.87931
360 2IID FAD 3.87931
361 2IID PHE 3.87931
362 2Y6Q I7T 3.87931
363 1H82 GZZ 3.87931
364 5AYV KPL 3.87931
365 4D04 NAP 3.87931
366 4D04 FAD 3.87931
367 5JJR SAH 3.87931
368 5HJM MTA 3.87931
369 5FUB SAH 3.87931
370 1GEG NAD 3.90625
371 5Z21 NAI 3.91061
372 4K5S FAD 3.91791
373 4K5S PM0 3.91791
374 4KIB SAH 3.92157
375 4PLT NAI 3.92749
376 4PLT OXM 3.92749
377 2NXE SAM 3.93701
378 4E5N NAD 3.93939
379 1XG5 NAP 3.94265
380 4D7E FAD 3.9627
381 5N6C NAD 4
382 4RQU NAD 4
383 4NAE 1GP 4
384 4Y1B NAP 4
385 1E5Q NDP 4
386 1P0F NAP 4.02145
387 1VBO MAN MAN MAN 4.02685
388 4W6Z 8ID 4.03458
389 5UAV TFB 4.03727
390 5UAV NDP 4.03727
391 3GEG NAD 4.04858
392 4X9M FAD 4.06699
393 3GRU AMP 4.0678
394 3I51 45C 4.07407
395 4LWP SAH 4.07609
396 4FWE FAD 4.09483
397 4YSX FAD 4.09483
398 2Z3Y F2N 4.09483
399 6FHO FAD 4.09483
400 5WGR FAD 4.09483
401 1Y8Q ATP 4.09483
402 5YB7 FAD 4.09483
403 5YB7 ORN 4.09483
404 5KOX FAD 4.09483
405 5KOX RFP 4.09483
406 5X20 NAD 4.09483
407 4KRG SAH 4.09483
408 2GCG NDP 4.09483
409 2GUD BMA 4.09836
410 2GUD MAN 4.09836
411 2GUC MAN 4.09836
412 2NUO BGC 4.09836
413 2HYR BGC GLC 4.09836
414 2HYQ MAN MAN 4.09836
415 2NU5 NAG 4.09836
416 1VL0 NAI 4.10959
417 3B20 NAD 4.12979
418 3B1J NAD 4.12979
419 1O94 ADP 4.16667
420 3DCM SAM 4.16667
421 1Z82 NDP 4.1791
422 1GUZ NAD 4.19355
423 6EL3 NAP 4.19948
424 4KOA NDP 4.2042
425 4OM8 NAD 4.20712
426 2GLX NDP 4.21687
427 5IDB MAN 4.22535
428 5IDB BMA 4.22535
429 1TL2 NDG 4.23729
430 2B9W FAD 4.24528
431 3AB4 LYS 4.27553
432 3AB4 THR 4.27553
433 1T9D P22 4.2836
434 6AIN FAD 4.30622
435 3IHG FAD 4.31034
436 5BRT FAD 4.31034
437 4TXI FAD 4.31034
438 2BRY FAD 4.31034
439 2ZXI FAD 4.31034
440 5BRT CH9 4.31034
441 5MQ6 NDP 4.31034
442 4C3Y FAD 4.31034
443 5FJN FAD 4.31034
444 5FJN BE2 4.31034
445 1COY FAD 4.31034
446 1GTE FAD 4.31034
447 4C3Y ANB 4.31034
448 2AQJ TRP 4.31034
449 2AQJ FAD 4.31034
450 4U8P FDA 4.31034
451 1GQ2 NAP 4.31034
452 1COY AND 4.31034
453 4U8P UDP 4.31034
454 9LDT NAD 4.31034
455 3UOY FAD 4.31034
456 3UOY NAP 4.31034
457 9LDB NAD 4.31034
458 3ORF NAD 4.31034
459 2HI4 BHF 4.31034
460 1YKJ FAD 4.31472
461 1YKJ PHB 4.31472
462 3A25 SAM 4.31894
463 3ZNN 4WL 4.32277
464 3ZNN FAD 4.32277
465 2BOY BHO 4.33071
466 1WY7 SAH 4.34783
467 5H81 NAP 4.37018
468 4XDZ NDP 4.37318
469 3A4T SFG 4.37956
470 1LLU NAD 4.38596
471 4KRI SAH 4.38799
472 6HKE LMR 4.40252
473 6HKE MLT 4.40252
474 4ZGS NAD 4.40415
475 5I39 FAD 4.41176
476 2YG3 FAD 4.41501
477 1RJW ETF 4.42478
478 3FUU ADN 4.42804
479 5X62 SAH 4.4335
480 5ZBC FAD 4.43459
481 2QV7 ADP 4.45104
482 2VOH CIT 4.4586
483 3DMH SAM 4.46194
484 1ZGA SAH 4.48179
485 2XYQ SAH 4.48276
486 2XWL CTP 4.4843
487 1IY8 NAD 4.49438
488 1DSS NAD 4.5045
489 4RPL FAD 4.51128
490 4RPL 3UC 4.51128
491 2DKH FAD 4.52586
492 4REP FAD 4.52586
493 5TS5 FAD 4.52586
494 2DKH 3HB 4.52586
495 4AT0 FAD 4.52586
496 3AYI FAD 4.52586
497 3AYI HCI 4.52586
498 1DMH MCT 4.52586
499 3C6K SPD 4.52586
500 4J1Q NDP 4.52586
501 4ZVV GN0 4.52586
502 3C6K MTA 4.52586
503 4ZVV NAD 4.52586
504 1UAY ADN 4.54545
505 4TSK NDP 4.57143
506 1NJR XYL 4.57746
507 1WPQ NAD 4.58453
508 3DXY SAM 4.58716
509 5EZ7 FAD 4.59184
510 1E3W NAD 4.5977
511 1R37 NAD 4.61095
512 1E6W NAD 4.61538
513 5TWB FAD 4.65116
514 2DC1 NAD 4.66102
515 5TQZ GLC 4.66667
516 2PK3 A2R 4.6729
517 1C0I BE2 4.6832
518 1C0I FAD 4.6832
519 2JJQ SAH 4.70588
520 5A04 NDP 4.71976
521 5A04 BGC 4.71976
522 1REO FAD 4.73251
523 1NAA 6FA 4.74138
524 1NAA ABL 4.74138
525 1O0S NAI 4.74138
526 5HS2 CTP 4.74138
527 4CJX NAP 4.74138
528 6GNC FAD 4.7619
529 3HGM ATP 4.7619
530 4RF2 NAP 4.77941
531 4UCI SAM 4.81928
532 1DJL NAP 4.83092
533 3AY6 NAI 4.83271
534 4OPC PGT 4.85651
535 4OPC FDA 4.85651
536 6GNA FAD 4.86111
537 6GAR FAD 4.87106
538 6A3J NAI 4.87805
539 4BJZ P3A 4.95283
540 4BJZ FAD 4.95283
541 4HA6 FAD 4.9569
542 4FE2 AIR 4.9569
543 3GGO NAI 4.9569
544 3GGO ENO 4.9569
545 1RYI FAD 4.97382
546 1RYI GOA 4.97382
547 5G6U TRP 4.98084
548 3C1O NAP 4.98442
549 5YEC ATP 5
550 1EJ0 SAM 5
551 2V6A CAP 5
552 1LTH NAD 5.01567
553 3WMX NAD 5.02793
554 2PWY SAH 5.03876
555 4ONQ SFG 5.04202
556 3WV8 ATP 5.04587
557 2WA2 SAM 5.07246
558 3KB6 NAD 5.08982
559 4LNU GDP 5.09978
560 1JG3 ADN 5.10638
561 4CNK FAD 5.11509
562 1KJ8 GAR 5.11509
563 3I53 SAH 5.12048
564 5BVA FAD 5.13447
565 1J5P NAD 5.13834
566 5FEU NAP 5.15464
567 1GV0 NAD 5.16129
568 5N0J FAD 5.17241
569 2DFV NAD 5.17241
570 2O4C NAD 5.17241
571 6BII NAP 5.17241
572 2ZFU SAH 5.17241
573 3ABI NAD 5.20548
574 1Y9Q MED 5.20833
575 3K5I AIR 5.21092
576 3FPZ AHZ 5.21472
577 5D4V SAH 5.22388
578 1UZD CAP 5.22388
579 1DIG NAP 5.22876
580 4P5E N6P 5.26316
581 2RGO FAD 5.27183
582 4JNA FAD 5.29412
583 1RL4 BRR 5.31915
584 4XDY NAI 5.32544
585 4CQM NAP 5.32787
586 2YX1 SFG 5.35714
587 1ZGS XMM 5.36913
588 4NTC FAD 5.37313
589 4XFR CIT 5.38642
590 4NTD FAD 5.38793
591 4J36 1HR 5.38793
592 4J36 FAD 5.38793
593 3ULK NDP 5.38793
594 5ZXD ATP 5.38793
595 4DPL NAP 5.38793
596 4PLG NAI 5.38922
597 4PLG OXM 5.38922
598 2Q0L FAD 5.46624
599 2Q0L NAP 5.46624
600 1E6E FAD 5.46875
601 2C7G FAD 5.48246
602 2C7G ODP 5.48246
603 5OCM NAP 5.49828
604 5MGZ SAH 5.50847
605 2NU8 COA 5.55556
606 3TTZ 07N 5.55556
607 2R4J FAD 5.58882
608 2R4J 13P 5.58882
609 2D3N GLC GLC GLC 5.60345
610 2RGH FAD 5.6042
611 2IU8 PLM 5.61497
612 5JE8 NAD 5.62914
613 1YS4 NAP 5.64972
614 1ELI PYC 5.65553
615 1DL5 SAH 5.67823
616 2DT5 NAD 5.6872
617 5N5D SAM 5.75221
618 3LU1 NAD 5.76923
619 1GY8 NAD 5.79345
620 2HK9 ATR 5.81818
621 2HK9 NAP 5.81818
622 1KYQ NAD 5.81897
623 2E5V FAD 5.81897
624 3H8V ATP 5.82192
625 5FFF NAP 5.83658
626 5A1T OXM 5.8651
627 5A1T NAI 5.8651
628 2A92 NAI 5.919
629 1L1E SAH 5.92335
630 2DPM SAM 5.98592
631 3OFK SAH 6.01852
632 1KYZ SAH 6.0274
633 3OJO NAD 6.03248
634 5K0A FAD 6.06061
635 5KKA 6V0 6.08974
636 1ZEM NAD 6.10687
637 5TUF FAD 6.11247
638 5TUF TDC 6.11247
639 4GPS CIT 6.14657
640 5N53 8NB 6.15385
641 4D79 ATP 6.15942
642 5O4J PJL 6.20438
643 5O4J 9KH 6.20438
644 5O4J SAH 6.20438
645 5BW4 SAM 6.25
646 3H5N ATP 6.25
647 2GNK ATP 6.25
648 1GZ4 ATP 6.25
649 3S5W NAP 6.2635
650 3S5W FAD 6.2635
651 1O6Z NAD 6.27063
652 1RP0 AHZ 6.33803
653 5NM7 GLY 6.39098
654 2ZIF SAM 6.39731
655 3HQP FDP 6.41283
656 2CVQ NDP 6.42202
657 1EBF NAD 6.42458
658 3O7W SAM 6.46258
659 4B4U NAP 6.46552
660 1D1T NAD 6.46552
661 1F8F NAD 6.46552
662 2F7A BEZ 6.46552
663 1GPM CIT 6.46552
664 1DLJ UGA 6.46766
665 1DLJ NAI 6.46766
666 2VDV SAM 6.50407
667 3ITJ FAD 6.50888
668 3ITJ CIT 6.50888
669 5M58 SAH 6.52174
670 1MR3 G3D 6.62983
671 3EW2 BTN 6.66667
672 2JHP SAH 6.68103
673 1M2K APR 6.68103
674 4UP3 FAD 6.6879
675 4UP3 NDP 6.6879
676 2F5X ASP 6.73077
677 4RSL FAD 6.74157
678 1BXK NAD 6.76056
679 2BFR ADP 6.77083
680 5GT9 NAP 6.84411
681 3L4S NAD 6.84524
682 3L4S 3PG 6.84524
683 5UR0 NAD 6.87679
684 5EES NAP 6.88259
685 5JCA FAD 6.89655
686 2CUL FAD 6.89655
687 5JCA NDP 6.89655
688 6H3O FAD 6.89655
689 4C4A SAH 6.89655
690 3LST SAH 6.89655
691 4USQ FAD 6.92521
692 2VYN NAD 6.94864
693 5ZI2 NAD 6.95652
694 5ZI2 ADP 6.95652
695 1TDF FAD 6.96203
696 1TDF NAP 6.96203
697 1HTW ADP 6.96203
698 1GAD NAD 6.9697
699 3DAG FEG 6.98324
700 1LDM NAD 6.99088
701 3RYC GDP 6.99301
702 2EFJ SAH 7.03125
703 4MIG G3F 7.11207
704 5LOG SAH 7.11207
705 1Z45 NAD 7.11207
706 6FDF SAH 7.11207
707 5ODQ FAD 7.14286
708 5XVH NAP 7.18954
709 5ZZ6 ADP 7.21154
710 5ZZ6 NAD 7.21154
711 3TLJ SAH 7.23861
712 1LDN NAD 7.27848
713 2QA1 FAD 7.32759
714 1KEV NDP 7.40741
715 4E13 NAD 7.42049
716 1VJT NAD 7.45342
717 2BNE U5P 7.46888
718 3X0V FAD 7.5431
719 3HVJ 705 7.69231
720 4L8V NAP 7.71513
721 1P77 ATR 7.72059
722 5YRJ BGC GLC 7.74648
723 5YRG BGC GLC 7.74648
724 5YRF GLC GLC 7.74648
725 4XB2 NDP 7.76119
726 4XB2 HSE 7.76119
727 2QQF A1R 7.79221
728 4XUC SAM 7.79817
729 4XUC 43G 7.79817
730 3RFV 15L 7.86517
731 6BWL NAD 7.92683
732 5D1R 56S 7.94979
733 3QVP FAD 7.97414
734 1KPH SAH 8.01394
735 2G77 AF3 8.04878
736 3OZ2 FAD 8.06045
737 4GUS FAD 8.06452
738 4HSU FAD 8.06452
739 4GUT FAD 8.06452
740 1LVW TYD 8.13559
741 1I8T FAD 8.17439
742 6F3M NAD 8.18966
743 3T7S SAM 8.20895
744 5KVA SAM 8.27338
745 4RDH AMP 8.33333
746 2HMT NAI 8.33333
747 4RDI ATP 8.33333
748 4GKV NAD 8.33333
749 1VM6 NAD 8.33333
750 4O0L NDP 8.36364
751 5UAO FAD 8.40517
752 4Y9D NAI 8.40517
753 3JUC PCA 8.49673
754 2EB5 OXL 8.61423
755 1PL6 NAD 8.62069
756 1PL6 572 8.62069
757 5TCI MLI 8.69565
758 1XHC FAD 8.71935
759 4M37 SAH 8.74636
760 2IVD FAD 8.78661
761 2IVD ACJ 8.78661
762 2G5C NAD 8.83621
763 1SOW NAD 8.83621
764 1OBB NAD 8.83621
765 1C3M MAN MAN 8.84354
766 3AD8 NAD 8.91089
767 3KO0 TFP 8.91089
768 3AD8 PYC 8.91089
769 3AD8 FAD 8.91089
770 1HDR NAD 9.01639
771 2Q2V NAD 9.01961
772 5TTJ FAD 9.05172
773 3FPF MTA 9.0604
774 3FPF TNA 9.0604
775 1OFS SUC 9.09091
776 4FZV SAM 9.20502
777 1HKU NAD 9.21788
778 1WDK NAD 9.23077
779 3U4C NDP 9.25267
780 3T31 FAD 9.26724
781 3T31 DCQ 9.26724
782 2VHW NAI 9.26724
783 1C1X NAD 9.29577
784 2BGM NAJ 9.35252
785 1C3V NDP 9.38776
786 6F97 FAD 9.48276
787 5A0U CHT 9.48276
788 3GF4 FAD 9.48718
789 3GF4 UPG 9.48718
790 4POO SAM 9.5
791 1ORR NAD 9.51009
792 4MO2 FDA 9.51087
793 4MO2 FAD 9.51087
794 1BW9 NAD 9.55056
795 1BXG NAD 9.55056
796 1NYT NAP 9.5941
797 5Y77 FAD 9.69828
798 5MZI FAD 9.69828
799 5MZI FYK 9.69828
800 4XZ3 COA 9.69828
801 5JWC FAD 9.78887
802 3VSE SAH 9.799
803 2PHN GDP 9.84252
804 3GD8 GOL 9.86547
805 2YY7 NAD 9.9359
806 1LSS NAD 10
807 1JNR FAD 10
808 2CVZ NDP 10.0346
809 1UJ5 5RP 10.1322
810 3A27 SAM 10.2941
811 2OOR NAD 10.3448
812 1L7E NAI 10.3448
813 3NJ4 NAD 10.3448
814 3NJ4 AFX 10.3448
815 1E3I CXF 10.3723
816 3G89 SAM 10.4418
817 5K9B FMN 10.5556
818 1F8G NAD 10.5603
819 3LZW FAD 11.1446
820 3LZW NAP 11.1446
821 3MB5 SAM 11.3725
822 1L7N ALF 11.3744
823 1MFI FHC 11.4035
824 5YAP NAI 11.4224
825 5YAP 8S0 11.4224
826 6GAS FAD 11.4804
827 3TKA SAM 11.5274
828 5OC1 FAD 11.6379
829 5MVR ADP 11.7284
830 1EDO NAP 11.8852
831 5X2N ALA 11.9816
832 1FL2 FAD 12.2845
833 4YKG FAD 12.2845
834 4YKG NAD 12.2845
835 5XQW 8EU 12.3223
836 2CJU PHX 12.3967
837 5KMS FAD 12.7155
838 5KMS NAD 12.7155
839 3WLE NAD 12.9032
840 1A0J BEN 13.0045
841 5FA8 SAM 13.0435
842 1LUA NAP 13.3621
843 3K56 IS3 13.5338
844 5TC4 NAD 13.6076
845 2X6T NAP 14.0056
846 3AB1 FAD 14.0086
847 1EZ4 NAD 14.1509
848 1NM5 NAD 14.2857
849 3GDH SAH 14.5228
850 2XVF FAD 14.6552
851 2XVE FAD 14.8707
852 2GAG NAD 15.1515
853 2GAG FAD 15.1515
854 2GAG FOA 15.1515
855 3SHR CMP 15.3017
856 1VDC FAD 15.3153
857 5L95 AMP 16.25
858 5EIN NAP 16.6667
859 3C3Y SAH 16.8776
860 3EGI ADP 16.9903
861 5GSN MMZ 17.6724
862 5GSN FAD 17.6724
863 5GSN NAP 17.6724
864 3HYK A3P 18.0328
865 6F5Z SAH 18.1818
866 4BV6 FAD 18.319
867 4TM3 FAD 18.319
868 3GD4 FAD 18.75
869 3GD4 NAD 18.75
870 4M38 SAH 19.0476
871 2D2F ADP 19.2
872 5FA5 MTA 20
873 3LXD FAD 20.4741
874 3CTY FAD 20.6897
875 2CDU ADP 20.7965
876 2CDU FAD 20.7965
877 1Q1R FAD 20.8817
878 3FG2 FAD 21.5347
879 5JCM FAD 22.1983
880 5JCM ISD 22.1983
881 5JCM NAD 22.1983
882 2YVJ FAD 22.7941
883 2YVJ NAI 22.7941
884 2YVF FAD 22.7941
885 2YVF NAD 22.7941
886 2Z6J TUI 22.8916
887 5NA1 FAD 24.7549
888 4EMI FAD 25
889 4EMJ FAD 25
890 2NPX FAD 25
891 4EMI NAD 25
892 2NPX NAD 25
893 4II2 ATP 25.1534
894 3ICT ADP 25.2155
895 3ICS ADP 25.2155
896 3ICR FAD 25.2155
897 3ICS FAD 25.2155
898 3ICT FAD 25.2155
899 3QV1 NAD 25.6098
900 1YQZ FAD 25.8621
901 3CGB FAD 26.7241
902 3KLJ FAD 26.7532
903 5J60 FAD 26.9397
904 3F8D FAD 28.4483
905 3CGD NAD 29.0948
906 3CGD COA 29.0948
907 3CGD FAD 29.0948
908 3NT6 FAD 30.1724
909 3NTA FAD 30.1724
910 3NTD FAD 31.25
911 5VN0 FAD 31.4655
912 5VN0 NAI 31.4655
913 2Q7V FAD 35.0769
914 5MIT FAD 38.8379
915 5MIT NAP 38.8379
916 1MO9 FAD 40.7328
917 1MO9 KPC 40.7328
918 4J56 FAD 43.319
919 2HQM FAD 43.75
920 5NII FAD 44.3366
921 1GET FAD 44.8889
922 1GET NAP 44.8889
923 1FEC FAD 45.2586
924 6FP4 FAD 45.2586
925 6FP4 E1T 45.2586
926 3QFA FAD 45.4741
927 1BZL FAD 45.4741
928 2NVK FAD 45.4741
929 1ZK7 FAD 45.4741
930 1BZL GCG 45.4741
931 2NVK NAP 45.4741
932 2WPF FAD 45.4741
933 2WPF WPF 45.4741
934 3SQP FAD 46.1207
935 2RAB FAD 47.0842
936 2RAB NAD 47.0842
Pocket No.: 2; Query (leader) PDB : 2A8X; Ligand: FAD; Similar sites found with APoc: 136
This union binding pocket(no: 2) in the query (biounit: 2a8x.bio1) has 44 residues
No: Leader PDB Ligand Sequence Similarity
1 4A59 AMP 1.07759
2 4R5Z SIN 1.3624
3 2C29 NAP 1.48368
4 2BHZ MAL 1.50862
5 5WP4 SAH 1.50862
6 4U63 MHF 1.60643
7 1IZC PYR 1.76991
8 3BGD SAH 1.92308
9 3ZGE ASP 1.93966
10 4JUI EGR 1.93966
11 4MP8 NAD 2.0649
12 4MP8 MLI 2.0649
13 5E9W SAH 2.24359
14 5E8J SAH 2.24359
15 3K6V CIT 2.25989
16 5A3B APR 2.31023
17 4YAC NAI 2.3569
18 3EF0 ALF 2.37069
19 2GND MAN 2.38095
20 2PHF MAN MAN 2.38095
21 2GND MAN MMA 2.38095
22 2PHR MAN MAN 2.38095
23 2PHR MAN MAN BMA MAN 2.38095
24 5G4L NDP 2.44755
25 1GZ6 NAI 2.50784
26 3BXO SAM 2.51046
27 5NE2 DGL 2.51799
28 2VSS V55 2.53623
29 2IZ1 ATR 2.58621
30 2UZ1 TPP 2.58621
31 3ZF8 GDP 2.62295
32 3FXU TSU 2.62295
33 4DCM SAM 2.66667
34 1JQD SAH 2.73973
35 2CFC KPC 2.8
36 2WK1 SAH 2.83688
37 2Q1S NAI 2.91777
38 3H2B SAH 2.95567
39 2Q28 ADP 3.01724
40 1US5 GLU 3.18471
41 5VYH FOL 3.207
42 1IM8 SAI 3.27869
43 3LRE ADP 3.66197
44 5FUI APY 3.78788
45 1G55 SAH 3.79009
46 2OQ5 BEN 3.87931
47 3P2E SAH 4
48 1QRD DQN 4.0293
49 1IZO PAM 4.07674
50 2FWP ICR 4.09483
51 3JQA NAP 4.16667
52 5K6A NAP 4.16667
53 3BMQ NAP 4.16667
54 3BMO NAP 4.16667
55 5JDI NAP 4.16667
56 3JQF NAP 4.16667
57 3JQ8 NAP 4.16667
58 3JQ7 NAP 4.16667
59 5JCJ NAP 4.16667
60 4CM4 NAP 4.16667
61 3JQ9 NAP 4.16667
62 4CM8 NAP 4.16667
63 5JDC NAP 4.16667
64 3BMN NAP 4.16667
65 4CMI NAP 4.16667
66 4CLR NAP 4.16667
67 3JQG NAP 4.16667
68 4CM9 NAP 4.16667
69 1GVF PGH 4.1958
70 5LX9 OLB 4.23453
71 2YIV YIV 4.31034
72 5MTE BB2 4.37956
73 3ZG6 APR 4.39189
74 1TE2 PGA 4.42478
75 3DMH GMP 4.46194
76 4TWL ASC 4.47154
77 2VAR AMP 4.47284
78 2UYQ SAM 4.51613
79 5NC1 NAG 4.64135
80 2D0O ADP 4.8
81 4G7A AZM 4.83871
82 2WD7 NAP 4.85075
83 2WKW W22 4.87805
84 3GU3 SAH 4.92958
85 2XOC ADE 4.98084
86 1PNO NAP 5
87 1G6H ADP 5.05837
88 1RZU ADP 5.15464
89 3QOX SAH 5.16432
90 6FA4 GNP 5.20231
91 5YF1 SFG 5.24862
92 1I1N SAH 5.30973
93 5OFW 9TW 5.38117
94 1D4O NAP 5.43478
95 4SGA ACE PRO ALA PRO PHE 5.52486
96 5YRL GLC GLC 5.6338
97 6E8I PTR 5.91716
98 3RF4 FUN 6.03448
99 3JWH SAH 6.45161
100 4AZW SAM 6.46552
101 1LK7 DER 6.55022
102 2JHP GUN 6.68103
103 5WGQ EST 6.89655
104 5WGD EST 6.89655
105 3OND ADN 7.32759
106 3OND NAD 7.32759
107 2XVM SAH 7.53769
108 4IF4 BEF 8.17308
109 5N18 8HZ 8.25688
110 4NZF ARB 8.48214
111 4UBP