Receptor
PDB id Resolution Class Description Source Keywords
1ypj 1.78 Å EC: 3.4.21.5 THROMBIN INHIBITOR COMPLEX HOMO SAPIENS THROMBIN INHIBITOR COMPLEX BARREL 6 STRANDED BETA-SHEET CLOTTING-HYDROLASE INHIBITOR COMPLEX
Ref.: A SIMPLE PROTOCOL TO ESTIMATE DIFFERENCES IN PROTEI AFFINITY FOR ENANTIOMERS WITHOUT PRIOR RESOLUTION O RACEMATES ANGEW.CHEM.INT.ED.ENGL. V. 45 985 2006
Ligand Information
Ligand Validity Binding Data Ligand Warnings Chemaxon Viewer Molecular Weight (Da) Formula SMILES
UIB Valid Ki = 95 nM none 448.557
C26 H32 N4 O3
CC[C@@H]1[C@@H]2[C@@H]([C@@H]([N@](C2(C)C)C)c3ccc(cc3)C(=N)N)C(=O)N1Cc4ccc5c(c4)OCO5
90% Homology Family

The Class containing this family consists of a total of 71 families.

Leader:    1YPE     THROMBIN INHIBITOR COMPLEX
No: PDB id Binding Data Representative ligand
1 1YPE Ki = 8 nM UIP
2 3U8T Ki = 16.5 uM DPN PRO DAR CYS NH2
3 1EB1 Ki = 37 pM ALC PRO MMO
4 1YPM Ki = 1.9 uM RA4
5 1YPJ Ki = 95 nM UIB
6 1YPK - ASP PHE GLU GLU ILE PRO GLU GLU TYS LEU
7 1YPG Ki = 10 nM UIR
8 1SB1 Ki = 128 nM 165
9 1TWX - ASP PHE GLU GLU ILE PRO GLY GLU STY LEU
10 1H8D - PHW
11 1VR1 - ASP PHE GLU GLU ILE PRO GLU GLU TYR LEU SFO
12 1H8I - ASP PHE GLU GLU ILE PRO GLU GLU TYS LEU
13 1YPL Ki = 10.6 uM RA8
14 3BV9 ic50 = 6.9 uM DAR OIC PRO DAL 4PH NH2
15 3U8R Ki = 7.7 uM DPN PRO DAR ILE NH2
16 3U8O Ki = 0.92 uM DPN PRO DAR DTH NH2
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